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Full-Text Articles in Physical Sciences and Mathematics

Regenerative Agriculture: A Pathway For Addressing Nebraska’S Water Quality And Soil Degradation Challenges, Kjersten Hyberger May 2023

Regenerative Agriculture: A Pathway For Addressing Nebraska’S Water Quality And Soil Degradation Challenges, Kjersten Hyberger

Department of Environmental Studies: Undergraduate Student Theses

It is important to begin this thesis by acknowledging that the State of Nebraska is on stolen Native land. Furthermore, the University of Nebraska is a land-grant university that was ultimately given 89,920 acres of Native lands for the paltry sum of $11,194. To date, the University of Nebraska has benefited from a 51:1 profit ratio on the funds raised from its 1873 land grant, raising over $500,000 in endowment principle. I humbly acknowledge that the privilege of earning my degree at UNL came through the often violent and bloody displacement of multiple tribal nations (High Country News, 2020).


Evaluating Ecosystem Health Of The Salt Creek Basin Through Two-Eyed Seeing, Shelby Serritella May 2023

Evaluating Ecosystem Health Of The Salt Creek Basin Through Two-Eyed Seeing, Shelby Serritella

Department of Environmental Studies: Undergraduate Student Theses

Few instances of prior research into socio-ecological health have brought together both Indigenous Knowledge Systems and Western science, especially in Nebraska. This study attempts to fill this gap in Lancaster County, Nebraska by using “Two-Eyed Seeing”. This equitably combines both Indigenous Knowledge Systems (qualitative data), obtained through oral interviews with Indigenous community members, and Western science (quantitative data), obtained through USGS, UNL, and U.S. Drought Monitor databases, to assess ecosystem health. Changes to the Salt Creek Basin were collected and analyzed through this Two-Eyed Seeing framework. Results found that there are high levels of consensus between both knowledge systems regarding …


Identifying A Consumer–Producer Agricultural Knowledge Gap, Aspen Rittgarn May 2023

Identifying A Consumer–Producer Agricultural Knowledge Gap, Aspen Rittgarn

Department of Environmental Studies: Undergraduate Student Theses

The purpose of this paper and online survey was to see if an agricultural knowledge gap between consumers and producers be found. Low agricultural literacy rates can lead to misconceptions of the agriculture industry, unhealthy food choices, environmentally unfriendly product choices, food waste, etc. The hypothesis for this thesis is that those born in the mid1960s to early 1980s (Generation X) will be the start of an increased knowledge gap. The survey was compiled of both qualitative and quantitative questions and questions were inspired by American Farm Bureau’s AITC Benchmarks. Responses were analyzed and the results revealed that my participants …


Listening For Common Ground In High School And Early Collegiate Mathematics, Gail Burrill, Henry Cohn, Yvonne Lai, Dev P. Sinha, Ji Y. Son, Katherine F. Stevenson May 2023

Listening For Common Ground In High School And Early Collegiate Mathematics, Gail Burrill, Henry Cohn, Yvonne Lai, Dev P. Sinha, Ji Y. Son, Katherine F. Stevenson

Department of Mathematics: Faculty Publications

Solutions to pressing and complex social challenges require that we reach for common ground. Only through cooperation among people with a broad range of backgrounds and expertise can progress be made on issues as challenging as improving student success in mathematics. In this spirit, the AMS Committee on Education held a forum in May 2022 entitled The Evolving Curriculum in High School and Early Undergraduate Mathematical Sciences Education.1 This article is a report on that forum by the authors listed above, who were among the organizers and presenters.


Leveraging Aruco Fiducial Marker System For Bridge Displacement Estimation Using Unmanned Aerial Vehicles, Mohamed Aly May 2023

Leveraging Aruco Fiducial Marker System For Bridge Displacement Estimation Using Unmanned Aerial Vehicles, Mohamed Aly

School of Computing: Dissertations, Theses, and Student Research

The use of unmanned aerial vehicles (UAVs) in construction sites has been widely growing for surveying and inspection purposes. Their mobility and agility have enabled engineers to use UAVs in Structural Health Monitoring (SHM) applications to overcome the limitations of traditional approaches that require labor-intensive installation, extended time, and long-term maintenance. One of the critical applications of SHM is measuring bridge deflections during the bridge operation period. Due to the complex remote sites of bridges, remote sensing techniques, such as camera-equipped drones, can facilitate measuring bridge deflections. This work takes a step to build a pipeline using the state-of-the-art computer …


