Economic Burden And Mental Health Of Primary Caregivers Of Perinatally Hiv Infected Adolescents From Kilifi, Kenya, Patrick V. Katana, Amina Abubakar, Moses K. Nyongesa, Derrick Ssewanyana, Paul Mwangi, Charles R. Newton, Julie Jemutai

Institute for Human Development, East Africa

Background: Eighty per cent of perinatally HIV infected (PHI) adolescents live in sub-Saharan Africa (sSA), a setting also characterized by huge economic disparities. Caregiving is crucial to the management of chronic illness such as HIV/AIDS, but the economic costs and mental disorders borne by caregivers of PHI adolescents often go unnoticed. In this study, we evaluated economic costs, coping strategies and association between economic cost and mental health functioning of caregivers of perinatally HIV infected adolescents in Kilifi, Kenya.

Methods: We used a cost of illness descriptive analysis approach to determine the economic burden and Patient Health Questionnaire …

Long-Term Outcomes Of Survivors Of Neonatal Insults: A Systematic Review And Meta-Analysis, Dorcas N. Magai, Eirini Karyotaki, Agnes M. Mutua, Esther Chongwo, Carophine Nasambu, Derrick Ssewanyana, Charles R. Newton, Hans M. Koot, Amina Abubakar

Institute for Human Development, East Africa

Background: The Millennium Developmental Goals ensured a significant reduction in childhood mortality. However, this reduction simultaneously raised concerns about the long-term outcomes of survivors of early childhood insults. This systematic review focuses on the long-term neurocognitive and mental health outcomes of neonatal insults (NNI) survivors who are six years or older.

Methods: Two independent reviewers conducted a comprehensive search for empirical literature by combining index and free terms from the inception of the databases until 10th October 2019. We also searched for additional relevant literature from grey literature and using reference tracking. Studies were included if they: were …

Stretching The Law: The Application Of Public Nuisance To The Opioid Epidemic, Lindsay Manning, Hannah L. Thompson

Brigham Young University Prelaw Review

Opioid use in the United States increased five-fold in the last decade.

Every day ninety Americans die from drug abuse overdose. Is it

illegal opioid trafficking, or is it a problem within the medical profession?

Recent litigation strategies, like those used in the recent

landmark case of Oklahoma v. Johnson and Johnson, show that opioid

production and distribution are being linked to fueling the opioid

epidemic. Oklahoma is just one of the states that have concluded that

Johnson and Johnson, a large pharmaceutical company, is “overstating”

the efficiency of opioids and “understating” the harmful effects

of these drugs. Consequently, litigation …

Development And Diagnostic Application Of Monoclonal Antibodies Against Swine Acute Diarrhea Syndrome Coronavirus (Sads-Cov), Molly Kroeger

Schultz-Werth Award Papers

Swine Acute Diarrhea Syndrome Coronavirus (SADS-CoV) is a member of the Coronaviridae family. The virus is associated with severe small intestine inflammation and diarrhea in suckling piglets. In 2017, SADS-CoV was first detected and identified as the causative agent of a devasting swine disease outbreak in southern China. Routine monitoring and early detection of the source of infection is therefore integral to the prevention and control of a SADS-CoV outbreak in the United States. However, the United States does not currently have any diagnostic or surveillance tests to identify this emerging disease. To address these industry needs, we developed monoclonal …

Making Health Education Healthier: How Medical Schools Use Bias Training And Intersectional Theory To Reduce Implicit Bias, Madeleine N. Miller

Student Publications

Medical bias has been successfully characterized through two-way bias theory and the concept of the "normal body" and further divided into implicit and explicit bias. Yet, many individuals who go to the doctor are still given insufficient care because of their gender, race, class, sexuality, etc. Medical Education offers a unique opportunity for bias reduction both through formal and informal training. It is crucial that, as they are taught how to save a patient’s life, medical students are also taught to empathize with all patients and to give every patient, regardless of their gender, skin color, or class, the most …

Social Networks, The Local Food Environment, And Maternal Food Choice For Children Ages 1 To 5 Years Old In Rural Mexico, Ligia Ivette Reyes

Theses and Dissertations

Children’s nutrition is largely determined by the food choices their primary caregivers make. Food choice for children has important implications for nutrition, development, and the dietary habits and preferences that are formed during early life food exposure. Little is known about the food environments in which food choices are made and the role of social networks in maternal food choice during habit- and preference-forming years in contexts undergoing nutrition transitions and facing the double burden of malnutrition. The overall objective of this study was to gain an indepth understanding about how mothers, as primary caregivers, make food choices for their …

Addressing Transportation Barriers To Improve Appointment Attendance In Outpatient Mental Health Services, Tehut T. Tefera

