Physical Sciences and Mathematics Commons^™

Conformal Bk Equation At Qcd Wilson-Fisher Point, I. Balitsky, G. A. Chirilli

Physics Faculty Publications

High-energy scattering in pQCD in the Regge limit is described by the evolution of Wilson lines governed by the BK equation [1, 2]. In the leading order, the BK equation is conformally invariant and the eigenfunctions of the linearized BFKL equation are powers. It is a common belief that at d ≠ 4 the BFKL equation is useless since unlike d = 4 case it cannot be solved by usual methods. However, we demonstrate that at critical Wilson-Fisher point of QCD the relevant part of NLO BK restores the conformal invariance so the solutions are again powers. As a check …

Dual-Energy Electron Storage Ring, B. Dhital, Y. S. Derbenev, A. Hutton, H. Zhang, G. A. Krafft, Y. Zhang, F. Lin, V. S. Morozov

Physics Faculty Publications

A dual-energy electron storage ring is a novel concept initially proposed to cool hadron beams at high energies. The design consists of two closed rings operating at significantly different energies: the low-energy ring and the high-energy ring. These two rings are connected by an energy recovery linac (ERL) that provides the necessary energy difference. The ERL features superconducting radio-frequency (SRF) cavities that first accelerate the beam from the low energy E_L to the high energy E_H and then decelerate the beam from E_H to E_L in the next pass. The different SRF cavities in the ERL …

Crabbing Cavity System Development For International Linear Collider, Subashini De Silva

Physics Faculty Publications

The International Liner Collider requires a crabbing system to increase the luminosity of the colliding electron bunches. The ILC has a large crossing angle that requires compensation in order to meet the luminosity requirements. There are several frequency options proposed for the crabbing cavity design. Two crab cavity designs were selected to be prototyped in the pre-lab phase, following the Down Selection Review on Crab Cavity Design held in April 2023. The two rf designs selected are the 1.3 GHz rf-dipole cavity and the 2.6 GHz QMiR cavity. We will be presenting the electromagnetic and mechanical design details of the …

Event Generators For High-Energy Physics Experiments, J. M. Campbell, M. Diefenthaler, T. J. Hobbs, S. Höche, J. Isaacson, F. Kling, S. Mrenna, J. Reuter, S. Alioli, J. R. Andersen, C. Andreaopoulos, A. M. Ankowski, E.C. Aschenauer, A. Ashkenazi, M. D. Baker, J. L. Barrow, M. Van Beekveld, G. Beswick, S. Bhattacharya, K. Zapp, Et Al.

Physics Faculty Publications

We provide an overview of the status of Monte-Carlo event generators for high-energy particle physics. Guided by the experimental needs and requirements, we highlight areas of active development, and opportunities for future improvements. Particular emphasis is given to physics models and algorithms that are employed across a variety of experiments. These common themes in event generator development lead to a more comprehensive understanding of physics at the highest energies and intensities, and allow models to be tested against a wealth of data that have been accumulated over the past decades. A cohesive approach to event generator development will allow these …

First Measurement Of Deeply Virtual Compton Scattering On The Neutron With Detection Of The Active Neutron, A. Hobart, S. Niccolai, M. Čuic, K. Kumerički, P. Achenbach, J. S. Alvarado, W. R. Armstrong, H. Atac, H. Avakian, L. Baashen, N. A. Baltzell, L. Barion, M. Bashkanov, M. Battaglieri, M. Benkel, F. Benmokhtar, A. Bianconi, A. S. Biselli, S. Boiarinov, M. Zurek, Et Al.

