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Articles 9481 - 9510 of 194108

Full-Text Articles in Engineering

The Hole Sealing Technology Of Solid-Liquid Materials With Three Pluggings And Two Injections For Gas Extraction Hole In The Coal Mine, Shiyao Yu, Xianbo Su, Jinxing Song, Qian Wang, Zhenjiang You Nov 2022

The Hole Sealing Technology Of Solid-Liquid Materials With Three Pluggings And Two Injections For Gas Extraction Hole In The Coal Mine, Shiyao Yu, Xianbo Su, Jinxing Song, Qian Wang, Zhenjiang You

Research outputs 2022 to 2026

The sealing quality of the gas extraction holes determines the extracted gas concentration. Based on this, the paper reveals the basic principle of hole sealing by analyzing the gas leakage mechanism of the borehole. The hole sealing technology of solid-liquid materials with three pluggings and two injections for the gas extraction hole is proposed, and the hole sealing device and material are developed. Through testing the granularity distribution of the solid material, as well as the surface tension and contact angle of the slurry, the hole sealing material that can meet the requirements of accessible, sticky, and anti-deformation is selected. …


Predictions Of Household Water Affordability Under Conditions Of Climate Change, Demographic Growth, And Fresh Groundwater Depletion In A Southwest Us City Indicate Increasing Burdens On The Poor, Josiah M. Heyman, Alex S. Mayer, Jessica Alger Nov 2022

Predictions Of Household Water Affordability Under Conditions Of Climate Change, Demographic Growth, And Fresh Groundwater Depletion In A Southwest Us City Indicate Increasing Burdens On The Poor, Josiah M. Heyman, Alex S. Mayer, Jessica Alger

Michigan Tech Publications

Reduced river flows and groundwater depletion as a result of climate change and population growth have increased the effort and difficulty accessing and processing water. In turn, residential water costs from municipal utilities are predicted to rise to unaffordable rates for poor residential water customers. Building on a regional conjunctive use model with future climate scenarios and 50-year future water supply plans, our study communicates the effects of climate change on poor people in El Paso, Texas, as water becomes more difficult and expensive to obtain in future years. Four scenarios for future water supply and future water costs were …


Predicting The Stability Of Open Stopes Using Machine Learning, Alicja Szmigiel, Derek B. Apel Nov 2022

Predicting The Stability Of Open Stopes Using Machine Learning, Alicja Szmigiel, Derek B. Apel

Journal of Sustainable Mining

The Mathews stability graph method was presented for the first time in 1980. This method was developed to assess the stability of open stopes in different underground conditions, and it has an impact on evaluating the safety of underground excavations. With the development of technology and growing experience in applying computer sciences in various research disciplines, mining engineering could significantly benefit by using Machine Learning. Applying those ML algorithms to predict the stability of open stopes in underground excavations is a new approach that could replace the original graph method and should be investigated. In this research, a Potvin database …


Designing And Cnc Machine Valve Sub-Plates And Quick Mounts For Hydraulic Power Training Systems, Connor Maxam Nov 2022

Designing And Cnc Machine Valve Sub-Plates And Quick Mounts For Hydraulic Power Training Systems, Connor Maxam

Morehead State Theses and Dissertations

A thesis presented to the faculty of the College of Business and Technology at Morehead State University in partial fulfillment of the requirements for the Degree of Master of Science by Connor Maxam on November 22, 2022.


Cocm: Co-Occurrence-Based Consistency Matching In Domain-Adaptive Segmentation, Siyu Zhu, Yingjie Tian, Fenfen Zhou, Kunlong Bai, Xiaoyu Song Nov 2022

Cocm: Co-Occurrence-Based Consistency Matching In Domain-Adaptive Segmentation, Siyu Zhu, Yingjie Tian, Fenfen Zhou, Kunlong Bai, Xiaoyu Song

Electrical and Computer Engineering Faculty Publications and Presentations

This paper focuses on domain adaptation in a semantic segmentation task. Traditional methods regard the source domain and the target domain as a whole, and the image matching is determined by random seeds, leading to a low degree of consistency matching between domains and interfering with the reduction in the domain gap. Therefore, we designed a two-step, three-level cascaded domain consistency matching strategy—co-occurrence-based consistency matching (COCM)—in which the two steps are: Step 1, in which we design a matching strategy from the perspective of category existence and filter the sub-image set with the highest degree of matching from the image …


Quantifying A 21-Year Surface Water And Groundwater Interaction In A Ridge And Valley Lake Environment Using A Highly Constrained Modeling Approach, Richard T. Bowers Jr. Nov 2022

Quantifying A 21-Year Surface Water And Groundwater Interaction In A Ridge And Valley Lake Environment Using A Highly Constrained Modeling Approach, Richard T. Bowers Jr.

