Physical Sciences and Mathematics Commons^™

Machine Learning-Enabled Chemical Ecology For Integrated Pest Management: From Volatiles To Field Applications, Steve B.S. Baleba, Victor O. Omondi, Pascal Aigbedion-Atalor, Emmanuel Peter, Souleymane Diallo, Komi Mensah Agboka

All Peer-Reviewed Publications

Machine learning is transforming chemical ecology by accelerating the discovery and deployment of semiochemical-based tools for precision pest management. These advances are particularly important in the face of climate change, pesticide resistance, and the growing need for sustainable agricultural intensification. This review synthesizes how machine learning can be applied across the semiochemical discovery and implementation pipeline, from chemical signal detection to field deployment and decision support for integrated pest management. We review major machine learning approaches and demonstrate how they extract biologically relevant information from high-dimensional chemical, electrophysiological, behavioral, sensor, and field datasets. These methods accelerate semiochemical discovery, prioritize candidate …

A Visitation Grid For Complete Coverage Foraging In Robot Swarms, Arturo Gonzalez, Yifeng Gao, Li Zhang, Qi Lu

Computer Science Faculty Publications

The complete collection of sparse resources in large, unknown environments remains a challenging problem for autonomous robot swarms. Previous studies have shown that a substantial portion of total mission time is consumed during the final stage of collection, where only a small fraction of randomly scattered resources remain. Consequently, many existing swarm foraging algorithms (search and collection) focus on collecting most resources within a limited time window, rather than improving end-stage efficiency for collecting all resources. We propose a grid-based stochastic foraging strategy that explicitly reduces redundant visits and accelerates late-stage collection. The unknown search area is partitioned into a …

Long-Term Monitoring Of The Optical Performance Of The Primary Mirrors At The Coihueco And Loma Amarilla Sites Of The Pierre Auger Observatory, A. Abdul Halim, P. Abreu, M. Aglietta, M. Ahmed, I. Allekotte, K. Almeida Cheminant, B. Fick, K. Nguyen, D. Nitz, Et Al.

Michigan Tech Publications

This paper presents the results of an optical performance monitoring campaign for the primary mirrors installed in fluorescence telescopes at the Coihueco and Loma Amarilla sites at the Pierre Auger Observatory in Argentina. Since the end of 2003, this effort has developed into a unique long-term dataset that addresses the performance of the primary mirrors. We have focused on the scattering characteristics and specular reflectance of mirror segments, as well as their evolution over several years of operation. Despite being housed in climate-controlled buildings, dust accumulation, impurities, and natural aging — such as oxidation or other chemical or physical degradation …

Artificial Intelligence In Medicine: Barriers, Solutions, And Strategies, Anil Harrison, Melissa Stradley Moreno, Caroline E. Williams, Munevver Mine Subasi, Ersoy Subasi

HCA Healthcare Journal of Medicine

The integration of artificial intelligence (AI) and machine learning (ML) into health care holds the potential to revolutionize patient care by enhancing clinical decision-making, improving diagnostic accuracy, and reducing costs. Despite this promise, adoption remains limited due to a range of technical, regulatory, educational, and cultural barriers. This paper examines these challenges and proposes strategies to support safe and effective implementation of AI in clinical practice.

Key barriers include the lack of model interpretability, often referred to as the "black box" problem, which undermines clinician trust and accountability in clinical settings, evolving regulatory frameworks and unresolved questions surrounding liability, and …

Unique Combinations Of Packing Integer Squares, Keith M. Dreiling, Austin Leanna, William Mooney

SACAD: Scholarly Activities

This research investigates a function, informally named WAK(x), that describes the number of ways to divide an integer square into integer subsquares counting only the list of parts. Previous research has shown values up to 28, though finding these values is computationally complex and requires a long runtime using computer algorithms. We attempt to find patterns in the values and many aspects of the values, hoping to find a general solution. We are unsure if a solution exists, but we have ideas for how to move forward in finding a solution.

