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Articles 9211 - 9240 of 294493
Full-Text Articles in Physical Sciences and Mathematics
Effect Of Lithium Slag Dosage On Strength And Dry Shrinkage Properties Of Cement Stabilized Recycled Macadam, Zhao Ziyu, Gan Xianyong
Effect Of Lithium Slag Dosage On Strength And Dry Shrinkage Properties Of Cement Stabilized Recycled Macadam, Zhao Ziyu, Gan Xianyong
Journal of China & Foreign Highway
To improve the mechanical properties and dry shrinkage properties of cement stabilized bases formed by cold in-place recycling of cement concrete pavements,lithium slag was mixed into the recycled mixture in mass ratios of 0%,6%,9%,and 12%.The effects of lithium slag dosage on the mechanical,dry shrinkage,and water stability properties of the recycled base were analyzed through the unconfined compressive strength,splitting,dry shrinkage,and water stability tests,and the mechanism underlying the improving effect of lithium slag on the cement stabilized base formed by cold in-place recycling of the cement concrete pavement was analyzed by X-ray diffraction (XRD ) and scanning electron microscopy (SEM ).The results …
Mechanical Properties Of Transition Section Of Cable-Stayed Bridge With Kilometer-Scale Steel-Uhpc Composite Girders, Li Qiu, Zhi Haitao, Peng Yanqing, Peng Jianxin, Yuan Qin, Wu Xuewei
Mechanical Properties Of Transition Section Of Cable-Stayed Bridge With Kilometer-Scale Steel-Uhpc Composite Girders, Li Qiu, Zhi Haitao, Peng Yanqing, Peng Jianxin, Yuan Qin, Wu Xuewei
Journal of China & Foreign Highway
To study the mechanical properties of the steel-concrete composite section between steel box girders and steel-ultra-high performance concrete (UHPC ) composite girders,the Guanyinsi Yangtze River Bridge with a main span of 1 160 m was used as the background.Through refined finite element modeling,the stress characteristics under the most unfavorable load conditions and transmission mechanism of the steel-concrete composite section were analyzed,and the main factors affecting the stress of the composite section were discussed.The results indicate that under the most unfavorable load conditions,the stress of each component in the steel-concrete composite section is within 160.4 MPa,which is lower than the material …
Wind Tunnel Test Study On Wind-Resistant Performance Of Shuangliu Yangtze River Bridge, Li Xiukun, Wu Xuewei, Yang Can, Peng Xiaobin, Huang Zhiwen
Wind Tunnel Test Study On Wind-Resistant Performance Of Shuangliu Yangtze River Bridge, Li Xiukun, Wu Xuewei, Yang Can, Peng Xiaobin, Huang Zhiwen
Journal of China & Foreign Highway
The main bridge of Shuangliu Yangtze River Bridge on the Xingang Expressway in Wuhan City is a single-span suspension bridge with a main span of 1 430 m and a bridge tower of 272.75 m.The stiffening girder is in the form of a closed flat steel box girder with a width of 50.5 m.In order to study the wind-resistant performance of the bridge during operation,the performance of vortex-induced vibration of the girder was tested through wind tunnel tests of section model with two different geometric scales of 1∶60 and 1∶30,respectively.The sensitivity of the vortex-induced vibration response to the structural damping …
Comparison Of Calculation Methods For Local Scour In Bridge Pier Foundation Of Piles-Cushion Cap, Liu Hui, Jiang Yanhua, Yan Jiechao
Comparison Of Calculation Methods For Local Scour In Bridge Pier Foundation Of Piles-Cushion Cap, Liu Hui, Jiang Yanhua, Yan Jiechao
Journal of China & Foreign Highway
In order to analyze the calculation methods for local scour in bridge pier foundation of piles-cushion cap,this paper listed the six common Chinese and foreign calculation methods,described their calculation process and selection of calculation parameters,and analyzed the difference of the calculation methods according to typical engineering examples.The results show that there are differences in the selection of parameters in the calculation methods for local scour in bridge pier foundation of piles-cushion cap in Code for Survey and Design on Hydrology of Railway Engineering (TB 10017—2021 ) and Hydrological Specifications for Survey and Design of Highway Engineering (JTG C 30—2015 ),and …
Application Of Forward-Ba Ck Ana Lysis And Difference Iteration Method For Solving Initial Cable Tension Of Arch Bridge, Xu Yufeng, Li Zihui, Zhang Zhantao
