Medicine and Health Sciences Commons^™

The Role Of Human Sarcosine Dehydrogenase And Endothelial Growth Factor In Early Diagnosis Of Cancer Prostate, Hala Ibrahim Mohamed, Amr Mohamed Mounier Elsofy

Journal of Medicine in Scientific Research

Background: As the second most common cancer in males, prostate cancer contributes significantly to cancer-related deaths. Prostate-specific antigen (PSA) test and digital rectal examinations are used to identify it, albeit PSA screenings frequently produce unreliable results. Initial symptoms may include sexual dysfunction and urinary problems. The standard diagnostic method is biopsies, which are carried out under the direction of ultrasound or magnetic resonance imaging (MRI). However, they are risky and can result in infections and erectile dysfunction, which emphasizes the need for better biomarkers. Sarcosine and vascular endothelial growth factor are important metabolites associated with the progression of prostate cancer, …

Are The Risks Of Asthma And Allergic Diseases In Children Born By Cesareansection (Cs) Influenced By Maternal Factors (E.G., Maternal Asthma, Diet, Antibiotic Use During Pregnancy)?, Rehab Fawzy Abdel Mohsen Soliman, Samar Mahmoud Ahmed, Yasmen Ahmed Said, Shaimaa Mohamed Hassan, Dalia Hassanin Hussin, Dina Gaber Soliman, Zeinab Abdalla Ali

Journal of Medicine in Scientific Research

Background and Aim The increase in the number of Cesarean Section deliveries (CS) in the world has triggered questions about the possible long-term health consequences for the children being delivered, particularly the chances of being affected by asthma and other allergic ailments. Some prior studies suggested that CS deliveries may negatively influence immune system development due to altered microbial colonization and an increased risk of respiratory morbidities. However, trying to separate the impact of delivery methods and the maternal as well as the surroundings is a hard nut to crack. The present study aims to establish whether maternal asthma, diet, …

Effect Of Lateral And Backward Walking Training On Balance In Children With Hemiparesis: A Comparative Randomized Controlled Trial, Seham M. Abd El-Moghny, Mohamed I. Elsepaee

Journal of Medicine in Scientific Research

Background: Hemiparesis, a common consequence of cerebral palsy (CP), significantly impairs motor function, leading to asymmetrical gait, poor balance, and reduced mobility in affected children. The resulting functional limitations can negatively impact a child's participation in daily activities, social interactions, and overall quality of life. Purpose: To investigate and compare the effectiveness of lateral and backward walking training with mirror visual feedback on standing balance in children with hemiparesis. Methods: Ninety children with hemiparesis, ages five to seven, of both sexes who met the following inclusion criteria were included in the study: They have spasticity at grades 1+ to 2 …

Does Subarachnoid Dexmedetomidine Decrease The Incidence Of Shivering And Postoperative Nausea And Vomiting In Cesarean Section?A Prospective Randomized Controlled Trial, Ali El-Sayed Khayal, Amr Abdellatif

Journal of Medicine in Scientific Research

Background: Spinal anesthesia during cesarean sections is associated with a number of common problems, including postoperative nausea and vomiting (PONV), which can make the mother feel uneasy and negatively impact the perioperative results. The neuraxial adjuvant dexmedetomidine has shown promise since it is a very selective α₂- adrenergic receptor agonist that can improve spinal anesthesia and also provide extra sedative and anti-shivering effects. Objective:To evaluate the effect of adding 5μg intrathecal dexmedetomidine to hyperbaric bupivacaine on the incidence of shivering and PONV during elective cesarean section. Patients and Methods: Elective caesarean sections under spinal anesthesia were elective for 100 healthy …

Efficacy And Safety Of General Anaesthesia Versus Local Anaesthesia With Iv Sedation In Transcatheter Aortic Valve Implantation (Tavi), Reham Salah, Ahmed Kamel Abdelghany Hassan, Sherif Ahmed Kamal Elhendawy

Journal of Medicine in Scientific Research

The optimal anesthetic approach for transcatheter aortic valve implantation (TAVI) remains a subject of ongoing debate. Although general anesthesia (GA) allows greater procedural control and airway security, local anesthesia with conscious sedation (LACS) may facilitate faster postoperative recovery and reduce procedure-related complications. This study aimed to compare the efficacy and safety of GA versus CS in patients undergoing transfemoral TAVI.

