Medicine and Health Sciences Commons^™

Procedural Justice And Body Worn Cameras, Yael Granot

Psychology: Faculty Publications

The extensive and rapid roll out of body cameras across American police forces in the past decades was intended to improve issues of accountability and transparency in policing. Trust and perceptions of fairness of police are shaped, in large part, by how one is treated by officers and departments—the fundamental interpersonal work of procedural justice. This Article reviews findings on public and police support for body cameras, as well as research connecting body cameras to perceptions of procedural justice. It then elaborates on past research with a vignette experiment, aimed at isolating the unique and interactive effects of just policies, …

Thoracolumbar Fractures: Historical Systems And Advancements With The Ao Spine Classification, Barry Ting Sheen Kweh, Alex R. Vaccaro, Gregory D. Schroeder, Jose A. Canseco, Maximilian Reinhold, Mohamed M. Aly, Sebastian Bigdon, Mohammad El-Skarkawi, Richard J. Bransford, Andrei Fernandes Joaquim, Harvinder Singh Chhabra, Emiliano Vialle, Rishi M. Kanna, Charlotte Dandurand, Cumhur Öner, Jin Wee Tee

Rothman Institute Papers

Study Design: Systematic Review. Objective: To describe the historical classifications of thoracolumbar injuries and their evolution into the AO Spine Thoracolumbar Injury Classification System. Methods: A systematic review of MEDLINE, EMBASE and Cochrane Databases was performed in keeping with Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines. Results: 445 articles were crystallized to 14 included studies. Simple categorization systems offered by Bohler or Watson-Jones merely identify fracture morphology. Holdsworth and Denis conveyed a sense of the stability of injuries by noting columns of stability, but still failed to take into consideration important factors such as neurological status or …

Exploring Parents’ Perspective Of Outdoor Occupational Therapy Sessions, Harold Ho, Michelle Huynh, Christina Le, Amy Morrison

Master's Projects

Introduction: Outdoor play is recognized as critical for supporting children’s development across physical, cognitive, and social-emotional domains (Firby & Raine, 2022; Walker & Ray, 2024; Zhu et al., 2024). The current literature suggests that outdoor play strengthens executive functioning, early learning skills, and enhances social-emotional competency (Dinkel et al., 2019; Walker & Ray, 2024; Zhu et al., 2024). Furthermore, accessibility to outdoor play is shaped by contextual factors, including parental perceptions of safety, environmental barriers, and broader societal influences (Cox et al., 2025; Faulkner et al., 2025; Jelleyman et al., 2019). The research suggests that common parental concerns have emerged …

Histopathological Effects Of The Intrathecal Chondroitinase Abc Administration In Spinal Cord Injured Rats: A Systematic Review, Mohammad Amin Habibi, Ali Anjomshoa, Mohsen Sadeghi-Naini, Zahra Ghodsi, Samuel Berchi Kankam, Erfan Razavi, Armin Aryannejad, Seyed Mohammad Piri, Akam Ramezani, Rasha Atlasi, Kawthar Mohamed, Sina Shoo, Meysam Kaveh, Akbar Fotouhi, Arman Zeinaddini, James S. Harrop, Alex R. Vaccaro, Michael G. Fehlings, Vafa Rahimi-Movaghar

Department of Orthopaedic Surgery Faculty Papers

Introduction: Chondroitinase ABC (ChABC) has been considered a potential treatment for spinal cord injury (SCI). We aim to identify and evaluate the histopathological effects of intrathecal ChABC administration in SCI rat models.

Methods: We searched PubMed/MEDLINE, Scopus, Web of Science, Embase, and Cochrane Library for studies published from the inception of each database until November 22, 2022.

