Physical Sciences and Mathematics Commons^™

Problem-Based Learning And Artificial Intelligence, Varna Taranikanti, Srineil Vuthaluru

Books and Book Chapters

In the current digital era, significant advancements in Artificial Intelligence (AI) have influenced various fields worldwide, particularly within the health professional education sector. This progress has also percolated into the medical education system, where Problem-Based Learning (PBL) is routinely used as a key pedagogical strategy. In PBL, students are able to fully exert their exploratory skills by solve problems through a student-centered learning approach. PBL also fosters critical thinking and encourages self-directed learning through the inquiry of clinical case scenarios. This chapter investigates the integration of AI, specifically tools like ChatGPT, into PBL frameworks to enhance learning outcomes for medical …

A Spine-Specific Lexicon For The Sentiment Analysis Of Interviews With Adult Spinal Deformity Patients Correlate With Sf-36, Sf-36, And Odi Scores: A Pilot Study Of 25 Patients, Ross Gore, Michael M. Safaee, Christopher J. Lynch, Christopher P. Ames

VMASC Publications

Classic health-related quality of life (HRQOL) metrics are cumbersome, time-intensive, and subject to biases based on the patient’s native language, educational level, and cultural values. Natural language processing (NLP) converts text into quantitative metrics. Sentiment analysis enables subject matter experts to construct domain-specific lexicons that assign a value of either negative (−1) or positive (1) to certain words. The growth of telehealth provides opportunities to apply sentiment analysis to transcripts of adult spinal deformity patients’ visits to derive a novel and less biased HRQOL metric. In this study, we demonstrate the feasibility of constructing a spine-specific lexicon for sentiment analysis …

Are We Ready For Synchronous Conceptual Modeling In Augmented Reality? A Usability Study On Causal Maps With Hololens 2, Anish Shrestha, Philippe J. Giabbanelli

VMASC Publications

(1) Background: Participatory modeling requires combining individual views to create a shared conceptual model. While remote collaboration tools have enabled synchronous online modeling, they are limited to desktop settings. Augmented reality (AR) offers a new approach by potentially providing the sense of presence found in physical collaboration, which may better support participants in achieving the sense of presence found in physical locations, thus supporting them in negotiating meaning and building a shared model. (2) Methods: Building on prior works that developed technology, we performed a usability study with pairs of modelers to examine their ability at performing key conceptual modeling …

The Relationship Between Pillar[5]Arene And Pillar[6]Arene In The Synthetic Route To A Water-Soluble Pillar[6]Arene: A Case Of Kinetic And Thermodynamic Products Or Two Distinct, Competing Reactions, Helice A. Gillis

Open Access Dissertations

Pillar[n]arenes, discovered in 2008, have already made their mark as a formidable addition to the field of supramolecular chemistry, largely due to their host-guest chemistry. While the synthesis of pillar[5]arene is well established, the synthesis of pillar[6]arene, with its larger core, has not been so straightforward and mainly accomplished through the use of bulky solvents. Here we present an optimized method for a reproducible, acid-catalyzed synthesis for a brominated pillar[6]arene, starting with a brominated monomer and using chloroform as the templating solvent. Our studies have demonstrated the ratio of brominated pillar[6]arene to brominated pillar[5]arene increases with both decreasing concentration of …

Quantifying Links Between Phytoplankton Physiology And The Environment, Gabrielle M. Armin

Open Access Dissertations

Phytoplankton are microscopic, primary producers in aquatic ecosystems worldwide. They are key links in global biogeochemical cycles, converting inorganic compounds into bioavailable nutrients which fuel fisheries. Through photosynthesis, phytoplankton play an essential role in the carbon cycle and marine biological pump, drawing carbon from the atmosphere, which is eventually sequestered in the oceans, regulating our Earth’s climate. Due to their influential role in large scale processes, there have been many efforts to characterize and quantify phytoplankton impacts to ecosystem health and global nutrient cycles. Often, phytoplankton physiology has been highly simplified in global or ecosystem models, limiting their representation to …

Light, Symbiosis, And The Biology Of Corals, Taylor R. Lindsay

Open Access Dissertations

Light is critical for the survival of most shallow water scleractinian corals. Corals are mixotrophs, acquiring energy via both feeding on water column plankton and photosynthesis via a symbiotic relationship with dinoflagellates living within their tissues. Corals rely heavily on photosynthetically derived metabolites through this symbiotic relationship, intrinsically linking their biology to light availability. Corals are known to modulate their biology to maximize light capture. However, there is a limited understanding of the interaction between morphology, physiology, and energetic strategy, as well as how light may affect these relationships. In Chapter 1, we quantified the morphology, physiology and energetic …