Application Of Forward-Ba Ck Ana Lysis And Difference Iteration Method For Solving Initial Cable Tension Of Arch Bridge, Xu Yufeng, Li Zihui, Zhang Zhantao
Journal of China & Foreign Highway
This article presented a method that c ombined the forward-back analysis method and the difference iteration method to solve the initial cable tension according to the state of a built bridge for an arch bridge.Given the known target state of the bridge,a reasonable set of initial cable tensions was determined as the initial value of iteration by the forward-back method.These initial tensions were then applied to the calculation model based on the actual construction process.Through the difference iteration method,the initial cable tensions were optimized.The results show that the method can effectively determine the final cable tension that meets engineering precision …
Optimization Of Infill Concrete Dimension In Composite Girder Box Based On Igrnn, Wang Yafeng, Liu Jian, Ke Hongjun
Optimization Of Infill Concrete Dimension In Composite Girder Box Based On Igrnn, Wang Yafeng, Liu Jian, Ke Hongjun
Journal of China & Foreign Highway
The mechanical performance of the negative bending moment zone of steel-concrete composite continuous girders has always been a focus of attention in bridge engineering.Existing research mainly proposes improvement measures for the tension of concrete bridge decks,while paying little attention to the common phenomenon of steel girders bearing pressure.The steel girders in steel-concrete composite girders,especially the steel bottom plate in the negative bending moment area of the pier top,bear the highest compressive stress of the entire bridge.Therefore,by taking a steel-concrete composite girder bridge in Zhejiang Province as the engineering background,it is proposed to partially fill the interior of the box girder …
Experimental Study On Bending And Shear Performance Of Joint With Looped Reinforcement In Prefabricated Components, Liu Zhiquan, Hu Ke, Shi Xuefei, Zhong Yuzhuo
Experimental Study On Bending And Shear Performance Of Joint With Looped Reinforcement In Prefabricated Components, Liu Zhiquan, Hu Ke, Shi Xuefei, Zhong Yuzhuo
Journal of China & Foreign Highway
A joint with looped reinforcement is a type of steel bar connection structure with wet joints characterized by quick construction.In order to study the bending and shear stress performance and load-bearing capacity characteristics of the wet joints,four bearing capacity tests for bending and shear were designed and conducted for common application scenarios.The load,strain,and displacement changes of the specimens during the test process were tested,and the failure characteristics,load–displacement changes,and ultimate bearing capacity of this type of wet joint were analyzed.The results show that the wet joint with looped reinforcement has good ductility and conforms to the design principles of reinforced concrete.The …
Bending Moment Calculation And Reinforcement Recommendations For Cast-In-Place Cover Slabs In Slab Culverts, Li Yukun, Wan Kecheng, Fu Fulin
Bending Moment Calculation And Reinforcement Recommendations For Cast-In-Place Cover Slabs In Slab Culverts, Li Yukun, Wan Kecheng, Fu Fulin
Journal of China & Foreign Highway
To address the complexity and lack of practical methods for calculating bending moments of cast-in-place cover slabs in slab culverts,the slabs were simplified as one-way slabs with a pair of opposing edges simply supported and the other pair of edges free.Theoretical formulas for calculating the bending moments within the slabs under uniformly distributed loads were derived using elastic theory.The accuracy of the theoretical formulas was validated through case studies via finite element software.Various combinations of length,width,and fill heights exist in highway projects,making the use of theoretical formulas for bending moment calculations cumbersome.Therefore,a simplified method for calculating maximum bending moments in …
Research On Cable Force Optimization Of Long-Span Cable-Stayed Bridges Based On Rbfnn+Improved Parti Cle Swarm Optimization Algorithm, Deng Da, He Bowen, Liu Guokun
Research On Cable Force Optimization Of Long-Span Cable-Stayed Bridges Based On Rbfnn+Improved Parti Cle Swarm Optimization Algorithm, Deng Da, He Bowen, Liu Guokun
Journal of China & Foreign Highway
