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Articles 4441 - 4470 of 294607
Full-Text Articles in Physical Sciences and Mathematics
Detecting Sophisticated Cyberattacks On Public Water Infrastructure, Ayrton Purdy
Detecting Sophisticated Cyberattacks On Public Water Infrastructure, Ayrton Purdy
Graduate Theses and Dissertations (2019 - present)
In recent years there has been an increasing number of cyberattacks on public water generation and distribution systems. Advanced persistent attackers could usurp sensors and control systems to contaminate public drinking water. In order to conceal their malicious activity, they can manipulate sensor data flows to give the appearance of normal activity. The compromised sensors would report normal chemical levels even though unsafe water is entering the distribution system. In response, this research proposes a multi-sensor, cross-comparison approach to anomaly detection. The proposed approach is designed to detect sophisticated cyberattacks which are not easily detectable using traditional cyber tools. The …
Developing A Framework For Microchip Design Recovery, Eric Diep
Developing A Framework For Microchip Design Recovery, Eric Diep
Graduate Theses and Dissertations (2019 - present)
Due to the increase in diverse chip production over the past decade, reverse engineering has become a difficult and daunting task. This research develops a methodology for microchip design recovery, seeking to validate and reproduce prior approaches to physical reverse engineering using low-cost tools and techniques. We used mechanical hardware abrasion tools and techniques to delayer and capture silicon integrated chip (IC) layout. We focused on the Mifare Classic EVl microchip, commonly implemented in public transit/transportation cards, to extract information for design recovery. The research explores limitations and advantages of mechanical abrasion and optical microscopy in context to modem chip …
Passive Microwave Remote Sensing Of Flash Drought Impacts On Vegetation, Quinton R. Deppert
Passive Microwave Remote Sensing Of Flash Drought Impacts On Vegetation, Quinton R. Deppert
School of Natural Resources: Dissertations, Theses, and Student Research
In 2002, Dr. Mark Svoboda characterized a new form of drought known as flash drought. Flash drought was defined as a rapid decline in vegetation health caused by severe heat and drought. In recent years, attempts to quantify the impacts of flash drought via precipitation, soil moisture, evapotranspiration, and temperature indicators have proliferated. What has rarely been quantified is what the rapid decline in vegetation health amid flash drought looks like through remote sensing. This is because vegetation health indices like the Normalized Difference Vegetation Index (NDVI) are derived from the visible and infrared regions of the electromagnetic spectrum and …
Hollow Nickel-Iron Nanoshells As Electrocatalysts For The Oxygen Evolution Reaction, Jonathan Batey
Hollow Nickel-Iron Nanoshells As Electrocatalysts For The Oxygen Evolution Reaction, Jonathan Batey
Chemistry & Biochemistry Undergraduate Honors Theses
The development of highly active and affordable catalysts for the oxygen evolution reaction is crucial to achieve a future where hydrogen is generated cleanly using renewable methods. Ni-Fe nanocatalysts show great promise in this area, as they are affordable and highly active. However, to overcome the industrial dominance of steam methane reforming, their activity needs improvement. This work aims to increase the activity of Ni-Fe nanocatalysts by making hollow nanostructures. Hollow Ni-Fe nanostructures were synthesized by coating a Cu template with Ni and Fe, followed by the etching of the Cu template. This left hollow Ni-Fe nanoshells, which were used …
Sumset Lower Bounds In Abelian Groups, Van T. Huynh
Sumset Lower Bounds In Abelian Groups, Van T. Huynh
Honors Theses
This thesis investigates sumset lower bounds across discrete and continuous settings. We begin with general inequalities in torsion-free abelian groups and then specialize to the integers modulo prime p, where we present the Cauchy–Davenport Theorem, which establishes the bound ∣A+B∣≥min(p,∣A∣+∣B∣−1). The equality case is further examined via Vosper's Theorem, which characterizes subsets attaining this bound as arithmetic progressions under suitable conditions. The continuous analogue in Euclidean spaces is then considered, where cardinality is replaced by Lebesgue measure. In this setting, the Brunn–Minkowski Inequality provides a sharp lower bound for the Lebesgue measure of A+B and serves as a geometric counterpart …