Wearable Sensor-Based Phase Segmentation Analysis Of Front Crawl Swimming: A Scoping Review, Jonathan Simoes, Samuel Aylward, Daniel Hamze, Daniel James Goble, Daniel M. Russell, Joshua Haworth

Exercise Science Faculty Publications

Front crawl swimming stroke phase segmentation has historically relied on video analysis, but the development of wearable sensor technology has created new opportunities for automated phase segmentation. This scoping review mapped the available evidence on wearable sensor-based stroke phase segmentation methods in front crawl swimming, following PRISMA-ScR guidelines. A systematic search of SPORTDiscus, Web of Science, and IEEE Xplore conducted from January to June 2026, identified 15 eligible peer-reviewed studies published between 2000 and 2024. The review revealed an emerging field of research that has converged methodologically around inertial measurement units (IMUs) and the Chollet phase segmentation framework while remaining …

The Crucial Role Of Machine Learning Models In Predicting Current Childhood Asthma: Model Comparison, Calibration, And Shap-Based Interpretation, Aditya Chakraborty, A. K.M. Raquibul Bashar

Epidemiology, Biostatistics, & Environmental Health Faculty Publications

Background: Asthma is one of the most prominent chronic diseases in children and one of the most challenging ailments to diagnose in infants and preschoolers in the United States. Predictive models can be instrumental in improving early diagnosis, personalized treatment strategies, and disease progression. By utilizing nationalized data, this study focuses on building and comparing high-performing analytical predictive models based on the relevant risk factors and identifying the most influential predictors.

Methods: We analyzed cross-sectional BRFSS Asthma Call-Back Survey data (2011-2020; N = 9,813) and randomly split participants into training and testing sets. An XGBoost model (hyperparameters tuned via grid …

Maxgrnet: A Multi-Axis Vision Transformer With Improved Generalization For Eye Disease Classification Using Explainable Ai With Insertion-Deletion Operations On Fundus Images, Md Mehedi Hasan Santo, Fuyad Hasan Bhoyan, Fuad Ibne Jashim Farhad, Fahmid Al Farid, Sovon Chakraborty, Md Humaion Kabir Mehedi, Jia Uddin, Hezerul Bin Abdul Karim

Computer Science Faculty Publications

Eye diseases, including diabetic retinopathy (DR), glaucoma, and cataracts, represent a major global health concern and can lead to severe visual impairment or blindness if not identified in a timely manner. This study proposes a novel eye disease classification framework based on a multi-axis vision transformer (MaxViT) applied to color fundus images with Explainable Artificial Intelligence (XAI) techniques to enhance model transparency. The proposed architecture integrates transformer-based attention mechanisms with Global Response Normalization (GRN)-based multi-layer perceptron (MLP) layers to capture complex spatial and contextual relationships within fundus images effectively. The model was evaluated on a publicly available eye disease classification …

Markov Chain Wave Generative Adversarial Network For Bee Bioacoustic Signal Synthesis, Kumudu Samarappuli, Iman Ardekani, Mahsa Mohaghegh, Abdolhossein Sarrafzadeh

Electrical & Computer Engineering Faculty Publications

This paper presents a framework for synthesizing bee bioacoustic signals associated with hive events. While existing approaches like WaveGAN have shown promise in audio generation, they often fail to preserve the subtle temporal and spectral features of bioacoustic signals critical for event-specific classification. The proposed method, MCWaveGAN, extends WaveGAN with a Markov Chain refinement stage, producing synthetic signals that more closely match the distribution of real bioacoustic data. Experimental results show that this method captures signal characteristics more effectively than WaveGAN alone. Furthermore, when integrated into a classifier, synthesized signals improved hive status prediction accuracy. These results highlight the potential …

Qubit Lattice Algorithm Simulations Of The Scattering Of A Bounded Two Dimensional Electromagnetic Pulse From The Infinite Planar Dielectric Interface, Min Soe, George Vahala, Linda Vahala, Efstratios Koukoutsis, Abhay K. Ram, Kyriakos Hizanidis

Electrical & Computer Engineering Faculty Publications

Qubit lattice algorithm (QLA) simulations are performed for a two-dimensional spatially bounded pulse propagating onto a plane interface between two dielectric slabs. QLA is an initial value scheme that consists of a sequence of unitary collision and streaming operators, with appropriate potential operators, that recover Maxwell equations in inhomogeneous dielectric media to the second order in the lattice discreteness. For the case of total internal reflection, there is transient energy transfer into the second medium due to the evanescent fields as the Poynting unit vector of the pulse is rotated from its incident to reflected direction. Because of the finite …

Using Automotive Lidar To Reduce The Energy Consumption Of An Ego Autonomous Vehicle, Logan P. Schexnaydre

