Medicine and Health Sciences Commons^™

Fetal Diagnosis And Therapy During The Covid-19 Pandemic: Guidance On Behalf Of The International Fetal Medicine And Surgery Society, J Deprest, M Choolani, F Chervenak, D Farmer, K Lagrou, E Lopriore, L Mccullough, O Olutoye, L Simpson, G Ryan, +1 Additional Author

Journal Articles

No abstract provided.

Fetal Interventions In The Setting Of The Coronavirus Disease 2019 Pandemic: Statement From The North American Fetal Therapy Network, Mo Bahtiyar, A Baschat, J Deprest, S Emery, Wh Goodnight, A Johnson, L Mccullough, Js Moldenhauer, G Ryan, M Zaretsky, +3 Additional Authors

Journal Articles

No abstract provided.

Immunotherapies For Covid-19: Lessons Learned From Sepsis, Ke Remy, Sc Brakenridge, B Francois, T Daix, Cs Deutschman, G Monneret, R Jeannet, Pf Laterre, Rs Hotchkiss, Ll Moldawer

Journal Articles

No abstract provided.

Letter: Considerations For Performing Emergent Neurointerventional Procedures In A Covid-19 Environment., As Pandey, Aj Ringer, A Rai, Pt Kan, Pm Jabbour, A Siddiqui, E Levy, Kv Snyder, Ha Riina, D Langer, +9 Additional Authors

Journal Articles

No abstract provided.

Management Of Elective Aortic Valve Replacement Over The Long Term In The Era Of Covid-19, C Basman, Ca Kliger, L Pirelli, Sj Scheinerman

Journal Articles

No abstract provided.

Neutrophil Extracellular Traps In Covid-19., Y Zuo, S Yalavarthi, H Shi, K Gockman, M Zuo, Ja Madison, C Blair, A Weber, Bj Barnes, M Egeblad, Rj Woods, Y Kanthi, Js Knight

Journal Articles

No abstract provided.

Pediatric Covid-19-Associated Rhabdomyolysis: A Case Report, Am Gefen, N Palumbo, Sk Nathan, Ps Singer, Lj Castellanos-Reyes, Cb Sethna

Journal Articles

No abstract provided.

Powerless In The Icu: Perspectives From Intensive Care Units In The Face Of Covid-19., P Ramachandran, L Swamy, V Kaul, A Agrawal, M Narasimhan

Journal Articles

No abstract provided.

Preparing For The Covid-19 Pandemic: Our Experience In New York, Z Hasan, M Narasimhan

Journal Articles

No abstract provided.

Presenting Characteristics, Comorbidities, And Outcomes Among 5700 Patients Hospitalized With Covid-19 In The New York City Area, S Richardson, Js Hirsch, M Narasimhan, Jm Crawford, T Mcginn, Kw Davidson, Northwell Covid-19 Research Consortium

Journal Articles

No abstract provided.

Scientific And Standardization Committee Communication: Clinical Guidance On The Diagnosis, Prevention And Treatment Of Venous Thromboembolism In Hospitalized Patients With Covid-19., Ac Spyropoulos, Jh Levy, W Ageno, Jm Connors, Bj Hunt, T Iba, M Levi, Cm Samama, D Giannis, Jd Douketis, +1 Additional Author

Journal Articles

No abstract provided.

Tissue Plasminogen Activator (Tpa) Treatment For Covid-19 Associated Acute Respiratory Distress Syndrome (Ards): A Case Series, J Wang, N Hajizadeh, Ee Moore, Rc Mcintyre, Pk Moore, La Veress, Mb Yaffe, Hb Moore, Cd Barrett

Journal Articles

No abstract provided.

Which Country Is Truly Developed? Covid-19 Has Answered The Question, Js Freed, Sy Kwon, Hj El, M Gottlieb, R Roth

Journal Articles

No abstract provided.

Cerebral Venous Thrombosis: A Typical Presentation Of Covid-19 In The Young, De Klein, R Libman, C Kirsch, R Arora

Journal Articles

No abstract provided.

Treatment Of Clostridioides Difficile With Fecal Microbiota Transplantation, Brenton Green

Physician Assistant Scholarly Project Posters

Research was performed to discuss the epidemiology and current guidelines of Clostridioides difficile infection (CDI), recurrent C. difficile infection (rCDI), the different modalities of fecal microbiota transplantation (FMT), the donor screening process, as well as the safety and efficacy of treatment.

