Medicine and Health Sciences Commons^™

Caring Near And Far By Connecting Community-Based Clients And Family Member/Friend Caregivers Using Passive Remote Monitoring: Protocol For A Pragmatic Randomized Controlled Trial, Lorie Donelle, Sandra Regan, Michael Kerr, Merrick Zwarenstein, Michael Bauer, Grace Warner, Wanrudee Isaranuwatchai, Aleksandra Zecevic, Elizabeth Borycki, Dorothy Forbes, Lori Weeks, Bev Leipert, Emily Read

Nursing Publications

Background: Significant chronic disease challenges exist among older adults. However, most older adults want to remain at home even if their health conditions challenge their ability to live independently. Yet publicly funded home care resources are scarce, private home care is expensive, and family/friend caregivers have limited capacity. Many older adults with chronic illness would require institutional care without the support from family member/friend caregivers. This role raises the risk of physical health problems, stress, burnout, and depression. Passive remote monitoring (RM), the use of sensors that do not require any action by the individual for the system to work, …

Cortical Activation During Shoulder And Finger Movements In Healthy Adults: A Functional Near-Infrared Spectroscopy (Fnirs) Study., Chieh-Ling Yang, Shannon B Lim, Sue Peters, Janice J Eng

Physical Therapy Publications

Characterization of cortical activation patterns during movement of the upper extremity in healthy adults is helpful in understanding recovery mechanisms following neurological disorders. This study explores cortical activation patterns associated with movements of the shoulder and fingers in healthy adults using functional near-infrared spectroscopy (fNIRS). Twelve healthy right-handed participants were recruited. Two motor tasks (shoulder abduction and finger extension) with two different trial lengths (10 s and 20 s) were performed in a sitting position at a rate of 0.5 Hz. The hemodynamic response, as indicated by oxy-hemoglobin (HbO) and deoxy-hemoglobin (HbR), over both hemispheres was acquired using a 54-channel …

Nox2 Is Critical To Endocardial To Mesenchymal Transition And Heart Development, Hoda Moazzen, Yan Wu, Anish Engineer, Xiangru Lu, Simran Aulakh, Qingping Feng

Paediatrics Publications

NADPH oxidases (NOX) are a major source of reactive oxygen species (ROS) production in the heart. ROS signaling regulates gene expression, cell proliferation, apoptosis, and migration. However, the role of NOX2 in embryonic heart development remains elusive. We hypothesized that deficiency of Nox2 disrupts endocardial to mesenchymal transition (EndMT) and results in congenital septal and valvular defects. Our data show that 34% of Nox2-/- neonatal mice had various congenital heart defects (CHDs) including atrial septal defects (ASD), ventricular septal defects (VSD), atrioventricular canal defects (AVCD), and malformation of atrioventricular and aortic valves. Notably, Nox2-/- embryonic hearts show abnormal development of …

Estimation Of Gfr In Patients With Cystic Fibrosis: A Cross-Sectional Study, Andrea Wallace, April Price, Erin Fleischer, Michael Khoury, Guido Filler

Paediatrics Publications

Background: Patients with cystic fibrosis (CF) have frequent infectious complications requiring nephrotoxic medications, necessitating monitoring of renal function. Although adult studies have suggested that cystatin C (CysC)-based estimated glomerular filtration rate (eGFR) may be preferable due to reduced muscle mass of patients with CF, pediatric patients remain understudied. Objective: Our objective was to determine which eGFR formula is best for estimating glomerular filtration rate (GFR) in pediatric patients with CF. Methods: A total of 17 patients with CF treated with nephrotoxic antibiotics were recruited from the Children’s Hospital at London Health Sciences Centre, London, Ontario, Canada. 99Tc DTPA GFR (measured …

Presence Of Benznidazole Conjugated Metabolites In Urine Identified By Β-Glucuronidase Treatment, María Elena Marson, Facundo García Bournissen, Jaime Altcheh, Guillermo Moscatelli, Samantha Moroni, Guido Enrique Mastrantonio

