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Articles 32311 - 32340 of 294413

Full-Text Articles in Physical Sciences and Mathematics

Tillering Of ‘Marandu’ Brachiaria Under Different Nitrogen Rates In The Brazilian Savannah, A. B. O. Assis, A. L. Bocchi, T. C. Pedrosa, A. O. Matos, A. P. B. Soares Jan 2024

Tillering Of ‘Marandu’ Brachiaria Under Different Nitrogen Rates In The Brazilian Savannah, A. B. O. Assis, A. L. Bocchi, T. C. Pedrosa, A. O. Matos, A. P. B. Soares

IGC Proceedings (1977-2023)

The tiller is the basic unit of grass growth and tiller density determines the horizontal ground cover, leaves production and pastures perennially. The objective in this study was to quantify the number of aerial and basal tillers and basal:aerial tillers ratio in Urochloa brizantha cv. Marandu, established in Brazilian savannah, submitted to nitrogen doses (0, 50, 100 and 150 kg N/ha). The experiment was carried out in the Forage and Pasture Sector of Jataí Federal University (UFJ) and after soil correction and fertilization, plots were established with Marandu palisade grass in a randomized block design, with four replications and four …


Effect Of Soil Source And Variety On The Heavy Metal Contents Of Guinea Grass, C. C. Anotaenwere, P. O. Bankole, P. A. Dele, Alaba O. Jolaosho Jan 2024

Effect Of Soil Source And Variety On The Heavy Metal Contents Of Guinea Grass, C. C. Anotaenwere, P. O. Bankole, P. A. Dele, Alaba O. Jolaosho

IGC Proceedings (1977-2023)

The aim of this study was to evaluate the heavy metal content in soils and grasses planted on selected contaminated soils. The study was a 3 x 2 factorial experiment in a completely randomized design comprising of two factors which are: 3 soil sources (i.e., industrial site, dump site and Fadama (a lowland around a river/stream) which was used as the control) and 2 varieties of Megathyrsus maximus (var. Local and Ntchisi) replicated four times. Soils were collected from the three sites and planting was done in a greenhouse. Soil samples were collected before and after planting. Samples of the …


Effect Of Nitrogen Source And Age At Harvest On The In Vitro Digestibility Of Oba Super Ii Maize Fodder, C. C. Anotaenwere, P. A. Dele, F. E. Salawu, B. T. Akinyemi, O. A. Okukenu, Alaba O. Jolaosho Jan 2024

Effect Of Nitrogen Source And Age At Harvest On The In Vitro Digestibility Of Oba Super Ii Maize Fodder, C. C. Anotaenwere, P. A. Dele, F. E. Salawu, B. T. Akinyemi, O. A. Okukenu, Alaba O. Jolaosho

IGC Proceedings (1977-2023)

This experiment was carried out in the Pasture Section of the Directorate of University farms and the laboratory of Department of Pasture and Range Management, Federal University of Agriculture, Abeokuta, Nigeria, to evaluate the effect of nitrogen source (Swine manure, N.P.K. 15:15:15 as well as the control) and age at harvest on the in vitro gas production and digestibility of Oba Super II maize fodder. The experiment was in a split plot design. The nitrogen source was applied at the rate of 120 kgN/ha two weeks after planting. Maize was harvested at 8, 10 and 12 weeks after planting, oven …


Harvest Time Determine Biomass And Nutritive Value Of Forage Soybean In The Northwestern Loess Plateau Of China, An Dong, Jean Marie Vianney Nsigayehe, Y. Y. Shen Jan 2024

Harvest Time Determine Biomass And Nutritive Value Of Forage Soybean In The Northwestern Loess Plateau Of China, An Dong, Jean Marie Vianney Nsigayehe, Y. Y. Shen

IGC Proceedings (1977-2023)

Soybean is a critical legume crop, which can be used as high protein forage in a crop-forage rotation system to supplement forage and increase system productivity. According to the actual production demand, selecting a suitable harvest time and the best feeding variety of soybean can provide a theoretical basis for applying forage soybean in a rotation system. In this study, four forage soybean varieties were selected in the Loess Plateau of northwest China. They were harvested on three dates suitable for local rotation conditions, and their biomass and nutritive value were evaluated. At the early harvest (20 August), the nutritive …


