Physical Sciences and Mathematics Commons^™

The Energy Of Interval-Valued Complex Neutrosophic Graph Structures: Framework, Application And Future Research Directions, S.N. Suber Bathusha, Sowndharya Jayakumar, S. Angelin Kavitha Raj

Neutrosophic Systems with Applications

Graph structure is a developing field with many real-world applications and advancements, particularly effective frameworks for integrative problem-solving in computer networks and artificial intelligence systems. To define the idea of an Interval-Valued Complex Neutrosophic Graph Structure (IVCNGS), the concept of an Interval-Valued Complex Neutrosophic Set (IVCNS) is applied to the graph structure. Using the adjacency matrix to calculate the degree of vertex, we have defined some findings about the IVCNGS. Further, we compute the energy and Laplacian energy of IVCNGS. Moreover, we derive the lower and upper bounds for the energy and Laplacian energy of IVCNGS, and we have discussed …

Internal Parametricity, Without An Interval, Thorsten Altenkirch, Yorgo Chamoun, Ambrus Kaposi, Michael Shulman

Mathematics: Faculty Scholarship

Parametricity is a property of the syntax of type theory implying, e.g., that there is only one function having the type of the polymorphic identity function. Parametricity is usually proven externally, and does not hold internally. Internalising it is difficult because once there is a term witnessing parametricity, it also has to be parametric itself and this results in the appearance of higher dimensional cubes. In previous theories with internal parametricity, either an explicit syntax for higher cubes is present or the theory is extended with a new sort for the interval. In this paper we present a type theory …

Final 2023 Butte Priority Soils Operable Unit Type B Borrow Material Submittal #1, Pioneer Technical Services, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Young Professionals: Fireside Chat With Jacques Lewiner And J. Keith Nelson At The Ieee Conference On Electrical Insulation And Dielectric Phenomena, Mattewos Tefferi, Allen Andersen, Sneha Hedge, Moein Borghei

Journal Articles

At the IEEE Conference on Electrical Insulation and Dielectric Phenomena (CEIDP), the Dielectrics and Electrical Insulation Society’s Young Professionals (DEIS-YP) Committee has initiated a YP luncheon event. This event aims to feature keynote speakers who share insights into their career trajectories with young professionals. In the current CEIDP edition, we had the privilege of hosting two distinguished speakers: Jacques Lewiner, the 2023 Whitehead Memorial Lecturer, and J. Keith Nelson, the 2022 recipient of the Dakin Award who also presented his award lecture at the CEIDP 2023. The fire- side chat was moderated by Allen Andersen, who began with initial questions …

Questioning Reality: The Progressive Development Of Modern Physics, Joshua Lancman

STEM for Success Showcase

Humanity has a tendency to divide time. The past is distinct from the present which is entirely separate from the future. In supposedly 20-20 vision history is neatly divided into different sections, distinct eras with sharp lines between them. What is present and in the future is always modern. What is past is something else with another name.

Yet time is not divided so neatly. We know this living through it: years and decades blend into one another in a non-uniform progression. To divide human history into separate eras is a necessary simplification, as it helps to ascribe order onto …

Gwtc-2.1: Deep Extended Catalog Of Compact Binary Coalescences Observed By Ligo And Virgo During The First Half Of The Third Observing Run, R. Abbott, T. D. Abbott, F. Acernese, K. Ackley, Teviet Creighton, Mario C. Diaz, Francisco Llamas, Soma Mukherjee, Volker Quetschke, Wenhui Wang

Physics & Astronomy Faculty Publications

The second Gravitational-Wave Transient Catalog, GWTC-2, reported on 39 compact binary coalescences observed by the Advanced LIGO and Advanced Virgo detectors between 1 April 2019 15∶00 UTC and 1 October 2019 15∶00 UTC. Here, we present GWTC-2.1, which reports on a deeper list of candidate events observed over the same period. We analyze the final version of the strain data over this period with improved calibration and better subtraction of excess noise, which has been publicly released. We employ three matched-filter search pipelines for candidate identification, and estimate the probability of astrophysical origin for each candidate event. While GWTC-2 used …

Stemdriver: A Knowledgebase Of Gene Functions For Hematopoietic Stem Cell Fate Determination, Kexin Huang, Yang Liu, Grant Wang, Ruihan Luo, Ting Niu, Yuzhou Feng, Haixia Xu, Pora Kim, Xiaobo Zhou