Comparison Between Central Corneal Thickness Measured By Anterior Segment Optical Coherence Tomography And Pentacam, Osama Ramadan Mahmoud, Rabab El Araby Lawash, Hanan Mohamed Abdel Hamid Ahmed

Journal of Medicine in Scientific Research

Background: Central corneal thickness (CCT) is crucial in ophthalmic practice helping diagnosis and management of various conditions such as glaucoma, keratoconus, corneal dystrophy, contact lens use and proceeding refractive procedures assessment. A lot of non-contact modalities are currently available for CCT evaluation including anterior segment optical coherence tomography (AS-OCT) and the Pentacam systems so we are in need of determining the degree of agreement between these instruments to establish an accurate clinical interpretation. Aim: To test correlation between corneal thickness measurements obtained using Pentacam and AS-OCT. Patients and Methods: Our comparative observational study included 50 eyes. CCT was measured in …

Incidental Extracardiac Findings In Cardaic Mr Imaging, Shaimaa S Mohamed, Elhardalo O Mohamed, Mohamed A Ali, Shimaa S Attia

Journal of Medicine in Scientific Research

Background: Cardiac magnetic resonance imaging (cMRI) is recently a pivotal noninvasive technique for comprehensive cardiac assessment, providing detailed cardiac anatomy and motility insights. Given its expansive field of view, cMRI facilitates the identification of incidental extracardiac findings (IEFs), that may have clinical significance beyond the primary cardiac evaluation.

Objective: This study aims to assess the prevalence of incidental extracardiac findings noted in cMRI and to address the most frequent detected lesions.

Methods: A retrospective study was conducted on patients who have done cMRI in the period between July 2021 and July 2023. The study cohort consisted of 219 individuals referred …

Heart-Type Fatty Acid Binding Protein In Early Diagnosis Of Acute Myocardial Infarction, Reem Safwat Mohamad, Asmaa Younis Elsary, Mohamed M. Elbably

Journal of Medicine in Scientific Research

Background: Timely identification of acute myocardial infarction (AMI) plays a vital role in ensuring prompt treatment and better clinical outcomes. Traditional cardiac indicators involving creatine kinase-myocardial band (CK-MB) and cardiac troponin I (cTnI) demonstrate reduced diagnostic accuracy through the initial hours after symptom presentation.

Aim: This research aimed to assess the diagnostic accuracy of heart-type fatty acid-binding protein (H-FABP) in comparison with cTnI, CK-MB, and lactate dehydrogenase (LDH) among cases presenting with acute chest pain, with particular focus on its role in early AMI detection.

Methods: A case-control investigation was conducted involving 60 AMI patients from the National Heart Institute …

Early Outcome Of Coronary Artery Bypass Grafting In 1,000 Egyptian Patients And Predictors Of Hospital Mortality, Ramdan Ibrahim Mohammed Ouf

Journal of Medicine in Scientific Research

Background Coronary artery bypass grafting (CABG) is a prevalent therapeutic intervention for the management of coronary artery disease. CABG significantly increases life expectancy. However, it is associated with peri-operative morbidity and mortality. Aim of the study to analyze the clinical and demographic attributes of patients undergoing isolated CABG and determine the early outcomes and the predictors of hospital mortality. Methods This is a retrospective observational study was conducted in National Heart Institute to describe the demographic and clinical characteristics of 1,000 Egyptian patients undergoing isolated CABG between January 2021 and January 2024. Results Our study included 1000 patients (mean age …

Comparison Of Suture Materials In Pfannensteil Incision Closure, Ali Elsayed Khayal, Ahmed Alsayed Kassab

Journal of Medicine in Scientific Research

Background: Surgeons worldwide perform C-sections more often than almost any other procedure, a trend that shows a steady and ongoing increase. Despite its safety profile, postoperative wound complications remain a significant source of maternal morbidity, prolonged hospitalization, and increased healthcare costs. Optimal skin closure technique following Pfannenstiel incision remains controversial, particularly regarding the choice between absorbable braided and non-absorbable monofilament sutures.

Objective: To compare wound morbidity and surgical outcomes following Pfannenstiel skin closure using polyglactin 910 (Vicryl) versus polypropylene (Prolene) in women undergoing cesarean delivery.