Results: Of 3857 screened citations, 17 studies met eligibility criteria and were entered into the qualitative analysis. Sixteen studies were of high quality, and one study was of medium quality. The four main rat strains used in studies were Sprague-Dawley, Wistar, Lister hooded, …

Surgery And The Role Of Biologics In Chronic Rhinosinusitis With Nasal Polyps: A Narrative Review, Claire Hopkins, Wytske J. Fokkens, Joseph K. Han, Shigeharu Fujieda, Osama Marglani, Scott Nash, Mark Corbett, Amr Radwan, Yamo Deniz, Paul Rowe, Richard J. Harvey

Department of Otolaryngology (ENT) Faculty Publications

Background

Biologic treatments have helped progress the management of severe chronic rhinosinusitis with nasal polyps (CRSwNP) by targeting the mediators and effectors underlying chronic type 2 inflammation. This review considers the impact of biologics on endoscopic sinus surgery (ESS) in CRSwNP.

Methods

We conducted a comprehensive literature search through March 31, 2025.

Results

ESS as part of holistic management with topical anti-inflammatory treatment is very effective at improving symptoms and quality of life in patients with severe CRSwNP. The criteria for eligibility for surgery are not standardized and there is wide variation in surgery rates between regions. Despite regular post-operative …

Coordinated Regulation Of Capping Protein By Carmil And V-1/Myotrophin, John A Hammer, John A Cooper

2020-Current year OA Pubs

Capping Protein (CP) plays a central role in controlling actin filament dynamics in almost all eukaryotic cell types by virtue of its ability to block monomer addition and loss at the barbed end of the actin filament. Like other proteins that control actin assembly, CP is subject to regulation. Here we focus on two direct regulators of CP-CARMIL and V-1/Myotrophin. Specifically, we review recent biochemical, structural, imaging, and cell biological data that argue these two proteins cooperate to create a regulatory cycle for CP that controls its availability, activity, and site of action in the cell. Finally, we discuss unresolved …

Revisiting Nasal Polyp Scoring In Clinical Trials: Interpretive Variability And The Need For Standardization, Leigh J. Sowerby, Babak Pourmomenarabi, Antonino Maniaci, Olivia Ginty, Joseph Khristian Han

Department of Otolaryngology (ENT) Faculty Publications

[Introduction] Borish et al. provided an excellent review highlighting methodological variability among the six pivotal Phase III trials [1]. One critical yet overlooked issue is the inconsistent application of the endoscopic nasal polyp score (NPS), a primary outcome measure in all trials.

Oropharyngeal Syphilis Presenting As Tongue Based Ulcer With Lymphadenopathy, Serena F. Pu, Kevin J. Carlson, Jonathan R. Mark, Benjamin J. Rubinstein

Department of Otolaryngology (ENT) Faculty Publications

Within the aerodigestive tract, syphilis presents with varied signs and symptoms, some of which may mimic malignancy or other disease processes. We present the case of a 29-year-old man with otalgia and odynophagia who was found on physical examination and office laryngoscopy to have a 4-cm ulcerative mass of the tongue base and cervical lymphadenopathy. While planning for tissue diagnosis, the patient’s serologies revealed positive treponemal antibody testing and elevated rapid plasma reagin (RPR) titers, confirming syphilitic infection, likely representing secondary syphilis. While awaiting operative biopsy, the patient received intramuscular penicillin with complete resolution of the mass and symptoms, and …

Occupational Human Papillomavirus Exposure Risks For Laryngeal Surgeons And Phoniatricians: A Joint European Laryngological Society (Els) And Union Of European Phoniatricians (Uep) Delphi Clinical Consensus Statement, Shiying Hey, Alberto Maria Saibene, Milan Amin, Jennifer Anderson, Christoph Arens, Simon Best, Guillermo Campos, Craig Derkay, Gauthier Desuter, Frederik G. Dikkers, Isabel Garcia-Lopez, Ahmed Geneid, Anastasios Hantzakos, Markus Hess, Yakubu Karagama, Marina Mat Baki, Napur Kapoor Nerurkar, Daniel Novakovic, Haldun Oguz, Shazia Peer, Jasmine Prasad, Carlo Robotti, David Vokes, Chi-Te Wang, Malgorzata Wierzbicka, Michal Zabrodsky, Nicolien Van Der Poel

