The Usefulness Of The Ultrasound Diagnosis Of Suspicious Ovarian Masses Based On The O-Rads Classification System, 2021 Radio-diagnosis, Al-Azhar university Assiut, Faculty of Medicine, Assiut , Egypt
The Usefulness Of The Ultrasound Diagnosis Of Suspicious Ovarian Masses Based On The O-Rads Classification System, Hoda Ahmed
Al-Azhar International Medical Journal
Objectives: Ovarian malignancy represent the leading cause of mortality from gynecologic cancers and its diagnosis is a special challenge. Ultrasonography is the primary imaging modality and the Ovarian-Adnexal Reporting and Data System (O-RADS) US was made to provide consistent interpretations that can help in management recommendation. The present study aimed to evaluate the usefulness of using the O-RADS classification system US in the diagnosis of suspicious ovarian masse lesions. Methods: Fifty patients " 15 pre and 35 post-menopausal" with suspicious adnexal mass lesions, their ages ranged from 19-67 years (M=41.8±3.64 years). Trans-abdominal & trans-vaginal US with Color/Power Doppler examination was …
Comparative Study Between Bipolar Electro-Cautery And Knot-Tying Technique In Total Thyroidectomy, 2021 general surgery-faculty of medicine-Al Azhar university-cairo-egypt
Comparative Study Between Bipolar Electro-Cautery And Knot-Tying Technique In Total Thyroidectomy, Ahmed Hegab
Al-Azhar International Medical Journal
Abstract Introduction: Thyroidectomy could be considered as the commonest neck surgery in surgical practice. Proper thyroidectomy requires careful and meticulous devascularization of the gland with preservation of surrounding important structures. Haemostasis during thyroidectomy achieved by suture ligation, electro-cautery or vessel sealing devices. The traditional knot-tying method requires carful dissection which is time consuming and may lead to injury of laryngeal nerves or impairment of blood supply to parathyroid glands. Bipolar electro-cautery has precise delivery of electric current between its tips with no or limited thermal dispersion to surrounding structures. Advanced vessel sealing devices not always available and requires special disposable …
The Association Between Helicobacter Pylori Infection And Hyperemesis Gravidarum, 2021 Obstetrics and gynecology, faculty of medicine for girls, Al-Azhar University , Cairo, Egypt
The Association Between Helicobacter Pylori Infection And Hyperemesis Gravidarum, Eman Mohamed, Samira Elmallah, Doaa Mohammed
Al-Azhar International Medical Journal
Background; Hyperemesis gravidarum (HG) is the severe kind of nausea and vomiting of gestation. The HG incidence is about 0.5-2.0%. For the diagnosis of HG, there must be the existence of 3 or more vomiting episodes throughout the day, weight losing of more than 5%, and ketonuria. Studies have recently suggested that there is a correlation between emesis of gravidarum and HG with Helicobacter pylori (H. pylori) infection. Serologically positive H. pylori infections were demonstrated in hyperemesis patients. Aim and objectives; the current work aimed to detect the correlation between H. pylori infections and HG throughout gestation. Subjects and methods; …
Perioperative Antibiotic Use In Neonatal General Surgery: A Survey Of Apsa Membership, 2021 Oakland University William Beaumont School of Medicine Student
Perioperative Antibiotic Use In Neonatal General Surgery: A Survey Of Apsa Membership, Ashley Williams, Samuel K. Osei, Pavan Brahmamdam, Begum Akay, Diane Studzinski
Conference Presentation Abstracts
Background: Surgical site infections (SSIs) are a significant source of perioperative morbidity. There is limited data regarding antibiotic prophylaxis in pediatrics, and there are no standardized guidelines in neonates. Thus, peri-operative antibiotic use is based on surgeon experience and preference. To explore this knowledge gap, we sought to describe the practice patterns of pediatric surgeons with regard to antibiotic prophylaxis for SSIs in neonatal surgery
Methods: A survey was distributed to the American Pediatric Surgical Association (APSA). Members were asked to respond to 6 hypothetical case scenarios: Tracheoesophageal fistula/Esophageal atresia, Hirschsprung’s disease, Gastroschisis, Congenital diaphragmatic hernia repair, Neonatal intestinal obstruction …
Bassini Inguinal Hernia Repair: Obsolete Or Still A Viable Surgical Option? A Single Center Cohort Study, 2021 Hunter Holmes McGuire VA Medical Center
Bassini Inguinal Hernia Repair: Obsolete Or Still A Viable Surgical Option? A Single Center Cohort Study, Wayne Tse, William Johns, James Maher, Jeannie Rivers, Thomas Miller
