Physical Sciences and Mathematics Commons^™

Substituted Piperidines As (Alpha4)3(Beta2)2 Nicotinic Acetylcholine Receptor Positive Allosteric Modulators: In Vitro Pharmacology, Nataly Sanchez, Josue Gaona, Wilder Felix, Nathalia Menegasso, Brisa Cea, Ganesh Thakur, Ayman K. Hamouda

School of Medicine Student Publications and Presentations

Nicotinic acetylcholine receptors (nAChRs) play a crucial role in the pathogenesis of neurodegenerative diseases such as Parkinsonʼs disease (PD). In PD, degeneration of dopaminergic and cholinergic neurons impairs neurotransmitter release, leading to cognitive and motor dysfunction. Current treatments provide only symptomatic relief, highlighting the need for novel therapeutic strategies. The (α4)₃(β2)₂ subtype of nAChRs is expressed on affected neurons, making it a promising druggable target for enhancing neurotransmitter release and providing neuroprotection. To explore the therapeutic potential of positive allosteric modulators (PAMs) of (α4)₃(β2)₂ nAChRs, we evaluated chemical derivatives of CMPI [3-(2-chlorophenyl)-5-(5-methyl-1-(piperidin-4-yl)-1H-pyrazol-4-yl)isoxazole]. We used two-electrode voltage-clamp recordings from Xenopus laevis …

Be+ Assisted, Simultaneous Confinement Of More Than 15000 Antihydrogen Atoms, Tim Tharp

Physics Faculty Research and Publications

Antihydrogen, the bound state of a positron and an antiproton, is the only pure anti-atomic system ever studied. It is produced exclusively in the laboratory, as it has never been observed in nature. This unique system is of great interest for searching for tentative differences between matter and antimatter. Antihydrogen has been routinely trapped since 2010 and accumulated since 2017, enabling, for example, the first precision spectroscopic study of the anti-atom in 2018 and the first observation of the influence of gravity in 2023. Here we report an eight-fold increase in the trapping rate of antihydrogen, enabled by sympathetic cooling …

Multicomponent One-Dimensional Quantum Droplets Across The Mean-Field Stability Regime, I. A. Englezos, P. Schmelcher, S. I. Mistakidis

Physics Faculty Research & Creative Works

The Lee-Huang-Yang (LHY) energy correction at the edge of the mean-field stability regime is known to give rise to beyond mean-field structures in a wide variety of systems. In this work, we analytically derive the LHY energy for two-, three-and four-component one-dimensional bosonic short-range interacting mixtures across the mean-field stability regime. For varying intercomponent attraction in the two-component setting, quantitative deviations from the original LHY treatment emerge being imprinted in the droplet saturation density and width. On the other hand, for repulsive interactions an unseen early onset of phase-separation occurs for both homonuclear and heteronuclear mixtures. Closed LHY expressions for …

Harnessing Coherent-Wave Control For Sensing Applications, Pablo Jara, Arthur Goetschy, Hui Cao, Alexey Yamilov

Physics Faculty Research & Creative Works

Imaging techniques such as functional near-infrared spectroscopy and diffuse optical tomography (DOT) achieve deep, noninvasive sensing in turbid media; however, they are constrained by the photon budget, as most of the injected light is lost to scattering before reaching the detector. Wavefront shaping (WFS) can enhance signal strength via interference at specific locations within scattering media, enhancing light-matter interactions and potentially extending the penetration depth of these techniques. Interpretation of the resulting measurements relies on knowing the optical sensitivity - the relationship between changes in the detected signals and perturbations at a specific location inside the medium; however, conventional diffusion-based …

Active Galactic Nuclie In Diverse Galactic Environments, Divya A. Patel

College of Arts & Sciences Senior Theses

We examine how the presence of active galactic nuclei (AGN) correlates with location in large-scale cosmic structures using the Galaxy and Mass Assembly (GAMA) survey across the G09, G12, and G15 fields. Our sample contains 18,927, 9,273, and 1,148 galaxies {with} highly dense filaments, moderately dense tendrils, and highly underdense voids, respectively. AGN galaxies were identified using Baldwin-Phillips-Telverich (BPT) diagnostic diagrams based on [NII], [SII], and [OI]. We compare AGN fractions in filament, tendril, and void regions, and as a function of distance from the nearest filament centerline. Our results reveal a mild excess in filament compared to void, when …

