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Articles 37741 - 37770 of 294419

Full-Text Articles in Physical Sciences and Mathematics

The Qomolangma Station For Atmospheric And Environmental Observation And Research, Chinese Academy Of Sciences, Institute Of Tibetan Plateau Research Chinese Academy Of Sciences Oct 2023

The Qomolangma Station For Atmospheric And Environmental Observation And Research, Chinese Academy Of Sciences, Institute Of Tibetan Plateau Research Chinese Academy Of Sciences

Bulletin of Chinese Academy of Sciences (Chinese Version)

No abstract provided.

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Strengthening Ecological Protection And Green Development In Pearl River Basin To Support Construction Of Guangdong-Hong Kong-Macao Greater Bay Area, Bojie Fu, Guangqing Huang, Hong'ou Zhang, Junze Zhang Oct 2023

Strengthening Ecological Protection And Green Development In Pearl River Basin To Support Construction Of Guangdong-Hong Kong-Macao Greater Bay Area, Bojie Fu, Guangqing Huang, Hong'ou Zhang, Junze Zhang

Bulletin of Chinese Academy of Sciences (Chinese Version)

The Pearl River is the largest river flowing into the South China Sea in China. The unique natural environmental characteristics and geographical location make the Pearl River Basin (PRB) rich in natural resources and huge development potential, and it has an important strategic position in the construction of China’s ecological security system and national economic development planning. At present, the upper and middle reaches of the PRB consist of crucial part of China’s strategic pattern of ecological security, and the lower reach is the Guangdong-Hong Kong-Macao Greater Bay Area. However, influenced by multiple factors such as regional resource endowment and …

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Decentralized Science (Desci): A New Paradigm For Diverse And Sustainable Scientific Development, Feiyue Wang, Wenwen Ding Oct 2023

Decentralized Science (Desci): A New Paradigm For Diverse And Sustainable Scientific Development, Feiyue Wang, Wenwen Ding

Bulletin of Chinese Academy of Sciences (Chinese Version)

The rise of artificial intelligence for science (AI4S) has made it particularly important and urgent to ensure the openness, fairness, impartiality, diversity, and sustainability of scientific systems. This is significant to the discourse power and leadership of countries in global innovation and industrial revolution, and also affects the security, stability, and sustainable development of a community with a shared future for mankind. To address these challenges, AI4S needs to adopt new scientific organizational and operational methods. Decentralized science (DeSci) has emerged to vitalize AI4S and provide strong support, effectively addressing issues such as information silos, biases, unfair distribution, and monopolies …

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Ten-Year Review And Outlook For International Science Program—Integrated Research On Disaster Risk (Irdr), Huadong Guo, Fang Chen, Qunli Han, Jie Liu Oct 2023

Ten-Year Review And Outlook For International Science Program—Integrated Research On Disaster Risk (Irdr), Huadong Guo, Fang Chen, Qunli Han, Jie Liu

Bulletin of Chinese Academy of Sciences (Chinese Version)

Integrated Research on Disaster Risk (IRDR) Program is a 10-year international science program initiated by International Council of Scientific Unions (ICSU), International Social Sciences Council (ISSC), and United Nations Office International Strategy for Disaster Reduction (UNISDR). In 2009, International Programme Office (IPO) of IRDR Program successfully applied by China Association for Science and Technology in Beijing, became the first office of ICSU Interdisciplinary Body hosted in Asia. IRDR Program has been implemented for ten years, and it has become the flagship program for global integrated research on disaster risk, established an extensive global disaster risk comprehensive research network, and formed …

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Hydrogen Peroxide-Dependent Oxidation Of Erk2 Within Its D-Recruitment Site Alters Its Substrate Selection, Anthony E. Postiglione, Laquaundra L. Adams, Ese S. Ekhator, Anuoluwapo E. Odelade, Supriya Patwardhan, Meenal Chaudhari, Avery S. Pardue, Anjali Kumari, William A. Lefever, Olivia P. Tornow, Tamer S. Kaoud, Johnathan Neiswinger, Jun Seop Jeong, Derek Parsonage, Kimberly J. Nelson, Dukka Kc, Cristina M. Furdui, Heng Zhu, Andrew J. Wommack, Kevin N. Dalby, Ming Dong, Leslie B. Poole, Jeremiah D. Keyes, Robert H. Newman Oct 2023

