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Full-Text Articles in Engineering

Stream Sediment Monitoring In Morehead Kentucky, Kristopher Krolikowski, Jen O'Keefe Jul 2021

Stream Sediment Monitoring In Morehead Kentucky, Kristopher Krolikowski, Jen O'Keefe

2021 Celebration of Student Scholarship - Oral Presentations

Sediment loads in stream systems play a big role in how overall runoff behaves. Streams naturally transport sediment at various ratios depending on precipitation. When vegetation is removed in upstream environments, sediment loads on streams increase. Sudden increases of sediments in streams can cause many issues, such as flooding or stream re-direction. In Morehead, KY, large-scale logging operations on the ridge above Knapp Avenue and on the ridge above the north end of Allen Avenue have caused increased sediment load in a small stream called Oxley Branch. This stream flows south parallel to Knapp Avenue and along the eastern property ...


Characterization Of Time-Variant And Time-Invariant Assessment Of Suicidality On Reddit Using C-Ssrs, Manas Gaur, Vamsi Aribandi, Amanuel Alambo, Ugur Kursuncu, Krishnaprasad Thirunarayan, Jonathan Beich, Jyotishman Pathak, Amit Sheth May 2021

Characterization Of Time-Variant And Time-Invariant Assessment Of Suicidality On Reddit Using C-Ssrs, Manas Gaur, Vamsi Aribandi, Amanuel Alambo, Ugur Kursuncu, Krishnaprasad Thirunarayan, Jonathan Beich, Jyotishman Pathak, Amit Sheth

Publications

Suicide is the 10th leading cause of death in the U.S (1999-2019). However, predicting when someone will attempt suicide has been nearly impossible. In the modern world, many individuals suffering from mental illness seek emotional support and advice on well-known and easily-accessible social media platforms such as Reddit. While prior artificial intelligence research has demonstrated the ability to extract valuable information from social media on suicidal thoughts and behaviors, these efforts have not considered both severity and temporality of risk. The insights made possible by access to such data have enormous clinical potential - most dramatically envisioned as a trigger ...


Understanding The Effect Of Adaptive Mutations On The Three-Dimensional Structure Of Rna, Justin Cook May 2021

Understanding The Effect Of Adaptive Mutations On The Three-Dimensional Structure Of Rna, Justin Cook

Undergraduate Research and Scholarship Symposium

Single-nucleotide polymorphisms (SNPs) are variations in the genome where one base pair can differ between individuals.1 SNPs occur throughout the genome and can correlate to a disease-state if they occur in a functional region of DNA.1According to the central dogma of molecular biology, any variation in the DNA sequence will have a direct effect on the RNA sequence and will potentially alter the identity or conformation of a protein product. A single RNA molecule, due to intramolecular base pairing, can acquire a plethora of 3-D conformations that are described by its structural ensemble. One SNP, rs12477830, which ...


Designing And Testing Of A System For Aerosolization And Recovery Of Viable Porcine Reproductive And Respiratory Syndrome Virus (Prrsv): Theoretical And Engineering Considerations, Peiyang Li, Jacek A. Koziel, Jeffrey J. Zimmerman, Steven J. Hoff, Jianqiang Zhang, Ting-Yu Cheng, Wannarat Yim-Im, Myeongseong Lee, Baitong Chen, William S. Jenks May 2021

Designing And Testing Of A System For Aerosolization And Recovery Of Viable Porcine Reproductive And Respiratory Syndrome Virus (Prrsv): Theoretical And Engineering Considerations, Peiyang Li, Jacek A. Koziel, Jeffrey J. Zimmerman, Steven J. Hoff, Jianqiang Zhang, Ting-Yu Cheng, Wannarat Yim-Im, Myeongseong Lee, Baitong Chen, William S. Jenks

Agricultural and Biosystems Engineering Publications

Porcine reproductive and respiratory syndrome virus (PRRSV) infections cause significant economic losses to swine producers every year. Aerosols containing infectious PRRSV are an important route of transmission, and proper treatment of air could mitigate the airborne spread of the virus within and between barns. Previous bioaerosol studies focused on the microbiology of PRRSV aerosols; thus, the current study addressed the engineering aspects of virus aerosolization and collection. Specific objectives were to (1) build and test a virus aerosolization system, (2) achieve a uniform and repeatable aerosol generation and collection throughout all replicates, (3) identify and minimize sources of variation, and ...