Assessment Of Bridge Pier Response To Fire, Vehicle Impact, And Air Blast, Chen Fang, Qusai Alomari, Daniel G. Linzell May 2023

Assessment Of Bridge Pier Response To Fire, Vehicle Impact, And Air Blast, Chen Fang, Qusai Alomari, Daniel G. Linzell

Department of Civil and Environmental Engineering: Dissertations, Theses, and Student Research

Highway bridges exposed to intentional or unintentional fire followed by combined vehicle impact and air blast are at risk of significant damage and, possibly, collapse. Limited studies examining the complex effects of these extreme demands on bridge support elements and parametrizing their response and damage are found in the open literature. Research that is presented is part of an ongoing numerical investigation examining round, multi-column, reinforced concrete (RC), bridge pier behavior subject to multi-hazard scenarios involving fire, vehicle impact, and air blast. Detailed nonlinear finite element analysis models of single columns and multi-column piers supported by a pile foundation system …


Dea2uth: A Decentralized Authentication And Authorization Scheme For Secure Private Data Transfer, Phillipe Austria May 2023

Dea2uth: A Decentralized Authentication And Authorization Scheme For Secure Private Data Transfer, Phillipe Austria

UNLV Theses, Dissertations, Professional Papers, and Capstones

The sharing of private information is a daunting, multifaceted, and expensive undertaking. Furthermore, identity management is an additional challenge that poses significant technological, operational, and legal obstacles. Present solutions and their accompanying infrastructures rely on centralized models that are susceptible to hacking and can hinder data control by the rightful owner. Consequently, blockchain technology has generated interest in the fields of identity and access control. This technology is viewed as a potential solution due to its ability to offer decentralization, transparency, provenance, security, and privacy benefits. Nevertheless, a completely decentralized and private solution that enables data owners to control their …


On Outflows Due To Radiation, Randall Cody Dannen May 2023

On Outflows Due To Radiation, Randall Cody Dannen

UNLV Theses, Dissertations, Professional Papers, and Capstones

Observations of ionized AGN outflows have provided compelling evidence that the radiation field transfers both momentum and energy to the plasma. At parsec scale distances in AGN, energy transfer can dominate, in which case the only force needed to launch an outflow is due to gas pressure. Much closer to the black hole, gravity dominates thermal energy due to insufficient heating by the radiation and the gas is in the so-called ’cold wind solution’ regime. Only magnetic or radiation forces can lead to outflow, but it is unclear how these forces depend on the spectral energy distribution (SED) and the …


Outside, Looking In: A Dissertation On Mindful Walking And How Green Exercise Affects State Mindfulness And Connectedness To Nature, Dustin Wyatt Davis May 2023

Outside, Looking In: A Dissertation On Mindful Walking And How Green Exercise Affects State Mindfulness And Connectedness To Nature, Dustin Wyatt Davis

UNLV Theses, Dissertations, Professional Papers, and Capstones

INTRODUCTION: Mindfulness, green exercise, and connectedness to nature are increasingly popular topics among academics and the public. These three topics overlap in the underexplored area called mindful green exercise. Mindful green exercise is a blend of mindful exercise and green exercise. Mindful exercise is physical exercise during which people pay attention on purpose without judgment to each new present moment. The person applies an accepting awareness to internal phenomena (thoughts, emotions, and bodily sensations) and external phenomena (objects and events in the environment). Green exercise is exercise performed outdoors in natural environments. Despite its name, green exercise does not only …


Investigating Haloacetonitrile (Han) Formation Potential From Nitrogenous Antibiotics And Agrochemicals, Kazi Shafayet Haider May 2023

Investigating Haloacetonitrile (Han) Formation Potential From Nitrogenous Antibiotics And Agrochemicals, Kazi Shafayet Haider

UNLV Theses, Dissertations, Professional Papers, and Capstones

Disinfection can promote safe drinking water. Chlorine and chloramines are the two most used disinfectants. While these disinfectants are effective in inactivating disease-causing pathogens, they also produce hazardous byproducts when they react with organic compounds (precursors). Nitrogenous disinfection byproducts (N-DBPs) are more toxic than their counterparts. The increased use of nitrogen-based agrochemicals and antibitics has led to their detection in different water sources. The presence of secondary amine and aniline in these compounds can act as a source of reactive nitrogen to form N-DBPs. In addition, the increased concentration of bromide in water systems due to anthropogenic activities can enhance …