Physics Faculty Publications

Measuring deeply virtual Compton scattering (DVCS) on the neutron is one of the necessary steps to understand the structure of the nucleon in terms of generalized parton distributions (GPDs). Neutron targets play a complementary role to transversely polarized proton targets in the determination of the GPD 𝐸. This poorly known and poorly constrained GPD is essential to obtain the contribution of the quarks’ angular momentum to the spin of the nucleon. DVCS on the neutron was measured for the first time selecting the exclusive final state by detecting the neutron, using the Jefferson Lab longitudinally polarized electron beam, with energies …

Toward A Unified Description Of Hadron Scattering At All Energies, D. Stamen, D. Winney, A. Rodas, C. Fernandez-Ramirez, V. Mathieu, G. Montaña, A. Pilloni, A. P. Szczepaniak

Physics Faculty Publications

The construction of general amplitudes satisfying symmetries and 𝑆-matrix constraints has been the primary tool in studying the spectrum of hadrons for over half a century. In this work, we present a new parametrization, which can fulfill many expectations of 𝑆-matrix and Regge theory and connects the essential physics of hadron scattering in the resonance region and in asymptotic limits. In this construction, dynamical information is entirely contained in Regge trajectories that generalize resonance poles in the complex energy plane to moving poles in the angular momentum plane. We highlight the salient features of the model, compare with existing literature …

Revisiting Gauge Invariance And Reggeization Of Pion Exchange, Glòria Montaña, Daniel Winney, Łukasz Bibrzycki, César Fernández-Ramirez, Giorgio Foti, Nadine Hammoud, Vincent Mathieu, Robert J. Perry, Alessandro Pilloni, Arkaitz Rodas, Vanamali Shastry, Wyatt A. Smith, Adam P. Szczepaniak

Physics Faculty Publications

The Reggeized pion is expected to provide the main contribution to the forward cross section in light meson photoproduction reactions with charge exchange at high energies. We discuss the Reggeization of pion exchange in charged pion photoproduction with an emphasis on consistency with current conservation. We show that the gauge-invariant amplitude for the exchange of a particle with a generic even spin J ≥ 2 in the t channel is analytic at J = 0 and that it can be interpreted in terms of the nucleon electric current. This enables us to reconcile the dynamics in the s and u …

A Scoping Review On Mobile Health Technology For Assessment And Intervention Of Upper Limb Motor Function In Children With Motor Impairments, Md Raihan Mia, Sheikh Iqbal Ahamed, Alissa V. Fial, Samuel Nemanich

Computer Science Faculty Research and Publications

Upper limb (UL) motor dysfunctions impact residual movement in hands/shoulders and limit participation in play, sports, and leisure activities. Clinical and laboratory assessments of UL movement can be time-intensive, subjective, and/or require specialized equipment and may not optimally capture a child's motor abilities. The restrictions to in-person research experienced during the COVID-19 pandemic have inspired investigators to design inclusive at-home studies with child participants and their families. Relying on the ubiquity of mobile devices, mobile health (mHealth) applications offer solutions for various clinical and research problems. This scoping review article aimed to aggregate and synthesize existing research that used health …

Remember The Human: A Systematic Review Of Ethical Considerations In Reddit Research, Casey Fiesler, Michael Zimmer, Nicholas Proferes, Sarah A. Gilbert, Naiyan Jones

Computer Science Faculty Research and Publications

Reddit is one of the world's most prominent social media platforms, and also a valuable source of data for internet researchers. However, working with this kind of data also presents novel ethical complications for researchers, including issues around privacy, vulnerable populations, and unintended consequences. This paper describes an analysis of 134 papers that rely on Reddit data while also including some discussion of ethical implications and/or considerations by the researchers. Our analysis of these papers reveals common ethical issues and ethically motivated methodological decisions, as described by the researchers themselves, while also exposing some gaps for further ethical contemplation for …

Voiceattack: Fingerprinting Voice Command On Vpn-Protected Smart Home Speakers, Xiaoguang Guo, Keyang Yu, Qi Li, Dong Chen

Computer Science Faculty Research and Publications

Recently, there are growing security and privacy concerns regarding smart voice speakers, such as Amazon Alexa and Google Home. Extensive prior research has shown that it is surprisingly easy to infer Amazon Alexa voice commands over their network traffic data. To prevent these traffic analytics (TA)-based inference attacks, smart home owners are considering deploying virtual private networks (VPNs) to safeguard their smart speakers. In this work, we design a new machine learning (ML) and deep learning (DL)-powered attack framework---VoiceAttack that could still accurately fingerprint voice commands on VPN-encrypted voice speaker network traffic. We evaluate VoiceAttack under 5 different real-world settings …

