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Articles 150331 - 150360 of 294391

Full-Text Articles in Physical Sciences and Mathematics

A Distributed Control Algorithm For Small Swarms In Cordon And Patrol, C Kristopher Alder Jun 2016

A Distributed Control Algorithm For Small Swarms In Cordon And Patrol, C Kristopher Alder

Student Works

Distributed teams of air and ground robots have the potential to be very useful in a variety of application domains, and much work is being done to design distributed algorithms that produce useful behaviors. This thesis presents a set of distributed algorithms that operate under minimal human input for patrol and cordon tasks. The algorithms allow the team to surround and travel between objects of interest. Empirical analyses indicate that the surrounding behaviors are robust to variations on the shape of the object of interest, communication loss, and robot failures.


Efficient Experimental Design Strategies In Toxicology And Bioassay, Timothy O'Brien Jun 2016

Efficient Experimental Design Strategies In Toxicology And Bioassay, Timothy O'Brien

Mathematics and Statistics: Faculty Publications and Other Works

Modelling in bioassay often uses linear or nonlinear logistic regression models, and relative potency is often the focus when two or more compounds are to be compared. Estimation in these settings is typically based on likelihood methods. Here, we focus on the 3-parameter model representation given in Finney (1978) in which the relative potency is a model parameter. Using key matrix results and the general equivalence theorem of Kiefer & Wolfowitz (1960), this paper establishes key design properties of the optimal design for relative potency using this model. We also highlight aspects of subset designs for the relative potency parameter …


Representation And Gaussian Bounds For The Density Of Brownian Motion With Random Drift, Azmi Makhlouf Jun 2016

Representation And Gaussian Bounds For The Density Of Brownian Motion With Random Drift, Azmi Makhlouf

Communications on Stochastic Analysis

No abstract provided.


Clark Formula For Local Time For One Class Of Gaussian Processes, A A Dorogovtsev, O L Izyumtseva, G V Riabov, Naoufel Salhi Jun 2016

Clark Formula For Local Time For One Class Of Gaussian Processes, A A Dorogovtsev, O L Izyumtseva, G V Riabov, Naoufel Salhi

Communications on Stochastic Analysis

No abstract provided.


Estimation Of Change Point Via Kalman-Bucy Filter For Linear Systems Driven By Fractional Brownian Motions, M N Mishra, B L S Prakasa Rao Jun 2016

Estimation Of Change Point Via Kalman-Bucy Filter For Linear Systems Driven By Fractional Brownian Motions, M N Mishra, B L S Prakasa Rao

Communications on Stochastic Analysis

No abstract provided.


Rapid Android Parser For Investigating Dex Files (Rapid), Xiaolu Zhang, Frank Breitinger, Ibrahim Baggili Jun 2016

Rapid Android Parser For Investigating Dex Files (Rapid), Xiaolu Zhang, Frank Breitinger, Ibrahim Baggili

Electrical & Computer Engineering and Computer Science Faculty Publications

Android malware is a well-known challenging problem and many researchers/vendors/practitioners have tried to address this issue through application analysis techniques. In order to analyze Android applications, tools decompress APK files and extract relevant data from the Dalvik EXecutable (DEX) files. To acquire the data, investigators either use decompiled intermediate code generated by existing tools, e.g., Baksmali or Dex2jar or write their own parsers/dissemblers. Thus, they either need additional time because of decompiling the application into an intermediate representation and then parsing text files, or they reinvent the wheel by implementing their own parsers. In this article, we present Rapid Android …


The Elder Scrolls V: Skyrim Stamina Combat Overhaul, Richard Rattner Jun 2016

The Elder Scrolls V: Skyrim Stamina Combat Overhaul, Richard Rattner

Liberal Arts and Engineering Studies

No abstract provided.


