13 Institutions 34 Full-Text Articles 118 Authors 2,570 Downloads
Recent Articles in Allergy and Immunology
What Treatments Are Effective For Nickel Allergy?, Joseph Lesnick, José E. Rodríguez MD The Florida State University
What Treatments Are Effective For Nickel Allergy?, Joseph Lesnick, José E. Rodríguez Md
Family Medicine and Rural Health Faculty Publications
Preventing further exposure is clearly important. Postexposure, topical tacrolimus and topical steroids improve symptoms of nickel allergy better than placebo (SOR: B, 2 small RCTs).
Targeted Sirna Delivery Methods For Rnai-Based Therapies, Di Chen Western University
Targeted Sirna Delivery Methods For Rnai-Based Therapies, Di Chen
University of Western Ontario - Electronic Thesis and Dissertation Repository
RNAi has great potential in future therapeutics as it has the ability to regulating many disease-related genes. However, many barriers prevent practical applications. To overcome the barriers, the specific targeting, efficient delivery system, the validated gene and the potent siRNA sequence are all vital important. The studies throughout this thesis have been focued on examining the validation of three RNAi therapies for two different disease models: allergic contact dermatitis and melanoma. For allergic contact dermatitis, I developed and tested a novel topical delivery system for siRNAs targeting TNFα (siTNFα) and MyD88 siRNA (siMyD88). While siRNAs applied without the transdermal enhancer ...
Adaptive Events In The Tumor Limit The Success Of Cancer Immunotherapy, AJ Robert McGray McMaster University
Adaptive Events In The Tumor Limit The Success Of Cancer Immunotherapy, Aj Robert Mcgray
Open Access Dissertations and Theses
Pre-clinical and clinical data strongly support the use of immunotherapies for cancer treatment. Cancer vaccines offer a promising approach, however, the outcomes of clinical vaccine trials have been largely disappointing, prompting a need for further investigation. Using the B16F10 murine melanoma, we have investigated the local events within growing tumors following recombinant adenovirus immunization. In chapter 2, we investigated the ability of a pre-clinical vaccine to elicit only transient tumor growth suppression. We observed that tumors were initially infiltrated by a small number of highly functional tumor-specific CD8+ T cells following vaccination that instigated a rapid adaptive response in the ...
A Case Of A Male With Fever And Fatigue, Steve Ting Thomas Jefferson University
A Case Of A Male With Fever And Fatigue, Steve Ting
The Medicine Forum
This is a case of a 78 year old Caucasian gentleman who presented to the hospital in the early summer with complaints of high fevers and progressive fatigue. The patient lives near Philadelphia and enjoys doing yard work. He reported finding a tick attached to the skin near his groin approximately 3 weeks prior to admission. The tick was removed; however the patient was unsure of the duration of the tick attachment. He also denied developing any significant rash in that area. He had no recent sick contacts and no recent history of travel. He began developing fever spikes up ...
Human Papillomavirus Among Gay And Bisexual Men: The Need For Education And Vaccination 2012, Anne Fernandez, Elsa Larson University of Rhode Island
Human Papillomavirus Among Gay And Bisexual Men: The Need For Education And Vaccination 2012, Anne Fernandez, Elsa Larson
Lesbian Gay Bisexual Transgender Queer Center
In the United States, rates of anal cancer among MSM are higher than rates of cervical cancer among women. This presentation has a Ms Power point and PDF.
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Phase 2 Clinical Trial Of A Recombinant Adeno-Associated Viral Vector Expressing Α1-Antitrypsin: Interim Results, Christian Mueller, Terence Flotte, Margaret Humphries, Louis Messina
Induction Of Group Ivc Phospholipase A2 In Allergic Asthma: Transcriptional Regulation By Tnf-Α In Bronchoepithelial Cells, Christian Mueller, Terence Flotte
Long-Term Correction Of Very Long-Chain Acyl-Coa Dehydrogenase Deficiency In Mice Using Aav9 Gene Therapy, Christian Mueller, Qiushi Tang, Terence Flotte, Allison Keeler, Scott Shaffer
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