Response Of The Isothermal Mode Grüneisen Tensor Across Phase Boundaries, Jasmine K. Hinton May 2023

Response Of The Isothermal Mode Grüneisen Tensor Across Phase Boundaries, Jasmine K. Hinton

UNLV Theses, Dissertations, Professional Papers, and Capstones

The assumptions for the 1912 Grüneisen parameter are reviewed, particularly in the cases of anisotropy, high temperatures, and across phase boundaries. Two main case studies are shown: β-Sn, and Cd. The main techniques of this work involve resistively heated diamond anvil cells with both optical Raman spectroscopy and x-ray diffraction. It is found in Sn that the isothermal mode Grüneisen tensor along increasing isotherms diverges from the single-valued temperature aggregate at the onset of melt, and this is proposed to use as a method of exploring melt phase boundaries in other systems. This method is examined once again on another …


Metastability And Degradation In Cu(In,Ga)Se2 Thin-Film Solar Cells, Mohsen Jahandardoost May 2023

Metastability And Degradation In Cu(In,Ga)Se2 Thin-Film Solar Cells, Mohsen Jahandardoost

UNLV Theses, Dissertations, Professional Papers, and Capstones

Cu(In,Ga)(S,Se)2 or CIGS is a thin-film semiconductor that has shown a device efficiency of 23.35% and 24.2% for single-junction and perovskite/CIGS tandem solar cells, respectively. CIGS offers promising properties such as tunable bandgap and ease of processing making them great candidates for thin-film tandem devices. However, knowledge of the effect of material defects, buffer materials, and post-deposition treatment (PDT) on degradation and metastability behavior in these devices is not well understood.In this dissertation, metastability and long-term degradation of CIGS thin-film solar cells have been investigated under combinatorial stress factors of heat, light, and voltage bias to systematically understand the effect …


Solving Boundary Value And Initial Boundary Value Problems Of Partial Differential Equations Using Meshless Methods, Adam Johnson May 2023

Solving Boundary Value And Initial Boundary Value Problems Of Partial Differential Equations Using Meshless Methods, Adam Johnson

UNLV Theses, Dissertations, Professional Papers, and Capstones

In this dissertation, the methods of fundamental solutions (MFS) and the methods of particular solutions (MPS) are used to solve the boundary value problems of the Poisson and Helmholtz equations, where the particular solutions of the Poisson and Helmholtz equations in [13, 14] are used. Then the initial boundary value problems of the diffusion and wave equations are discretized into a sequence of boundary value problems of the Helmholtz equation by using either the Laplace transform or time difference methods along the lines of [8]. The Helmholtz problems are solved consequently in an iterative manner which leads to the solution …


Exploration Of H2o Ice At Extreme Conditions, Zachary M. Grande May 2023

Exploration Of H2o Ice At Extreme Conditions, Zachary M. Grande

UNLV Theses, Dissertations, Professional Papers, and Capstones

Static compression experiments on water ice are needed for precise characterization and discovery of new ice phases near room temperature. Here I present my efforts and the developments that have been made to reduce detrimental effects found in high-pressure experiments in order to acquire precise measurements on ice approaching 3 Mbar. Several key observations are made, relating to the phase transition of ice-VII to X, an intermediate phase I have named ice-VIIt and evidence of a post ice X phase. Some of these experiments have been replicated using D2O ice as well, in order to gain insight into nuclear quantum …


Study Of Trace Elements In Southern Nevada Spring Waters And Lakes, Hyejeong Lee May 2023

Study Of Trace Elements In Southern Nevada Spring Waters And Lakes, Hyejeong Lee

UNLV Theses, Dissertations, Professional Papers, and Capstones

Comprehending the natural water resource is imperative for the entire state of Nevada and of particular significance for Southern Nevada, where rapid population growth and climate change are placing significant strain on supplies. This research underscores the significance of water chemistry in identifying potential water source areas through trace elements. For the first time, the study proposed measuring the compositions of the entire suite of metal elements, ranging from Li to U, in over 40 springs in the Moapa Valley and its upper gradient valleys, utilizing the iCAP Qc ICP-MS (Inductively Coupled Plasma Mass Spectrometer) at UNLV. The research evaluated …


