Physical Sciences and Mathematics Commons^™

99mtc-Hexamethylpropyleneamine Oxime Imaging For Early Detection Of Acute Lung Injury In Rats Exposed To Hyperoxia Or Lipopolysaccharide Treatment, Said H. Audi, Anne V. Clough, Steven T. Haworth, Meetha Medhora, Mahsa Ranji, John C. Densmore, Elizabeth R. Jacobs

Biomedical Engineering Faculty Research and Publications

^99mTc-Hexamethylpropyleneamine oxime (HMPAO) is a clinical single-photon emission computed tomography biomarker of tissue oxidoreductive state. Our objective was to investigate whether HMPAO lung uptake can serve as a preclinical marker of lung injury in two well-established rat models of human acute lung injury (ALI).

Rats were exposed to >95% O₂ (hyperoxia) or treated with intratracheal lipopolysaccharide (LPS), with first endpoints obtained 24 h later. HMPAO was administered intravenously before and after treatment with the glutathione-depleting agent diethyl maleate (DEM), scintigraphy images were acquired, and HMPAO lung uptake was quantified from the images. We also measured breathing rates, heart …

The Firece Green Fire: Vol. 7 Issue 4, Wofford College Environmental Studies Program

The Fierce Green Fire

No abstract provided.

Inverse Laplace Transform And Post Inversion Formula, Qinmao Zhang

Mathematical Sciences Technical Reports (MSTR)

This paper is dedicated to a general numerical approach to inverse Laplace transforms based on the Post Inversion Formula, which is a theoretical equivalent to the inverse Laplace transform. Though most approaches are too computationally intensive to be of practical use, we introduce an efficient algorithm to compute it based on the Parker-Sochacki method (PSM). This paper also contains some example MATLAB code and algorithm analysis.

Presence, Absence, And Roosting Ecology Of The Southeastern Myotis And Rafinesque's Big-Eared Bat In The Cache River National Wildlife Refuge, Samuel Andrew Schratz

Student Theses and Dissertations

Four bat species, 2 of special concern, the southeastern myotis (Myotis austroriparius), and Rafinesque’s big-eared bat (Corynorhinus rafinesquii) and 2 threatened and endangered species may occur in one of Arkansas’ largest bottomland hardwood forests, the Cache River National Wildlife Refuge. However, inventory of bat species throughout the refuge is lacking and management plans may not be adequate in promoting the conservation of bats. My goal was to inventory the bats of the Cache River National Wildlife Refuge and determine roosting habits of the southeastern myotis and Rafinesque’s big-eared bat. During summers 2014 and 2015, surveys were conducted throughout the refuge. …

Infrared Polarimetry Of Mrk 231: Scattering Off Hot Dust Grains In The Central Core, E. Lopez-Rodriguez, C. Packham, T. J. Jones, R. Siebenmorgen, P. F. Roche, N. A. Levenson, A. Alonso-Herrero, E. Perlman, K. Ichikawa, C. Ramos Almeida, O. Gonzalez-Martin, R. Nikutta, M. Martinez-Paredez, D. Shenoy, M. S. Gordon, C. M. Telesco

Aerospace, Physics, and Space Science Faculty Publications

We present high-angular (0.17–0.35 arcsec) resolution imaging polarimetric observations of Mrk 231 in the 3.1 μm filter using MMT-Pol on the 6.5-m MMT, and in the 8.7, 10.3, and 11.6 μm filters using CanariCam on the 10.4-m Gran Telescopio CANARIAS. In combination with already published observations, we compile the 1–12 μm total and polarized nuclear spectral energy distribution (SED). The total flux SED in the central 400 pc is explained as the combination of (1) a hot (731 4 K) dusty structure, directly irradiated by the central engine, which is at 1.6 0.1 pc away and attributed to be in …

The Impact Of Low Self-Control On Online Harassment: Interaction With Opportunity., Hyunin Baek, Michael M. Losavio, George E. Higgins