Pharyngeal Constriction As A Cause For Late Acquisition And Speech Sound Disorders Of Rhotic Sounds In English, Spanish, And French, Connor Mahon May 2021

Pharyngeal Constriction As A Cause For Late Acquisition And Speech Sound Disorders Of Rhotic Sounds In English, Spanish, And French, Connor Mahon

The Downtown Review

This paper attempts to explain why rhotic sounds are cross-linguistically late developing among the sound inventory of children. Included is a summary of the current literature regarding classification of rhotic sounds, an examination of the articulatory movement of the tongue root, and an overview of the clinical implications on the field of speech-language pathology. The evidence presented supports the hypothesis that pharyngeal constriction is characteristic of rhotic sounds in many languages, and that it is related to the relative late acquisition and higher rate of speech sound disorders, as seen in English, Spanish, and French.


Water Exchange Rate Across The Blood-Brain Barrier Is Associated With Csf Amyloid-Β 42 In Healthy Older Adults, Brian T. Gold, Xingfeng Shao, Tiffany L. Sudduth, Gregory A. Jicha, Donna M. Wilcock, Elayna R. Seago, Danny J. J. Wang May 2021

Water Exchange Rate Across The Blood-Brain Barrier Is Associated With Csf Amyloid-Β 42 In Healthy Older Adults, Brian T. Gold, Xingfeng Shao, Tiffany L. Sudduth, Gregory A. Jicha, Donna M. Wilcock, Elayna R. Seago, Danny J. J. Wang

Sanders-Brown Center on Aging Faculty Publications

INTRODUCTION: We tested if water exchange across the blood-brain barrier (BBB), estimated with a noninvasive magnetic resonance imaging (MRI) technique, is associated with cerebrospinal fluid (CSF) biomarkers of Alzheimer's disease (AD) and neuropsychological function.

METHODS: Forty cognitively normal older adults (67–86 years old) were scanned with diffusion‐prepared, arterial spin labeling (DP‐ASL), which estimates water exchange rate across the BBB (kw). Participants also underwent CSF draw and neuropsychological testing. Multiple linear regression models were run with kw as a predictor of CSF concentrations and neuropsychological scores.

RESULTS: In multiple brain regions, BBB kw was positively associated ...


Rethink Everything 2: Markets, Globalization, Development, Nikhilesh Dholakia, Deniz Atik May 2021

Rethink Everything 2: Markets, Globalization, Development, Nikhilesh Dholakia, Deniz Atik

Markets, Globalization & Development Review

No abstract provided.


Regression Analysis Of Pacing When Running A Marathon, Hawkin Starke May 2021

Regression Analysis Of Pacing When Running A Marathon, Hawkin Starke

Industrial Engineering Undergraduate Honors Theses

Regression analysis can be an effective way of examining performance in the marathon event. By splitting up the race into segments or in runner terminology “splits” the significance of each segment as it relates to the total finish time can be explored. Because the idea of splits is already ingrained into the minds of runners, it makes intuitive sense to use these as the metrics to define a race. Additionally, marathons generally make participant age and gender date publicly available which can then be used to find trends within specific demographics. This tailors trends to smaller groups of people, making ...


Design And Control Of A Peristaltic Pump To Simulate Left Atrial Pressure In A Conductive Silicone Model, Jeremy Collins May 2021

Design And Control Of A Peristaltic Pump To Simulate Left Atrial Pressure In A Conductive Silicone Model, Jeremy Collins

Mechanical Engineering Undergraduate Honors Theses

According to the CDC, atrial fibrillation is responsible for more than 454,000 hospitalizations and approximately 158,000 deaths per year. A common treatment for atrial fibrillation is catheter ablation, a process in which a long flexible tube is guided through the femoral artery and to the source of arrhythmia in the heart, where it measures the electrical potential at various locations and converts problematic heart tissue to scar tissue via ablation. This paper details the design and control of a low-cost ($400) peristaltic pump system using repetitive control to replicate blood pressure in the left atrium in a conductive ...


