Osteopathic Medicine and Osteopathy Commons^™

Osteopathic Manipulative Medicine May Help Hospitalized Patients With Substance Use Disorder., Alisa Cleary, E. Katherine Nenninger, David Keller, Kinna Thakarar

Costas T. Lambrew Research Retreat 2020

OBJECTIVES: Inpatient hospitalization can often offer an opportunity to initiate treatment and preventive care that otherwise would be lost. At our hospital, which is a tertiary care teaching hospital in a region where injection drug use is rising, a multidisciplinary “IMAT” (integrated medication assisted treatment) team is available to facilitate substance use disorder treatment and services. In addition, consultation services for osteopathic manipulative medicine (OMM) are available. Osteopathic manipulative treatment (OMT) can play an important role in the overall healing and well-being of an individual. This non-invasive, hands on approach can improve patient comfort, promote recovery, and potentially reduce length ...

The Implementation Of Exercise For Chronic Kidney Disease And Dialysis Patients, Syed Ahmad Rizvi

Honors College Theses

While commonly known to be the organ that helps with urine production within the human body, the kidney plays one of the most crucial roles in maintaining homeostasis. When establishing all of the roles the kidney has on keeping humans healthy, there is the question of how does the body cope when a patient is diagnosed with kidney failure. One of the more common treatment options that allows the body to continue to function without a kidney is by beginning a patient on a form of dialysis. However, as with any treatment, there will always be a list of side ...

Extra Medullar Granulocytic Sarcoma: A Case Report Of An Exceptional Localization, Bouhani Malek, Sakhri Saida, Jaidane Olfa, Adouni Olfa, Chargui Riadh, Rahal Khaled

Journal of Mind and Medical Sciences

Granulocytic sarcoma is a rare type of tumor composed of extramedullary immature cells. The breast location is very rare; it accounts for less than 8% of cases. The present study reports the case of a 36-year-old female with a medical history of myelodysplastic syndrome. She was referred because of a lump in the left breast. We have diagnosed a case of granulocytic sarcoma of the breast by core biopsy. Histology and immunohistochemistry showed hypercellular smears with immature myeloid cells. The blast cells were myeloperoxidase positive.

The patient underwent a lumpectomy. Five months later, she developed a contralateral recurrence, treated by ...

Bmd-Related Genetic Risk Scores Predict Site-Specific Fractures As Well As Trabecular And Cortical Bone Microstructure, Maria Nethander, Ulrika Pettersson-Kymmer, Liesbeth Vandenput, Mattias Lorentzon, Magnus Karlsson, Dan Mellström, Claes Ohlsson

Faculty of Health Sciences Publications

Context: It is important to identify patients at highest risk of fractures. Objective: To compare the separate and combined performances of bone-related genetic risk scores (GRSs) for prediction of forearm, hip and vertebral fractures separately, as well as of trabecular and cortical bone microstructure parameters separately. Design, Setting, and Participants: Using 1103 single nucleotide polymorphisms (SNPs) independently associated with estimated bone mineral density of the heel (eBMD), we developed a weighted GRS for eBMD and determined its contribution to fracture prediction beyond 2 previously developed GRSs for femur neck BMD (49 SNPs) and lumbar spine BMD (48 SNPs). Associations between ...

Epidemiology Of Hip Fractures In Bulgaria: Development Of A Country-Specific Frax Model, E. Kirilova, H. Johansson, N. Kirilov, S. Vladeva, T. Petranova, Z. Kolarov, E. Liu, M. Lorentzon, L. Vandenput, N. C. Harvey, E. Mccloskey, John A. Kanis

Faculty of Health Sciences Publications

Summary: A retrospective population-based survey was undertaken in a region of Bulgaria to determine the incidence of hip fracture. The estimated number of hip fractures nationwide for 2015 was 9322 and is predicted to increase to 11,398 in 2050. The hip fracture rates were used to create a FRAX model. Objective: To describe the epidemiology of hip fractures in Bulgaria, which was then used to develop the country-specific fracture prediction FRAX® tool. Methods: We carried out a retrospective population-based survey in Stara Zagora, Bulgaria, representing approximately 4.6% of the country’s population. We identified hip fractures occurring in ...

Prevention And Treatment Of Glucocorticoid-Induced Osteoporosis, Mackenzie Devine, Anh Dao Le, Julie Puvogel, Victoria Cho, Michelle Musser

Pharmacy and Wellness Review

Osteoporosis is a disease state resulting in decreased bone mineral density (BMD) and increased risk of fracture, specifically of the vertebrae, spine and hip. Risk factors and high risk populations for developing osteoporosis include low BMD, long-term glucocorticoid therapy, genetics, diet, postmenopausal women and patients with inflammatory or chronic disease states. A variety of signaling pathways involving hormones, cytokines and other signaling molecules are involved in bone formation and are affected by long-term glucocorticoid therapy, leading to the development of glucocorticoid-induced osteoporosis (GIO).