Hydrogen Peroxide-Dependent Oxidation Of Erk2 Within Its D-Recruitment Site Alters Its Substrate Selection, Anthony E. Postiglione, Laquaundra L. Adams, Ese S. Ekhator, Anuoluwapo E. Odelade, Supriya Patwardhan, Meenal Chaudhari, Avery S. Pardue, Anjali Kumari, William A. Lefever, Olivia P. Tornow, Tamer S. Kaoud, Johnathan Neiswinger, Jun Seop Jeong, Derek Parsonage, Kimberly J. Nelson, Dukka Kc, Cristina M. Furdui, Heng Zhu, Andrew J. Wommack, Kevin N. Dalby, Ming Dong, Leslie B. Poole, Jeremiah D. Keyes, Robert H. Newman

Michigan Tech Publications

Extracellular signal-regulated kinases 1 and 2 (ERK1/2) are dysregulated in many pervasive diseases. Recently, we discovered that ERK1/2 is oxidized by signal-generated hydrogen peroxide in various cell types. Since the putative sites of oxidation lie within or near ERK1/2’s ligand-binding surfaces, we investigated how oxidation of ERK2 regulates interactions with the model substrates Sub-D and Sub-F. These studies revealed that ERK2 undergoes sulfenylation at C159 on its D-recruitment site surface and that this modification modulates ERK2 activity differentially between substrates. Integrated biochemical, computational, and mutational analyses suggest a plausible mechanism for peroxide-dependent changes in ERK2-substrate interactions. Interestingly, oxidation decreased ERK2’s …

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Determining The Ideal Concentrations Of Ethanol And Propylene Glycol In Ethosomes For Transdermal Delivery Of Vitamin D3, Rebecca Conner Oct 2023

Determining The Ideal Concentrations Of Ethanol And Propylene Glycol In Ethosomes For Transdermal Delivery Of Vitamin D3, Rebecca Conner

Harrisburg University Research Symposium: Highlighting Research, Innovation, & Creativity

Vitamin D3 is an important chemical in the human body, however, many Americans have low levels of this vitamin. There are plenty of oral supplementations for Vitamin D3 deficiency, but those of older age and busy schedules may struggle to meet the minimum requirement. A recently developed ethosomal transmembrane delivery system (Touitou, 2000), similar to liposomes but also containing ethanol, allows users to apply a gel dermally and have the desired drug or active ingredient reach the bloodstream faster. However, there is considerable variation in the concentration of ethanol and permeation enhancers used. Using an affordable method to …

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Would You Choose The Same Nationality If You Were Born Again?, Keito Kono, Logan Bowerman Oct 2023

Would You Choose The Same Nationality If You Were Born Again?, Keito Kono, Logan Bowerman

Harrisburg University Research Symposium: Highlighting Research, Innovation, & Creativity

Nationality is an important element in the formation of identity, but this brings up a question; that is whether people are proud of their nationality. Thus, we decided to investigate how many people would prefer to have the same nationality if they were born again. This survey is important because it could provide an opportunity to recognize people's interest in other countries and their patriotism

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Most Popular Genre's Of Videogames To Play For Hu Students, Asheria Upsher, Jean Orejuela, Joshua Scott Oct 2023

Most Popular Genre's Of Videogames To Play For Hu Students, Asheria Upsher, Jean Orejuela, Joshua Scott

Harrisburg University Research Symposium: Highlighting Research, Innovation, & Creativity

Our Poster will show the most played and favored videogame genre's according to HU students.

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The Relationship Between Pets Owned And Gender Amongst College Students, Eman Asghar, Bryce Camuso, Josh Feirick Oct 2023

The Relationship Between Pets Owned And Gender Amongst College Students, Eman Asghar, Bryce Camuso, Josh Feirick

Harrisburg University Research Symposium: Highlighting Research, Innovation, & Creativity

There is a gap between the number of men and women that own dogs. The Mintel Press Team states that "71% of men aged 18-44 own a dog compared to 60% of their female counterparts" (Mintel Press Team, 2016, para: 1). While this statistic includes people who are college-aged, it does not mention college students specifically. Thus, research into the relationship between pets owned and gender amongst college students is an important topic that warrants looking into.