App Development For Wearable Sensors, Connor Pittman, Christopher Chappie, Patrick A. Tetreault Apr 2021

App Development For Wearable Sensors, Connor Pittman, Christopher Chappie, Patrick A. Tetreault

Thinking Matters Symposium

The objective of this research project was to create a wearable device that monitors bodily functions for the user to view on their smartphone. Sensor data is processed using the Arduino Nano 33 BLE microcontroller. The sensors used in this project include: proximity, temperature, humidity, heart rate, pressure, and skin impedance. This project takes advantage of the Arduino's Bluetooth low energy (BLE) capabilities so that all the data can be transmitted to a smartphone. This presentation shows the challenges faced during the project and how they were overcome. Some of these challenges include: programming, how heart rate sensors work ...


2021- The Twenty-Fifth Annual Symposium Of Student Scholars Apr 2021

2021- The Twenty-Fifth Annual Symposium Of Student Scholars

Symposium of Student Scholars Program Books

The full program book from the Twenty-fifth Annual Symposium of Student Scholars, held on April 29, 2021. Includes abstracts from the presentations and posters.


The Radx Tech Test Verification Core And The Acme Poct In The Evaluation Of Covid-19 Testing Devices: A Model For Progress And Change, Eric J. Nehl, Karl J. Simin, Nathaniel Hafer, David D. Mcmanus Apr 2021

The Radx Tech Test Verification Core And The Acme Poct In The Evaluation Of Covid-19 Testing Devices: A Model For Progress And Change, Eric J. Nehl, Karl J. Simin, Nathaniel Hafer, David D. Mcmanus

Open Access Publications by UMMS Authors

Faced with the COVID-19 pandemic, the US system for developing and testing technologies was challenged in unparalleled ways. This article describes the multi-institutional, transdisciplinary team of the “RADx SM Tech Test Verification Core” and its role in expediting evaluations of COVID-19 testing devices. Expertise related to aspects of diagnostic testing was coordinated to evaluate testing devices with the goal of significantly expanding the ability to mass screen Americans to preserve lives and facilitate the safe return to work and school. Focal points included: laboratory and clinical device evaluation of the limit of viral detection, sensitivity, and specificity of devices in ...


The Radx Tech Clinical Studies Core: A Model For Academic Based Clinical Studies, Laura L. Gibson, Nisha M. Fahey, Nathaniel Hafer, John P. Broach, Bruce A. Barton, Stephenie C. Lemon, Allison Blodgett, David D. Mcmanus Apr 2021

The Radx Tech Clinical Studies Core: A Model For Academic Based Clinical Studies, Laura L. Gibson, Nisha M. Fahey, Nathaniel Hafer, John P. Broach, Bruce A. Barton, Stephenie C. Lemon, Allison Blodgett, David D. Mcmanus

Open Access Publications by UMMS Authors

The National Institutes of Health (NIH) launched the Rapid Acceleration of Diagnostics (RADx SM ) Tech initiative to support the development and commercialization of novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) point-of-care test devices. The primary objective of the Clinical Studies Core (CSC) was to perform SARS-CoV-2 device studies involving diverse populations and settings. Within a few months, the infrastructure for clinical studies was developed, including a master protocol, digital study platform, data management system, single IRB, and multi-site partnerships. Data from some studies are being used to support Emergency Use Authorization of novel SARS-CoV-2 test devices. The CSC reduced ...


The Clinical Review Committee: Impact Of The Development Of In Vitro Diagnostic Tests For Sars-Cov-2 Within Radx Tech, Matthew L. Robinson, Laura L. Gibson, David D. Mcmanus Apr 2021

The Clinical Review Committee: Impact Of The Development Of In Vitro Diagnostic Tests For Sars-Cov-2 Within Radx Tech, Matthew L. Robinson, Laura L. Gibson, David D. Mcmanus

Open Access Publications by UMMS Authors

The NIH Rapid Acceleration of Diagnostics (RADx SM ) Tech Program was created to speed the development, validation, and commercialization of innovative point-of-care (POC) and home-based tests, and to improve clinical laboratory tests, that can directly detect SARS-CoV-2. Leveraging the experience of the Point-of-Care Technologies Research Network, a Clinical Review Committee (CRC) composed of clinicians, bioengineers, regulatory experts, and laboratorians was created to provide structured feedback to SARS-CoV-2 diagnostic innovators. The CRC convened 53 meetings with 49 companies offering SARS-CoV-2 tests in POC and reference laboratory formats as well as collection materials. The CRC identified common barriers to device design finalization ...