Developing A Simple Bioassay For Detection Of Alfalfa Autotoxicity In Field Soils, P. Baisley, K. Cassida, S. Gruss, E. Hill Jan 2024

Developing A Simple Bioassay For Detection Of Alfalfa Autotoxicity In Field Soils, P. Baisley, K. Cassida, S. Gruss, E. Hill

IGC Proceedings (1977-2023)

Alfalfa autotoxicity causes yield reductions in alfalfa production by inhibiting plant establishment and decreasing plant productivity. Accurate predictions regarding autotoxic potential of the soil in a given field at a given time are an essential tool for alfalfa growers to make appropriate planting decisions. To address this issue, we are developing a soil bioassay that can be conducted as a mail-in soil test for alfalfa growers through plant diagnostic service laboratories. We hypothesize that we will detect differences in seed germination, emergence, root length, and root morphology between control and autotoxic soils. A preliminary trial testing alfalfa field soils and …


Phyllochron And Growth Dynamic Of Lolium Perenne L. And Bromus Valdivianus Phil. As Affected By Soil Ph, Phosphorus And Nitrogen Restriction, Oscar A. Balocchi, M. F. Alonso, I. Calvache Jan 2024

Phyllochron And Growth Dynamic Of Lolium Perenne L. And Bromus Valdivianus Phil. As Affected By Soil Ph, Phosphorus And Nitrogen Restriction, Oscar A. Balocchi, M. F. Alonso, I. Calvache

IGC Proceedings (1977-2023)

Permanent grasslands are the main food for livestock production systems in Southern Chile. Therefore, it is essential to develop management tools that optimize the use of pastures. Among these tools, the phyllochron could be a better method to control grazing frequency. The aim of this study was to determine the effect of three levels of soil pH, phosphorus (P) and nitrogen (N) on the phyllochron and growth dynamic of Lolium perenne and Bromus valdivianus. Nine monophytic mini-swards of each species were established in 125 L containers for three different pH, P and N levels. For one year we measured: …


Mass Production And Morphology Of Marandu Brachiaria Under Different Nitrogen Rates In The Brazilian Savannah, V. L. Banys, A. O. Matos, A. L. Bocchi, I. I. Silva, L. V. D. Ribeiro Jan 2024

Mass Production And Morphology Of Marandu Brachiaria Under Different Nitrogen Rates In The Brazilian Savannah, V. L. Banys, A. O. Matos, A. L. Bocchi, I. I. Silva, L. V. D. Ribeiro

IGC Proceedings (1977-2023)

Nitrogen is the nutrient that most contributes to increase forage productivity and quality. The objective was to evaluate Marandu brachiaria submitted to nitrogen doses in the Brazilian savannah through the total and green mass production, leaf:stem and brachiaria:weed ratio. Plots were established in a randomized block design, with four replications and four N doses 0, 50, 100 and 150 kg N/ha). After the uniformization cut, the data collect cycles occurred when the canopy reached 30 cm average height. Samples were taken until 15 cm from the ground in an area of 0.25 m2. Fractions were separated according botanical …


Grazing Management For Alfalfa Persistence And Productivity In Warm-Climate Regions, D. Basigalup Jan 2024

Grazing Management For Alfalfa Persistence And Productivity In Warm-Climate Regions, D. Basigalup

IGC Proceedings (1977-2023)

Alfalfa is the most important cultivated forage crop in Argentina, where about 3 million hectares are grown. Even though the use of direct grazing is coming down during the last 15 years, it is still important for both beef and dairy production. Alfalfa grazing can play an important role in reducing operative costs and decreasing quality loss due to forage conservation (hay or silage). In this paper, the main concepts necessary to implement adequate and practical rotational grazing systems are briefly discussed. Particular attention is given to issues such as grazing frequency, grazing period, pasture use efficiency, and alfalfa quality …


Genetic Improvement Of Bermudagrass For Hay Producers, W. F. Anderson, L. Baxter, R. N. Gates, E. Rios Jan 2024