Methods: This prospective randomized controlled trial included 200 women undergoing elective or emergency cesarean section …

Patient Pathways And Outcomes Following Referral To A Dedicated Clinic For Tavi Program: Insights From The Egyptian National Heart Institute, Ramy Mohamed Omar, Ahmad Hassanen Gaber, Tarek M Abdel Aziz Elkholy

Journal of Medicine in Scientific Research

Background

The most common valvular heart disease in elderly populations and with a dismal prognosis in the case of its development is degenerative aortic stenosis. The use of transcatheter aortic valve implantation (TAVI) has transformed the treatment of the entire surgical risk spectrum, but there is limited real-world data that define the patterns of treatment and post-treatment results in the Middle East and North Africa (MENA) region.

Objectives

To characterize the pattern of treatment allocation, clinical and procedural outcome, and predictors at the baselines of six months mortality in patients in a row who were referred to a specialist assessment …

Comparison Of Dexmedetomidine And Ketamine Versus Propofol And Ketamine For Procedural Sedation In Children Undergoing Minor Cardiac Procedures In Cardiac Catheterization Laboratory, Reham Salah, Amr Ahmed Samir

Journal of Medicine in Scientific Research

Background: The optimal anesthetic approach for the care of pediatric patients facing cardiac catheterization stays undefined. Therefore, this study sought to equivalence the impact of ketamine-propofol and ketamine-dexmedetomidine mixtures on recovery duration and hemodynamic parameters in pediatric patients suffering trivial procedures and cardiac catheterization, while sedated for the treatment of numerous congenital heart diseases.

Materials and Method: One hundred twenty-six pediatric patients, irrespective of sex, scheduled for cardiac catheterization were arbitrarily billed to one of two groups: a propofol-ketamine group (PK) and a dexmedetomidine-ketamine group (DK), every comprising sixty-three patients. Group (DK) established Dexmedetomidine iv infusion 1µg/kg over ten min …

Association Between Red Cell Distribution Width And Type 2 Diabetes Mellitus, Walaa Saad Mohammed Ibrahim

Journal of Medicine in Scientific Research

Background:

Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease characterized by hyperglycemia and associated complications. Red cell distribution width (RDW), an index of the variability in red blood cell size, has emerged as a potential biomarker of inflammation and vascular risk.

Objective:

To assess the association between RDW and T2DM and its relation to glycemic control

Patients and Methods:

The current case-control study enrolled 40 T2DM patients and 20 age- and sex-matched healthy controls. Data collected included fasting blood sugar (FBS), 2-hour postprandial glucose (2hPP), HbA1c, lipid profile, albumin/creatinine ratio (ACR), and RDW. Statistical analysis included …

Role Of Complete Blood Cells Indices In Predicting Neonatal Sepsis Mortality, Sohaila Ali Abd El-Halim, Marwa Taha, Fifi Helmy Aboualy, Raghda Samir Abdellatif, Mai Mohammed Mostafa

Journal of Medicine in Scientific Research

Background: Neonatal sepsis remains a leading cause of morbidity and mortality in newborns. Identifying reliable prognostic markers is crucial for early diagnosis and treatment. Elevated levels of C-reactive protein (CRP) and increased platelet distribution width (PDW) have been associated with adverse outcomes in septic neonates. Objective: This study was performed in an attempt to assess the predictive value of Complete Blood Count (CBC) indices, including red cell distribution width (RDW), mean platelet volume (MPV), and PDW for mortality in septic neonates. Patients and Methods: This cohort study was conducted in the neonatal intensive care unit (NICU) of Mataria Teaching Hospital …

Identification Of The Seventh Cervical Vertebra By Palpation With Neck Rotation And Side Bending In Patients With Neck Pain., Eslam Elsayed Ali Shohda, Malaka Abdelmoniem Ibrahim El Khawaga, Amr Abdelaziz Hanafi Mohamed

Journal of Medicine in Scientific Research

Background: Precise localization of vertebral levels through clinical examination represents an essential competency for healthcare professionals across multiple disciplines. The present study sought to assess the reliability of identifying the seventh cervical vertebra (C7) via palpation during cervical rotation and side bending in individuals experiencing neck pain.