In view of the cable force optimization problem of long-span cable-stayed bridges,a cable force optimization method considering the reliability index of stay cables was proposed based on the response surface fitted by the radial basis function neural network (RBFNN ).The RBFNN-based response surface model for solving the reliability index was established by fitting the structural implicit function through RBFNN training.The improved particle swarm optimization algorithm was used to search for the optimal solution of the cable force optimization model considering the reliability index.The research results show that RBFNN can accurately predict the structural responses and fit the structural implicit performance …
Design Optimization And Experimental Study Of Cfrp Plate Anchorage With Clip-Extension Type, Qi Yijia, Xiao Dan, Wang Zhongqiang
Design Optimization And Experimental Study Of Cfrp Plate Anchorage With Clip-Extension Type, Qi Yijia, Xiao Dan, Wang Zhongqiang
Journal of China & Foreign Highway
Existing anchorage is prone to damaging the carbon-fiber reinforced polymer (CFRP ) plate due to the “notch effect ” and uneven distribution of clamping stress.This study proposed a new clip-extension type anchorage for the CFRP plate.This design utilized the ductility of steel for stress diffusion and guided the compressive stress zone in the CFRP plate away from the notched end,realizing a smooth transition of the clamping force of the CFRP plate at the clip port and effectively reducing the “notch effect ”.The design also reduced the strain difference between the carbon fibers,resulting in a more synchronized lateral deformation of the …
Research On Whole-Hole Testing Technology For Under-Anchor Tension In Prestressed Concrete Girders, Zhu Jianzhao, Dong Hao, Gu Jungang, Feng Lu, Li Shuyang, Zhang Shoulong, Chen Chaung
Research On Whole-Hole Testing Technology For Under-Anchor Tension In Prestressed Concrete Girders, Zhu Jianzhao, Dong Hao, Gu Jungang, Feng Lu, Li Shuyang, Zhang Shoulong, Chen Chaung
Journal of China & Foreign Highway
This study aims to propose a new testing method,namely whole-hole back-pull testing technology,to reduce costs and increase efficiency in under-anchor tension testing,effectively addressing the engineering challenges of large testing volume and tight schedules.Based on the principle of the traditional back-pull method,the mechanism of whole-hole back-pull testing technology was explained through theoretical analysis and formula derivation.Technical optimization was carried out in conjunction with experimental research,and a complete application method was proposed.A feasibility analysis was carried out.The study obtained the simplified mechanical model and typical test curves of the whole-hole back-pull testing technology and proposed a formula and application method for determining …
Research And Applicat Ion Of Ultra Large-Scale Consolidated Under-Reamed Drilled Shaft Technology Under Special Environmental And Geological Conditions, Ding Yi, Yu Kun, Shi Haiyang, Pei Xiaofeng, Zhu Bo
Research And Applicat Ion Of Ultra Large-Scale Consolidated Under-Reamed Drilled Shaft Technology Under Special Environmental And Geological Conditions, Ding Yi, Yu Kun, Shi Haiyang, Pei Xiaofeng, Zhu Bo
Journal of China & Foreign Highway
This article aims to add ress the poor economic efficiency of large-diameter and ultra-long piles,the high risk of hole collapse in thick sandy soil,and the limited space across the canal faced by the Bridge over Yellow River Diversion to Qindao Canal on Zhanhua ‒ Linyi Expressway.According to the comparison of conventional drilled cast-in-place piles with combined pile-end and pile-side post-grouting,the industry ’s under-reamed drilled shaft foundation with the largest disc diameter (4.5 m) and the largest single-pile volume (456 m3) was proposed and designed.At the same time,supporting devices such as three-arm rotary cutting drill bits and long arm borehole diameter …
Analysis Of Influence Of Internal Erosion On Deformation Of Subway Station Structure, Qin Tianxin, Wang Chen, Tan Xuyan, Wei Shengming, Liang Fayun
Analysis Of Influence Of Internal Erosion On Deformation Of Subway Station Structure, Qin Tianxin, Wang Chen, Tan Xuyan, Wei Shengming, Liang Fayun
Journal of China & Foreign Highway