Department of Orthopaedic Surgery Faculty Papers
Background: Most inguinal hernias are presently repaired using some type of mesh technique. This mesh can be placed through an inguinal incision or positioned through a laparoscopic approach. Either way, results have been impressive including a low recurrence rate, minimal pain and a rapid return to work and normal activity compared to tissue based approaches. Notwithstanding these results, there is still a subset of patients who, for various reasons, are strongly opposed to having a mesh repair. This study summarizes our 13 year experience with such patients and why the Bassini hernia repair is a viable surgical option in these …
Serum Vitamin D Level And Bone Mineral Density Among Adolescent Idiopathic Scoliotic Patients, 2021 Professor of rheumatology and rehabilitation, Al-Azhar Faculty of medicine
Serum Vitamin D Level And Bone Mineral Density Among Adolescent Idiopathic Scoliotic Patients, Hesham Hammoud, Hany Aly, Mohamed Yehia, Mohamed Belih
Al-Azhar International Medical Journal
Background: Low bone mineral density (BMD) and low vitamin D were found to be in adolescent idiopathic scoliosis (AIS) patients. The incidence of AIS with osteoporosis is believed to reduce the intensity of the bone by about 20-38 percent Aim: To assess vitamin D level and BMD in patients with adolescent scoliosis. Methods: This work was done in Al-Azhar University hospitals and involved 112 patients diagnosed with AIS and a Cobb angle > 10o aged from 10 - 18 years old. Vitamin D level, Cobb angle and BMD measured in all subjects. Results: Our result included 112 patients, seventy-four (66.1%) of …
Study Of Cryptosporidium Infection In Liver Cirrhosis And Animal Model., 2021 Histology Department, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.
Study Of Cryptosporidium Infection In Liver Cirrhosis And Animal Model., Mohammed Elhussiny, Mohamed El-Faramawy
Al-Azhar International Medical Journal
Background: Cryptosporidium is a parasite that infects man especially immunocompromised patients. Liver cirrhosis reduced cellular immunity. Methods were used for diagnosis of cryptosporidium including coproscopy and copro-nested (copro-n) PCR assay. Objective: Detection of the molecular and genotypic prevalence of Cryptosporidium species in fecal samples of Egyptian patients with cirrhotic liver and exploring the possibility of association between Cryptosporidium and grades of liver cirrhosis, besides assessment their histopathological changes. Materials and Methods: This cross-sectional study was carried out on 60 patients with chronic liver disease (HCV and HBV positive) classified according to Child-Pugh score and 60 subjects free of any known …
Misoprostol Versus Letrozol With Misoprostol In Management Of First Trimesteric Missed Miscarriage, 2021 Obstetrics and Gynaecology, Luxor General Hospital, Egypt
Misoprostol Versus Letrozol With Misoprostol In Management Of First Trimesteric Missed Miscarriage, Abd Elazeem Afifi, Farid Hassan, Mofeed Mohammed
Al-Azhar International Medical Journal
Background and objective: The objective of this work is to match the security and effectiveness of two treatment modalities (Misoprostol versus Letrozol with Misoprostol) in medical treatment of 1st trimesteric missed miscarriages. Methods: This is an interventional randomized case-control investigation that was performed at the outpatient antenatal care clinic of Luxor General Hospital during the period from February to December 2017. The study included a number of 200 cases who have been randomly classified to 2 equal groups: Group-I "Misoprostol" which included 100 cases received 800-mg of misoprostol vaginally at once of diagnosis and group-II "Letrozol + Misoprostol" which included …
Assessing Early Use And Complications Of Gastrostomy Blended Feeds., 2021 Children's Mercy Hospital
Assessing Early Use And Complications Of Gastrostomy Blended Feeds., James Fraser, Kristen L. Sayers, Amy L. Pierce, Beth A. Orrick, Wendy Jo Svetanoff, Tolulope A. Oyetunji Md Mph, Shawn D. St Peter
Posters
Providers are hesitant to recommend using blended tube feeds (BF) after gastrostomy tube (GT) placement due to increased risk of bacterial contamination, nutrition inadequacy, tube blockages, and lack of data addressing clinical outcomes. Caregivers often feel that BF are more natural, better tolerated, and more cost-effective. We studied early use of BF, potential complications, and satisfaction among caregivers.
