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Enhancing Family Communication In Families Where A Parent Has A Mental Illness, Scott Yates, Lina Gatsou 2017 School of Applied Social Sciences, De Montfort University

Enhancing Family Communication In Families Where A Parent Has A Mental Illness, Scott Yates, Lina Gatsou

Journal of Parent and Family Mental Health

In this brief we will discuss the Think Family-Whole Family Programme, which differs from other interventions by putting a central focus on fostering effective communication within families. This can enhance families’ understanding of parental mental illness (PMI) and how it affects behavior and relationships, help families jointly set goals for recovery, and enable more supportive interactions among family members.


Improving Detection Of Mental Health Problems In Community Settings In Nepal: Development And Pilot Testing Of The Community Informant Detection Tool, Prasansa Subba, Nagendra P. Luitel, Brandon A. Kohrt, Mark Jordans 2017 George Washington University

Improving Detection Of Mental Health Problems In Community Settings In Nepal: Development And Pilot Testing Of The Community Informant Detection Tool, Prasansa Subba, Nagendra P. Luitel, Brandon A. Kohrt, Mark Jordans

Psychiatry and Behavioral Sciences Faculty Publications

Background

Despite increasing efforts to expand availability of mental health services throughout the world, there continues to be limited utilization of these services by persons with mental illness and their families. Community-based detection that facilitates identification and referral of people with mental health problems has been advocated as an effective strategy to increase help-seeking and service utilization. The Community Informant Detection Tool (CIDT) was developed for the community informants to identify people with depression, psychosis, alcohol use problems, epilepsy, and child behavioral problems in community settings. The CIDT has been validated in Nepal and found to be effective in promoting ...


A 6-Month Open-Label Extension Study Of Vortioxetine In Pediatric Patients With Depressive Or Anxiety Disorders., Robert L Findling, Adelaide S Robb, Melissa P DelBello, Michael Huss, Nora K McNamara, Elias H Sarkis, Russell E Scheffer, Lis H Poulsen, Grace Chen, Ole M Lemming, Philippe Auby 2017 George Washington University

A 6-Month Open-Label Extension Study Of Vortioxetine In Pediatric Patients With Depressive Or Anxiety Disorders., Robert L Findling, Adelaide S Robb, Melissa P Delbello, Michael Huss, Nora K Mcnamara, Elias H Sarkis, Russell E Scheffer, Lis H Poulsen, Grace Chen, Ole M Lemming, Philippe Auby

Psychiatry and Behavioral Sciences Faculty Publications

OBJECTIVES: In this 6-month open-label extension (OLE) of NCT01491035 (a 14-day, open-label, pharmacokinetic/safety lead-in study), the long-term safety and tolerability of vortioxetine (5-20 mg/day) were investigated in children and adolescents with a DSM-IV-TR™ diagnosis of depressive or anxiety disorder in the United States or Germany. The study also was designed to provide data to inform dose selection and titration in future pediatric studies with vortioxetine.

METHODS: Safety evaluations included spontaneously reported adverse events (AEs), the Columbia Suicide Severity Rating Scale (C-SSRS), and the Pediatric Adverse Events Rating Scale (PAERS; clinician administered). Clinical effectiveness was determined by Clinical Global ...


Finasteride As A Model For Personalized Medicine, Ion G. Motofei, David L. Rowland, Ioana Păunică, Octavian C. Tănăsescu, Petrişor Banu, Stana Păunică 2017 Carol Davila University, Faculty of General Medicine, Bucharest, Romania

Finasteride As A Model For Personalized Medicine, Ion G. Motofei, David L. Rowland, Ioana Păunică, Octavian C. Tănăsescu, Petrişor Banu, Stana Păunică

Journal of Mind and Medical Sciences

The side effects of Finasteride are currently a subject of controversy. Some studies report minor or acceptable adverse effects, which decrease after a variable period of time so that they do not necessitate terminating Finasteride administration. However, several clinical and neuro-endocrine studies show that some adverse effects persist indefinitely in the form of post-Finasteride syndrome, even after the drug cessation. This paper presents a possible explanation for these inconsistent findings. First, the study design of either informing or not informing patients prior therapy about possible adverse effects can influence the incidence and magnitude of reported adverse effects. Second, structural and ...