Provenance Analysis Of Advanced Persistent Threats In Operational Technology Environments, Laura Aminta Guevara
Provenance Analysis Of Advanced Persistent Threats In Operational Technology Environments, Laura Aminta Guevara
Open Access Theses & Dissertations
Live vulnerability testing and penetration assessments of critical infrastructure are costly, complex operationally and, in many cases, unsafe to conduct directly against live systems, whether these are commissioned in-house and through third-party providers. For Operational Technology environments specifically, these constraints are further aggravated by the limited vendor support and inconsistent security patching available that characterize many industrial communication protocols. This significantly restricts the scope and feasibility of conventional penetration testing. At the same time, the increasing overlapping of OT systems with enterprise networks and the internet has expanded the attack surface of ICS infrastructure, making more pressing the need for …
Numerical Methods For Modeling Darcy-Forchheimer Flow In Heterogeneous Porous Media, Nate Mcnair
Numerical Methods For Modeling Darcy-Forchheimer Flow In Heterogeneous Porous Media, Nate Mcnair
Open Access Theses & Dissertations
Classic approaches to modeling fluid flow in porous media rely on Darcy's Law, which assumes a linear relationship between volumetric flow rate and the pressure gradient. However, in recent years, applications such as enhanced geothermal systems have highlighted the need to model nonlinear flow behavior, since experimental and observational data show that, once flow velocity exceeds a certain threshold, the relationship between velocity and macroscopic pressure gradient becomes nonlinear. This requires alternative models that more accurately capture the physical behavior of these systems.The Darcy-Forchheimer model provides one such alternative by introducing a nonlinear velocity-pressure relationship. However, this nonlinearity creates additional …
Log Anomaly Detection With Parameter-Efficient Tiny Language Models: From Centralized Fine-Tuning To Privacy-Preserving Federated Learning, Isaiah Thompson Thompson Ocansey
Log Anomaly Detection With Parameter-Efficient Tiny Language Models: From Centralized Fine-Tuning To Privacy-Preserving Federated Learning, Isaiah Thompson Thompson Ocansey
Open Access Theses & Dissertations
System logs are a primary source of information for identifying faults, misconfigurations, and security incidents in computing infrastructure. As these logs grow in volume and complexity, manual inspection becomes impractical, and automated detection methods are needed. This thesis investigates how compact language models can be applied to the task of log anomaly detection under two operational conditions: when log data is centralized and when it is located at different data sites.
In the first part, we propose LogTinyLLM, which applies parameter-efficient fine-tuning through Low-Rank Adaptation and adapter-based techniques to adapt tiny language models for identifying contextual anomalies in log sequences. …
An Ordinal Categorical Data Analysis Using The Stereotype Model Within A Bayesian Framework With A Logistic-Normal Prior, Nathaniel A. Sakyi
An Ordinal Categorical Data Analysis Using The Stereotype Model Within A Bayesian Framework With A Logistic-Normal Prior, Nathaniel A. Sakyi
Open Access Theses & Dissertations
Ordinal categorical data are pervasive in applied research, yet their analysis is often compromised by modeling strategies that implicitly assume equidistant category spacing or impose restrictive structural constraints. Metric regression models and latent-variable threshold approaches routinely misrepresent ordinal information, leading to biased inference, distorted uncertainty quantification, and loss of structural insight. This paper develops a Bayesian framework for ordinal regression that explicitly accommodates \textbf{unequal spacing among ordered response categories} while preserving ordinal structure and interpretability.
