Evidence For Minimal Cardiogenic Potential Of Stem Cell Antigen 1-Positive Cells In The Adult Mouse Heart., 2018 Cardiology Division, Swedish Medical Center, Seattle, WA.
Evidence For Minimal Cardiogenic Potential Of Stem Cell Antigen 1-Positive Cells In The Adult Mouse Heart., Lauren E Neidig, Florian Weinberger, Nathan J Palpant, John Mignone, Amy M Martinson, Daniel W Sorensen, Ingrid Bender, Natsumi Nemoto, Hans Reinecke, Lil Pabon, Jeffery D Molkentin, Charles E Murry, Jop H Van Berlo
Journal Articles and Abstracts
No abstract provided.
Keep The Beat With Heart Failure Education: A Quality Improvement Project, 2018 University of San Francisco
Keep The Beat With Heart Failure Education: A Quality Improvement Project, Brenda L. Peterson
Master's Projects and Capstones
Problem: Heart failure (HF), also known as congestive heart failure (CHF), is the number one diagnosis-related group (DRG) for people 65 years of age and older in the United States. This disease group is complicated and debilitating, requiring frequent hospitalizations with high mortality rates. The Joint Commission on Accreditation of Healthcare Organizations (JCAHO) has identified CHF as an area for improvement in hospitals.
Context: This was a quality improvement project for an integrated medical center in the Central Valley, California with over 19,000 HF patients. In 2018, for patients 65 years and older, HF is the third-most admitted ...
Are Patients Living With Hiv Infection At Risk For Not Receiving Statin Medications For Cardiovascular Disease Risk Reduction?, 2018 Thomas Jefferson University
Are Patients Living With Hiv Infection At Risk For Not Receiving Statin Medications For Cardiovascular Disease Risk Reduction?, Nick Hastain, Pharmd Candidate, Roshni S. Patel, Pharmd, Bcps, Jason J. Schafer, Pharmd, Mph, Bcps, Aahivp
College of Pharmacy Posters
To determine the prevalence of appropriate statin prescribing for ASCVD risk reduction in PLWH
Perioperative Aspirin And Long-Term Survival In Patients Undergoing Coronary Artery Bypass Graft., 2018 Thomas Jefferson University; The Fourth Military Medical University
Perioperative Aspirin And Long-Term Survival In Patients Undergoing Coronary Artery Bypass Graft., Qian Ding, Hong Liu, Zugui Zhang, Jordan E. Goldhammer, Eric Yuen, Zhongmin Li, Linong Yao, Nilas Young, Douglas Boyd, William Weintraub, Rohinton Morris, Jianzhong Sun
Department of Anesthesiology Faculty Papers
This study aimed to examine association between perioperative uses of aspirin and long-term survival in patients undergoing CABG. A retrospective cohort study was performed in 9,584 consecutive patients receiving cardiac surgery from three tertiary hospitals. Of all the patients, 4,132 patients undergoing CABG met inclusion criteria and were divided into four groups: with or without preoperative or postoperative aspirin respectively. 30-day postoperative and long-term mortality were compared with the use of propensity scores and inverse probability weighting adjustment to reduce the treatment-selection bias. The patients taking preoperative aspirin presented significantly more with comorbidities. However, the results of this ...
Magnitude And Impact Of Multiple Chronic Conditions With Advancing Age In Older Adults Hospitalized With Acute Myocardial Infarction, 2018 University of Massachusetts Medical School
Magnitude And Impact Of Multiple Chronic Conditions With Advancing Age In Older Adults Hospitalized With Acute Myocardial Infarction, Mayra Tisminetzky, Hoa L. Nguyen, Jerry H. Gurwitz, David D. Mcmanus, Joel M. Gore, Sonal Singh, Jorge L. Yarzebski, Robert J. Goldberg
Open Access Articles
BACKGROUND: To examine age-specific differences in the frequency and impact of cardiac and non-cardiac conditions among patients aged 65years and older hospitalized with acute myocardial infarction (AMI).
METHODS: Study population consisted of 3863 adults hospitalized with AMI at 11 medical centers in central Massachusetts on a biennial basis between 2001 and 2011. The presence of 11 chronic conditions (five cardiac and six non-cardiac) was based on the review of hospital medical records.
RESULTS: Participants' median age was 79years, 49% were men, and had an average of three chronic conditions (average of cardiac conditions: 2.6 and average of non-cardiac conditions ...
Restoration Of Left Ventricular Function Following Lvad Implantation – Remission Or Recovery? A Case Series., 2018 University of Kentucky
Restoration Of Left Ventricular Function Following Lvad Implantation – Remission Or Recovery? A Case Series., Shiksha Joshi, Mariah Barlow, Maya Guglin
The VAD Journal
A wide range of left ventricular (LV) recovery rates on left ventricular assist device (LVAD) support have been reported. In this case series, we summarize our experience with LVAD explantation for presumed LV recovery.