Quantitative Analysis Of Research On Artificial Intelligence In Retinopathy Of Prematurity, Ranjana Agrawal, Manasi Anup Agrawal, Sucheta Kulkarni, Ketan Kotecha, Rahee Walambe Apr 2021

Quantitative Analysis Of Research On Artificial Intelligence In Retinopathy Of Prematurity, Ranjana Agrawal, Manasi Anup Agrawal, Sucheta Kulkarni, Ketan Kotecha, Rahee Walambe

Library Philosophy and Practice (e-journal)

Retinopathy of Prematurity (ROP) is a disease of the eye and a potential source of blindness in low birth weight preterm infants. It is preventable if diagnosed and treated on time. Artificial Intelligence (AI) has played an important role in developing automated screening systems to assist medical experts. There are many traditional literature review articles available that focus on the scientific content of ROP-AI. The researchers also require a bibliometric analysis to become acquainted with the competing groups and new trends in this field. This paper gives a brief overview of ROP and AI systems for ROP screening with a ...


Catechol-Containing Copolymers As An Active Ingredient For Denture Adhesives, Vincent Ying Wun Kong Apr 2021

Catechol-Containing Copolymers As An Active Ingredient For Denture Adhesives, Vincent Ying Wun Kong

Electronic Thesis and Dissertation Repository

Moisture inside the mouth adds challenge to making denture adhesives formulations. Some formulations have zinc to enhance adhesion on wet skin despite knowing the health hazards. Inspired by mussel foot proteins’ catechol unit’s strong underwater adhesion, nine catechol-containing copolymers (P1A-P3C) were synthesized by free radical polymerization of 3,4-dimethoxystyrene (3,4- DMS) with different styrene derivatives followed by deprotection. P1A-P3C were used to make Fn(P)-C-PBS denture adhesive formulations which had suitable shear stresses around ≥ 5 kPa satisfying ISO 10873. In-situ NMR studies of free radical polymerization of 3,4 - DMS and styrene derivatives allowed computation of their ...


Handling And Manipulation Of Water- And Air- Borne Biological Samples Using Liquid-Infused Surfaces, Daniel P. Regan Apr 2021

Handling And Manipulation Of Water- And Air- Borne Biological Samples Using Liquid-Infused Surfaces, Daniel P. Regan

Electronic Theses and Dissertations

Research on novel materials to handling water- and airborne samples for biological threats analysis is in great demand due to the COVID-19 pandemic. Work conducted on a new field of material science, called liquid-infused surfaces, demonstrate strong potential for the handling and manipulation of biological samples. As a result of the field’s infancy, only a limited number of studies have explored how liquid-infused surfaces can apply droplet manipulation strategies to address real-world problems. Presented in this dissertation are two platforms that leverage liquid-infused surfaces to address the challenges associated with handling water- and airborne biological samples. When dealing with ...


Surface-Eroding Drug Delivery Films For Sequential And/Or Intermittent Release Of Psychoactive Drugs, Jason Price Apr 2021

Surface-Eroding Drug Delivery Films For Sequential And/Or Intermittent Release Of Psychoactive Drugs, Jason Price

Honors Theses

ABSTRACT JASON BLAKE PRICE: Surface-Eroding Drug Delivery Films for Sequential and/or

Intermittent Release of Psychoactive Drugs For patients with psychiatric diseases, adherence to medication schedules, medication

errors, and abuse are common issues. Promising new forms of therapy for these patients, such as micro-dosed lysergic acid diethylamide (LSD), where patients receive 10-20% of a full dose every third day, present further drug delivery challenges. Sequential or intermittent release of drugs from an implanted device could ensure long-term drug compliance, automate drug dosing during the life of the implant, and eliminate potential for abuse and medication errors. To this end, we ...