The proposed approach builds on the stereotype regression model, which embeds ordinal categories into a latent one-dimensional continuum through estimable score parameters. While the stereotype …
Hvsr-Based Resonance Analysis And Fault Zone Characterization In The El Paso Region, Alexandro Dominguez
Hvsr-Based Resonance Analysis And Fault Zone Characterization In The El Paso Region, Alexandro Dominguez
Open Access Theses & Dissertations
Horizontal to Vertical Spectral Ratio (HVSR) analysis offers an efficient method for characterizing near-surface structure, resolving sediment thickness, and identifying fault-controlled basin geometry in regions with strong impedance contrasts. This study applies HVSR techniques to continuous ambient-noise recordings collected across the El Paso region, a tectonically active segment of the southern Rio Grande Rift where accurate subsurface mapping is essential for seismic hazard assessment. Ambient-noise windows were processed, spectrally smoothed, and stacked to obtain stable HVSR curves, from which fundamental resonance frequencies and corresponding sediment-thickness estimates were derived. Spatial patterns in these resonance frequencies reveal pronounced basin asymmetry, abrupt lateral …
Impaired Tunability Of Brain State And Motor Dysfunction In A Mouse Model Of Rett Syndrome, Victoria Kindler Norman
Impaired Tunability Of Brain State And Motor Dysfunction In A Mouse Model Of Rett Syndrome, Victoria Kindler Norman
Graduate Theses and Dissertations
Rett syndrome (RTT) is a rare neurological disorder, caused by disrupted function of the MECP2 gene, resulting in impaired cognitive and motor functions. Previous studies suggest that although MECP2 has important functions throughout the body, the etiological origins of RTT-related dysfunction should be sought within the brain. However, it remains a mystery how neural population dynamics are altered in the RTT brain and how these alterations relate to motor dysfunction. Previous studies using an RTT mouse model point to abnormal correlations among firing rates of neurons. Here we hypothesize that such disrupted neural activity correlation could be caused by abnormal …
First-Principles Study Of Uranium Mononitride, Roy Noe Herrera Navarro
First-Principles Study Of Uranium Mononitride, Roy Noe Herrera Navarro
Open Access Theses & Dissertations
This thesis presents a first-principles investigation of uranium mononitride (UN), withemphasis on the connection between uranium 5f electron correlation and defect stability. Electronic-structure calculations were performed within density functional theory using the Vienna Ab initio Simulation Package. Exchange-correlation effects were treated within the generalized gradient approximation, and a Hubbard correction was applied to the uranium 5f manifold. The adopted Hubbard parameter was motivated by first-principles linear-response analysis and considered in the broader context of DFT+DMFT descriptions of correlated uranium systems, including recent interpretations of UN as a Hund-metal system. Bulk UN was studied in unit-cell and 2 x 2 x …
Singularity-Enriched Neural Networks For Elliptic Problems In Polygonal Domains, Harshini Reddy Kodiganti
Singularity-Enriched Neural Networks For Elliptic Problems In Polygonal Domains, Harshini Reddy Kodiganti
Open Access Theses & Dissertations
This thesis develops and analyzes neural-network-based solvers for the Poisson equation on polygonal domains, where re-entrant corners induce reduced solution regularity and challenge standard numerical methods.
Three neural formulations are investigated: Physics-Informed Neural Networks (PINNs), Physics-Informed Extreme Learning Machines (PIELMs), and Rank-Inspired Neural Networks (RINNs). PINNs rely on gradient-based optimization with automatic differentiation, while PIELMs employ randomly initialized hidden features with least-squares training, achieving significantly lower computational cost. RINNs extend this framework through covariance-driven orthogonalization to improve numerical conditioning and stability.
On convex polygonal domains, all three methods are benchmarked against analytical solutions. Both PIELM and RINN consistently achieve higher …
Metabolomics In The Dryland Critical Zone: The Role Of Soil Metabolites In Phosphorus Acquisition, Kalpana Kukreja
Metabolomics In The Dryland Critical Zone: The Role Of Soil Metabolites In Phosphorus Acquisition, Kalpana Kukreja
Open Access Theses & Dissertations
Earth's Critical Zone (CZ) plays a key role in sustaining life through carbon, water, and nutrient cycling from the top of the canopy to the groundwater. A key feature of critical zone research is the integration of multiple interdisciplinary techniques. An emerging set of techniques that can add to this approach is the field of metabolomics, the quantification and study of comprehensive metabolite profiles. In this dissertation, I apply metabolomics to address knowledge gaps in dryland critical zone ecosystems, specifically how soil metabolite dynamics influence biogeochemical processes, and with a particular emphasis on phosphorus (P) cycling in the Chihuahuan Desert. …