USF Tampa Graduate Theses and Dissertations

Karst lakes are ubiquitous in ridge terrain settings in limestone aquifer coastal plain environments. In west-central Florida, these lakes are frequently connected to the Upper Floridan aquifer and have unique aquifer recharge characteristics. They have been selectively studied because they commonly have no or very limited surface water discharge and limited drainage areas, have appreciable surface water and groundwater interaction and leak to the deep aquifer. An innovative modeling approach was developed to collectively understand and more precisely quantify this vertical leakage, both from a lake-specific and regional water budget standpoint, for a 21-year study period (2000-2020). A unique, calibrated …


Influence Of Particle Size Distribution And Initial Dry Density On The Characteristics Of Subgrade Mud Pumping, Yu Ding, Yu Jia, Xuan Wang, Jia-Sheng Zhang, Xiao-Bin Chen, Hao Luo, Yu Zhang Nov 2022

Influence Of Particle Size Distribution And Initial Dry Density On The Characteristics Of Subgrade Mud Pumping, Yu Ding, Yu Jia, Xuan Wang, Jia-Sheng Zhang, Xiao-Bin Chen, Hao Luo, Yu Zhang

Rock and Soil Mechanics

The subgrade mud pumping of heavy-haul railway is widespread and harmful, which seriously affects the stability of tracks and the safety of train operation. The properties of railway subgrade soil, such as the particle gradation, the void ratio, have a significant impact on the characteristics of subgrade mud pumping under train load. In this study, a series of remolded samples consisting of silty clay and different content of Kaolin was subjected to mud pumping tests with a self-developed test model. The influence of varying particle gradations (Kaolin content) and initial dry densities (void ratio) on axial strain, excess pore water …


Wind Tunnel Research, Dynamics, And Scaling For Wind Energy, Majid Bastankhah, Raul Bayoan Cal, Nicholas Hamilton Nov 2022

Wind Tunnel Research, Dynamics, And Scaling For Wind Energy, Majid Bastankhah, Raul Bayoan Cal, Nicholas Hamilton

Mechanical and Materials Engineering Faculty Publications and Presentations

The interaction of wind turbines with turbulent atmospheric boundary layer (ABL) flows represents a complex multi-scale problem that spans several orders of magnitudes of spatial and temporal scales. These scales range from the interactions of large wind farms with the ABL (on the order of tens of kilometers) to the small length scale of the wind turbine blade boundary layer (order of a millimeter). Detailed studies of multi-scale wind energy aerodynamics are timely and vital to maximize the efficiency of current and future wind energy projects, be they onshore, bottom-fixed offshore, or floating offshore. Among different research modalities, wind tunnel …


A Numerical Method For Studying The Effectiveness Of Polyurethane Foam As Personal Protective Equipment Material, Lamia Tahsin Aroni Nov 2022

A Numerical Method For Studying The Effectiveness Of Polyurethane Foam As Personal Protective Equipment Material, Lamia Tahsin Aroni

Electronic Thesis and Dissertation Repository

This thesis documents the characterization of flexible polyurethane foam (FPF) to be used as a personal protective equipment material. Polyurethane samples were tested experimentally to calculate the physical properties which were later re-created using a numerical model. A discrete element modeling software was used to generate the geometry to mimic the physical properties of FPF. The pore level numerical model was used to calculate the possible rate of particle penetration for a range (0.2 -200) µm of particle sizes. A parametric study was done using the polyurethane foam parameters to understand the breathing dynamics under steady conditions. The possible particle …


Print3d, A Service-Learning Project For Improving Visually Impaired Accessibility Through Educational 3d Printing, Oscar R. Lozano Nov 2022

Print3d, A Service-Learning Project For Improving Visually Impaired Accessibility Through Educational 3d Printing, Oscar R. Lozano

Journal of Pre-College Engineering Education Research (J-PEER)