Dissertations, Master's Theses and Master's Reports

There is significant potential to reduce the energy consumption of the transportation sector through autonomous vehicles. Prior work on autonomous vehicle energy efficiency focuses on the whole system or the control subsystem. Yet, the sensing and processing components, which have direct and indirect effects on net energy use, are less explored. This dissertation fills this gap by modeling and evaluating these effects for lidar sensors, which provide high-resolution spatial data at the cost of high power and processing demands. I apply lidar to the energy-saving tasks of automated vehicle following and road surface profiling. For automated vehicle following, I model …

Satellite-Based Identification Of Mesoscale And Submesoscale Eddies And Fronts In The Gulf Of Mexico, Ethan Cruz

Theses and Dissertations

Mesoscale and submesoscale processes in the Gulf of Mexico (GoM) are fundamental in shaping the region’s physical and biogeochemical ocean dynamics. Advances in high-resolution satellite observations now allow detailed detection of submesoscale (< 25 km radius) and mesoscale eddies and ocean fronts, which drive heat, nutrient, and carbon fluxes. This dissertation integrates two complementary investigations: (1) a comparison of eddy-tracking algorithms: Contour Tracing (CT) and Temperature Thresholding (TT), applied to Optimum Interpolation Sea Surface Temperature (OISST, 1/4°) and Operational Sea Surface Temperature and Ice Analysis (OSTIA, 1/20°) products; and (2) a comparative evaluation of three ocean front detection algorithms: Canny Edge Detection (Canny), the Cayula–Cornillon Algorithm (CCA), and the Belkin–O’Reilly Algorithm (BOA), across multiple satellite-derived parameters, including sea surface temperature (SST), sea surface salinity (SSS), chlorophyll-a (Chl-a), and altimetry-derived absolute dynamic topography (ADT). The eddy-tracking analysis shows that the higher-resolution OSTIA consistently detected more eddies than OISST, with TT performing best during winter when SST gradients were strongest. The front detection analysis, incorporating datasets from the Surface Water and Ocean Topography (SWOT) and Plankton, Aerosol, Cloud, Ocean Ecosystem (PACE) missions, was evaluated under diverse conditions, including flood and drought periods, Loop Current phase changes, and extreme weather events. A machine learning–based Gaussian Mixture Modeling (GMM) approach was also developed, providing a novel framework for dynamic front detection. By benchmarking traditional and machine learning methods, this integrated study identifies optimal algorithm–dataset combinations for resolving submesoscale and mesoscale features in the GoM, with applicability to other regions.

Pure And Strong Nash Equilibrium Computation In Compactly Representable Aggregate Games, Jared Soundy, Mohammad T. Irfan, Hau Chan

Research & Publications

Aggregate games model interdependent decision making when an agent’s utility depends on their own choice and the aggregation of everyone's choices. We define a compactly representable subclass of aggregate games we call additive aggregate games, which encompasses popular games like congestion games, anonymous games, Schelling games, etc. We study computational questions on pure Nash equilibrium (PNE) and pure strong Nash equilibrium (SNE). We show that PNE existence is NP-complete for very simple cases of additive aggregate games. We devise an efficient algorithmic scheme for deciding the existence of a PNE and computing one (if it exists) for bounded aggregate space. …

K-Mshc: Unmasking Minimally Sufficient Head Circuits In Large Language Models With Experiments On Syntactic Classification Tasks, Pratim Chowdhary, Peter Chin, Deepernab Chakrabarty

Computer Science Senior Theses

Understanding which neural components drive specific capabilities in mid-sized language models ($\leq$10B parameters) remains a key challenge. We introduce the $(\bm{K}, \epsilon)$-Minimum Sufficient Head Circuit ($K$-MSHC), a methodology to identify minimal sets of attention heads crucial for classification tasks as well as Search-K-MSHC, an efficient algorithm for discovering these circuits. Applying our Search-K-MSHC algorithm to Gemma-9B, we analyze three syntactic task families: grammar acceptability, arithmetic verification, and arithmetic word problems. Our findings reveal distinct task-specific head circuits, with grammar tasks predominantly utilizing early layers, word problems showing pronounced activity in both shallow and deep regions, and arithmetic verification demonstrating a …

Pure Nash Equilibrium And Strong Nash Equilibrium Computation In Additive Aggregate Games, Jared Soundy, Mohammad T. Irfan, Hau Chan