Nursing Capstones

This quality improvement project aimed to reduce missed appointment rates in five outpatient mental health services through appointment reminder calls along with mitigation of transportation barriers. Studies have established the wide-ranging health and financial implications of missed appointments affecting patients and healthcare systems. During a one-month project intervention period, pre- and post-intervention missed appointment rates were compared, and providers’ sentiments were measured utilizing Likert scale questionnaires. A reduction in missed appointments by 1.1% was achieved collectively across all sites through the project duration. Additionally, provider satisfaction regarding missed appointment rates increased by 4.46%. Project cost analysis revealed that this intervention …

The Development, Implementation, And Evaluation Of A Sexual Assault Nurse Examiner Training Program, Shantee Henry

Doctor of Nursing Practice (DNP) Translational and Clinical Research Projects

Sexual assault is a growing concern in the United States. Appropriate care of its survivors is essential to controlling the short and long-term effects of this trauma. A sexual assault nurse examiner (SANE) is a registered nurse that acquires additional training specializing in the comprehensive care of sexual assault survivors. Research indicates that there are not enough SANEs to provide coverage for the increasing number of sexual assaults, especially in rural areas. To increase the number of certified SANEs in rural areas, the Health Resources and Services Administration (HRSA) of the U.S. government provided funds through a grant that was …

A High Glucose Concentration Is Well Tolerated By Colorectal Adenocarcinoma And Melanoma Cells But Toxic To Normal Human Gingival Fibroblast: Results Of An In Vitro Investigation, Muhammad Alif Mazlan, Afzan Mat Yusof, Muhammad Lokman Md Isa

Makara Journal of Health Research

Background: Glucose is associated with weight gain, which increases the risk of cancer. There is insufficient information on the effects of high glucose concentrations on cell lines. This study evaluated the viability patterns of human cancer and normal cell lines treated with glucose.

Methods: Human gingival fibroblast (hGF), colorectal adenocarcinoma (HT29), and skin malignant melanoma (A375) cell lines were cultured and treated with additional glucose in three respective concentrations: 1 mg/ml, 5 mg/ml, and 10 mg/ml. Then, cell viability was measured using an MTT(3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide)-assay. The data were analyzed using the Statistical Package for the Social Sciences …

The Domestic And Global Implications Of Considering Non-Us Origin A Risk Factor For Tuberculosis In The United States, Emma Gile 20

Honor Scholar Theses

No abstract provided.

Cyber Security In The Healthcare Industry, Giovanni Ordonez 20

Honor Scholar Theses

No abstract provided.

Children’S Autonomy And Medical Decision Making, Haley Thompson 20

Honor Scholar Theses

No abstract provided.

Not A Magic Pill: An Educational Model On Antibiotic Prescribing, Christina Rose Leonard

Nursing Capstones

Background: Inappropriate antibiotic prescribing is common in outpatient settings across the United States. The Centers for Disease Control and Prevention has found in studies that nearly 1 in 3 antibiotics prescribed at outpatient facilities is unnecessary. The misuse and overuse of antibiotics is accelerating the process of antibiotic resistance, as well as causing an increase in adverse events, including death. The literature indicates that knowledge plays a major factor in overprescribing, as well as provider attitude and patient expectations.

Objective: Present clinical practice guidelines to providers within a rural family practice clinic setting aimed at improving antibiotic prescribing. Gather information …

Working From Home During The Covid-19 Pandemic: Tips And Strategies To Maintain Productivity & Connectedness, Ian A. Lane

Faculty Publications (Peer-Reviewed)

No abstract provided.

Utilization Of A Concurrent Query Form To Improve Clinical Documentation In A Va Facility For Patients With Stroke Or Tia, Lisa A. Keefner

Electronic Theses and Dissertations

Caring for stroke patients diagnosed with acute ischemic stroke (AIS) and transient ischemic attack (TIA) at Veterans Health Administration (VHA) acute care hospitals is a very complex process that centers on accurate documentation. Inaccurate or missing documentation leads to patient safety issues, lower quality care, and inaccurate Veteran Equitable Resource Allocation (VERA) classification for reimbursement. This pilot project’s 3 problems of interest include improving provider response to clinical queries about documentation, capturing national metrics collected by the VHA, and accurately representing veterans in VERA classification. Based on a review of the literature available on patient treatment file (PTF) accuracy and …

Promoting Health, Justice And Well-Being Of Minnesota's Lgbtq+ Community: Banning Conversion Therapy, Katelin Farmer, Ashley Hansen, Chelesa Schweim, Sarah Petersen

Master of Social Work Student Policy Advocacy Briefs

There are 853 cities in Minnesota, and only two have enacted protections for LGBTQ+ people from the harmful practice of conversion therapy. All Minnesotans deserve access to safe, ethical, affirming, and evidence-based mental health care.