Well-executed service-learning projects are a high-value educational element. However, these projects commonly focus on overused topics and unbalanced executions which can produce the opposite effect to that desired when working with groups of people with functional diversity. PRINT3D is a service-learning project aimed at improving accessibility for people with visual disabilities while helping primary and secondary school students learn basic engineering skills through 3D design and printing. Under the support of the European Erasmus+ Programme, this project brought together nongovernmental organizations, teacher professional development centers, business enterprises, and educational centers to collaborate for two school years. The project activities aimed …


Stochastic Models For Resilience Assessment And Improvement, Weimar Ardila Rueda Nov 2022

Stochastic Models For Resilience Assessment And Improvement, Weimar Ardila Rueda

USF Tampa Graduate Theses and Dissertations

Resilience refers to the ability of a system to absorb and mitigate the impact of potential disruptions and return to normal operational conditions. The above notion of resilience allows us to distinguish two stages in a system's post-disruption response, the absorptive dimension and the recovery dimension. The absorptive dimension is related to a system's robustness and capacity to mitigate initial loss posterior to a disruption. Meanwhile, the recovery dimension is the system's rapidity to return and reach an acceptable level of functionality after the disruption occurrence.

A social-physical (SP) system's post-disruption response is related to its resilience capacity so building …


An Exploration Of Recent Intelligent Image Analysis Techniques For Visual Pavement Surface Condition Assessment., Waqar Shahid Qureshi, Ibrahim Hassan Syed, Susan Mckeever, David Power, Brian Mulry, Kieran Feighan, Dympna O'Sullivan Nov 2022

An Exploration Of Recent Intelligent Image Analysis Techniques For Visual Pavement Surface Condition Assessment., Waqar Shahid Qureshi, Ibrahim Hassan Syed, Susan Mckeever, David Power, Brian Mulry, Kieran Feighan, Dympna O'Sullivan

Articles

Road pavement condition assessment is essential for maintenance, asset management, and budgeting for pavement infrastructure. Countries allocate a substantial annual budget to maintain and improve local, regional, and national highways. Pavement condition is assessed by measuring several pavement characteristics such as roughness, surface skid resistance, pavement strength, deflection, and visual surface distresses. Visual inspection identifies and quantifies surface distresses, and the condition is assessed using standard rating scales. This paper critically analyzes the research trends in the academic literature, professional practices and current commercial solutions for surface condition ratings by civil authorities. We observe that various surface condition rating systems …


Spacecraft Systems & Navigation, Christopher Vanacore Nov 2022

Spacecraft Systems & Navigation, Christopher Vanacore

Student Works

This textbook is steered towards higher educational course entailed in Commercial Space Operations. This textbook will be covering in detail Orbital Satellites, and Spacecraft. These topics are discussed according to their application, design, and environment. The power system, shielding and communication systems are reviewed along with their missions, space, environment and limitations. Any vehicle, whether manned or unmanned, intended for space travel is a spacecraft. A spacecraft's required systems and equipment depend on the information it will acquire and the tasks it will perform. Although their levels of sophistication vary widely, they re all subject to the harsh conditions of …


Metascriptura: A General Data Provenance Framework, Maria Joseph Israel Nov 2022

Metascriptura: A General Data Provenance Framework, Maria Joseph Israel

Engineering Ph.D. Theses

Digital technology makes it easy to generate and distribute large volumes of data. However, it has also complicated the process of verifying and validating sources of data and their derivatives risking obfuscation of truth amidst the deluge of data. To address this issue, I trace and develop an approach based on data provenance tracking. Specifically, I make it possible to deep trace the origins and lineages of data, by applying state-of-the-art data provenance technologies, which I extend beyond traditional data provenance applications. In this dissertation, I demonstrate that with the right data infrastructure it is feasible to grant greater agency …


Passive Cooling Analysis Of An Electronic Chipset Using Nanoparticles And Metal-Foam Composite Pcm: An Experimental Study, Faisal Hassan, Abid Hussain, Furqan Jamil, Adeel Arshad, Hafiz Muhammad Ali Nov 2022

Passive Cooling Analysis Of An Electronic Chipset Using Nanoparticles And Metal-Foam Composite Pcm: An Experimental Study, Faisal Hassan, Abid Hussain, Furqan Jamil, Adeel Arshad, Hafiz Muhammad Ali