Critical Metals: From Granitic Pegmatites To The Anthropogenic Cycle, Dalton Mccaffrey May 2023

Critical Metals: From Granitic Pegmatites To The Anthropogenic Cycle, Dalton Mccaffrey

UNLV Theses, Dissertations, Professional Papers, and Capstones

Critical metals are vital to the functionality of the modern world. The increased diversity and usage intensity of these commodities in defense-related and strategic technologies (e.g., jet engines, rocket assemblies), modern infrastructure and products (e.g., high-strength steel, cellular phones, laptop computers), and energy-related, low-emissions technologies (e.g., nuclear reactors, solar panels, wind turbines, hybrid and electric vehicles) has drastically increased our reliance on critical metals and, thus, the United States (and global) exposure to supply restrictions. Granitic pegmatites are unique mineral deposits that represent a past, present and future resource for many (approximately half) of these critical resources. Even with the …


Enhanced Iot-Based Electrocardiogram Monitoring System With Deep Learning, Jian Ni May 2023

Enhanced Iot-Based Electrocardiogram Monitoring System With Deep Learning, Jian Ni

UNLV Theses, Dissertations, Professional Papers, and Capstones

Due to the rapid development of computing and sensing technologies, Internet of Things (IoT)-based cardiac monitoring plays a crucial role in providing patients with cost-efficient solutions for long-term, continuous, and pervasive electrocardiogram (ECG) monitoring outside a hospital setting. In a typical IoT-based ECG monitoring system, ECG signals are picked up by sensors located on the edge, and then uploaded to the remote cloud servers. ECG interpretation is performed for the collected ECGs in the cloud servers and the analysis results can be made instantly available to the patients as well as their healthcare providers.In this dissertation, we first examine the …


A One-Dimensional Analysis Of A Microbial Fuel Cell For Efficient Acetate Removal And Power Density Output, David Rouhani May 2023

A One-Dimensional Analysis Of A Microbial Fuel Cell For Efficient Acetate Removal And Power Density Output, David Rouhani

UNLV Theses, Dissertations, Professional Papers, and Capstones

Microbial fuel cells (MFCs) are electrochemical devices that utilize microorganisms to convert organic matter into electrical energy. MFCs have been discussed to have potential application for sustainable wastewater treatment due to their ability to generate electricity while simultaneously treating contaminated water. To optimize MFC performance, numerical models can be used to understand the complex electrochemical and biological processes occurring in the system. In this study, a numerical model was developed to simulate the performance of MFCs under varying operating conditions and to investigate the performance of a MFC for treating wastewater fuel. More specifically, the MFC was modeled to oxidize …


A Machine Learning Approach To Evaluate The Effect Of Sodium-Glucose Cotransporter-2 Inhibitors On Chronic Kidney Disease In Diabetes Patients, Solomon Eshun May 2023

A Machine Learning Approach To Evaluate The Effect Of Sodium-Glucose Cotransporter-2 Inhibitors On Chronic Kidney Disease In Diabetes Patients, Solomon Eshun

Theses and Dissertations

Chronic kidney disease (CKD) is a significant complication that contributes to diabetes-related mortality in the United States, and there is growing evidence that sodium-glucose cotransporter 2 inhibitors (SGLT2i) can slow its progression. However, observational studies may suffer from confounding by indication, where patient characteristics and disease severity influence the decision to prescribe SGLT2i. This study utilized electronic health records of individuals with diabetes (from TriNetX) to investigate the effectiveness of SGLT2i on CKD progression. The database provided detailed information on patients’ CKD status, demographics, diagnosis, procedures, and medications, along with corresponding dates of diagnosis and prescription. The study comprised of …


Congruences For Quotients Of Rogers-Ramanujan Functions, Maria Del Rosario Valencia Arevalo May 2023

Congruences For Quotients Of Rogers-Ramanujan Functions, Maria Del Rosario Valencia Arevalo

Theses and Dissertations

In 1919 the mathematician Srinivasa Ramanujan conjectured congruences for the partition function p(n) modulo powers of the primes 5,7,11. In this work, we study Ramanujan type congruences modulo powers of primes p = 7,11,13,17,19,23 satisfied by the Fourier coefficients of quotients the Rogers-Ramanujan Functions G(τ) and H(τ) and the Dedekind eta function η(5τ). In addition to deriving new congruences, we develop the foundational theory of modular forms to motivate and prove the results. The work includes proofs of congruences facilitated by Python/SageMath code.