Faculty, Staff and Student Publications

StemDriver is a comprehensive knowledgebase dedicated to the functional annotation of genes participating in the determination of hematopoietic stem cell fate, available at http://biomedbdc.wchscu.cn/StemDriver/. By utilizing single-cell RNA sequencing data, StemDriver has successfully assembled a comprehensive lineage map of hematopoiesis, capturing the entire continuum from the initial formation of hematopoietic stem cells to the fully developed mature cells. Extensive exploration and characterization were conducted on gene expression features corresponding to each lineage commitment. At the current version, StemDriver integrates data from 42 studies, encompassing a diverse range of 14 tissue types spanning from the embryonic phase to adulthood. In order …

Fusionpdb:: A Knowledgebase Of Human Fusion Proteins

Faculty, Staff and Student Publications

Tumorigenic functions due to the formation of fusion genes have been targeted for cancer therapeutics (i.e. kinase inhibitors). However, many fusion proteins involved in various cellular processes have not been studied for targeted therapeutics. This is because the lack of complete fusion protein sequences and their whole 3D structures has made it challenging to develop new therapeutic strategies. To fill these critical gaps, we developed a computational pipeline and a resource of human fusion proteins named FusionPDB, available at https://compbio.uth.edu/FusionPDB. FusionPDB is organized into four levels: 43K fusion protein sequences (14.7K in-frame fusion genes, Level 1), over 2300 + 1267 …

Ageannomo: A Knowledgebase Of Multi-Omics Annotation For Animal Aging, Haixia Xu, Qingxuan Li, Yuhao Jia, Liyu Huang, Pora Kim, Xiaobo Zhou

Faculty, Staff and Student Publications

Aging entails gradual functional decline influenced by interconnected factors. Multiple hallmarks proposed as common and conserved underlying denominators of aging on the molecular, cellular and systemic levels across multiple species. Thus, understanding the function of aging hallmarks and their relationships across species can facilitate the translation of anti-aging drug development from model organisms to humans. Here, we built AgeAnnoMO (https://relab.xidian.edu.cn/AgeAnnoMO/#/), a knowledgebase of multi-omics annotation for animal aging. AgeAnnoMO encompasses an extensive collection of 136 datasets from eight modalities, encompassing 8596 samples from 50 representative species, making it a comprehensive resource for aging and longevity research. AgeAnnoMO characterizes …

Fusionneoantigen: : A Resource Of Fusion Gene-Specific Neoantigens, Xiaobo Zhou, Pora Kim

Faculty, Staff and Student Publications

Among the diverse sources of neoantigens (i.e. single-nucleotide variants (SNVs), insertions or deletions (Indels) and fusion genes), fusion gene-derived neoantigens are generally more immunogenic, have multiple targets per mutation and are more widely distributed across various cancer types. Therefore, fusion gene-derived neoantigens are a potential source of highly immunogenic neoantigens and hold great promise for cancer immunotherapy. However, the lack of fusion protein sequence resources and knowledge prevents this application. We introduce 'FusionNeoAntigen', a dedicated resource for fusion-specific neoantigens, accessible at https://compbio.uth.edu/FusionNeoAntigen. In this resource, we provide fusion gene breakpoint crossing neoantigens focused on ∼43K fusion proteins of ∼16K in-frame …

Cov2var, A Function Annotation Database Of Sars-Cov-2 Genetic Variation, Jianguo Wen, Weiling Zhao, Pora Kim, Xiaobo Zhou

Faculty, Staff and Student Publications

The COVID-19 pandemic, caused by the coronavirus SARS-CoV-2, has resulted in the loss of millions of lives and severe global economic consequences. Every time SARS-CoV-2 replicates, the viruses acquire new mutations in their genomes. Mutations in SARS-CoV-2 genomes led to increased transmissibility, severe disease outcomes, evasion of the immune response, changes in clinical manifestations and reducing the efficacy of vaccines or treatments. To date, the multiple resources provide lists of detected mutations without key functional annotations. There is a lack of research examining the relationship between mutations and various factors such as disease severity, pathogenicity, patient age, patient gender, cross-species …

Drmref: Comprehensive Reference Map Of Drug Resistance Mechanisms In Human Cancer, Kexin Huang, Jiajia Liu, Grant Wang, Pora Kim, Qianqian Song, Xiaobo Zhou