Genetic Improvement Of Bermudagrass For Hay Producers, W. F. Anderson, L. Baxter, R. N. Gates, E. Rios

IGC Proceedings (1977-2023)

Bermudagrass (Cynodon spp.) is considered the most valuable warm-season perennial grass for hay producers in the Southeastern United States. Bermudagrass genotypes have overall good forage quality, high yields, and store well. However, there are challenges to producing good hay for the market. First, early green-up in the spring is needed to allow for four to five productive clippings during the summer. When first establishing production fields, quick emergence and cover are important for reducing weeds. Forage bermudagrass is somewhat tolerant to drought, however, low rainfall substantially reduces yields. If rainfall is too abundant, it is difficult to have timely …


Genetic Variability Of Lucerne Landraces From Central Italy Detected By Rapd Markers, L Russi, G Barcaccia, M Falcinelli, F Veronesi Jan 2024

Genetic Variability Of Lucerne Landraces From Central Italy Detected By Rapd Markers, L Russi, G Barcaccia, M Falcinelli, F Veronesi

IGC Proceedings (1977-2023)

With the aim to characterize six lucerne landraces (Medicago sativa L.), representing a sample of a collection from central Italy, sixty individuals per landrace were evaluated by screening for RAPD markers with three lucerne-specific primers. Twenty-one amplification products were scored as present or absent across all plants. The dendrogram from mean genetic similarity estimates displayed Casalina alone and the other landraces clustered into one distinct group, showing a single branch point with more than 73% of genetic similarity. The discriminant analysis grouped the landraces in a similar manner. The first function maximally separated the group Grosseto, Gubbio and C. …


Amphicarpic Legumes For Tropical Pasture Persistence, R Schultze-Kraft, A Schmidt, H Hohn Jan 2024

Amphicarpic Legumes For Tropical Pasture Persistence, R Schultze-Kraft, A Schmidt, H Hohn

IGC Proceedings (1977-2023)

Amphicarpy, by which a plant produces underground seeds in addition to aerial fruits, is found in many plant families and in species of at least 15 legume genera. First studies on the tropical Centrosema rotundifolium and subtropical Macroptilium panduratum revealed for both species, besides their stoloniferous growth habit, two important mechanisms for survival under unfavorable conditions: (1) Underground meristems and reserve organs, and (2) regeneration from a soil seed reserve based on underground, aerial-flowering independent, seed production. Underground seed production was for both species particularly high on very sandy soils, but amphicarpy enables the plants to exhibit a plasticity response …


Sensitivity Analysis Of Prior Distributions In Regression Model Estimation, Ayoade I Adewole, Oluwatoyin K. Bodunwa Jan 2024

Sensitivity Analysis Of Prior Distributions In Regression Model Estimation, Ayoade I Adewole, Oluwatoyin K. Bodunwa

Al-Bahir

Bayesian inferences depend solely on specification and accuracy of likelihoods and prior distributions of the observed data. The research delved into Bayesian estimation method of regression models to reduce the impact of some of the problems, posed by convectional method of estimating regression models, such as handling complex models, availability of small sample sizes and inclusion of background information in the estimation procedure. Posterior distributions are based on prior distributions and the data accuracy, which is the fundamental principles of Bayesian statistics to produce accurate final model estimates. Sensitivity analysis is an essential part of mathematical model validation in obtaining …


A Coupled Model Of Population, Poaching, And Economic Dynamics To Assess Rhino Conservation Through Legal Trade, Henry Doyle, Kylie Champagne, Ditto Rajpal, Grace Seebeck, David J. Gerberry Jan 2024

A Coupled Model Of Population, Poaching, And Economic Dynamics To Assess Rhino Conservation Through Legal Trade, Henry Doyle, Kylie Champagne, Ditto Rajpal, Grace Seebeck, David J. Gerberry

Spora: A Journal of Biomathematics

Rhinoceros populations in Africa are in peril largely due to the high value of their horns and the poaching that ensues. The strategy of legalizing the international trade of rhino horn is receiving increased support among both the people and government officials in Africa. Many in the international conservation community remain opposed to the idea. The legalization strategy is straightforward in theory: legalizing the trade of rhino horn will introduce a large quantity of horn to the market, the increased supply will lead to lower prices for rhino horn, and lower prices will reduce the overall poaching pressure these animals …