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Habit-Tracking Application For Individuals With Attention Deficit Hyperactivity Disorder (Adhd), Hannah Wishon Oct 2023

Habit-Tracking Application For Individuals With Attention Deficit Hyperactivity Disorder (Adhd), Hannah Wishon

Harrisburg University Research Symposium: Highlighting Research, Innovation, & Creativity

This project aims to create a habit-tracking app that would cater to the needs of those with ADHD while being accessible enough to be used by the general, neurotypical public.

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The Knowledge Of One's Blood Type, Mackenzie Degroft, Ethan Hall, Scarlet Morillo Oct 2023

The Knowledge Of One's Blood Type, Mackenzie Degroft, Ethan Hall, Scarlet Morillo

Harrisburg University Research Symposium: Highlighting Research, Innovation, & Creativity

An experiment of sample surveys of undergraduate students' knowledge of their blood type.

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A Statistical Study Into The Number Of Hours Students At Harrisburg University Spend On Social Media, Nabeel Hakeem-Olowu, Samantha Weaver, Kyla Lea Oct 2023

A Statistical Study Into The Number Of Hours Students At Harrisburg University Spend On Social Media, Nabeel Hakeem-Olowu, Samantha Weaver, Kyla Lea

Harrisburg University Research Symposium: Highlighting Research, Innovation, & Creativity

The aim of the study is to examine the number of hours that Harrisburg University students spent on social media during their spare time. The purpose of the study is to raise awareness among students about the possible negative impacts of excessive social media usage on their academic performance, social interactions, and sleep duration. Additionally, the study explored the relationship between social media use and academic performance. To collect data, we surveyed one hundred and fifty students from Harrisburg University. The survey consisted of questions related to the number of hours spent on social media during spare time. The respondents …

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Roguelike Development, Luke Speicher Oct 2023

Roguelike Development, Luke Speicher

Harrisburg University Research Symposium: Highlighting Research, Innovation, & Creativity

I started the process of Game Development on an arena-based roguelike game, using the Construct 3 engine for the development. This included documents with the design process timeline, as well as design documents for content within the game.

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Metaverse Key Requirements And Platforms Survey, Akbobek Abilkaiyrkyzy, Ahmed Elhagry, Fedwa Laamarti, Abdulmotaleb El Saddik Oct 2023

Metaverse Key Requirements And Platforms Survey, Akbobek Abilkaiyrkyzy, Ahmed Elhagry, Fedwa Laamarti, Abdulmotaleb El Saddik

Computer Vision Faculty Publications

The growing interest in the metaverse has led to an abundance of platforms, each with its own unique features and limitations. This paper's objective is two-fold. First, we aim at providing an objective analysis of requirements that need to be fulfilled by metaverse platforms. We survey a broad set of criteria including interoperability, immersiveness, persistence, multimodal and social interaction, scalability, level of openness, configurability, market access, security, and blockchain integration, among others. Second, we review a wide range of existing metaverse platforms, and we critically evaluate their ability to meet the requirements listed. We identify their limitations, which must be …

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Is Math Real? How Simple Questions Lead Us To Mathematics' Deepest Truths, Eugenia Cheng Oct 2023

Is Math Real? How Simple Questions Lead Us To Mathematics' Deepest Truths, Eugenia Cheng

Dalrymple Lecture Series

Where does math come from: from rules in a textbook? From logic and deduction? Not quite. In this talk Eugenia Cheng will argue that math comes from human curiosity - most importantly, from asking questions. Many people are discouraged from asking these questions in school, thinking they’re too simple to be taken seriously, or being told that their questions are stupid. But often, these simple-sounding questions lead to wondrous mathematical revelations. Dr Cheng will take us on a journey of discovery starting with questions like "Why does 2x3 = 3x2?" and "What's the point of maths?", leading us into research-level …

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Observed Increases In North Atlantic Tropical Cyclone Peak Intensification Rates, Andra J. Garner Oct 2023

Observed Increases In North Atlantic Tropical Cyclone Peak Intensification Rates, Andra J. Garner

