Physical Sciences and Mathematics Commons^™

Radioluminescence Based Biochemical Sensing And Imaging Strategies To Measure Local Drug Release And Ph, Gretchen B. Schober

All Dissertations

In this dissertation we describe methods for measuring infection relevant biochemical analytes using radioluminescent and ultrasound luminescent materials. Films and nanoparticles fabricated with europium doped gadolinium oxysulfide (Gd₂O₂S:Eu³⁺) are used to quantitatively measure radiolabeled pharmaceutical concentration, specifically tritium labeled vancomycin (³H-vancomycin). Europium and dysprosium doped strontium aluminate is used to fabricate an ultrasound modulated, pH sensing film. These methods are indicated for theranostic evaluation of implant associated infection. Bacterial biofilms are inherently resistant to traditional antibiotic treatment and can coat biomedical implants. These biofilm related infections are difficult or impossible to eradicate …

Revealing The Role Of Electrostatics In Molecular Recognition, Ion Binding And Ph-Dependent Phenomena, Mihiri Hewa Bosthanthirige

All Dissertations

In this dissertation, we study the role of electrostatics in molecular recognition, ion binding and pH-dependent phenomena. In this work that includes three different research projects, the Poisson-Boltzmann (PB) model is used to describe the biological system and Delphi (which is a popular tool for solving the PB equation (PBE)) to study the electrostatics of biomolecular systems.

Chapter two aims to investigate the role of electrostatic forces in molecular recognition. We calculated electrostatic forces between binding partners separated at various distances. To accomplish this goal, we developed a method to find an appropriate direction to move one chain of protein …

Tempering The Adversary: An Exploration Into The Applications Of Game Theoretic Feature Selection And Regression, Stephen Mcgee

All Dissertations

Most modern machine learning algorithms tend to focus on an "average-case" approach, where every data point contributes the same amount of influence towards calculating the fit of a model. This "per-data point" error (or loss) is averaged together into an overall loss and typically minimized with an objective function. However, this can be insensitive to valuable outliers. Inspired by game theory, the goal of this work is to explore the utility of incorporating an optimally-playing adversary into feature selection and regression frameworks. The adversary assigns weights to the data elements so as to degrade the modeler's performance in an optimal …

Electrical And Optical Characterization Of Two-Dimensional Semiconductors Using Ultrafast Spectroscopy, Pan Adhikari

All Dissertations

The emergence of two-dimensional (2D) layered materials provides unprecedented opportunities for studying excitonic physics due to the strong Coulomb interaction between the electron-hole pair. Because of the reduced dimensionality and weak dielectric screening, the exciton is stable at room temperature, unlike bulk semiconductors. The evolution from low to high carrier density for optical gain in 2D semiconductors involves insulating exciton gas, exciton condensation, co-existence of various excitonic complexes, electron-hole plasmas (EHPs), or electron-hole liquids (EHLs), leading to the Mott transition. Strong interaction among the excitons, such as exciton-exciton annihilation (EEA), serves as a hot-carrier generation. A bound exciton dissociates into …

Controlled Manipulation Of Droplets On Fibers: Fundamentals And Printing Applications, Yueming Sun

All Dissertations

In this dissertation, the drop interactions with a single fiber is discussed under an application angle for the development on new Drop-on-Demand (DOD) printhead using a fiber-in-a-tube platform[1] to print highly viscous materials[2]. To control the drop formation and manipulation on fiber, one needs to know how the fiber wetting properties and the fiber diameter influence drop formation. And then, one needs to know the effects of fiber movement in the device on drop formation. These two questions constitute the main theme of this dissertation.

