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Articles 6571 - 6600 of 291657
Full-Text Articles in Physical Sciences and Mathematics
Rethinking Ai Literacy Education In Higher Education: Bridging Risk Perception And Responsible Adoption, Shasha Yu, Fiona Carroll, Barry L. Bentley
Rethinking Ai Literacy Education In Higher Education: Bridging Risk Perception And Responsible Adoption, Shasha Yu, Fiona Carroll, Barry L. Bentley
School of Professional Studies
As AI becomes increasingly embedded across societal domains, understanding how future AI practitioners—particularly technology students—perceive its risks is essential for responsible development and adoption. This study analyzed responses from 139 students in Computer Science, Data Science/Data Analytics, and other disciplines using both explicit AI risk ratings and scenario-based assessments of risk and adoption willingness. Four key findings emerged: (1) Students expressed substantially higher concern for concrete, explicitly stated risks than for abstract or scenario-embedded risks; (2) Perceived risk and willingness to adopt AI demonstrated a clear inverse relationship; (3) Although technical education narrowed gender differences in risk awareness, male students …
Computationally Modelling Nmda Blockages Within A Neural Network, Anya Raetsch
Computationally Modelling Nmda Blockages Within A Neural Network, Anya Raetsch
UNH URC Open (2026 and after)
The N-Methyl-D-Aspartate (NMDA) Receptor is fundamentally important to memory formation within the brain due to its control of calcium entry into the cell. In recent years, there has been an increased interest in long-term effects of NMDA blockages on the brain, due to the “re-wiring” of communication channels (synapses) between neurons. This project models the effects of NMDA blockages due to drugs such as Ketamine, and how the blocking of NMDA receptors affects firing rates, which can then be applied to studying long-term plasticity within the neural hierarchies. Using the Nest Online Simulator, a 50x50 grid of neurons was created …
A Note On Asymptotics Of Estimators For Axially Symmetric Processes On The Sphere, Haimeng Zhang, Chunfeng Huang, Xiaohuan Xue, A.L.A.R.R. Thanuja, Bukola O. Adaramola
A Note On Asymptotics Of Estimators For Axially Symmetric Processes On The Sphere, Haimeng Zhang, Chunfeng Huang, Xiaohuan Xue, A.L.A.R.R. Thanuja, Bukola O. Adaramola
Research, Publications & Creative Work
Axially symmetric processes, those stationary in longitude but nonstationary across latitude, provide a flexible and physically meaningful class of models for global environmental data. Despite their wide use, the asymptotic properties of classical method-of-moments (MOM) estimators for these processes remain largely unexamined. In this work, we investigate MOM estimators of covariances and cross-variograms for axially symmetric Gaussian processes observed on regular latitude-longitude grids. First, we show that MOM covariance estimators are asymptotically biased. We then examine MOM estimators of cross-variograms, and prove that they are unbiased. However, using the block circulant structure of the covariance matrix and its Fourier diagonalization, …
Soil Organic Carbon And Soil Health Property Responses To Land Management Across Topographic Positions, Mia D. Makovsky
Soil Organic Carbon And Soil Health Property Responses To Land Management Across Topographic Positions, Mia D. Makovsky
All Graduate Theses, Dissertations, and Other Capstone Projects
uring the last ice age, ice sheets advanced and retreated across the upper Midwest, leaving behind a landscape characterized by poorly drained hummocky topography. Well-aerated soils have formed on uplands and lowlands are dominated by hydric soils. These wetlands and hydric soils have potential to store large quantities of carbon, particularly compared to the well-aerated uplands, but many have been drained and cultivated for decades. Conservation agriculture methods have emerged to protect and conserve soil health from negative effects due to cultivation.The purpose of this study is to determine how agricultural management practices and landscape properties (e.g, topographic position) affect …
Pullulan Production From Lignocellulosic Plant Biomass Or Starch-Containing Processing Coproduct Hydrolysates, Thomas P. West
Pullulan Production From Lignocellulosic Plant Biomass Or Starch-Containing Processing Coproduct Hydrolysates, Thomas P. West
Faculty Publications