Under the long-term effects of disasters such as rainstorms and floods,the soil layer around subway stations may be affected by internal erosion,threatening the structural safety of urban subway stations.To explore the influence of internal erosion on subway station structures,this study conducted isotropic consolidation and triaxial compression tests on gap-graded sand soil.Eroded soil specimens were simulated by adjusting the fine particle content to explore the pattern of variations in physical and mechanical properties caused by internal erosion.Results indicate that internal erosion alters the stress-strain relationship of gap-graded sand soil,increasing compressibility,decreasing shear strength,and weakening dilatancy.Drucker-Prager (DP) cap model parameters for eroded sand …
A Method For Determining Integrity Degree Of Tunnel Surrounding Rock Based On Mobilenet, Liu Houxiang, Yang Caixia
A Method For Determining Integrity Degree Of Tunnel Surrounding Rock Based On Mobilenet, Liu Houxiang, Yang Caixia
Journal of China & Foreign Highway
To determine the integrity degree of tunnel surrounding rock more efficiently,a precise determination method for the integrity degree of tunnel surrounding rock based on the lightweight neural network MobileNet-v 2 was proposed.Firstly,the image was grayscaled and denoised,and the edges of cracks were detected.Then,the lightweight neural network MobileNet-v 2 model was pre-trained on the ImageNet dataset,and combined with transfer learning to complete data detection on the training,validation,and testing sets.Finally,a comparative experiment was conducted with traditional neural networks RestNet- 50 and VGG 16.By identifying the area,width,and length of cracks,the crack ratio Ks was introduced as an indicator to evaluate the integrity of …
Settlement Mechanism And Re Inforcement Measure For Large-Diameter And Small-Clearance Parallel P Ipe Jacking Undercrossing Complex Building, Tang Gang, Huang Wen Jie, Zhang Wenbo, Li Wenjie, Liang Bin
Settlement Mechanism And Re Inforcement Measure For Large-Diameter And Small-Clearance Parallel P Ipe Jacking Undercrossing Complex Building, Tang Gang, Huang Wen Jie, Zhang Wenbo, Li Wenjie, Liang Bin
Journal of China & Foreign Highway
This study aims to study the settlem ent changes and distribution of various parts of a complex building during the construction of a large-diameter and small-clearance parallel pipe jacking undercrossing complex building.On the basis of the pipe jacking project of water quality guarantee engineering 2# for Tiegang –Shiyan Reservoir in Shenzhen,the settlement mechanism of pipe jacking undercrossing construction was analyzed.Through numerical simulation,the influence of the presence or absence of grouting reinforcement,and parameters such as longitudinal spacing and burial depth of pipe jacking on the variation trend and distribution law of building settlement was analyzed.The theoretically predicted values,numerical simulation values,and on-site …
Quantitative Evaluation Of Tunnel Rock Mass Integrity Based On Mwd Technology, Zhang Kunmu, Peng Hao, Liang Ming, Han Yu, Song Guanxian
Quantitative Evaluation Of Tunnel Rock Mass Integrity Based On Mwd Technology, Zhang Kunmu, Peng Hao, Liang Ming, Han Yu, Song Guanxian
Journal of China & Foreign Highway
In tunnel construction,the quantitative evaluation of rock mass integrity heavily relies on information from the exposed face,and there are challenges when drilling data is used for integrity evaluation.To this end,this study introduced a novel method for quantitative evaluation of rock mass integrity during drilling,integrating numerical statistics with machine learning.A substantial dataset of digital drilling data was collected,covering three common types of rock mass integrity:relatively intact,relatively fractured,and fractured.Subsequently,a high-performance random forest model for the classification of rock mass integrity was developed through data preprocessing and hyperparameter optimization.The interpretability of the model ’s predictive results was enhanced using Shapley additive explanations (SHAP …
Evaluation Method For Nighttime Visual Space Improvement On Mountain Roads, Zhao Yan, Chen Yanli, Chen Jiale
Evaluation Method For Nighttime Visual Space Improvement On Mountain Roads, Zhao Yan, Chen Yanli, Chen Jiale
Journal of China & Foreign Highway
To address issues such as poor visual guidance,narrow field of view,and short sight distance during nighttime driving on mountain roads,this study proposed a visual space enhancement evaluation method applicable to mountainous roads at night.By integrating active and passive traffic safety facilities,a visual space enhancement strategy adapted to the nighttime environment of mountain roads was proposed.A multidimensional evaluation indicator for visual space was established based on co-simulation.The effectiveness of the strategy was verified from the perspectives of visual space expansion and driving safety improvement by taking a trunk highway in the Qinling mountainous region as a case study.The results show that …