School of Earth & Environment Departmental Research

Quickly intensifying tropical cyclones (TCs) are exceptionally hazardous for Atlantic coastlines. An analysis of observed maximum changes in wind speed for Atlantic TCs from 1971 to 2020 indicates that TC intensification rates have already changed as anthropogenic greenhouse gas emissions have warmed the planet and oceans. Mean maximum TC intensification rates are up to 28.7% greater in a modern era (2001–2020) compared to a historical era (1971–1990). In the modern era, it is about as likely for TCs to intensify by at least 50 kts in 24 h, and more likely for TCs to intensify by at least 20 kts …

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3-Dimensional Quartic Bézier Curve Approximation Model By Using Neutrosophic Approach, Siti Nur Idara Rosli, Mohammad Izat Emir Zulkifly Oct 2023

3-Dimensional Quartic Bézier Curve Approximation Model By Using Neutrosophic Approach, Siti Nur Idara Rosli, Mohammad Izat Emir Zulkifly

Neutrosophic Systems with Applications

In a 3-dimensional data collection process, there exists noise data that cannot be included to visualize the process. Therefore, it is difficult to deal with since fuzzy set and intuitionistic fuzzy set theories did not consider the indeterminacy problem. However, using a neutrosophic approach with three memberships: truth, false, and indeterminacy membership function, the error data will be treated as uncertain data by using the indeterminacy degree. Thus, this study will visualize the 3-dimensional quartic Bézier curve model by using neutrosophic set theory. To construct the model, the neutrosophic quartic control point must first be introduced to approximate the neutrosophic …

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2023 October 19 - Tennessee Weekly Drought Summary, Tennessee Climate Office, East Tennessee State University Oct 2023

2023 October 19 - Tennessee Weekly Drought Summary, Tennessee Climate Office, East Tennessee State University

Tennessee Climate Office Weekly Drought Summaries

No abstract provided.

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Structural Design And Synthesis Of Growth Factor Receptor Binding Protein 2 (Grb2) Stabilizing Small Molecule, Mahfuzul Hasan Oct 2023

Structural Design And Synthesis Of Growth Factor Receptor Binding Protein 2 (Grb2) Stabilizing Small Molecule, Mahfuzul Hasan

Theses and Dissertations

The growth factor receptor tyrosine kinase (RTK) family is a potent inducer of cellular growth. Ligand binding to cognate receptors on plasma membrane induces receptor dimerization and activation, which in turn recruits intracellular molecules for downstream signal transduction. A key signaling pathway activated by growth factor (GF) receptors is the Ras signaling cascade that ultimately leads to cell proliferation. Activation of RTKs leads to the recruitment of adapter protein Grb2, which is constitutively bound to the mammalian homolog of drosophila son of sevenless (SOS), and a guanine exchange factor (GEF) for Ras. The recruitment of the Grb2-SOS complex by activated …

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3-Dimensional Quartic Bézier Curve Approximation Model By Using Neutrosophic Approach, Siti Nur Idara Rosli, Mohammad Izat Emir Zulkifly Oct 2023

3-Dimensional Quartic Bézier Curve Approximation Model By Using Neutrosophic Approach, Siti Nur Idara Rosli, Mohammad Izat Emir Zulkifly

Neutrosophic Systems with Applications

In a 3-dimensional data collection process, there exists noise data that cannot be included to visualize the process. Therefore, it is difficult to deal with since fuzzy set and intuitionistic fuzzy set theories did not consider the indeterminacy problem. However, using a neutrosophic approach with three memberships: truth, false, and indeterminacy membership function, the error data will be treated as uncertain data by using the indeterminacy degree. Thus, this study will visualize the 3-dimensional quartic Bézier curve model by using neutrosophic set theory. To construct the model, the neutrosophic quartic control point must first be introduced to approximate the neutrosophic …

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Biosynthesis Of Mgo Nanoparticles And Their Impact On The Properties Of The Pva/Gelatin Nanocomposites For Smart Food Packaging Applications, Mohamed Morsy Oct 2023

Biosynthesis Of Mgo Nanoparticles And Their Impact On The Properties Of The Pva/Gelatin Nanocomposites For Smart Food Packaging Applications, Mohamed Morsy

Nanotechnology Research Centre

No abstract provided.