End-Stage Head And Neck Cancer: Coping Mechanism, Bogdan Popescu, Oana Paun, Razvan V. Scăunaşu, Serban V.G. Berteşteanu 2017 Carol Davila University, Department of Otorhinolaryngology, Colțea Clinical Hospital, Bucharest, Romania

End-Stage Head And Neck Cancer: Coping Mechanism, Bogdan Popescu, Oana Paun, Razvan V. Scăunaşu, Serban V.G. Berteşteanu

Journal of Mind and Medical Sciences

Coping mechanisms are patients’ means of adapting to stressful situations and involve psychological and physical changes in behavior. Patients adapt to head and neck cancer in a variety of ways. Head and neck cancers are extremely debilitating, especially in advanced stages of the disease or in end-of-life situations. While an oncology team needs to address the needs of all oncology patients, the advanced terminal patients require special attention. Most of these patients do not cope well with their situation and have a tendency to cease social interactions. Pain is the most frequentlyexperienced medical disability in patients having an end-stage illness ...


Supporting The Education Of Young Adults With Serious Mental Health Conditions: Part 2: State Of The Practice, Michelle Mullen, Kathleen Biebel, Marsha Langer Ellison 2017 Rutgers University

Supporting The Education Of Young Adults With Serious Mental Health Conditions: Part 2: State Of The Practice, Michelle Mullen, Kathleen Biebel, Marsha Langer Ellison

Kathleen Biebel

The majority of college students with serious mental health conditions (SMHC) do not finish school, jeopardizing their long-term employment. Can supported education services help? Marsha Ellison, Michelle Mullen and Kathleen Biebel, researchers and trainers of supported education services, hosted a 2-part webinar series presenting the state of the science of the practice of supported education and related strategies for achieving post-secondary education goals of young adults with SMHC. What are the education support needs of youth and young adults with mental health conditions? What are the practices and services that meet those needs? Part 1 - State of the Science is ...


Supporting The Education Of Young Adults With Serious Mental Health Conditions: State Of The Science & Practice, Marsha Langer Ellison, Michelle Mullen, Kathleen Biebel 2017 University of Massachusetts Medical School

Supporting The Education Of Young Adults With Serious Mental Health Conditions: State Of The Science & Practice, Marsha Langer Ellison, Michelle Mullen, Kathleen Biebel

Kathleen Biebel

The majority of college students with serious mental health conditions (SMHC) do not finish school, jeopardizing their long-term employment. Can supported education services help? Marsha Ellison, Michelle Mullen and Kathleen Biebel, researchers and trainers of supported education services, hosted a 2-part webinar series presenting the state of the science of the practice of supported education and related strategies for achieving post-secondary education goals of young adults with SMHC. What is supported education? Why is it important? What is the evidence? Part 2: State of the Practice is also available.


Supporting The Education Of Young Adults With Serious Mental Health Conditions: State Of The Science & Practice, Marsha Langer Ellison, Michelle Mullen, Kathleen Biebel 2017 University of Massachusetts Medical School

Supporting The Education Of Young Adults With Serious Mental Health Conditions: State Of The Science & Practice, Marsha Langer Ellison, Michelle Mullen, Kathleen Biebel

Marsha Langer Ellison

The majority of college students with serious mental health conditions (SMHC) do not finish school, jeopardizing their long-term employment. Can supported education services help? Marsha Ellison, Michelle Mullen and Kathleen Biebel, researchers and trainers of supported education services, hosted a 2-part webinar series presenting the state of the science of the practice of supported education and related strategies for achieving post-secondary education goals of young adults with SMHC.

  • What is supported education?
  • Why is it important?
  • What is the evidence?

Part 2: State of the Practice is also available.