Student Attitudes And Intentions To Use Continuous Authentication Methods Applied To Mitigate Impersonation Attacks During E-Assessments, Andrea E. Green

CCAC Theses and Dissertations

No solution can ultimately eliminate cheating in online courses. However, universities reserve funding for authentication systems to minimize the threat of cheating in online courses. Most higher education institutions use a combination of authentication methods to secure systems against impersonation attacks during online examinations. Authentication technologies ensure that an online course is protected from impersonation attacks. However, it is important that authentication methods secure systems against impersonation attacks with minimal disruption during an examination. Authentication methods applied to secure e-assessments against impersonation attacks may impact a student’s attitude and intentions to use the e-examination system.

In this regard, the research …

Assessing Organizational Investments In Cybersecurity And Financial Performance Before And After Data Breach Incidents Of Cloud Saas Platforms, Munther B. Ghazawneh

CCAC Theses and Dissertations

Prior research indicated that providing inappropriate investment in organizations for Information Technology (IT) security makes these organizations suffer from IT security issues that may cause data breach incidents. Data breaches in cloud Software as a Service (SaaS) platforms lead to the disclosure of sensitive information, which causes disruption of services, damage to the organizational image, or financial losses. Massive data breaches still exist in cloud SaaS platforms which result in data leaks and data theft of customers in organizations.

IT security risks and vulnerabilities cost organizations millions of dollars a year as organizations may face an increase in cybersecurity challenges. …

Development Of Cybersecurity Footprint Index For Manufacturing Companies To Assess Organizational Cyber Posture, John A. Del Vecchio

CCAC Theses and Dissertations

With the continued changes in how businesses work, cyber-attack targets are constantly in flux between organizations, individuals, and various aspects of the supply chain of interconnected companies delivering goods and services. As one of the 16 critical infrastructure sectors, manufacturing is known for complex integrated Information Systems (ISs) incorporated heavily into production operations. Many of these ISs are procured and supported by third parties, also called interconnected entities in the supply chain. Disruptions to manufacturing companies would not only have significant financial losses but would also have economic and safety impacts on society. The vulnerabilities of interconnected companies create inherited …

Enhancing Sentiment Analysis In Niche Domains: Introducing Diverse Datasets And Evaluating Model Performance In Car Dealership And Board Game Reviews, Kimon Andreou

CCAC Theses and Dissertations

The field of Natural Language Processing (NLP) has witnessed significant advancements in recent decades, with text classification emerging as a critical task, particularly in sentiment analysis applications. However, a constant challenge within sentiment analysis research is the scarcity of diverse and specialized labeled datasets. The present dissertation addresses this gap by developing two novel, labeled textual datasets sourced from niche areas: BoardGameGeek.com's top 250 board game reviews and TrustPilot.com's car dealership reviews

The main goal of this dissertation is to enrich sentiment analysis methodologies by providing unique datasets and insights into the performance of current models within specialized domains. By …

A Use Case Of Chatgpt: Summary Of An Expert Panel Discussion On Electronic Health Records And Implementation Science, Seppo T Rinne, Julian Brunner, Timothy P Hogan, Jacqueline M Ferguson, Drew A Helmer, Sylvia J Hysong, Grace Mckee, Amanda Midboe, Megan E Shepherd-Banigan, A Rani Elwy

Center for Medical Ethics and Health Policy Staff Publications

Objective: Artificial intelligence (AI) is revolutionizing healthcare, but less is known about how it may facilitate methodological innovations in research settings. In this manuscript, we describe a novel use of AI in summarizing and reporting qualitative data generated from an expert panel discussion about the role of electronic health records (EHRs) in implementation science.

Materials and methods: 15 implementation scientists participated in an hour-long expert panel discussion addressing how EHRs can support implementation strategies, measure implementation outcomes, and influence implementation science. Notes from the discussion were synthesized by ChatGPT (a large language model-LLM) to generate a manuscript summarizing the discussion, …

Erratum: Toward Standardization, Harmonization, And Integration Of Social Determinants Of Health Data: A Texas Clinical And Translational Science Award Institutions Collaboration - Corrigendum, Byeong Yeob Choi, Robert L Ferrer, Jonathan A Gelfond, Sandi L Pruitt, Vaishnavi Kannan, Paula K Shireman, Heidi Spratt, Kayla J Torres Morales, Chen-Pin Wang, Zhan Wang, Meredith N Zozus, Edward C Sankary, Susanne Schmidt

Faculty, Staff and Student Publications

This corrects the article "Toward standardization, harmonization, and integration of social determinants of health data: A Texas Clinical and Translational Science Award institutions collaboration" in volume 8, e17.