Research & Publications

Aggregate games, first conceptualized by Nobel laureate Reinhard Selten in 1970, model the decision-making of interdependent agents where each agent’s utility depends on their own action and the aggregation of everyone’s actions. We consider computational questions on pure Nash equilibrium (PNE) and pure strong Nash equilibrium (SNE) for aggregate games. On the way, we define a new subclass of aggregate games we call additive aggregate games, which encompasses popular games like congestion games, anonymous games, Schelling games, etc. We show that PNE existence is NPcomplete for very simple cases of additive aggregate games. We devise an efficient aggregate-space algorithm for …

Algorithms For Order Statistics In Farey Sequences: A Computational Study, Connor Weyers

School of Computing: Dissertations, Theses, and Student Research

Farey sequences are the sets of irreducible fractions in increasing order with denominator less or equal to some integer n. They are a well-known concept in number theory problems and are related to many other concepts in number theory including integer factoring, Fibonacci sequences, and Riemann’s Zeta function. In this paper, we investigate some known algorithms to solve certain problems in Farey sequences from a computational perspective. In particular, we implement established algorithms that have not been previously implemented with the goal of creating a package that can be used more broadly. We also develop a new algorithm for rational …

Review Of Algorithms Of Resistance: The Everyday Fight Against Platform Power, John G. Mcnutt

The Journal of Social Encounters

No abstract provided.

Precision Phenotyping For Curating Research Cohorts Of Patients With Unexplained Post-Acute Sequelae Of Covid-19, Alaleh Azhir, Jonas Hügel, Jiazi Tian, Jingya Cheng, Ingrid V Bassett, Douglas S Bell, Elmer V Bernstam, Maha R Farhat, Darren W Henderson, Emily S Lau, Michele Morris, Yevgeniy R Semenov, Virginia A Triant, Shyam Visweswaran, Zachary H Strasser, Jeffrey G Klann, Shawn N Murphy, Hossein Estiri

Faculty, Staff and Student Publications

BACKGROUND: Scalable identification of patients with post-acute sequelae of COVID-19 (PASC) is challenging due to a lack of reproducible precision phenotyping algorithms, which has led to suboptimal accuracy, demographic biases, and underestimation of the PASC.

METHODS: In a retrospective case-control study, we developed a precision phenotyping algorithm for identifying cohorts of patients with PASC. We used longitudinal electronic health records data from over 295,000 patients from 14 hospitals and 20 community health centers in Massachusetts. The algorithm employs an attention mechanism to simultaneously exclude sequelae that prior conditions can explain and include infection-associated chronic conditions. We performed independent chart reviews …

Abolition By Algorithm, Peter N. Salib

Michigan Law Review

In one sense, America’s newest abolitionist movement—advocating the elimination of policing and prison—has been a success. Following the 2020 Black Lives Matter protests, a small group of self-described radicals convinced a wide swath of ordinary liberals to accept a sweeping claim: Mere reforms cannot meaningfully reduce prison and policing’s serious harms. Only elimination can. On the other hand, abolitionists have failed to secure lasting policy change. The difficulty is crime. In 2021, following a nationwide uptick in homicides, liberal support for abolitionist proposals collapsed. Despite being newly “abolition curious,” left-leaning voters consistently rejected concrete abolitionist policies. Faced with the difficult …

Proxy Panels Enable Privacy-Aware Outsourcing Of Genotype Imputation, Degui Zhi, Xiaoqian Jiang, Arif Harmanci

Faculty, Staff and Student Publications

One of the major challenges in genomic data sharing is protecting participants' privacy in collaborative studies and in cases when genomic data are outsourced to perform analysis tasks, for example, genotype imputation services and federated collaborations genomic analysis. Although numerous cryptographic methods have been developed, these methods may not yet be practical for population-scale tasks in terms of computational requirements, rely on high-level expertise in security, and require each algorithm to be implemented from scratch. In this study, we focus on outsourcing of genotype imputation, a fundamental task that utilizes population-level reference panels, and develop protocols that rely on using …

A Review Of Artificial Intelligence, Algorithms, And Robots Through The Lens Of Stakeholder Theory, Michael J. Matthews, Su Runkun, Lindsey Yonish, Shawn Mcclean, Joel Koopman, Kai Chi Yam