Stunting And Infectious Disease In Ethiopian And Zambian Children, Alyssa Arndt

NUTR/GLST 498b: Global Research Experiences in Nutrition and Health

PURPOSE: To evaluate whether children who are malnourished/stunted are more likely to have experienced infectious disease.

METHODS: 6th and 7th students (n=546) were interviewed about health history and assessed using anthropometry.

RESULTS: Children who are short for their age also have higher rates of stunting. Malaria is the most experienced infectious disease.

CONCLUSIONS: Given that malaria was the most common infectious disease experience listed among middle school children, and that those who have experienced disease are more likely to be stunted, increased malaria prevention methods may improve the long-term health of Ethiopian and Zambian schoolchildren.

Allowing Entry Of Foreign Health Professionals In Containing The Covid-19 Pandemic In The Philippines, Tereso S. Tullao, John Paolo R. Rivera, Cynthia P. Cudia

Angelo King Institute for Economic and Business Studies (AKI)

In light of the risks posed by COVID-19 on Filipino health care professionals, this Angelo King Institute of Economic and Business Studies policy brief recommends short-term solutions that may support in containing the outbreak and at the same time mitigate the risks. Authored by Dr. Tereso Tullao, Jr., John Paolo Rivera, and Dr. Cynthia Caudia

Health Care And Plains Native Americans: Striving Towards A Culturally Competent Medical School Curriculum, Benjamin M. Jacobs

Honors Thesis

My honors thesis will explore the curriculum at the USD Sanford School of Medicine (SSOM). I plan to examine the curriculum for cultural competence and diversity education, specifically on Native (American Indian/Alaskan Native) peoples. My primary goal is to increase the educational importance the Sanford School of Medicine places on the culture of all groups, especially, Native peoples. My topic is important because diversity and inclusion are essential parts to creating a unified team. Furthermore, this topic is especially relevant here in South Dakota due to the number of Native peoples in the state. South Dakota has the fourth highest …

Time For A Change? Brain Activity And Behavioral Performance Reveal Different Dynamics At Short, Intermediate, And Long Delay Intervals During A Delay Discounting Task, Conrad A. Mohr-Eymer

Honors Thesis

In our day to day lives, the ability to make goal-oriented decisions plays a crucial role in both our work and social lives. Therefore, researchers have examined how factors such as a varying reward or delay may affect decision making. One’s performance when making intertemporal choices, decisions made between a smaller and sooner (SS) reward and a larger and later (LL) reward, are often examined to study these factors. Although time and reward magnitude are important dimensions when individuals make decisions during delay discounting, little is known about the relationship between time perception, reward magnitude, and underlying neural mechanisms. To …

Sex, Stress, And Prefrontal Cortex: Influence Of Biological Sex On Stress-Promoted Cocaine Seeking, Elizabeth M. Doncheck, Gage T. Liddiard, Chaz D. Konrath, Xiaojie Liu, Laikang Yu, Luke A. Urbanik, Matthew R. Herbst, Margot C. Debaker, Nicholas J. Raddatz, Erik C. Van Newenhizen, Jacob Mathy, Marieke R. Gilmartin, Qing-Song Liu, Cecilia J. Hillard, John Mantsch

Biomedical Sciences Faculty Research and Publications

Clinical reports suggest that females diagnosed with substance use disorder experience enhanced relapse vulnerability compared with males, particularly during stress. We previously demonstrated that a stressor (footshock) can potentiate cocaine seeking in male rats via glucocorticoid-dependent cannabinoid type-1 receptor (CB1R)-mediated actions in the prelimbic prefrontal cortex (PrL-PFC). Here, we investigated the influence of biological sex on stress-potentiated cocaine seeking. Despite comparable self-administration and extinction, females displayed a lower threshold for cocaine-primed reinstatement than males. Unlike males, footshock, tested across a range of intensities, failed to potentiate cocaine-primed reinstatement in females. However, restraint potentiated reinstatement in both sexes. While sex differences …

Phonological Awareness In Deaf/Hard Of Hearing Children, Cindy Stetler

Honors Projects

Children who are deaf or hard of hearing (DHH) in America may learn American Sign Language (ASL) or English as their first language and may early-on or eventually be bilingual in ASL and English. In school, however, they will need to learn how to read English since ASL does not have a written system. An aspect of reading that can be particularly difficult for children who are DHH is phonological awareness (PA). Something that seems to be missing from the literature is looking at the relation between sign PA, spoken PA, and reading literacy in ASL and English. This will …

Compliance Of Hand Written Transfusion Requisition Form And Improvement After Online Request - A Clinical Audit, Nadia Nasir, Mohammad Usman Shaikh, Natasha Ali, Shabneez Hussain

Department of Pathology and Laboratory Medicine

Objective: To assess the compliance of healthcare personnel with regard to sending completely filled transfusion requisition forms.
Methods: The audit was conducted at Aga Khan University Hospital, Karachi, and comprised requisition slips received at the hospital blood bank from September 2014 to February 2015. The British Committee for Standards in Haematology guidelines was used as the standard. Percentage of each variable on the proforma was analsyed. Rating Results: The audit and the re-audit both comprised 1000 transfusion requisition forms each. In the audit, The sum of total scores of all the transfusion requisition forms was 4911, indicating a compliance rate …

The Public Health Dialogue, 2020 (Editor's Choice), Alfredo Morabia

Publications and Research

No abstract provided.

