Physical Sciences and Mathematics Commons^™

Diffusion Mechanisms Of Power-Law Grouts In Water-Rich Sand Layers During Permeation Grouting, Xie Bao, Cheng Hua, Wang Xuesong, Li Mingjing, Liu Xiangyang, Han Xueyu

Coal Geology & Exploration

Objective This study aims to clarify the spherical diffusion patterns of power-law grouts in water-rich sand layers during permeation grouting and their influential factors. To this end, permeation grouting experiments were conducted to gain insights into the quantitative impacts of varying grouting parameters on grout diffusion.Methods Using model experiments on spherical diffusion during permeation grouting, this study analyzed the macroscopic diffusion morphologies and microscopic infilling effects of grouts, as well as the trends of permeation and soil pressures during grouting. Then, based on the spherical diffusion equations for permeation grouting that consider multi-effect coupling, this study analyzed the factors …

A Method For Efficient Virtual-Physical Synchronization Of The Digital Twin System Of An Excavation-Supporting Robot Cluster Targeting Coal Pillars Between Mining Faces, Mao Qinghua, Sima Junlei, Ma Hongwei, Wang Chuanwei, Chen Yanzhang, Guo Wenjin, Cui Wenda, Cheng Jiashuai

Coal Geology & Exploration

Objective Virtual models for excavation-supporting robot clusters targeting coal pillars between mining faces encounter challenges like a large data size and anomalies in data transmission, which lead to poor virtual-physical synchronization. This study proposed a method for efficient virtual-physical synchronization of the digital twin (DT) system of an excavation-supporting robot cluster using 3D model lightweighting and a trajectory prediction and correction model. Methods Fit-controlling vertices were defined, and their collapse cost factor was introduced to improve the quadratic error metric (QEM) algorithm and to constrain the lightweighting process of the 3D model of an assembly while maintaining fits between components. …

An Improved Mp-Nmo Correction Method Based On Multiparameter Fitting And Its Application, Yang Xiaohui, Yu Pengfei, Zhang Jiawei

Coal Geology & Exploration

Objective and Methods Normal moveout (NMO) correction is a core step in seismic data processing. However, the conventional NMO correction method tends to cause wavelet stretching when processing wide-angle or large-offset seismic data, leading to degraded stacking quality and distorted amplitude variation with offset (AVO) attributes. Although the matching pursuit (MP)-NMO correction method can mitigate the stretching effect, it will cause lateral discontinuity due to overlapping seismic events. Therefore, this study developed an improved MP-NMO correction method based on multiparameter fitting. Specifically, during MP decomposition, cubic polynomial fitting was applied to the amplitude, frequencies, and phases of wavelets from the …

Color Tests For The Presumptive Identification Of A Range Of Benzodiazepines, Regan Mulvin

Honors Projects

Color tests are presumptive chemical tests that determine the class of drug in both laboratory and field settings. Despite the rising popularity of benzodiazepines and the usefulness of color tests, there is no widely accepted color test for identifying them. This study tested six different color tests against five benzodiazepines, including diazepam, clonazepam, lorazepam, alprazolam, and flualprazolam, to identify which of the tests would work most generally across all benzodiazepines. Of the six tests, the McKibben test, the Janovsky test, and the Zimmerman test all showed potential usefulness as a presumptive color test. More studies should be done on a …

Discovery Of Drug Transporter Inhibitors Tied To Long Noncoding Rna In Resistant Cancer Cells; A Computational Model -In Silico- Study, Mohanad Diab, Amel Hamdi, Feras Al-Obeidat, Wael Hafez, Ivan Cherrez-Ojeda, Muneir Gador, Gowhar Rashid, Sana F. Elkhazin, Mahmad Anwar Ibrahim, Tarek Farag Ismail, Samar Sami Alkafaas

All Works

Chemotherapeutic resistance is a major obstacle to chemotherapeutic failure. Cancer cell resistance involves several mechanisms, including epithelial-to-mesenchymal transition (EMT), signaling pathway bypass, drug efflux activation, and impairment of drug entry. P-glycoproteins (P-gp) are an efflux transporter that pumps chemotherapeutic drugs out of cancer cells, resulting in chemotherapeutic resistance. Several types of long noncoding RNA (lncRNAs) have been identified in resistant cancer cells, including ODRUL, MALAT1, and ANRIL. The high expression level of ODRUL is related to the induction of ATP-binding cassette (ABC) gene expression, resulting in the emergence of doxorubicin resistance in osteosarcoma. lncRNAs are observed to be regulators of …