A Real-World Disproportionality Analysis Of Everolimus: Data Mining Of The Public Version Of Fda Adverse Event Reporting System, Shu Liu, Lan Luo

Faculty, Staff and Student Publications

Background: Everolimus is an inhibitor of the mammalian target of rapamycin and is used to treat various tumors. The presented study aimed to evaluate the Everolimus-associated adverse events (AEs) through data mining of the US Food and Drug Administration Adverse Event Reporting System (FAERS).

Methods: The AE records were selected by searching the FDA Adverse Event Reporting System database from the first quarter of 2009 to the first quarter of 2022. Potential adverse event signals were mined using the disproportionality analysis, including reporting odds ratio the proportional reporting ratio the Bayesian confidence propagation neural network and the empirical Bayes geometric …

An Automated Approach For Identifying Erroneous Is-A Relations In Snomed Ct

Faculty, Staff and Student Publications

SNOMED CT is the most comprehensive clinical terminology employed worldwide and enhancing its accuracy is of utmost importance. In this work, we introduce an automated approach to identifying erroneous IS-A relations in SNOMED CT. We first extract linked concept-pairs from which we generate Term Difference Pairs (TDPs) that contain differences between the concepts. Given a TDP, if the reversed TDP also exists and the number of linked-pairs generating this TDP is less than those generating the reversed TDP, then we suggest the former linked-pairs as potentially erroneous IS-A relations. We applied this approach to the Clinical finding and Procedure subhierarchies …

Linking Artificial Sweetener Intake With Kidney Function: Insights From Nhanes 2003-2006 And Findings From Mendelian Randomization Research, Zhenjiang Zhang, Huijie Li, Xuhan Li, Jing Song, Li Zhang, Ran Zhang, Chang Lu, Yang Gong, Jian Gong

Faculty, Staff and Student Publications

BACKGROUND: The current investigation examines the association between artificial sweetener (AS) consumption and the likelihood of developing chronic kidney disease (CKD), along with its impact on kidney function.

METHODS: We utilized data from the National Health and Nutrition Examination Survey from 2003-2006 to conduct covariance analysis and weighted adjusted logistic regression, aiming to assess the association between artificial sweetener intake and CKD risk, as well as kidney function indicators. Subsequently, we employed Mendelian randomization methods to validate the causal relationship between the intake of artificial sweeteners, CKD risk, and kidney function indicators. Instrumental variable analysis using inverse-variance weighting and Robust …

Siglec15, Negatively Correlated With Pd-L1 In Hcc, Could Induce Cd8+ T Cell Apoptosis To Promote Immune Evasion, Qiang Yu, Shuang Liu, Binghai Zhou, Jiuliang Yan, Wentao Zhang, Xiaoqiang Li, Yongfeng Xu, Yongsheng Xiao, Jian Zhou, Jia Fan, Mien-Chie Hung, Qinghai Ye, Hui Li, Lei Guo

Faculty, Staff and Student Publications

Functional roles of SIGLEC15 in hepatocellular carcinoma (HCC) were not clear, which was recently found to be an immune inhibitor with similar structure of inhibitory B7 family members. SIGLEC15 expression in HCC was explored in public databases and further examined by PCR analysis. SIGLEC15 and PD-L1 expression patterns were examined in HCC samples through immunohistochemistry. SIGLEC15 expression was knocked-down or over-expressed in HCC cell lines, and CCK8 tests were used to examine cell proliferative ability in vitro. Influences of SIGLEC15 expression on tumor growth were examined in immune deficient and immunocompetent mice respectively. Co-culture system of HCC cell lines and …