Lower Limb Force Asymmetries During Landing And Jumping Exercises, Simon Cone

Masters Theses

Significant asymmetries can exist between the lower limbs’ force production during the take-off phase of bilateral jumping exercises. Some studies have indicated that similar asymmetries can exist during the landing phase as well. It has not been demonstrated if the magnitude and/or direction of this imbalance is alike during the landing (L) and take-off (TO) phase of a jumping exercises. The main purpose of this study was to determine if there is a difference in the asymmetry that occurs during the L and TO phases. In order to quantify the degree and describe the direction (left. vs. right) of the …

A Survey Of Patients With Congenital Orthopedic Conditions In Malawi: Factors That Influence Late Presentation, Brianna Wallis

Undergraduate Honors Thesis Projects

Staff at CURE International, a non-profit organization that provides orthopedic care in Malawi, noticed a high prevalence of patients with congenital orthopedic conditions who are presenting late for treatment. Late presentation results in prolonged pain or discomfort for the patient and has the potential for increased cost to the institution, longer duration of treatment, and decreased quality of outcomes. To identify the factors that influenced presentation delays, we surveyed the caregivers of patients with congenital conditions that were seen in out-patient clinics, in-patient wards, and mobile clinics across the country. Sixty-two caregivers were surveyed; forty-two patients had a diagnosis of …

Primates On The Farm – Spatial Patterns Of Human–Wildlife Conflict In Forest-Agricultural Landscape Mosaic In Taita Hills, Kenya, Mika Siljander, Toini Kuronen, Tino Johansson, Martha Nzisa Munyao, Petri K.E. Pellikka

All Peer-Reviewed Publications

Human–wildlife conflict (HWC) is a growing concern for local communities living in the vicinity of protected areas. These conflicts commonly take place as attack by wild animals and crop-raiding events, among other forms. We studied crop-raiding patterns by non-human primates in forest–agricultural landscape mosaic in the Taita Hills, southeast Kenya. The study applies both qualitative and quantitative methods. Semi-structured questionnaire was used in the primary data collection from the households, and statistical tests were performed. We used applied geospatial methods to reveal spatial patterns of crop-raiding by primates and preventive actions by farmers. The results indicate most of the farms …

A Holistic Exploration Of Fatigue Experienced By Women Before A Myocardial Infarction, John R. Blakeman, Wendy M. Woith, Kim S. Astroth, Sheryl H. Jenkins, Stephen J. Stapleton

Faculty Publications - Mennonite College of Nursing

Most women report fatigue in the weeks and months leading to a myocardial infarction (MI). However, fatigue is a complex phenomenon. Dimensions of this MI related fatigue, such as timing, distress, intensity, quality, patterns, and associated characteristics have not been established through focused study of this symptom. A lack of a holistic understanding of this symptom makes clinical decision making difficult, given that fatigue is a frequently reported symptom overall.

Avoiding Common Weight Gain In Kidney Transplant Recipients Via An Activity Program, Uchenna Egbosimba

The Eleanor Mann School of Nursing DNP Capstone Projects

Kidney transplant recipients have shown to have substantial post-transplant weight gain within their first year after transplantation (Henggeler, C. K., Plank, L. D., Ryan, K. J., Gilchrist, E. L., Casas, J. M., Lloyd, L. E., Collins, M. G., 2018). After the development of end stage renal disease, a reduction in physical activity can occur as well as postoperative recovery stress (van Adrichem et al., 2018). Evidence has shown that increasing physical activity post-transplantation has various beneficial effects on the metabolic profile, body composition, and quality of life of kidney transplant recipients (Chan et al., 2019). A home-based exercise walking program …

Impacts On Fitness Associated With Acquisition Of Gut Microbiota In Drosophila, Corinne Topolski

Honors Projects

Drosophila melanogaster is a model organism that has been studied to demonstrate the role of gut microbiota in fitness. It has already been established the gut microbiota is extremely important for the health of the organism, but the source of the microbiota has not been studied as thoroughly. In order to test if the source of microbiota affects the fitness of the individual, adult male and female flies were placed onto plates to defecate after being raised on standard food and food with carbenicillin. Stock eggs were washed in either water or a bleach solution, then placed on the defecation …