Yolov8-Cab: Improved Yolov8 For Real-Time Object Detection, Moahaimen Talib, Ahmed H. Y. Al-Noori, Jameelah Suad Jan 2024

Yolov8-Cab: Improved Yolov8 For Real-Time Object Detection, Moahaimen Talib, Ahmed H. Y. Al-Noori, Jameelah Suad

Karbala International Journal of Modern Science

This study presents a groundbreaking approach to enhance the accuracy of the YOLOv8 model in object detection, focusing mainly on addressing the limitations of detecting objects in varied image types, particularly for small objects. The proposed strategy of this work incorporates the Context Attention Block (CAB) to effectively locate and identify small objects in images. Furthermore, the proposed work improves the feature extraction capability without increasing model complexity by increasing the thickness of the Coarse-to-Fine(C2F) block. In addition, Spatial Attention (SA) has been modified to accelerate detection performance. The enhanced YOLOv8 model (Namely YOLOv8-CAB) strongly emphasizes the performance of detecting …


Literature Review Nature-Based Art Therapy Exploring Connections And Relationships, Janell Lopez-Curtis Jan 2024

Literature Review Nature-Based Art Therapy Exploring Connections And Relationships, Janell Lopez-Curtis

Expressive Therapies Capstone Theses

Art therapy is a modality used in clinical psychotherapy. It is supported through both quantitative and qualitative research. Branching out from art therapy is nature-based art therapy. This branch of expressive therapies holds the potential to be beneficial as art therapy due to the interconnected access to the scientific fields of ecology, ecopsychology, art therapy, expressive therapies, and other nature-based therapeutic activities; this includes intersectionality in ecological theories such as ecofeminism and deep ecology as well. Through an exploration of literature, this paper will provide definitions and theory-based support through reviewing clinical psychotherapy, evidence-based practices, and art therapy theories. The …


2024 Residential Metals Abatement Program (Rmap) Field Sampling Plan (Fsp) – Indoor Dust – Kennedy Elementary Surface Dust Resampling, Environmental Resource Management (Erm) Jan 2024

2024 Residential Metals Abatement Program (Rmap) Field Sampling Plan (Fsp) – Indoor Dust – Kennedy Elementary Surface Dust Resampling, Environmental Resource Management (Erm)

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.


Development Of Stochastic And Time-Dependent Quantum Chemical Methods For Accurate Description Of Light-Matter Interactions With Applications In Photoionization And Inverse Photoemission In Nanomaterials, Nicole Spanedda Jan 2024

Development Of Stochastic And Time-Dependent Quantum Chemical Methods For Accurate Description Of Light-Matter Interactions With Applications In Photoionization And Inverse Photoemission In Nanomaterials, Nicole Spanedda

Dissertations - ALL

There are three main focuses of this work. First, the theoretical details of the Stratified Stochastic Enumeration of Molecular Orbitals (SSE-MO) method is presented, along with its application for calculating ionization potentials (IPs) of quantum dots. The SSE-MO method can readily be applied for the purpose of efficiently and accurately calculating ionization potentials, by constructing the frequency-dependent self-energy operator and then subsequently, solving the associated Dyson equation. Constructing the frequency-dependent self-energy operator is challenging because the scaling of the computational cost with respect to system size, becomes prohibitive for large systems, such as quantum dots. This is due to the …


Synthetic Studies On Ship Modulators, Hif-2Α Antagonists, And New Rhodium Carboxylate Catalysts, Angela Pacherille Jan 2024

Synthetic Studies On Ship Modulators, Hif-2Α Antagonists, And New Rhodium Carboxylate Catalysts, Angela Pacherille