Visual Code: Breaking The Binary, Jacob Johannesen, Andrew Adriance Jun 2016

Visual Code: Breaking The Binary, Jacob Johannesen, Andrew Adriance

Liberal Arts and Engineering Studies

This project seeks to create an accessible programming language that is more visually based. Although some solutions exist, namely MIT’s Scratch, nothing has caught up to the mobile age. This proj- ect aims to reframe creating a game or app into the context of tell- ing a story, putting character creation first. By researching sto- ry-telling and how people learn, and by applying technical and user interface design knowledge, this project intends to deliver a soft- ware solution that opens introductory coding education to more people.


Metals Additive Manufacturing Powder Aging Characterization, Thomas Russell Lovejoy, Nicholas Karl Muetterties, David Takeo Otsu Jun 2016

Metals Additive Manufacturing Powder Aging Characterization, Thomas Russell Lovejoy, Nicholas Karl Muetterties, David Takeo Otsu

Mechanical Engineering

The metallic additive manufacturing process known as selective laser melting requires highly spherical, normally distributed powder with diameters in the range of 10 to 50 microns. Previous observations have shown a degradation in powder quality over time, resulting in unwanted characteristics in the final printed parts. 21-6-9 stainless steel powder was used to fabricate test parts, with leftover powder recycled back into the machine. Powder samples and test specimens were characterized to observe changes across build cycles. Few changes were observed in the physical and mechanical properties of the specimens, however, there were indications of chemical changes across cycles. Potential …


Novel Protein Disulfide Isomerase Inhibitor With Anticancer Activity In Multiple Myeloma, Sergei Vatolin, James G. Phillips, Babal K. Jha, Shravya Govindgari, Jennifer Hu, Dale Grabowski, Yvonne Parker, Daniel J. Lindner, Fei Zhong, Clark W. Distelhorst, Mitchell R. Smith, Claudiu Cotta, Yan Xu, Sujatha Chilakala, Rebecca R. Kuang, Samantha Tall, Frederic J. Reu Jun 2016

Novel Protein Disulfide Isomerase Inhibitor With Anticancer Activity In Multiple Myeloma, Sergei Vatolin, James G. Phillips, Babal K. Jha, Shravya Govindgari, Jennifer Hu, Dale Grabowski, Yvonne Parker, Daniel J. Lindner, Fei Zhong, Clark W. Distelhorst, Mitchell R. Smith, Claudiu Cotta, Yan Xu, Sujatha Chilakala, Rebecca R. Kuang, Samantha Tall, Frederic J. Reu

Chemistry Faculty Publications

Multiple myeloma cells secrete more disulfide bond–rich proteins than any other mammalian cell. Thus, inhibition of protein disulfide isomerases (PDI) required for protein folding in the endoplasmic reticulum (ER) should increase ER stress beyond repair in this incurable cancer. Here, we report the mechanistically unbiased discovery of a novel PDI-inhibiting compound with antimyeloma activity. We screened a 30,355 small-molecule library using a multilayered multiple myeloma cell–based cytotoxicity assay that modeled disease niche, normal liver, kidney, and bone marrow. CCF642, a bone marrow–sparing compound, exhibited a submicromolar IC50 in 10 of 10 multiple myeloma cell lines. An active biotinylated analog …


Criteria For Selecting Pegylation Sites On Proteins For Higher Thermodynamic Stability, Paul B. Lawrence Jun 2016

Criteria For Selecting Pegylation Sites On Proteins For Higher Thermodynamic Stability, Paul B. Lawrence

Theses and Dissertations

PEGylation of protein side-chains has been used for more than 30 years to enhance the pharmacokinetic properties of protein drugs, and has been enabled by the recent development of many chemoselective reactions for protein side-chain modification. However, there are no structure- or sequence-based guidelines for selecting sites that provide optimal PEG-based pharmacokinetic enhancement with minimal loss to biological activity. Chapter 1 is a brief introduction to protein PEGylation. In chapter 2 we use the WW domain of the human protein Pin 1 (WW) as a model system to probe the impact of PEG on protein conformational stability. Using a combination …


Optimal Density Bounds For Marginals Of Itô Processes, David Baños, Paul Krühner Jun 2016

Optimal Density Bounds For Marginals Of Itô Processes, David Baños, Paul Krühner

Communications on Stochastic Analysis

No abstract provided.