Detection And Mitigation Of Out-Of-Band Channel Wormhole Attack In Wireless Network Using Propagation Delay, Harry May

Doctoral Dissertations

Wireless networks, susceptible to a range of attacks due to their simplicity and ease of evasion, face a significant threat from control data attacks, notably the elusive wormhole attack. Detecting and mitigating such attacks poses challenges, particularly in the absence of a digital signature. This dissertation introduces an innovative approach that utilizes the propagation delay associated with malicious nodes’ timing characteristics for detection, employing the Ad-hoc On-Demand Distance Vector (AODV) algorithm as its foundation. The inherent propagation delay in the AODV protocol is calculated for each node link along the entire communication path, offering a distinctive timing method that provides …

Dsa-Api: Data Standardization Automation Using Ai-Powered Apis, Andrew Asher Turner

Master's Theses

The common factor with current implementations of Artificial Intelligence (AI) is data. Companies are constantly looking for new ways to analyze data, but it comes in various formats: Text, Comma Separated Value (CVE), JavaScript Object Notation (JSON), Extensible Markup Language (XML), and Excel. How can AI be adapted to standardize formats for data analysis, integration, and digestion efficiently? Published research acknowledged that Machine Learning (ML) and AI can provide an automated method to speed up this process and limit the human decision-making error. With the advancement in AI, Application Programming Interfaces (APIs) prompt the idea that they can take in …

Who Should Take Responsibility For Artificial Intelligence Actions And Outcomes? Perception Of Auditors As Users Of Ai Systems, Hanh Hoang Le

Doctoral Dissertations

As artificial intelligence (AI) systems become increasingly embedded in auditing processes, questions arise regarding how professional auditors perceive and allocate responsibility for AI-assisted decisions. This study investigates the effects of AI explainability and auditors’ perceived autonomy on perceived responsibility in the context of audit decision-making. Drawing on theories of moral responsibility and professional judgment, the study employs a 2x2 experimental design using hypothetical audit scenarios to manipulate levels of AI explainability and auditors’ autonomy. Hierarchical regression analysis reveals that perceived autonomy statistically significantly increases auditors’ perception of responsibility for AI-assisted decisionmaking, whereas AI explainability is not a significant predictor. Additionally, …

Nuclear Magnetic Resonance Dynamics Of Pyrazole-Litfsi Eutectic Solvents As Promising Electrolytes, Emilia Pelegano-Titmuss, Giselle De Araujo Lima E Souza, Muhammad Zulqarnain, Ramez Elgammal, Thomas Zawodzinski, Steven Greenbaum

Undergraduate Research

Deep Eutectic Solvents (DESs) have emerged as promising candidates to replace conventional organic solvents in various technological applications due to their low vapor pressure, non-flammability, and ease of preparation at low costs. In particular, Type IV DESs, which are composed of metal salts and hydrogen bond donors, are possible replacements for lithium-ion battery electrolytes due to their potential of having high lithium transference numbers. In this study, we investigated solvents of Pyrazole and LiTFSI at varying molar ratios using Fast Field Cycling (FFC) NMR Relaxometry. Notably, the 1:2 LiTFSI: Pyrazole sample shows distinct behavior, exhibiting enhanced relaxation rates for ^{1 …}

Characterization Of Sars-Cov-2 Replication And Transcription Complexes Via Structural And Evolutionary Approaches, Amelie Ghirardo, Ben Shabatian, Avishai Aghelian, Kyle Tau, Eleonora Gianti

Undergraduate Research

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused around 700M cases and over 7M COVID-19-related deaths recorded worldwide (World Health Organization, March 2025). Aiming to effectively combat this and other disease-causing Coronaviruses (CoV), unprecedented research efforts led to the development of new vaccines and antiviral therapies. Due to emergence of variants of concern (VOCs) with increased transmissibility, immune evasion from vaccination, and potential to resist the available treatments, SARS-CoV-2 continues to represent a major threat to global health. Hence, there is a pressing need to discover new antivirals with broad-spectrum efficacy against multiple SARS-CoV-2 variants and related CoVs. This project …