Before this study, it was accepted that the liquids could not form axisymmetric droplets if …

On Complete Integral Closure Of Integral Domains, Todd Fenstermacher

All Dissertations

Given an integral domain D with quotient field K, an element x in K is called integral over D if x is a root of a monic polynomial with coefficients in D. The notion of integrality has roots in Dedekind's work with algebraic integers, and was later developed more rigorously by Emmy Noether. Different variations or generalizations of integrality have since been studied, including almost integrality and pseudo-integrality. In this work we give a brief history of integrality and almost integrality before developing the basic theory of these two notions. We will continue the theory of almost integrality further by …

Data Augmentation Strategies For Eeg-Based Motor Imagery Decoding, Olawunmi George, Roger Smith, Praveen Madiraju, Nasim Yahyasoltani, Sheikh Iqbal Ahamed

Computer Science Faculty Research and Publications

The wide use of motor imagery as a paradigm for brain-computer interfacing (BCI) points to its characteristic ability to generate discriminatory signals for communication and control. In recent times, deep learning techniques have increasingly been explored, in motor imagery decoding. While deep learning techniques are promising, a major challenge limiting their wide adoption is the amount of data available for decoding. To combat this challenge, data augmentation can be performed, to enhance decoding performance. In this study, we performed data augmentation by synthesizing motor imagery (MI) electroencephalography (EEG) trials, following six approaches. Data generated using these methods were evaluated based …

Real-World Matching Performance Of Deidentified Record-Linking Tokens, Tian Liu, Alex Coda, Jonah Leshin

Faculty, Staff and Student Publications

OBJECTIVE: Our objective was to evaluate tokens commonly used by clinical research consortia to aggregate clinical data across institutions.

METHODS: This study compares tokens alone and token-based matching algorithms against manual annotation for 20,002 record pairs extracted from the University of Texas Houston's clinical data warehouse (CDW) in terms of entity resolution.

RESULTS: The highest precision achieved was 99.9% with a token derived from the first name, last name, gender, and date-of-birth. The highest recall achieved was 95.5% with an algorithm involving tokens that reflected combinations of first name, last name, gender, date-of-birth, and social security number.

DISCUSSION: To protect …

Building Consensus For A Shared Definition Of Adverse Events: A Case Study In The Profession Of Dentistry, Jini Etoule, Joel White, Ram Vaderhobli, Denice Stewart, Karla Kent, Alfa Yansane, Muhammad Walji

Faculty, Staff and Student Publications

BACKGROUND: To achieve high-quality health care, adverse events (AEs) must be proactively recognized and mitigated. However, there is often ambiguity in applying guidelines and definitions. We describe the iterative calibration process needed to achieve a shared definition of AEs in dentistry. Our alignment process includes both independent and consensus building approaches.

OBJECTIVE: We explore the process of defining dental AEs and the steps necessary to achieve alignment across different care providers.

METHODS: Teams from 4 dental institutions across the United States iteratively reviewed patient records after identification of charts using an automated trigger tool. Calibration across teams was supported through …

Development Of A Quality Improvement Dental Chart Review Training Program, Ana M Ibarra Noriega, Joel White, Muhammad F Walji

Faculty, Staff and Student Publications

INTRODUCTION: Chart review is central to understanding adverse events (AEs) in medicine. In this article, we describe the process and results of educating chart reviewers assigned to evaluate dental AEs.

METHODS: We developed a Web-based training program, "Dental Patient Safety Training," which uses both independent and consensus-based curricula, for identifying AEs recorded in electronic health records in the dental setting. Training included (1) didactic education, (2) skills training using videos and guided walkthroughs, (3) quizzes with feedback, and (4) hands-on learning exercises. In addition, novice reviewers were coached weekly during consensus review discussions. TeamExpert was composed of 2 experienced reviewers, …

Coastal Geomorphic Response To Sea-Level Rise, Storms, And Antecedent Geology: Examples From The Northern Gulf Of Mexico, Clayton Dike

Dissertations

Sea-level rise and tropical cyclone activity are threatening coastlines around the world. Past geologic coastal responses can be used to inform future scenarios. This three-part study examines the response of coastal systems to sea-level rise, storms, sediment supply, and antecedent geology over the past ~ 140 ka.