Research outputs 2022 to 2026

Thermal management of electronic components is critical for long-term reliability and continuous operation, as the over-heating of electronic equipment leads to decrement in performance. The novelty of the current experimental study is to investigate the passive cooling of electronic equipment, by using nano-enriched phase change material (NEPCM) with copper foam having porosity of 97 %. The phase change material of PT-58 was used with graphene nanoplatelets (GNPs) and magnesium oxide (MgO) nanoparticles (NPs), having concentrations of 0.01 wt. % and 0.02 wt. %. Three power levels of 8 W, 16 W, and 24 W, with corresponding heating inputs of 0.77 …


Space Science In Manned Space Flight, Deep Space Exploration And Scientific Satellite Programs, Ji Wu Nov 2022

Space Science In Manned Space Flight, Deep Space Exploration And Scientific Satellite Programs, Ji Wu

Bulletin of Chinese Academy of Sciences (Chinese Version)

In order to implement President Xi's instruction on promoting space science, space technology, and space application all together, national space programs have been developed fast, which are witnessed recently. Space science has become the hot research topic for more and more universities and research institutions. Nevertheless, there are still questions and puzzles about how could space science play its role in manned spaceflight, deep space exploration, and scientific satellites. This paper discusses the role of space science in all three kinds of space programs, starting from the history of space science, and the characteristics of manned space flight, deep space …


Development Status And Enlightenment Of Space-Time Reference For Space Activities, Weigang Xiao, Zhaoxiang Qi Nov 2022

Development Status And Enlightenment Of Space-Time Reference For Space Activities, Weigang Xiao, Zhaoxiang Qi

Bulletin of Chinese Academy of Sciences (Chinese Version)

In this paper, the connotation of space-time reference and its relationship with space activities are described comprehensively. Time system, celestial reference frame, planetary ephemeris and pulsar timing are outlined. The gap between China and abroad development on space-time reference and its causes are analyzed. At the end, some suggestions for future development in China are proposed.


Weatherford Stafford Airport Celebrates New Terminal, Weatherford Daily News Nov 2022

Weatherford Stafford Airport Celebrates New Terminal, Weatherford Daily News

Articles

The City of Weatherford and Oklahoma Aeronautics Commission will host a special public celebration and ribbon cutting of the new Weatherford Stafford Airport Terminal.


Unless stated otherwise within this repository collection, all materials are shared under the following Creative Commons license: [Creative Commons Attribution-NonCommercial 4.0 International License].


Astronaut Snoopy’S 50-Plus Year History With Nasa, Weatherford Daily News Nov 2022

Astronaut Snoopy’S 50-Plus Year History With Nasa, Weatherford Daily News

Articles

"Unknown to many, Snoopy has been working with NASA since the late 1950s"


Unless stated otherwise within this repository collection, all materials are shared under the following Creative Commons license: [Creative Commons Attribution-NonCommercial 4.0 International License].


New Schools Personal For Project Manager, Weatherford Daily News Nov 2022

New Schools Personal For Project Manager, Weatherford Daily News

Articles

Gen. Thomas P. Stafford Elementary started construction in 2020, having a hand in building Stafford Elementary and East Intermediate was personal for Project Manager Shawn Bonner.


Unless stated otherwise within this repository collection, all materials are shared under the following Creative Commons license: [Creative Commons Attribution-NonCommercial 4.0 International License].


Stafford Highlights - Famed Astronaut Returns For 40th Anniversary Of Apollo Mission, Weatherford Daily News Nov 2022

Stafford Highlights - Famed Astronaut Returns For 40th Anniversary Of Apollo Mission, Weatherford Daily News

Articles

Above, Lt. Gen. Thomas P. Stafford speaks during the anniversary event in Weatherford December 7, 2012, of Apollo 17.

At top right, Michael, Thomas and Stas Stafford are pictured with Cosmonaut Valery Kubasov during the 40th Anniversary of Apollo 17 December 7, 2012.


Unless stated otherwise within this repository collection, all materials are shared under the following Creative Commons license: [Creative Commons Attribution-NonCommercial 4.0 International License].