Modernizing And Harmonizing Regulatory Data Requirements For Genetically Modified Crops-Perspectives From A Workshop, Ming Hua Huang, Debbie Mahadeo, Carey A Mathesius, Mitscheli Sanches Da Rocha, Shuang Song, Ewa Urbanczyk-Wochniak

Faculty, Staff and Student Publications

Genetically modified (GM) crops that have been engineered to express transgenes have been in commercial use since 1995 and are annually grown on 200 million hectares globally. These crops have provided documented benefits to food security, rural economies, and the environment, with no substantiated case of food, feed, or environmental harm attributable to cultivation or consumption. Despite this extensive history of advantages and safety, the level of regulatory scrutiny has continually increased, placing undue burdens on regulators, developers, and society, while reinforcing consumer distrust of the technology. CropLife International held a workshop at the 16th International Society of Biosafety Research …

Vagus Nerve Stimulation For The Therapy Of Dravet Syndrome: A Systematic Review And Meta-Analysis

Faculty, Staff and Student Publications

OBJECTIVE: Dravet syndrome (DS) is a refractory developmental and epileptic encephalopathy characterized by seizures, developmental delay and cognitive impairment with a variety of comorbidities, including autism-like behavior, speech dysfunction, and ataxia. Vagus nerve stimulation (VNS) is one of the common therapies for DS. Here, we aim to perform a meta-analysis and systematic review of the efficacy of VNS in DS patients.

METHODS: We systematically searched four databases (PubMed, Embase, Cochrane and CNKI) to identify potentially eligible studies from their inception to January 2024. These studies provided the effective rate of VNS in treating patients with DS. The proportions of DS …

Prioritizing Clinically Significant Lung Cancer Somatic Mutations For Targeted Therapy Through Efficient Ngs Data Filtering System

Faculty, Staff and Student Publications

In the realm of lung cancer treatment, where genetic heterogeneity presents formidable challenges, precision oncology demands an exacting approach to identify and hierarchically sort clinically significant somatic mutations. Current Next-Generation Sequencing (NGS) data filtering pipelines, while utilizing various external databases for mutation screening, often fall short in comprehensive integration and flexibility needed to keep pace with the evolving landscape of clinical data. Our study introduces a sophisticated NGS data filtering system, which not only aggregates but effectively synergizes diverse data sources, encompassing genetic variants, gene functions, clinical evidence, and an extensive body of literature. This system is distinguished by a …

Linking Cancer Clinical Trials To Their Result Publications

Faculty, Staff and Student Publications

The results of clinical trials are a valuable source of evidence for researchers, policy makers, and healthcare professionals. However, online trial registries do not always contain links to the publications that report on their results, instead requiring a time-consuming manual search. Here, we explored the application of pre-trained transformer-based language models to automatically identify result-reporting publications of cancer clinical trials by computing dense vectors and performing semantic search. Models were fine-tuned on text data from trial registry fields and article metadata using a contrastive learning approach. The best performing model was PubMedBERT, which achieved a mean average precision of 0.592 …

Sequencing Conversational Turns In Peer Interactions: An Integrated Approach For Evidence-Based Conversational Agent For Just-In-Time Nicotine Cravings Intervention

Faculty, Staff and Student Publications

BACKGROUND: Risky health behaviors place an enormous toll on public health systems. While relapse prevention support is integrated with most behavior modification programs, the results are suboptimal. Recent advances in artificial intelligence (AI) applications provide us with unique opportunities to develop just-in-time adaptive behavior change solutions.

METHODS: In this study, we present an innovative framework, grounded in behavioral theory, and enhanced with social media sequencing and communications scenario builder to architect a conversational agent (CA) specialized in the prevention of relapses in the context of tobacco cessation. We modeled peer interaction data (n = 1000) using the taxonomy of behavior …

Community Scientist Program Provides Bi-Directional Communication And Co-Learning Between Researchers And Community Members, Erica Cantu, Chelsea C Carrier, Chiamaka D Chukwu, Cassandra L Harris, Luz K Melendez, Crystal L Roberson, Angela M Ross, Sophia C Russell, Pablo Sanchez, Amirali Tahanan, Blair C Zdenek, Belinda M Reininger, Lorna H Mcneill

