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Full-Text Articles in Physical Sciences and Mathematics

Finding Aid For The Evelyn Uhrhan Irving Collection (Mum00146) Jan 2022

Finding Aid For The Evelyn Uhrhan Irving Collection (Mum00146)

Archives & Special Collections: Finding Aids (alphabetical)

Correspondence of modern language professor Evelyn Uhrhan Irving with various public officials and media outlets on foreign policy and domestic matters.


Introduction To Analytics And Data Science, Leila Halawi, Amal Clarke, Kelly George Jan 2022

Introduction To Analytics And Data Science, Leila Halawi, Amal Clarke, Kelly George

Publications

Learning Objectives

  • Identify the different data types and measurements

  • Identify the need for data and data sources

  • Explain data partitioning and honest assessment

  • Identify the necessity of data preparation and curation

  • Identify the data preparation process

  • Explore SAS VIYA platform and import data


Cansafe: An Mtd Based Approach For Providing Resiliency Against Dos Attack Within In-Vehicle Networks, Ayan Roy, Sanjay Kumar Madria Jan 2022

Cansafe: An Mtd Based Approach For Providing Resiliency Against Dos Attack Within In-Vehicle Networks, Ayan Roy, Sanjay Kumar Madria

Computer Science Faculty Research & Creative Works

Trending towards autonomous transportation systems, modern vehicles are equipped with hundreds of sensors and actuators that increase the intelligence of the vehicles with a higher level of autonomy, as well as facilitate increased communication with entities outside the in-vehicle network. However, increase in a contact point with the outside world has exposed the controller area network (CAN) of a vehicle to remote security vulnerabilities. In particular, an attacker can inject fake high priority messages within the CAN through the contact points, while preventing legitimate messages from controlling the CAN (Denial-of-Service (DoS) attack). In this paper, we propose a Moving Target …


Distributed Decision Making For V2v Charge Sharing In Intelligent Transportation Systems, Punyasha Chatterjee, Pratham Majumder, Arpita Debnath, Sajal K. Das Jan 2022

Distributed Decision Making For V2v Charge Sharing In Intelligent Transportation Systems, Punyasha Chatterjee, Pratham Majumder, Arpita Debnath, Sajal K. Das

Computer Science Faculty Research & Creative Works

Electric vehicles (EVs) have emerged in the intelligent transportation system (ITS) to meet the increasing environmental concerns. To facilitate on-demand requirement of EV charging, vehicle-to-vehicle (V2V) charge transfer can be employed. However, most of the existing approaches to V2V charge sharing are centralized or semi-centralized, incurring huge message overhead, long waiting time, and infrastructural cost. In this paper, we propose novel distributed heuristic algorithms for V2V charge sharing based on the multi-criteria decision-making policy. The problem is mapped to an alias classical problem (i.e., optimum matching in weighted bipartite graphs), where the goal is to maximize the matching cardinality while …


Delivery With Uavs: A Simulated Dataset Via Ats, Giulio Rigoni, Cristina M. Pinotti, Bhumika, Debasis Das, Sajal K. Das Jan 2022

Delivery With Uavs: A Simulated Dataset Via Ats, Giulio Rigoni, Cristina M. Pinotti, Bhumika, Debasis Das, Sajal K. Das

Computer Science Faculty Research & Creative Works

We consider a delivery food service operated by Unmanned Aerial Vehicles (UAVs). Due to the absence of a dataset on UAVs deliveries in the literature, and since it is not possible to perform real tests, we create a dataset using an open-Air Traffic Simulator (ATS). Precisely, we converted a set of food deliveries operated by wheeled vehicles, proposed in the literature [1], into a set of simulated UAVs deliveries. For each delivery, we ran a UAV flight from the source to the destination. The results showed that, as expected, the UAV's course is shorter than the vehicle trajectory on the …


Active Learning Augmented Folded Gaussian Model For Anomaly Detection In Smart Transportation, Venkata Praveen Kumar Madhavarapu, Prithwiraj Roy, Shameek Bhattacharjee, Sajal K. Das Jan 2022

Active Learning Augmented Folded Gaussian Model For Anomaly Detection In Smart Transportation, Venkata Praveen Kumar Madhavarapu, Prithwiraj Roy, Shameek Bhattacharjee, Sajal K. Das