The complex polysaccharide pullulan is characterized as a glucose-containing biopolymer that is both water-soluble and neutral in polarity. A variety of commercial applications exist for pullulan, including its utilization as a flocculant, a blood plasma substitute, a food additive, a dielectric material, an adhesive, or a packaging film. The fungus Aureobasidium pullulans has used several hydrolysates derived from plant biomass or starch-containing processing coproducts to support polysaccharide production. These include various plant biomass or processing coproduct streams such as lignocellulosic-containing peat, prairie grass, stalks, hulls, straw, shells, and pods or starch-containing coproducts from the processing of corn, rice, jackfruit seeds, …
Reinforcement Learning-Enabled Control And Design Of Rigid-Link Robotic Fish: A Comprehensive Review, Nhat Dinh, Darion Vosbein, Yuehua Wang, Qingsong Cui
Reinforcement Learning-Enabled Control And Design Of Rigid-Link Robotic Fish: A Comprehensive Review, Nhat Dinh, Darion Vosbein, Yuehua Wang, Qingsong Cui
Faculty Publications
With the rising demand for maritime surveys of infrastructure, energy resources, and environmental conditions, autonomous robotic fish have emerged as a promising solution with their biomimetic propulsion, agile motion, efficiency, and capacity for underwater inspection, monitoring, data collection, and exploration tasks in complex aquatic environments. Inspired by fish spines, rigid-link fish robots (RLFRs), a category of robotic fish, are widely utilized in robotics research and applications. Their rigid, actuated joints enable them to reproduce the undulatory locomotion and high maneuverability of biological fishes, while the modular nature of rigid links between joints makes them cost-effective and easy to assemble. This …
Fulbright Project In Iceland In The Summer Of 2026, Irina Filina
Fulbright Project In Iceland In The Summer Of 2026, Irina Filina
Nebraska Academy of Sciences: Programs and Proceedings
This upcoming Fulbright project is inspired by an ongoing debate in the scientific community about the tectonic origin of Iceland. A long-standing theory of Iceland’s formation by excessive magmatism at the Mid-Atlantic spreading center over the well-known hot spot (i.e., oceanic crustal affinity) was recently challenged by the alternative hypothesis that the Icelandic crust is continental in nature and is being stretched and gradually modified by magmatic processes. Based on this hypothesis, a new sunken continent, Icelandia, has been proposed. One of the foundations for the proposed Icelandia is the presence of felsic lavas (indicative of continental flavor in the …
Open Scholarly Information Systems: Status Quo, Challenges, Opportunities, Hannah Bast, Guillaume Cabanac, Paolo Manghi, Jian Wu, Marcel R. Ackermann
Open Scholarly Information Systems: Status Quo, Challenges, Opportunities, Hannah Bast, Guillaume Cabanac, Paolo Manghi, Jian Wu, Marcel R. Ackermann
Computer Science Faculty Publications
Over the past 30 years, a rich ecosystem of scholarly information systems has developed that openly provide their services to the scientific community. These systems include aggregators of bibliographic metadata (e.g., DBLP, OpenCitations, OpenAIRE Graph, OpenAlex, ORKG, Semantic Scholar, CiteSeerX, and CORE); publication, data, and software repositories (e.g., Arxiv.org, Figshare, Zenodo, Software Heritage, and Dataverse); and PID authorities (e.g., ORCID, ROR, Crossref, and DataCite). This interdisciplinary Dagstuhl Seminar "Open Scholarly Information Systems: Status Quo, Challenges, Opportunities" (25381) was the first of its kind to bring together practitioners from this ecosystem, as well as researchers investigating related questions or relying on …
Ordered Mini-Batch Training For Differentially Private And Encrypted Logistic Regression, Ryan Leone
Ordered Mini-Batch Training For Differentially Private And Encrypted Logistic Regression, Ryan Leone
Theses, Dissertations and Culminating Projects
Logistic regression has found extensive use as a supervised machine learning algorithm due to its simplicity and efficiency in binary and multivariate classification tasks. As data sharing grows across connected devices, safeguarding sensitive personal and industrial information is of increased importance. Privacy-preserving machine learning techniques such as differential privacy and homomorphic encryption offer mathematically rigorous security guarantees, but introduce difficult accuracy, privacy loss, and computational overhead issues. This thesis investigates PPML for logistic regression through a collaborative mini-batch training framework. I propose and implement an ordered mini-batch strategy, compare it to standard shuffled methods, then integrate differential privacy noise injection …
Holistic Stormwater Management In The Bound Brook River Basin, New Jersey, Sana Mirza
Holistic Stormwater Management In The Bound Brook River Basin, New Jersey, Sana Mirza