Biomass Characterization And Insulation Optimization Studies, Hussein Awad Kurdi Saad Nov 2022

Biomass Characterization And Insulation Optimization Studies, Hussein Awad Kurdi Saad

Doctoral Dissertations and Master's Theses

This study indicates how biomass materials can be effectively used as naturally sustainable alternatives to insulation materials. Barley grains and oak leaves, straw, and jute are collected, and crushed into powders/ chopped pieces. The physical characteristics are measured to characterize each powder. The biomass powder reinforced composites are manufactured in varying weight ratios. The density and thermal conductivity of composite materials are measured. The properties of composites compared to those of commercial insulation materials are found to be close to them. Furthermore, genetic algorithms (GA) can be used to achieve multi-objective optimization entailing maximizing insulation (minimizing heat transfer) and simultaneously …


Recent Progress In Two Dimensional Mxenes For Photocatalysis: A Critical Review, Tahir Haneef, Kashif Rasool, Jibran Iqbal, Rab Nawaz, Muhammad Raza Ul Mustafa, Khaled A Mahmoud, Tapati Sarkar, Asif Shahzad Nov 2022

Recent Progress In Two Dimensional Mxenes For Photocatalysis: A Critical Review, Tahir Haneef, Kashif Rasool, Jibran Iqbal, Rab Nawaz, Muhammad Raza Ul Mustafa, Khaled A Mahmoud, Tapati Sarkar, Asif Shahzad

All Works

Transition metal carbides and nitrides, generally known as MXenes have emerged as an alternative to improve photocatalytic performance in renewable energy and environmental remediation applications because of their high surface area, tunable chemistry, and easily adjustable elemental compositions. MXenes have many interlayer groups, surface group operations, and a flexible layer spacing that makes them ideal catalysts. Over 30 different members of the MXenes family have been explored and successfully utilized as catalysts. Particularly, MXenes have achieved success as a photocatalyst for carbon dioxide reduction, nitrogen fixation, hydrogen evolution, and photochemical degradation. The structure of MXenes and the presence of hydrophilic …


Wind Plant Controls, Nicholas Hamilton, Dennice Gayme, Raúl Bayoán Cal Nov 2022

Wind Plant Controls, Nicholas Hamilton, Dennice Gayme, Raúl Bayoán Cal

Mechanical and Materials Engineering Faculty Publications and Presentations

The development of operational strategies for wind farms as an integrated plant system to achieve a variety of goals from elevating power production to reducing maintenance needs has generated a great deal of interest in recent years. Achieving these operational goals requires an estimate of the energy available and the wind conditions affecting each turbine. The importance of the aerodynamic interaction of wind turbines with the dynamic atmospheric resource means that wakes (the momentum deficit due to power extraction) and their interactions through the farm have the largest influence on the available energy. Predicting the influence of wakes and their …


Production Of Cellulose-Based Superabsorbent Polymers For Soil Water Retention, Rosa Maria Arredondo Ramirez Nov 2022

Production Of Cellulose-Based Superabsorbent Polymers For Soil Water Retention, Rosa Maria Arredondo Ramirez

Electronic Thesis and Dissertation Repository

Superabsorbent polymers (SAPs) have attracted tremendous attention, with researchers noting that their high water absorption capacity (AC) is valuable for various applications, especially in agricultural contexts. Two types of materials can be used to produce SAPs: fossil-based (which are harmful to the environment) and bio-based (which are significantly more environmentally friendly, given their biodegradability and minimal toxic side effects). Although bio-based SAPs (Bio-SAPs) are preferable due to their environmental merits, their preparation tends to be time consuming and labour intensive, and their AC is still far below expectations. To address these problems, a novel, eco-friendly, cellulose-based superabsorbent polymer (Cellulo-SAP) was …


A Framework For Stable Robot-Environment Interaction Based On The Generalized Scattering Transformation, Kanstantsin Pachkouski Nov 2022

A Framework For Stable Robot-Environment Interaction Based On The Generalized Scattering Transformation, Kanstantsin Pachkouski

Electronic Thesis and Dissertation Repository

This thesis deals with development and experimental evaluation of control algorithms for stabilization of robot-environment interaction based on the conic systems formalism and scattering transformation techniques. A framework for stable robot-environment interaction is presented and evaluated on a real physical system. The proposed algorithm fundamentally generalizes the conventional passivity-based approaches to the coupled stability problem. In particular, it allows for stabilization of not necessarily passive robot-environment interaction. The framework is based on the recently developed non-planar conic systems formalism and generalized scattering-based stabilization methods. A comprehensive theoretical background on the scattering transformation techniques, planar and non-planar conic systems is presented. …


