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Prevalence Of Common Disease Conditions In A Large Cohort Of Individuals With Down Syndrome In The United States, Brian Chicoine, Anne Rivelli, Veronica Fitzpatrick, Laura Chicoine, Gengjie Jia, Andrey Rzhetsky 2021 Advocate Aurora Health

Prevalence Of Common Disease Conditions In A Large Cohort Of Individuals With Down Syndrome In The United States, Brian Chicoine, Anne Rivelli, Veronica Fitzpatrick, Laura Chicoine, Gengjie Jia, Andrey Rzhetsky

Journal of Patient-Centered Research and Reviews

Purpose: Given the current life expectancy and number of individuals living with Down syndrome (DS), it is important to learn common occurrences of disease conditions across the developmental lifespan. This study analyzed data from a large cohort of individuals with DS in an effort to better understand these disease conditions, inform future screening practices, tailor medical care guidelines, and improve utilization of health care resources.

Methods: This retrospective, descriptive study incorporated up to 28 years of data, compiled from 6078 individuals with DS and 30,326 controls matched on age and sex. Data were abstracted from electronic medical records within ...


Non-Dental Oral Cavity Findings In Gastroesophageal Reflux Disease: A Systematic Review And Meta-Analysis, Madalina-Gabriela Indre, Darius Sampelean, Vlad Taru, Angela Cozma, Dorel Sampelean, Mircea Vasile Milaciu, Olga Hilda Orasan 2021 PROF. DR. OCTAVIAN FODOR REGIONAL INSTITUTE OF GASTROENTEROLOGY AND HEPATOLOGY, CLUJ-NAPOCA, ROMANIA

Non-Dental Oral Cavity Findings In Gastroesophageal Reflux Disease: A Systematic Review And Meta-Analysis, Madalina-Gabriela Indre, Darius Sampelean, Vlad Taru, Angela Cozma, Dorel Sampelean, Mircea Vasile Milaciu, Olga Hilda Orasan

Journal of Mind and Medical Sciences

Gastroesophageal reflux disease (GERD) is known as the most prevalent gastrointestinal disorder in the United States, leading to substantial morbidity, although associated mortality is rare. Based on the appearance of esophageal mucosa on upper endoscopy, GERD is divided into erosive esophagitis (ERD) and nonerosive reflux disease (NERD). Heartburn and acid regurgitation are the typical symptoms of the disease, although some patients may present atypical manifestations such as epigastric pain, nausea, asthma, chronic cough, pharyngitis, laryngitis, sleep disturbances, otitis, and sinusitis. Other signs, such as oral mucosal lesions may result from GERD by direct acid or acidic vapor contact in the ...


Effects Of Combining Meditation Techniques On Short-Term Memory, Attention, And Affect In Healthy College Students., Samani Unnata Pragya, Neelam D Mehta, Bassam Abomoelak, Parvin Uddin, Pushya Veeramachaneni, Naina Mehta, Stephanie Moore, Melissa Jean-Francois, Stephanie Garcia, Samani Chaitanya Pragya, Devendra I Mehta 2021 Department of Religions and Philosophies, University of London, London, United Kingdom

Effects Of Combining Meditation Techniques On Short-Term Memory, Attention, And Affect In Healthy College Students., Samani Unnata Pragya, Neelam D Mehta, Bassam Abomoelak, Parvin Uddin, Pushya Veeramachaneni, Naina Mehta, Stephanie Moore, Melissa Jean-Francois, Stephanie Garcia, Samani Chaitanya Pragya, Devendra I Mehta

Department of Medicine Faculty Papers

Meditation refers to a family of self-regulation practices that focuses on training attention and awareness to foster psycho-emotional well-being and to develop specific capacities such as calmness, clarity, and concentration. We report a prospective convenience-controlled study in which we analyzed the effect of two components of Preksha Dhyāna – buzzing bee sound meditation (Mahapran dhvani) and color meditation (leśyā dhyāna) on healthy college students. Mahapran and leśya dhyāna are two Preksha Dhyāna practices that are based on sound and green color, respectively. The study population represents a suitable target as college students experience different stress factors during the school year. This ...