• Utilizing Clinical Key, NCBI database, Dynamed Plus, Cochrane Review, and the websites for the CDC and FDA, a literature review encompassing recent research and human studies relating to CDI.

• Recent studies within five years were preferred, however since C. difficile has sparsely changed, older data was utilized with updates applied accordingly.

• Oral antibiotics are intended for …

Impact Of Access Cavity Design On Peri-Cervical Dentin Removal In 3d Printed Tooth Models, James A. Mcintosh, Ove A. Peters, Christine Peters, Craig Dunlap

Orthodontics and Endodontics Theses

Aims Preservation of peri-cervical dentin during the preparation of endodontic access is important to prevent fractures and improve the long-term prognosis. The purpose of this study was to evaluate the impact of rotary file instrumentation (TruNatomy and XP-Endo Shaper) on peri-cervical dentin removal, depending on access size. Materials and Methods Forty 3D printed mandibular first molars, with either a small or large access design, were instrumented using TruNatomy or XP-endo Shaper file systems. Canal volumes were calculated based on micro-computed tomography data obtained pre- and post-operatively. Digital sectioning of each reconstructed volume was performed 90-degrees to the long axis at …

Ada Constitution & Bylaws (2020), American Dental Association

Constitution & Bylaws

The ADA Commons Constitution & Bylaws archival collection comprises printed issues of the American Dental Association's Constitution and Bylaws. The collection also includes the ADA Charter and the ADA Code of Ethics issued 1924-1946.

Survival Of A Serotype 4b Strain And A Serotype 1/2a Strain Of Listeria T Monocytogenes, Isolated From A Stone Fruit Outbreak Investigation, On Whole Stone Fruit At 4 °C, Antonio J. De Jesus, Ishani Sheth, Hee Jin Kwon, Zhujun Gao, Jessica Palmer, Minji Hur, Thomas S. Hammack, Dumitru Macarisin, Yi Chen

United States Food and Drug Administration: Publications

In the summer of 2014, a multistate outbreak of listeriosis associated with contaminated stone fruit (peach and nectarine) was reported. A serotype 4b variant Listeria monocytogenes (Lm) strain of singleton Sequence Type (ST) 382 was isolated from clinical samples and stone fruit associated with the outbreak. A serotype 1/2b Lm strain of ST5, Clonal Complex 5 was isolated only from outbreak-associated stone fruit, not from clinical samples. Here we investigated the fate of the serotype 4b and 1/2b strains, at two inoculation levels (high level at 3.7 logCFU/fruit and low level at 2.7 logCFU/fruit), on the surfaces of white peach, …

Adult Perceptions Of The Relative Harm Of Tobacco Products And Subsequent T Tobacco Product Use: Longitudinal Findings From Waves 1 And 2 Of The Population Assessment Of Tobacco And Health (Path) Study, Tara Elton-Marshall, Pete Driezen, Geoffrey T. Fong, K. Michael Cummings, Alexander Persoskie, Olivia Wackowski, Kelvin Choi, Annette Kaufman, David Strong, Shannon Gravely, Kristie Kristie, Jonathan Kwan, Maansi Bansal-Travers, Mark Travers, Andrew Hyland

United States Food and Drug Administration: Publications

Objectives: To examine: (1) How perceptions of harm for seven non-cigarette tobacco products predict sub- sequent use; (2) How change in use is associated with changes in perceptions of product harm; (3) Whether sociodemographic variables moderate the association between perceptions and use.

Methods: Data are from the adult sample (18+) of the Population Assessment of Tobacco and Health (PATH) Study, a nationally representative longitudinal cohort survey conducted September 2013-December 2014 (Wave 1 (W1) n = 32,320) and October 2014-October 2015 (Wave 2 (W2) n = 28,362).