Dissertations - ALL

The PI3K pathway is a major cell signaling axis in eukaryotic cells. This pathway employs the second messenger, inositol phospholipid PI(3,4,5)P3, which is responsible for activating Akt and other kinases creating a cascade of signals. The enzyme, SH2-containing inositol-5’-phosphatase (SHIP), plays a key role in this pathway by maintaining the delicate balance of PI(3,4,5)P3. Modulation of SHIP activity through the use of small molecule inhibitors may be utilized for the treatment of certain types of cancer, Alzheimer’s disease, and diabetes. A high-throughput screen identified the small molecule SHIP1 inhibitor, NSC23922, a mixture of 3α- and 3β-aminocholestane. These diastereomers were synthesized …


Characterizing Biogenic Mnox Produced By Pseudomonas Putida Mnb1 And Its Catalytic Activity Towards Water Oxidation, Elisa Morales, Lauren N. Formankski, Sarah E. Shaner, Kari Stone Jan 2024

Characterizing Biogenic Mnox Produced By Pseudomonas Putida Mnb1 And Its Catalytic Activity Towards Water Oxidation, Elisa Morales, Lauren N. Formankski, Sarah E. Shaner, Kari Stone

Chemistry Department Faculty Articles

Mn-oxidizing microorganisms oxidize environmental Mn(II), producing Mn(IV) oxides. Pseudomonas putida MnB1 is a widely studied organism for the oxidation of manganese(II) to manganese( IV) by a multi-copper oxidase. The biogenic manganese oxides (BMOs) produced by MnB1 and similar organisms have unique properties compared to non-biological manganese oxides. Along with an amorphous, poorly crystalline structure, previous studies have indicated that BMOs have high surface areas and high reactivities. It is also known that abiotic Mn oxides promote oxidation of organics and have been studied for their water oxidation catalytic function. MnB1 was grown and maintained and subsequently transferred to culturing media …


2024 Residential Metals Abatement Program (Rmap) Field Sampling Plan (Fsp) – Indoor Dust – Kennedy Elementary Surface Dust Resampling, Environmental Resource Management (Erm) Jan 2024

2024 Residential Metals Abatement Program (Rmap) Field Sampling Plan (Fsp) – Indoor Dust – Kennedy Elementary Surface Dust Resampling, Environmental Resource Management (Erm)

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.


Auslander-Reiten Triangles On A Bounded Derived Category Of Constructible Complexes, Vishnu Prasad Sivaprasad Jan 2024

Auslander-Reiten Triangles On A Bounded Derived Category Of Constructible Complexes, Vishnu Prasad Sivaprasad

LSU Doctoral Dissertations

In this dissertation, concepts from homological algebra are used to study the existence of Auslander-Reiten triangles.

Auslander-Reiten triangles are closely related to representable functors, and the main theorem characterizes the existence of representable functors in a specific bounded derived category of constructible complexes.

Under certain boundedness conditions, a specific bounded derived category is shown to have Auslander-Reiten triangles.


Crack-Ers (Crack Riddles Applying Cybersecurity Knowledge - Escape Room Scenario), Benjamin Acuff Jan 2024

Crack-Ers (Crack Riddles Applying Cybersecurity Knowledge - Escape Room Scenario), Benjamin Acuff

Posters-at-the-Capitol

CRACK-ERS (Crack Riddles Applying Cybersecurity Knowledge - Escape Room Scenario) is a unique, beginner's level CTF game with riddle-based challenges on various cybersecurity topics. The game is driven by an adventure story-based escape room format. Existing literature indicates that traditional CTFs pose challenges for beginners with no cybersecurity background. The novelty of CRACK-ERS lies in its non-traditional design as an unplugged CTF with an adventure scenario-driven script, encouraging participants to solve cybersecurity-related riddles. CRACK-ERS targets beginner-level learners, fostering teamwork, explorative research, cybersecurity problem-solving, and riddle-cracking skills. Prior cybersecurity educational research notes limited instances of escape room-style CTF games and fewer …


Virgin Coconut Oil (Vco) Supplementation Relieves Symptoms And Inflammation Among Covid-19 Positive Adults: A Single-Blind Randomized Trial, Imelda Angeles-Agdeppa, Jacus S. Nacis, Fabian M. Dayrit, Keith V. Tanda Jan 2024

Virgin Coconut Oil (Vco) Supplementation Relieves Symptoms And Inflammation Among Covid-19 Positive Adults: A Single-Blind Randomized Trial, Imelda Angeles-Agdeppa, Jacus S. Nacis, Fabian M. Dayrit, Keith V. Tanda