Supporting The Education Of Young Adults With Serious Mental Health Conditions: Part 2: State Of The Practice, Michelle Mullen, Kathleen Biebel, Marsha Langer Ellison 2017 Rutgers University

Supporting The Education Of Young Adults With Serious Mental Health Conditions: Part 2: State Of The Practice, Michelle Mullen, Kathleen Biebel, Marsha Langer Ellison

Marsha Langer Ellison

The majority of college students with serious mental health conditions (SMHC) do not finish school, jeopardizing their long-term employment. Can supported education services help? Marsha Ellison, Michelle Mullen and Kathleen Biebel, researchers and trainers of supported education services, hosted a 2-part webinar series presenting the state of the science of the practice of supported education and related strategies for achieving post-secondary education goals of young adults with SMHC. What are the education support needs of youth and young adults with mental health conditions? What are the practices and services that meet those needs? Part 1 - State of the Science is ...


Adapting Ips For Young Adults: The Threshold Study, Marsha Langer Ellison, Vanessa Vorhies Klodnick, Gary R. Bond 2017 University of Massachusetts Medical School

Adapting Ips For Young Adults: The Threshold Study, Marsha Langer Ellison, Vanessa Vorhies Klodnick, Gary R. Bond

Marsha Langer Ellison

This webinar describes the "Adapting Individual Placement Support (IPS) for Young Adults: The Thresholds study." The mission of the Transitions RTC is to improve the supports for youth and young adults, ages 14-30, with serious mental health conditions who are trying to successfully complete their schooling and training and move into rewarding work lives. The project with Thresholds tested a peer mentoring model for young people with serious mental health conditions who are working and going to school.


The Relationship Between Self-Reported Borderline Personality Features And Prospective Illness Course In Bipolar Disorder., Georg Riemann, Nadine Weisscher, Robert M Post, Lori Altshuler, Susan McElroy, Marc A Frye, Paul E Keck, Gabriele S Leverich, Trisha Suppes, Heinz Grunze, Willem A Nolen, Ralph W Kupka 2017 George Washington University

The Relationship Between Self-Reported Borderline Personality Features And Prospective Illness Course In Bipolar Disorder., Georg Riemann, Nadine Weisscher, Robert M Post, Lori Altshuler, Susan Mcelroy, Marc A Frye, Paul E Keck, Gabriele S Leverich, Trisha Suppes, Heinz Grunze, Willem A Nolen, Ralph W Kupka

Psychiatry and Behavioral Sciences Faculty Publications

Background

Although bipolar disorder (BD) and borderline personality disorder (BPD) share clinical characteristics and frequently co-occur, their interrelationship is controversial. Especially, the differentiation of rapid cycling BD and BPD can be troublesome. This study investigates the relationship between borderline personality features (BPF) and prospective illness course in patients with BD, and explores the effects of current mood state on self-reported BPF profiles.

Methods

The study included 375 patients who participated in the former Stanley Foundation Bipolar Network. All patients met DSM-IV criteria for bipolar-I disorder (n = 294), bipolar-II disorder (n = 72) or bipolar disorder NOS (n = 9). BPF were assessed ...


The Family Model, Adrian Falkov 2017 Westmead Hospital, Sydney, Australia

The Family Model, Adrian Falkov

Journal of Parent and Family Mental Health

The Family Model provides clinicians and managers with a brief, accessible, and practical approach that supports collaborative ways of working with individuals and their families in which one or more members experience mental illness. It can be used as a tool to foster engagement and facilitate thought about connections between symptoms and relationships, while highlighting a family’s strengths and difficulties.


Cortical Activation During Action Observation, Action Execution, And Interpersonal Synchrony In Adults: A Functional Near-Infrared Spectroscopy (Fnirs) Study, Anjana Bhat, Michael Hoffman, Susanna Trost, Mckenzie Culotta, Jeffrey Eilbott, Daisuke Tsuzuki, Kevin A. Pelphrey 2017 George Washington University

Cortical Activation During Action Observation, Action Execution, And Interpersonal Synchrony In Adults: A Functional Near-Infrared Spectroscopy (Fnirs) Study, Anjana Bhat, Michael Hoffman, Susanna Trost, Mckenzie Culotta, Jeffrey Eilbott, Daisuke Tsuzuki, Kevin A. Pelphrey

Psychiatry and Behavioral Sciences Faculty Publications

Introduction: Humans engage in Interpersonal Synchrony (IPS) as they synchronize their own actions with that of a social partner over time. When humans engage in imitation/IPS behaviors, multiple regions in the frontal, temporal, and parietal cortices are activated including the putative Mirror Neuron Systems (Iacoboni, 2005; Buxbaum et al., 2014). In the present study, we compared fNIRS-based cortical activation patterns across three conditions of action observation (“Watch” partner), action execution (“Do” on your own), and IPS (move “Together”).

