Physical Sciences and Mathematics Commons^™

Novel Techniques For Enhancing Sensitivity In Static Headspace, Nicholas Snow, G.P Bullock

Nicholas A Snow

No abstract provided.

Simultaneous Determination Of Pramoxine Hcl And Benzalkonium Chloride In Wound Care Solutions By Hplc, Panagiotis Tavlarakis, Jonine Greyling, Nicholas Snow

Nicholas A Snow

No abstract provided.

Complementary Spectroscopic Assays For Investigating Protein−Ligand Binding Activity: A Project For The Advanced Chemistry Laboratory, David Mascotti, Mark Waner

Mark J. Waner

A protein−ligand binding, guided-inquiry laboratory project with potential application across the advanced undergraduate curriculum is described. At the heart of the project are fluorescence and spectrophotometric assays utilizing biotin-4-fluorescein and streptavidin. The use of the same stock solutions for an assay that may be examined by two distinct spectroscopic techniques offers an opportunity to discuss not only protein−ligand binding but also to compare instrumental techniques and to discuss the underlying physical principles that are the origins of the assays. In addition to critically evaluating analytical techniques, students are pushed to develop quantitative pipetting, estimation, and experimental-design skills to ...

The Social Implications Of Covert Policing, Simon Bronitt, Clive Harfield, K. Michael

Clive Harfield

Police agencies have been accused of suffering from an acute form of technophilia. Rather than representing some dreadful disorder, this assessment reflects the strong imperative, both in police agencies and the wider community, that police must have access to the latest technologies of surveillance and crime detection.

The last decade has witnessed the proliferation of low-cost surveillance technologies, some developed specifically for law enforcement purposes. Technology once the preserve of the military or secret intelligence agencies is now within the reach of ordinary general duties police officers. The new generation of police recruits is highly adept at using new technologies ...

An Interview With Mr Peter Mahy Of Howells Llp Who Represented S And Marper At The European Court Of Human Rights, Katina Michael, Peter Mahy

Associate Professor Katina Michael

Mr Peter Mahy, Partner at Howells LLP and the lawyer who represented S & Marper in front of the Grand Chamber at the European Court of Human Rights was interviewed by Katina Michael on the 10th of October 2009 while she was studying towards a Masters of Transnational Crime Prevention in the Faculty of Law at the University of Wollongong. In 2010 Peter Mahy received the Legal Aid Lawyer of the Year award for his contribution to the field. Mahy received his honours law degree from Sheffield University and a Masters in Criminology from the University of Cambridge. He did his ...

The European Court Of Human Rights Ruling Against The Policy Of Keeping Fingerprints And Dna Samples Of Criminal Suspects In Britain, Wales And Northern Ireland: The Case Of S. And Marper V United Kingdom, Katina Michael

Associate Professor Katina Michael

In England, Wales and Northern Ireland, the Police and Criminal Evidence Act 1984 (the PACE) contained powers for the taking of fingerprints, and samples in the form of deoxyribonucleic acid (DNA). In 2001, Section 64(1A) of the PACE was substituted with Section 82 of the Criminal Justice and Police Act. The change to legislation meant that a suspect of a crime would have their fingerprints and samples permanently stored on the police national computer (PNC) even after having been acquitted. This paper critically analyses the circumstances of the landmark case of S. AND MARPER V. THE UNITED KINGDOM in ...

Design And Synthesis Of Beta-Hairpin Peptidomimetics For Modulating Integrin Mediated Cell Adhesion, Abeta Fibrillogenesis And P53-Mdm2 Protein-Protein Interactions, Priyesh Jain

Graduate Theses and Dissertations

Inhibiting therapeutically important protein-protein interactions has been a tremendous challenge for medicinal chemists. The folded 3D structures of peptides and proteins, mainly comprise secondary structural elements i.e α-helices and β-sheet have created an opportunity to design small molecules and peptidomimetic inhibitors of protein-protein interaction (PPI). Hence, information about the formation and stabilization of these secondary structures is vital for designing future drugs. In this dissertation, several cyclic beta-hairpin peptidomimetics that mimic the recognition surface have been designed and synthesized as inhibitors for different targets such as integrin mediated extracellular matrix -cell adhesion in multiple myeloma, p53-MDM2 PPI, amyloid beta ...

Nevada Interagency Volunteer Program: Helping Hands Across Public Lands – Phase Ii: Quarterly Progress Report, Period Covering October 1, 2010 To December 31, 2010, Margaret N. Rees

Get Outdoors Nevada

• The number of records in the volunteer database decreased by 1.17% over the last quarter. The database now contains 6,534 records.
• Results show an average of 836 visits per month, with an average of 2,081 pages viewed per month.
• Get Outdoors Nevada supported nineteen volunteer events in a variety of ways. These events utilized 1,225 volunteers whom contributed 6,921 hours of service.
• Volunteer fall training has been completed with 61 volunteers attending 3 trainings.
• Fall training has been completed.
• Spring training scheduling is underway.
• Volunteer Orientation Training Automation is scheduled to be completed in February ...