Object Detection And Tracking Based On Fusion Of Radar And Camera On Highway Side, Zeng Yongqiang, Zhang Yonghua, Zhao Hui, Liu Xin, Xu Mingsheng, Shen Jianwei, Hu Zhiwei, Chen Zhenquan
Object Detection And Tracking Based On Fusion Of Radar And Camera On Highway Side, Zeng Yongqiang, Zhang Yonghua, Zhao Hui, Liu Xin, Xu Mingsheng, Shen Jianwei, Hu Zhiwei, Chen Zhenquan
Journal of China & Foreign Highway
Camera is the most widely used sensor in intelligent transportation systems (ITS),but the decline of detection and positioning accuracy caused by target occlusion and external environment interference has always been an important factor restricting the development of ITS.In order to solve this problem,a multi-mode fusion target detection and tracking method based on millimeter-wave radar (MWR ) and camera on highway side was designed.Compared with cameras,high-resolution MWR had better measurement accuracy and weather robustness,serving as a better complement to camera perception.The proposed method used the center point-based radar and camera fusion algorithm for target detection and adopted the greedy algorithm for …
Construction And Application Of Knowledge Graph For Quality Management In Bridge Pile Engineering, Fang Xiaofeng, Dong Runhao, Gu Yanke, Pan Yanran
Construction And Application Of Knowledge Graph For Quality Management In Bridge Pile Engineering, Fang Xiaofeng, Dong Runhao, Gu Yanke, Pan Yanran
Journal of China & Foreign Highway
To enhance the efficiency of quality management in bridge pile foundation construction,this study constructed a knowledge graph applicable to the construction field of bridge pile foundation engineering to enable systematic representation and intelligent organization of knowledge.A methodology combining top-down design and bottom-up design was adopted to develop a framework for constructing a knowledge graph for the quality management of bridge pile foundation construction that encompasses both the schema layer and the data layer.The schema layer was established through ontology modeling,clarifying the concept categories,hierarchical structure,and their attribute relationships.The data layer employed a bidirectional long short-term memory (BiLSTM ) network integrated with …
Bending Capacity And Strengthening Design With Bonding Steel Plates Of Concrete Sections In French Standards, Wu Zi
Journal of China & Foreign Highway
In the French general technical clauses widely used in Francophone African countries,only the calculation principles for the bending capacity of normal concrete sections are provided,with explicit formulas not listed,and the strengthening design of structures is not involved.According to the fundamental principles of concrete structures and French standard regulations,the calculation formulas for the bending capacity of normal concrete sections were derived.On the basis of the assumptions of strengthening design,calculation formulas for strengthening with bonding steel plates were derived.Through practical engineering calculations conducted on the VDN Expressway project in Senegal,the applicability and reliability of the proposed formulas were verified.This study can offer …
Bridge Damage Detection And Bim Localization Methods Based On Image Recognition, Li Yu, Guo Hongjun
Bridge Damage Detection And Bim Localization Methods Based On Image Recognition, Li Yu, Guo Hongjun
Journal of China & Foreign Highway
To overcome insufficient information of 2D detection data in traditional bridge maintenance,which hinders precise decision-making,this study proposed an automated method based on deep learning and structure from motion (SfM ) technology,which realized the complete process from image recognition to the accurate mapping of damage information in a building information model (BIM ).First,the YOLOv 8 deep learning model was used to automatically detect bridge surface damage.Second,the SfM technology was applied for the local 3D reconstruction of the damage area and to determine the 3D coordinates of the damage.Then,the least squares method was used to align the local coordinate system with the …