Out of 240 patients who received an LVAD implant in our program since its inception, we explanted/inactivated the pump for presumed LV recovery in only three patients. All three of these patients had relapse of cardiomyopathy within 6 months of explantation.
Our experience does not support the existence of LV recovery following LVAD implantation as a common phenomenon. Improvement in LV ...
Designing Tailored Patient Education On Atrial Fibrillation, 2018 Parkview Health
Designing Tailored Patient Education On Atrial Fibrillation, Tammy Toscos, R Ahmed, Romisa Rohani Ghahari, Elizabeth Martin, Shauna Wagner, Michelle Drouin, Michael J. Mirro
Presentations and Events
Background & Hypothesis: Research has revealed a high prevalence of depression, anxiety, and burnout among medical students accompanied by widespread lack of treatment. We hypothesize that by leveraging our study findings examining the use of telemental health(TMH) among youth (ages 14-24) alongside results from existing research focused on the mental health needs of medical students (median age at start 22-24 years old), we will gain valuable insight into the potential for TMH to address the needs of this high-risk population.
Methods: Using the Delphi method, a sample of 25 experts were surveyed anonymously, thus avoiding group pressure for conformity while ...
Examining Symptom Trajectories That Predict Worse Outcomes In Post-Cabg Patients, 2018 Chang Gung University of Science and Technology, Taiwan
Examining Symptom Trajectories That Predict Worse Outcomes In Post-Cabg Patients, Ming-Fen Tsai, Shiow-Luan Tsay, Debra K. Moser, Tsuey-Yuan Huang, Feng-Chun Tsai
Nursing Faculty Publications
Background: Coronary artery bypass grafting is one of the most common interventional revascularisation procedures used to treat coronary artery disease worldwide. With a wide variability in postoperative cardiac symptoms, identification of symptom trajectories during the 3-month postoperative recovery period may improve clinicians’ abilities to support symptom recovery.
Aims: To identify distinct trajectories of cardiac symptoms seen over time in a cohort of patients during the 3-month post-coronary artery bypass grafting period, and determine clinical characteristics associated with different symptom trajectories postoperatively.
Methods: A prospective trial used the cardiac symptom survey to determine patient symptoms at baseline prior to surgery, and ...
Outcomes Of Transcutaneous Aortic Valve Replacement Among High Risk Wv Sample Population., 2018 Marshall University
Outcomes Of Transcutaneous Aortic Valve Replacement Among High Risk Wv Sample Population., George M. Yousef, Julia Poe, Cameron Killmer, Basel Edris, Jason Mader, Ellen A. Thompson, Daniel Snavely, Silvestre Cansino, Joseph I. Shapiro, Mark A. Studeny
Marshall Journal of Medicine
Introduction:Transcatheter aortic valve replacement (TAVR) is a relatively new strategy for replacing the aortic valve. We elected to review our early experience to see if we could identify clinical characteristics at baseline or immediately following the procedure that would predict death within one year.
Methods:Charts for all patients assigned to receive TAVR procedure at St Mary’s medical center, Huntington, West Virginia between April, 2013 till November, 2016 were identified and reviewed. A total of seventy-two (72) cases were included.
Results: All cause mortality rate at index hospitalization, 30 days, and 12 months was 5.6%(N=4 ...
Conference Proceedings: Aurora Scientific Day 2018, 2018 Aurora Health Care
Conference Proceedings: Aurora Scientific Day 2018
Journal of Patient-Centered Research and Reviews
This journal supplement includes selected abstracts from among the more than 50 presented at the 44th annual Aurora Scientific Day research symposium. Held May 25, 2018, in Milwaukee, Wisconsin, Aurora Scientific Day provides a forum for original research conducted by faculty, fellows, residents, and other allied health professionals affiliated with Aurora Health Care, an integrated health system with hospitals and clinics in Wisconsin and Illinois.
Problems Experienced In The Second And Third Months After Discharge From A Heart Failure-Related Hospitalization, 2018 University of Alabama at Birmingham School of Nursing
Problems Experienced In The Second And Third Months After Discharge From A Heart Failure-Related Hospitalization, Joan S. Grant, Lucinda J. Graven
Journal of Patient-Centered Research and Reviews
The purpose of this study was to identify high-priority problems experienced by individuals during the second and third month after discharge from an acute care facility for heart failure. This descriptive, exploratory study, an extension of a previous analysis that examined high-priority problems in the first month, comprised 19 participants who were assigned to an intervention group that received a randomized, 12-week-pilot coping partnership (COPE-HF) intervention. A trained research nurse provided the intervention, and participants used a standard list to identify high-priority heart failure-related problems. Quantitative and content data analysis was conducted. While the highest-priority problem continued to be managing ...