Computer Science Faculty Research & Creative Works

Smart transportation networks have become instrumental in smart city applications with the potential to enhance road safety, improve the traffic management system and driving experience. A Traffic Message Channel (TMC) is an IoT device that records the data collected from the vehicles and forwards it to the Roadside Units (RSUs). This data is further processed and shared with the vehicles to inquire the fastest route and incidents that can cause significant delays. The failure of the TMC sensors can have adverse effects on the transportation network. In this paper, we propose a Gaussian distribution-based trust scoring model to identify anomalous …


Spade: Multi-Stage Spam Account Detection For Online Social Networks, Federico Concone, Giuseppe Lo Re, Marco Morana, Sajal K. Das Jan 2022

Spade: Multi-Stage Spam Account Detection For Online Social Networks, Federico Concone, Giuseppe Lo Re, Marco Morana, Sajal K. Das

Computer Science Faculty Research & Creative Works

In recent years, Online Social Networks (OSNs) have radically changed the way people communicate. The most widely used platforms, such as Facebook, Youtube, and Instagram, claim more than one billion monthly active users each. Beyond these, news-oriented micro-blogging services, e.g., Twitter, are daily accessed by more than 120 million users sharing contents from all over the world. Unfortunately, legitimate users of the OSNs are mixed with malicious ones, which are interested in spreading unwanted, misleading, harmful, or discriminatory content. Spam detection in OSNs is generally approached by considering the characteristics of the account under analysis, its connection with the rest …


A Novel Echo State Network Autoencoder For Anomaly Detection In Industrial Iot Systems, Fabrizio De Vita, Giorgio Nocera, Dario Bruneo, Sajal K. Das Jan 2022

A Novel Echo State Network Autoencoder For Anomaly Detection In Industrial Iot Systems, Fabrizio De Vita, Giorgio Nocera, Dario Bruneo, Sajal K. Das

Computer Science Faculty Research & Creative Works

The Industrial Internet of Things (IIoT) technology had a very strong impact on the realization of smart frameworks for detecting anomalous behaviors that could be potentially dangerous to a system. In this regard, most of the existing solutions involve the use of Artificial Intelligence (AI) models running on Edge devices, such as Intelligent Cyber Physical Systems (ICPS) typically equipped with sensing and actuating capabilities. However, the hardware restrictions of these devices make the implementation of an effective anomaly detection algorithm quite challenging. Considering an industrial scenario, where signals in the form of multivariate time-series should be analyzed to perform a …


Mobility Management In Industrial Iot Environments, Marco Pettorali, Francesca Righetti, Carlo Vallati, Sajal K. Das, Giuseppe Anastasi Jan 2022

Mobility Management In Industrial Iot Environments, Marco Pettorali, Francesca Righetti, Carlo Vallati, Sajal K. Das, Giuseppe Anastasi

Computer Science Faculty Research & Creative Works

The Internet Engineering Task Force (IETF) has defined the 6TiSCH architecture to enable the Industrial Inter-net of Things (IIoT). Unfortunately, 6TiSCH does not provide mechanisms to manage node mobility, while many industrial applications involve mobile devices (e.g., mobile robots or wearable devices carried by workers). In this paper, we consider the Synchronized Single-hop Multiple Gateway framework to manage mobility in 6TiSCH networks. For this framework, we address the problem of positioning Border Routers in a deployment area, which is similar to the "Art Gallery"problem, proposing an efficient deployment policy for Border Routers based on geometrical rules. Moreover, we define a …


Creation Of A Neural Network For The American Sign Language To Russian Translation App, John T. Simmons Jan 2022

Creation Of A Neural Network For The American Sign Language To Russian Translation App, John T. Simmons

Capstone Projects

  1. A large population of people utilize American Sign Language for their primary method of communication.
  2. No commercially available product is available for these people for when they need to communicate with speakers of a foreign language.
  3. We must investigate methods to make communication between these two parties easier and more accessible.
  4. By using a neural network to classify images of American Sign Language letters, we can build a service to make translation of American Sign Language into foreign languages possible.


