Physical Sciences and Mathematics Commons^™

A Complete Transfer Learning-Based Pipeline For Discriminating Between Select Pathogenic Yeasts From Microscopy Photographs, Ryan A. Parker, Danielle S. Hannagan, Jan H. Strydom, Christopher J. Boon, Jessica Fussell, Chelbie A. Mitchell, Katie L. Moerschel, Aura G. Valter-Franco, Christopher Cornelison

Faculty Articles

Pathogenic yeasts are an increasing concern in healthcare, with species like Candida auris often displaying drug resistance and causing high mortality in immunocompromised patients. The need for rapid and accessible diagnostic methods for accurate yeast identification is critical, especially in resource-limited settings. This study presents a convolutional neural network (CNN)-based approach for classifying pathogenic yeast species from microscopy images. Using transfer learning, we trained the model to identify six yeast species from simple micrographs, achieving high classification accuracy (93.91% at the patch level, 99.09% at the whole image level) and low misclassification rates across species, with the best performing model. …

Ai And Ethical Use Implication For Research, Kelley Plass, Sierra Campbell

May Institute

Artificial intelligence (AI) is becoming increasingly integrated into our daily lives, especially for students. While there are valid debates about the advantages and disadvantages of students using AI for their assignments, such as comparing tools like Grammarly and ChatGPT, one aspect that often goes unexamined is the information sources that AI relies on. AI is now integrated into search engines like Google and Bing, making it accessible to everyone. Additionally, with the emergence of AI research tools like ResearchRabbit, AI's role in everyday activities continues to expand beyond easily accessible resources such as subscription databases. AI is now an optional …

Ph Dependent Structural Characterization Of Ich Ensembles Needed For Catalysis, Kevin C. Prososki

Honors Program: Senior Projects (Public)

No abstract provided.

Research On Grey-Box Modeling Method Of Digital Twins For Cantilever Structure, Wenjia Zhang, Heming Zhang

Journal of System Simulation

Abstract: The construction of accurate and highly real-time digital twin models in complex industrial setting presents several challenges. Traditional model construction approaches based only on mechanism or data show certain limitations. Therefore, this study is based on the idea of grey-box modeling, taking the cantilever structure within a boom-type roadheader as the object, and proposes a novel modeling approach that combines the characteristics of the mechanism model and introduces a self-attention mechanism. This method performs grayscale transformation on the original input and splices it with physical features to achieve organic fusion of mechanism information, which not only enhances the expressiveness …

An Extended Image Features Based Uncalibrated Visual Servoing Method, Shuzhen Zhang, Yukun Cheng, Yangbo Liu, Fusheng Zha

Journal of System Simulation

Abstract: Aiming at the traditional uncalibrated visual servo relying on the estimation of image Jacobi matrix and the coupling of the motion of each degree of freedom of the camera, on the basis of imagebased uncalibrated visual servo, an extended image features based uncalibrated visual servo method is proposed. By analyzing the relationship between image features and camera frames change in the visual servoing process, the visual servoing process in the image space is decomposed into four basic processes: translation, stretching, rotation and scaling; by analyzing the changing of image features in the visual servoing process, extended image features are …

A Modeling And Simulation Method For Firepower Intelligent Decision-Making Of Directed Energy System Basedon Joint Dqn, Changhong Qu, Junjie Wang, Kun Wang, Qingyong Cui, Jiangyang Chen, Xinpeng Wang

Journal of System Simulation

Abstract: In order to solve the problem of dynamically addressing firepower intelligent decision-making in anti-UAV cluster combat using a directed energy system, a deep reinforcement learning model is established. Based on the high multi-agent state and action space dimensions of this model, a modeling and simulation method of firepower intelligent decision-making of directed energy system based on joint deep Q network (DQN) is proposed. The state space is constructed from the state of directed energy system, UAV cluster and the directed energy system deployment area. The joint mechanism is used to share the state information of each equipment and the …

Research On Modeling, Optimization And Application Of Aeroengine Oil System, Shijie Huang, Zhensheng Zhang, Jing Cai, Rui Zhang

Journal of System Simulation

Abstract: In response to the high cost and long cycle of using experimental methods for monitoring, diagnosing, and predicting lubricating oil system, a simulation model for oil system is constructed and optimized, and the application of the model in health management of oil system is proposed. Based on the physical characteristics of the components in the oil system, subsystem models for ventilation, oil supply, thermodynamics, and oil return are constructed using a certain engine oil system as an example, and the whole oil system model is constructed and solved iteratively. The model is optimized by combining particle swarm optimization and …