Preliminary Data On The Potential For Unintentional Antidoping Rule Violations By Permitted Cannabidiol (Cbd) Use., Ute Mareck, Gregor Fusshöller, Hans Geyer, Marilyn A. Huestis, Anja B Scheiff, Mario Thevis 2021 Institute of Biochemistry, German Sport University Cologne, Cologne, Germany

Preliminary Data On The Potential For Unintentional Antidoping Rule Violations By Permitted Cannabidiol (Cbd) Use., Ute Mareck, Gregor Fusshöller, Hans Geyer, Marilyn A. Huestis, Anja B Scheiff, Mario Thevis

Institute of Emerging Health Professions Faculty Papers

According to the World Anti-Doping Agency (WADA) regulations, cannabinoids use is prohibited in competition except for cannabidiol (CBD) use. For an adverse analytical finding (AAF) in doping control, cannabinoid misuse is based on identification of the pharmacologically inactive metabolite 11-nor-delta-9-carboxy-tetrahydrocannabinol-9-carboxylic acid (carboxy-THC) in urine at a concentration greater than 180 ng/ml. All other (minor) cannabinoids are reported as AAF when identified, except for CBD that has been explicitly excluded from the class of cannabinoids on WADA's Prohibited List since 2018. However, due to the fact that CBD isolated from cannabis plants may contain additional minor cannabinoids, the permissible ...


Biomolecules As Model Indicators Of In Vitro And In Vivo Cold Plasma Safety, Caitlin Heslin, Daniela Boehm, Julianne Megaw, Brendan F. Gilmore, Theresa A. Freeman, Noreen J. Hickok, P. J. Cullen, Paula Bourke 2021 School of Food Science and Environmental Health, Technological University Dublin, Dublin, Ireland

Biomolecules As Model Indicators Of In Vitro And In Vivo Cold Plasma Safety, Caitlin Heslin, Daniela Boehm, Julianne Megaw, Brendan F. Gilmore, Theresa A. Freeman, Noreen J. Hickok, P. J. Cullen, Paula Bourke

Department of Medicine Faculty Papers

No abstract provided.


Cerrahi Tıp Bilimleri Tanı Ve Tedavi, Tolga Önder, Serhat Doğan, Yusuf Aydın, Ferhat Çay, Aytül Hande Yardımcı, Nazan Çevik 2021 Istanbul Taksim Training and Research Hospital

Cerrahi Tıp Bilimleri Tanı Ve Tedavi, Tolga Önder, Serhat Doğan, Yusuf Aydın, Ferhat Çay, Aytül Hande Yardımcı, Nazan Çevik

Health Sciences

Cerrahinin tarihinin insanlık kadar eski olduğu bilinse de en net belge Antik Yunan Dönemi’nde yaşamış olan Hipokrat’ın yazdığı ‘On The Surgery’ yani ‘Cerrahide’ (MÖ 400) kitabıdır. Bu kitapta cerrahlar karşımıza uzman olarak çıkmakta ve cerrahların yapması gerekenler, asistanları, cerrahi el aletleri ve travmalara yaklaşımlara kadar pek çok konudan bahsedilmektedir


Healthcare Policy Analysis: Next Of Kin Contact Information On Driver's Licensse And Its Use In Emergency Notification, Suzanne Sheaffer 2020 Duquesne University

Healthcare Policy Analysis: Next Of Kin Contact Information On Driver's Licensse And Its Use In Emergency Notification, Suzanne Sheaffer

Doctor of Nursing Practice (DNP) Manuscripts

Abstract

In Pennsylvania, there has been a rise in unclaimed decedents within Third-Class and Fifth-Class county coroner offices. Decreasing the number of unclaimed decedents in Third-Class and Fifth-Class Pennsylvania coroners offices is the goal for this healthcare policy analysis project. Using the Bardach’s eight step policy analysis problem solving technique, the data and the project outcomes will be presented to Pennsylvania Department of Transportation (PennDOT). Data collection began with a questionnaire sent to all 67 counties to determine who had access to the Pennsylvania driver’s license database entitled Pennsylvania Justice Network (JNET). Fourteen of 67 counties have partial ...


Needs Of Individuals Living With Hepatitis Delta Virus And Their Caregivers, 2016-2019., Priyanka Kumar, Catherine Freeland, Sierra Bodor, Sean Farrell, Chari Cohen, Rosemary Frasso PhD, MSc, CPH 2020 Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, Pennsylvania; Jefferson College of Population Health, Philadelphia, Pennsylvania

Needs Of Individuals Living With Hepatitis Delta Virus And Their Caregivers, 2016-2019., Priyanka Kumar, Catherine Freeland, Sierra Bodor, Sean Farrell, Chari Cohen, Rosemary Frasso Phd, Msc, Cph

Department of Medicine Faculty Papers

INTRODUCTION: Hepatitis delta virus (HDV) is a serious coinfection of the hepatitis B virus (HBV) that is estimated to affect between 48 to 72 million people worldwide. Data are limited on the informational needs of people living with HDV. The Hepatitis B Foundation, a US-based nonprofit organization that provides support to people living with HBV and HDV, receives emails (queries) as part of a helpline, a service to provide information, resources, and support to people affected by HBV and HDV.