Materials and Methods: A cross-sectional study was carried out in the physiotherapy outpatient department of Al-Ahrar Teaching Hospital, located in Zagazig, Egypt. Thirty individuals with complaints of neck pain were recruited for participation. The seventh cervical vertebra (C7) was determined by palpating the most mobile vertebra among the three most prominent cervical segments …

The Role Of Evaluation Of Fetal Lung By Gray Scale & Doppler Us In Prediction Of Fetal Lung Maturity, Rana Elshennawy Nasr Ammar, Diaa Monir Ajlan, Mohammad Abdellatif Nassar, Shereef Lofty Elshwaikh

Journal of Medicine in Scientific Research

Background Neonatal respiratory distress syndrome (RDS) is a major cause of neonatal morbidity and mortality, especially in preterm infants. Traditional assessments of fetal lung maturity often require amniocentesis, an invasive procedure with significant risks. Noninvasive ultrasound-based methods could help optimize the timing of preterm delivery. Aim To determine whether the gray-scale echogenicity of the fetal lung and Doppler indices of the fetal main pulmonary artery (MPA) can predict fetal lung maturity and the risk of neonatal RDS in late preterm pregnancies. Patients & Methods A prospective cohort study was performed in the Obstetrics and Gynecology Department of Tanta University Hospitals …

Physiological, Cytogenetic, And Nutrition Effects Of Garcinia Cambogia And Ginkgo Biloba Aqueous Extracts On The Reproductive Functions Of Diabetic Male Rats, Marwa E. Hassan, Mahmoud M. Ahmed, Sherien A. Montaser, Sherein S. Abdelgayed, Asmaa M.I. El Gamal

Journal of Medicine in Scientific Research

Introduction

Diabetes disturbed humans from living normally, while Nature tries to help us again. Remarkable herbs biodiversity reflects a wide array of mechanisms.

Aim

Present study aims to track male annoying consequences of diabetic on fertility, trying to improve these hazards using two different herbs Garcinia cambogia and Ginkgo biloba.

Materials and methods

30 male Albino Sprague Dawely rats in six groups (5 rats each). Groups; 1^st group (negative control). 2^nd and 3^rd were treated orally with (200 mg/kg bw) for both G. cambogia and G. biloba. 4^th was +ve control (diabetic rat model) induced …

How Do Students Come Across Occupational Therapy And What Makes Them Want To Study Occupational Therapy? Implications For Recruitment, Mette Eg Bruun, Mette Krohn, Sofie Balle Riis, Lene Tanggaard, Tina Helle

Journal of Occupational Therapy Education

Recruitment challenges in occupational therapy education vary globally. To address workforce needs, it is necessary to examine the factors influencing students’ decisions to pursue occupational therapy. This study investigated how students discovered occupational therapy, what they found appealing about the profession, the influence of study location, and demographic differences between students enrolled in an urban university city and a rural district. Three focus group interviews with 15 occupational therapy students were conducted, supplemented by descriptive statistics comparing student characteristics across urban and rural programs. Qualitative analysis identified five categories: (1) discovering occupational therapy by chance, (2) the power of occupational …

Recalibrating Readiness: Pandemic Impact On Ot Admissions, Bridget J. Hahn, Kajol Patel, Jacquelyn A. Siegel, Jessica Rappaport, Michelle Mcfall-Johnsen, Kia A. Burks

Journal of Occupational Therapy Education

This study explored shifts in occupational therapy applicant characteristics across two distinct time periods: pre- and post-COVID-19, while also describing admissions policy changes implemented by an urban Midwestern Occupational Therapy Doctorate (OTD) program. Retrospective data from admissions records from 917 applicants (2017 – 2024) were grouped into pre-COVID (2017 – 2020) and post-COVID (2021 – 2024). Academic, pre-professional, interview, and underrepresented minority (URM) status was compared using independent t-tests and chi-square analyses. Cumulative grade point average (GPA) and research experience increased post-pandemic, while pre-professional experience and interview performance declined. The proportion of URM applicants rose significantly from 8.1% pre-COVID to …

Sketching Ot Theory: The Meaning Of Visual Notetaking To Learning Occupational Therapy Theory For Ot Students, Julia Henderson, Delainey Ebel, Ilona Jones, Katie Lee Bunting