Faculty, Staff and Student Publications

Drug resistance poses a significant challenge in cancer treatment. Despite the initial effectiveness of therapies such as chemotherapy, targeted therapy and immunotherapy, many patients eventually develop resistance. To gain deep insights into the underlying mechanisms, single-cell profiling has been performed to interrogate drug resistance at cell level. Herein, we have built the DRMref database (https://ccsm.uth.edu/DRMref/) to provide comprehensive characterization of drug resistance using single-cell data from drug treatment settings. The current version of DRMref includes 42 single-cell datasets from 30 studies, covering 382 samples, 13 major cancer types, 26 cancer subtypes, 35 treatment regimens and 42 drugs. All datasets in …

Synchronicity: An Analysis Of Einstein's Halfway Rule, Preslava Nikolova

Rushton Journal of Undergraduate Humanities Research

For the modern world to function, Global Positioning System satellites must synchronize to clocks on Earth. This paper examines a concept that underlies GPS systems, namely Albert Einstein’s halfway rule—the idea that a line of simultaneity exists between two events in different systems. This essay discusses how Einstein used conventionalist methods to establish ½ as a constant value for σ to take advantage of the property of symmetry.

Differential Equations For A Changing World:How To Engage Students In Learning And Applying Differential Equations, Biyong Luo

CODEE Journal

In this article, I share my decade-long experience teaching an intensive five-week summer Differential Equation course covering complex topics and tips for creating an interactive and supportive learning environment to optimize student engagement. This article provides my detailed approach to planning and teaching an asynchronous course with rigor and flexibility for each student. An interactive teaching approach and variety of learning activities will augment students’ mathematical fluency and appreciation of the importance of differential equations in modeling a wide variety of real-world situations with special attention to ways differential equations can be relevant to creating public policy.

Odes And Mandatory Voting, Christoph Borgers, Natasa Dragovic, Anna Haensch, Arkadz Kirshtein, Lilla Orr

CODEE Journal

This paper presents mathematics relevant to the question whether voting should be mandatory. Assuming a static distribution of voters’ political beliefs, we model how politicians might adjust their positions to raise their share of the vote. Various scenarios can be explored using our app at https: //centrism.streamlit.app/. Abstentions are found to have great impact on the dynamics of candidates, and in particular to introduce the possibility of discontinuous jumps in optimal candidate positions. This is an unusual application of ODEs. We hope that it might help engage some students who may find it harder to connect with the more customary …

2024 January 4 - Tennessee Weekly Drought Summary, Tennessee Climate Office, East Tennessee State University

Tennessee Climate Office Weekly Drought Summaries

No abstract provided.

Investigation Of Earthquake Sequence And Stress Transfer In The Eastern Anatolia Fault Zone By Coulomb Stress Analysis, Hamdi̇ Alkan, Aydin Büyüksaraç, Özcan Bektaş

Turkish Journal of Earth Sciences

A devastating earthquake with a magnitude of (Mw = 7.7) occurred on February 06, 2023, in the Pazarcık segment of the Eastern Anatolian Fault Zone, which has not shown major earthquake activity for a long time. On the same day, another earthquake with a magnitude of (Mw = 7.6) occurred in Ekinözü-Elbistan (Kahramanmaraş) in the northwest. Three more earthquakes with magnitudes of Mw = 6.6, Mw = 5.9, and ML = 5.7 occurred on the same day, and significant damage, loss of life, and property occurred in 11 provinces and districts. A sixth earthquake occurred with Mw = 6.4 magnitude …

Ode Models Of Wealth Concentration And Taxation, Bruce Boghosian, Christoph Borgers

CODEE Journal

We refer to an individual holding a non-negligible fraction of the country’s total wealth as an oligarch. We explain how a model due to Boghosian et al. can be used to explore the effects of taxation on the emergence of oligarchs. The model suggests that oligarchs will emerge when wealth taxation is below a certain threshold, not when it is above the threshold. The underlying mechanism is a transcritical bifurcation. The model also suggests that taxation of income and capital gains alone cannot prevent the emergence of oligarchs. We suggest several opportunities for students to explore modifications of the model.