Short And Long Term Outcomes Of Using Cryoablation For Post-Operative Pain Control In Patients After Pectus Excavatum Repair, 2021 Children's Mercy Hospital
Short And Long Term Outcomes Of Using Cryoablation For Post-Operative Pain Control In Patients After Pectus Excavatum Repair, James Fraser, Kayla B. Briggs, Wendy Jo Svetanoff, David Juang, Pablo Aguayo, Jason D. Fraser, Charles L. Snyder, Tolulope A. Oyetunji, Shawn D. St. Peter Md
Posters
Background: Previous prospective trials have demonstrated that intercostal cryoablation reduces length of stay and postoperative opioid consumption compared with thoracic epidural and patient controlled analgesia (PCA) modalities. We report the findings of a 3-year prospective, observational study to elucidate long-term pain control, symptoms, and complications with attention to postoperative short and long-term pain control associated with the cryoablation technique.
Methods: Following IRB approval, we prospectively collected data on patients who underwent bar placement for pectus excavatum with thoracoscopic intercostal cryoablation by six surgeons at our institution from 2017 to 2021. Patients and their parents completed surveys regarding pain scores, narcotic …
Racial Disparities In Testicular Torsion, 2021 Children's Mercy Hospital
Racial Disparities In Testicular Torsion, Kayla B. Briggs, Obiyo O. Osuchukwu, Chris E. Roberts, James Fraser, Wendy Jo Svetanoff, Tolulope A. Oyetunji, Hanna Alemayehu
Posters
Racial Disparities in Testicular Torsion Introduction: Testicular torsion (TT) is a surgical emergency requiring prompt intervention to preserve testicular function. Race and insurance status are thought to be associated with higher rates of gonadal loss; however, reports in the literature are conflicting. We sought to determine the effect of race on the treatment and outcomes of testicular torsion. Methods: Following IRB approval, a retrospective review was conducted of patients <18 years of age who presented to 2 institutions (hereby referred to as H1 and H2) with acute scrotal pain between December 2017 and September 2019. Demographic data, clinical history, imaging results, diagnosis, and surgical outcomes were recorded. Social vulnerability index (SVI), as determined by zip code, was obtained from the Centers for Disease Control and dichotomized using the 75th percentile. Higher SVI denotes increased social vulnerability. Primary outcome was diagnosis of TT. Secondary outcomes included orchiectomy rates. A p-value <0.05 was considered significant. Results: A total of 515 patients (H1 85%, H2 15%) were included in the final analysis. There were no difference in median age, BMI, TT diagnosis and orchiectomy rate between the two institutions. H2 treated more black patients (43% vs. 14%, p=<0.01) and patients with public insurance (57% vs. 41%, p=0.03) compared to H1. In multivariate analysis, older age was associated with TT (median age TT 14.12 years [12.13,15.69]) vs. no TT 9.86 years [5,13.05], OR 1.35, 95% CI 1.18-1.55, p=<0.01). Black patients were ~4 times more likely (OR 4.05, 95% CI 2.13-7.69, p=<0.01) than white patients to be diagnosed with TT when controlled for dichotomized SVI, insurance, and age. In the same model, Hispanic patients were ~2 times more likely (OR 2.20, 95% CI 1.10-4.40, p=0.03) to be diagnosed with TT when compared to white patients. Despite more black and Hispanic patients having dichotomized SVI >75th percentile than white patients (70% and 82%, respectively vs. 16%, p=<0.01), dichotomized SVI was not found to be associated with higher rates of TT or orchiectomy, respectively. Conclusion: At the two centers, more black and Hispanic children had SVI >75th percentile, however, when controlling for this in multivariate analysis, they were significant more likely to be diagnosed with …0.01),>18>
Endovascular Thrombectomy In Patients With Large Core Ischemic Stroke: A Cost-Effectiveness Analysis From The Select Study, 2021 The University of Texas Rio Grande Valley
Endovascular Thrombectomy In Patients With Large Core Ischemic Stroke: A Cost-Effectiveness Analysis From The Select Study, Amrou Sarraj, Elena Pizzo, Kyriakos Lobotesis, James C. Grotta, Ameer E. Hassan, Michael G. Abraham, Spiros Blackburn, Arthur L. Day, Mark J. Dannenbaum, William Hicks
School of Medicine Publications and Presentations
Background It is unknown whether endovascular thrombectomy (EVT) is cost effective in large ischemic core infarcts.