Guided Modes Of Helical Waveguides, Jay Gopalakrishnan, Michael Neunteufel

Mathematics and Statistics Faculty Publications and Presentations

This paper studies guided transverse scalar modes propagating through helically coiled waveguides. Modeling the modes as solutions of the Helmholtz equation within the three-dimensional (3D) waveguide geometry, a propagation ansatz transforms the mode-finding problem into a 3D quadratic eigenproblem. Through an untwisting map, the problem is shown to be equivalent to a 3D quadratic eigenproblem on a straightened configuration. Next, exploiting the constant torsion and curvature of the Frenet frame of a circular helix, the 3D eigenproblem is further reduced to a two-dimensional (2D) eigenproblem on the waveguide cross section. All three eigenproblems are numerically treated. As expected, significant computational …

Living Shoreline Prioritization And Hydrodynamic Habitat Suitability Models For Restoration In The Indian River Lagoon And Lake Worth Lagoon, Florida, Kelly M. Kibler, Melinda J. Donnelly, Vincent Encomio, Madison Giuntoli, Manisha Thenuwara, Brice Bennett, Laura Andrade Barron, Mariam Sonbol, Wynter Raine Seppala, Namritha Ramakrishnan, Jennifer Jordan Báez, Beth Orlando, Irene Arpayoglou, Melissa Meisenburg

Indian River Lagoon Shorelines

The spatial dataset: UCF_shorelinemodel_IRL_LWL.shp, was created with support from the Indian River Lagoon National Estuaries Program and Florida Sea Grant. These projects cumulatively led to creation of a living shoreline restoration prioritization model and hydrodynamic habitat suitability models for 1,550 km (963 miles) of estuarine shorelines in Indian River Lagoon and Lake Worth Lagoon.

The dataset presented herein includes:

1. shoreline data from >15,000 transects collected in the field,
2. shoreline wave climate data created through hydrodynamic modeling and frequency analysis of historic data,
3. categorization of potential risk for shoreline boat wake impact,
4. persistence of seagrass within 210 m of the shoreline, …

‘Earth System Engineers’ And The Cumulative Impact Of Organisms In Deep Time, S. A. F. Darroch, M. M. Casey, A. T. Cribb, A. E. Bates, M. E. Clapham, D. L. Contreras, M. Craffey, I. A. P. Duijnstee, W. Gearty, N. J. Gotelli, M. J. Hamilton, R. F. Hayes, P. M. Hull, D. E. Ibarra, V. A. Korasidis, J. Lee, C. V. Looy, T. R. Lyson, B. Muddiman, P. D. Roopnarine, A. B. Shupinski, F. A. Smith, A. L. Stigall, C. P. Tomé, K. A. Turk, A. Villaseñor, P. J. Wagner, Steve C. Wang

Mathematics & Statistics Faculty Works

Understanding the role of humans as ‘ecosystem engineers’ requires a deep-time perspective rooted in evolutionary history and the fossil record. However, no conceptual framework exists for studying the rise of ecosystem engineering in deep time, requiring us to consider effects that fall outside the scope of traditional definitions. Here, we present a new framework applicable to both modern and ancient engineering-type effects. We propose a new term – ‘Earth system engineering’ – to describe biological processes that alter the structure and function of planetary spheres, and which combines core tenets of ecosystem engineering, niche construction, and legacy effects. We illustrate …

The Problem Of Identification Of Linear Stationary Objects With Distributed Parameters By Their Experimental Transient Characteristics, Miraziz Vorisovich Sagatov

Chemical Technology, Control and Management

A wide class of control system elements can be described with reasonable accuracy by the concept of a linear stationary dynamic object. Several mathematical descriptions of such an object are known. The traditional mathematical model is a high-order ordinary linear differential equation. In the Laplace image space, this corresponds to a fractional-rational transfer function. The latter can be decomposed into elementary fractions. Then, using the convolution theorem and tables of elementary Laplace transform functions, one can access the originals. It is crucial to ensure precise alignment of the parameters of the mathematical model of the object used in the corrector …

Spatio-Temporal Gcn With Softmax Classifier For Skeleton-Based Human Action Recognition, Kabul Khudaybergenov, Avazjon Marakhimov, Zahriddin Muminov

Chemical Technology, Control and Management

Skeleton-based human action recognition is an important research area with many practical applications. Most existing methods rely on single representations of skeletal sequences, which cannot totally obtain all the complex features of human movements. This paper presents LFHAR (Latent Features for Human Action Recognition), a new framework that uses multiple spatio-temporal latent representations to improve the extraction of action features. Our method captures how skeletal poses change over time and combines motion information from both individual joints and connected body parts. The proposed approach applies graph-based processing to each skeleton frame in a sequence, then arranges the resulting graph features …