Management Faculty Publications

With the arrival of the Fourth Industrial Revolution, intelligent machines are affecting the daily lives of multiple organizational stakeholders. However, despite the continued expansion of intelligent machines in society, management scholarship has generally lagged, and current frameworks are under-equipped to offer meaningful guidance regarding the intersection of intelligent machines and organizations. We address this issue via a multidisciplinary review and a novel framework of intelligent machines and value creation. First, we discuss the characteristics of intelligent machines (i.e., autonomy, learning, inscrutability, and materiality) and how variation in these characteristics impacts their affordances and, subsequently, the value offered to stakeholders. We …

Deep Learning-Based Auto-Segmentation For Liver Yttrium-90 Selective Internal Radiation Therapy, Jun Li, Wookjin Choi, Rani Anne

Department of Radiation Oncology Faculty Papers

The aim was to evaluate a deep learning-based auto-segmentation method for liver delineation in Y-90 selective internal radiation therapy (SIRT). A deep learning (DL)-based liver segmentation model using the U-Net3D architecture was built. Auto-segmentation of the liver was tested in CT images of SIRT patients. DL auto-segmented liver contours were evaluated against physician manually-delineated contours. Dice similarity coefficient (DSC) and mean distance to agreement (MDA) were calculated. The DL-model-generated contours were compared with the contours generated using an Atlas-based method. Ratio of volume (RV, the ratio of DL-model auto-segmented liver volume to manually-delineated liver volume), and ratio of activity (RA, …

Crisprofft: Comprehensive Database Of Crispr/Cas Off-Targets, Grant Wang, Xiaona Liu, Aoqi Wang, Jianguo Wen, Pora Kim, Qianqian Song, Xiaona Liu, Xiaobo Zhou

Faculty, Staff and Student Publications

The CRISPR (clustered regularly interspaced short palindromic repeats)/Cas (CRISPR-associated protein) programmable nuclease system continues to evolve, with in vivo therapeutic gene editing increasingly applied in clinical settings. However, off-target effects remain a significant challenge, hindering its broader clinical application. To enhance the development of gene-editing therapies and the accuracy of prediction algorithms, we developed CRISPRoffT (https://ccsm.uth.edu/CRISPRoffT/). Users can access a comprehensive repository of off-target regions predicted and validated by a diverse range of technologies across various cell lines, Cas enzyme variants, engineered sgRNAs (single guide RNAs) and CRISPR editing systems. CRISPRoffT integrates results of off-target analysis from 74 studies, encompassing …

Motion Artifacts Removal From Measured Arterial Pulse Signals At Rest: A Generalized Sdof-Model-Based Time-Frequency Method, Zhili Hao

Mechanical & Aerospace Engineering Faculty Publications

Motion artifacts (MA) are a key factor affecting the accuracy of a measured arterial pulse signal at rest. This paper presents a generalized time–frequency method for MA removal that is built upon a single-degree-of-freedom (SDOF) model of MA, where MA is manifested as time-varying system parameters (TVSPs) of the SDOF system for the tissue–contact-sensor (TCS) stack between an artery and a sensor. This model distinguishes the effects of MA and respiration on the instant parameters of harmonics in a measured pulse signal. Accordingly, a generalized SDOF-model-based time–frequency (SDOF-TF) method is developed to obtain the instant parameters of each harmonic in …

An Analytical Model Of Motion Artifacts In A Measured Arterial Pulse Signal—Part I: Accelerometers And Ppg Sensors, Md Mahfuzur Rahman, Subodh Toraskar, Mamun Hasan, Zhili Hao

Mechanical & Aerospace Engineering Faculty Publications

This paper, the first of two parts, presents an analytical model of motion artifacts (MAs) in measured pulse signals by accelerometers and photoplethysmography (PPG) sensors. As the transmission path from the true pulse signal in an artery to the sensor output (measured pulse signal), the tissue-contact-sensor (TCS) stack is modeled as a 1DOF (degree-of-freedom) system. MAs cause baseline drift of the mass and simultaneously time-varying system parameters (TVSPs) of the TCS stack. With arterial wall displacement and pulsatile pressure serving separately as the true pulse signal, an analytical model is developed to mathematically relate baseline drift and TVSP to a …

Motion Artifacts (Ma) At-Rest In Measured Arterial Pulse Signals: Time-Varying Amplitude In Each Harmonic And Non-Flat Harmonic-Ma Coupled Baseline, Md Mahfuzur Rahman, Mamun Hasan, Zhili Hao