Faculty, Staff and Student Publications

Community involvement in research is key to translating science into practice, and new approaches to engaging community members in research design and implementation are needed. The Community Scientist Program, established at the MD Anderson Cancer Center in Houston in 2018 and expanded to two other Texas institutions in 2021, provides researchers with rapid feedback from community members on study feasibility and design, cultural appropriateness, participant recruitment, and research implementation. This paper aims to describe the Community Scientist Program and assess Community Scientists' and researchers' satisfaction with the program. We present the analysis of the data collected from 116 Community Scientists …

Effect Of S-Ketamine On Postoperative Nausea And Vomiting In Patients Undergoing Video-Assisted Thoracic Surgery: A Randomized Controlled Trial, Weihua Li, Long Wang, Haijun Xu, Miao Zhang, Dunpeng Yang, Liwei Wang, Hai Zhou

Faculty, Staff and Student Publications

PURPOSE: Postoperative nausea and vomiting (PONV) frequently occur in patients after surgery. In this study, the authors investigated whether perioperative S-ketamine infusion could decrease the incidence of PONV in patients undergoing video-assisted thoracoscopic surgery (VATS) lobectomy.

PATIENTS AND METHODS: This prospective, randomized, double-blinded, controlled study was conducted a total of 420 patients from September 2021 to May 2023 at Xuzhou Central Hospital in China, who underwent elective VATS lobectomy under general anesthesia with tracheal intubation. The patients were randomly assigned to either the S-ketamine group or the control group. The S-ketamine group received a bolus injection of 0.5 mg/kg S-ketamine …

Human Equilibrative Nucleoside Transporter 1: Novel Biomarker And Prognostic Indicator For Patients With Gemcitabine-Treated Pancreatic Cancer, Yicheng Wang, Jiangdong Qiu, Yueze Liu, Lei You, Lianfang Zheng, Taiping Zhang

Faculty, Staff and Student Publications

AIM: This article aimed to find appropriate pancreatic cancer (PC) patients to treat with Gemcitabine with better survival outcomes by detecting hENT1 levels.

METHODS: We collected surgical pathological tissues from PC patients who received radical surgery in our hospital from September 2004 to December 2014. A total of 375 PC tissues and paired adjacent nontumor tissues were employed for the construction of 4 tissue microarrays (TMAs). The quality of the 4 TMAs was examined by HE staining. We performed immunohistochemistry analysis to evaluate hENT1 expression in the TMAs. Moreover, we detected hENT1 expression level and proved the role of hENT1 …

Visualsphere: A Web-Based Interactive Visualization System For Clinical Research Data, Xiaojin Li

Faculty, Staff and Student Publications

Clinical research data visualization is integral to making sense of biomedical research and healthcare data. The complexity and diversity of data, along with the need for solid programming skills, can hinder advances in clinical research data visualization. To overcome these challenges, we introduce VisualSphere, a web-based interactive visualization system that directly interfaces with clinical research data repositories, streamlining and simplifying the visualization workflow. VisualSphere is founded on three primary component modules: Connection, Configuration, and Visualization. An end-user can set up connections to the data repositories, create charts by selecting the desired tables and variables, and render visualization dashboards generated by …

Xuebijing Improves Intestinal Microcirculation Dysfunction In Septic Rats By Regulating The Vegf-A/Pi3k/Akt Signaling Pathway, Nan Gao, Sheng-Tao Yan, Guo-Qiang Zhang

Faculty, Staff and Student Publications

BACKGROUND: This study aims to explore whether Xuebijing (XBJ) can improve intestinal microcirculation dysfunction in sepsis and its mechanism.

METHODS: A rat model of sepsis was established by cecal ligation and puncture (CLP). A total of 30 male SD rats were divided into four groups: sham group, CLP group, XBJ + axitinib group, and XBJ group. XBJ was intraperitoneally injected 2 h before CLP. Hemodynamic data (blood pressure and heart rate) were recorded. The intestinal microcirculation data of the rats were analyzed via microcirculation imaging. Enzyme-linked immunosorbent assay (ELISA) kits were used to detect the serum levels of interleukin-6 (IL-6), …