Methods: Fifteen typically developing adults completed a reach and cleanup task with the right arm while cortical activation was examined using ...


Implementing An Online Health Information Platform For People With Serious Mental Illness, Zlatina Kostova, Len L. Levin, Mahima Sindhu, Joanne Nicholson, Kathleen Biebel, Elaine R. Martin 2017 University of Massachusetts Medical School

Implementing An Online Health Information Platform For People With Serious Mental Illness, Zlatina Kostova, Len L. Levin, Mahima Sindhu, Joanne Nicholson, Kathleen Biebel, Elaine R. Martin

Kathleen Biebel

Introduction: Individuals with serious mental illness (SMI) die, on average, 25 years earlier than the general population. Higher rates of smoking, alcohol consumption, poor nutrition, lack of physical activity, obesity, lack of preventive healthcare, and other modifiable risk factors, as well as side effects associated with certain antipsychotic medications, place individuals with SMI at high physical health risk. They are designated a health disparity population by the US National Association of State Mental Health Program Directors and as a vulnerable group worldwide by the World Health Organization. While the Internet provides intriguing opportunities to support person-centered health care, web-based resources ...


Implementing An Online Health Information Platform For People With Serious Mental Illness, Zlatina Kostova, Len L. Levin, Mahima Sindhu, Joanne Nicholson, Kathleen Biebel, Elaine R. Martin 2017 University of Massachusetts Medical School

Implementing An Online Health Information Platform For People With Serious Mental Illness, Zlatina Kostova, Len L. Levin, Mahima Sindhu, Joanne Nicholson, Kathleen Biebel, Elaine R. Martin

Library Publications and Presentations

Introduction: Individuals with serious mental illness (SMI) die, on average, 25 years earlier than the general population. Higher rates of smoking, alcohol consumption, poor nutrition, lack of physical activity, obesity, lack of preventive healthcare, and other modifiable risk factors, as well as side effects associated with certain antipsychotic medications, place individuals with SMI at high physical health risk. They are designated a health disparity population by the US National Association of State Mental Health Program Directors and as a vulnerable group worldwide by the World Health Organization. While the Internet provides intriguing opportunities to support person-centered health care, web-based resources ...


Comparison Of Characteristics Among Korean American Male Smokers Between Survey And Cessation Studies, Sun S. Kim, Seongho Kim, Colleen E. McKay, Douglas M. Ziedonis 2017 University of Massachusetts Medical School

Comparison Of Characteristics Among Korean American Male Smokers Between Survey And Cessation Studies, Sun S. Kim, Seongho Kim, Colleen E. Mckay, Douglas M. Ziedonis

Douglas M. Ziedonis

This study compared characteristics of Korean American men in two studies: a telephone survey with a random sample of Korean American men who reported daily smoking versus a smoking cessation clinical trial with a convenience sample of Korean American men who reported smoking at least 10 cigarettes a day. Guided by the Theory of Planned Behavior (TPB), both studies attempted to explain how much its theoretical variables (attitudes, perceived social norms, and self-efficacy) would explain quit intentions in Korean American men. Participants in the cessation study were less likely to have health insurance coverage (χ2 [2, 271] = 138.31, p ...