Theses, Dissertations and Culminating Projects
This dissertation presents a holistic framework for stormwater management in the Bound Brook River Basin, an urban watershed in central New Jersey that faces chronic nutrient enrichment and climate-driven hydrologic changes. The research integrates water-quality trend analysis, hydrologic modeling, and low-impact development (LID) optimization to assess current and projected watershed responses. By combining empirical monitoring data with downscaled climate simulations and spatial prioritization, the study utilizes a holistic approach for stormwater management planning. The first objective was to characterize nutrient dynamics and hydrologic transport pathways for nitrogen, phosphorus, and total suspended solids (TSS) from 2004 to 2019. Using bi-monthly monitoring …
An Integrated Approach To Groundwater Management In Northern New Jersey Watersheds, Toritseju Oyen
An Integrated Approach To Groundwater Management In Northern New Jersey Watersheds, Toritseju Oyen
Theses, Dissertations and Culminating Projects
Groundwater deterioration has emerged as a pressing global concern, with widespread observations of declining water quality in various regions. The predominant cause of this deterioration is attributed to anthropogenic activities, which are deeply intertwined with daily human practices that contaminate water resources. Over the decades, many forested and wetland areas have been converted mainly for increased urbanization and industrialization use in northern New Jersey. The region’s watershed, already characterized as a low-yield aquifer, is facing deterioration because of continuous change in land cover. Anthropogenic activities aimed at providing solutions to problems, such as food scarcity, icy roads during the winter …
Hierarchy And Ideology Antagonism: Artificial Intelligence In Ridley Scott's Alien, Grace Anastasia Pula
Hierarchy And Ideology Antagonism: Artificial Intelligence In Ridley Scott's Alien, Grace Anastasia Pula
Theses, Dissertations and Culminating Projects
This thesis examines the objectively threatening structure of artificial intelligence (AI) in the narrative plot of Alien and how it exerts control over the humans. Using a structuralist approach with Louis Althusser's Ideological State Apparatuses (ISAs), I will examine the character relationships and how an android, Ash, enforces a patriarchal, hierarchical system. Drawing on Mark Coeckelbergh’s AI Ethics and Jacques Ellul’s The Technological Society, I will outline broader fears that technology will surpass human intellect and serve a destructive function within an oppressive system. Analyzing two examples of AI characters, the film showcases capitalist ambitions through technological identities and their …
A Deep Learning Approach For Mapping Shrubs, Wet Tundra And Surface Water In Arctic Tundra With Very High Resolution Satellite Imagery, Darko Radakovic
A Deep Learning Approach For Mapping Shrubs, Wet Tundra And Surface Water In Arctic Tundra With Very High Resolution Satellite Imagery, Darko Radakovic
Theses, Dissertations and Culminating Projects
Arctic shrub expansion threatens to accelerate permafrost thaw through complex feedbacks, yet whether shrubs primarily indicate or drive degradation remains unresolved. This dissertation integrates deep learning analysis of two decades of satellite imagery with LiDAR canopy structure and radar soil moisture data to reveal that shrubs play a dual role: young, expanding shrubs signal active permafrost thaw, while mature, tall shrubs stabilize underlying permafrost through insulation. By demonstrating that vertical canopy structure predicts thaw depth better than cover extent alone, this work establishes a scalable framework for monitoring permafrost vulnerability across the rapidly changing Arctic. Arctic shrub expansion is accelerating …
Differential Impact Of Admission Type And Clinical Complexity On Diabetes Hospitalization Costs Among African American And Hispanic Patients In Southeastern Virginia, Ismail El Moudden, Asra Amidi, Reem Sharaf-Alddin, Michael C. Bittner, Qi Zhang
Differential Impact Of Admission Type And Clinical Complexity On Diabetes Hospitalization Costs Among African American And Hispanic Patients In Southeastern Virginia, Ismail El Moudden, Asra Amidi, Reem Sharaf-Alddin, Michael C. Bittner, Qi Zhang
Department of Obstetrics & Gynecology Faculty Publications
Background
Diabetes mellitus (DM) imposes substantial healthcare costs with documented disparities among African Americans and Hispanic patients. To inform care delivery and resource allocation, this study identified hospitalization cost predictors among African American and Hispanic patients with diabetes in Southeastern Virginia.