Continuity Of Random Fields On Riemannian Manifolds, Annika Lang, Jürgen Potthoff, Martin Schlather, Dimitri Schwab Jun 2016

Continuity Of Random Fields On Riemannian Manifolds, Annika Lang, Jürgen Potthoff, Martin Schlather, Dimitri Schwab

Communications on Stochastic Analysis

No abstract provided.


The Continuity Of The Solution Of The Natural Equation In The One-Dimensional Case, Fatima Benziadi, Abdeldjabbar Kandouci Jun 2016

The Continuity Of The Solution Of The Natural Equation In The One-Dimensional Case, Fatima Benziadi, Abdeldjabbar Kandouci

Communications on Stochastic Analysis

No abstract provided.


The Product Of Distributions And White Noise Distribution-Valued Stochastic Differential Equations, Hui-Hsiung Kuo, Kimiaki Saitô, Yusuke Shibata Jun 2016

The Product Of Distributions And White Noise Distribution-Valued Stochastic Differential Equations, Hui-Hsiung Kuo, Kimiaki Saitô, Yusuke Shibata

Communications on Stochastic Analysis

No abstract provided.


A Language-Based Model For Specifying And Staging Mixed-Initiative Dialogs, Saverio Perugini, Joshua W. Buck Jun 2016

A Language-Based Model For Specifying And Staging Mixed-Initiative Dialogs, Saverio Perugini, Joshua W. Buck

Computer Science Faculty Publications

Specifying and implementing flexible human-computer dialogs, such as those used in kiosks, is complex because of the numerous and varied directions in which each user might steer a dialog. The objective of this research is to improve dialog specification and implementation. To do so we developed a model for specifying and staging mixed-initiative dialogs. The model involves a dialog authoring notation, based on concepts from programming languages, for specifying a variety of unsolicited reporting, mixed-initiative dialogs in a concise representation that serves as a design for dialog implementation. Guided by this foundation, we built a dialog staging engine which operationalizes …


Math Department Newsletter, 2015-2016, Mathematics Department Jun 2016

Math Department Newsletter, 2015-2016, Mathematics Department

Mathematics Newsletter

No abstract provided.


Bunch Splitting Simulations For The Jleic Ion Collider Ring, R. Gamage, T. Satogata Jun 2016

Bunch Splitting Simulations For The Jleic Ion Collider Ring, R. Gamage, T. Satogata

Physics Faculty Publications

We describe the bunch splitting strategies for the proposed JLEIC ion collider ring at Jefferson Lab. This complex requires an unprecedented 9:6832 bunch splitting, performed in several stages. We outline the problem and current results, optimized with ESME including general parameterization of 1:2 bunch splitting for JLEIC parameters.


The Influence Of Juncus-Rhizosphere Dissolved Organic Matter On Coastal Plankton Communities, Brittany Zepernick, Robert Michael Mckay, George S. Bullerjahn, Jeffrey W. Krause, Behzad Mortazavi Jun 2016

The Influence Of Juncus-Rhizosphere Dissolved Organic Matter On Coastal Plankton Communities, Brittany Zepernick, Robert Michael Mckay, George S. Bullerjahn, Jeffrey W. Krause, Behzad Mortazavi

Honors Projects

Many aquatic plants produce copious amounts of dissolved organic matter (DOM) which enters surrounding waters and potentially stimulates planktonic activity. In the northern Gulf of Mexico, Juncus roemarianus (i.e. black needlerush) is a dominant marsh grass species residing in coastal zones and barrier islands. The below-ground biomass i.e. rhizosphere, can be consistently submerged, serving as a potential source of DOM to the surrounding waters. The lability and possible stimulatory effect of J. roemarianus DOM was examined for three plankton communities collected within the discharge region of Mobile Bay and adjacent waters of Gulf Shores, Alabama (less affected by Mobile Bay). …