Results: Wave 1 users and non-users of e-cigarettes, filtered cigars, cigarillos, and pipes, who …

An Evaluation Of The Usda's Policy To Reduce Listeria Illnesses In Ready‐To‐Eat Meat And Poultry Products, Travis Minor, Matt Parrett

United States Food and Drug Administration: Publications

Using 1998–2008 data collected by the Centers for Disease Control and Prevention on foodborne illnesses and outbreaks, we examine the economic impact of the United States Department of Agriculture's proposed and final rules to reduce the incidence of Listeria monocytogenes (Lm) in ready‐to‐ eat meat and poultry products. Using a difference‐in‐ differences approach, we find that these rules together reduced meat‐related Lm illnesses by about 60 per year, which we attribute to reductions in both the number and average size of meat‐related Lm outbreaks. We then monetize this illness reduction using an underreporting and underdiagnosis multiplier of 2.3 and an …

Genomics-Based Re-Examination Of The Taxonomy And Phylogeny Of Human And Simian Mastadenoviruses: An Evolving Whole Genomes Approach, Revealing Putative Zoonosis, Anthroponosis, And Amphizoonosis, June Kang, Ashrafali Mohamed Ismail, Shoaleh Dehghan, Jaya Rajaiya, Marc W. Allard, Haw Chuan Lim, David W. Dyer, James Chodosh, Donald Seto

United States Food and Drug Administration: Publications

With the advent of high-resolution and cost-effective genomics and bioinformatics tools and methods contributing to a large database of both human (HAdV) and simian (SAdV) adenoviruses, a genomics-based re-evaluation of their taxonomy is warranted. Interest in these particular adenoviruses is growing in part due to the applications of both in gene transfer protocols, including gene therapy and vaccines, as well in oncolytic protocols. In particular, the re-evaluation of SAdVs as appropriate vectors in humans is important as zoonosis precludes the assumption that human immune system may be na€ıve to these vectors. Additionally, as impor- tant pathogens, adenoviruses are a model …

The Impact Of The Abuse-Deterrent Reformulation Of Extended-Release T Oxycontin On Prescription Pain Reliever Misuse And Heroin Initiation, Carolyn Wolff, William N. Dowd, Mir M. Ali, Chandler Mcclellan, Angelica Meinhofer, Lukas Glos, Ryan Mutter, Matthew Rosenberg, Andreas Schikc

United States Food and Drug Administration: Publications

The introduction of abuse-deterrent OxyContin in 2010 was intended to reduce its misuse by making it more tamper resistant. However, some studies have suggested that this reformulation might have had unintended consequences, such as increases in heroin-related deaths. We used the 2005–2014 cross-sectional U.S. National Survey on Drug Use and Health to explore the impact of this reformulation on intermediate outcomes that precede heroin-related deaths for individuals with a history of OxyContin misuse. Our study sample consisted of adults who misused any prescription pain reliever prior to the reformulation of OxyContin (n = 81,400). Those who misused OxyContin prior to …

Development Of A Nicotinic Acetylcholine Receptor Nachr Α7 Binding Activity Prediction Model, Sugunadevi Sakkiah, Carmine Leggett, Bohu Pan, Wenjing Guo, Luis G. Valerio Jr., Huixiao Hong

United States Food and Drug Administration: Publications

Despite the well-known adverse health effects associated with tobacco use, addiction to nicotine found in tobacco products causes difficulty in quitting among users. Nicotinic acetylcholine receptors (nAChRs) are the physiological targets of nicotine and facilitate addiction to tobacco products. The nAChR-α7 subtype plays an important role in addiction; therefore, predicting the binding activity of tobacco constituents to nAChR-α7 is an important component for assessing addictive potential of tobacco constituents. We developed an α7 binding activity prediction model based on a large training data set of 843 chemicals with human α7 binding activity data extracted from PubChem and ChEMBL. The model …

Perivascular Macrophages In The Neonatal Macaque Brain Undergo Massive Necroptosis After Simian Immunodeficiency Virus Infection, Diana G. Bohannon, Yueying Wang, Colin H. Reinhart, Julian B. Hattler, Jiangtao Luo, Hamid R. Okhravi, Jianshui Zhang, Qingsheng Li, Marcelo J. Kuroda, Woong-Ki Kim

Nebraska Center for Virology: Faculty Publications

We previously showed that rhesus macaques neonatally infected with simian immunodeficiency virus (SIV) do not develop SIV encephalitis (SIVE) and maintain low brain viral loads despite having similar plasma viral loads compared to SIV-infected adults. We hypothesize that differences in myeloid cell populations that are the known target of SIV and HIV in the brain contribute to the lack of neonatal susceptibility to lentivirus-induced encephalitis. Using immunohistochemistry and immunofluorescence microscopy, we examined the frontal cortices from uninfected and SIV-infected infant and adult macaques (n = 8/ea) as well as adults with SIVE (n = 4) to determine differences in myeloid …

Infection Prevention In Patients Receiving Continuous Renal Replacement Therapy Through Proper Hemodialysis Line Care, Nicole Ingram, Susan Mckenna

VCU Health Nursing

The goal was to reduce Continuous Renal Replacement Therapy (CRRT)-related Central Line-Associated Bloodstream Infection (CLABSI) rates by introducing a just-in-time re-education toolkit for proper hemodialysis (HD) line care in adult Intensive Care Units (ICU).