Department of Otolaryngology (ENT) Faculty Publications

Purpose

Laser surgical management of human papillomavirus (HPV)-related disease, such as recurrent respiratory papillomatosis (RRP), in the upper aerodigestive tract generates surgical smoke, which may represent a source of occupational viral exposure for laryngeal surgeons, phoniatricians, anesthesia providers and scrub nurses. Despite growing awareness, protective measures remain inconsistently implemented. This study aimed to develop an evidence-informed clinical consensus statement (CCS) to guide occupational HPV risk management in laryngology.

Methods

A modified Delphi consensus process was conducted under the auspices of the European Laryngological Society (ELS) and the Union of the European Phoniatricians (UEP). A panel of 26 international experts undertook …

Mepolizumab Improves Outcomes In Patients With Crswnp With One Or More Prior Nasal Polyp Surgeries, Joseph K. Han, Joaquim Mullol, Martin Wagenmann, Laura Walrave, Lingjiao Zhang, Ana R. Sousa, Peter Howarth, Claire Hopkins

Department of Otolaryngology (ENT) Faculty Publications

BACKGROUND: Patients with chronic rhinosinusitis with nasal polyps (CRSwNP) often undergo multiple nasal surgeries. The Phase III SYNAPSE study (GSK ID:205687; NCT0308579) demonstrated that mepolizumab reduces the need for repeat surgery. We explored whether outcomes differed based on the number of prior surgeries. METHODOLOGY: This post hoc analysis of SYNAPSE stratified patients by history of 1 or more than 1 prior surgery. Patients were randomised to receive mepolizumab or placebo every 4 weeks, alongside standard of care, for 52 weeks. Outcomes included change from baseline in endoscopic nasal polyp (NP) score, visual analogue scale (VAS) scores for nasal obstruction, loss …

Dupilumab For Patients With Allergic Fungal Rhinosinusitis, Amber U. Luong, Joshua M. Levy, Sarah K. Wise, Joseph K. Han, Mamoru Yoshikawa, Luo Zhang, Rodney Schlosser, Prerna Ranganathan, Paula Dakin, Jennifer Maloney, George D. Yancopoulos, Andrew P. Fontenot, Neelam A. Phadke, Lacey R. Robinson

Department of Otolaryngology (ENT) Faculty Publications

Background

Allergic fungal rhinosinusitis (AFRS) is a severe subtype of chronic rhinosinusitis characterized by fungal hypersensitivity and accentuated type 2 inflammation. Dupilumab-a fully human monoclonal antibody blocking interleukin-4/13, approved for type 2 inflammatory diseases, including chronic rhinosinusitis with nasal polyps-may benefit patients with AFRS.

Objective

We sought to understand the effect of dupilumab in AFRS

Methods

In this phase 3 trial, patients with AFRS aged ≥6 years were randomized to dupilumab or matched placebo for 52 weeks. The primary end point was Lund-Mackay computed tomography (LMK-CT) score, quantifying sinus opacification, at 52 weeks. Secondary end points were multiplicity-controlled and hierarchically …

Ancestry-Dependent Immunologic And Prognostic Effects Characterize The Prostate Cancer Urinary Proteome, Annie Ha, Jaron Arbet, Zhuyu Qiu, Amanda Khoo, Brian P. Main, Meinusha Govindarajan, Matthew Waas, Stanley K. Liu, O. John Semmes, Julius O. Nyalwidhe, Paul C. Boutros, Thomas Kislinger

Leroy T. Canoles Jr. Cancer Research Center Faculty Publications

Urine is an attractive biomarker analyte for non-invasive longitudinal monitoring of health and disease, particularly for diseases of the genitourinary tract, like prostate and bladder cancer. The composition of an individual's urine reflects both genetic and lifestyle characteristics that differ across geographies and populations, like diet, hydration and other socio-economic factors. While men of African ancestry have elevated prostate cancer risk, it is unclear to what extent this influences urinary biomarkers. We therefore quantified the urinary proteomes of 329 localized prostate cancer patients: 135 self-identifying as White and 194 self-identifying as Black. We identified 110 proteins that significantly differed between …