Design And Optimization Of Low-Loss, High-Gain Metamaterial-Based Log-Periodic Dipole Array Antenna For Full Ka-Band Coverage, Mohamed El Moniar, Ahmed Abd El Hady, Yasser Ismail, Nihal Areed

Turkish Journal of Electrical Engineering and Computer Sciences

This work describes a microstrip log-periodic dipole array (MLPDA) antenna that uses metamaterials and operates across the whole Ka-band. The suggested MLPDA antenna layout provides a wide bandwidth with fewer dipole elements than traditional MLPDA antennas while maintaining the same resonance frequencies. To reduce size while covering a wide operational spectrum, the antenna design includes bending dipoles as radiating elements, as well as an incomplete ground plane. Furthermore, the proposed MLPDA antenna’s energy loss has been reduced while boosting its signal strength (gain) by inserting a metamaterial-based structure in front of it at a certain distance and on the same …

Factors Influencing Student Motivations And Experiences In Stem Course Office Hours, Gabriella R. Dauber, Jeremy L. Hsu

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Office hours are a part of nearly all science, technology, engineering, and mathematics (STEM) courses, with many academic and affective benefits for students who attend. However, despite their ubiquity, there has only been limited past work examining the sources of knowledge students draw from to shape their perceptions of office hours, as well as the factors that influence students' experiences in STEM course office hours. Here, we conducted semistructured interviews with 20 students enrolled in an introductory STEM course to investigate what motivates students to attend STEM course office hours, the factors that shape their experiences in office hours, and …

Fired And Fractured: An Analysis Of Broken Ceramics, Evan Mcguire

Honors Projects

How does the construction of a ceramic object affect how it breaks? How does the force applied affect this break? These questions are based on my first-hand observations of the multitude of ceramic fragments found in different states of decay at archaeological sites. To answer these questions, I created samples that imitate ancient ceramics and then broke them in different ways. I then analyzed the fracture surfaces and looked for evidence of weak points in the objects. Pieces that were hit by a blunt force, such as a hammer, had radial fractures that formed along paths that had clusters of …

Draft Final 2024 Residential Metals Abatement Program (Rmap): Walkerville Park (Walkerville Drive & Ryan Road) Soil Remedial Action Construction Completion Report, Pioneer Technical Services, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Re: Approval Letter For The Butte Priority Soils Operable Unit (Bpsou) Final Multi-Pathway Residential Metals Abatement Program (Rmap) Plan (Dated March 27, 2025), Molly Roby

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Draft Final 2025 Residential Metals Abatement Program (Rmap) Rock Creek Cattle Company Borrow Submittal #1, Pioneer Technical Services, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Helmholtz Cage: Software Development And Implementation For Cubesat Testing, Gustavo A. Cotom Lopez

University Honors Theses

This paper details the successful development and deployment of a Helmholtz cage system, designed to produce precisely controlled magnetic fields for testing and calibration purposes. The core focus was on creating a robust, modular software architecture enabling independent current modulation on each axis, comprehensive serial communication between multiple microcontrollers, and real-time data acquisition from the MR3 magnetometer. All software components, including the serial communication drivers, control algorithms, command line interface, and calibration routines, were developed from the ground up. The system was fully operational upon completion: all hardware components functioned as intended, serial communication with each subsystem was reliable, and …

Blockchain-Enabled Master Data Management, Shakhawat Hossain

Theses and Dissertations

Master Data Management (MDM) is essential for maintaining data quality, accuracy, consistency, and governance within organizations. However, traditional centralized MDM systems continue to face challenges related to data integrity, security, and scalability. This research presents a blockchain-enabled MDM framework designed to overcome these limitations by leveraging blockchain’s decentralized, immutable, and secure architecture. The study aims to identify and address the shortcomings of conventional MDM practices, examine the applicability of blockchain technology in enhancing these systems, and develop a functional prototype to validate the proposed model. The framework incorporates decentralized review mechanisms that improve auditability and ensure trusted data verification by …