Journal of Digital Forensics, Security and Law

Developing Internet technology has increased the rates of youth online harassment. This study examines online harassment from adolescents with low self-control and the moderating effect of opportunity. The data used in this study were collected by the Korea Institute of Criminology in 2009. The total sample size was 1,091. The results indicated that low self-control, opportunity, and gender have a significant influence on online harassment. However, these results differed according to gender; for males, low self-control significantly impacted online harassment; for females, however, only low self-control significantly impacted online harassment. Furthermore, the interaction between low self-control and opportunity did not …

A Legal Examination Of Revenge Pornography And Cyber-Harassment, Thomas Lonardo, Tricia Martland, Doug White

Journal of Digital Forensics, Security and Law

This paper examines the current state of the statutes in the United States as they relate to cyber-harassment in the context of "revenge porn". Revenge porn refers to websites which cater to those wishing to exploit, harass, or otherwise antagonize their ex partners using pornographic images and videos which were obtained during their relationships. The paper provide examples and illustrations as well as a summary of current statute in the United States. The paper additionally explores some of the various legal remedies available to victims of revenge pornography.

A Geometric Model Of Twisted Differential K-Theory, Byung Do Park

Dissertations, Theses, and Capstone Projects

We construct a model of even twisted differential K-theory when the underlying topological twist represents a torsion class. We use smooth U(1)-gerbes with connection as differential twists and twisted vector bundles with connection as cycles. The model we construct satisfies the axioms of Kahle and Valentino, including functoriality, naturality of twists, and the hexagon diagram. We also construct an odd twisted Chern character of a twisted vector bundle with an automorphism. In addition to our geometric model of twisted differential K-theory, we introduce a smooth variant of the Hopkins-Singer model of differential K-theory. We prove that our model is naturally …

Photonic Crystals With Alternate Arrays Of Rods And Holes In A Low Dielectric-Index Material, Dimitar L. Dimitrov

Dissertations, Theses, and Capstone Projects

This thesis theoretically deals with the propagation of electromagnetic waves (light beams) in periodically modulated dielectric material structures based on Maxwell’s equations. We are interested in novel light propagation characteristics in these man-made dielectric material structures for practical applications, especially on optical communications and computations. Since the wavelength range of light is on the same order of magnitude as the modulation periods of dielectric materials, an analogy of the light propagation in dielectric-constant modulated structures with the electron transport in solid-state crystals is used throughout my thesis by using a term “photonic crystals (PhCs)” referring to these dielectric structures. I …

Electrochemical Nanoprobes For Electron Transfer Kinetics And Electrocatalysis Study, Yun Yu

Dissertations, Theses, and Capstone Projects

The studies of electrochemical processes on the nanoscale have led to a significant progress in understanding of electrochemical mechanisms and characterization of nanomaterials in the fields of energy, catalysis, and biological research. Electrochemical experiments at nanoscale require the fabrication and characterization of nanometer-sized electrochemical probes. The main advantages of the nanoprobes include very fast mass-transfer rate, high signal-to-noise ratio and extremely fine spatial resolution of electrochemical imaging. In the course of my Ph.D. research, different types of electrochemical probes were developed for measuring electron-transfer kinetics, probing single catalytic nanoparticles and sampling ultra-small volume of liquids.

We developed methodologies to fabricate …

Development Of New Radiolabeling Methods And Insights On Ionizing Radiation Interactions With Nanoparticles, Travis Shaffer

Dissertations, Theses, and Capstone Projects

Nanoparticles are often combined with radionuclides for various applications, ranging from waste remediation to imaging and therapy in the medical field. The overarching aim of this body of work is two-fold. The first aim is development of new radiolabeling methods for various nanoparticles that allow stable attachment of a variety of imaging and therapeutic radionuclides. The second portion more fully describes mechanisms of interaction between ionizing radiation and nanoparticles.