Methods
We analyzed 6,011 hospital discharges from the Virginia Health Information database (2016-2020) for adults aged 18-85 with diabetes. Discharges were classified by Medicare Severity Diagnosis-Related Groups: DM with complications/comorbidities (DCC, n = 3,328), DM with major complications/comorbidities (DMCC, n = 1,518), and DM without major complications/comorbidities (DWO, n = 1,165). Because cost distributions were right-skewed (skewness 3.5-8.24), we …
Consensus And Controversies Of International Guidelines For The Diagnosis, Surveillance, And Management Of Fetal Growth Restriction: An Updated Comparison, Daniele Diane Mascio, Suneet P. Chauhan, Tullio Ghi, Asma Khalil, Juliana G. Martins, Sara Sorrenti, Tamara Stampalija, Fabrizio Zullo, Francesc Figueras
Consensus And Controversies Of International Guidelines For The Diagnosis, Surveillance, And Management Of Fetal Growth Restriction: An Updated Comparison, Daniele Diane Mascio, Suneet P. Chauhan, Tullio Ghi, Asma Khalil, Juliana G. Martins, Sara Sorrenti, Tamara Stampalija, Fabrizio Zullo, Francesc Figueras
Department of Obstetrics & Gynecology Faculty Publications
OBJECTIVE: To compare areas of consensus and disagreements across contemporary international and national guidelines on the diagnosis, surveillance, and management of fetal growth restriction (FGR).
DATA SOURCES: Electronic searches of MEDLINE from database inception up to March 2026 using MeSH terms and keywords related to FGR and guidelines. STUDY ELIGIBILITY CRITERIA: Critical, structured comparison of national or international guidelines on FGR published since 2010. Final inclusion required unanimous agreement from all authors.
STUDY APPRAISAL AND SYNTHESIS METHODS: Pre-specified extraction across domains: definition; prediction/prevention; surveillance tools and frequency; delivery timing and mode; and labor induction methods. Dual data …
Preliminary Investigation Of The Carbon Storage Potential In The Fort Worth Basin: Reservoir Characterization And Modeling Of The Lower Atoka Grant South Sand In Tarrant County, Texas, Mary Ann M. Moody
Earth & Environmental Sciences Theses
Carbon capture and storage (CCS) is crucial for mitigating atmospheric carbon dioxide (CO2) emissions that rise from industrial activities. Paleozoic sedimentary basins in Texas are significant reservoirs for hydrocarbon production, and when depleted, show promise for CCS. Long-term reservoir storage suitability requires a multifaceted approach, including site screening and ranking, as well as reservoir characterization, modeling, and simulation. This project first evaluates the CCS potential for the Fort Worth Basin in North Central Texas, then focuses on reservoir characterization of the Lower Atoka Grant South (STH) Sand in Tarrant County and finally assesses the sand’s CO2 storage …
Developing Collaboration And Community Through An Online Virtual Modality: Participatory Action Research, Jennifer Reed
Developing Collaboration And Community Through An Online Virtual Modality: Participatory Action Research, Jennifer Reed
Doctor of Education Dissertations
This action research study examined educators’ perceptions of collaboration and community within a virtual professional learning community and investigated how participation influenced collaborative actions over time. The study also compared the needs and goals of secondary and postsecondary educators participating in a shared VPLC model. Grounded in the Community of Inquiry and Online Collaborative Learning theoretical frameworks, this study addressed a growing need for effective, flexible professional learning structures that support collaboration across educational contexts. Data were collected from six educators, including three secondary and three postsecondary instructors, through pre- and post-administration of the Professional Learning Community Assessment–Revised, recorded virtual …
Artificial Intelligence Adoption In The Workplace. An Exploration Of Augmentation, Oyinkansola O. Sodiya
Artificial Intelligence Adoption In The Workplace. An Exploration Of Augmentation, Oyinkansola O. Sodiya
Management Dissertations