Adaptive Multi-Scale Feature Pyramid Network For Occlusion Pedestrian Detection, Huaping Zhou, Tao Wu, Kelei Sun

Journal of System Simulation

Abstract: To address the issue of current pedestrian detectors, which struggle to extract complete features in occlusion-heavy environments and consequently have low detection accuracy. A novel adaptive multiscale feature pyramid network is proposed. A multi-scale feature enhancement module (MFEM) is developed. It captures the visible area of pedestrians at different scales through a multi-branch network with different receptive fields. An AFM (adaptive fusion module) is proposed. It calculates the importance of different pixels by optimizing the mean variance at the spatial and feature levels. It enhances the texture and semantic features of pedestrians and fuses the features of different scales …

Design And Realization Of Integrated Energy System Dynamic Stability Simulation And Steady-State Simulation System, Guixiong He, Xiaoqiang Jia, Shufeng Dong, Yonglu Han, Yonghua Chen, Yiming Zheng

Journal of System Simulation

Abstract: Aiming for“carbon peak”and“carbon neutrality”, the energy sector is undergoing significant reform. To address energy flow and planning optimization in integrated energy systems, a comprehensive simulation platform is developed. This platform combines physical and digital simulations with real-world validation and is modular in design, It includes an integrated energy model library, energy flow optimization, modeling management, real-time simulation, and energy monitoring. The platform enhances system safety, stability, and economic efficiency, While also improving planning and energy management. The paper analyzes the platform′s functional and physical architecture, introduces key modules, establishes dynamic and steady-state model libraries, and optimizes energy flow using …

Research On Modeling Methods For Industrial Core Capability Architecture Based On The Dodaf Framework, Xiaoqiang Dou, Yan Liu, Zhilong Zhao, Chao Fu, Fulin Zhang, Shanshan Zou

Journal of System Simulation

Abstract: Against the backdrop of the industrial sector actively pursuing digital capability building, this paper describes the necessity and current status of architecture theory methods guiding industrial core capability construction. It proposes the conceptual connotation of industrial core capability architecture and four key modeling elements. Based on DoDAF, it conducts the overall design of industrial core capability architecture. By integrating systems engineering principles, it establishes a five-stage process model for capability-building activities, embedding critical elements such as capability/business/ application/data/technology architecture viewpoint, and explains data model design, and logical compositions of various viewpoints. By selecting a capability building project in a …

Leveraging Artificial Intelligence In Education To Drive Cross-Sector Innovation, Brent Terwilliger, John Faraca

Publications

As artificial intelligence (AI) reshapes educational practices, particularly in technical fields such as uncrewed systems, robotics, and aviation/ aerospace, its integration raises promise and complexity. This exploratory study features an investigation of the impact AI tools adoption has on instruction, curriculum support, and workforce preparation, with a focus on online learning environments. Drawing from pilot survey data across aviation and aerospace education stakeholders and hands-on evaluation of AI video production platforms, findings reveal diverse applications, perceived benefits, and critical concerns, including ethical, pedagogical, and institutional challenges. Additionally, the analysis explored how AI-enabled education intersects with broader industry and government innovation …

A Catalytic Pathway For The Formation Of Cyanobenzene In Nitrogen-Rich Environments And The Spectroscopy Of The Reactive Intermediates, Vincent J. Esposito, Silvia Alessandrini, David Dubois, Ryan Fortenberry

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

The catalytic reaction of isocyanobenzene (C₆H₅NC) with NCN⁻ produces cyanobenzene (C₆H₅NC) through various highly stable reactive intermediate species. Nitrogen-rich environments such as Titan’s atmosphere serve as favorable locations to study reaction pathways involving nitrogenated species contributing to organic growth. Formation pathways of cyanobenzene have been characterized, but none with the contribution of anions or phenyl groups. In regions with a high abundance of nitrogen anions, such as Titan’s atmosphere, reactions with species such as NCN⁻ may play a role in the formation of cyanobenzene. Highly accurate computational methods are used …

Investigating Potential Sugar-Related Uncertainties In A Proxy For Ancient Co2, Liam Cooper