The first study is of the Bay St. Louis, Mississippi, coastal system along the northern Gulf of Mexico incorporating sediment supply, subsidence, and antecedent topography paired with an examination of geologic response to sea-level fall and rise. I used core and geophysical data that resolve incised valleys and other subsurface deposits from ~ …

Cobalt Telluride Electrocatalyst For Selective Electroreduction Of Co2 To Value-Added Chemicals, Apurv Saxena, Harish Singh, Manashi Nath

Chemistry Faculty Research & Creative Works

Recent emphasis on carbon dioxide utilization has necessitated the exploration of different catalyst compositions other than copper-based systems that can significantly improve the activity and selectivity towards specific CO₂ reduction products at low applied potential. In this study, a binary CoTe has been reported as an efficient electrocatalyst for CO₂ reduction in aqueous medium under ambient conditions at neutral pH. CoTe showed high Faradaic efficiency and selectivity of 86.83 and 75%, respectively, for acetic acid at very low potential of − 0.25 V vs RHE. More intriguingly, C1 products like formic acid was formed preferentially at slightly higher …

Faunal Comparison And Analysis Of The Blufftown Formation-Cusseta Sand Contact At Hannahatchee Creek, Georgia, Seth Fradella

Honors Theses

The origin of fossil material in the highly fossiliferous bed above the Upper Cretaceous (Campanian) Blufftown Formation-Cusseta Sand contact at Hannahatchee Creek, Georgia, has long been a subject of scientific curiosity; however, no research has yet been conducted to specifically investigate discrepancies between the fossil assemblages of the upper Blufftown Formation and the basal Cusseta Sand, which overlies it unconformably. In the most recent published hypothesis, Case and Schwimmer (1988) propose that the basal Cusseta Sand contains a mixture of original fauna as well as material reworked and redeposited from the underlying Blufftown Formation, resulting in a lag deposit above …

Defining The Current Distribution Of The Imperiled Black-Spotted Newt Across South Texas, Usa, Padraic S. Robinson, Drew R. Davis, Sean M. Collins, Richard Kline

School of Earth, Environmental, & Marine Sciences Faculty Publications

The Black-spotted Newt (Notophthalmus meridionalis) is a chronically understudied salamander species, with many aspects of its natural history, ecology, and distribution poorly known. Previous studies using traditional methodologies have had limited success documenting N. meridionalis on the landscape, detecting individuals at 6% (7 of 114) and 1% (2 of 221) of sites surveyed. A novel environmental DNA (eDNA) assay was designed and implemented with the goals of assessing the current distribution of N. meridionalis across south Texas, USA, and better understanding the conditions for positive eDNA detections. We conducted eDNA sampling and traditional surveys at 80 sites throughout …

The Ukicer 2022 Conference Poster: Techmate: A Best Practice Toolkit For Driving Sustainable Acceleration Towards Gender Equality In Technology Disciplines In Heis., Alina Berry

Conference papers

TechMate is a research project that is being developed to enhance gender balance in technology disciplines, in particular computing higher education in Ireland and beyond. Gender imbalance in computing education is a well-known issue: in Ireland, less than 15% of the student population in computer science, ICT and related disciplines are women. Despite a significant amount of research and practical work conducted in the recent decades, the problem still persists and this research initiative aims to improve the situation.

Among the main aims of this project, there is a development of a toolkit to drive sustainable acceleration towards gender equality …

An Investigation Of The Yidc-Mediated Membrane Insertion Of Pf3 Coat Protein Using Molecular Dynamics Simulations, Adithya Polasa, Jeevapani Hettige, Kalyan Immadisetty, Mahmoud Moradi

Chemistry & Biochemistry Faculty Publications and Presentations

YidC is a membrane protein that facilitates the insertion of newly synthesized proteins into lipid membranes. Through YidC, proteins are inserted into the lipid bilayer via the SecYEG-dependent complex. Additionally, YidC functions as a chaperone in protein folding processes. Several studies have provided evidence of its independent insertion mechanism. However, the mechanistic details of the YidC SecY-independent protein insertion mechanism remain elusive at the molecular level. This study elucidates the insertion mechanism of YidC at an atomic level through a combination of equilibrium and non-equilibrium molecular dynamics (MD) simulations. Different docking models of YidC-Pf3 in the lipid bilayer were built …