Hydroclimate Effects On Great Salt Lake Decline Since 1980, Siiri Joy Bigalke May 2023

Hydroclimate Effects On Great Salt Lake Decline Since 1980, Siiri Joy Bigalke

All Graduate Plan B and other Reports, Spring 1920 to Spring 2023

As a terminal basin lake, the Great Salt Lake (GSL) is known to act as a barometer for low frequency climate variability for the Western United States. As thus, there are naturally occurring large changes to GSL elevation levels that vary on time scales from years to decades. However, amongst these naturally occurring interannual changes there has been a significant declining trend in the elevation levels since a string of anomalous pluvial years in the early 1980s. In the summer of 2022, the Great Salt Lake reached its lowest levels in recorded history, which coincided with a two-decades long regional …


Re-Evaluating Natural Intelligence In The Face Of Chatgpt, Elvin T. Lim, Tze K Koh May 2023

Re-Evaluating Natural Intelligence In The Face Of Chatgpt, Elvin T. Lim, Tze K Koh

Research Collection College of Integrative Studies

How will new technologies impact the nature of higher education? Before ChatGPT, the world witnessed major shifts led by innovations in information storage and transmission. Papyrus in ancient Egypt, the Gutenberg press in 15th-century Europe, and the internet in the 20th century were all milestones in the mass dissemination of knowledge.


Assessment Of Phytoplankton Assemblages And Harmful Algal Blooms In New Jersey, Yaritza Acosta Caraballo May 2023

Assessment Of Phytoplankton Assemblages And Harmful Algal Blooms In New Jersey, Yaritza Acosta Caraballo

Theses, Dissertations and Culminating Projects

Urbanization, industrialization, and climate change have played a major role in the pollution of waterways, leading to a global increasing trend of harmful algal blooms (HAB) while jeopardizing water quality. Phytoplankton and HAB were evaluated within the highly urbanized and historically polluted state of New Jersey to help provide statewide baseline data for HAB and water quality management. A total of three studies were included in this dissertation. In the first study, phytoplankton communities were characterized in freshwaters of New Jersey during the cyanobacterial HAB season and their relationships to water quality at both statewide and ecoregion levels were examined. …


Seasonal Variations In Nutrient And Total Suspended Solids Sources And Fluxes In Rivers Of Northern New Jersey And Newark Bay, Usa, Jing Nie May 2023

Seasonal Variations In Nutrient And Total Suspended Solids Sources And Fluxes In Rivers Of Northern New Jersey And Newark Bay, Usa, Jing Nie

Theses, Dissertations and Culminating Projects

In recent decades, aquatic systems have experienced major problems with water quality due to high nutrient concentrations from both point and non-point sources resulting from industrialization, urbanization, and population growth. While nutrient pollution due to land use change cannot be ignored, point sources such as combined sewer overflows and discharging sites have also contributed to the problem. Integrated hydrodynamic, chemical, and biological models have been developed to simulate nutrient transportation from both sources. This paper reviews and analyzes water quality data from published literature to evaluate nutrient pollution in aquatic systems and emphasizes the need for a continuously developed integrated …


The Fate Of Fraxinus Spp. In New Jersey : A Physioeconomic Evaluation Of The Forest System And Infrastructure Implications, Erik W. Lyttek May 2023

The Fate Of Fraxinus Spp. In New Jersey : A Physioeconomic Evaluation Of The Forest System And Infrastructure Implications, Erik W. Lyttek

Theses, Dissertations and Culminating Projects

Though the impacts of pest infestation on forested ecosystems vary, the natural factors that facilitate outbreaks are of concern across multiple disciplines across the USA, affecting such diverse fields as economics, ecology, hydrology, atmospheric sciences, and pedology. Emerald Ash Borer (EAB) is a typical example of an aggressive invasive forest pest; it has proven difficult to eliminate, resistant to natural predators, and damaging to local flora. EAB has recently proliferated through the northern and mid-western forests of the USA, devastating the native population of ash trees (Fraxinus spp.), and has invaded an estimated 28% of all susceptible trees. In New …


Antarctic Peninsula Ice Sheet Dynamics In The Pliocene From Sedimentological Interpretation Of Ocean Drilling Program Site 1097, Ridley Joseph May 2023