Comparison Of Characteristics Among Korean American Male Smokers Between Survey And Cessation Studies, Sun S. Kim, Seongho Kim, Colleen E. McKay, Douglas M. Ziedonis 2017 University of Massachusetts Medical School

Comparison Of Characteristics Among Korean American Male Smokers Between Survey And Cessation Studies, Sun S. Kim, Seongho Kim, Colleen E. Mckay, Douglas M. Ziedonis

Colleen E. McKay

This study compared characteristics of Korean American men in two studies: a telephone survey with a random sample of Korean American men who reported daily smoking versus a smoking cessation clinical trial with a convenience sample of Korean American men who reported smoking at least 10 cigarettes a day. Guided by the Theory of Planned Behavior (TPB), both studies attempted to explain how much its theoretical variables (attitudes, perceived social norms, and self-efficacy) would explain quit intentions in Korean American men. Participants in the cessation study were less likely to have health insurance coverage (χ2 [2, 271] = 138.31, p ...


Computer Administered Safety Planning For Individuals At Risk For Suicide: Development And Usability Testing, Edwin D. Boudreaux, Gregory K. Brown, Barbara Stanley, Rajani S. Sadasivam, Carlos A. Camargo Jr, Ivan W. Miller 2017 University of Massachusetts Medical School

Computer Administered Safety Planning For Individuals At Risk For Suicide: Development And Usability Testing, Edwin D. Boudreaux, Gregory K. Brown, Barbara Stanley, Rajani S. Sadasivam, Carlos A. Camargo Jr, Ivan W. Miller

Rajani S. Sadasivam

BACKGROUND: Safety planning is a brief intervention that has become an accepted practice in many clinical settings to help prevent suicide. Even though it is quick compared to other approaches, it frequently requires 20 min or more to complete, which can impede adoption. A self-administered, Web-based safety planning application could potentially reduce clinician time, help promote standardization and quality, and provide enhanced ability to share the created plan. OBJECTIVE: The aim of this study was to design, build, and test the usability of a Web-based, self-administered safety planning application. METHODS: We employed a user-centered software design strategy led by a ...


Computer Administered Safety Planning For Individuals At Risk For Suicide: Development And Usability Testing, Edwin D. Boudreaux, Gregory K. Brown, Barbara Stanley, Rajani S. Sadasivam, Carlos A. Camargo Jr, Ivan W. Miller 2017 University of Massachusetts Medical School

Computer Administered Safety Planning For Individuals At Risk For Suicide: Development And Usability Testing, Edwin D. Boudreaux, Gregory K. Brown, Barbara Stanley, Rajani S. Sadasivam, Carlos A. Camargo Jr, Ivan W. Miller

Edwin D. Boudreaux

BACKGROUND: Safety planning is a brief intervention that has become an accepted practice in many clinical settings to help prevent suicide. Even though it is quick compared to other approaches, it frequently requires 20 min or more to complete, which can impede adoption. A self-administered, Web-based safety planning application could potentially reduce clinician time, help promote standardization and quality, and provide enhanced ability to share the created plan. OBJECTIVE: The aim of this study was to design, build, and test the usability of a Web-based, self-administered safety planning application. METHODS: We employed a user-centered software design strategy led by a ...


Anxiety Associated Increased Cpg Methylation In The Promoter Of Asb1: A Translational Approach Evidenced By Epidemiological And Clinical Studies And A Murine Model, Rebecca T. Emeny, Jens Baumert, Anthony S. Zannas, Sonja Kunze, Simone Wahl, Stella Iurato 2017 Dartmouth College

Anxiety Associated Increased Cpg Methylation In The Promoter Of Asb1: A Translational Approach Evidenced By Epidemiological And Clinical Studies And A Murine Model, Rebecca T. Emeny, Jens Baumert, Anthony S. Zannas, Sonja Kunze, Simone Wahl, Stella Iurato

Open Dartmouth: Faculty Open Access Articles

Epigenetic regulation in anxiety is suggested, but evidence from large studies is needed. We conducted an epigenome-wide association study (EWAS) on anxiety in a population-based cohort and validated our finding in a clinical cohort as well as a murine model. In the KORA cohort, participants (n= 1522, age 32–72 years) were administered the Generalized Anxiety Disorder (GAD-7) instrument, whole blood DNA methylation was measured (Illumina 450K BeadChip), and circulating levels of hs-CRP and IL-18 were assessed in the association between anxiety and methylation. DNA methylation was measured using the same instrument in a study of patients with anxiety disorders ...


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