Mechanical & Aerospace Engineering Faculty Publications

Motion artifacts (MA) cause great variability in a measured arterial pulse signal, and treatment of MA solely as a baseline drift (BD) fails to eliminate its effect on the measured signal. This paper presents a study on the effect of MA at rest (< 0.7 Hz) on measured arterial pulse signals using a microfluidic-based tactile sensor. By taking full account of the dynamic behavior of the transmission path from the true pulse signal in an artery to a measured pulse signal at the sensor, the tissue-contact-sensor (TCS) stack, an analytical model of MA in a measured pulse signal is developed. In this model, the TCS stack is treated as a 1DOF system for its dynamic behavior; MA is quantified as the displacement (i.e., BD) and time-varying system parameters (TVSP) of the TCS stack. The mathematical expression of MA in a measured pulse signal reveals that while BD remains as low-frequency additive noise, TVSP causes time-varying harmonics in a measured pulse signal. Further time-frequency analysis (TFA) of measured pulse signals validates the existence of TVSP and, for the first time, reveals its effect on a measured pulse signal: time-varying amplitude in each harmonic and non-flat harmonic-MA-coupled baseline.

Faithful Narratives From Complex Conceptual Models: Should Modelers Or Large Language Models Simplify Causal Maps, Tyler J. Gandee, Philippe J. Giabbanelli

VMASC Publications

(1) Background: Comprehensive conceptual models can result in complex artifacts, consisting of many concepts that interact through multiple mechanisms. This complexity can be acceptable and even expected when generating rich models, for instance to support ensuing analyses that find central concepts or decompose models into parts that can be managed by different actors. However, complexity can become a barrier when the conceptual model is used directly by individuals. A ‘transparent’ model can support learning among stakeholders (e.g., in group model building) and it can motivate the adoption of specific interventions (i.e., using a model as evidence base). Although advances in …

Time-Marching Quantum Algorithm For Simulation Of Nonlinear Lorenz Dynamics, Efstratios Koukoutsis, George Vahala, Min Soe, Kyriakos Hizanidis, Linda Vahala, Abhay K. Ram

Electrical & Computer Engineering Faculty Publications

Simulating nonlinear classical dynamics on a quantum computer is an inherently challenging task due to the linear operator formulation of quantum mechanics. In this work, we provide a systematic approach to alleviate this difficulty by developing an explicit quantum algorithm that implements the time evolution of a second-order time-discretized version of the Lorenz model. The Lorenz model is a celebrated system of nonlinear ordinary differential equations that has been extensively studied in the contexts of climate science, fluid dynamics, and chaos theory. Our algorithm possesses a recursive structure and requires only a linear number of copies of the initial state …

A Fast Framework For Generating Radioactive Mixture Spectra And Its Application To Remote High-Performance Mixture Identification, Chiman Kwan, Bulent Ayhan, Adam Stavola, Kazi Aminul Islam, Hongfang Zhang, Jiang Li

Electrical & Computer Engineering Faculty Publications

Remote detection of radioactive materials in mixtures using handheld or portal detectors remains a challenge because of factors such as low concentration, environmental interference, sensor noise, and other complications. This work introduces a fast framework for generating realistic mixture spectra. Moreover, we present mixture isotope identification using data generated by the fast framework. Researchers have examined a range of conventional and recent algorithms within the fields of machine learning and deep learning. An application to uranium enrichment-level prediction has been included. Extensive simulation experiments validated the efficacy of the proposed framework.

Differentiating Opioid Use Disorder From Healthy Controls Via Ml Analysis Of Rs-Fmri Networks, Ahmed Temtam, Megan A. Witherow, Liangsuo Ma, M. Shibly Sadique, F. Gerard Moeller, C. Kenneth, Dianne Wright, Khan M. Iftekharuddin

Electrical & Computer Engineering Faculty Publications

Objectives/Goals: This work aims to identify functional brain networks that differentiate opioid use disorder (OUD) subjects from healthy controls (HC) using machine learning (ML) analysis of resting-state fMRI (rs-fMRI). We investigate the default mode network (DMN), salience network (SN), and executive control network (ECN), as well as demographic features. Methods/Study Population: This work uses high-resolution rs-fMRI data from a National Institute on Drug Abuse study (IRB #HM20023630) with 31 OUD and 45 HC subjects. We extract rs-fMRI blood oxygenation level-dependent (BOLD) features from the DMN, SN, and ECN. The Boruta ML algorithm identifies statistically significant features and brain activity mapping …