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Unraveling Vibrational Spectral Signatures Of Strongly Hydrogen-Bonded Protons Via Development Of Novel Gas-Phase Ultrafast Spectroscopic Methods, Liangyi Chen Oct 2023

Unraveling Vibrational Spectral Signatures Of Strongly Hydrogen-Bonded Protons Via Development Of Novel Gas-Phase Ultrafast Spectroscopic Methods, Liangyi Chen

Arts & Sciences Graduate Student Theses and Dissertations

Proton-coupled electron transfer (PCET) is a vital process in chemical and biochemical catalysis, and it has attracted broad interest in mechanistic studies. Current research efforts, however, have focused on the electron transfer side of this process and are carried out in solution-phase systems. A series of model complexes that mimic the PCET reaction center of Tyr−His pair in Photosystem II were first synthesized and characterized in the ground-electronic state with cryogenic-ion vibrational spectroscopy (CIVS). Each model showed signatures of strong intramolecular hydrogen bonds between the PCET donor and acceptor motifs, resulting in very red shifted and diffuse OH stretch transitions. …

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Enhancing Rice Leaf Disease Classification: A Customized Convolutional Neural Network Approach, Ammar Kamal Abasi, Sharif Naser Makhadmeh, Osama Ahmad Alomari, Mohammad Tubishat, Husam Jasim Mohammed Oct 2023

Enhancing Rice Leaf Disease Classification: A Customized Convolutional Neural Network Approach, Ammar Kamal Abasi, Sharif Naser Makhadmeh, Osama Ahmad Alomari, Mohammad Tubishat, Husam Jasim Mohammed

All Works

In modern agriculture, correctly identifying rice leaf diseases is crucial for maintaining crop health and promoting sustainable food production. This study presents a detailed methodology to enhance the accuracy of rice leaf disease classification. We achieve this by employing a Convolutional Neural Network (CNN) model specifically designed for rice leaf images. The proposed method achieved an accuracy of 0.914 during the final epoch, demonstrating highly competitive performance compared to other models, with low loss and minimal overfitting. A comparison was conducted with Transfer Learning Inception-v3 and Transfer Learning EfficientNet-B2 models, and the proposed method showed superior accuracy and performance. With …

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Deciphering The Role Of Molecular Interactions On The Interfacial Structure Of Aqueous And Non-Aqueous Interfaces, Dodangodage Ishara Indunil Senadheera, D I. Senadheera Oct 2023

Deciphering The Role Of Molecular Interactions On The Interfacial Structure Of Aqueous And Non-Aqueous Interfaces, Dodangodage Ishara Indunil Senadheera, D I. Senadheera

LSU Doctoral Dissertations

The study focused on "Deciphering the role of molecular interactions on the interfacial structure of aqueous and non-aqueous interfaces" holds immense significance in diverse scientific and industrial domains. Our primary objective is to unravel the intricate web of molecular interactions occurring at the boundaries between aqueous and non-aqueous phases. The research presented here spans a wide scope, encompassing applications in microelectromechanical systems in the semiconductor industry, energy-efficient membranes for electrochemical separations, and renewable energy storage systems. Molecular dynamics simulations were conducted in collaboration with experimental studies, specifically atomic force microscopy, to achieve insights at the molecular level.The first project centered …

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Fall Town Hall On Research Data Management, Megan Hurst, Christine Madsen, Kristi Thompson Oct 2023

Fall Town Hall On Research Data Management, Megan Hurst, Christine Madsen, Kristi Thompson

Western Libraries Presentations

This Town Hall was held to share recommendations for Research Data Management at Western that result from a gap analysis to understand the RDM needs at Western, conducted by Athenaeum21, a strategy and technology consultancy engaged by Western for this work. The recommendations will inform the implementation of Western’s Research Data Management Strategy, which shapes Research Data Management at Western for all researchers, grant funded or not, student or faculty, regardless of discipline.