Hyperglycemia And Risk Of Ventricular Tachycardia Among Patients Hospitalized With Acute Myocardial Infarction, 2018 University of Massachusetts Medical School
Hyperglycemia And Risk Of Ventricular Tachycardia Among Patients Hospitalized With Acute Myocardial Infarction, Hoang V. Tran, Joel M. Gore, Chad E. Darling, Arlene S. Ash, Catarina I. Kiefe, Robert J. Goldberg
Open Access Articles
BACKGROUND: Little is known about the association of hyperglycemia Tranwith the development of ventricular tachycardia (VT) in patients hospitalized with acute myocardial infarction (AMI) which we examined in the present study. The objectives of this community-wide observational study were to examine the relation between elevated serum glucose levels at the time of hospital admission for AMI and occurrence of VT, and time of occurrence of VT, during the patient's acute hospitalization.
METHODS: We used data from a population-based study of patients hospitalized with AMI at all central Massachusetts medical centers between 2001 and 2011. Hyperglycemia was defined as a ...
New Oral Anticoagulants And Their Reversal Agents, 2018 Clinical Emergency Hospital of Bucharest, Internal Medicine Clinic, Bucharest, Romania
New Oral Anticoagulants And Their Reversal Agents, Crista L. Laslo, Anca Pantea Stoian, Bogdan Socea, Dan N. Paduraru, Oana Bodean, Laura I. Socea, Tiberiu P. Neagu, Ana Maria Alexandra Stanescu, Dragos Marcu, Camelia C. Diaconu
Journal of Mind and Medical Sciences
Atrial fibrillation is a commonly encountered pathology in medical practice, and its prevalence has shown a continuous rise over the past years. Atrial fibrillation has a significant impact on patients' quality of life, not only due to the standard anticoagulant treatment with vitamin K antagonists that require close monitoring and dose adjustment, but also due to the fragile equilibrium between hemorrhagic and thrombotic risks. The introduction of new oral anticoagulants (NOACs) in the treatment guidelines for atrial fibrillation has improved the quality of life, as NOACs do not require close monitoring or dose adjustments. However, even if the safety profile ...
Strategies To Increase Early Discharges To Reduce Avoidable Patient Days And Improve Patient Flow, 2018 Maine Medical Center
Strategies To Increase Early Discharges To Reduce Avoidable Patient Days And Improve Patient Flow, Cathy Palleschi, Cecilia Inman, Erica Weightman, James B. Powers, Stephen Tyzik, Joy Moody, Mark Parker, Suneela Nayak, Ruth Hanselman, Amy Sparks
CREATING ALGORITHMS TO INCREASE THE NUMBERS OF HOSPITAL MORNING DISCHARGES RESULTING IN IMPROVED PATIENT FLOW
Discharging a percentage of patients early in the day helps to improve patient flow. This results in a reduction of Emergency Department congestion as well as peaks in patient numbers in the early to late afternoon on patient care units.
A cardiac unit in an academic tertiary medical center created a goal to increase the number of their discharges by 11 AM and to streamline key discharge planning activities. A root cause analysis was initiated and after identifying several barriers, two KPIs were developed using ...
Association Of Arginine Vasopressin With Low Atrial Natriuretic Peptide Levels, Left Ventricular Remodelling, And Outcomes In Adults With And Without Heart Failure, Julio A. Chirinos, Mayank Sardana, Garrett Oldland, Bilal Ansari, Jonathan Lee, Anila Hussain, Anique Mustafa, Scott R. Akers, Wen Wei, Edward G. Lakatta, Olga V. Fedorova
Open Access Articles
AIMS: The arginine vasopressin (AVP) pathway has been extensively studied in heart failure (HF) with reduced ejection fraction (HFrEF), but less is known about AVP in HF with preserved EF (HFpEF). Furthermore, the association between AVP and atrial natriuretic peptide (ANP, a well-known inhibitor of AVP secretion) in HF is unknown.
METHODS AND RESULTS: We studied subjects with HFpEF (n = 28) and HFrEF (n = 25) and without HF (n = 71). Left ventricular (LV) mass and left atrial (LA) volumes were measured with cardiac magnetic resonance imaging. Arginine vasopressin and ANP were measured with enzyme-linked immunosorbent assay. Arginine vasopressin levels were ...
Outcome Of Radioactive Iodine Therapy In Toxic Nodular Goiter In Pakistan, 2018 Aga Khan University
Outcome Of Radioactive Iodine Therapy In Toxic Nodular Goiter In Pakistan, Tauseef Ahmad, Adeel Khoja, Naveed Rashid, Muhammad Areeb Ashfaq
Section of Cardiology
Objective: To determine the outcome of patients receiving radioactive iodine therapy for toxic nodular goiter coming to Aga Khan University Hospital Karachi.