Catch Me If You Can: Microplastics Hidden In Plain Sight, Karin Mattsson, Pere Masque, Thomas Maes, Marc Metian

Research outputs 2022 to 2026

Microplastic (MP) pollution is widely recognised as a pressing environmental issue, yet certain major sources remain under-addressed. This paper focuses on three significant but often overlooked contributors: paint particles, textile fibres, and tire wear particles (TWP). Together, these sources account for over 25 % of global MP emissions, nearly 3 million tonnes annually, yet they are rarely singled out in research or regulation. Each presents unique analytical and regulatory challenges due to their complex compositions, diffuse emissions, and strong ties to daily life. We enumerate current knowledge on their environmental pathways, emission estimates, and detection methods, highlighting the need for …

Development Of Green Port Index : A Tool For Assessing Ports Based On Implementation Of Ghg Emission Reduction Measures, Mamadou Lamin Bajo

World Maritime University Dissertations

No abstract provided.

Feasibility Of Adopting Reformed Methanol–High Temperature Proton Exchange Membrane Fuel Cell Technology For The Propulsion Of Seagoingvessel, Toochukwu Patricia Obasi

World Maritime University Dissertations

No abstract provided.

The Importance Of Green Ammonia In Namibia's Decarbonisation Of Shipping : Economic Prospects And Port Infrastructure Obstacles, Lazarus Shiimwaningi Emvula

World Maritime University Dissertations

No abstract provided.

Techno-Economic Assessment Of Photovoltaic And Wind Energy Applications At Monkey Bay Port, Dickson Alfonso Kunyada

World Maritime University Dissertations

No abstract provided.

Exploring Challenges And Opportunities For Green Shipbuilding In South Africa : A Maritime Energy Management Perspective, Masego Mmamolobye Lucia Mosupye

World Maritime University Dissertations

No abstract provided.

An Analysis Of Renewable Energy Capture Utilization For Mpulungu Harbour, Dorica Nayame

World Maritime University Dissertations

No abstract provided.

Feasibility Of Onshore Power Supply For Port Electrification : A Business Case For Ports, Atti Abbas Shah

World Maritime University Dissertations

No abstract provided.

Examining The Perception Of Maritime Instructors In Upskilling And Reskilling Seafarers Towards Decarbonization, Michelle Margallo

World Maritime University Dissertations

No abstract provided.

Marine Environmental Protection : An Investigation Into Existing Global Laws Addressing Marine Plastic Pollution, Maryland De Castro

World Maritime University Dissertations

No abstract provided.

Navigating Equity In The Digital Era : Addressing Challenges And Advancing Rights Of Female Seafarers Through Policy Reform, And Artificial Intelligence, Margaret Dixon

World Maritime University Dissertations

No abstract provided.

Emerging Policies On Marine Biodiversity Beyond National Jurisdiction Governance, Jessie Neta Jeffrey

World Maritime University Dissertations

No abstract provided.

An Assessment Of The Legal Framework For Prosecuting Iuu Fishing In Nigeria, Lydia Salla Kadiri

World Maritime University Dissertations

No abstract provided.

Decarbonization And Climate Justice : Challenges And The Effect On Shipowners, Sofiana Kontouri

World Maritime University Dissertations

No abstract provided.

Plastic Pollution In The Arctic Region And International Rules : Applicability And Limitations, Zhanfeng Lang

World Maritime University Dissertations

No abstract provided.

Technology Transfer In The Implementation Of The Biodiversity Beyond National Jurisdiction Agreement, Christine Nzambi Mulatya

World Maritime University Dissertations

No abstract provided.

Decarbonization Of The Fishing Fleet In The Galapagos Islands : Governance Challenges And Opportunities For Implementing Renewable Energy Sources, Byron Eduardo Robles Romero

World Maritime University Dissertations

No abstract provided.

Jurisdiction Of Vessel-Source Pollution In The Eez Under Unclos : A Case Study On China, Yang Zhang

World Maritime University Dissertations

No abstract provided.

Preparedness And Response To Oil And Biofuel Spills : A Case Study Of The Western Indian Ocean, Soifoine Abdillah

World Maritime University Dissertations

No abstract provided.

Towards Zero Emissions Ports In Saudi Arabia : Drivers, Barriers, And Opportunities, Saad Hulil S Alshahrani

World Maritime University Dissertations

No abstract provided.