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Investigating The Roles Of Active Site Residues In Mycobacterium Tuberculosis Indole-3-Glycerol Phosphate Synthase, A Potential Target For Antitubercular Agents, David W. Konas, Sarah Cho, Oshane D. Thomas, Maryum M. Bhatti, Katherine Leon Hernandez, Cinthya Moran, Hedda Booter, Thomas Candela, Joseph Lacap, Paige Mcfadden, Savannah Van Den Berg, Alyssa M. Welter, Ashley Peralta, Cheryl A. Janson, Jaclyn Catalano, Nina M. Goodey Oct 2023

Investigating The Roles Of Active Site Residues In Mycobacterium Tuberculosis Indole-3-Glycerol Phosphate Synthase, A Potential Target For Antitubercular Agents, David W. Konas, Sarah Cho, Oshane D. Thomas, Maryum M. Bhatti, Katherine Leon Hernandez, Cinthya Moran, Hedda Booter, Thomas Candela, Joseph Lacap, Paige Mcfadden, Savannah Van Den Berg, Alyssa M. Welter, Ashley Peralta, Cheryl A. Janson, Jaclyn Catalano, Nina M. Goodey

Department of Chemistry and Biochemistry Faculty Scholarship and Creative Works

Mycobacterium tuberculosis drug resistance is emerging and new drug targets are needed. Tryptophan biosynthesis is necessary for M. tuberculosis replication and virulence. Indole-3-glycerol phosphate synthase (IGPS) catalyzes a step in M. tuberculosis tryptophan biosynthesis and has been suggested as a potential anti-infective target, but our understanding of this enzyme is limited. To aid in inhibitor design and gain a greater mechanistic picture of this enzyme, there is a need to understand the roles of active site amino acids in ligand binding and catalysis. In this work, we explored the roles of conserved active site amino acids Glu57, Lys59, Lys119, Glu168, …

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Epidemiologic Understanding Of The Un Sustainable Development Goals, Zeinab Baba Oct 2023

Epidemiologic Understanding Of The Un Sustainable Development Goals, Zeinab Baba

Sustainability Research & Practice Seminar Presentations

A Sustainability Research & Practice Seminar entitled "Epidemiologic Understanding of the UN Sustainable Development Goals," presented by Professor Zeinab Baba, Department of Public Health Sciences, West Chester University of Pennsylvania.

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Integrating Nist And Iso Cybersecurity Audit And Risk Assessment Frameworks Into Cameroonian Law, Bernard Ngalim Oct 2023

Integrating Nist And Iso Cybersecurity Audit And Risk Assessment Frameworks Into Cameroonian Law, Bernard Ngalim

Journal of Cybersecurity Education, Research and Practice

This paper reviews cybersecurity laws and regulations in Cameroon, focusing on cybersecurity and information security audits and risk assessments. The importance of cybersecurity risk assessment and the implementation of security controls to cure deficiencies noted during risk assessments or audits is a critical step in developing cybersecurity resilience. Cameroon's cybersecurity legal framework provides for audits but does not explicitly enumerate controls. Consequently, integrating relevant controls from the NIST frameworks and ISO Standards can improve the cybersecurity posture in Cameroon while waiting for a comprehensive revision of the legal framework. NIST and ISO are internationally recognized as best practices in information …

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Lrtransformer: Learn-Region Transformer For Object-Agnostic Point Cloud Segmentation, Dipesh Gyawali Oct 2023

Lrtransformer: Learn-Region Transformer For Object-Agnostic Point Cloud Segmentation, Dipesh Gyawali

LSU Master's Theses

3D point cloud segmentation segments the 3D point cloud data into different regions/instances depending on their features that have numerous applications in robotics, autonomous driving, digital twinning, augmented reality, etc. The majority of the existing point cloud segmentation methods depend on class labels to identify 3D objects in the surroundings. Our work focuses on segmenting point clouds into different regions/instances in an object-agnostic manner for any number of objects in the environment. Given the point cloud, our method can segment the entire scene into multiple instances without depending on object shape and size. We leverage the power of the self-attention …

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Improving Human-Automation Collaboration In Motion Planning, Torin J. Adamson Oct 2023

Improving Human-Automation Collaboration In Motion Planning, Torin J. Adamson

Computer Science ETDs

Human-automation collaboration is becoming a part of everyday life as AI helps us drive, make decisions, and solve a variety of other tasks. However, safe and effective collaboration systems depend on factors in trust, communication, and more. Existing studies to explore these are typically carried out in laboratory settings, providing robust data under tight environmental control. However, human behavior evolves over time, driven by external factors that cannot be fully captured in single participation sessions. These factors form the "human context", contextualizing the behavioral data for a more complete understanding. In this thesis, video game adaptations upon conventional subject studies …

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