Effects Of Π-Rich Solvents And Nickel And Cobalt Dopants On The Synthesis And Properties Of Cesium Lead Halide Nanocrystals, Tsung-Hsing Chiang
Effects Of Π-Rich Solvents And Nickel And Cobalt Dopants On The Synthesis And Properties Of Cesium Lead Halide Nanocrystals, Tsung-Hsing Chiang
Dissertations - ALL
Colloidal semiconductor nanocrystals feature unique properties like quantum confinement, tunable band gaps, and high surface-to-volume ratio; and have been proven as prominent materials in applications such as light-emitting diodes, sensors, lasers, solar cells, etc. Optoelectronic properties of semiconductor nanocrystals are highly associated with their sizes, morphologies, and compositions. Understanding the growth mechanism can lead to the ability to control the size, morphology, and composition of nanocrystals. In this thesis, growth and b-site doping of perovskite, cesium lead halide (CsPbX3), nanocrystals are discussed. Solvent effects in the growth of cesium lead bromide were first investigated from the aspect of plumbates in …
Robust Security Assurance In Cyber-Physical Systems: From Attack Diagnosis To Attack Resilience, Zifan Wang
Robust Security Assurance In Cyber-Physical Systems: From Attack Diagnosis To Attack Resilience, Zifan Wang
Dissertations - ALL
Cyber-Physical Systems (CPS) have become integral to critical infrastructure, from autonomous vehicles to industrial control systems. However, their increased connectivity and sophistication introduce new vulnerabilities, making security a paramount concern. This dissertation presents a comprehensive pipeline for enhancing CPS security, focusing on accurate diagnosis of trustworthy time frames and subsystems, followed by system resilience measures to restore safe states. The foundation of system resilience lies in an advanced checkpointing protocol for real-time multi-process systems. A novel three-step approach uniquely addresses both logical and timing correctness, which are crucial for modern CPS applications. By partitioning processes into directed acyclic graphs, implementing …
Model Inference And Sparse Network Analysis: Machine Learning In The Gene Regulatory Network Framework, Youchuan Wang
Model Inference And Sparse Network Analysis: Machine Learning In The Gene Regulatory Network Framework, Youchuan Wang
Dissertations - ALL
This thesis explores sparse network inference from high-dimensional, noisy, and underdetermined data—a fundamental challenge in many scientific domains. We focus on the development of evolutionary computation methods for discovering underlying network structures that are both interpretable and biologically plausible. Our methods are applied to the domain of Gene Regulatory Network (GRN) inference, where sparsity, indirect interactions, and limited observations pose significant hurdles. The framework models both steady-state and time-series gene expression data, with particular emphasis on biological sparsity and regulatory dynamics. We approach the problem from three perspectives: (1) edge-level analysis using transitive reduction to distinguish direct from indirect regulation; …
Enzyme Active Bath Affects Protein Condensation, Kevin Ching
Enzyme Active Bath Affects Protein Condensation, Kevin Ching
Dissertations - ALL
The idea that the activity of an active bath can act as an effective temperature and alter system behavior has been theorized and demonstrated for micron-scale systems, but it has not yet been shown for nanoscale systems. Previous studies have suggested that, although passive and active systems can be combined at the nanoscale, activity from the active system typically disrupts and destroys the passive system. In this work, I attempt to create an enzyme-driven active bath to control the liquid–liquid phase separation (LLPS) and condensation of a protein. I find that enzymatic activity enhances phase separation, effectively driving the LLPS …
Machine-Learning Classification Of Gamma-Producing Neutral Current Interactions In Liquid Argon From A Supernova Neutrino Burst, Sierra Thomas
Machine-Learning Classification Of Gamma-Producing Neutral Current Interactions In Liquid Argon From A Supernova Neutrino Burst, Sierra Thomas
Dissertations - ALL