Development Of A Scituate Reservoir Mitigation Model For Assessing Flood Control During Extreme Scenarios, Supria Paul

Open Access Dissertations

Effective reservoir management is essential for mitigating downstream flooding, especially with the increasing frequency and intensity of extreme weather events impacting major drinking water reservoirs such as the Scituate Reservoir in Rhode Island. These reservoirs provide water for large populations but can be overwhelmed by intense precipitation, flooding and land cover changes. Climate change is expected to increase precipitation in the study area located in New England, highlighting the need for improved reservoir systems, especially given the aging dams and higher risk of failures. Additionally, land cover changes, like the widespread defoliation caused by the Gypsy Moth infestations, affect water …

Impacts Of Multiple Coastal Stressors Across Life-History Stages In The Eastern Oyster, Amaelia Zyck

Open Access Dissertations

Urbanized estuaries are characterized as a complex of biotic and abiotic stressors, which currently challenge marine life and are expected to intensify and become increasingly unpredictable under the ongoing impacts of climate change. The persistence of coastal species that inhabit these stressful environments will ultimately depend on their ability to adapt. Many of these species have complex life cycles, featuring distinct morphological and physiological developmental stages that can exhibit unique responses to environmental pressures. However, since all stages share the same genome, selective pressures acting on one stage can have cascading effects throughout the life cycle. The larval stage, being …

Probing Biomolecular Structure And Dynamics Via Infrared Action Spectroscopy, Madeline Schultz

Open Access Dissertations

Biomolecular structure is supported by a network of inter- and intramolecular interactions, which can be inherently complex in the condensed phase. Isolating biomolecules from the condensed phase to vacuum, via electrospray ionization (ESI), can afford precise control over experimental conditions, yielding additional structural insight. However, the loss of solvation inherent to the ESI process can drive structural rearrangement, particularly at charge sites.

Microsolvation reagents can be used to partially mimic the solvation of charged moieties in solution as they are brought into the gas phase through complexation. This serves two primary functions: 1) reducing propensity for structural rearrangement of systems …

Novel Methodology And Proof-Of-Concept For Proton Ct Using Spot Profile Rather Than Bragg Peak Location, Brett Albert Ruben

Open Access Dissertations

Proton radiation therapy offers a highly precise method for cancer treatment, theoretically providing superior dose deposition characteristics compared to conventional X-ray radiation therapy. Its steep and finite dose fall-off region allows for superior tumor coverage while reducing, though not eliminating, dose to surrounding healthy tissue. However, its full potential is limited by range uncertainties, particularly those arising from the reliance on X-ray-based imaging methods called computed tomography (CT) for proton-based treatment. CT image Hounsfield Units (HU) must be converted to stopping power ratios (SPR) as these ratios are the clinically relevant value for accurately planning particle interactions during proton therapy. …

Characterization Of Methodological Variability In Compound Specific Isotope Analysis Of Amino Acids (Csia-Aa), Audreyana Brown-Nash

Open Access Dissertations

The use of isotopes in the natural sciences stems from the principle that chemical reactions predictably alter the isotopic composition of a given sample. Recent advances in compound specific isotope analysis of amino acids (CSIA-AA) have paved the way for studies of increasingly complex ecological relationships, including the identification and characterization of organismal physiology, consumer-resource linkages, biogeochemical cycling, and movement ecology. The analytical power of CSIA-AA has caused an exponential increase in the number of application-based studies since its inception in the 1990s. With the technique constantly evolving to accommodate new research goals, it is important to understand how variation …

Confronting The Seaport Resilience Gap: Incentives, Frameworks, And Case Studies For Enhancing Resilience To Natural Hazards In Port Planning And Policy, Rosemarie Fusco

Open Access Dissertations

This dissertation investigates the critical issue of seaport resilience, focusing on the gaps in resilience planning and the role of incentives in motivating resilience investment. The research arc addresses the question: What incentivizes seaports to increase natural hazard resilience (NHR)? It is organized into three interconnected manuscripts, each examining distinct aspects of the problem.