METHODS: Query content was analyzed to assess the impact of HDV at the individual level. A total of 65 HDV-related ...


Evaluation Of Aging And Genetic Mutation Variants On Tauopathy, Amber M. Tetlow 2020 University of South Florida

Evaluation Of Aging And Genetic Mutation Variants On Tauopathy, Amber M. Tetlow

Graduate Theses and Dissertations

Alzheimer’s disease (AD) is characterized by amyloid β plaques and neurofibrillary tau tangles (NFTs). While research has demonstrated amyloid pathology occurs prior to tau pathology, or tauopathy, tau has proven to be more toxic. Tauopathy is associated with cognitive declines and neurodegeneration. These findings have highlighted the importance of further understanding tauopathy. In the progression of tauopathy, there is an observable immune response that can be measured by glial cells such as microglia. Activated microglia are known to exacerbate tauopathy rather than reducing the pathology. Research has indicated that with increased age there is an increased risk for AD-related ...


Urinary Acrylonitrile Metabolite Concentrations Before And After Smoked, Vaporized, And Oral Cannabis In Frequent And Occasional Cannabis Users., David L Ashley, Víctor R De Jesús, Osama A Abulseoud, Marilyn A. Huestis, Daniel F Milan, Benjamin C Blount 2020 Department of Population Health Sciences, School of Public Health, Georgia State University, Atlanta, GA 30303, United States

Urinary Acrylonitrile Metabolite Concentrations Before And After Smoked, Vaporized, And Oral Cannabis In Frequent And Occasional Cannabis Users., David L Ashley, Víctor R De Jesús, Osama A Abulseoud, Marilyn A. Huestis, Daniel F Milan, Benjamin C Blount

Institute of Emerging Health Professions Faculty Papers

Cannabis use through smoking, vaping, or ingestion is increasing, but only limited studies have investigated the resulting exposure to harmful chemicals. N-acetyl-S-(2-cyanoethyl)-L-cysteine (2CYEMA), a urinary metabolite of acrylonitrile, a possible carcinogen, is elevated in the urine of past-30-day cannabis users compared to non-cannabis users. Five frequent and five occasional cannabis users smoked and vaped cannabis on separate days; one also consumed cannabis orally. Urine samples were collected before and up to 72 h post dose and urinary 2CYEMA was quantified. We compared 2CYEMA pre-exposure levels, maximum concentration, time at maximum concentration for occasional versus frequent users following different ...


Occupational Therapy’S Role In Addressing Sex And Intimacy For Individuals With Progressive Neuromuscular Disorders, Lindsay N. Richards, Becki Cohill, Katrhyn Ellis, Susan MacDermott 2020 University of St. Augustine for Health Sciences

Occupational Therapy’S Role In Addressing Sex And Intimacy For Individuals With Progressive Neuromuscular Disorders, Lindsay N. Richards, Becki Cohill, Katrhyn Ellis, Susan Macdermott

San Marcos, Summer 2020

Individuals with progressive neuromuscular disorders (PND); specifically, Parkinson’s disease (PD), Multiple Sclerosis (MS), Huntington’s Disease (HD), and Amyotrophic Lateral Sclerosis (ALS) often face physical, psychological, and social challenges related to sex and intimacy. Occupational therapy (OT) practitioners are experts in activity analysis and are equipped with unique knowledge of performance skills and client factors to address deficits in occupational performance.

Though there is literature presenting the effects of PND on sexual occupations, a gap exists as it relates to qualitative data from the perspective of the individual and their partners. A mixed-methods survey was conducted examining the lived ...


Evaluation Of Resident Palpation Skills In Foot And Ankle Anatomic Structures Using Bedside Ultrasound, Se Won Lee, Phuong U. Le, Craig Van Dien, Mike Hansen, Timothy Tiu 2020 MountainView Hospital

Evaluation Of Resident Palpation Skills In Foot And Ankle Anatomic Structures Using Bedside Ultrasound, Se Won Lee, Phuong U. Le, Craig Van Dien, Mike Hansen, Timothy Tiu

HCA Healthcare Journal of Medicine

Objective: The objective is to determine the accuracy of foot and ankle joint and soft tissue structure palpation in Physical Medicine and Rehabilitation (PM&R) residents using ultrasonography (US) verification.