Femtosecond Gas Phase Electron Diffraction With Mev Electrons, Jie Yang, Markus Guehr, Theodore Vecchione, Matthew S. Robinson, Renkai Li, Nick Hartmann, Xiaozhe Shen, Ryan Coffee, Jeff Corbett, Alan Fry, Kelly Gaffney, Tais Gorkhover, Carsten Hast, Keith Jobe, Igor Makasyuk, Alexander Reid, Joseph Robinson, Sharon Vetter, Fenglin Wang, Stephen Weathersby, Charles Yoneda, Xijie Wang, Martin Centurion Jun 2016

Femtosecond Gas Phase Electron Diffraction With Mev Electrons, Jie Yang, Markus Guehr, Theodore Vecchione, Matthew S. Robinson, Renkai Li, Nick Hartmann, Xiaozhe Shen, Ryan Coffee, Jeff Corbett, Alan Fry, Kelly Gaffney, Tais Gorkhover, Carsten Hast, Keith Jobe, Igor Makasyuk, Alexander Reid, Joseph Robinson, Sharon Vetter, Fenglin Wang, Stephen Weathersby, Charles Yoneda, Xijie Wang, Martin Centurion

Martin Centurion Publications

We present results on ultrafast gas electron diffraction (UGED) experiments with femtosecond resolution using the MeV electron gun at SLAC National Accelerator Laboratory. UGED is a promising method to investigate molecular dynamics in the gas phase because electron pulses can probe the structure with a high spatial resolution. Until recently, however, it was not possible for UGED to reach the relevant timescale for the motion of the nuclei during a molecular reaction. Using MeV electron pulses has allowed us to overcome the main challenges in reaching femtosecond resolution, namely delivering short electron pulses on a gas target, overcoming the effect …


Mathematical Reasoning And The Inductive Process: An Examination Of The Law Of Quadratic Reciprocity, Nitish Mittal Jun 2016

Mathematical Reasoning And The Inductive Process: An Examination Of The Law Of Quadratic Reciprocity, Nitish Mittal

Electronic Theses, Projects, and Dissertations

This project investigates the development of four different proofs of the law of quadratic reciprocity, in order to study the critical reasoning process that drives discovery in mathematics. We begin with an examination of the first proof of this law given by Gauss. We then describe Gauss’ fourth proof of this law based on Gauss sums, followed by a look at Eisenstein’s geometric simplification of Gauss’ third proof. Finally, we finish with an examination of one of the modern proofs of this theorem published in 1991 by Rousseau. Through this investigation we aim to analyze the different strategies used in …


Waldschmidt Constant For Squarefree Monomial Ideals, Christian Bocci, Susan Cooper, Elena Guardo, Brian Harbourne, Mike Janssen, Uwe Nagel, Alexandra Seceleanu, Adam Van Tuyl, Thanh Vu Jun 2016

Waldschmidt Constant For Squarefree Monomial Ideals, Christian Bocci, Susan Cooper, Elena Guardo, Brian Harbourne, Mike Janssen, Uwe Nagel, Alexandra Seceleanu, Adam Van Tuyl, Thanh Vu

Faculty Work Comprehensive List

Given a squarefree monomial ideal I ⊆ R = k[x1, . . . , xn], we show that α(I), the Waldschmidt constant of I, can be expressed as the optimal solution to a linear program constructed from the primary decomposition of I. By applying results from fractional graph theory, we can then express α(I) in terms of the fractional chromatic number of a hypergraph also constructed from the primary decomposition of I. Moreover, expressing α(I) as the solution to a linear program enables us to prove a Chudnovsky-like lower bound on α(I), thus verifying …


The Kauffman Bracket And Genus Of Alternating Links, Bryan M. Nguyen Jun 2016

The Kauffman Bracket And Genus Of Alternating Links, Bryan M. Nguyen

Electronic Theses, Projects, and Dissertations

Giving a knot, there are three rules to help us finding the Kauffman bracket polynomial. Choosing knot’s orientation, then applying the Seifert algorithm to find the Euler characteristic and genus of its surface. Finally finding the relationship of the Kauffman bracket polynomial and the genus of the alternating links is the main goal of this paper.