Chemistry Faculty Publications

A clinical study conducted in 2020 showed that virgin coconut oil (VCO) has been found effective in the rapid relief of COVID-19 symptoms and normalization of the C-reactive protein (CRP) concentration among probable and suspected cases of COVID-19. This present study aimed to validate those results and to evaluate the effects of VCO among COVID-19 patients through a 28-day randomized, single-blind trial conducted among 76 SARS-CoV-2 RT-PCR (reverse transcription-polymerase chain report)-confirmed adults, with VCO given as a COVID-19 adjunct therapy. The results showed that VCO recipients were free from symptoms and had normal CRP concentrations by day 14. In comparison, …


Surface Modification Of Poly(4,4'-Oxydiphenilene Pyromellitimide) With Low-Pressure Plasma Treatment, Cihan Aktas Jan 2024

Surface Modification Of Poly(4,4'-Oxydiphenilene Pyromellitimide) With Low-Pressure Plasma Treatment, Cihan Aktas

USF Tampa Graduate Theses and Dissertations

This study explores the change of the wetting characteristics of commercially availablepolyimide (PI), Kapton® HN, films a type of poly(4,4′-oxydiphenylene-pyromellitimide), following treatment with low-pressure plasmas of carbon tetrafluoride (CF4), air, hydrogen (H2), carbon-dioxide (CO2) and oxygen (O2) gases as well as the surface texturing via laser-exposure procedure. The water contact angle (CA) and surface free energy (SFE) of untreated PI films were determined as 82.4°±0.8 and 45.0±0.3 mN/m, respectively. After CF4 plasma gas treatment, the CA value of PI films increased to 110.2°±1.0, while it decreased to 9.3°±2.3 after O2 plasma gas treatment. The surface free energy (SFE) of PI …


The Effect Of Exposure To Lentinula Edodes And Flammulina Velutipes On The Biodegradation Of Crystallized Polylactic Acid, Iraine Taine Jan 2024

The Effect Of Exposure To Lentinula Edodes And Flammulina Velutipes On The Biodegradation Of Crystallized Polylactic Acid, Iraine Taine

Journal of the South Carolina Academy of Science

Crystallized polylactic acid (CPLA) is a prevalent bioplastic which, despite being biodegradable, is extremely resistant to decomposition in natural environments. As a result, CPLA waste contamination is rapidly becoming a prevalent issue. Lentinula edodes and Flammulina velutipes are two widespread white-rot fungi whose capabilities for bioplastic degradation have not been examined. This study aimed to determine a natural approach for reducing plastic waste by evaluating the ability of L. edodes and F. velutipes to degrade CPLA bioplastic. It was hypothesized that CPLA samples would decrease in mass when individually treated with L. edodes and F. velutipes due to their similarities …


Quaternary Rare-Earth Oxyselenides Re4ga2se7o2 (Re = Pr, Nd) With Trigonal Bipyramidal Gase5 Units: Evaluation Of Optical, Thermoelectric, And Electrocatalytic Properties, Vidyanshu Mishra, Ibrahim Munkaila Abdullahi, Dundappa Mumbaraddi, Mohammed Jomaa, Louis Guérin, Manashi Nath, Arthur Mar Jan 2024

Quaternary Rare-Earth Oxyselenides Re4ga2se7o2 (Re = Pr, Nd) With Trigonal Bipyramidal Gase5 Units: Evaluation Of Optical, Thermoelectric, And Electrocatalytic Properties, Vidyanshu Mishra, Ibrahim Munkaila Abdullahi, Dundappa Mumbaraddi, Mohammed Jomaa, Louis Guérin, Manashi Nath, Arthur Mar

Chemistry Faculty Research & Creative Works

Phase-pure samples and single crystals of the rare-earth oxyselenides RE4Ga2Se7O2 (RE = Pr, Nd) were prepared by reactions at 950 °C. They adopt a new structure type (orthorhombic, space group Pnma, a = 11.721(2)-11.683(2) Å, b = 3.9882(7)-3.9667(7) Å, c = 29.644(5)-29.581(5) Å, Z = 4) consisting of RESe6 trigonal prisms, GaSe4 tetrahedra, and GaSe5 trigonal bipyramids linked to form corrugated layers between which strips of edge-sharing RE4O tetrahedra are inserted. The bonding character is mostly ionic within RE-O and RE-Se blocks but mostly covalent with Ga-Se blocks, …