The following advancements will be presented in this dissertation: i) a new radiolabeling method for silica and silica-based nanoparticles that does not require the use of specific chelators, with both radiochemical …

Transmission Of Focused Picosecond Light Pulse Through Multimode Fibers, Yin Cen

Dissertations, Theses, and Capstone Projects

This thesis focuses on a technique of delivering spatially focused and temporally compressed picosecond laser pulses through multimode fibers. This study was inspired by recent success in focusing light through optically diffusive media of which multimode fibers were a special case in terms of causing scrambled phase distribution in the transmitted light. The approach involved controlling the phase distribution of incoming beam using a deformable mirror prior to its entry into the multimode fiber in order to achieve constructive interference at selected spots in the output. With phase control, the intensity of the focused light at the output can be …

Sustainable Molecular Gelators: Beta-D-Glucoside Derived Structuring Agents And Their Material Application, Julian R. Silverman

Dissertations, Theses, and Capstone Projects

Though molecular gelators may by synthesized and formulated into gels following a variety of methods, it should serve that the most valued methods may utilize renewable and waste resources and follow sustainable procedures. Molecular gelators are systems capable of structuring liquids into solid-like materials and they represent a class of surfactant and amphiphilic materials which posses the capability to be not only useful in their ability to form gels, but multifunctional in the ability to respond smartly to a variety of stimuli. Thus there is an interest in the development of sustainable molecular gelators capable of being applied to applications, …

Explicit Reciprocity Laws For Higher Local Fields, Jorge Florez

Dissertations, Theses, and Capstone Projects

In this thesis we generalize to higher dimensional local fields the explicit reciprocity laws of Kolyvagin for the Kummer pairing associated to a formal group. The formulas obtained describe the values of the pairing in terms of multidimensional p-adic differentiation, the logarithm of the formal group, the generalized trace and the norm on Milnor K-groups.

I. Synthesis Of Diverse Structures From Quinone Monoketal And Quinone Imine Ketal With Efficiency And Control Ii. Synthetic Study Of Phalarine, Zhiwei Yin

Dissertations, Theses, and Capstone Projects

Quinonoids are quinone derivatives that have carbonyl or carbonyl equivalent and even number of double bonds embedded in six member rings. As a result of the intrinsic α,β-unsaturated ketone or imine structures, quinonoids, such as quinone monoketals, quinols, quinol ethers and quinone imine ketals, can accommodate a wide range of reactions including 1,2-additon, 1,4-addtion, SN2’ reaction (allylic substitution) to the α-carbon of the carbonyl or imine and cycloaddition reactions (e.g. Diels-Alder reaction). Quinonoids are effective building blocks for synthesizing heterocycles, which are ubiquitous in pharmaceutically useful agents. Developing new quinonoid based methodologies is essential to expanding the boundary of synthetic …

Specific Binding Affinity Of The Non-Catalytic Domain Of Eukaryotic Like Type Ib Topoisomerase Of Vaccinia Virus, Benjamin R. Reed

Dissertations, Theses, and Capstone Projects

Topoisomerases are ubiquitous proteins that alter supercoiling in double stranded DNA (dsDNA) during transcription and replication and. vaccinia and the closely related poxvirus variola virus, at 314 amino acids in length, encode the smallest of the type I topoisomerases(TopIB). TopIB is a two domain protein that recognizes the sequence 5’-T/CCCTT, cleaves at the 3’-end and relaxes supercoiling through rotation. The C-terminal domain (CTD) alone contains the catalytic activity and specificity. Deletion of the N-terminal domain results in a greatly reduced rate of relaxation and rapid dissociation. Biochemical data suggests that the N-terminal domain (NTD) is important for pre-cleavage binding and …

Give-Me: Gamification In Virtual Environments For Multimodal Evaluation - A Framework, Wai L. Khoo

Dissertations, Theses, and Capstone Projects

In the last few decades, a variety of assistive technologies (AT) have been developed to improve the quality of life of visually impaired people. These include providing an independent means of travel and thus better access to education and places of work. There is, however, no metric for comparing and benchmarking these technologies, especially multimodal systems. In this dissertation, we propose GIVE-ME: Gamification In Virtual Environments for Multimodal Evaluation, a framework which allows for developers and consumers to assess their technologies in a functional and objective manner. This framework is based on three foundations: multimodality, gamification, and virtual reality. It …

Nmr Studies Of Electrochemical Energy Storage Materials, Jing Peng

Dissertations, Theses, and Capstone Projects

Electrochemical energy storage materials constitute essential elements in the development of sustainable energy technologies. They are crucial for improving the efficiency of energy storage devices to facilitate the use of renewable resources. The increasing human demands for energy and limitation of fossil fuel stimulates the continued development of energy storage materials. Better understanding of their working mechanisms and electrochemical properties from a view of chemistry is quite necessary for improving the energy storage technology. In this work, Nuclear Magnetic Resonance (NMR) has been used as a powerful tool to characterize the solvation behavior and diffusion ability of some commonly used …