With five core-collapse supernova candidates within 1 kiloparsec from Earth, extracting information from the neutrino flux will be important to understanding the explosion mechanism of the star (and its composition). The Deep Underground Neutrino Experiment, (DUNE), will be capable of detecting neutrinos from supernovae, primarily from charged-current interactions due to the electron neutrino flavor. However, considering neutrino oscillations in the presence of matter (MSW effects), the muon neutrinos and tau neutrinos will be undetectable if not for the neutral current channel. About 5% of the neutral current interactions will cause the argon nucleus to excite and release a gamma ray …
Developing Best Practice Fabrication For Niobium Superconducting Devices, Jadrien Timothy-Henke Paustian
Developing Best Practice Fabrication For Niobium Superconducting Devices, Jadrien Timothy-Henke Paustian
Dissertations - ALL
Superconducting qubits are a leading platform for scalable quantum computation. This platform offers high gate speeds and can make use of readily scalable complementary metal-oxide semiconductor (CMOS) fabrication techniques. However, superconducting qubits are susceptible to a variety of losses that arise in systems with superconductors, such as due to ubiquitous two-level systems, quasiparticles, and more. Designing fabrication processes to mitigate and manage these loss sources is critical to achieving scalable quantum computation. However, many of these loss sources are set during fabrication processing, of which there can be many different steps, each with its own parameter space. Exploring this space …
Balancing Robustness And Practicality In Model Compression, Personalization, And Healthcare Interventions, Sawinder Kaur
Balancing Robustness And Practicality In Model Compression, Personalization, And Healthcare Interventions, Sawinder Kaur
Dissertations - ALL
Advances in machine learning have enabled significant progress in generating robust solutions. However, designing solutions that balance robustness while meeting the practical constraints of diverse applications, such as limited resources and data, remains a challenge. We explored three key aspects of this interplay: verified robust compressed neural networks, context-wise robust personalization, and reliable counterfactual interventions for healthcare. First, we introduce VeriCompress, a novel framework to streamline the synthesis of compressed neural networks with formal guarantees of adversarial robustness. This enables the deployment of reliable and efficient models in resource-constrained environments, such as smartphones. Second, we developed CRoP (Context-wise Robust Static …
Exploring The Chemical And Biological Foundations Of Protein Lipidation Through Functional And Computational Studies, Andrea Sprague-Getsy
Exploring The Chemical And Biological Foundations Of Protein Lipidation Through Functional And Computational Studies, Andrea Sprague-Getsy
Dissertations - ALL
Post-translational modifications (PTMs) are essential for the diversification of the human proteome. Prenylation is a PTM defined by the addition of a 15-carbon or 20 carbon isoprenoid group by FTase and GGTase-I, respectively, onto a cysteine near the C-terminus of proteins. This modification is the first step within the prenylation pathway where proteolysis and carboxymethylation occur afterwards, aiding in proteins localization to the cellular membrane. These prenyltransferases canonically recognize a “CaaX” box motif which has been determined through biochemical and structural studies. Recently, sequences following the C(x)3X and Cxx patterns have been shown to be prenylated as well as an …
Adaptive Generation In Evolutionary Robotics: From Adversarial Objects To Guided Optimization, Unknown Akshay
Adaptive Generation In Evolutionary Robotics: From Adversarial Objects To Guided Optimization, Unknown Akshay
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Evolution-inspired algorithms have proven effective for complex optimization problems butsuffer from computational inefficiency due to their reliance on random variation operators. This is problematic in domains where fitness evaluation depends on expensive procedures such as training a neural network or running a robot, either in simulation or on hardware. This dissertation presents novel approaches for evolutionary robotics that replace stochastic evolutionary operations with learned, adaptive strategies using reinforcement learning (RL), significantly improving search efficiency while maintaining population diversity.The first contribution is a voxel-based evolutionary framework for generating adversarial objects that challenge robotic grasping systems. By evolving objects with controlled similarity …