Open Access. Powered by Scholars. Published by Universities.®

Gastroenterology Commons

Open Access. Powered by Scholars. Published by Universities.®

675 Full-Text Articles 1604 Authors 76652 Downloads 44 Institutions

All Articles in Gastroenterology

Faceted Search

675 full-text articles. Page 1 of 27.

Multicenter, Randomized Study To Optimize Bowel For Colon Capsule Endoscopy, David Kastenberg, Wilmot C. Burch Jr, David P. Romeo, Pankaj K. Kashyap, David C. Pound, Neophytos Papageorgiou, Ignacio Fernández-Urien Sainz, Carly E. Sokach, Douglas K. Rex 2017 Thomas Jefferson University

Multicenter, Randomized Study To Optimize Bowel For Colon Capsule Endoscopy, David Kastenberg, Wilmot C. Burch Jr, David P. Romeo, Pankaj K. Kashyap, David C. Pound, Neophytos Papageorgiou, Ignacio Fernández-Urien Sainz, Carly E. Sokach, Douglas K. Rex

Division of Gastroenterology and Hepatology Faculty Papers

AIM To assess the cleansing efficacy and safety of a new Colon capsule endoscopy (CCE) bowel preparation regimen. METHODS This was a multicenter, prospective, randomized, controlled study comparing two CCE regimens. Subjects were asymptomatic and average risk for colorectal cancer. The second generation CCE system (PillCam® COLON 2; Medtronic, Yoqneam, Israel) was utilized. Preparation regimens differed in the 1st and 2nd boosts with the Study regimen using oral sulfate solution (89 mL) with diatrizoate meglumine and diatrizoate sodium solution (“diatrizoate solution”) (boost 1 = 60 mL, boost 2 = 30 mL) and the Control regimen oral sulfate solution (89 mL ...


Risk Of Post-Ercp Pancreatitis In Liver Transplant Patients: Single Center Experience, Shailender Singh 2017 Selected Works

Risk Of Post-Ercp Pancreatitis In Liver Transplant Patients: Single Center Experience, Shailender Singh

Shailender Singh

No abstract provided.


Site-Specific Selection Reveals Selective Constraints And Functionality Of Tumor Somatic Mtdna Mutations., Deyang Li, Xiaohong Du, Xu Guo, Lei Zhan, Xin Li, Chun Yin, Cheng Chen, Mingkun Li, Bingshan Li, Hushan Yang, Jinliang Xing 2017 Fourth Military Medical University

Site-Specific Selection Reveals Selective Constraints And Functionality Of Tumor Somatic Mtdna Mutations., Deyang Li, Xiaohong Du, Xu Guo, Lei Zhan, Xin Li, Chun Yin, Cheng Chen, Mingkun Li, Bingshan Li, Hushan Yang, Jinliang Xing

Department of Medical Oncology Faculty Papers

BACKGROUND: Previous studies have indicated that tumor mitochondrial DNA (mtDNA) mutations are primarily shaped by relaxed negative selection, which is contradictory to the critical roles of mtDNA mutations in tumorigenesis. Therefore, we hypothesized that site-specific selection may influence tumor mtDNA mutations.

METHODS: To test our hypothesis, we developed the largest collection of tumor mtDNA mutations to date and evaluated how natural selection shaped mtDNA mutation patterns.

RESULTS: Our data demonstrated that both positive and negative selections acted on specific positions or functional units of tumor mtDNAs, although the landscape of these mutations was consistent with the relaxation of negative selection ...


Conference Proceedings: Aurora Scientific Day 2017, 2017 Aurora Health Care

Conference Proceedings: Aurora Scientific Day 2017

Journal of Patient-Centered Research and Reviews

This supplement includes select abstracts presented at the 43rd Annual Aurora Scientific Day research symposium on May 24, 2017. Aurora Scientific Day hosts a forum for original research conducted by faculty, fellows, residents, and other allied health professionals affiliated with Aurora Health Care, an integrated health system headquartered in Milwaukee, Wisconsin.