Plant Communities Of Arid Ephemeral Stream Streams, Biogeographic Filters, Climatic Sensitivity, Urban Impacts Across Spatial And Temporal Scales, Luis Miranda
Open Access Theses & Dissertations
Ephemeral stream networks, locally known as arroyos, are among the most ecologically significant yet least protected habitats in arid landscapes. Despite supporting a disproportionately high plant biodiversity compared to surrounding uplands, these riparian systems lack regulatory protection in most arid U.S. states and face increasing pressure from urban expansion and intensifying climate change. There is an urgent need to understand how these factors influence riparian plant communities and hinder their ability to recover, enabling effective conservation and management strategies. In this dissertation, I explored the interplay of biogeographic gradients, precipitation variability, and urbanization in shaping arroyo riparian plant communities across …
Understanding Machine Learning Model Behavior Under Fairness And Privacy Constraints, David Anthony Sanchez
Understanding Machine Learning Model Behavior Under Fairness And Privacy Constraints, David Anthony Sanchez
Open Access Theses & Dissertations
Machine learning systems deployed in high-stakes domains are increasingly expected to satisfy demands beyond predictive accuracy-including fairness across demographic groups, protection of sensitive information, and explanations that human stakeholders can inspect and trust. This thesis investigates how those demands can be met through learning frameworks that explicitly govern the relationship between data and models, arguing that trustworthiness is a design problem rather than a post hoc correction. The thesis is organized around three studies, each targeting a distinct point of data-facing control. The first develops CondFairGen, a fairness-aware conditional generator for tabular data that improves subgroup equity by dynamically reweighting …
Eocene To Oligocene Continental Arc Migration In Ecuador And The Origin Of Spatiotemporal Trends In Zircon Lu-Hf Radiogenic Isotopes, Muriel M. Sandoval Vazquez
Eocene To Oligocene Continental Arc Migration In Ecuador And The Origin Of Spatiotemporal Trends In Zircon Lu-Hf Radiogenic Isotopes, Muriel M. Sandoval Vazquez
Open Access Theses & Dissertations
The modern continental arc system in Ecuador is well understood but less is known about arc systems in the past, hindering our understanding of the tectonic evolution of the northern Andes. The Macuchi arc, located in the Western Cordillera of Ecuador, was thought to be the main continental arc system during the Eocene, but new zircon U-Pb LA-ICPMS dates from intrusive arc rocks in central Ecuador indicate a more complex history. During the mid-Eocene, the footprint of arc magmatism broadened and expanded into the Inter-Andean Valley and Eastern Cordillera. During the late Eocene to Oligocene, the arc migrated back toward …
Overcoming Glioblastoma Resistance To Temozolomide With New Derivatives: Design, Synthesis, And Mechanistic Studies, Hualin Zhang
Overcoming Glioblastoma Resistance To Temozolomide With New Derivatives: Design, Synthesis, And Mechanistic Studies, Hualin Zhang
Open Access Theses & Dissertations
Glioblastoma multiforme (GBM) is an aggressive brain tumor with rapid progression and poor prognosis. Although temozolomide (TMZ) remains a central component of standard therapy, its clinical benefit is limited and resistance frequently emerges through DNA repair pathways, particularly O6-methylguanine-DNA methyltransferase (MGMT). Because DNA cross-links are generally more difficult to repair than monoalkylated lesions, we hypothesized that TMZ derivatives bearing protein-reactive functionality might generate damage that is less susceptible to MGMT-mediated resistance. Guided by this rationale, we designed a new class of N3-modified TMZ derivatives containing covalent warheads, developed a synthetic route compatible with the chemical instability of the TMZ scaffold, …
Environmental Movements In El Paso And Ciudad Juarez: Possibilities And Limitations Of Cross-Border Organization At The U.S.-Mexico Border, Vanessa Maria Almada
Environmental Movements In El Paso And Ciudad Juarez: Possibilities And Limitations Of Cross-Border Organization At The U.S.-Mexico Border, Vanessa Maria Almada
Open Access Theses & Dissertations
At the U.S.-Mexico border, the anthropogenic and nationalistic construction of the landscape has accelerated urbanization and unequal development without establishing effective binational institutions for governance over a shared commons. Borderlanders, then, contest unsustainable development with the added complexity of navigating a barrier which creates diverse socioeconomic and political realities that challenge cross-border cooperation. This qualitative research analyzes environmental organizations in El Paso and Ciudad Juarez. Through ethnographic study of mobilization in response to environmental legislation and administrative action in each city, the immediate barriers to cross-border cooperation and limitations of nationalistic institutions in the borderlands can be better understood.