Aspects Of The Life History Of The Snowy Grouper, Epinephelus Niveatus, In The Gulf Of Mexico, Kelley Kowal

Graduate Theses and Dissertations

Knowledge of many life history parameters are essential to properly assess and manage fish species. Although the snowy grouper, Epinephelus niveatus, is a commercially valuable fish, which is harvested throughout the Gulf of Mexico, little is known about its age, growth, and reproduction from this region. In this study, snowy grouper from the northern and eastern regions of the Gulf of Mexico were examined primarily using commercially-derived samples that were collected between 1984 and 2004. A total of 1,200 snowy grouper with fork lengths between 242 and 1,190 mm were collected. Sectioned saggital otoliths were used to determine ...

Lamprey Watershed Education And Outreach, Lamprey River Watershed Association, Dawn Genes, Lamprey River Watershed Association. Lamprey River Nominating Committee

PREP Reports & Publications

The Lamprey River Nomination Committee sought the assistance of the Piscataqua Region Estuaries Partnership (PREP) to complete an extensive and detailed information package to nominate the Lamprey River and its major tributaries to the NH Rivers Management and Protection Program. The nomination package was due at DES on June 1, 2010, was reviewed and accepted by the State Rivers Management Committee in September and forwarded to the Commissioner of DES. The nomination is now working through the NH legislature with hearings anticipated during the spring 2011 session. If passed, the bill should be signed by Governor Lynch in July of ...

Masthead

Journal of Digital Forensics, Security and Law

No abstract provided.

Front Matter

Journal of Digital Forensics, Security and Law

No abstract provided.

Revegetating Burned Arid Lands: Identifying Successful Native Species Using Trait And Competition Analysis: Final Report, Scott R. Abella

Fire Science

Species selection can make the difference between successful revegetation projects and costly failures. Candidate native species for revegetating burned arid lands in the southwestern United States must meet at least two criteria. These species must: (1) be competitive in postfire environments typically dominated by exotic grasses, and (2) be able to become established reliably by seeding or planting. In response to Manager’s Request Task 3 (reestablishment of native vegetation after fires on arid lands) in the 2006 JFS announcement for proposals, this research tackled the problem of selecting native species with the greatest chance of revegetation success by conducting ...

Lake Mead National Recreation Area Monitoring And Evaluation Of Sensitive Wildlife: Quarterly Progress Report, Period Ending December 31, 2010, Margaret N. Rees

Wildlife Monitoring

Project 1. Relict Leopard Frog Monitoring, Management, and Research

• Final milestones and deliverables for this project were completed this quarter.
• Fall monitoring surveys were completed at all sites.
• Habitat actions to improve breeding pools were conducted at one site.
• Data and associated metadata were compiled and quality assured.
• Final and annual reports were written and submitted in required formats for Clark County

and the Relict Leopard Frog Conservation Team.

Project 2. Bald Eagle Winter Monitoring and Evaluation

• This project was previously completed and all associated deliverables met.
• Efforts were provided this quarter in support of the 2011 winter count.

Project ...

Discovery Of Novel Viruses From Animals, Plants, And Insect Vectors Using Viral Metagenomics, Terry Fei Fan Ng

Graduate Theses and Dissertations

Understanding emerging viruses is critical for disease monitoring and prediction; however, surveys of novel viruses are hindered by the lack of a universal assay for viruses. Viral metagenomics, consisting of viral particle purification and shotgun sequencing, is a powerful technique for discovering viruses in a wide variety of sample types. However, current protocols are not effective on tissue samples (e.g., lungs, livers and tumors), where they are hindered by the high amount of host nucleic acids which limits the percentage of sequences that originate from viruses. In this dissertation, a modified viral metagenomics protocol was developed and utilized to ...

Corrole Synthesis And Catalytic Applications Toward Cobalt(Iii)-Catalyzed Epoxidation, N-H Insertion, And Cyclopropanation, Chung Sik Kim

Graduate Theses and Dissertations

A variety of bromocorroles, useful precusors for Pd-based cross coupling, were sucessfully synthesized in moderate to good yields. Chiral corroles were also synthesized through use of chiral amides in the aforementioned cross coupling reactions. Cobalt complexes bearing π-acceptor (CNtBu) and σ-donor (PPh3) ligands were also prepared in excellent yields. In this dissertation, cobalt (III) corrole complexes were applied to three different reaction areas: epoxidation, N-H insertion, and cyclopropanation. Cobalt(III) corroles were found to be efficient catalysts for epoxidation reactions. The epoxidation reactions can be carried out using ethyl phenyldiazoacetate, an acceptor/donor diazo compound, as a carbenoid precusor.The ...