Paediatrics Publications

Chagas disease is a serious public health problem in Latin America and, due to migration, in other non-endemic regions. Benznidazole (BNZ) is first choice drug in pediatric therapeutics. However, little is known regarding its metabolism in humans. The aim of the study was to isolate and identify products of human BZN metabolism in urine samples obtained from a pediatric Chagas patient and a healthy adult volunteer both treated with BZN. Urine samples were collected after dose of BNZ. Urine was treated with β-glucuronidase followed by an extraction procedure under two different pH conditions and a HPLC/UV and MS/MS identification of …

After-Hours Incentives And Emergency Department Visits: Evidence From Ontario Forthcoming At Canadian Public Policy, Rose Anne Devlin, Koffi Ahoto Kpelitse, Lihua Li, Nirav Mehta, Sisira Sarma

Epidemiology and Biostatistics Publications

No abstract provided.

Evaluating The Effectiveness Of Aquatic Therapy On Mobility, Balance, And Level Of Functional Independence In Stroke Rehabilitation: A Systematic Review And Meta-Analysis., Alice Mary Iliescu, Amanda Mcintyre, Joshua C. Wiener, Jerome Iruthayarajah, Andrea Lee, Sarah Caughlin, Robert Teasell

Epidemiology and Biostatistics Publications

OBJECTIVE: To meta-analyze and systematically review the effectiveness of aquatic therapy in improving mobility, balance, and functional independence after stroke.

DATA SOURCES: Articles published in Medline, Embase, CINAHL, PsycINFO, and Scopus up to 20 August 2019.

STUDY SELECTION: Studies met the following inclusion criteria: (1) English, (2) adult stroke population, (3) randomized or non-randomized prospectively controlled trial (RCT or PCT, respectively) study design, (4) the experimental group received >1 session of aquatic therapy, and (5) included a clinical outcome measure of mobility, balance, or functional independence.

DATA EXTRACTION: Participant characteristics, treatment protocols, between-group outcomes, point measures, and measures of variability …

The Occupational Therapy Examination And Practice Preparation (Otepp) Program: Development, Implementation And Evaluation Of An Educational Program For Internationally-Educated Occupational Therapists, Colleen E. Mcgrath

Occupational Therapy Publications

This paper provides a chronological overview of the development, implementation, and evaluation of an educational initiative aimed at ensuring internationally-educated occupational therapists are prepared to enter practice in their new country, Canada. The three major phases of the program’s 12-year evolution are described, to distill the key lessons learned at each phase. Data related to the demographics of participants, program content, results of the national examination, registration, and employment outcomes are included. An enhanced understanding of the transition experience of internationally educated occupational therapists provides a strong foundation from which to support internationally-educated colleagues and strengthen the occupational therapy profession.

Centering The Complexity Of Long-Term Unemployment: Lessons Learned From A Critical Occupational Science Inquiry, Rebecca Aldrich, Debbie Rudman, Na Eon(Esther) Park, Suzanne Huot

Occupational Therapy Publications

Inquiries that rely on temporal framings to demarcate long-term unemployment risk generating partial understandings and grounding unrealistic policy solutions. In contrast, this four-phase two-context study aimed to generate complex understandings of post-recession long-term unemployment in North America. Grounded in a critical occupational perspective, this collaborative ethnographic study also drew on street-level bureaucracy and governmentality perspectives to understand how social policies and discursive constructions shaped people’s everyday ‘doing’ within the arena of long-term unemployment. Across three phases, study methods included interviews with 15 organizational stakeholders who oversaw employment support services; interviews, participant observations, and focus groups with 18 people who provided …

Occupational Therapists As Street-Level Bureaucrats: Leveraging The Political Nature Of Everyday Practice., Rebecca M Aldrich, Debbie Rudman

Occupational Therapy Publications

BACKGROUND.: As front-line service providers who often work in systems regulated by governmental bodies, occupational therapists can be conceptualized as "street-level bureaucrats" ( Lipsky, 1980/2010 ) who effect and are affected by policy.