Fmt Placed By Colonoscopy: Systematic Review And Meta-Analysis, Nadia Huq, Veena Kumaravel, Aboud Affi, Maharaj Singh 2017 Department of Internal Medicine, Aurora Sinai Medical Center

Fmt Placed By Colonoscopy: Systematic Review And Meta-Analysis, Nadia Huq, Veena Kumaravel, Aboud Affi, Maharaj Singh

Journal of Patient-Centered Research and Reviews

Background: Fecal transplants are successful in the treatment of recurrent or refractory Clostridium difficile infections (CDI), but there is no consensus on the best method of instillation. Studies have shown greater success with lower gastrointestinal tract placement, but technical aspects of placement are not validated.

Purpose: This review aims to identify common traits and procedural techniques of successful fecal microbiota transplant (FMT) therapy via colonoscopy.

Methods: An electronic search was conducted using OVID Medline and PubMed for articles published from January 2010 to January 2016. The primary outcome of interest was cure by FMT placed via colonoscopy.

Results: Of the ...


A Retrospective Study Evaluating Endoscopic Ultrasound-Guided Drainage Of Pancreatic Fluid Collections Using A Novel Lumen-Apposing Metal Stent On An Electrocautery Enhanced Delivery System., Douglas G. Adler, Linda Jo Taylor, Raza Hasan, Ali A. Siddiqui 2017 University of Utah Hospital

A Retrospective Study Evaluating Endoscopic Ultrasound-Guided Drainage Of Pancreatic Fluid Collections Using A Novel Lumen-Apposing Metal Stent On An Electrocautery Enhanced Delivery System., Douglas G. Adler, Linda Jo Taylor, Raza Hasan, Ali A. Siddiqui

Division of Gastroenterology and Hepatology Faculty Papers

OBJECTIVES: To report the safety and clinical efficacy with the novel lumen-apposing metal stent (LAMS) with an electrocautery enhanced delivery system for the drainage of pancreatic fluid collections (PFCs).

METHODS: This was a retrospective analysis of all consecutive patients with PFCs who underwent endoscopic ultrasound (EUS)-guided drainage using the LAMS with an electrocautery enhanced delivery system in 2 US centers.

RESULTS: Thirteen patients with PFCs (69% with walled-off necrosis [WON]) underwent drainage using the study device. Successful stent placement was accomplished in all patients. Direct endoscopic necrosectomy was carried out in all nine patients with WON complete resolution of ...


Retrospective Review Of Biofires Filmarray Gastrointestinal Panels Detection Of Multiple Pathogens In Adults Patients., Patrick Hickey DO, Eric Nellis MD, Anastasia Shnitser MD, Amy Slenker MD 2017 Lehigh Valley Health Network

Retrospective Review Of Biofires Filmarray Gastrointestinal Panels Detection Of Multiple Pathogens In Adults Patients., Patrick Hickey Do, Eric Nellis Md, Anastasia Shnitser Md, Amy Slenker Md

Department of Medicine

No abstract provided.


Gucy2c Maintains Intestinal Lgr5+ Stem Cells By Opposing Er Stress, Crystal Kraft, Jeff A. Rappaport, Adam E. Snook, Amanda M. Pattison, John P. Lynch, Scott A. Waldman 2017 Thomas Jefferson University

Gucy2c Maintains Intestinal Lgr5+ Stem Cells By Opposing Er Stress, Crystal Kraft, Jeff A. Rappaport, Adam E. Snook, Amanda M. Pattison, John P. Lynch, Scott A. Waldman

Department of Pharmacology and Experimental Therapeutics Faculty Papers

Long-lived multipotent stem cells (ISCs) at the base of intestinal crypts adjust their phenotypes to accommodate normal maintenance and post-injury regeneration of the epithelium. Their long life, lineage plasticity, and proliferative potential underlie the necessity for tight homeostatic regulation of the ISC compartment. In that context, the guanylate cyclase C (GUCY2C) receptor and its paracrine ligands regulate intestinal epithelial homeostasis, including proliferation, lineage commitment, and DNA damage repair. However, a role for this axis in maintaining ISCs remains unknown. Transgenic mice enabling analysis of ISCs (Lgr5-GFP) in the context of GUCY2C elimination (Gucy2c-/-) were combined with immunodetection techniques and pharmacological ...