Back Matter

Journal of Digital Forensics, Security and Law

No abstract provided.

Measurement Of Single- And Double-Spin Asymmetries In Deep Inelastic Pion Electroproduction With A Longitudinally Polarized Target, H. Avakian, Gerard P. Gilfoyle, Et. Al.

Physics Faculty Publications

We report the first measurement of the transverse momentum dependence of double-spin asymmetries in semi-inclusive production of pions in deep-inelastic scattering off the longitudinally polarized proton. Data have been obtained using a polarized electron beam of 5.7 GeV with the CLAS detector at the Jefferson Lab (JLab). Modulations of single spin asymmetries over the azimuthal angle between lepton scattering and hadron production planes φ have been measured over a wide kinematic range in Bjorken x and virtual photon squared four-momentum Q². A significant nonzero sin2φ single spin asymmetry was observed for the first time indicating strong spin-orbit ...

Urban And Rural-Residential Land Uses: Their Role In Watershed Health And The Rehabilitation Of Oregon’S Wild Salmonids, Michael Harte, Victor W. Kaczynski, Clinton C. Shock, J. Alan Yeakley, Robert M. Hughes, Nancy Molina, Carl B. Schreck

Environmental Science and Management Faculty Publications and Presentations

This technical report by the Independent Multidisciplinary Science Team (IMST) is a comprehensive review of how human activities in urban and rural-residential areas can alter aquatic ecosystems and resulting implications for salmonid recovery, with a geographic focus on the state of Oregon. The following topics are considered in the form of science questions, and comprise the major components of this report:

1. The effects of urban and rural-residential development on Oregon’s watersheds and native wild salmonids.
2. Actions that can be used to avoid or mitigate undesirable changes to aquatic ecosystems near developing urban and rural-residential areas.
3. The benefits and pitfalls ...

Dna Methylation And Its Association With Prenatal Exposures And Pregnancy Outcomes, Jennifer Straughen

Graduate Theses and Dissertations

Altered DNA methylation may lead to suboptimal fetal programming, increasing the risk of adverse pregnancy outcomes such as small for gestational age (SGA); however, few studies have examined the associations between DNA methylation, prenatal exposures, and fetal outcomes. Cross-sectional data from a larger, ongoing study were used to assess the impact of prenatal smoking on gene specific methylation of umbilical cord blood derived DNA and to investigate the association between gene-specific methylation and risk of SGA. The association between gene-specific DNA methylation and birthweight was also assessed. Maternal and infant covariates were abstracted from medical records, cigarette smoke exposure was ...

Evaluation Of Common Inherited Variants In Mitochondrial-Related And Microrna-Related Genes As Novel Risk Factors For Ovarian Cancer, Jennifer Permuth Wey

Graduate Theses and Dissertations

Epithelial ovarian cancer (EOC) is a leading cause of morbidity and mortality among women in the United States, and the etiology is incompletely understood. Common, low penetrant genetic variants such as single nucleotide polymorphisms (SNPs) likely contribute to a significant proportion of EOC. We examined whether SNPs in two understudied yet biologically important types of genes, mitochondrial-related and miRNA-related genes, may contribute to EOC susceptibility using data from a large, homogeneous study population of 1,815 EOC cases and 1,900 controls (frequency-matched on age-group and race/ethnicity) genotyped through stage 1 of an ongoing genome-wide association study. Inter-individual variation ...

A Framework For Determining The Reliability Of Nanoscale Metallic Oxide Semiconductor (Mos) Devices, Wilkistar Otieno

Graduate Theses and Dissertations

An increase in worldwide investments during the past several decades has pro-pelled scienti c breakthroughs in nanoscience and technology research to new and exciting levels. To ensure that these discoveries lead to commercially viable prod-ucts, it is important to address some of the fundamental engineering and scientific challenges related to nanodevices. Due to the centrality of reliability to product integrity, nanoreliability requires critical analysis and understanding to ensure long-term sustainability of nanodevices and systems. In this study, we construct a relia-bility framework for nanoscale dielectric lms used in Metallic Oxide Semiconductor (MOS) devices. The successful fabrication and incorporation of metallic ...

Near Minimum Energy Distributions On The Sphere Using Voronoi Cells, Benedictus Sitou Mensah

Masters Theses

No abstract provided.

Of Music, Mathematics, And Magic: Why Math Is All Made Up And Why It Works So Well, Gregory A. Leach

Masters Theses

No abstract provided.