Maintenance Optimization In A Digital Twin For Industry 4.0, Abhijit Gosavi, Vy Khoi Le Jan 2022

Maintenance Optimization In A Digital Twin For Industry 4.0, Abhijit Gosavi, Vy Khoi Le

Engineering Management and Systems Engineering Faculty Research & Creative Works

The advent of Internet of Things and artificial intelligence in the era of Industry 4.0 has transformed decision-making within production systems. In particular, many decisions that previously required significant human activity are now made automatically with minimal human intervention via so-called digital twins (DTs). In the context of maintenance and reliability modeling, this naturally calls for new paradigms that can be seamlessly integrated within DTs for decision-making. The input data for time to failure needed in reliability computations are directly collected from the work center in a digital setting and often do not satisfy a known distribution. A neural network …


U.S. Public Opinion Of Reproductive Control Options For Free-Roaming Horses On Western Public Lands, S. Nicole Frey, Jeffrey L. Beck, John Derek Scasta, Loretta Singletary Jan 2022

U.S. Public Opinion Of Reproductive Control Options For Free-Roaming Horses On Western Public Lands, S. Nicole Frey, Jeffrey L. Beck, John Derek Scasta, Loretta Singletary

Human–Wildlife Interactions

Free-roaming horses (Equus ferus caballus; horses) inhabit public rangelands located primarily in 10 western U.S. states. Recent horse population increases are impacting rangeland ecosystems, native wildlife species and their habitats, and exacerbating conflicts with domestic livestock grazing. While contraceptives and physical sterilization are promising options to manage horse herd levels, public opinion concerning the use of fertility control is not well understood. To better inform policymakers, we completed a rigorous study of a random sample of public land stakeholders across the United States (n = 3,500) in 2020 using a Likert scale online survey to assess their …


Re-Storying Grant Creek: A Case Study Of Relational Dynamics On A Degraded Montana Stream, Seamus Rucci Land Jan 2022

Re-Storying Grant Creek: A Case Study Of Relational Dynamics On A Degraded Montana Stream, Seamus Rucci Land

Graduate Student Theses, Dissertations, & Professional Papers

The UN Decade on Ecosystem Restoration began in 2021, and after a history of contentious ethical debates, ecological restoration is increasingly portrayed as a viable framework for combating environmental degradation and supporting more healthy and stable social-ecological systems. The proposed ecological restoration of Grant Creek, a degraded stream near Missoula, Montana, offers an opportunity to connect a restoration site to the broader, rapidly growing field of restoration practice. It also allows the opportunity to forward the ‘relational turn’ proposed by many in the sustainability sciences as an ontological and methodological means to move beyond positivist portrayals of social-ecological systems, which …


Formulation, Structure, And Applications Of Therapeutic, Amino Acid, And Water-Based Deep Eutectic Solvents, Md Sajjadur Rahman Jan 2022

Formulation, Structure, And Applications Of Therapeutic, Amino Acid, And Water-Based Deep Eutectic Solvents, Md Sajjadur Rahman

Electronic Theses and Dissertations

In the design of greener chemicals, deep eutectic solvents (DESs) are considered as one of the most versatile alternative solvents with widespread applications. DESs have the advantages of being nonflammable with negligible vapor pressure compared to traditional solvents. They share many characteristics of ionic liquids, but DESs are cheaper to formulate, typically nontoxic, recyclable, biodegradable, and are suitable for use with biological systems. In my Ph.D. research, three types of emerging and unconventional types of DESs, namely therapeutic DES (THEDES), amino acid-based DES (AADES), and water-based DES (WDES), have been investigated. To formulate these DES easily available and cheaper chemicals, …


Soil Hydro-Physical Properties, Computed Tomography Measured Pore Parameters, And Soil Health Indicators As Influenced By Tillage And Crop Rotation Systems, Goutham Thotakuri Jan 2022

Soil Hydro-Physical Properties, Computed Tomography Measured Pore Parameters, And Soil Health Indicators As Influenced By Tillage And Crop Rotation Systems, Goutham Thotakuri

Electronic Theses and Dissertations

Long-term tillage and crop rotation systems are important agricultural management practices as these can have direct impact on the soil’s key properties. The objectives of this study were to (ⅰ) quantify the soil pore characteristics under long-term tillage and crop rotation using X-ray computed tomography (XCT) and to assess the relationships between XCT-measured pore parameters and soil hydro-physical properties; and (ⅱ) evaluate the impacts of long-term tillage and crop rotation on select soil health indicators. The objective (ⅰ) was carried out at Haskell Agricultural Laboratory (HAL), Concord, NE; and objective (ⅰi) was carried out at South Central Agricultural Laboratory (SCAL), …


Study On Performance Of Pruned Cnn-Based Classification Models, Mengling Deng Jan 2022