Full Issue Apr 2021

Full Issue

Papers & Publications: Interdisciplinary Journal of Undergraduate Research

Complete issue of Papers & Publications, Volume 8.


Call For Papers, Leigh Dillard Apr 2021

Call For Papers, Leigh Dillard

Papers & Publications: Interdisciplinary Journal of Undergraduate Research

Call for Papers


Forematter, Leigh Dillard Apr 2021

Forematter, Leigh Dillard

Papers & Publications: Interdisciplinary Journal of Undergraduate Research

Forematter


"Inclusive Inquiry." 14th Annual Research Week: Event Proceedings, University Of The Incarnate Word Apr 2021

"Inclusive Inquiry." 14th Annual Research Week: Event Proceedings, University Of The Incarnate Word

Research Week Archived Proceedings

Presentations of completed and ongoing research activity conducted by graduate and undergraduate students and faculty at University of the Incarnate Word. Coordinated and presented by the Office of Research and Graduate Studies.


A Multi-Institutional Partnership Catalyzing The Commercialization Of Medical Devices And Biotechnology Products., Nathaniel Hafer, Bryan Buchholz, Denise Dunlap, Brennan Fournier, Scott Latham, Mary Ann Picard, Steven Tello, Laura L. Gibson, Craig M. Lilly, David D. Mcmanus Apr 2021

A Multi-Institutional Partnership Catalyzing The Commercialization Of Medical Devices And Biotechnology Products., Nathaniel Hafer, Bryan Buchholz, Denise Dunlap, Brennan Fournier, Scott Latham, Mary Ann Picard, Steven Tello, Laura L. Gibson, Craig M. Lilly, David D. Mcmanus

COVID-19 Publications by UMMS Authors

The commercialization of medical devices and biotechnology products is characterized by high failure rates and long development lead times particularly among start-up enterprises. To increase the success rate of these high-risk ventures, the University of Massachusetts Lowell (UML) and University of Massachusetts Medical School (UMMS) partnered to create key academic support centers with programs to accelerate entrepreneurship and innovation in this industry. In 2008, UML and UMMS founded the Massachusetts Medical Device Development Center (M2D2), which is a business and technology incubator that provides business planning, product prototyping, laboratory services, access to clinical testing, and ecosystem networking to medical device ...


Preservation Of Morehead State History, Jacob Bush Apr 2021

Preservation Of Morehead State History, Jacob Bush

2021 Celebration of Student Scholarship - Oral Presentations

This project is being undertaken in an effort to preserve the buildings and history of Morehead State University. It is the goal of this project to make additions to the historic district of MSU by adding qualifying buildings to the National Register of Historic Places. By adding buildings to the Register, they would be recognized on the federal level as historic sites and receive support for their preservation. The Register seeks to protect sites of importance through many ways including the gifting of funding to ensure preservation. The goals of this project will be achieved using historical texts from our ...


Catalogue Of Lichen Species In The Rowan County Sphagnum Swamp, Rowan County, Kentucky, Deanna Kidd, Allen Risk Apr 2021

Catalogue Of Lichen Species In The Rowan County Sphagnum Swamp, Rowan County, Kentucky, Deanna Kidd, Allen Risk

2021 Celebration of Student Scholarship - Poster Presentations

Rowan County Sphagnum Swamp is one of the best remaining examples of a bottomland swamp forest left in the Knobs region of Kentucky. Bottomland swamp forests are characterized by soil with a high percentage of organic matter above clay and Devonian shale. This arrangement leads to standing water much of the year and a strongly acidic soil. Common tree species in the Rowan County Sphagnum Swamp include Acer rubrum (red maple), Quercus palustris (pin oak), Liquidambar styraciflua (sweet gum), Nyssa sylvatica (sour gum) and Betula nigra (river birch). Bottomland swamp forests used to be more common, but have dwindled due ...