Journal of Occupational Therapy Education

Visual notetaking is a creative learning strategy used in health professions education. This study defines it as any form of notes, recorded using physical or electronic means, that are not solely text-based, but incorporate some degree of color, symbolism, shapes, diagrams, and/or other visual imagery to represent concepts. While no previous studies have investigated visual notetaking in the context of occupational therapy education, occupational therapy’s prevalent use of visual representations to convey complex, relational, and holistic theoretical concepts suggests that visual notetaking may have potential as an inherently aligned and effective pedagogical approach for teaching occupational therapy theory. Our study …

Comparing Pre-Occupational Therapy Student Intercultural Competence Through Local And Global Service Learning, Leah S. Dunn, Diane Ceo-Difrancesco

Journal of Occupational Therapy Education

This study examined undergraduate pre-occupational therapy student intercultural competence (ICC) development through a local or global service-learning experience. Using a mixed-method approach, responses to the Inventory for Assessing the Process of Cultural Competence among Healthcare Professions-Student Version (IAPCC-SV) were compared as well as a content analysis of student essays before and after the service-learning experience to determine ICC growth. Both groups demonstrated ICC growth, but global participants continued their development past the experience. Student essays revealed themes of dissonance, reflection, transformation, and advocacy, with local students focusing on clients and global students adopting broader advocacy goals. Immersive experiences in occupational …

Study Approaches And Mindset In Predicting Entry-Level Occupational Therapy Student Well-Being: A Multiple Linear Regression Analysis, Elena Wong Espiritu, Katie Eison, Maya Pakulski, Alandry Vise, Alexandria West, Ava Woessner

Journal of Occupational Therapy Education

Academic factors (grades, assignments, study approaches, study strategies, rigorous curriculums, workload) and mindset factors (academic resilience, educational self-efficacy) are known individual factors that impact student well-being. However, if and how these factors in combination predict well-being in occupational therapy students has not been explored. The purpose of this study was to explore study approaches and mindset factors in predicting entry-level occupational therapy student well-being. Entry-level occupational therapy students (master’s and doctorate) from across the United States were recruited (N = 305). Using a quantitative cross-sectional design, data was collected using four standardized assessments and analyzed using a multiple linear regression. …

Perceived Impacts Of Confucianism On Placement Experiences Of Hong Kong Pre-Registration Occupational Therapy Students In The United Kingdom, Hin Yuet Li, Sarah Louise Mcginley, Rachel Dadswell, Rachel Houweling

Journal of Occupational Therapy Education

This study explored the views of Hong Kong pre-registration occupational therapy (OT) students in the United Kingdom (UK) about how Chinese culture influenced their practice placement experiences. Students from diverse cultural backgrounds may encounter various challenges during OT placements, but little is known about how OT students from Hong Kong—where Confucianism traditionally shapes workplace expectations and the hierarchical teacher‑student relationship—experience placements in the UK. Two online focus groups to collect qualitative data were conducted in November 2022 with four participants who were UK-based OT students from Hong Kong (N=8 in total), two facilitators (OT students from Hong Kong, based in …

From Classroom To Care: A Pilot Level I Fieldwork Experience Building Acute Care Self-Efficacy, Hannah Y. Oldenburg, Jennifer Bergstrom, Traci Kruse, Tamra Trenary, Corey Mcgee

Journal of Occupational Therapy Education

Level I fieldwork provides an opportunity for occupational therapy students to be exposed to the occupational therapy framework and process across various practice settings. This study addresses a gap in the literature regarding introductory fieldwork experiences for occupational therapy students in complex medical settings, specifically acute care. Researchers implemented a seven-week Level I fieldwork experience at two Midwest trauma centers, utilizing a mixed-methods, two-cohort design with 12 students and 16 practitioners. The program featured a blended Level I fieldwork supervision model, combining faculty-led and traditional on-site supervision. Over the seven-week period, students showed significant improvement in their perceived self-efficacy regarding …

Examining The Relationship Between Musculoskeletal Knowledge And Fieldwork Performance Among Canadian Student Occupational Therapists, Madelyn Walther, Viansa Guiotto, Rhona Anderson, Emily S. Ho