Inducing Spin-Order With An Impurity: Phase Diagram Of The Magnetic Bose Polaron, Simeon I. Mistakidis, G. M. Koutentakis, F. Grusdt, P. Schmelcher, H. R. Sadeghpour

Physics Faculty Research & Creative Works

We Investigate The Formation Of Magnetic Bose Polaron, An Impurity Atom Dressed By Spin-Wave Excitations, In A One-Dimensional Spinor Bose Gas. Within An Effective Potential Model, The Impurity Is Strongly Confined By The Host Excitations Which Can Even Overcome The Impurity-Medium Repulsion Leading To A Self-Localized Quasi-Particle State. The Phase Diagram Of The Attractive And Self-Bound Repulsive Magnetic Polaron, Repulsive Non-Magnetic (Fröhlich-Type) Polaron And Impurity-Medium Phase-Separation Regimes Is Explored With Respect To The Rabi-Coupling Between The Spin Components, Spin-Spin Interactions And Impurity-Medium Coupling. The Residue Of Such Magnetic Polarons Decreases Substantially In Both Strong Attractive And Repulsive Branches With Strong …

Study Of The Very High Energy Emission Of M87 Through Its Broadband Spectral Energy Distribution, R. Alfaro, C. Alvarez, J. C. Arteaga-Velázquez, D. Avila Rojas, H. A. Ayala Solares, E. Belmont-Moreno, T. Capistrán, A. Carramiñana, S. Casanova, U. Cotti, J. Cotzomi, S. Coutiño De León, E. De La Fuente, C. De León, R. Diaz Hernandez, M. A. Duvernois, M. Durocher, J. C. Díaz-Vélez, C. Espinoza, K. L. Fan, M. Fernandez Alonso, N. Fraija, J. A. Garcia-Gonzalez, F. Garfias, M. M. Gonzalez, J. A. Goodman, J. P. Harding, G. Huang, F. Hueyotl-Zahuantitla, P. Huntemeyer, V. Joshi, H. Leon Vargas, J. T. Linnemann, A. L. Longinotti, G. Luis-Raya, K. Malone, O. Martinez, J. Martinez-Castro, J. A. Matthews, P. Miranda-Romagnoli, E. Moreno, M. Mostafa, A. Nayerhoda, L. Nellen, R. Noriega-Papaqui, N. Omodei, A. Peisker, E. G. Perez-Perez, C. D. Rho, D. Rosa-Gonzalez, H. Salazar, D. Salazar-Gallegos, F. Salesa Greus, A. Sandoval, J. Serna-Franco, Y. Son, R. W. Springer, O. Tibolla, K. Tollefson, I. Torres, F- Urena-Mena, L. Villasenor, Xiaojie Wang, E. Willox, A. Zepeda

Physics Faculty Research & Creative Works

The radio galaxy M87 is the central dominant galaxy of the Virgo Cluster. Very high-energy (VHE, ≳0.1 TeV) emission from M87 has been detected by imaging air Cherenkov telescopes. Recently, marginal evidence for VHE long-term emission has also been observed by the High-Altitude Water Cherenkov Observatory, a gamma-ray and cosmic-ray detector array located in Puebla, Mexico. The mechanism that produces VHE emission in M87 remains unclear. This emission originates in its prominent jet, which has been spatially resolved from radio to X-rays. In this paper, we construct a spectral energy distribution from radio to gamma rays that is representative of …

C -Axis Transport In Ute2: Evidence Of Three-Dimensional Conductivity Component, Yun Suk Eo, Shouzheng Liu, Shanta R. Saha, Hyunsoo Kim, Sheng Ran, Jarryd A. Horn, Halyna Hodovanets, John Collini, Tristin Metz, Wesley T. Fuhrman, Andriy H. Nevidomskyy, Jonathan D. Denlinger, Nicholas P. Butch, Michael S. Fuhrer