Study On Performance Of Pruned Cnn-Based Classification Models, Mengling Deng

Electronic Theses and Dissertations

Convolutional Neural Network (CNN) is a neural network developed for processing image data. CNNs have been studied extensively and have been used in numerous computer vision tasks such as image classification and segmentation, object detection and recognition, etc. [1] Although, the CNNs-based approaches showed humanlevel performances in these tasks [2], they require heavy computation in both training and inference stages, and the models consist of millions of parameters. This hinders the development and deployment of CNN-based models for real world applications. Neural Network Pruning and Compression techniques have been proposed [3, 4] to reduce the computation complexity of trained CNNs …


It's Not Just No-Till: Crop Rotations Are Key To Improving Soil Quality And Grain Yields At Dakota Lakes Research Farm, Natalie Sturm Jan 2022

It's Not Just No-Till: Crop Rotations Are Key To Improving Soil Quality And Grain Yields At Dakota Lakes Research Farm, Natalie Sturm

Electronic Theses and Dissertations

No-till is increasingly promoted as a vital agricultural practice to address the challenge of improving soil quality while maintaining the ability to produce food, feed, fuel, and fiber. However, questions remain regarding 1) how different crop rotations impact soil quality under no-till management specifically and 2) whether significant improvements in soil quality can be made without negatively impacted crop yields. In this study, we demonstrate that even under the same long-term no-till management, differences in grain yields and soil biological, chemical, and physical properties exist between crop rotations at Dakota Lakes Research Farm in central South Dakota. We propose that …


Combining Soil Health And Fertility Measurements To Improve The Accuracy Of Predicting Corn Grain Yield Responses To P And K Fertilization, Benjamin Groebner Jan 2022

Combining Soil Health And Fertility Measurements To Improve The Accuracy Of Predicting Corn Grain Yield Responses To P And K Fertilization, Benjamin Groebner

Electronic Theses and Dissertations

Researchers have pointed to changes in climate and land management practices to justify the need to reevaluate the accuracy of current South Dakota (SD) corn (Zea mays L.) P and K fertilizer recommendations. Also, an increase in soil health understanding has created the potential for soil health measurements to be used to improve the accuracy of these recommendations. The objectives for this study were to 1) evaluate the current P and K critical values and 2) determine the effect of including soil health indicators on improving fertilizer recommendation accuracy. This project was conducted throughout central and eastern SD from 2019-2021 …


Disentangling The Complex Evolutionary History Of Invasive Russian Thistle: Phylogenetic Relationships, The Role Of Hybridization, And Public Engagement, Deva Raj Khanal Jan 2022

Disentangling The Complex Evolutionary History Of Invasive Russian Thistle: Phylogenetic Relationships, The Role Of Hybridization, And Public Engagement, Deva Raj Khanal

Electronic Theses and Dissertations

Invasive species are forces of environmental, economic, and social change with detrimental impacts on ecosystems, commerce, agriculture, and human health. However, we still have a poor understanding of the processes that could be driving invasive potential. Hybridization may contribute to the establishment and spread of invasive lineages, as it may enhance genetic variation and facilitate rapid adaptation. Focusing on Russian thistle (Salsola tragus s.l., family Amaranthaceae) and closely related species, my thesis aims to clarify phylogenetic relationships and investigate how hybridization has shaped the invasion dynamics of these lineages. Known as one of the fastest plant invasions in the United …


A Post-Pneumonia Epizootic Evaluation Of The Rapid City, South Dakota Bighorn Sheep Herd, Amanda N. Ensrud Jan 2022

A Post-Pneumonia Epizootic Evaluation Of The Rapid City, South Dakota Bighorn Sheep Herd, Amanda N. Ensrud

Electronic Theses and Dissertations

Pneumonia is a major factor affecting populations of free-ranging bighorn sheep (Ovis canadensis) across western North America. Pneumonia can occur in large-scale epizootics, during which greater than half of the population typically dies. After these epizootics, surviving ewes continue to conceive and bear lambs. However, lamb recruitment may remain low due to periodic or annual pneumonia outbreaks causing high lamb mortality rates, sometimes greater than 90%. Our study focused on the Rapid City, South Dakota bighorn sheep (BHS) herd that has recorded pneumonia-induced population decline since 2009. The first objective was to improve lamb health and survival by identifying and …