Journal of Occupational Therapy Education

To evaluate the physical aspects of occupational performance, occupational therapists must understand the anatomical structure and function of the body. As such, occupational therapy academic programs must provide sufficient foundational musculoskeletal (MSK) education to prepare student occupational therapists for successful clinical practice. There is a paucity of research on MSK educational needs, and the relationship between student occupational therapists’ MSK academic outcomes and fieldwork performance. This study examined the relationship between MSK anatomy course academic grades and fieldwork performance indicators on the Competency-Based Fieldwork Evaluation for Occupational Therapists (CBFE-OT) of student occupational therapists. A mixed-methods sequential explanatory design was conducted …

Effectiveness Of The Aota Fieldwork Educator Certificate Program: A Cross-Sectional Survey Of Participants, Susan M. Higgins, Tiffany Benaroya

Journal of Occupational Therapy Education

Fieldwork educators are essential in educating future occupational therapy practitioners, yet they are often not formally trained for this role. Fieldwork educator preparation programs may help strengthen educator effectiveness; however, limited research has examined the impact of these programs. The American Occupational Therapy Association (AOTA) Fieldwork Educator Certificate Program (FWECP) is a two-day professional development course designed to enhance the supervisory and teaching competencies of fieldwork educators. This study examined the effectiveness of the FWECP from the perspective of participants who completed the program between June 2019 and June 2024. An anonymous retrospective survey was distributed to past participants, yielding …

Generative Artificial Intelligence Application In Occupational Therapy Education, James Wersal, Justin Mason, Mary Shotwell

Journal of Occupational Therapy Education

Generative artificial intelligence (GenAI) is a developing technology within Higher Education Institutions with substantial potential to transform teaching pedagogy, improve individualized learning experiences, and automate administrative functions. GenAI has the potential to bring significant enhancements by advancing adaptive learning interfaces, customized learning materials, and automate administrative support. Despite these benefits, ethical considerations, data privacy, and the risk of over-reliance should be considered prior to using GenAI. The authors highlight how GenAI is supported by adult learning theory and provide practical strategies for incorporating GenAI in the occupational therapy curricula and to support the faculty role. The impact of GenAI on …

The Psychosocial Occupational Therapy Competency Assessment, Revised- Pot-Ca(R), Jenna C. Yeager, Derek Piggott

Journal of Occupational Therapy Education

The Psychosocial Occupational Therapy Competency Assessment (POT-CA) was originally published in 2017 as a framework for assessing student development of foundational skills in evaluation, clinical reasoning, and therapeutic interactions in an occupational therapy psychosocial theory and practice course. The COVID-19 global pandemic necessitated the adaptation of this final student competency assessment for virtual administration. The Canadian Occupational Performance Measure (COPM) was selected as the performance-based element of the competency assessment in lieu of the previously required Allen Cognitive Level Screen (ACLS-5), which was unavailable to students due to pandemic restrictions. The purpose of this article is to present an analysis …

Development Of A Comprehensive Practical Exam (Cope) Assessment Process For Occupational Therapy Doctoral Students, Robert E. Larson, Cynthia Tiongco, Sandra M. Whisner, Laurie D. Stelter, Laura Alexander, Megan R. Taylor, Molly Setliff, Paula Perkins, Belinda D. Alexander, James Matthew D. Geddie

Journal of Occupational Therapy Education

Measures are needed to ensure students are adequately prepared for clinical experiences. A Comprehensive Practical Exam (CoPE) was developed based on high fidelity simulation and an Observed Structured Clinical Examination format to assess readiness for Level II fieldwork. Teams of faculty developed multiple case simulations with consistent components across the cases for first- and second-year student cohorts. Rubrics were developed for grading student performance on the simulations with categories required for Level I fieldwork completion as well as other components required for success on Level II fieldwork. The CoPE included three components: chart review/preparation, client interaction, and documentation. The first-year …

Hands-On: Integrating Active Learning Into An Upper Extremity Occupational Therapy Elective, Jennifer Radziak, Katie Jones, Kelsey Picha

Journal of Occupational Therapy Education

In an effort to provide students with advanced clinical practice skills, several occupational therapy elective courses were developed. The current article describes an educational innovation that involved an in-person elective course for graduate second year Master of Science in Occupational Therapy students that focused on the upper extremity. The course was team-taught, promoted active learning, and used unique activities to engage students in the learning process. Relevant evidence-based practice literature and clinical guidelines were incorporated into the course to teach students about the treatment of upper extremity conditions. The active learning strategies implemented in the course included fresh donor dissection, …