As collaborative work with artificial intelligence (AI augmentation) gains interest, it is crucial to investigate factors that affect how employees perceive and use AI tools at work. Drawing on task-technology fit and technology adoption theories, this dissertation examines the ways in which task dimensions, organizational contexts, and individual differences affect the perceived usefulness of working with AI tools. This dissertation demonstrates that task-technology fit is fundamental. Employees in jobs with high information processing demands are likely to positively perceive the usefulness of AI augmentation relative to employees in jobs with high interpersonal demands. Employees with more proactive personalities perceive greater …
Toward Interpretable Multi-Omics Multimodal Biomedical Artificial Intelligence, Yanjun Lyu
Toward Interpretable Multi-Omics Multimodal Biomedical Artificial Intelligence, Yanjun Lyu
Computer Science and Engineering Dissertations
The complexity of human disease arises from biological processes that unfold across multiple scales, from molecular variation through cellular function, tissue organisation, brain phenotypes, each of which is associated with distinct measurement modalities, regularities, and characteristic. Contemporary biomedical artificial intelligence has brought the opportunity to reveal the complexity with in; however, its methodological default, in which models are trained on most readily available modality, does not adequately engage with the multi-scale connected structure by which biological meaning is constituted. The research area of multi-omics and multi-modal AI for biomedicine remains at an early exploratory stage, and the work presented in …
Uncertainty Quantification, Propagation & Conjunction Assessment In Orbital Mechanics Using Generalized Polynomial Chaos Expansion & 2-Dimensional Conjunction Plane Analysis Techniques, Monalisa Karim
Mechanical and Aerospace Engineering Theses
Uncertainties, that are inherent to dynamic models, can be associated with state initial conditions, force modelling errors, navigation and actuation errors. In system modelling stochastic differential equations are used to represent dynamic phenomena with uncertainties, for which the solutions are probability density functions of quantities of interest characterizing the realization of the stochastic processes. In Polynomial Chaos Expansion (PCE) propagation, these solutions are represented as weighted sums of multivariate spectral polynomials that are functions of the input random variables. Generalized polynomial chaos expansion (gPC) is an extension to the original homogenous PCE which projects the random solution onto a basis …
Flow Injection Determination Of Fluoride For Total Organic Fluorine Analysis, Memona Zulafiqar
Flow Injection Determination Of Fluoride For Total Organic Fluorine Analysis, Memona Zulafiqar
Chemistry & Biochemistry Theses
Poly- and perfluoroalkyl substances (PFAS) are anthropogenic chemicals that have gained increasing attention due to their association with a wide range of adverse health effects. These compounds are highly diverse, with approximately 15,000 PFAS reported. Their exceptional environmental stability and strong tendency to bioaccumulate result in environmentally relevant concentrations that typically occur at very low levels, often in the ng L⁻¹ range. This chemical diversity presents a major analytical challenge, as reference standards are available for only a limited number of PFAS. Consequently, conventional targeted analytical methods frequently quantify less than 1% of the total PFAS present, leading to a …
Liutex - A Fluid Vortex, Oscar Alvarez
Liutex - A Fluid Vortex, Oscar Alvarez
Mathematics Dissertations
Fluid vortices are found everywhere in our universe. A vortex can take the form of almost anything - from the classical spiral vortex to chaotic plumes. Defining a vortex physically and mathematically is absolutely necessary if we desire to study vortices and their interactions with each other as well as our physical world. Fluid vortices are incredibly important in the study of turbulent flows. From determining wear, optimizing design for better flow, efficiency, etc., to even predicting the weather on Earth or other planets, having the ability to measure vortices in fluid flow is invaluable. In this study, I investigate …