Exhumation Of The Pelona-Orocopia-Rand Schist And Fault Kinematic Constraints On Evolution Of The Eastern California Shear Zone, James Boyette Barker
Exhumation Of The Pelona-Orocopia-Rand Schist And Fault Kinematic Constraints On Evolution Of The Eastern California Shear Zone, James Boyette Barker
Open Access Theses & Dissertations
Southeastern California has experienced a complex recent geologic history as it continues to evolve from a convergent boundary to a period of NE-directed extension and evolution of the Eastern California Shear Zone (ECSZ). This transition is recorded in exhumed bodies of Pelona-Orocopia-Rand (POR) schist and in changing styles of fault deformation. This thesis has two interrelated goals. First, I aim to refine the timing of transition from NE extension to NS contraction in the ECSZ of southeastern California by integrating (U-Th)/He thermochronology with field-based structural analysis. The second prong of this study is to constrain broader patterns of POR schist …
Exploring Connectivity And Element Distribution In The Critical Zone Using Deep Cores Below Agricultural And Natural Drylands In The American Southwest, Angie Lynette Cano
Exploring Connectivity And Element Distribution In The Critical Zone Using Deep Cores Below Agricultural And Natural Drylands In The American Southwest, Angie Lynette Cano
Open Access Theses & Dissertations
Water movement controls how solutes are transported and stored in arid Critical Zone (CZ) systems. In natural drylands, low precipitation and high evapotranspiration lead to long term salt accumulation in the CZ, whereas irrigation increases water input and increases downward solute transport. This study investigates how agricultural practices alter subsurface hydrology and geochemistry by comparing two deep CZ cores from the southwestern United States: a 50 m deep core beneath a flood irrigated pecan farm named 5R farm, in the Rio Grande Valley in Tornillo, Texas, and a 97.5 m deep core from the Red Lake Playa in the Jornada …
Timing And Synchronization: Software And Hardware Approaches For Precision Maximizing, Christina Alicia Alejandra Carreon Jimenez
Timing And Synchronization: Software And Hardware Approaches For Precision Maximizing, Christina Alicia Alejandra Carreon Jimenez
Open Access Theses & Dissertations
This thesis explores the design of synchronization mechanisms that allow multiple FPGA boards to operate as if they were a single coherent timing domain. The solutions span three layers: a software PLL for E1 telecommunication links, a PCIe-based timestamp exchange protocol, and a hardware-level multi-FPGA mesh architecture. Across these layers, the work demonstrates that practical, low-cost synchronization can achieve sub-microsecond accuracy without the burden of specialized hardware such as GPSDOs or White Rabbit infrastructure. Experiments show stable alignment within the nanosecond-microsecond range, validating the feasibility of the proposed methods for SDR and telecom applications.
Enhancing Walleye (Ogaa) Recruitment: Evaluating Assisted Reproduction As A Mitigation Strategy, Douglass Keiser
Enhancing Walleye (Ogaa) Recruitment: Evaluating Assisted Reproduction As A Mitigation Strategy, Douglass Keiser
Biology Graduate Theses
Over the past several decades, cold- and cool-water fish populations across the Upper Midwest, including Minnesota and Wisconsin, have shown troubling signs of decline. Among the most affected is the walleye/Ogaa (Sander vitreus), a species deeply embedded in the ecological balance, cultural identity, and economic vitality of the region, and central to the lifeways, treaty-reserved rights, and resource stewardship of Tribal Nations, including Ojibwe communities across the Upper Midwest. Despite ongoing stocking efforts and harvest regulations, many lake systems have experienced persistent declines in natural recruitment, prompting resource agencies to investigate the underlying causes. One such system is …
Degradation And Metabolic Analysis Of Synthesized Quorum-Sensing Signals By The Model Eukaryote Chlamydomonas Reinhardtii, Adam Josef Bach
Degradation And Metabolic Analysis Of Synthesized Quorum-Sensing Signals By The Model Eukaryote Chlamydomonas Reinhardtii, Adam Josef Bach
Theses and Dissertations
Bacterial organisms can “talk” with one another on a colony-wide scale using a communication system known as quorum-sensing (QS) via chemical signals. These signals are produced at a basal rate throughout the life of the bacteria and are classified as autoinducers, which diffuse across the cell membrane. Once the critical concentration is reached, they begin to diffuse back into the cell and initiate a phenotypic change. As these signals exist outside the membrane of their producer, they are also accessible to other organisms. It has already been noted that some plant species uptake these compounds through their roots and break …
Aircraft Fault Detection Via Weight And Bias Analysis Of A Custom First Neural Network Layer, George Harrison Chen
Aircraft Fault Detection Via Weight And Bias Analysis Of A Custom First Neural Network Layer, George Harrison Chen
Theses and Dissertations