Journal Of Roleplaying Studies And Steam (Jrpssteam) Vol. 1 [2022], Issue 1., Cristo Leon, James Lipuma, Ricardo Morales-Carbajal, Miguel A. Bastarrachea-Magnani, Alain Arriaga, Christian Miguel Rudich De La Rosa, Edgar Meritano, Mauricio Rangel Nov 2022

Journal Of Roleplaying Studies And Steam (Jrpssteam) Vol. 1 [2022], Issue 1., Cristo Leon, James Lipuma, Ricardo Morales-Carbajal, Miguel A. Bastarrachea-Magnani, Alain Arriaga, Christian Miguel Rudich De La Rosa, Edgar Meritano, Mauricio Rangel

Journal of Roleplaying Studies and STEAM

Volumen completo del Journal of Roleplaying Studies and STEAM (JRPSSTEAM) Vol. 1 [2022], Issue 1.


Instructional Message Design: Theory, Research, And Practice (Volume 2), Miguel Ramlatchan, Elisa L. Shaffer, Marissa A. Jimenez, Spyridoula Tsouganatou, Yolanda Montague, Maria Satre, Brittney Heath, Bradley Sanders, Jim Shifflett, Meghan Soldani, Shuree Altantsetseg, Melissa Hatfield, Casey Kohler Nov 2022

Instructional Message Design: Theory, Research, And Practice (Volume 2), Miguel Ramlatchan, Elisa L. Shaffer, Marissa A. Jimenez, Spyridoula Tsouganatou, Yolanda Montague, Maria Satre, Brittney Heath, Bradley Sanders, Jim Shifflett, Meghan Soldani, Shuree Altantsetseg, Melissa Hatfield, Casey Kohler

Distance Learning Faculty & Staff Books

Message design is all around us, from the presentations we see in meetings and classes, to the instructions that come with our latest tech gadgets, to multi-million-dollar training simulations. In short, instructional message design is the real-world application of instructional and learning theories to design the tools and technologies used to communicate and effectively convey information. This field of study pulls from many applied sciences including cognitive psychology, industrial design, graphic design, instructional design, information technology, and human performance technology to name just a few. In this book we visit several foundational theories that guide our research, look at different …


Aeroacoustic Analyses For Noise Reduction Application, Mahmoud M. Abdalmola Nov 2022

Aeroacoustic Analyses For Noise Reduction Application, Mahmoud M. Abdalmola

Mechanical Engineering Theses

In this study, we examine the hypothesis that airflow noise can be reduced by adding metamaterials. The introduction of any obstacle will generate more disturbance in the airflow and therefore add noise. Hence an efficient metamaterial design is required, capable of reducing noise even at higher flow disturbance. In order to examine this hypothesis, we developed a platform to perform isogeometric aeroacoustic analyses to solve Navier stokes equations first. We obtained the velocity fields from fluid-structure analyses and utilized the light-hill analogy to calculate the noise generated as a result of airflow. Then the Helmholtz equation was solved to perform …


Histone Deacetylase 4 And 5 Translocation Elicited By Microsecond Pulsed Electric Field Exposure Is Mediated By Kinase Activity, Zahra Safaei, Gary L. Thompson Iii Nov 2022

Histone Deacetylase 4 And 5 Translocation Elicited By Microsecond Pulsed Electric Field Exposure Is Mediated By Kinase Activity, Zahra Safaei, Gary L. Thompson Iii

Henry M. Rowan College of Engineering Faculty Scholarship

Electroporation-based technologies using microsecond pulsed electric field (µsPEF) exposures are established as laboratory and clinical tools that permeabilize cell membranes. We demonstrate a µsPEF bioeffect on nucleocytoplasmic import and export of enzymes that regulate genetic expression, histone deacetylases (HDAC) -4 and -5. Their μsPEF-induced nucleocytoplasmic transport depends on presence and absence of extracellular calcium ions (Ca2+) for both MCF7 and CHO-K1 cells. Exposure to 1, 10, 30 and 50 consecutive square wave pulses at 1 Hz and of 100 µs duration with 1.45 kV/cm magnitude leads to translocation of endogenous HDAC4 and HDAC5. We posit that by eliciting a rise …