An Investigation On Downwind Impacts Of The Keweenaw Peninsula On Lake-Effect Snow Events, Thomas M. Pavell
An Investigation On Downwind Impacts Of The Keweenaw Peninsula On Lake-Effect Snow Events, Thomas M. Pavell
Dissertations, Master's Theses and Master's Reports
Lake-effect snow (LES) produces copious amounts of snow across the Great Lakes region. While mechanisms and impacts are well-understood, they remain difficult to observe and study over Lake Superior and the Upper Peninsula of Michigan due to a large gap in radar coverage and sparse in-situ measurements. The goal of this project aimed to characterize variables present across Lake Superior and counties on and downstream of the Keweenaw Peninsula that contribute to the formation and evolution of lake-effect snowbands. Nine different lake-effect snow events were analyzed in this project, identifying structures and features resulting from upstream passage over the Keweenaw …
Adaptive Control For A Robotic Bipedal Device Using A Hybrid Discrete-Continuous Reinforcement Learning Strategy, Karla Rincon-Martinez, Wen Yu, Isaac Chairez
Adaptive Control For A Robotic Bipedal Device Using A Hybrid Discrete-Continuous Reinforcement Learning Strategy, Karla Rincon-Martinez, Wen Yu, Isaac Chairez
Mathematics Faculty Publications
This research develops and implements a novel reinforcement learning (RL) architecture to address the trajectory-tracking problem in bipedal robotic systems under articulated-joint constraints. The proposed RL framework extends previously designed adaptive controllers characterized by state-dependent gain structures. The learning mechanism comprises two hierarchical adaptation layers: the first employs an adaptive dynamic programming (ADP) formulation to approximate the Bellman value function using a class of continuous-time dynamic neural networks. In contrast, the second uses an iterative optimization scheme based on the deep deterministic policy gradient (DDPG) algorithm. The resulting control strategy minimizes a robust performance index defined over the tracking trajectories …
Ablative Study Of Large Language Model-Based Gesture Inference For Autonomous Navigation, Neil Loftus
Ablative Study Of Large Language Model-Based Gesture Inference For Autonomous Navigation, Neil Loftus
Theses, Dissertations and Capstones
Human gesture inference has broad applications ranging from sign language interpretation to device control. Traditional methods often rely on extensive manually labeled hand datasets for deep learning. Furthermore, they are typically limited to a discrete set of gestures existing in these datasets. Large Language Models (LLMs) created by enterprise companies such as OpenAI have demonstrated positive results in many artificial intelligence tasks, with a notable strength being their adaptability. Existing literature has shown that LLM based systems can not only perform gesture inference but can propose user intent provided with a context and list of possible actions. We propose an …
A Conserved Ethylene-Triggered Cell Death Mechanism May Underlie Hollow Stem Formation Across Plant Species, Mengxiao Yan, Weijuan Fan, Yinghui Meng, Jiamin Zhao, Wei Yang, Ziyin Xu, Yusen Gao, Haiyan Zhuang, Wuyu Zhou, Yuqin Wang, Qingjun Huang, Ling Yuan, Hongxia Wang, Jun Yang
A Conserved Ethylene-Triggered Cell Death Mechanism May Underlie Hollow Stem Formation Across Plant Species, Mengxiao Yan, Weijuan Fan, Yinghui Meng, Jiamin Zhao, Wei Yang, Ziyin Xu, Yusen Gao, Haiyan Zhuang, Wuyu Zhou, Yuqin Wang, Qingjun Huang, Ling Yuan, Hongxia Wang, Jun Yang
Plant and Soil Sciences Faculty Publications
Hollow stems have independently evolved multiple times across the plant kingdom and play crucial roles in plant development and various environmental adaptations. However, the mechanisms underlying stem hollowness remain poorly understood. Water spinach (Ipomoea aquatica) is one of the few hollow-stemmed plants in the Convolvulaceae family (eudicot: asterid), and its hollow stems are essential for thriving in aquatic environments. Using histochemical staining and transcriptome analysis, we found that programmed cell death (PCD) is involved in cavity formation at water spinach shoot tips. Single-cell and spatial transcriptome analyses further revealed that ethylene and reactive oxygen species (ROS) likely drive …