There are a variety of drugs that work efficaciously to prevent and treat GIO. Alendronate is a ...

Osteoarthritis: Natural Supplements For Joint Health, Katherine Salay, Kimberly Gathers, Lindsey Mcclish, Lisa Vranekovic, Kristen Seaman, Ryan W. Naseman

Pharmacy and Wellness Review

An estimated 46 million adults in the U.S. are affected by arthritis, with osteoarthritis (OA) being the most common. Due to the limited pharmacologic therapy available to treat this condition, many patients are turning to dietary supplements to relieve their symptoms. Some of the most popular supplements available for the treatment of OA are glucosamine, chrondroitin and methylsulfonylmethane (MSM), but many less studied products are also available. Due to limited evidence of efficacy, it is difficult to make a strong recommendation for any of these products; however, pharmacists must be able to educate the patients that choose to use ...

Empathy Learned Through An Extended Medical Education Virtual Reality Project, Wilson Mei, Elizabeth Dyer, Barbara Swartzlander, Marilyn R. Gugliucci

Osteopathic Medicine Student Research Posters

Studies have suggested that empathy in healthcare professionals tends to erode during medical school and residency training. However, a study conducted by Hofat presents outcomes that reveals the opposite effect; instead empathy improves or there is no effect on empathy at all. Despite the contradictory studies, it is generally agreed that empathy is an important aspect in the patient-physician relationship as it is associated with improved patient satisfaction, increased adherence to treatment, and fewer malpractice complaints. This research exposed 346 first year medical students to virtual reality (VR) technology that is intended to elicit empathy for a 74-year-old African American ...

Identification Of A Bone Morphogenetic Protein Type 2 Receptor Neutralizing Antibody, Ruthann Gorrell, Madeline Totten, Laura Schoerning, Jordan B. Newby, Logan J. Geyman, Warren Lawless, Julia M. Hum, Jonathan W. Lowery Ph.D.

Student Publications and Research

The bone morphogenetic protein (BMP) signaling pathway comprises the largest subdivision of the transforming growth factor (TGFβ) superfamily. BMP signaling plays essential roles in both embryonic development and postnatal tissue homeostasis. Dysregulated BMP signaling underlies human pathologies ranging from pulmonary arterial hypertension to heterotopic ossification. Thus, understanding the basic mechanisms and regulation of BMP signaling may yield translational opportunities. Unfortunately, limited tools are available to evaluate this pathway, and genetic approaches are frequently confounded by developmental requirements or ability of pathway components to compensate for one another. Specific inhibitors for type 2 receptors are poorly represented. Thus, we sought to ...

Omt For The Treatment Of Depression And Anxiety, Zachary Winchell

Stratford Campus Research Day

Osteopathic manipulative therapy (OMT) fundamentally aims to remedy somatic dysfunction through the manipulation of the patient. In this regard, OMT is a particularly viable non-pharmacological adjunct for patients with depressive and generalized anxiety disorder (GAD).

In both of these disorders, the hypothalamic-pituitary-adrenal axis has an interdependent relationship with physiological stress that feed one another to both increase symptomology and leave patients vulnerable to negative life events. Additionally, pro-inflammatory cytokines acting on the brain over long periods of time can lead to exacerbation of disease and the development of depression in susceptible individuals. Altered cytokine balance has also been found in ...

The Effect Of Omm On Opioid Users With Chronic Low Back Pain, Danielle Cooley D.O., James Bailey D.O., Deanna Janora M.D., Catherine Fusco D.O., Kishan Patel

Stratford Campus Research Day

In the United States, approximately 100 million adults are affected by chronic pain, which reduces their quality of life and productivity, while accounting for billions in health care costs and lost revenue. (1) Opioids are considered the gold standard in the pharmacological treatment for chronic pain conditions, and prescriptions for opiates/opioids increased by 400% from 1999 to 2010. (1,2) Although opioid treatment is warranted during postsurgical and active cancer pain, physicians still commonly overprescribe opioids, which has led to addiction, high deaths rates by overdose, and the spread of communicable diseases. (1)

Since chronic pain is sustained by ...

Rsv-Encoded Ns2 Promotes Epithelial Cell Shedding And Distal Airway Obstruction, R. M. Liesman, U. J. Buchholz, C. L. Luongo, A. D. Proia, J. P. Divicenzo, P. L. Collins, R. J. Pickles

Osteopathic Medicine, Jerry M. Wallace School of

Respiratory syncytial virus (RSV) infection is the major cause of bronchiolitis in young children. The factors that contribute to the increased propensity of RSV-induced distal airway disease compared with other commonly encountered respiratory viruses remain unclear. Here, we identified the RSV-encoded nonstructural 2 (NS2) protein as a viral genetic determinant for initiating RSV-induced distal airway obstruction. Infection of human cartilaginous airway epithelium (HAE) and a hamster model of disease with recombinant respiratory viruses revealed that NS2 promotes shedding of infected epithelial cells, resulting in two consequences of virus infection. First, epithelial cell shedding accelerated the reduction of virus titers, presumably ...