Biochemical And Structural Analysis Of The Bacterial Enzyme Succinyl-Diaminopimelate Desuccinylase (Dape) From Acinetobacter Baumannii, Emma H. Kelley, George Minasov, Katherine Konczak, Ludmilla Shuvalova, Joseph S. Brunzelle, Shantanu Shukla, Megan Beulke, Teerana Thabthimthong, Ken W. Olsen, Nicole L. Inniss, Karla Jf Satchell, Daniel P. Becker Ph.D. Jan 2024

Biochemical And Structural Analysis Of The Bacterial Enzyme Succinyl-Diaminopimelate Desuccinylase (Dape) From Acinetobacter Baumannii, Emma H. Kelley, George Minasov, Katherine Konczak, Ludmilla Shuvalova, Joseph S. Brunzelle, Shantanu Shukla, Megan Beulke, Teerana Thabthimthong, Ken W. Olsen, Nicole L. Inniss, Karla Jf Satchell, Daniel P. Becker Ph.D.

Chemistry: Faculty Publications and Other Works

There is an urgent need for new antibiotics given the rise of antibiotic resistance, and succinyl-diaminopimelate desuccinylase (DapE, E.C. 3.5.1.18) has emerged as a promising bacterial enzyme target. DapE from Haemophilus influenzae (HiDapE) has been studied and inhibitors identified, but it is essential to explore DapE from different species to assess selective versus broad-spectrum therapeutics. We have determined the structure of DapE from the ESKAPE pathogen Acinetobacter baumannii (AbDapE) and studied inhibition by known inhibitors of HiDapE. AbDapE is inhibited by captopril and sulfate comparable to HiDapE, but AbDapE was not significantly …


Table Of Contents Jan 2024

Table Of Contents

Journal of the South Carolina Academy of Science

No abstract provided.


Htra1 Prevents And Reverses Α-Synuclein Aggregation, Rendering It Non-Toxic And Seeding Incompetent, Sheng Chen Jan 2024

Htra1 Prevents And Reverses Α-Synuclein Aggregation, Rendering It Non-Toxic And Seeding Incompetent, Sheng Chen

Arts & Sciences Graduate Student Theses and Dissertations

Protein misfolding and accumulation of misfolded species are associated with multiple neurodegenerative diseases, including Parkinson’s disease (PD), amyotrophic lateral sclerosis (ALS), and frontotemporal dementia (FTD). α-Synuclein (α-Syn) misfolding and accumulation into Lewy bodies is closely linked to Parkinson’s disease. In ALS and FTD, TDP-43 and FUS are found to be aggregated in disease pathology. These proteins aggregate and associate with both a toxic gain of function of misfolded form and a loss of function due to misfolding. Therefore, it is critical to understand molecular mechanisms by which cells can prevent protein misfolding and how the cell can reverse the aggregation …


Impact Of Type Of K Fertilizer On Dcad Of Fen Grassland In Northeast Germany, A. Behrendt, J. Pickert, F. Eulenstein, B. Kroschewski Jan 2024

Impact Of Type Of K Fertilizer On Dcad Of Fen Grassland In Northeast Germany, A. Behrendt, J. Pickert, F. Eulenstein, B. Kroschewski

IGC Proceedings (1977-2023)

A lower DCAD is required in the diet fed during the prepartum period, but increasing the DCAD of diets fed during lactation increased milk yield and dry matter intake (Overton 2020). We conducted 3 cutting date/type of fertilizer trials, harvested with 5, 4 and 3 cuts per year over 3 years. Compared to the chloride based K fertilizer, the application of a sulphate based K fertilizer did not change dry matter yield and fodder quality (NEL-, XP-content) but led to significant higher DCAD in the grass in cut 1 - 3 of all trials over 3 years. The increase of …