Antarctic Peninsula Ice Sheet Dynamics In The Pliocene From Sedimentological Interpretation Of Ocean Drilling Program Site 1097, Ridley Joseph

Theses, Dissertations and Culminating Projects

Studying ice sheet behavior during the Pliocene Epoch is of great importance. The Early Pliocene was characterized by warm climatic conditions, similar carbon dioxide levels and high sea levels compared to the present. This time frame provides essential information on the foreseeable future of Earth’s cryosphere, particularly if climate change continues to persist. The sedimentary record of the Antarctic Peninsula Ice Sheet (APIS) is the focus of this study. At Ocean Drilling Program (ODP) Site 1097, cores were drilled into Pliocene strata at a shallow depth on the Antarctic Peninsula continental shelf. Sedimentary facies were interpreted, and twenty samples were …


Parameter Optimization For Excitable Cell Models, Amrit Parmar May 2023

Parameter Optimization For Excitable Cell Models, Amrit Parmar

Theses, Dissertations and Culminating Projects

The electrophysiology of nodose ganglia neurons is of great interest in the analysis of cell membrane currents and action potential behavior. This behavior was initially outlined in the Hodgkin-Huxley conductance model [1] using a system of nonlinear differential equations. Later, Schild et al. [2] developed an extension of the Hodgkin-Huxley model to provide a more exhaustive description of ion channels involved in nodose neuronal action potential activity. We consider a variety of methods to fit the parameters of both the Hodgkin-Huxley and Schild et al. models to an empirical stimulus response dataset. Our methods were validated using synthetic datasets, as …


Potential Of Increased Thermal Tolerance As A Response To Acute Heat Stress In A Disease-Transmitting Mosquito Species, Nicole Ashley Scanlon May 2023

Potential Of Increased Thermal Tolerance As A Response To Acute Heat Stress In A Disease-Transmitting Mosquito Species, Nicole Ashley Scanlon

Theses, Dissertations and Culminating Projects

Each year hundreds of millions of people are infected with mosquito-borne illnesses. West Nile Virus is the leading cause of mosquito-borne diseases in the United States (McDonald et al., 2021). The first case of West Nile Virus was detected in the United States in 1999 (Sejvar, 2003). Since that time the number of cases has dramatically risen. Mosquitoes are ectotherms which means their body temperature is dependent on the thermal conditions outside of their body. Because of this they are very sensitive to changes in their environment. The Earth’s average temperature has been slowly but steadily rising. This small but …


The Identification Of Rogue Access Points Using Channel State Information, Irene Mcginniss May 2023

The Identification Of Rogue Access Points Using Channel State Information, Irene Mcginniss

Theses, Dissertations and Culminating Projects

Today's wireless networks (Wi-Fi) handle more significant numbers of connections, deploy efficiently, and provide increased reliability and high speeds at low cost. The ability of rogue access points (RAPs) to mimic legitimate APs makes them the most critical threat to wireless security. APs are found in coffee shops, supermarkets, stadiums, buses, trains, airports, hospitals, theaters, and shopping malls.

Rogue access points (RAP) are unauthorized devices that connect to legitimate access points and networks and bypass authorized security procedures. RAP detection has been attempted using hardware and software-based solutions requiring the developing of dedicated tools or beacon frame modification. (Arisandi, 2021). …


The Interconnected Roles Of Residues N189, E168, And S220 In M. Tuberculosis Indole-3-Glycerol Phosphate Synthase Catalysis, Erik Domlija May 2023

The Interconnected Roles Of Residues N189, E168, And S220 In M. Tuberculosis Indole-3-Glycerol Phosphate Synthase Catalysis, Erik Domlija

Theses, Dissertations and Culminating Projects

Tuberculosis (TB) is an infectious disease caused by the bacteria Mycobacterium tuberculosis that primarily attacks the lungs. Drug resistance for M. tuberculosis is emerging and therefore new drug targets need to be identified. One way to target TB is through the inhibition of the tryptophan biosynthetic pathway of M. tuberculosis since production of tryptophan is essential for the replication of M. tuberculosis. The enzyme Indole-3-glycerol phosphate synthase (MtIGPS) was chosen as a potential drug target due to its role in tryptophan biosynthesis. Residue N189 interacts with active site residues E168 and S220. It is inferred from previous studies done with …