Supramolecular Assembly Of Metal-Organic Tubes Constructed From The Ditopic Heteroscorpionate Ligand (4-Nh2C6H4)Chpz2 (Pz = Pyrazol-1-Yl) And Silver(I), James R. Gardinier, Jeewantha S. Hewage, Justin Hoffman, Sergey V. Lindeman, Natalia B. Shustova Jun 2016

Supramolecular Assembly Of Metal-Organic Tubes Constructed From The Ditopic Heteroscorpionate Ligand (4-Nh2C6H4)Chpz2 (Pz = Pyrazol-1-Yl) And Silver(I), James R. Gardinier, Jeewantha S. Hewage, Justin Hoffman, Sergey V. Lindeman, Natalia B. Shustova

Chemistry Faculty Research and Publications

The possibility of constructing tubular metal-organic structures with aid of weak hydrogen-bonding interactions between suitably designed metallacycles was explored. For this purpose, the new heteroditopic ligand (4-NH2C6H4)CHpz2 (L1) was prepared in good (75 %) yield by a one-pot procedure starting from commercial 4-acetamidobenzaldehyde. The equimolar reactions between L1 and various silver(I) salts gave the intended 1:1 complexes in which the metallacycles were assembled into tubes. However, the exact nature of the assemblies (including their solvate compositions) varied depending on anion, solvent, and concentration of the original crystallization solution. For the trifluoromethanesulfonate anion, a …


Mononuclear Iron-(Hydro/Semi)Quinonate Complexes Featuring Neutral And Charged Scorpionates: Synthetic Models Of Intermediates In The Hydroquinone Dioxygenase Mechanism, Amanda E. Baum, Sergey V. Lindeman, Adam T. Fiedler Jun 2016

Mononuclear Iron-(Hydro/Semi)Quinonate Complexes Featuring Neutral And Charged Scorpionates: Synthetic Models Of Intermediates In The Hydroquinone Dioxygenase Mechanism, Amanda E. Baum, Sergey V. Lindeman, Adam T. Fiedler

Chemistry Faculty Research and Publications

Neutral and anionic scorpionate ligands have been employed to generate active-site models of hydroquinone dioxygenases (HQDOs). While the nonheme Fe center in nearly all HQDOs is coordinated to one Asp (or Glu) and two His residues, 1,2-gentisate dioxygenase (GDO) is unique in featuring a three His triad instead. A synthetic GDO model was therefore prepared with the neutral tris(4,5-diphenyl-1-methylimidazol-2-yl)phosphine (Ph2TIP) ligand. The gentisate substrate was mimicked with the bidentate ligand 2-(1-methylbenzimidazol-2-yl)hydroquinonate (BIHQ). X-ray diffraction analysis of the resulting complex, [Fe(Ph2TIP)(BIHQ)]OTf (1a), revealed a distorted square-pyramidal geometry. Structural and electrochemical data collected for 1a were compared to …


Empirical Research And Practice-Oriented Physics For The Humanities And Sciences, István Berszán Jun 2016

Empirical Research And Practice-Oriented Physics For The Humanities And Sciences, István Berszán

CLCWeb: Comparative Literature and Culture

In his article "Empirical Research and Practice-oriented Physics for the Humanities and Sciences" István Berszán proposes an empirical approach for the humanities and sciences he designates as "practice-oriented physics." He bases his argumentation on Albert-László Barabási's network theory applied and question tenets of complexity, networks, and spaces. Further, Berszán elaborates on the affinity between the spaces of practical orientation and the spaciousness of parallel worlds as explicated in Brian Green's string theory. Berszán posits that because the universe as "symphony" of string oscillations leads to parallel rhythms of happenings and their different spaces of motion and argues that this kind …