The first manuscript critically examines the resilience planning approaches of Small Island Developing States (SIDS) as outlined in their National Adaptation Plans (NAPs), highlighting the limited consideration of seaports despite their critical role in economic and social connectivity. SIDS offer critical insight into seaport resilience due …

Essays On Human Decisions Related To Water Quality Problems In The United States, Sonia M. Refulio Coronado

Open Access Dissertations

Water pollution remains a pervasive and inequitable environmental threat in the United States, with mounting evidence that its burdens - whether in recreational or drinking water contexts - are unevenly distributed across communities. Urbanization, aging infrastructure, and industrial contamination have degraded both coastal waters and drinking water systems, posing serious public health and welfare concerns. At the same time, the extent to which water quality influences behavioral decisions, such as beach recreation or household adoption of water filters, remains poorly understood. Although drinking water pollution is widely ranked as a top environmental concern in national surveys, public knowledge of specific …

Beyond The Phonon Gas Model (Pgm): Unraveling The Unique Mechanistic Processes Dictating Thermal Transport In Highly Anharmonic And Disordered Materials, Sandip Thakur

Open Access Dissertations

Thermal transport in nonmetallic solids has traditionally been described by the phonon gas model (PGM), in which heat is carried by weakly interacting phonon quasiparticles in an ordered crystalline lattice. However, this model breaks down in materials characterized by strong anharmonicity, dynamic disorder, or structural complexity, features prevalent in many next-generation materials used in energy conversion, optoelectronics, and thermal management. This dissertation investigates thermal transport in such complex materials, including metal halide perovskites (MHPs), covalent organic frameworks (COFs), metal organic frameworks (MOFs), and 2D-3D heterostructures, through large-scale molecular dynamics (MD) simulations and frequency-resolved spectral analyses.

In MHPs, the work reveals …

A Socio-Ecological Investigation Of Ulithian Spearfishing, Joshua Pi

Open Access Dissertations

Coral reef socio-ecological systems (SESs) characterize the interconnected relationships between coral reef ecosystems and reef-dependent communities. One such SES exists in Ulithi Atoll, Federated States of Micronesia, where Ulithians fish, steward, and govern their reefs through customary marine tenure, traditional ecological knowledge, and cultural taboos. In recent decades, rapid modernization in Ulithi has introduced new fishing technologies, transformed fishing practices, and ultimately reshaped the functioning of Ulithi’s traditional SES. One significant change was the introduction of spearfishing during the mid-20^th century, which is more selective and individualistic compared to other community-centric fishing methods that have existed for generations. This …

Incorporating Time-Varying Parameters And Climate Drivers Into Fisheries Models, Rachel Catherine Marshall

Open Access Dissertations

Commercial fishing is a highly valuable industry in the United States and globally, and as such, managing based on the best available science is necessary to maintain important fish stocks. Some parameters in stock assessment models that are assumed to be constant over age and time may actually vary to an extent that stock assessment modeling results could be improved by allowing the parameters to vary in the models. In the present dissertation, two stock assessment parameters that are typically held constant are explored for potential time or age variance. Potential environmental drivers of nonstationary parameters are also explored. Productivity, …

Coupled Numerical Modeling Of Wave-Current Interactions In Tropical Cyclones, Angelos Papandreou

Open Access Dissertations

This Ph.D. dissertation presents a numerical modeling study of wave-current interactions in tropical cyclones. Chapter 1 focuses on wave-current interaction in shallow water during hurricane landfall, when strong winds often generate severe storm surges that dramatically raise water levels and cause significant damage to human lives and property. Large waves generated by these winds further amplify storm surges, making it necessary to couple storm surge models with wave prediction models. Currently, two-dimensional coupled storm surge-wave models incorporate the effect of waves on the storm surge through the forcing of radiation stress gradients. However, recent studies on wave-current interactions indicate that …

A Multispectral Analysis Of High Redshift Quasars And Their Energy Production Mechanisms, Erik Carlson

Open Access Dissertations

We present a complete sample of radio-loud (P_3.0 GHz = 10^27.26 W/Hz) high-redshift (z ≥ 2.5) quasars in the Northern Hemisphere (δ ≥ 0). Each source was imaged with a user-defined imaging protocol developed for the Very Large Array Sky Survey. Higher-resolution images were generated from archival observations and new Enhanced Very Large Array observations (Project Code: 24B-010).  We produced 407 images of galaxies, where we are likely the first humans to see them. Twenty of these sources were high-redshift jets which increased the number of known high-redshift jets by 69%. This sample represents one of the largest …