Physics Faculty Research & Creative Works

We study the temperature dependence of electrical resistivity for currents directed along all crystallographic axes of the spin-triplet superconductor UTe2. We focus particularly on an accurate determination of the resistivity along the c axis (ρc) by using a generalized Montgomery technique that allows extraction of crystallographic resistivity components from a single sample. In contrast to expectations from the observed highly anisotropic band structure, our measurement of the absolute values of resistivities in all current directions reveals a surprisingly nearly isotropic transport behavior at temperatures above Kondo coherence, with ρc∼ρb∼2ρa, that evolves to reveal qualitatively distinct behaviors on cooling. The temperature …

Two-Path Interference In Resonance-Enhanced Few-Photon Ionization Of Li Atoms, B. P. Acharya, S. Dubey, K. L. Romans, A. H.N.C. De Silva, K. Foster, O. Russ, K. Bartschat, N. Douguet, Daniel Fischer

Physics Faculty Research & Creative Works

We investigate the resonance-enhanced few-photon ionization of atomic lithium by linearly polarized light whose frequency is tuned near the 2s-2p transition. Considering the direction of light polarization orthogonal to the quantization axis, the process can be viewed as an atomic "double-slit experiment "where the 2p states with magnetic quantum numbers mℓ=±1 act as the slits. In our experiment, we can virtually close one of the two slits by preparing lithium in one of the two circularly polarized 2p states before subjecting it to the ionizing radiation. This allows us to extract the interference term between the two pathways and obtain …

Self-Intercalation Tunable Interlayer Exchange Coupling In A Synthetic Van Der Waals Antiferromagnet, Xiaoqian Zhang, Wenqing Liu, Wei Niu, Qiangsheng Lu, Wei Wang, Ali Sarikhani, Xiaohua Wu, Chunhui Zhu, Jiabao Sun, Mitchel Vaninger, Paul F. Miceli, Jianqi Li, David J. Singh, Yew San Hor

Physics Faculty Research & Creative Works

One of the most promising avenues in 2D materials research is the synthesis of antiferromagnets employing 2D van der Waals (vdW) magnets. However, it has proven challenging, due in part to the complicated fabrication process and undesired adsorbates as well as the significantly deteriorated ferromagnetism at atomic layers. Here, the engineering of the antiferromagnetic (AFM) interlayer exchange coupling between atomically thin yet ferromagnetic CrTe2 layers in an ultra-high vacuum-free 2D magnetic crystal, Cr5Te8 is reported. By self-introducing interstitial Cr atoms in the vdW gaps, the emergent AFM ordering and the resultant giant magnetoresistance effect are induced. A large negative magnetoresistance …

Final Butte Reclaimed Areas Maintenance And Monitoring (M&M) Plan In Accordance With Butte Reclamation Evaluation System (Bres), Pioneer Technical Services, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

A Climate Resilience Research Renewal Agenda: Learning Lessons From The Covid-19 Pandemic For Urban Climate Resilience, Mark Pelling, Winston T. L. Chow, Eric Chu, Richard Dawson, David Dodman, Arabella Fraser, Bronwyn Hayward, Luna Khirfan, Timon Mcphearson, Anjal Prakash, Gina Ziervogel

Research Collection School of Social Sciences

Learning lessons from the COVID-19 pandemic opens an opportunity for enhanced research and action on inclusive urban resilience to climate change. Lessons and their implications are used to describe a climate resilience research renewal agenda. Three key lessons are identified. The first lesson is generic, that climate change risk coexists and interacts with other risks through overlapping social processes, conditions and decision-making contexts. Two further lessons are urban specific: that networks of connectivity bring risk as well as resilience and that overcrowding is a key indicator of the multiple determinants of vulnerability to both COVID-19 and climate change impacts. From …

Quantification Of Hydrologic Response To Forest Disturbance In Western U.S. Watersheds, Sara A. Goeking

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Forested watersheds produce more than half of the water supply in the United States. Forests affect how precipitation is partitioned into available water versus evapotranspiration. This dissertation investigated how water yield and snowpack responded to forest disturbance following recent disturbances in western U.S. forests during the period 2000-2019.