PURPOSE.: Drawing on understandings from a study of long-term unemployment, this article proposes that occupational therapists, as street-level bureaucrats, respond to inter-related policies and systems in ways that can perpetuate, resist, or transform opportunities for doing and being.

KEY ISSUES.: By highlighting practitioners' everyday negotiation of governmental, organizational, and professional power relations, the notion of street-level bureaucracy illuminates the political nature of practice as well as the …

Supports For Migrant Farmworkers: Tensions In (In)Access And (In)Action, Susana Caxaj, Amy Cohen, Sarah Marsden

Health and Rehabilitation Sciences Publications

Purpose: This study examined the role of support actors in promoting or hindering access to migrant agricultural workers' (MAWs) needs, and, to determine the factors that influence adequate support for this population.
Methodology: Employing a Situational Analysis methodology, we carried out focus groups and interviews with 35 support actors complimented by a community scan (n=28) with public-facing support persons and a community consultation with migrant agricultural workers (MAWs).
Findings: Two major themes were revealed: (In)access and (In)action, and; Blurred Lines in Service Provision. The first illustrated how support actors could both reinforce or challenge barriers for this population through tensions …

Intrinsic Measures And Shape Analysis Of The Intratemporal Facial Nerve, Thomas Hudson, Bradley Gare, Daniel Allen, Hanif Ladak, Sumit Agrawal

Electrical and Computer Engineering Publications

Hypothesis: To characterize anatomical measurements and shape variation of the facial nerve within the temporal bone, and to create statistical shape models (SSMs) to enhance knowledge of temporal bone anatomy and aid in automated segmentation.

Background: The facial nerve is a fundamental structure in otologic surgery, and detailed anatomic knowledge with surgical experience are needed to avoid its iatrogenic injury. Trainees can use simulators to practice surgical techniques, however manual segmentation required to develop simulations can be time consuming. Consequently, automated segmentation algorithms have been developed that use atlas registration, SSMs, and deep learning.

Methods: Forty cadaveric temporal bones were …

Memory Function And Brain Functional Connectivity Adaptations Following Multiple-Modality Exercise And Mind-Motor Training In Older Adults At Risk Of Dementia: An Exploratory Sub-Study., Narlon C Boa Sorte Silva, Lindsay S Nagamatsu, Dawn P. Gill, Adrian M Owen, Robert J Petrella

Family Medicine Publications

BACKGROUND: Multiple-modality exercise improves brain function. However, whether task-based brain functional connectivity (FC) following exercise suggests adaptations in preferential brain regions is unclear. The objective of this study was to explore memory function and task-related FC changes following multiple-modality exercise and mind-motor training in older adults with subjective cognitive complaints.

METHODS: We performed secondary analysis of memory function data in older adults [

RESULTS: Our findings indicated that the M4 group showed greater improvements in the Paired Associates tasks compared to the M2 group at 24 weeks [mean difference: 0.47, 95% confidence interval (CI): 0.08 to 0.86,

CONCLUSION: Our findings …

Production Of Flavoured Fiti Probiotic Yoghurt For The London Community, Chengyu (Jennifer) Guo, Stephanie Huff, Maria Medina, Bob Gough, Sharareh Hekmat

Africa Western Collaborations Day 2020 Abstracts

No abstract provided.

Using A One Health Approach To Address The Challenges Posed By Tuberculosis At The Human-Animal Interface In Kajiado County In Kenya, Joel Zhang, Timpiyian Leseni, Francisco Olea-Popelka

Africa Western Collaborations Day 2020 Abstracts

No abstract provided.

Covid-19 Hospital Response In Canada And Kenya: A Comparative Study Of Practices At Aga Khan University Hospital Nairobi, Sunnybrook Health Sciences Centre, And University Hospital Network, Betty Wang

Africa Western Collaborations Day 2020 Abstracts

No abstract provided.

The Effect Of Interprofessional Conflict Resolution On Interprofessional Collaborative Practice Among Healthcare Providers In Hospitals, Sibylle Ugirase

Africa Western Collaborations Day 2020 Abstracts

No abstract provided.