Fault detection in aircraft is traditionally handled through redundant hardware and comparison algorithms to detect failures. Alternatives like model-based residual generation and data-driven approaches such as supervised fault classification and unsupervised anomaly detection have been explored, but they suffer from practical limitations; model-based methods require accurate system models, and data-driven methods have large constraints on the data limiting scalability and adaptability. This work presents a purely data-driven neural network architecture featuring a custom first layer designed for real-time fault detection where the weights and biases of this layer are used to detect faults. The network requires zero supervision and complements …
Design And Simulation Of Anti-Resonant Hollow-Core Fiber For Sensing Applications, Pravallika Kante
Design And Simulation Of Anti-Resonant Hollow-Core Fiber For Sensing Applications, Pravallika Kante
Theses and Dissertations
This thesis presents the design and simulation of an 8-tube single-ring anti-resonant hollow-core fiber for sensing applications, with particular emphasis on methane gas detection at the fundamental absorption wavelength of 3.3 µm. Conventional solid-core silica optical fibers exhibit strong multi-phonon material absorption beyond 2.5 µm, rendering them fundamentally unsuitable for efficient light guidance and direct gas sensing at mid-infrared wavelengths. Anti-resonant hollow-core fibers overcome this limitation by guiding light predominantly through an air-filled hollow core via the anti-resonant reflecting optical waveguide mechanism, in which the thin silica glass walls of the cladding tubes act as Fabry-Pérot etalons that confine the …
Adaptive Artificial Potential Field Guidance And Control For Autonomous Docking With Uncooperative And Unknown Spacecraft, Steven Holmberg
Adaptive Artificial Potential Field Guidance And Control For Autonomous Docking With Uncooperative And Unknown Spacecraft, Steven Holmberg
Theses and Dissertations
The increasing demand for on-orbit servicing (OOS), active debris removal (ADR), and space domain awareness (SDA) missions has increased the need for autonomous spacecraft rendezvous and proximity operations (RPO) with uncooperative and unknown targets. Traditional guidance and control methods are typically designed for cooperative systems with known geometry and state information. This work builds on previous research to develop and evaluate an artificial potential field (APF)-based control framework capable of autonomous operation with minimal prior target knowledge and applicability to both relatively static and tumbling spacecraft.
The proposed APF formulation incorporates established safety constructs from cooperative docking systems, including an …
Weavecc: Symbolically-Guided Joint Exploration Of Inputs And Schedules For Concurrency Bug Detection, William Philip Dinauer
Weavecc: Symbolically-Guided Joint Exploration Of Inputs And Schedules For Concurrency Bug Detection, William Philip Dinauer
Dartmouth College Master’s Theses
Concurrent programs introduce a class of bugs that depend jointly on both program inputs and thread schedules. Exposing these bugs requires simultaneously reasoning about which code paths are reachable and which thread interleavings are possible. At the same time, many existing tools handle the problem insufficiently. Race detectors observe only the interleavings that the OS happens to produce. Fuzzers explore inputs without controlling schedules. Tools that address both dimensions together exist, but are built on interpretation-based symbolic executors that incur considerable overhead.
We present WeaveCC, a practical concurrency testing tool for C/C++ programs that jointly explores inputs and thread schedules. …
Exploring The Evolution Of Preservice Elementary Teachers' Mathematics Identity And Possible Selves: A Multi-Case Study Approach, Christa R. Mawn
Exploring The Evolution Of Preservice Elementary Teachers' Mathematics Identity And Possible Selves: A Multi-Case Study Approach, Christa R. Mawn
Theses, Dissertations and Culminating Projects
This study explores the nature of preservice elementary teachers’ mathematics identity and possible selves and identifies shifts in their mathematics identity or possible selves over the course of a place value unit during the semester during a course on mathematics content for elementary teachers. Drawing on narrative identity and possible selves theory, this qualitative multi-case study examined the mathematics identity and possible selves of preservice elementary teachers enrolled in a mathematics content course. Course assignments were used as data sources and included written narratives, future-oriented reflections, drawings, and course artifacts. Individual cases were analyzed, and were followed by a cross-cases …
Fret Studies On The Binding Of Fibroblast Growth Factor (Fgf) Proteins To The Hard Corona Of Cuins2-Based Quantum Dots, Colette Robinson
Fret Studies On The Binding Of Fibroblast Growth Factor (Fgf) Proteins To The Hard Corona Of Cuins2-Based Quantum Dots, Colette Robinson
Graduate Theses and Dissertations
Fibroblast Growth Factor (FGF) has been shown to be an important protein in angiogenesis, which is critical in developmental biology and wound healing but has also been implicated in cancer metastasis. FGF interacts with an FGF Receptor (FGFR) to signal the onset of angiogenesis but the detailed mechanism of angiogenesis, and particularly its regulation, is still largely unknown. Imaging the interaction of FGF with FGFR in biologically-relevant environments, such as directly in cells, is key towards furthering this understanding and may eventually aid in the development of better cancer treatments. CuInS2/ZnS quantum dots (QDs) are an attractive fluorescent probe to …