Methods: PM&R residents were tested in an outpatient musculoskeletal (MSK) clinic on palpated foot and ankle anatomic structures in a human model. Once the presumed structures were localized, residents marked a 1 cm size circle on the overlying skin with a ink marker. The accuracy of the circle over the joint line and soft tissue structures was verified using US.

Results: The overall palpation accuracy for 22 joint line ...


Injury Prevention Among Professional Ballet Dancers – A Qualitative Study, Elizabeth Balyakina DO, Nathan J. Hershberger DO, Sajid A. Surve, Rita M. Patterson 2020 HCA Healthcare

Injury Prevention Among Professional Ballet Dancers – A Qualitative Study, Elizabeth Balyakina Do, Nathan J. Hershberger Do, Sajid A. Surve, Rita M. Patterson

Neuromusculoskeletal

Rationale: The physical stress placed on ballet dancers’ bodies during their professional career predisposes them to injury. Qualitative research can be used to examine ways to support current strategies that dancers use to stay healthy and to inform further research in areas where dancers may be most prone to injury.

Purpose: To examine therapies and strategies dancers use to keep healthy and to treat injury.

Educational Objectives:

At the end of the presentation, the participants will be able to:

  1. Describe the most common strategies dancers use to stay healthy
  2. Formulate an understanding of how professional dancers manage injury
  3. Identify the ...


The Rice Pentatricopeptide Repeat Protein Ppr756 Is Involved In Pollen Development By Affecting Multiple Rna Editing In Mitochondria., Qiannan Zhang, Yanghong Xu, Jishuai Huang, Kai Zhang, Haijun Xiao, Xiaojian Qin, Linlin Zhu, Yingguo Zhu, Jun Hu 2020 State Key Laboratory of Hybrid Rice, Engineering Research Center for Plant Biotechnology and Germplasm Utilization of Ministry of Education, College of Life Sciences, Wuhan University, Wuhan, China

The Rice Pentatricopeptide Repeat Protein Ppr756 Is Involved In Pollen Development By Affecting Multiple Rna Editing In Mitochondria., Qiannan Zhang, Yanghong Xu, Jishuai Huang, Kai Zhang, Haijun Xiao, Xiaojian Qin, Linlin Zhu, Yingguo Zhu, Jun Hu

Department of Medicine Faculty Papers

In land plants, the pentatricopeptide repeat (PPR) proteins form a large family involved in post-transcriptional processing of RNA in mitochondria and chloroplasts, which is critical for plant development and evolutionary adaption. Although studies showed a number of PPR proteins generally influence the editing of organellar genes, few of them were characterized in detail in rice. Here, we report a PLS-E subclass PPR protein in rice, PPR756, loss of function of which led to the abolishment of RNA editing events among three mitochondrial genes including


Effects Of Occupational Therapy Intervention In Low Vision, Zach Harrington, Juliana Crossett, Carlie Carter, Baleigh Gooch, Liberty Harris 2020 University of Tennessee Health Science Center

Effects Of Occupational Therapy Intervention In Low Vision, Zach Harrington, Juliana Crossett, Carlie Carter, Baleigh Gooch, Liberty Harris

Master of Occupational Therapy Student Critically Appraised Topics

The purpose of this CAT is to investigate therapeutic intervention and its effects for improving independence in occupational performance, overall health, quality of life, and mental health in adults over 40 with acquired low vision. This CAT contains nine peer-reviewed research articles from national journals. Study designs include one randomized controlled trial, seven systematic reviews, and one non-randomized controlled trial. All studies relate directly to the components of our evidence-based practice question and will be used to support further research on the optometry and occupational therapy collaboration. All of the articles specifically describe various interventions used in the low vision ...


Medical Student Understanding Of The Pm&R Specialty, Disability, And Post-Acute Care, Stephanie Tow 2020 Children's Mercy Kansas City

Medical Student Understanding Of The Pm&R Specialty, Disability, And Post-Acute Care, Stephanie Tow

Research Days

No abstract provided.