Nurses' And Nurse Educator's Experiences Of Applying Knowledge And Skills To Clinical And Academic Settings In Rwanda After Participating As Learners In Paediatric Nursing Continuing Professional Development Program, Amy Olson, Yolanda Babenko-Mould, Donatilla Mukamana

Africa Western Collaborations Day 2020 Abstracts

No abstract provided.

Assessment Of The Medication Interruptions Among Nurses Working In Paediatric Unit At University Teaching Hospital Of Kigali, Aimable Nkurunziza, Geldine Chironda, Godfrey Katenda, Lakshmi Rajeswaran, Emmanuel Munyaneza, Madeleine Mukeshimana

Africa Western Collaborations Day 2020 Abstracts

No abstract provided.

A Literature Review Of Barriers To Scaling Up Vasectomy Among Men Of Reproductive Age In Nigeria: A Gender Perspective, Mary Ndu

Africa Western Collaborations Day 2020 Abstracts

No abstract provided.

Rwandan Nursing And Midwifery Faculty's Experiences Of Applying Knowledge About Teaching Methodology To Practice In Academic And Clinical Settings With Students, Jean Pierre Ndayisenga, Yolanda Babenko-Mould, Marilyn K. Evans, Madeleine Mukeshimana

Africa Western Collaborations Day 2020 Abstracts

No abstract provided.

What Are We Doing? Is Exporting Anti-Depressants Answer The Mental Health Needs Of The Global South?, Gojjam Limenih

Africa Western Collaborations Day 2020 Abstracts

No abstract provided.

Antenatal Care Utilization In The Fragile And Conflict-Affected Context Of The Democratic Republic Of The Congo, Bianca R. Ziegler, Moses Mosonsieyiri Kansanga, Yuji Sano, Joseph Kangmennaang, Daniel Kpienbaareh, Isaac Luginaah

Africa Western Collaborations Day 2020 Abstracts

No abstract provided.

Evaluation Of Cytokine Profiles Within The Endocervical Tract Of Hiv-1 Infected Females, Steven M. Trothen, Rajesh A. Jacob, Genevieve Gosselin, Michael Fraser, Eric J. Arts, Jimmy D. Dikeakos

Africa Western Collaborations Day 2020 Abstracts

No abstract provided.

The Epidemiology Of Overweight And Obesity In Ghana: Examination Of Predictors And Risk Groups Among Women Of Childbearing Age, Jason Mulimba Were, Emmanuel Kojo Kyeremeh, Bridget Annor, Saverio Stranges

Africa Western Collaborations Day 2020 Abstracts

No abstract provided.

Effect Of Physical Maturation And Sexual Debut On Hiv Susceptibility In Adolescent Males In Rakai, Uganda, Zhongtian (Eric) Shao, Godfrey Kigozi, Ronald M. Galiwango, Cindy Liu, Rupert Kaul, Aaron Ar Tobian, Jessica Prodger

Africa Western Collaborations Day 2020 Abstracts

No abstract provided.

Malaria Elimination, Gurleen Saini, Anusheh Khan, Priscilla Matthews

Africa Western Collaborations Day 2020 Abstracts

No abstract provided.

Using A One Health Approach To Address The Challenges Posed By Rabies To Animals And People In Rural Areas In Victoria Falls, Zimbabwe, Ryan Lapenna, Isaac Moyo, Jessica Dawson, Chris Foggin, Francisco Olea-Popelka

Africa Western Collaborations Day 2020 Abstracts

No abstract provided.

An Upstream Approach To Diarrheal Disease, Ayah Karra Aly, Adaku Ohuruogu, Georgia Leigh Raithby, Jasandeep Sehra

Africa Western Collaborations Day 2020 Abstracts

No abstract provided.

Through The Lens Of Egocentric Design: Do Aya Males' Social Networks Influence Or Shape Their Srh Literacy And Information Behaviour?, Ebenezer Martin-Yeboah

Africa Western Collaborations Day 2020 Abstracts

No abstract provided.