Approved Butte Priority Soils Operable Unit (Bpsou) Unreclaimed And Insufficiently Reclaimed Sites Request For Information 2022-01, Mike Mcanulty

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Fitting A Covid-19 Model Incorporating Senses Of Safety And Caution To Local Data From Spartanburg County, South Carolina, D. Chloe Griffin, Amanda Mangum

CODEE Journal

Common mechanistic models include Susceptible-Infected-Removed (SIR) and Susceptible-Exposed-Infected-Removed (SEIR) models. These models in their basic forms have generally failed to capture the nature of the COVID-19 pandemic's multiple waves and do not take into account public policies such as social distancing, mask mandates, and the ``Stay-at-Home'' orders implemented in early 2020. While the Susceptible-Vaccinated-Infected-Recovered-Deceased (SVIRD) model only adds two more compartments to the SIR model, the inclusion of time-dependent parameters allows for the model to better capture the first two waves of the COVID-19 pandemic when surveillance testing was common practice for a large portion of the population. We find …

Raising Student Awareness Of Environmental Issues Via Writing Assignments With Differential Equations, Michelle L. Ghrist

CODEE Journal

In this paper, I discuss two environmentally-focused writing assignments that I developed and implemented in recent integral calculus and differential equations courses. These models of carbon storage and PCB’s in a river provide interesting applications of one-compartment mixing problems. The assignments were intended to focus student attention on sustainability concerns while also developing other essential skills. I discuss these assignments and their effect on my students’ technical writing and environmental awareness. Detailed introductory instructions and mostly complete solutions to these assignments appear in the appendices, to include sample student work.

Modeling Aircraft Takeoffs, Catherine Cavagnaro

CODEE Journal

Real-world applications can demonstrate how mathematical models describe and provide insight into familiar physical systems. In this paper, we apply techniques from a first-semester differential equations course that shed light on a problem from aviation. In particular, we construct several differential equations that model the distance that an aircraft requires to become airborne. A popular thumb rule that pilots have used for decades appears to emanate from one of these models. We will see that this rule does not follow from a representative model and suggest a better method of ensuring safety during takeoff. Aircraft safety is definitely a matter …

Preliminary Results Of The Great Kahramanmaraş 6 February 2023 Earthquakes (Mw 7.7 And 7.6) And 20 February 2023 Antakya Earthquake (Mw 6.4), Eastern Türkiye, Şule Gürboğa, Önder Kayadi̇bi̇, Hafi̇ze Akilli, Serap Arikan, Sevi̇lay Tan

Turkish Journal of Earth Sciences

The first MW 7.7 and second MW 7.6 Kahramanmaraş earthquakes were the strongest tectonic events in Eastern Türkiye since the MW 7.9 Erzincan earthquake in 1939. The first and second events occurred on the Pazarcık and Çardak segments of the East Anatolian Fault System, respectively. A subsequent significant earthquake of MW 6.4 occurred in the Antakya fault zone. We summarize preliminary earthquake data and share our previous field observations to better understand the mechanism and provide scientific consequences for future investigations and layout planning. After combining the field observations, kinematic analysis of fault surfaces, investigations of orthophotos, characteristics of mainshocks, …

Surface Rupture During The 6th Of February 2023 Mw 7.6 Elbistan-Ekinözü (Kahramanmaraş) Earthquake: Implications For Fault Rupture Dynamics Along The Northern Branch Of East Anatolian Fault Zone, Mustafa Softa, Fi̇kret Koçbulut, Eli̇f Akgün, Ercan Aksoy, Hasan Sözbi̇li̇r, Orhan Tatar, Volkan Karabacak, Çağlar Özkaymak, Mehmet Utku, Özkan Cevdet Özdağ, Recep Çakir, Ahmet Demi̇r, Gökhan Arslan

Turkish Journal of Earth Sciences

On the 6th of February 2023, Mw 7.7 Pazarcık (Kahramanmaraş) and Mw 7.6 Ekinözü (Kahramanmaraş) earthquakes that occurred in Türkiye are devastating earthquake series that filled the existing seismic gaps on East Anatolian Fault Zone on the same day. The first Mw 7.7 earthquake caught most people in their sleep and 9 h later, a second one was triggered, ending up with more than 50k death toll, widespread damage to buildings, and massive landslides. This study presents the surface rupture geometry and coseismic displacement characteristics determined with field observations immediately after February 6, 2023, Ekinözü (Kahramanmaraş, Türkiye) earthquake (Mw 7.6). …

Tepehan Rockslide: A Large-Scale Earthquake-Induced Geological Structure Formed By Mw:7.8 Kahramanmaraş (Pazarcık) Earthquake, Türkiye, Ökmen Sümer