Application Of Computer Modeling And Simulation Techniques For Optimization Of Factory Floor Operations In Small To Medium- Sized Businesses, Brian P. Romano Jun 2016

Application Of Computer Modeling And Simulation Techniques For Optimization Of Factory Floor Operations In Small To Medium- Sized Businesses, Brian P. Romano

Theses and Dissertations

The rationale and motive for this thesis was to prove that no matter the size of a company and its particular value stream, the application of applied computer science principles with a reliance on computer modeling and simulation onto the factory floor process improves efficiencies and throughput through the reduction of downtime and/or process waiting. This thesis research specifically emphasized small businesses of between $2 and $20 million and was purposely limited to factory floor production processes and utilized standardized applied computer science techniques including simulation and modeling, microprocessor based factory floor intelligence devices. The results of this applied technology …


Testing Multiple Hypotheses With Skewed Alternatives, Naveen K. Bansal, Gholamhossein G. Hamedani, Mehdi Maadooliat Jun 2016

Testing Multiple Hypotheses With Skewed Alternatives, Naveen K. Bansal, Gholamhossein G. Hamedani, Mehdi Maadooliat

Mathematics, Statistics and Computer Science Faculty Research and Publications

In many practical cases of multiple hypothesis problems, it can be expected that the alternatives are not symmetrically distributed. If it is known a priori that the distributions of the alternatives are skewed, we show that this information yields high power procedures as compared to the procedures based on symmetric alternatives when testing multiple hypotheses. We propose a Bayesian decision theoretic rule for multiple directional hypothesis testing, when the alternatives are distributed as skewed, under a constraint on a mixed directional false discovery rate. We compare the proposed rule with a frequentist's rule of Benjamini and Yekutieli (2005) using simulations. …


Inter-Species Entanglement Of Bose-Bose Mixtures Trapped In Optical Lattices, Wei Wang, Vittorio Penna, Barbara Capogrosso-Sansone Jun 2016

Inter-Species Entanglement Of Bose-Bose Mixtures Trapped In Optical Lattices, Wei Wang, Vittorio Penna, Barbara Capogrosso-Sansone

Physics

In the present work we discuss inter-species entanglement in Bose-Bose mixtures trapped in optical lattices. This work is motivated by the observation that, in the presence of a second component, the MI lobe shifts differently on the hole- and particle-side with respect to the Mott lobe of the single species system (Guglielmino et al 2010 Phys. Rev. A 82 021601; Capogrosso-Sansone et al 2011 Laser Phys. 21 1443). We use perturbation theory, formulated in a Hilbert space decomposed by means of lattice symmetries, in order to show that the nonuniform shift of the Mott lobe is a manifestation of inter-species …


Daytime Variation Of Urban Heat Islands: The Case Study Of Doha, Qatar, Yasuyo Makido, Vivek Shandas, Salim Ferwati, David J. Sailor Jun 2016

Daytime Variation Of Urban Heat Islands: The Case Study Of Doha, Qatar, Yasuyo Makido, Vivek Shandas, Salim Ferwati, David J. Sailor

Urban Studies and Planning Faculty Publications and Presentations

Recent evidence suggests that urban forms and materials can help to mediate temporal variation of microclimates and that landscape modifications can potentially reduce temperatures and increase accessibility to outdoor environments. To understand the relationship between urban form and temperature moderation, we examined the spatial and temporal variation of air temperature throughout one desert city—Doha, Qatar—by conducting vehicle traverses using highly resolved temperature and GPS data logs to determine spatial differences in summertime air temperatures. To help explain near-surface air temperatures using land cover variables, we employed three statistical approaches: Ordinary Least Squares (OLS), Regression Tree Analysis (RTA), and Random Forest …