Student Theses and Dissertations

The ε_p proxy for ancient pCO₂ can potentially estimate ancient pCO₂ as from the evolution of rubisco-based photosynthesis, using the difference in stable carbon isotope ratios (δ¹³C) between fixed and inorganic carbon, assuming this difference is proportional to pCO₂. This study aims to address uncertainty with the use of photosynthetic microbes in proxies for ancient pCO₂. While previous studies address uncertainties related to the δ¹³C of initial fixed photosynthate (e.g., growth rate), we aim to address the effects of downstream carbon allocation. Specifically, if a significant fraction of fixed …

Book Review Of, Participatory Engineering Of Algorithmic Socialtechnologies: An Extended Book Review Of David G. Robinson's Voices Inthe Code, Rajesh Venkatachalapathy

Complex Systems Faculty Publications and Presentations

David G. Robinson’s Voices in the Code, reviewed here, approaches the issue of governance and regulation of algorithmic social technologies with a case study orientation that offers a grounding in the details, illuminating the fundamentally sociological and processual nature of modern governance issues that are mostly missed or left implicit in academic, regulatory, and legislative discussions. This important book urges us to design adaptive, malleable, and evolvable participatory organizational structures instead. Accepting the author’s invitation to carry the torch forward, this review builds on and extends the book’s arguments by presenting broad and transferable insights on regulation and governance …

Historical Perspectives In Volatility Forecasting Methods With Machine Learning, Zhiang Qiu, Clemens Kownatzki, Fabien Scalzo, Eun Sang Cha

All Faculty Open Access Publications

Volatility forecasting for financial institutions plays a pivotal role across a wide range of domains, such as risk management, option pricing, and market making. For instance, banks can incorporate volatility forecasts into stress testing frameworks to ensure they are holding sufficient capital during extreme market conditions. However, volatility forecasting is challenging because volatility can only be estimated, and different factors influence volatility, ranging from macroeconomic indicators to investor sentiments. While recent works show promising advances in machine learning and artificial intelligence for volatility forecasting, a comprehensive assessment of current statistical and learning-based methods is lacking. Thus, this paper aims to …

Survey On Large Language Agent Technologies For Intelligent Game Theoretic Decision-Making, Xueqiang Gu, Junren Luo, Yanzhong Zhou, Wanpeng Zhang

Journal of System Simulation

Abstract: The development of artificial intelligence technology has greatly promoted the transformation of the solving paradigm of intelligent game decision problems. From optimal solution, equilibrium solution to adaptive variable solution, how to build an intelligent game adaptive decision agent based on generative large model is full of challenges. The force distribution and multi-entity coordination in the game strong confrontation environment are the core issues in the study of troop deployment and operational coordination. Based on the methods of strategy reinforcement learning, strategy game tree search and strategy preference voting based on skill, ranking and preference meta-game model construction, a large …

Method For Dynamic Coalition Formation Of Wargame Agent For Force Cooperation, Changhua Yao, Shanning Bi, Rufei Ma, Xiaohan Yu, Jiaqiang Li, Jinli Chen

Journal of System Simulation

Abstract: Regarding the issue of cooperative task alliance formation and adjustment in multi-agent dynamic confrontation scenarios at the tactical level, this method comprehensively considers factors such as target value, task allocation, and operator characteristics, as well as the benefits and costs of executing different types of tasks. we propose a targeted force coordination adjustment for dynamic task alliance formation based on behavioral constraints. The “MiaoSuan-Wise Winning Instant Strategy Human-Computer Confrontation Platform” of Chinese Academy of Sciences (CAS) is used as an experimental platform to conduct confrontation experiments. The experiment demonstrates that the proposed method improves the dynamic coordination ability of …

Modeling And Simulation Of Intelligent Underwater Acoustic Countermeasure Based On The Matrix Game, Huijin Zhao, Yu Chen

Journal of System Simulation

Abstract: Due to the great threat of torpedo against surface warships, an efficient hydroacoustic countermeasure system must output real-time strategies to accommodate varied antagonizing scenarios. Aiming at the decision-making problem in the anti-torpedo hydroacoustic countermeasure cases, an intelligent adversarial strategy is proposed based on the game theory. By discretizing the strategy space of both sides, a matrix game model is established where the payoff is characterised by the capture probability of attacking torpedo. An improved simplex algorithm is then developed to get the mixedstrategy Nash equilibrium of the game model, which can be used to obtain preferred avoidance strategies to …

Similarity Metrics, Metrics, And Conditionally Negative Definite Functions, Daniel Alpay, Liora Mayats-Alpay

Mathematics, Physics, and Computer Science Faculty Articles and Research

We give an example of a similarity metric which is not positive definite, and present a general theorem which provides a large family of similarity metrics which are positive definite.