Methods: A total of 89 patients who visited the outpatient department of Aga Khan University Hospital from January 2010 to August 2017 were recruited for the study. Toxic nodular goiter was diagnosed on the basis of having hot nodule on thyroid scan with low TSH and high FT4/T4. Other demographic and laboratory data were also recorded.
Results: Eighty nine patients with toxic nodular goiter received a dose range from 10 to 30mCi RAI. Six months after RAI ...
Effects Of Beta Blockers And Ace Inhibitors After Left Ventricular Assist Device Implantation, 2018 University of Louisville
Effects Of Beta Blockers And Ace Inhibitors After Left Ventricular Assist Device Implantation, Gaurang Vaidya, Emma Birks, Jessica Pillarella, Benjamin Salgado, Rajakrishnan Vijayakrishnan, Andrew Lenneman, Mark Slaughter, Dmitry Abramov
The VAD Journal
Purpose: While Beta blockers(BB) and Angiotensin system blockers(ACEinh/ARB) are important components in advanced heart failure therapy, their use after left ventricular assist device (LVAD) implantation remains controversial. Concern has been raised about possible adverse effects of BB on right ventricular(RV) function while tolerance and efficacy/outcome data for ACEinh are lacking. This study aimed to characterize the use of medical therapy post-LVAD implantation and to evaluate its safety and efficacy. Methods: Demographic, clinical and echocardiographic variables of patients implanted with a continuous-flow LVAD between 2012 and 2015 at a single center were retrospectively reviewed. Mortality and ...
Support-Af: Piloting A Multi-Faceted, Electronic Medical Record-Based Intervention To Improve Prescription Of Anticoagulation, 2018 Boston University School of Medicine
Support-Af: Piloting A Multi-Faceted, Electronic Medical Record-Based Intervention To Improve Prescription Of Anticoagulation, Alok Kapoor, Azraa Amroze, Jessica G. Golden, Sybil L. Crawford, Kevin O'Day, Rasha Elhag, Ahmed Nagy, Steve A. Lubitz, Jane S. Saczynski, Jomol Mathew, David D. Mcmanus
Open Access Articles
Background: Only 50% of eligible atrial fibrillation ( AF ) patients receive anticoagulation ( AC ). Feasibility and effectiveness of electronic medical record (EMR)-based interventions to profile and raise provider AC percentage is poorly understood. The SUPPORT-AF (Supporting Use of AC Through Provider Profiling of Oral AC Therapy for AF) study aims to improve rates of adherence to AC guidelines by developing and delivering supportive tools based on the EMR to providers treating patients with AF.
Methods and Results: We emailed cardiologists and community-based primary care providers affiliated with our institution reports of their AC percentage relative to peers. We also sent an ...
A Patient-Centered Approach Towards Designing A Novel Cied Remote Monitoring Report, 2018 Parkview Health
A Patient-Centered Approach Towards Designing A Novel Cied Remote Monitoring Report, Michael J. Mirro, Romisa Rohani Ghahari, R Ahmed, Lauren Reining, Shauna Wagner, Gavin Lehmann, Jaime Heller, Melissa Omlor, Tammy Toscos
Presentations and Events
Objective: We sought to identify the CIED remote monitoring device report content for delivery to patients via a Personal Health Record that encompasses all available device data and is responsive to user information needs and preferences.
Conclusions: 1. Patients do not wish to receive all RM data 2. Interested in receiving device activity and cardiac episode data 3. Not interested in device settings or information 4. Shared preferences are useful for a novel patient-centered RM report 5. Current study extends our previous work confirming the patient desire for RM data
Antiphosphatidylserine Antibody As A Cause Of Multiple Dural Venous Sinus Thromboses And St-Elevation Myocardial Infarction, 2018 Thomas Jefferson University
Antiphosphatidylserine Antibody As A Cause Of Multiple Dural Venous Sinus Thromboses And St-Elevation Myocardial Infarction, Chelsea K. Varner, Caillin W. Marquardt, Peter V. Pickens
Student Papers & Posters
Objective: Rare disease Background: Antiphospholipid syndrome (APS) is an autoimmune disease characterized by antibodies directed against phos-pholipids on plasma membranes. Through unclear mechanisms, APS confers hypercoagulability. APS may cause recurrent thromboses in the arterial and venous vasculature. We report a case of primary APS resulting in cerebral venous thrombosis and ST-elevation myocardial infarction (STEMI) for which only antiphosphatidylserine (aPS) IgM antibody was positive after extensive investigation. Case Report: A 48-year-old male was admitted after a witnessed generalized seizure with subsequent confusion. Imaging demonstrated thrombosis of multiple central nervous system (CNS) sinuses, including the superior sagittal sinus and bilateral transverse sinuses ...