Analytical Method Development For The Analysis Of Biomass Degradation Products, Calista Dean, Emma Schmittzehe Apr 2021

Analytical Method Development For The Analysis Of Biomass Degradation Products, Calista Dean, Emma Schmittzehe

2021 Celebration of Student Scholarship - Poster Presentations

The goal of this project is to study the kinetics of hydrothermal liquefaction of biomass. Biomass contains stored chemical energy that can be converted to renewable liquid and gaseous fuels through various processes, but an in-depth understanding of the kinetics of these processes is important in order for them to be feasible on a large scale. Since biomass degradation products depend on the type of biomass used as well as the reaction conditions, this task can be quite complicated. To minimize complications in our initial studies, we will use D-glucose as the starting material. To better understand the degradation pathway ...


Through The Eye Of The Beholder: Student Teaching In Kentucky During A Pandemic, Brittany Stidham, Kimberely Nettleton, Sandra Riegle Apr 2021

Through The Eye Of The Beholder: Student Teaching In Kentucky During A Pandemic, Brittany Stidham, Kimberely Nettleton, Sandra Riegle

2021 Celebration of Student Scholarship - Poster Presentations

Student teaching is the capstone of student teaching preparation. The Covid-19 pandemic has changed many aspects of student teaching; and students have had to adapt to a new way of both learning and teaching. As the world turned upside down, student teachers were expected to interact with their students and provide instruction. The pandemic caused student teachers to develop new ways to engage lessons and hold conversations in a virtual environment. This pilot study examines the ways in which a small group of student teachers in eastern Kentucky internalized their experience.


The Effects Of Nurse's Mental Health On Quality Patient Outcomes: A Quality Improvement Study, Alexandria Kincaid, Mara Walker, Mila Osborne, Tiyanna Jones, Victoria Clevenger, Suzi White Apr 2021

The Effects Of Nurse's Mental Health On Quality Patient Outcomes: A Quality Improvement Study, Alexandria Kincaid, Mara Walker, Mila Osborne, Tiyanna Jones, Victoria Clevenger, Suzi White

2021 Celebration of Student Scholarship - Poster Presentations

Morale among nurses is declining rapidly, this could be due to the rising mental illnesses like anxiety, depression, chronic fatigue, stress, worry and post-traumatic stress disorder. Not to mention the rate of suicide in female nurses is 11.97/ 100,000 compared to non-nurse females having a rate of 7.58/ 100,000. Also, male nurses have an incidence of suicide at a rate of 39.8/ 100,000 compared to non-nurse males at 28.2/ 100,000. A thorough literature review was conducted and a total of 40 studies were reviewed. Common themes that emerged were "A decrease in ...


Preliminary Study On Beetle Biodiversity And Its Role As A Metric For Ecosystem Heterogeneity In The Rowan County Area, Belinda Candra, Sara Monfalcone, Charles Lydeard, Sean O'Keefe Apr 2021

Preliminary Study On Beetle Biodiversity And Its Role As A Metric For Ecosystem Heterogeneity In The Rowan County Area, Belinda Candra, Sara Monfalcone, Charles Lydeard, Sean O'Keefe

2021 Celebration of Student Scholarship - Poster Presentations

Biodiversity is important for maintaining ecosystem function, including the adaptation of the organisms to reflect the change in the ecological community. Many ecological roles are performed by insects, including keystone organisms, ecosystem engineers and soil modifiers, part of the food chain, general symbionts, and pollinators, and creating a cumulative database of the variety of insect types allows for an effective overview of the different aspects of the environment from which samples are collected. With approximately 400,000 described species, beetles are immensely diverse in their lifestyles and ecological roles, thus making them valuable tools in environmental assessments of terrestrial and ...


Evidence Based Evaluation Of A Ventilator Management Clinical Practice Protocol, Kyle Mills, Michelle Mcclave Apr 2021

Evidence Based Evaluation Of A Ventilator Management Clinical Practice Protocol, Kyle Mills, Michelle Mcclave

2021 Celebration of Student Scholarship - Poster Presentations

Nursing care and management of mechanically ventilated patients requires specific care elements to be achieved in order for optimal patient outcomes. The ventilator management policy guides nursing care for this select group of patients. The ventilator management policy of a rural community acute healthcare facility was evaluated for evidence-base and validity using the AGREE GRS rating scale. The evaluation process included interview of the director of the inpatient unit responsible for care of ventilator patients, as well as review of the most current evidence-based practice protocols. Evaluation results indicate the facility’s policy met the needs of the patients, and ...