Methods In the prospective, multicenter, cohort study of imaging selection study (SELECT), large core was defined as computed tomography (CT) ASPECTS(CTP) ischemic core volume (rCBF
Results From 361 patients enrolled in SELECT, 105 had large core on CT or CTP (EVT 62, MM 43). 19 (31%) EVT vs 6 (14%) MM patients achieved modified Rankin Scale (mRS) score 0–2 (OR 3.27, 95% CI 1.11 to 9.62, P=0.03) with a shift towards better mRS (cOR 2.12, 95% CI 1.05 to 4.31, P=0.04). Over the projected …
No Effect Of Hypercholesterolemia On Elastase-Induced Experimental Abdominal Aortic Aneurysm Progression, 2021 Stanford University
No Effect Of Hypercholesterolemia On Elastase-Induced Experimental Abdominal Aortic Aneurysm Progression, Toru Ikezoe, Takahiro Shoji, Jia Guo, Fanru Shen, Hong S. Lu, Alan Daugherty, Masao Nunokawa, Hiroshi Kubota, Masaaki Miyata, Baohui Xu, Ronald L. Dalman
Saha Cardiovascular Research Center Faculty Publications
Objective: Epidemiological studies link hyperlipidemia with increased risk for abdominal aortic aneurysms (AAAs). However, the influence of lipid-lowering drugs statins on prevalence and progression of clinical and experimental AAAs varies between reports, engendering controversy on the association of hyperlipidemia with AAA disease. This study investigated the impact of hypercholesterolemia on elastase-induced experimental AAAs in mice. Methods: Both spontaneous (targeted deletion of apolipoprotein E) and induced mouse hypercholesterolemia models were employed. In male wild type (WT) C57BL/6J mice, hypercholesterolemia was induced via intraperitoneal injection of an adeno-associated virus (AAV) encoding a gain-of-function proprotein convertase subtilisin/kexin type 9 mutation (PCSK9) followed by …
Management Of Coincident Pituitary Macroadenoma And Cavernous Carotid Aneurysm: A Systematic Literature Review., 2021 Thomas Jefferson University
Management Of Coincident Pituitary Macroadenoma And Cavernous Carotid Aneurysm: A Systematic Literature Review., Keenan J. Piper, Michael Karsy, Blair Barton, Mindy Rabinowitz, Marc R. Rosen, Gurston G. Nyquist, James J. Evans, Stavropoula Tjoumakaris, Christopher J. Farrell
Department of Neurosurgery Faculty Papers
Introduction
Pituitary adenomas are a common intracranial pathology with an incidence of 15 to 20% in the population while cerebral aneurysms are less common with a prevalence of 1:50 patients. The incidence of aneurysms in patients with pituitary adenoma has been estimated at 2.3 to 5.4% of patients; however, this remains unclear. Equally, the management of concomitant lesions lacks significant understanding.
Methods
A case report is presented of a concomitant cerebral aneurysm and pituitary adenoma managed by minimally invasive endovascular and endoscopic methods, respectively. A systematic review of the literature for terms "pituitary adenoma" and "aneurysm" yielded 494 studies that …
Cardiac Tamponade On Ecpella: A Case Report Of A Unique Hemodynamic Picture, 2021 Indiana University, Indianapolis
Cardiac Tamponade On Ecpella: A Case Report Of A Unique Hemodynamic Picture, Naveed Akhtar, Parth Savsani, Maya Guglin, Roopa Rao
The VAD Journal
Extracorporeal membrane oxygenation is rapidly becoming a preferred therapy for short-term hemodynamic support in cardiogenic shock, along with the use of devices such as Impella (Abiomed, Andover, MA). The two together can create unique hemodynamics resulting in altered presentation of common hemodynamic conditions such as tamponade. We present a case of a patient with fulminant myocarditis requiring veno-arterial extracorporeal membrane oxygenation and Impella support. The patient later developed a pericardial effusion with atypical tamponade physiology which masked the left ventricular systolic function recovery. We further highlight the complex hemodynamics of cardiac tamponade in patients with such mechanical circulatory support and …
Current Evidence On Potential Of Adipose Derived Stem Cells To Enhance Bone Regeneration And Future Projection, 2021 University of Virginia School of Medicine
Current Evidence On Potential Of Adipose Derived Stem Cells To Enhance Bone Regeneration And Future Projection, Quang Le, Vedavathi Madhu, Joseph M Hart, Charles R Farber, Eli R Zunder, Abhijit S Dighe, Quanjun Cui
Department of Orthopaedic Surgery Faculty Papers
Injuries to the postnatal skeleton are naturally repaired through successive steps involving specific cell types in a process collectively termed “bone regeneration”. Although complex, bone regeneration occurs through a series of well-orchestrated stages wherein endogenous bone stem cells play a central role. In most situations, bone regeneration is successful; however, there are instances when it fails and creates non-healing injuries or fracture nonunion requiring surgical or therapeutic interventions. Transplantation of adult or mesenchymal stem cells (MSCs) defined by the International Society for Cell and Gene Therapy (ISCT) as CD105+-CD90+CD73+CD45-CD34-CD14orCD11b-CD79αorCD19-HLA-DR-is being investigated as an attractive therapy for bone regeneration throughout the …
Nursing Management Of The Bloodless Surgery Patient, 2021 Lehigh Valley Health Network
Nursing Management Of The Bloodless Surgery Patient, Tiffany Achenbach Msn, Rn, Cmsrn
Posters
No abstract provided.