Conditional Quantization For Some Discrete Distributions, Edgar A. Gonzalez, Mrinal Kanti Roychowdhury, David A. Salinas, Vishal Veeramachaneni

School of Mathematical & Statistical Sciences Faculty Publications

Quantization for a Borel probability measure refers to the idea of estimating a given probability by a discrete probability with support containing a finite number of elements. If in the quantization some of the elements in the finite support are preselected, then the quantization is called a conditional quantization. In this paper, we have determined the conditional quantization, first for two different finite discrete distributions with a same conditional set, and for a finite discrete distribution with two different conditional sets. Next, we have determined the conditional and unconditional quantization for an infinite discrete distribution with support {12𝑛:𝑛∈ℕ}. We have …

Hotlangbench, A Tiny Benchmark Suite For Higher-Order Statically Typed Languages, Konstantin Laufer

Computer Science: Faculty Publications and Other Works

This work in progress aims to compare various HOT (higher-order and statically typed, a term coined by Phil Wadler) through reproducible course-grained, wall-time benchmarks. Our overall goals include simplicity, agility, and reproducibility.

There is currently only one benchmark, but it brings out substantial performance differences among the various languages and platforms. It uses function composition and other higher-order constructs to build a pipeline of transformations, along with a brute-force iteration that is computationally expensive for input files specifying large ranges as function domains. We currently include versions in Modern C++, C#, Go, Haskell, Kotlin, Modern (stream-based) Java (24), OCaml, Scala …

All Graphs Of Order N With Distinguishing Number N−1 Or N − 2, Andi Pujo Rahadi, Edy Tri Baskoro, Suhadi Wido Saputro

Theory & Applications of Graphs

Let G be a simple connected graph. The distinguishing number of G, denoted by D(G), is the least integer d such that G has a vertex d-labeling preserved only by the trivial automorphism. In this paper, we characterize all graphs of order n with distinguishing number n − 1, or n − 2.

Transformer Decoder-Enhanced Swin Unetr For Multi-Organ Semantic Segmentation On Openkbp: Improving Radiotherapy Planning Accuracy, Zainab Adnan Jwad, Israa Hadi Ali

Karbala International Journal of Modern Science

Accurate segmentation of organs-at-risk (OARs) in head and neck CT scans is crucial for radiotherapy planning. The CNN-based decoder limitation of Swin UNETR hinders its capacity to process meaningful information from multiple organ positions essential for accurate medical segmentation. The proposed Transformer Decoder-enhanced Swin UNETR model targets the OpenKBP dataset multi-organ segmentation through its dedicated design for this purpose. The model utilizes transformers along with cross-attention approaches in its decoder to improve segmentation mask outputs through analysis of extensive global information. The model gets additional feature representation power through the addition of squeeze-and-excitation (SE) blocks linked with spatial attention mechanisms …

Computational Approach: 3d-Qsar, Molecular Docking, Molecular Dynamics Simulation Investigations, Drug- Like-Ness, And Dft Score Evaluation Of A Potential Novel And Retrosynthesis Of Some Tr-H Derivatives As Streptococcus Pneumoniae Drug., Belaidi Mustapha, Tchouar Noureddine, Djelilate Mohammed, Saleh Bufarwa, Dalal K. Thbayh

Karbala International Journal of Modern Science

Streptococcus pneumoniae is the main source of hospital-acquired pneumonia and meningococcal pneumonia in children, adults, and the elderly, especially the immunocompromised. Recently, it has attracted the attention of many research studies around the world as a potential target for remediation. TR-H are considered SP antibacterial agents, as they can inhibit. To describe their mode of action and to identify new antibacterial drugs against Streptococcus pneumoniae exhibiting the TR-H scaffold, the present work included 3D-QSAR, in- silico pharmacokinetic evaluation and molecular simulation modelling of TR-H. Using an atom-based method for quantitative structure-activity relationship (QSAR) study, a comprehensive 3D-QSAR model …

Dynamate: Leveraging Ai-Agents For Customized Research Workflows, Orlando A. Mendible-Barreto, Misael Díaz-Maldonado, Fernando J. Carmona Esteva, J. Emmanuel Torres, Ubaldo M. Córdova-Figueroa, Yamil J. Colón

Computer and Data Science Faculty Publications

No abstract provided.