CRRT requires specialized expertise delivered in the ICU setting with the support of HD nurses. Problem-solving when cartridges clot or clog requires ICU nurses to return the blood and notify HD to restart therapy. Current evidence supports the use of white Curos^TM caps and Tego^TM connectors when deaccessing lines in order to prevent CLABSIs, air emboli, and bleeding. A learning needs assessment revealed inconsistent …

Spirituality And Prayer On Teacher Stress And Burnout In An Italian Cohort: A Pilot, Before-After Controlled Study, Francesco Chirico, Manoj Sharma, Salvatore Zaffina, Nicola Magnavita

Walden Faculty and Staff Publications

Teaching is a stressful profession that exposes workers to the risk of burnout. Techniques involving higher mental functions, such as transcendental meditation and prayer, have been used in stress and burnout prevention programs. In this study, we report the results of an experience conducted in a group of teachers of a religious institute, in which prayer was used as a technique to prevent burnout.

Front-Line Nurse Manager Succession Planning: Building And Promoting Strong Nurse Leaders Through Implementation Of A Nurse Manager Development Program, Melany Boyd

Master of Science in Nursing Theses and Projects

Succession planning plays a pivotal role in the infrastructure of any company. Succession planning is designed to identify individuals with potential and prepare them as successors when the current leader vacates their position. With the ageing nurse population, increased role demand, and lack of interest from incoming nurses there is an increase in nurse leader (particularly nurse managers) vacancies. Through the implementation of a Nurse Manager Development Program, executives have the opportunity to strengthen the nurse manager pipeline and promote succession planning through early identification of potential leaders and placing those individuals through a 3-month program that focuses on the …

Reducing Nurses' Communication Anxiety During End Of Life Care, Susan Dunbar Wolfrom

Master of Science in Nursing Theses and Projects

End of life (EOL) conversations are meaningful discussions pertaining to the patient’s disease trajectory, symptom management, and the patient’s goals at end of life. End of life care discussions have been associated with many benefits for the patient including: decreased healthcare costs, less aggressive treatments at EOL, and a good death. These sensitive discussions must occur over the course of several interactions or spontaneously in the moment in order to support the patient during delicate moments. This makes the nurse the prime candidate to help facilitate and harbor these discussions. However, barriers to communication exist, leading to the omission of …

Students’ Knowledge Of Alzheimer’S Disease, D'Anna Helms

Nursing Theses and Capstone Projects

Preparing nursing students to care for the ever-growing aging population with memory impairment is vital. This research study aimed to determine the prevalence of knowledge of Alzheimer’s disease (AD) among Baccalaureate nursing students. A descriptive correlational design was used to determine the prevalence of AD knowledge among juniors in an Adult I course and seniors in a Mental Health nursing course. A cross-sectional design was used to collect data using the Alzheimer’s Disease Knowledge Scale (ADKS). A convenience sample of 63 student cohorts completed the survey. Results indicated that students were aware that AD is a form of dementia; however, …

How Partnerships For Community-Based Health Professions Training Were Affected By National Changes In Funding, Patricia A. Carney, Eric M. Wiser, Cynthia Taylor, Debbie Cole, Shelley Dougherty, Chris Gustaferro, Meredith Lair, Curt Stilp

Faculty Publications - College of Medical Science

Background: Area Health Education Centers (AHEC) have contributed to U.S. healthcare workforce training since 1971. National funders recently refocused efforts from K-12 students to matriculated health profession students, which reduced annual funding by $75,000 (25%) per year per Center.

Objectives: To describe how community partnership changed due to funding reductions.

Methods: Key informant interviews were conducted with all four regional center directors with community partnerships.

Lessons learned: Hosted regional centers navigated partnerships in ways that did not significantly change programs because the host institutions supported continuing the partnerships. Independent centers experienced significant changes in partnerships by ending well-established programs and …