Reduced Length Of Stay In Major Hepatectomy Surgery After Implementation Of An Enhanced Recovery Pathway In The United States Veteran Population, Yvonne Nguyen MD, Marilyn McNulty NP, Leopoldo Fernandez MD, Michael R. Kazior MD 2020 Virginia Commonwealth University

Reduced Length Of Stay In Major Hepatectomy Surgery After Implementation Of An Enhanced Recovery Pathway In The United States Veteran Population, Yvonne Nguyen Md, Marilyn Mcnulty Np, Leopoldo Fernandez Md, Michael R. Kazior Md

Graduate Medical Education (GME) Resident and Fellow Research Day Posters

Introduction

Enhanced recovery after surgery (ERAS) pathways are associated with better postoperative recovery, however, evidence is lacking in major liver surgery, .This study aimed to evaluate the impact of an ERAS pathway in U.S. veterans undergoing major hepatectomy surgery. We hypothesized that the adoption of an ERAS pathway reduces decreased length of stay (LOS).

Methods

After approval from the Hunter Holmes McGuire VA Medical Center IRB, we compared data from consecutive patients undergoing elective open hepatectomy within an ERAS pathway (January 2019-December 2019) to a previous cohort of patients before introduction of ERAS (July 2016-December 2017). One surgeon performed ...


What’S That Beeping Sound? Case Report, Ellie Balakhanlou MD, Olivier Rolin MD, Eugenio Monasterio 2020 Department of Physical Medicine and Rehabilitation, Virginia Commonwealth University Health System

What’S That Beeping Sound? Case Report, Ellie Balakhanlou Md, Olivier Rolin Md, Eugenio Monasterio

Graduate Medical Education (GME) Resident and Fellow Research Day Posters

Abstract Title: What’s that Beeping Sound? A Case Report

Ellie Balakhanlou, Medical Doctor - Medical Resident, Virginia Commonwealth University School of Medicine (Role: Presenting Author)

Olivier Rolin, Medical Doctor – Assistant Professor, Virginia Commonwealth University School of Medicine (Role: Corresponding Author)

Eugenio Monasterio, Medical Doctor – Assistant Professor, Virginia Commonwealth University School of Medicine (Role: Corresponding Author)

Disclosure: None. Setting: Outpatient pediatric clinic Patient: A 21 year old female with spastic quadriplegic cerebral palsy (CP) with an intrathecal baclofen (ITB) pump

Case Description:

The patient presented with concerns of intermittent beeping sounds from her pump. She does not endorse any new weakness ...


Chronic Post-Surgical Abdominal Pain Treated With Percutaneous Peripheral Nerve Stimulation Of Iliohypogastric And Ilioinguinal Nerves, Harnek Bajaj, Denise Lester 2020 VCU Health System

Chronic Post-Surgical Abdominal Pain Treated With Percutaneous Peripheral Nerve Stimulation Of Iliohypogastric And Ilioinguinal Nerves, Harnek Bajaj, Denise Lester

Graduate Medical Education (GME) Resident and Fellow Research Day Posters

Chronic pelvic and lower abdominal pain can be a severely debilitating condition that affects between 7% to 24% of the general population (4). The anterior rami of L1 and T12 give contributions to the ilioinguinal and iliohypogastric nerves which provide sensory innervation to the lower abdomen and pubic regions (3). Entrapment or damage of these nerves can occur due to a variety of mechanisms, and common treatment options have included medications (2), nerve blocks (1), and in rare cases, surgical resection of the involved nerve. In this case, a 47 year old morbidly obese female with history of chronic left ...


Getting On The Same Page: A Quality Improvement Project To Reduce Overnight Nursing-To-Resident Physician Pages In An Inpatient Rehabilitation Unit, Renae Fisher MD, Rajbir Chaggar MD, Anthony Zenger MD, Susan Hamilton RN, BSN, William Carter MD 2020 VCU

Getting On The Same Page: A Quality Improvement Project To Reduce Overnight Nursing-To-Resident Physician Pages In An Inpatient Rehabilitation Unit, Renae Fisher Md, Rajbir Chaggar Md, Anthony Zenger Md, Susan Hamilton Rn, Bsn, William Carter Md

Graduate Medical Education (GME) Resident and Fellow Research Day Posters

Introduction
Many Physical Medicine and Rehabilitation (PM&R) residency programs utilize “home call” systems for nighttime coverage of inpatient services. In this system, trainees are expected to work at full capacity the following day after taking nocturnal call. While “on call,” trainees receive both urgent and non-urgent pages throughout the night, which disrupt sleep. To mitigate fatigue, improve hand-offs and improve timing of patient care, this study targeted reducing non-urgent overnight pages from nurses to home call PM&R residents between 11pm to 6am.

Methods

We implemented a prospective quality improvement study with interventions including holding “Getting on the Same ...


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