Chapter 2 systematically reviewed 78 recent studies that examined how water yield or snowpack changed after forest disturbances. Water yield and snowpack often increased after disturbance, but decreased in some circumstances. Decreased water yield was most likely to occur following disturbances that did not remove the entire forest canopy. It was also …

Developing Confidence And Interest In Teaching Relevant Mathematical Modeling Lessons, Jacy Beck

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

What is mathematical modeling and how can inservice and pre-service teachers develop the skills and competencies necessary to increase confidence and interest in teaching relevant mathematical modeling lessons? Mathematical modeling is “the process of choosing and using appropriate mathematics and statistics to analyze empirical situations, to understand them better, and to improve decisions” (CSSM, 2010, p. 72). By providing students with an opportunity to engage in relevant mathematical modeling prompts, we provide them with transferable skills and knowledge. The aim of this paper will be to provide insight into the relevance of teaching mathematical modeling, provide resources for integrating modeling …

Urban Soil Chemical And Nutrient Management Issues Facing Emerging Small Grower Enterprises In Utah, Frank E. Oliver

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Knowledge of both soil quality and contamination has become increasingly important with the growth of urban agriculture in Utah and the United States as whole. Land is also a common limiting factor in urban agriculture, so it is important to maximize yield and net returns. In order to meet these demands, three studies were conducted across key urban agriculture sites along the Wasatch Front: 1) an urban soil survey to assess soil contamination, 2) an urban soil survey to evaluate macronutrient and salinity levels, and 3) a nitrogen fertilizer management trial for dahlia (Dahlia pinnata), a cut flower …

Defining Areas Of Interest Using Voronoi And Modified Voronoi Tesselations To Analyze Eye-Tracking Data, Joanna D. Coltrin

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Eye tracking is a technology used to track where someone is looking. Eye-tracking technology is often used to study what people focus on when looking at a photo of another person. The eye-tracking technology records points on a photo that a person is looking at. When the photo being looked at shows a person, the points can be categorized by body part such as head, right hand, left hand, and torso. This thesis presents the use of partially circular areas to define the body parts of the person in the photo and therefore categorize the points collected by the eye-tracker. …

Evaluation Of The Geothermal Potential Of The Camas Prairie, South-Central Idaho, Connor J. Smith

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The area studied in this thesis was assessed based on the analysis of a water sample collected from the exploratory well USU Camas-1. The water sample was characterized and compared to other water samples collected and analyzed during a previous phase of this project according to its water chemistry.

Lithologic, geophysical, and temperature logs were also used to assess the study area. The depth sensitive data was analyzed to determine the characteristics of the formation as they relate to the favorable parameters of a geothermal resource, those being permeability of the subsurface, heat, and the presence of a clay seal. …

Conservation Conflict: Rare Plant Conservation And Energy Development And Potential In The Colorado Plateau, Joshua Carrell

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The Colorado Plateau provides numerous sources of energy, particularly natural oil and gas. This energy potential is being actively extracted for consumption on both public and private lands. Elements of biodiversity (e.g., listed and sensitive plant and animal species) are distributed among all land tenures, yet the laws protecting them can vary depending if they occur on public, private, or tribal land. Therefore, it is necessary to understand the geographic ranges of threatened, endangered, and sensitive species and their relationship to land ownership to preserve habitat and conserve species populations. I developed species distribution models (SDMs) to examine the predicted …

Investigating Factors That Impact Income Generation And Distribution In Western National Park Gateway Communities, Elizabeth Depew

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Many rural towns in the western united states have come to be defined by high levels of tourism, seasonal residents, and migration driven by the desire to be close to natural amenities and the higher quality of life they afford. This shift is especially apparent in communities that are “gateways” to natural amenities such as national parks. Embracing this shift towards the “New West,” many community planners have heralded amenity-led development as a remedy to the waning feasibility of relying on agriculture and extractive industries. However, anecdotal evidence and several case studies indicate the factors which make these gateway communities …