Turkish Journal of Earth Sciences

Three devastating and powerful earthquakes hit the southeastern and eastern parts of Turkey and the northestern part of Syria in February of 2023, causing many earthquake-induced slope movements. One of these major mass movements is called the “Tepehan Rockslide”, which was formed by the first Mw: 7.8 earthquake on February 6th, 2023 at Pazarcık (Kahramanmaraş) located in the Altınözü district of Hatay province. The rockslide involved the movement of Middle Miocene basement rocks that consist of clayey limestone, marl, and fine-grained clastic sedimentary rocks. The morphogenetic evaluation of the structure reveals that the Tepehan Rockslide is a very rapidly developed …

Response Of Water Resources To The Kahramanmaraş Earthquakes (Mw 7.7 And Mw 7.6) That Occurred On February 6, 2023, On The East Anatolian Fault Zone (Türkiye), Celaletti̇n Şi̇mşek, Görkem Akinci, Okan Fistikoğlu, Kerem Canli, Hasan Sözbi̇li̇r, Azi̇ze Ayol, Efem Bi̇lgi̇ç

Turkish Journal of Earth Sciences

On February 6, 2023, two destructive earthquakes of 7.7 MW and 7.6 MW occurred in Pazarcık (Kahramanmaraş) and Elbistan (Kahramanmaraş) at 04:17 and 13:24 hours, respectively. These earthquakes caused a surface rupture with a total length of 450 km in the region with an average displacement of 3 m between the Arabian and Anatolian plates. This study was conducted to investigate the physical deformation of the aquifer system and the current water quality characteristics in the affected region utilizing field observations and on-site analysis of water sources and tap water. The study revealed significant physical changes in the karstic springs …

Soil Liquefaction And Subsidence Disaster In İskenderun Related To The 6 February 2023 Pazarcık (Mw: 7.7) And 20 February Defne (Mw: 6.4) Earthquakes, Türkiye, Hüseyi̇n Öztürk, Craig A. Davis, İbrahi̇m Kuşku, Süleyman Dalğiç, Cem Kasapçi, Muharrem Alper Şengül

Turkish Journal of Earth Sciences

The Mw 7.7 Pazarcık earthquake on February 06, 2023, struck southern Türkiye, causing typical liquefaction along the shores of İskenderun Bay. This liquefaction was characterized by lateral spreading, subsidence, and flooding. Subsidence-triggered sand ejecta, water flows, and opening cracks were identified in areas spanning approximately 2 km in length and 300 m in width. Based on coastal references such as lighthouses or harbor platforms, settlements of 0.8 m and lateral spreading of 0.4% were recorded along the coastal zone following the Pazarcık earthquake. According to camera recordings, liquefaction-related water and silty sand outflows occurred 29 min after the earthquake. The …

Blue Whale And Krill Populations Modeling, Li Zhang

CODEE Journal

We present an intriguing topic in an undergraduate mathematical modeling course where predator-prey models are taught to our students. We describe modeling activities and the use of technology that can be implemented in teaching this topic. Through modeling activities, students are expected to use the numerical and graphical methods to observe the qualitative long-term behavior of predator and prey populations. Although there are other choices of predators and prey, we find that using blue whales and krill as predator and prey, respectively, would be most beneficial in strengthening our students' awareness of protecting endangered species and its impact on climate …

Nonlinear Dynamics Of Mountain Pine Beetle Populations: Discussion Of Forestry Policy, A Survey Of Existing Mathematical Models, And Code Base Demonstration, Scott A. Strong, Maya Maes-Johnson

CODEE Journal

This article presents existing mathematical models associated with mountain pine beetle populations in lodgepole pine forests, whose reproductive cycle requires the destruction of colonized host trees, decreasing timber availability/quality, and providing fuel sources for wildfires. With the existence of a positive-feedback loop with environmental warming, the need for intervention and management is clear. However, the legislative responses to the focusing events from our 2000-2010 North American epidemics are characterized as under-leveraged. While the reasons for this are multifaceted, increasing the capacity of STEM-informed individuals to take part in quantitative modeling of the underlying ecosystem generates awareness and provides pathways connecting …

Applying The Sir Model: Can Students Advise The Mayor Of A Small Community?, Carrin Goosen, Mark I. Nelson, Mahime Watanabe

CODEE Journal

This is an account of a modelling scenario that uses the sir epidemic model. It was used in a third year applied mathematics subject. All students were enrolled in a mathematics degree of some type. Students are presented with the results of a test carried out on 100 individuals in a community containing 3000 people. From this they determined the number of infectious and recovered individuals in the population. Given the per capita recovery rate and making a suitable assumption about the number of infectious individuals at the start of the epidemic, they then estimate the infectious contact rate and …