Physicians’ Knowledge And Beliefs Regarding Athletic Trainers, Joseph H. Vogler, Lindsey E. Eberman, Zachary K. Winkelmann, M. Seth Smith, James L. Turner, Kenneth E. Games

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

Purpose: The relationship between athletic trainers (ATs) and physicians is a legal obligation and collaboration to improve patient outcomes. The objective of this study was to examine the knowledge of physicians regarding the educational preparation, legal obligations, and scope of practice for ATs and how it relates to previous experiences with ATs. Additionally physicians’ perceptions of Interprofessional Collaboration (IPC) were studied. Methods: 169 physicians medical doctors (MD)=133/169, 78.7%, doctor of osteopathy (DO)=36/169, 21%) completed a 36-question web-based survey, which included a validated IPC scale. Results: Respondents with experience working with an AT scored significantly higher ...

Analysing Outcomes Through Orthopaedic Trauma Registry: A Prospective Cohort Study, Tashfeen Ahmad, Zehra Abdul Muhammad, Shahryar Noordin, Ammar Humayun

Section of Orthopaedic Surgery

Objective: To develop a registry for recording injury-specific data to identify gaps and improve care.

Methods: The prospective cohort study was conducted at Aga Khan University Hospital, Karachi, from June 2015 to July 2018 though enrollment of patients with limb trauma is continuing to date. Data on injuries and management related to Tibia shaft fractures was collected from medical records, and outcomes were assessed on follow-up visits. Internationally validated injury-specific scores were utilised for assessing functional, clinical and radiological outcomes. SPSS version 19 was used for data analysis.

Results: There were 763 patients with 825 limb injuries. Of the injuries ...

Dr. Kiran C. Patel College Of Osteopathic Medicine Graduate Programs, Nova Southeastern University

Health Professions Divisions Course Catalogs

No abstract provided.

Nutrition Manual For Nsu Student Athletes, Kaitlyn Flaskerud, Katie Emerson, Stephanie Fonesca, Angel Marquez, Alejandra Velandia, Marilyn Gordon

Faculty Articles

No abstract provided.

Is Craniosacral Therapy Effective In The Reduction Of Pain Intensity In Individuals With Non-Specific Neck And/Or Back Pain?, Melissa A. Stefanosky

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective evidence based medicine review is to determine whether or not craniosacral therapy is effective in the reduction of pain intensity in individuals with non-specific neck and/or back pain.

STUDY DESIGN: A systemic review of three peer reviewed journal articles published in 2014 and 2016.

DATA SOURCES: Three randomized controlled trials comparing craniosacral therapy to sham treatment, classic massage and/or trigger point therapy. These data sources were found using PubMed.

OUTCOMES MEASURED: Pain intensity in the neck and/or back, measured by using a 10- point numeric pain rating scale and the visual ...

Synapsis: Philadelphia Campus (2019), Philadelphia College Of Osteopathic Medicine

All Yearbooks

The 2019 Philadelphia Campus Synapsis includes Orientation, White Coat, Gala, Life at PCOM, Anatomy Groups, Radiology, Family Medicine, Match.

Pathological Mechanisms And Therapeutic Outlooks For Arthrofibrosis, Kayley M. Usher, Sipin Zhu, Georgios Mavropalias, John A. Carrino, Jinmin Zhao, Jiake Xu

ECU Publications Post 2013

Arthrofibrosis is a fibrotic joint disorder that begins with an inflammatory reaction to insults such as injury, surgery and infection. Excessive extracellular matrix and adhesions contract pouches, bursae and tendons, cause pain and prevent a normal range of joint motion, with devastating consequences for patient quality of life. Arthrofibrosis affects people of all ages, with published rates varying. The risk factors and best management strategies are largely unknown due to a poor understanding of the pathology and lack of diagnostic biomarkers. However, current research into the pathogenesis of fibrosis in organs now informs the understanding of arthrofibrosis. The process begins ...

A Novel Multiscale Mathematical Model For Building Bone Substitute Materials For Children, Abdennasser Chekroun, Laurent Pujo-Menjouet, Jean-Philippe Berteau

Publications and Research

Bone is an engineering marvel that achieves a unique combination of stiffness and toughness exceeding that of synthesized materials. In orthopedics, we are currently challenged for the child population that needs a less stiff but a tougher bone substitute than adults. Recent evidence suggests that the relationship between inter-molecular connections that involve the two main bone building blocks, TropoCollagen molecules (TC) and carbonated Hydroxyapatite (cAp), and bone macroscopic mechanical properties, stiffness and toughness, are key to building bone substitute materials for children. The goal of our study is to establish how inter-molecular connections that occur during bone mineralization are related ...