Conformational Change In A Four-Tetrad Dna G-Quadruplex Upon Intercalation Of A Small-Molecule Ligand Pydh2, Kailey N. Martin, Gwendolyn Lam , '24, O. Reznichenko, K. E. Brunner, M. J. Zdilla, Sawyer E. Mccarthy, Liliya A. Yatsunyk

Chemistry & Biochemistry Faculty Works

G-quadruplexes (G4s) are non-canonical DNA structures implicated in a number of biological processes. Small-molecule ligands can alter stability and folding of G4s, which can potentially be exploited for therapeutic purposes. In this work, we investigate the interaction of telomeric DNA fragment from Tetrahymena thermophila (TET25, 5′-G(TTGGGG)₄-3′) with a G4 ligand PyDH2 belonging to the bisquinolinium family. When alone, TET25 adopts a mixture of three conformations, with the most abundant being a four-tetrad hybrid G4. In the presence of PyDH2, surprisingly, TET25 folds into an antiparallel chair G4, with PyDH2 intercalated between G-tetrads 2 and 3, according to our crystal structure. …

Selected Artificial Intelligence Provisions In U.S. Fiscal Year 2025 National Defense Authorization Act, Bert Chapman

Libraries Faculty and Staff Presentations

The 2025 Fiscal Year National Defense Authorization Act contains multiple provisions relating to artificial intelligence (AI). These congressionally mandated provisions direct various sections of the Department of Defense (DOD) and individual U.S. armed service branches to execute congressional intent for AI policymaking. Examples of such intent include identifying and planning DOD's AI workforce, demonstrating AI biotechnology applications for national security, improving the human usability of AI systems, and establishing an AI security center. This presentation will note that reports on these initiatives must be prepared for relevant congressional oversight committees, and, in many cases, are in many cases, publicly released …

Integrative Computational Modeling Of Distinct Binding Mechanisms For Broadly Neutralizing Antibodies Targeting Sars-Cov-2 Spike Omicron Variants: Balance Of Evolutionary And Dynamic Adaptability In Shaping Molecular Determinants Of Immune Escape, Mohammed Alshahrani, Vedant Parikh, Brandon Foley, Gennady M. Verkhivker

Mathematics, Physics, and Computer Science Faculty Articles and Research

In this study, we conducted a comprehensive analysis of the interactions between the receptor-binding domain (RBD) of the SARS-CoV-2 spike protein and four neutralizing antibodies—S309, S304, CYFN1006, and VIR-7229. Using integrative computational modeling that combined all-atom molecular dynamics (MD) simulations, mutational scanning, and MM-GBSA binding free energy calculations, we elucidated the structural, energetic, and dynamic determinants of antibody binding. Our findings reveal distinct dynamic binding mechanisms and evolutionary adaptation driving the broad neutralization effect of these antibodies. We show that S309 targets conserved residues near the ACE2 interface, leveraging synergistic van der Waals and electrostatic interactions, while S304 focuses on …

Re: Comment Letter For Draft Final Butte Priority Soils Operable Unit (Bpsou) Unreclaimed Sites Ur-05 Remedial Action Work Plan (Rawp) (Dated March 14, 2025), Molly Roby

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

2025 May 22 - Tennessee Weekly Drought Summary, Tennessee Climate Office, East Tennessee State University

Tennessee Climate Office Weekly Drought Summaries

No abstract provided.

The Future Of The Us Marine Seafloor And Subseafloor Sampling Capabilities, Future 2024 Pi-Team, Olga Libman‐Roshal

Department of Earth and Environmental Studies Faculty Scholarship and Creative Works

Recent changes in US oceanographic assets are impacting scientists' ability to access seafloor and sub-seafloor materials and thus constraining progress on science critical for societal needs. Here we identify national infrastructure needs to address critical science questions. This commentary reports on community-driven discussions that took place during the 3-day FUTURE of US Seafloor Sampling Capabilities 2024 Workshop, which used an “all-hands-on-deck” approach to assess seafloor and sub-seafloor sampling requirements of a broad range of scientific objectives, focusing on capabilities that could be supported through the US Academic Research Fleet (US-ARF) now or in the near future. Cross-cutting issues identified …