Post-Fledging Habitat Selection And Movements Of Juvenile Mallards In The Prairie Pothole Region, Cynthia E. Anchor Jan 2022

Post-Fledging Habitat Selection And Movements Of Juvenile Mallards In The Prairie Pothole Region, Cynthia E. Anchor

Electronic Theses and Dissertations

The Prairie Pothole Region (PPR) of North America provides critical habitat for waterfowl across life stages, but anthropogenic changes to the landscape have negatively impacted habitat quality for waterfowl. The mallard (Anas platyrhynchos) is abundant and socioeconomically valuable in the PPR, as it is a preferred target species of waterfowl hunters. Extensive research has evaluated breeding ecology of mallards in the PPR, but the period between juvenile mallards fledging and migrating has rarely been studied. The post-fledging ecology of juvenile mallards is a vital consideration for comprehensive waterfowl management. Further, juvenile mallards are a significant portion of hunter harvest at …


Northern Great Plains Saline Sodic Soil Development, Classification, Remediation, And Management., Shaina Westhoff Jan 2022

Northern Great Plains Saline Sodic Soil Development, Classification, Remediation, And Management., Shaina Westhoff

Electronic Theses and Dissertations

Soil salinity and sodicity are issues of growing concern in the United States (U.S.) and globally. Knowledge gaps for glaciated, dryland salt-affected soils exist because much original salinity and sodicity research focused on irrigated systems. Land managers are being asked to produce food, feed, fiber, and fuel for an expanding global population. The number of land managers and crop advisors who are affected by these soils is increasing. Addressing salinity and sodicity knowledge gaps will be critical for their success. Salinity and sodicity have been impeding crop productivity since the advent of cultivation. Saline and sodic soils form via multiple …


Dynamics Of Mutualism In A Two Prey, One Predator System With Variable Carrying Capacity, Randy Huy Lee Jan 2022

Dynamics Of Mutualism In A Two Prey, One Predator System With Variable Carrying Capacity, Randy Huy Lee

UNF Graduate Theses and Dissertations

We considered the livelihood of two prey species in the presence of a predator species. To understand this phenomenon, we developed and analyzed two mathematical models considering indirect and direct mutualism of two prey species and the influence of one predator species. Both types of mutualism are represented by an increase in the preys' carrying capacities based on direct and indirect interactions between the prey. Because of mutualism, as the death rate parameter of the predator species goes through some critical value, the model shows transcritical bifurcation. Additionally, in the direct mutualism model, as the death rate parameter decreases to …


Bounded-Degree Plane Geometric Spanners: Connecting The Dots Between Theory And Practice, Matthew Alexander Graham Jan 2022

Bounded-Degree Plane Geometric Spanners: Connecting The Dots Between Theory And Practice, Matthew Alexander Graham

UNF Graduate Theses and Dissertations

The construction of bounded-degree plane geometric spanners has been a focus of interest since 2002 when Bose, Gudmundsson, and Smid proposed the first algorithm to construct such spanners. To date, eleven algorithms have been designed with various trade-offs in degree and stretch factor. We have implemented these sophisticated algorithms in C++ using the CGAL library and experimented with them using large synthetic and real-world pointsets. Our experiments have revealed their practical behavior and real-world efficacy. We share the implementations via GitHub for broader uses and future research.

We present a simple practical algorithm, named AppxStretchFactor, that can estimate stretch factors …


Measuring Vegetation Density In Marsh Grass Photographs Using Convolutional Neural Networks, Lucas W. Welch Jan 2022

Measuring Vegetation Density In Marsh Grass Photographs Using Convolutional Neural Networks, Lucas W. Welch

UNF Graduate Theses and Dissertations

A marsh is a wetland dominated by various species of grasses rather than trees. It supports an important ecosystem, providing habitats for many kinds of animals and posing a crucial impact on coastal climates. Marshes are rapidly changing, and it is vital for scientists to track these changes to understand the health of them. To do so, biologists perform vegetation monitoring to estimate the coverage of vegetation in an area of marsh. This task often calls for extensive human labor carefully examining pixels in photos of marsh sites to calculate vegetation density for a variety of marsh grass species. This …


Frequent Mental Distress Among Adults In The United States And Its Association With Socio-Demographic Characteristics, Unhealthy Lifestyle, And Chronic Physical Health Status, Mamunur Rashid, M. Mazharul Islam, Aiping Li, Naima Shifa Jan 2022