The Social Implications Of Covert Policing, Simon Bronitt, Clive Harfield, K. Michael

Professor Katina Michael

Police agencies have been accused of suffering from an acute form of technophilia. Rather than representing some dreadful disorder, this assessment reflects the strong imperative, both in police agencies and the wider community, that police must have access to the latest technologies of surveillance and crime detection.

The last decade has witnessed the proliferation of low-cost surveillance technologies, some developed specifically for law enforcement purposes. Technology once the preserve of the military or secret intelligence agencies is now within the reach of ordinary general duties police officers. The new generation of police recruits is highly adept at using new technologies ...

Demonstrating The Potential For Covert Policing In The Community: Five Stakeholder Scenarios, Roba Abbas, Katina Michael, M.G. Michael

Professor Katina Michael

This paper presents the real possibility that commercial mobile tracking and monitoring solutions will become widely adopted for the practice of non traditional covert policing within a community setting, resulting in community members engaging in covert policing of family, friends, or acquaintances. This paper investigates five stakeholder relationships using scenarios to demonstrate the potential socio-ethical implications that tracking and monitoring people will have on society at large. The five stakeholder types explored in this paper include: (i) husband-wife (partner-partner), (ii) parent-child, (iii) employer-employee, (iv) friend-friend, and (v) stranger-stranger. Mobile technologies such as mobile camera phones, global positioning system data loggers ...

Global Patterns And Predictions Of Seafloor Biomass Using Random Forests, Chih-Lin Wei, Gilbert T. Rowe, Elva Escobar-Briones, Antje Boetius, Thomas Soltwedel, M. Julian Caley, Yousria Soliman, Falk Huettmann, Fangyuan Qu, Zishan Yu, C. Roland Pitcher, Richard L. Haedrich, Mary K. Wicksten, Michael A. Rex, Jeffrey G. Baguley, Jyotsna Sharma, Roberto Danovaro, Ian R. Macdonald, Clifton C. Nunnally, Jody W. Deming, Paul Montagna, Mélanie Lévesque, Jan Marcin Weslawski, Maria Wlodarska-Kowalczuk, Baban S. Ingole, Brian J. Bett, David S. M. Billett, Andrew Yool, Bodil A. Bluhm, Katrin Iken, Bhavani E. Narayanaswamy

Biology Faculty Publication Series

A comprehensive seafloor biomass and abundance database has been constructed from 24 oceanographic institutions worldwide within the Census of Marine Life (CoML) field projects. The machine-learning algorithm, Random Forests, was employed to model and predict seafloor standing stocks from surface primary production, water-column integrated and export particulate organic matter (POM), seafloor relief, and bottom water properties. The predictive models explain 63% to 88% of stock variance among the major size groups. Individual and composite maps of predicted global seafloor biomass and abundance are generated for bacteria, meiofauna, macrofauna, and megafauna (invertebrates and fishes). Patterns of benthic standing stocks were positive ...

Oracle And Multiple Robustness Properties Of Survey Calibration Estimator In Missing Response Problem, Kwun Chuen Gary Chan

UW Biostatistics Working Paper Series

In the presence of missing response, reweighting the complete case subsample by the inverse of nonmissing probability is both intuitive and easy to implement. However, inverse probability weighting is not efficient in general and is not robust against misspecification of the missing probability model. Calibration was developed by survey statisticians for improving efficiency of inverse probability weighting estimators when population totals of auxiliary variables are known and when inclusion probability is known by design. In missing data problem we can calibrate auxiliary variables in the complete case subsample to the full sample. However, the inclusion probability is unknown in general ...

Modification And Improvement Of Empirical Likelihood For Missing Response Problem, Kwun Chuen Gary Chan

UW Biostatistics Working Paper Series

An empirical likelihood (EL) estimator was proposed by Qin and Zhang (2007) for a missing response problem under a missing at random assumption. They showed by simulation studies that the finite sample performance of EL estimator is better than some existing estimators. However, the empirical likelihood estimator does not have a uniformly smaller asymptotic variance than other estimators in general. We consider several modifications to the empirical likelihood estimator and show that the proposed estimator dominates the empirical likelihood estimator and several other existing estimators in terms of asymptotic efficiencies. The proposed estimator also attains the minimum asymptotic variance among ...

Modification And Improvement Of Empirical Liklihood For Missing Response Problem, Gary Chan

UW Biostatistics Working Paper Series

An empirical likelihood (EL) estimator was proposed by Qin and Zhang (2007) for a missing response problem under a missing at random assumption. They showed by simulation studies that the finite sample performance of EL estimator is better than some existing estimators. However, the empirical likelihood estimator does not have a uniformly smaller asymptotic variance than other estimators in general. We consider several modifications to the empirical likelihood estimator and show that the proposed estimator dominates the empirical likelihood estimator and several other existing estimators in terms of asymptotic efficiencies. The proposed estimator also attains the minimum asymptotic variance among ...