Why Commencement Will Be The One Ritual Ai Will Never Replace, Essraa Nawar

Library Articles and Research

"We are entering an era of unimaginable change.

Artificial Intelligence is transforming how we work, learn, create, and think. It’s reshaping higher education—and pushing many to ask: Is college still worth it? Are degrees still necessary?

Those questions are real. And I welcome them.

But I also know this: no machine can replace the moment a family claps through tears when their loved one walks the stage."

Hierarchical Optimal Scheduling Of Integrated Energy System With Electric Vehicles Based On Empc, Miaomiao Ma, Zijuan Long, Zhiwei Ren, Yongqiang Cheng

Journal of System Simulation

Abstract: A hierarchical real-time optimization (HRTO) based on economic model predictive control is designed to address the issues of randomness and uncertainty of renewable energy and demand-side in integrated energy systems (IES) with electric vehicles. The optimization problem of the entire system is divided into three sub-problems: day-ahead rolling optimization, real-time rolling optimization, and tracking control. The day-ahead optimization strategy based on economic model predictive control is constructed to ensure that the operational units can meet users' demands. The optimal steady-state operating points of the entire IES are obtained through the real-time optimization layer. The tracking model predictive controller is …

Optimal Scheduling Of Virtual Power Plant With Coupled Operation Of Ccs-P2g Considering Wind And Photovoltaic Uncertainty, Xurong Jin, Jiang Yin, Guohua Yang, Wei Li, Guobin Wang, Lele Wang, Na Yang, Xuenian Zhou

Journal of System Simulation

Abstract: In order to solve the problem that the uncertainty of wind power and photovoltaic power generation output easily affects the scheduling of virtual power plant, a new optimal scheduling model of virtual power plant is proposed based on information gap decision theory (IGDT) . In order to reduce the carbon emission of the system, carbon capture and storage (CCS) is installed on the combined heat and power units; in order to improve the utilization rate of renewable energy, the power to gas (P2G) device is introduced into the system, and the operation mode of CCS-P2G coupling is proposed; based …

A Quadrotor Trajectory Tracking Control Method Based On Deep Reinforcement Learning, Guohua Wu, Jiaheng Zeng, Dezhi Wang, Long Zheng, Wei Zou

Journal of System Simulation

Abstract: Traditional quadrotor controllers, constrained by fixed model equation structures, encounter challenges in addressing control errors stemming from variations in parameters and environmental disturbances. This paper proposes a deep reinforcement learning solution for the quadrotor trajectory following control problem. We present the PPO-SAG algorithm incorporated into the PPO framework, utilizing adaptive mechanisms and PID expert knowledge to enhance training convergence and stability. Target functions incorporating distance constraint penalties and entropy policies are designed in alignment with the characteristics of the given problem. We also devise innovative disturbance-adaptive structures and trajectory feature selection mechanisms to augment control error information and extract …

Improved Hybrid Optimization Algorithm For Multi-Objective Ipps Problem, Wenbin Gu, Jiexia Qing, Jie Fang, Siqi Liu

Journal of System Simulation

Abstract: For the problem of multi-objective integrated process planning and scheduling (MOIPPS), an improved hybrid optimization algorithm considering global and local optimum is proposed to optimize two objectives about minimum makespan and energy consumption. A multi-objective problem model and solution framework are established by analyzing the difference and connection between process planning and scheduling in integrated system. A hybrid optimization algorithm is proposed for the two-stage integration problem. In the process planning stage, global search algorithm is employed to provide a variety of process schemes for the integrated system and to ensure the global search performance of the integrated algorithm. …

Optimization Of Cargo Location Allocation In Four-Way Shuttle Warehousing System Based On Two-Stage Hybrid Algorithm, Zisong Wu, Daofang Chang, Yuchun Gai

Journal of System Simulation

Abstract: To address issues such as the dense distribution of storage locations and the potential congestion of shuttle vehicles in the four-way shuttle dense storage system, a grid-based approach to the storage location distribution is developed. A location allocation model is then constructed with the goals of ensuring shelf stability, improving warehousing efficiency, and balancing equipment utilization. A twostage hybrid algorithm is designed for the model. In the first stage, the local search strategy of nondominant sequencing genetic algorithm(NSGA-II) is enhanced by incorporating the hill climbing algorithm to address a set of Pareto front sets. In the second stage, the …