Photodynamic Killing Of Human Cancer Cells With Smart Photosensitizer Materials And An Endoscopic Implement For Singlet Oxygen Delivery, Mihaela N. Minnis

Dissertations, Theses, and Capstone Projects

The thesis describes progress on probe tips for a microoptic device for the precise delivery of the components necessary for photodynamic therapy (PDT) in a highly localized and controllable fashion. The thesis also summarizes results of a photosensitized oxidation study. The work focused on i) developing a photoactive fluoropolymer surface that will release sensitizer drug molecule for use in PDT, ii) designing new probe tips surfaces for use as sensitizer support for a microoptic PDT device, iii) exploring strategies for covalent attachment of sensitizers and model compounds to Teflon/PVA surfaces with the aim of being coupled with our microoptic device, …

Guidance Index For Shallow Landslide Hazard Analysis, Cheila Cullen

Dissertations, Theses, and Capstone Projects

Rainfall-induced landslides are one of the most frequent hazards on slanted terrains. They lead to considerable economic losses and fatalities worldwide. Intense storms with high-intensity and long-duration rainfall have high potential to trigger rapidly moving soil masses due to changes in pore water pressure and seepage forces. Nevertheless, regardless of the intensity-duration of the rainfall, shallow landslides are influenced by antecedent soil moisture conditions. To the present day, no system exists that dynamically interrelates these two factors.

This work establishes a relationship between antecedent soil moisture and rainfall expressed in the form of a Shallow Landslide Index (SLI) at 1km …

Explicit Formulae And Trace Formulae, Tian An Wong

Dissertations, Theses, and Capstone Projects

In this thesis, motivated by an observation of D. Hejhal, we show that the explicit formulae of A. Weil for sums over zeroes of Hecke L-functions, via the Maass-Selberg relation, occur in the continuous spectral terms in the Selberg trace formula over various number fields. In Part I, we discuss the relevant parts of the trace formulae classically and adelically, developing the necessary representation theoretic background. In Part II, we show how show the explicit formulae intervene, using the classical formulation of Weil; then we recast this in terms of Weil distributions and the adelic formulation of Weil. As an …

Tuning Topological Surface States By Charge Transfer, Zhiyi Chen

Dissertations, Theses, and Capstone Projects

Three-dimensional (3D) topological insulators (TIs), Bi₂Se₃, Bi₂Te₃, Sb₂Te₃, are a class of materials that has non-trivial bulk band structure and metallic surface states. Access to charge transport through Dirac surface states in TIs can be challenging due to their intermixing with bulk states or non-topological two-dimensional electron gas quantum well states caused by bending of electronic bands near the surface. The band bending arises via charge transfer from surface adatoms or interfaces and, therefore, the choice of layers abutting topological surfaces is critical. Surfaces of these 3D TIs …

On Sums Of Binary Hermitian Forms, Cihan Karabulut

Dissertations, Theses, and Capstone Projects

In one of his papers, Zagier defined a family of functions as sums of powers of quadratic polynomials. He showed that these functions have many surprising properties and are related to modular forms of integral weight and half integral weight, certain values of Dedekind zeta functions, Diophantine approximation, continued fractions, and Dedekind sums. He used the theory of periods of modular forms to explain the behavior of these functions. We study a similar family of functions, defining them using binary Hermitian forms. We show that this family of functions also have similar properties.