Frequent Mental Distress Among Adults In The United States And Its Association With Socio-Demographic Characteristics, Unhealthy Lifestyle, And Chronic Physical Health Status, Mamunur Rashid, M. Mazharul Islam, Aiping Li, Naima Shifa

Mathematics Faculty Publications

Frequent mental distress (FMD) is a measure of poor mental health days for at least 14 days out of 30 days. It is one of the important dimensions of the health-related quality of life. The underlying causes of FMD are diverse. However, the issue has not been explored extensively due to the lack of reliable data on mental health. The aim of this study was to examine the level and trends of FMD among the adults of the United States (US) and identify the socio-demographic, lifestyles, and chronic health outcomes related correlates of FMD. The data for the study was …


Preparation Of Ion-Selective Membrane And Electrode Using Cobalt Porphyrin As Ionophore For Anion Detection, Kawisara Longsakpreecha Jan 2022

Preparation Of Ion-Selective Membrane And Electrode Using Cobalt Porphyrin As Ionophore For Anion Detection, Kawisara Longsakpreecha

Chulalongkorn University Theses and Dissertations (Chula ETD)

In this study, the synthesis of the 5,10,15,20-tetrakis(4-dodecyloxyphenyl)porphyrin cobalt(II) complex (CoL) was carried out through a condensation reaction of 4-n-dodecyloxybenzaldehyde and pyrrole, followed by the metalation reaction of cobalt(II) acetate with meso-tetra(4-alkyloxyphenyl) porphyrin (L2) to obtain CoL. Characterization of CoL was conducted using physical methods such as 1H-NMR, 13C-NMR, and MALDI-TOF to confirm CoL structure and purity. CoL was utilized as an ionophore to fabricate the ion selective membrane (ISM) and ion selective electrode (ISE) for the detection of ClO4-. The composition of the ISM, including polymer (PVC), plasticizer (NPOE), cationic additive (TDMACl), and ionophore (CoL), was optimized for ISE …


Characterizing Properties Of Implicit Dependence Copulas And Extreme Copulas, Noppawit Yanpaisan Jan 2022

Characterizing Properties Of Implicit Dependence Copulas And Extreme Copulas, Noppawit Yanpaisan

Chulalongkorn University Theses and Dissertations (Chula ETD)

No abstract provided.


Synthesis And Process Optimization Of Colloidal Unimolecular Polymer, Cup, Particle Formation, And Its Interfacial Surface Tension Behavior, Ashish Zore Jan 2022

Synthesis And Process Optimization Of Colloidal Unimolecular Polymer, Cup, Particle Formation, And Its Interfacial Surface Tension Behavior, Ashish Zore

Doctoral Dissertations

"Colloidal Unimolecular Polymer (CUP) particles are 3-9 nm size single-chain polymer nanoparticles that are made from amphiphilic acrylic co-polymers using the process of water reduction. The formation of CUP particles was driven by the polymer-polymer interactions being greater than polymer-solvent interactions as well as the charge-charge repulsion due to the increasing dielectric of the medium. CUPs provide a surfactant or additive-free nanoparticle system that was useful for studying the interfacial behavior of pure aqueous nanoparticles using a maximum bubble pressure tensiometer. The equilibrium surface tension shows a dependence on concentration and the charge density of the CUP particle. The equilibrium …


Establishing Pteridine Metabolism In A Breast Cancer Cell Model And Quantification Of Silver Nanoparticle Interactions With Yeast Cells Using Mass Spectrometry, Lindsey Katherine Rasmussen Jan 2022

Establishing Pteridine Metabolism In A Breast Cancer Cell Model And Quantification Of Silver Nanoparticle Interactions With Yeast Cells Using Mass Spectrometry, Lindsey Katherine Rasmussen

Doctoral Dissertations

"Recent advances in analytical methods have furthered the quantitative insights that can be gleaned from cellular analyses, with applications in cancer and nanoparticle research. In the first part of the research presented, a recently developed HPLC-MS/MS method was advanced to elucidate pteridine metabolism in an isogenic progressive MCF10A breast cancer cell model. The folate-derived pteridine pathway in breast cells was established by individually dosing cell cultures with folic acid and 15 pteridines. Eight potential pteridine biomarkers in breast cancer cells were identified including pterin and isoxanthopterin, which yielded the first in vitro evidence for the cellular metabolisms behind previously reported …