Neurotensin Regulates Proliferation And Stem Cell Function In The Small Intestine In A Nutrient-Dependent Manner, 2021 University of Kentucky
Neurotensin Regulates Proliferation And Stem Cell Function In The Small Intestine In A Nutrient-Dependent Manner, Stephanie A. Rock, Kai Jiang, Yuanyuan Wu, Yajuan Liu, Jing Li, Heidi L. Weiss, Chi Wang, Jianhang Jia, Tianyan Gao, B. Mark Evers
Surgery Faculty Publications
BACKGROUND & AIMS: Intestinal stem cells (ISCs) are sensitive to dietary alterations and nutrient availability. Neurotensin (NT), a gut peptide localized predominantly to the small bowel and released by fat ingestion, stimulates the growth of intestinal mucosa under basal conditions and during periods of nutrient deprivation, suggesting a possible role for NT on ISC function.
METHODS: Leucine-rich repeat-containing G-protein coupled receptor 5-Enhanced Green Fluorescent Protein (Lgr5-EGFP) NT wild type (Nt+/+) and Lgr5-EGFP NT knockout (Nt-/-) mice were fed ad libitum or fasted for 48 hours. Small intestine tissue and crypts were examined by gene …
The First Three Procedures That Marked The Dawn Of Surgery, 2021 None
The First Three Procedures That Marked The Dawn Of Surgery, Lois Hamlin
Journal of Perioperative Nursing
Archeological studies reveal that humans splinted fractures and operated on skulls. Other than dealing with wounds or fractures, early surgeons carried out three types of operative procedures – circumcision, trephination and lithotomy. The first two procedures are the most ancient, for it is hypothesised they were undertaken between 10 000 and 15 000 years ago. Circumcision was a religious, fertility or initiation rite or ritual and trephination was done for mystical as well as therapeutic purposes. In contrast, lithotomy commenced much later, between the 4th and 5th centuries BCE and therefore did not occur prehistorically. However, it is the first …
Nsg-Pro Mouse Model For Uncovering Resistance Mechanisms And Unique Vulnerabilities In Human Luminal Breast Cancers, 2021 Medical College of Wisconsin
Nsg-Pro Mouse Model For Uncovering Resistance Mechanisms And Unique Vulnerabilities In Human Luminal Breast Cancers, Yunguang Sun, Ning Yang, Fransiscus E Utama, Sameer S Udhane, Junling Zhang, Amy R Peck, Alicia Yanac, Katherine Duffey, John F Langenheim, Vindhya Udhane, Guanjun Xia, Jess F Peterson, Julie M Jorns, Marja T Nevalainen, Romain Rouet, Peter Schofield, Daniel Christ, Christopher J Ormandy, Anne Rosenberg, I Chervoneva, Shirng-Wern Tsaih, Michael J Flister, Serge Y Fuchs, Kay-Uwe Wagner, Hallgeir Rui
Department of Surgery Faculty Papers
Most breast cancer deaths are caused by estrogen receptor-α-positive (ER+) disease. Preclinical progress is hampered by a shortage of therapy-naïve ER+ tumor models that recapitulate metastatic progression and clinically relevant therapy resistance. Human prolactin (hPRL) is a risk factor for primary and metastatic ER+ breast cancer. Because mouse prolactin fails to activate hPRL receptors, we developed a prolactin-humanized Nod-SCID-IL2Rγ (NSG) mouse (NSG-Pro) with physiological hPRL levels. Here, we show that NSG-Pro mice facilitate establishment of therapy-naïve, estrogen-dependent PDX tumors that progress to lethal metastatic disease. Preclinical trials provide first-in-mouse efficacy of pharmacological hPRL suppression on residual ER+ human breast cancer …