Probing The Structure And Photophysics Of Porphyrinoid Systems For Functional Materials, Christopher D. Farley

Dissertations, Theses, and Capstone Projects

Porphyrins (Pors) and their many cousins, including phthalocyanines (Pcs), corroles (Cors), subphthalocyanines (SubPcs), porphyrazines (Pzs), and naphthalocyanines (NPcs), play amazingly diverse roles in biological and non-biological systems because of their unique and tunable physical and chemical properties. These compounds, collectively known as porphyrinoids, can be employed in any number of functional devices that have the potential to address the challenges of modern society. Their incorporation into such devices, however, depends on many structural factors that must be well understood and carefully controlled in order to achieve the desired behavior. Self-assembly and self-organization are key processes for developing these new technologies, …

Comprehensive Mass Balance Isotope Schematics For Determining The Provenance Of The Moon Forming Impactor., John C. Wolbeck

Dissertations, Theses, and Capstone Projects

The goal of this research was to identify areas where deviations from the canonic Moon forming impact scenario (an impactor approximately 12% of the mass of the Earth merging with 100% accretion efficiency with a proto-Earth each of which has a differentiated homologous anatomy of 30% iron and 70% silicates) may greatly reduce the efficacy of the impact mass balance analytics used to determine the provenance of the impactor based on isotope data from terrestrial and lunar samples and physical data from high resolution SPH computer simulations.

Modeling the giant Moon forming impact is complicated by a lack of knowledge …

Metabolic Profiling Of Genetically Modified Potato Periderm Tissues, Liqing Jin

Dissertations, Theses, and Capstone Projects

Potato tubers are protected from dehydration and pathogens by a covering peel (periderm) impregnated with suberin, a complex cross-linked biopolymer that contains both polyaliphatic and lignin-like aromatic domains. Current models describing the macromolecular structure of suberin assume that ferulic acid cross-links both domains as it may form carboxyl ester bonds with aliphatic monomers and non-ester radical-coupled bonds with phenolics. Ferulic acid also links by ester bonds to glycans and acts in cross-linking polysaccharides and lignin. Fatty alcohol/ω-hydroxyacid hydroxycinnamoyl transferase (FHT) is a BADH acyltransferase responsible for the synthesis of akyl-ferulates that is necessary for suberin biosynthesis. Periderm from FHT-RNAi …

Fundamental Parameters Of The Lowest Mass Stars To The Highest Mass Planets, Joseph C. Filippazzo

Dissertations, Theses, and Capstone Projects

The physical and atmospheric properties of ultracool dwarfs are deeply entangled due to the degenerate effects of mass, age, metallicity, clouds and dust, activity, rotation, and possibly formation mechanism on their observed properties. Accurate fundamental parameters for a wide range of substellar objects are crucial to testing stellar and planetary formation theories. To determine these quantities, we construct flux-calibrated spectral energy distributions (SEDs) for 234 M, L, T, and Y dwarfs and calculate bolometric luminosity (L_bol), effective temperature (T_eff), mass, surface gravity, radius, spectral indexes, synthetic photometry, and bolometric corrections (BCs) for each object. We use …

Estimation Of P(X > Y) When X And Y Are Dependent Random Variables Using Different Bivariate Sampling Schemes, Hani M. Samawi, Amal Helu, Haresh Rochani, Jingjing Yin, Daniel Linder

Biostatistics: Faculty Publications

The stress-strength models have been intensively investigated in the literature in regards of estimating the reliability θ = P (X > Y) using parametric and nonparametric approaches under different sampling schemes when X and Y are independent random variables. In this paper, we consider the problem of estimating θ when (X, Y) are dependent random variables with a bivariate underlying distribution. The empirical and kernel estimates of θ = P (X > Y), based on bivariate ranked set sampling (BVRSS) are considered, when (X, Y) are paired dependent continuous random variables. The estimators obtained are compared to their counterpart, bivariate simple random …

Table Of Contents

Journal of Digital Forensics, Security and Law

No abstract provided.

Special Issue On Cyberharassment Investigation: Advances And Trends, Joanne Bryce, Virginia N. L. Franqueira, Andrew Marrington

Journal of Digital Forensics, Security and Law

Empirical and anecdotal evidence indicates that cyberharassment is more prevalent as the use of social media becomes increasingly widespread, making geography and physical proximity irrelevant. Cyberharassment can take different forms (e.g., cyberbullying, cyberstalking, cybertrolling), and be motivated by the objectives of inflicting distress, exercising control, impersonation, and defamation. Little is currently known about the modus operandi of offenders and their psychological characteristics. Investigation of these behaviours is particularly challenging because it involves digital evidence distributed across the devices of both alleged offenders and victims, as well as online service providers, sometimes over an extended period of time. This special issue …