Supplemental Bibliographic Details. From 2001 Mars Odyssey To Earth’S Climate Crisis: Integrating Gamma Spectroscopy, Martian Soil Simulants, And Plant Genomes For Agroecology, Anchored In Sri Lanka’S Mars-Context Serpentinites, Suniti Karunatillake, Maheshi Dassanayake, Carlos Gary Bicas
Supplemental Bibliographic Details. From 2001 Mars Odyssey To Earth’S Climate Crisis: Integrating Gamma Spectroscopy, Martian Soil Simulants, And Plant Genomes For Agroecology, Anchored In Sri Lanka’S Mars-Context Serpentinites, Suniti Karunatillake, Maheshi Dassanayake, Carlos Gary Bicas
Planetary Science Lab
Bibliographic details follow to supplement hyperlinked citations in the multinational GANGOTRI-supporting project conceived by Karunatillake, Dassanayake, and Gary-Bicas
Delaying Cancer Progression By Integrating Toxicity Constraints In A Model Of Adaptive Therapy, Jana L. Gevertz, Harsh Vardhan Jain, Irina Kareva, Kathleen P. Wilkie, Joel Brown, Yitong Pepper Huang, Eduardo Sontag, Vladimir Vinogradov, Mark Davies
Delaying Cancer Progression By Integrating Toxicity Constraints In A Model Of Adaptive Therapy, Jana L. Gevertz, Harsh Vardhan Jain, Irina Kareva, Kathleen P. Wilkie, Joel Brown, Yitong Pepper Huang, Eduardo Sontag, Vladimir Vinogradov, Mark Davies
Mathematics Sciences: Faculty Publications
Cancer therapies often fail when intolerable toxicity or drug-resistant cancer cells undermine otherwise effective treatment strategies. Over the past decade, adaptive therapy has emerged as a promising approach to postpone emergence of resistance by altering dose timing based on tumor burden thresholds. Despite encouraging results, these protocols often overlook the crucial role of toxicity-induced treatment breaks, which may permit tumor regrowth. Herein, we explore the following question: would incorporating toxicity feedback improve or hinder the efficacy of adaptive therapy? To address this question, we propose a mathematical framework for incorporating toxic feedback into treatment design. We and that the degree …
Investigating Ui Based And Ai Based Interactions In Vr Environments For Human Anatomy Education, Siddharth Sondhi
Investigating Ui Based And Ai Based Interactions In Vr Environments For Human Anatomy Education, Siddharth Sondhi
Master's Projects
Traditional approaches to learning and simulation often struggle to convey the complexity of three dimensional structures. In anatomy education, methods such as textbooks, lectures, and cadaver based learning are used, but can make it difficult to understand the complex structure of organs within the human body. Virtual Reality (VR) offers a promising alternative by providing immersive and interactive 3D environments that allow users to explore and manipulate anatomical structures more intuitively. These environments can be further enhanced by integrating large language models (LLMs) as intelligent agents capable of guiding users through natural language interaction. This project presents a Unity-based VR …
Improving Pid Control With Bayesian Optimization For Adversarially Robust Federated Learning, Adrian Pena, Sergei Chuprov, Raman Zatsarenko, Leon Reznik
Improving Pid Control With Bayesian Optimization For Adversarially Robust Federated Learning, Adrian Pena, Sergei Chuprov, Raman Zatsarenko, Leon Reznik
Computer Science Faculty Publications
Federated Learning (FL) often suffers from unstable convergence and reduced robustness under non-IID data and malicious attacks. In this paper, we present FedPIDAvg_tuned, a control-theoretic aggregation framework for improving stability and adversarial robustness in FL. In particular, our approach combines a server-side Proportional–Integral–Derivative (PID) controller with Bayesian optimization to tune controller gains for different data and attack conditions. The PID controller regulates global model updates through feedback on loss dynamics, providing adaptive scaling that improves stability and convergence. The tuned gains are applied within a trust-weighted trimmed-mean mechanism to remove adversarial or outlier updates. Using the Flower framework, we evaluate …