Startle Habituation And Vagally Mediated Heart Rate Variability Influence The Use Of Emotion Regulation Strategies, Xiao Yang, Fang Fang, Angela Ximena Babb

Psychology Faculty Publications

Emotion regulation refers to the processes through which people modulate their emotional experiences and expressions, and difficulties in these processes underpin many forms of psychopathology. According to the process model, emotion regulation encompasses five classes of strategies, commonly grouped into antecedent-focused strategies (e.g., cognitive reappraisal) and response-focused strategies (e.g., expressive suppression). These strategies involve both explicit and implicit processes, which can be objectively assessed using physiological indices. The present study examined the effects of startle habituation and vagally mediated heart rate variability (vmHRV) on the use of cognitive appraisal and suppression. Forty-nine college-aged participants were recruited, and their resting heart …

Gaze Transition Entropy And Automation Trust In Multitasking Workspace, Yusuke Yamani, Austin Jackson, Tetsuya Sato, Feyishola Ashimi, Michael S. Politowicz, Eric T. Chancey, Makoto Itoh

Psychology Faculty Publications

Safe flight operation requires visual scanning across multiple displays in a cockpit, which collectively represent the state of the aircraft and supporting automation. Trust is a crucial factor that drives human-automation interaction, and recent work has suggested a relationship between an operator's visual attention and automation trust. One index that captures predictability of eye movements between different areas of interest is gaze transition entropy. The current work reanalyzed data from Sato et al., which examined eye movement patterns and trust in automation associated with the system monitoring task of the Multi-Attribute Task Battery. Results showed credible positive correlations between the …

I Can't Stop: The Effects Of Psychological Climate For Overwork On Recovery Experiences, Jeffrey Drake Terry, Konstantin P. Cigularov

Psychology Faculty Publications

Recovery experiences are important for many health and well-being outcomes. One potential threat to an individual's recovery experiences in the workplace is psychological climate for overwork. The purpose of the present study was to examine the relationship between psychological climate for overwork and recovery experiences. Using a multi-wave research design (N = 202), we found that psychological climate for overwork had direct effects on psychological detachment and indirect effects on psychological detachment and relaxation through cognitive workaholism and work-recovery guilt. These results suggest that psychological climate for overwork may contribute to an individual's experience of cognitive workaholism and work-recovery guilt, …

Cross-National Longitudinal Insights Into College Alcohol Beliefs And Consequences: The Role Of Food And Alcohol Disturbance, Javiera A. Hernandez Puelma, Katherine A. Berry, Luke Herchenroeder, Alison Looby, Adrian J. Bravo, Christopher C. Conway, Fermín Fernández-Calderón, James M. Henson, Lee Horgarth, Manuel I. Ibáñez, Debra Kaminer, Matthew Keough, Oleg Medvedev, Laura Mezquita, Yanina Michelini, Generós Ortet, Ricardo Pautassi, Matthew R. Pearson, Angelina Pilatti, Mark A. Prince, Jennifer P. Read, Verónica Vidal Arenas, Cross-Cultural Addictions Study Team

Psychology Faculty Publications

The present study examined the mediational role of FAD-intoxication (i.e., restricting calories to increase or quicken alcohol intoxication) in the relationship between college alcohol beliefs (CABs) and negative alcohol-related consequences. A sample of 2543 student drinkers from six countries completed the baseline survey, and 505 drinkers completed at least one follow-up. Two models examined whether frequency of FAD-intoxication mediated the relationship between CABs and alcohol-related problems, and structural invariance testing was conducted across sex and countries. FAD-intoxication was concurrently and prospectively associated with greater endorsement of alcohol-related consequences and significantly mediated the effects of CABs on alcohol-related consequences. The relationship …