Research On Decision-Making Of Autonomous Driving In Highway Environment Based On Knowledge And Large Language Model, Xiang Wang, Guozhen Tan

Journal of System Simulation

Abstract: Aiming at the lack of continuous learning and interpretability of current autonomous driving system, a decision model with cognition, generalization and learning ability is proposed. The model utilizes large language model (LLM) and attention mechanisms to understand and explain driving scenes. the system can accumulate and learn from driving experiences, continuously improving its decisionmaking ability. In a simulation environment, the closed-loop test decision model is applied in high-speed scenarios.The simulation results show that the success rate of the knowledge-driven model is 7% and 4% higher than those of the rule-based and data-driven methods. Additionally, the model exhibits generalization and …

Robot Path Planning Based On Ant Colony Algorithm With Dual Heuristic Information, Xiaohui Zhou, Yanqiang Li, Yong Wang, Decai Zhao, Xiaoyao Yang

Journal of System Simulation

Abstract: The traditional ant colony algorithm is characterized by a slow convergence speed, numerous turning points, and a tendency to fall into local minima. These characteristics make the algorithm less effective for path planning research in mobile robotics. Therefore, this paper proposes an improved ant colony algorithm and applies it to global path planning for robots. The A* algorithm is used to quickly plan a path and increase the initial pheromone of that path, so that the improved algorithm is guided by the global path during the local search, preventing excessive ants from entering dead ends, and reducing the randomness …

A Simulating Framework Construction Method About New Distributed Confrontation, Zhipeng Liu, Yanyang Gu, Baojie Hu, Fangjun He, Zhipeng Fan

Journal of System Simulation

Abstract: The new distributed confrontation in future emphasizes systematic combat and flexible use of power in the resistance environment. To study and analyze the potential threats of such new forms of distributed confrontation, this paper proposes a system confrontation strategy focused on decisionmaking confrontation from the perspective of network and electromagnetic space. In addition, a highly flexible and saleable behavior model adversarial framework is proposed. By parameterizing the network and electrical countermeasure strategy, an adversarial model based on typical airspace scenarios is designed, and the confrontation effectiveness of traditional multifunctional platforms and distributed units is quantitatively compared and analyzed. The …

Research On A Credibility Information Management Method Of Simulation Modeling, Qiming Gu, Jiazhi Chen, Guoyan Cao, Chenchu Zhou, Dengxiu Yu, Haifeng Hu

Journal of System Simulation

Abstract: A proposed method for managing credibility information in simulation modeling draws insights from the NASA-STD-7009 standard for modeling and simulation. From the perspective of credibility information recording, definition, and assessment, this method aims to address the core issue of whether the credibility requirements are met in simulation modeling research. A simulation system credibility information extraction tool is designed to extract three types of information including modeling credibility information, data credibility information, and development process credibility information, enabling recording, definition, and traceability of credibility information in simulation models. Taking a servo system credibility evaluation as an example, a simulation system …

Histone Methyltransferase Ash1l Primes Metastases And Metabolic Reprogramming Of Macrophages In The Bone Niche, Chenling Meng, Kevin Lin, Wei Shi, Hongqi Teng, Xinhai Wan, Anna Debruine, Yin Wang, Xin Liang, Javier Leo, Feiyu Chen, Qianlin Gu, Jie Zhang, Vivien Van, Kiersten L Maldonado, Boyi Gan, Li Ma, Yue Lu, Di Zhao

Faculty, Staff and Student Publications

Bone metastasis is a major cause of cancer death; however, the epigenetic determinants driving this process remain elusive. Here, we report that histone methyltransferase ASH1L is genetically amplified and is required for bone metastasis in men with prostate cancer. ASH1L rewires histone methylations and cooperates with HIF-1α to induce pro-metastatic transcriptome in invading cancer cells, resulting in monocyte differentiation into lipid-associated macrophage (LA-TAM) and enhancing their pro-tumoral phenotype in the metastatic bone niche. We identified IGF-2 as a direct target of ASH1L/HIF-1α and mediates LA-TAMs' differentiation and phenotypic changes by reprogramming oxidative phosphorylation. Pharmacologic inhibition of the ASH1L-HIF-1α-macrophages axis elicits …