Unsupervised Oct Image Interpolation Using Deformable Registration And Generative Models, Shuwen Wei, Samuel W. Remedios, Bruno Jedynak, Peter Calabresi, Shiv Saidha, Aaron Carass, Multiple Additional Authors

Mathematics and Statistics Faculty Publications and Presentations

Optical coherence tomography (OCT) images are often acquired as highly anisotropic volumes, where the scanning step is dense along the fast axis but sparse along the slow axis. This affects image analysis, such as image registration for longitudinal alignment. To create more isotropic volumes, bicubic interpolation can be used along the slow axis, but it generally produces blurry features. Registration-based interpolation can reduce blurriness, but often fails to generate realistic OCT images. Deep generative models can sample realistic images, but lack the structural consistency constraints required for interpolation. In this paper, we propose an unsupervised image interpolation method that combines …

Metabarcoding-Biomass Relationships And Internal Standards For Quantitative Dna Metabarcoding, Frances Webber

Open Access Master's Theses

DNA metabarcoding has been widely adopted due to its power in investigating the composition of protistan communities, accurately identifying even small and cryptic taxa. However, the compositional nature of DNA metabarcoding results, and the distortion of natural abundances due to variation of the often-used 18S rRNA gene copy number over several orders of magnitude, renders these results semi-quantitative at best, limiting the application of DNA metabarcoding to ecological study. Here, we constructed mock communities from uni-algal cultures of taxonomically diverse phytoplankton and conducted metabarcoding using multiple primer sets and both DNA and cDNA as PCR templates. For each culture, chlorophyll …

A Compact Frequency Comb Generator For Large-Format Superconducting Microwave Kinetic Inductance Detectors, Sungyoun Seo

Open Access Master's Theses

Microwave Kinetic Inductance Detectors (MKIDs) are promising superconducting detectors that achieve superior sensitivity to silicon-based photo detectors by leveraging a small bandgap of superconductors. They are advantageous for sensitive imaging instruments, particularly space telescopes. However, a large-format array with several hundreds of thousands of detectors is required for large-scale observations in space, and it encounters multiple challenges. The biggest challenge is the absence of compact, energy-efficient, and radiation-tolerant readout solutions. Of multiple functions in the MKID readout, the new frequency comb generator is presented in this thesis. It features a low on-chip memory requirement while promising the relaxed frequency resolution …

Big Cells, Big Impact: Unravelling Seasonal Patterns Of Net Primary Production In Narragansett Bay, Dominique Jae Lockwood

Open Access Master's Theses

Net primary production is a measurement of available energy, or the amount of biomass that phytoplankton produce during photosynthesis that fuels marine food webs and drives carbon cycling. Despite its ecological importance, net primary production is relatively understudied in comparison to chlorophyll-a, which is often used as a proxy for biomass rather than productivity. In this study, we measured size-fractionated net primary production and chlorophyll-a concentrations in Narragansett Bay over a 14-month period from January 2022 to February 2023. Weekly surface water samples were collected and filtered to distinguish between small (> 10 μm) and large ( …

Investigating Ventilation In The Amundsen Sea, Antarctica Using An Eddy-Permitting Regional Ocean Model, Lauren Kowalski

Open Access Master's Theses

The Amundsen Sea is not a known site of bottom water formation, yet the presence of Winter Water reveals the role of deep winter mixing. In this study, we investigate how the production of Winter Water within the Amundsen Sea leads to ventilation by introducing a surface tracer into a regional configuration of MITgcm with ECCO-constrained forcing conditions for the years from 1998 to 2023. Modeled mixed layer depths routinely reached depths of 300 m or deeper in coastal polynyas and along sea ice divergence zones, driven by changes in salinity from sea ice formation and wind stress. The annual …

Navigating Online Perceptions Of Offshore Wind On Social Media: Facebook Discussions On Recent Whale Strandings, Giselle Hausmann

Open Access Master's Theses

The Biden-Harris administration implemented a goal to achieve 30 GW of offshore wind energy by 2030 (US Department of Interior, 2021). The rapid increase in offshore wind activity on the East Coast, combined with NOAA’s declared unusual mortality event in 2016/2017, has sparked a discussion about offshore wind being a potential cause of whale deaths. This paper aims to analyze the discourse on offshore wind and whales through a content analysis of Facebook comments. Facebook pages from Massachusetts (The New England Aquarium), Rhode Island (Rhode Island DEM), New York (The Atlantic Marine Conservation Society), New Jersey (Marine Mammal Stranding Center), …