From Molecules To Minds: Integrative Multi-Omics In Psychiatry, Hossein Abbasi, Sage E. Hawn, Arash Javanbakht, Soraya Seedat, Kyle Bourassa, Sinead M. Sinnott, Antonia V. Seligowski, Sian Hemmings, Nathan A. Kimbrel, Alicia K. Smith, Leslie Brick, Divya Mehta

Psychology Faculty Publications

Psychiatric disorders are biologically complex conditions arising from interactions across genomic, epigenomic, transcriptomic, proteomic, metabolomic, and metagenomic layers. Single-omics approaches rarely capture more than a fraction of the variance in complex conditions, underscoring the importance of integrative multi-omics frameworks. This mini-review summarizes key methodologies and their application in psychiatric research, with a focus on systems-level integration of genomic risk scores, transcriptomic networks, and neuroimaging data to advance biological understanding of disorders such as depression, schizophrenia, and Alzheimer’s disease. We also outline the infrastructural requirements for effective multi-omics research, including standardized biobanking, Laboratory Information Management Systems, adherence to FAIR data principles, …

Early Parenting Stress And Later Abuse Risk: Dyadic Analysis Of Mediation By Maternal And Paternal Negative Attributions, Jewelian N. Fairchild, Christina M. Rodriguez

Psychology Faculty Publications

Predicting the likelihood parents will become physically abusive towards their children remains a high priority. Early parenting stress may increase the extent to which parents negatively appraise their children's behaviours, which in turn may influence their abuse risk. This study explored whether parental negative attributions mediated the association between early parenting stress and later abuse risk. A sample of 186 first-time mothers and 146 of their male partners reported on their parenting stress when infants were 6 months old and their negative attributions regarding child behaviours at 18 months. Parents' child abuse risk was assessed at age four using two …

Reward Deficits In Co-Occurring Social Anxiety And Depression: The Roles Of Anhedonia, Boredom, Loneliness, And Covid-19 Social Restriction, Nathan M. Hager, Alicia L. Milam, Hannah C. Hamrick, Benjamin Swanson, Matt R. Judah

Psychology Faculty Publications

Prior research points toward reward deficits as crucial to the link between social anxiety disorder and major depressive disorder. However, studies have not explored specific types of reward deficits or how social-environmental factors may impact them. The current study examined whether the indirect effects of three reward deficits (anhedonia, boredom, and loneliness) accounted for the connection between social anxiety and depression. Questionnaires were collected in a sample of college students (N = 523) during the first year of the COVID-19 pandemic, allowing examination of environmental stressors (i.e., remote learning and current friend network size) on reward deficits. Indirect effect models …

Best Practices For Using Biological Data In Psychological Research, Sage E. Hawn, Sinead M. Sinnott, Alicia K. Smith, Kyle Bourassa, Leslie Brick, Sian Hemmings, Soraya Seedat, Arash Javanbakht, Lauren Smith, Antonia V. Seligowski, Nathan A. Kimbrel, Divya Mehta, Hossein Abbasi, Erika Wolf

Psychology Faculty Publications

Advances in statistical techniques for analyzing biological data have driven the need for larger sample sizes, which are ultimately made possible through team science efforts. Findings from these efforts have led to a significant shift in approaches to biological data collection over the past decade, from traditional approaches relying on single measures or assays collected by individual investigators in small lab-based studies to high-dimensional methodologies embedded within large cohorts or multi-site studies. These recent large scale consortium efforts necessitate careful consideration across the full data pipeline, from pre-data generation and sample collection to processing and statistical analysis, while addressing challenges …

A Real-Time Examination And Comparison Of Differentiation Among Suicidal Thinking And Affect Items In An Adolescent Sample, Elizabeth A. Edershile, Kinjal K. Patel, Annabelle M. Mournet, Richard T. Liu, Catherine R. Glenn, Evan M. Kleiman

Psychology Faculty Publications

Suicide risk assessments require individuals to differentiate among types of suicidal thoughts (e.g., passive vs. active); yet most research relies on aggregate metrics that obscure this differentiation. Indeed, more severe forms of suicidal thinking are thought to involve the simultaneous experience of multiple forms of thoughts at high intensities. The present study draws on concepts from the affect differentiation literature to (a) examine different ways to operationalize differentiation in suicidal thinking and (b) compare differentiation in suicidal thinking with differentiation in affect. Adolescents (N = 200) recently hospitalized for suicidal thoughts and behaviors completed a 28-day ecological momentary assessment …

Metabolic Profiles Distinguish Normal And Malignant Breast Tissues In African American Women, Delisha A. Stewart, Lance Buckley, Wimal W. Pathmasiri, Susan L. Mcritchie, Tammey J. Naab, Robert L. Dewitty, Kelly Bolden, Estelle Cooke-Sampson, Desta A. Beyene, Vikisha T. Fripp, Luisel Ricks-Santi, Robert L. Copeland, Jr., Susan J. Sumner, Yasmine M. Kanaan

Department of Biomedical and Translational Sciences Faculty Publications

Background: Breast cancer (BCa) is the most common malignancy in women where incidence, distribution, clinical outcomes, and mortality rates vary widely among women of different racial and/or ethnic backgrounds.
 
Methods: To explore the metabolome of normal and malignant breast tissues and try to discriminate BCa disease in a cohort of African American women, biospecimens (n=48) were analyzed by untargeted metabolomics using 1H nuclear magnetic resonance (NMR) spectroscopy. Breast specimens were characterized as control or malignant. Control samples were obtained from reduction mammoplasty surgeries, including those with benign fibrocystic changes or non-malignant fibroadenoma, whereas malignant BCa samples encompassed grades I-III and …

The Role Of Mscs In The Il23/17 Pathway And Their Response To Mechanical Stress, Norma Aileen Dominguez Jimenez

Honors Theses

Mechanical stress plays a central role in shaping cellular behavior within skeletal tissues. At the enthesis, where tendons and ligaments attach to bone, repeated mechanical loading is strongly associated with inflammation and the development of ankylosing spondylitis (AS). Although mesenchymal stem cells (MSCs) are known to contribute to tissue structure and repair at these sites, their potential role in inflammatory signaling, particularly within the I 23/IL 17 pathway, remains unclear. In this thesis I investigated whether MSCs are capable of expressing cytokines involved in this pathway and how mechanical stress and differentiation influence this expression. Using the mouse derived C3H/10T1/2 …

"It's A Dance": Examining Midwives As Choreographers Of Reproduction In Maine, Annie Goldstein

Honors Theses

This thesis examines the contemporary work of community-based Maine midwives through the theoretical framework of choreography. In the context of this work, choreography can be understood as the well-thought-out, purposeful undertaking of a process during which negotiation, coordination, and improvisation are required to adapt to constantly changing circumstances. Using choreography, this thesis attempts to understand how Maine midwives navigate global market processes and practice under authoritative forms of biomedicine, ultimately linking them to other midwives across various global sites. Situated within Maine’s maternal health landscape that is characterized by the ongoing closure of labor and delivery units and rural hospitals, …

Emotionally Healthy Black Men: Guidelines For Supporting Mental Health Treatment For Black Men In Ohio, Eira Nichell Yates

Antioch University Dissertations & Theses

This study examines the barriers that prevent Black men in Ohio from seeking treatment for depression and other mental health conditions and explores strategies to improve engagement and outcomes. Although depression is the most prevalent mental health disorder in the United States, it remains underdiagnosed and undertreated among Black men, contributing to persistent mental health disparities. The limited body of research addressing help-seeking behaviors within this population necessitated the use of a Delphi methodology to obtain expert consensus on key challenges and promising practices. A panel of subject-matter experts in mental health, social services, and culturally responsive care participated in …