Risk Factors For Autism Spectrum Disorder: A Statistical And Machine Learning Perspective, Supti Biswas

Open Access Master's Theses

his study explores factors associated with autism spectrum disorder (ASD) through analysis of a rich dataset comprising maternal and child characteristics. The data were carefully cleaned and preprocessed to address missing values and ensure analytical consistency. Statistical analyses and advanced visualization techniques were used to uncover patterns linking ASD status with variables such as maternal age, prenatal smoking, and education level. To further assess predictive capacity and feature importance, multiple supervised machine learning algorithms - logistic regression, decision trees, random forests, and support vector machines (SVM) - were applied. ASD appears to be influenced by a complex interplay of demographic …

The Bodhi App: A Post-Trauma Self-Regulation App For People With Intellectual And Developmental Disabilities, Liam Cannon

Open Access Master's Theses

People in the United States living with intellectual and developmental disabilities (I/DD) often experience trauma at a disproportionate rate. Due to societal and personal barriers, individuals with I/DD have problems with gaining access to therapy, thus often having to live with the negative effects of their untreated trauma. The effects of untreated trauma can cause severe impairment which affects a person’s quality of life and emotional, social, and physical development.

Post-trauma self-regulation is a way of doing activities to regulate one’s emotions to help cope with the negative effects of trauma. It has been shown as an effective method of …

From Lawns To Life: Landscaping For Biodiversity On Mason’S Island, Margit Burgess

Open Access Master's Theses

The collapse of biodiversity is an existential threat to life on Earth. Residential landscapes, dominated by open lawns maintained in turfgrass, do not support biodiversity. In the United States, turfgrass has replaced native landscapes in over 40 million acres, with 500 square miles added each year (Tallamy, 2019). Of the 78% of the U.S. land that is privately owned, approximately 135 million acres - nearly twice the size of all national parks combined - are residential (Milesi et al., 2005). With a shift in private landscape management, this land could present a largely untapped opportunity for biodiversity restoration and social …

Micro- And Nano-Plastics Preparation And Their Impact On Cobetia Marina, Lauren Lamothe

Open Access Master's Theses

Plastic pollution has become an increasing threat to marine and coastal environments. Macroplastics derived from consumer waste are broken down by chemical and physical degradation processes, resulting in micro- and nano-plastics (MPs and NPs). This thesis presents an investigation into the MP and NP pollution in the sea surface microlayer (SSML). The SSML contains surface active compounds and natural and anthropogenic matter. This study provides insight into the deeper impacts on the transport and fate of MPs and NPs and on marine bacteria. The first chapter works through the breakdown of plastic particles with the use of a top-down approach …

Plastics And Their Interactions With Bacterial Biofilms Of Synechococcus Sp. Pcc 7002 And Escherichia Coli Nissle 1917, Jackson Zmich

Open Access Master's Theses

Plastic waste is a leading global pollutant with increasing concerns, as recent studies have shown that these wastes are not only concentrated on a macro scale but on a micro and nano scale. These micro- and nano- sized plastic particles, denoted as MPs and NPs, have been measured in marine and freshwater sources, air, food products, and within biosolids expelled from organisms, including humans. Due to their small size, MNPs are entering organisms through inhalation, ingestion, or dermal absorption. [1] Humans are ingesting MNPs daily, with median rates of approximately 200 ng/capita/day for children and 600 ng/capita/day for adults. [2] …

Fiber Optic Distributed Acoustic Sensing For Surface Wave Inversion In Terrestrial And Marine Environments, Constantine Coclin

Open Access Master's Theses

The use of distributed acoustic sensing (DAS) has gained popularity for a variety of seismic sensing applications due to its capability to sense broadband frequency ranges on spatial scales unattainable with conventional point sensors. The ability to sense and characterize vibrational surface waves in the near-surface can provide valuable information about the subsurface structure of an environment. The objective of this study is to evaluate the use of DAS to sense surface wave propagation for the multi-channel analysis of surface waves (MASW) methodology, such that a sub-surface shear wave velocity profile can be obtained in both a terrestrial and near-shore …