The Use Of Mindfulness In Empirically Supported Treatments In Psychology, Timothy Stewart

Antioch University Dissertations & Theses

After gaining popularity in the United States of America (USA) in the 1960s and 1970s, Buddhist mindfulness was introduced to clinical psychology and investigated for its potential psychological healing effects. In the years since, mindfulness has been widely used in empirically supported treatments (ESTs) in clinical psychology in the USA to treat a wide variety of psychological conditions and disorders. This dissertation examines and compares conceptualizations and implicit understandings of mindfulness in early (Theravāda) Buddhism and in ESTs in clinical psychology in the USA. Through textual narrative analysis of two Buddhist sutta and 10 clinical psychology journal articles, this study …

Bi+ Cismale Experiences With Straight Cismale Friends, Taylor M. Hardock

Antioch University Dissertations & Theses

Minority Stress Theory (2006) posits that individuals with a marginalized sexual identity have unique challenges and stressors. Bisexual+, or bi+, individuals have particular stressors related to not holding a monosexual identity, including specific mental health challenges. Research has shown that friendship can have many positive benefits on individuals, though the literature looking at friendship among bi+ identifying people is very limited. This qualitative study investigates the experiences of friendship between bi+ and straight cis men, especially as they may relate to minority stress and experiences of resilience and community belongingness. A thematic analysis was utilized to understand the personal experiences …

Cross-Domain Identity Development In Bipoc Autistic Adults: A Grounded Theory Study, Ginnylyne Mariano Guisadio

Antioch University Dissertations & Theses

Racial and autistic identity development both involve navigating stigma, seeking community, and contending with dominant frameworks that constrain authentic self-expression, yet existing research has not examined how these processes interact for individuals holding both identities. These interactions unfold within structural conditions such as diagnostic disparities, culturally specific ableism, and racialized consequences of visible autistic expression, which shape how identity development proceeds for BIPOC autistic adults. This study investigated whether and how the core identity processes of exploration and commitment proceeded for this population. Nine BIPOC autistic adults participated in written interviews analyzed through constructivist grounded theory, with identity status theory …

Stability Of Salivary Microrna Measures Across An Ncaa Division I Football Season: Implications For Microrna As A Biomarker Of Concussion, Thomas R. Campbell, Martina Zamponi, Delaney Leathers, Julie Cavallario, Jessica C. Martinez, Peter A. Mollica

Rehabilitation Sciences Faculty Publications

Background

Clinicians often face challenges in concussion care due to a heavy reliance on subjective patient input. Recently, research has sought objective biomarkers, like salivary microRNAs, to improve concussion management. However, significant limitations hinder the use of microRNAs as a diagnostic tool, including the cumulative effects of a contact sport season. A better understanding of the response to a contact sport season would help researchers and clinicians interpret expression changes at the time of injury in the context of seasonal variation. in Therefore, this study investigated the reliability of previously identified salivary microRNA targets across one contact sport season.

Methods …

Prevalence And Correlates Of Anxiety And Depression Symptoms Among Medical Students: The Role Of Student Debt Burden, Foroozan Afsharchi, Joshua F. Edwards, Kailash S. Ram, Jingru Huang, Valicia Hale, Ismail El Moudden

Department of Family and Community Medicine Faculty Publications

Background

This cross-sectional study examined whether anxiety and depression symptoms decrease as medical students progress through training (suggesting adjustment disorder) or persist (suggesting chronic conditions), while identifying associated risk factors, including student debt burden and treatment effectiveness.

Methods

We surveyed medical students (years 1-4) at VHS-ODU using a sociodemographic questionnaire and validated screening instruments (GAD-7 for anxiety and PHQ-9 for depression) via RedCap from September to November 2024.

Results

Among 126 students, Scores were higher in Years 2-3 than in Years 1 and 4, but differences by year were not significant (GAD-7 p=0.055; PHQ-9 p=0.352). Students with a prior mental-health …