Duodenal Varices: A Rare Cause Of Gastrointestinal Bleeding., Anam Malik MD, Abdul Aleeem MD, Eric Nellis MD, Hiral N. Shah MD 2017 Lehigh Valley Health Network

Duodenal Varices: A Rare Cause Of Gastrointestinal Bleeding., Anam Malik Md, Abdul Aleeem Md, Eric Nellis Md, Hiral N. Shah Md

Department of Medicine

No abstract provided.


Initial Experience Of A Community Gastroenterology Practice With Ultra-Slim Colonoscopy: A Case Series., Rajesh Essrani MD, Patrick Hickey DO, Hiral N. Shah MD, Paola Blanco MD 2017 Lehigh Valley Health Network

Initial Experience Of A Community Gastroenterology Practice With Ultra-Slim Colonoscopy: A Case Series., Rajesh Essrani Md, Patrick Hickey Do, Hiral N. Shah Md, Paola Blanco Md

Department of Medicine

No abstract provided.


Unusual Case Of Obstructive Jaundice., Rajesh Essrani MD, Eric Nellis MD, Patrick Hickey DO, Hiral N. Shah MD 2017 Lehigh Valley Health Network

Unusual Case Of Obstructive Jaundice., Rajesh Essrani Md, Eric Nellis Md, Patrick Hickey Do, Hiral N. Shah Md

Department of Medicine

No abstract provided.


Role Of 68ga-Dodatate Pet/Ct In Staging And Management Of Gastroenteropancreatic Neuroendocrine Tumor Management - A Case Series Report., Abdul Aleem MD, Patrick Hickey DO, Shashin Shah MD, Hiral N. Shah MD 2017 Lehigh Valley Health Network

Role Of 68ga-Dodatate Pet/Ct In Staging And Management Of Gastroenteropancreatic Neuroendocrine Tumor Management - A Case Series Report., Abdul Aleem Md, Patrick Hickey Do, Shashin Shah Md, Hiral N. Shah Md

Department of Medicine

No abstract provided.


No Gastrointestinal Bleed Too Obscure: A Case Series Report Of Small Bowel Phlebectasias., Abdul Aleem MD, Anam Malik MD, Patrick Hickey DO, Anastasia Shnitser MD 2017 Lehigh Valley Health Network

No Gastrointestinal Bleed Too Obscure: A Case Series Report Of Small Bowel Phlebectasias., Abdul Aleem Md, Anam Malik Md, Patrick Hickey Do, Anastasia Shnitser Md

Department of Medicine

No abstract provided.


Angiocatheter Guided Closure Of Gastrocutaneous Fistula Tract In The Absence Of Fluoroscopy, Travis Magdaleno MD, Hiral N. Shah MD, Shashin Shah MD 2017 Lehigh Valley Health Network

Angiocatheter Guided Closure Of Gastrocutaneous Fistula Tract In The Absence Of Fluoroscopy, Travis Magdaleno Md, Hiral N. Shah Md, Shashin Shah Md

Department of Medicine

No abstract provided.


Development Of Pancreatic Cancer During Novel Therapy For Head And Neck Cancer With Pembrolizumab: A Case Report, Travis Magdaleno MD, Patrick Hickey DO, Shashin Shah MD, Hiral N. Shah MD 2017 Lehigh Valley Health Network

Development Of Pancreatic Cancer During Novel Therapy For Head And Neck Cancer With Pembrolizumab: A Case Report, Travis Magdaleno Md, Patrick Hickey Do, Shashin Shah Md, Hiral N. Shah Md

Department of Medicine

No abstract provided.


Epstein-Barr Virus Mucocutaneous Colonic Ulcer In An Immunocompetent Patient., Travis Magdaleno MD, Eric Nellis MD, Paola Blanco MD 2017 Lehigh Valley Health Network

Epstein-Barr Virus Mucocutaneous Colonic Ulcer In An Immunocompetent Patient., Travis Magdaleno Md, Eric Nellis Md, Paola Blanco Md

Department of Medicine

No abstract provided.


The Use Of Palliative Performance Score In Patients With End-Stage Liver Disease, Drew Kotler, MD, Mital Shah, MD, Sheela S. Reddy, MD, Jonathan M. Fenkel, MD, John Liantonio, MD, Dina Halegoua-De Marzio, MD 2017 Thomas Jefferson University

The Use Of Palliative Performance Score In Patients With End-Stage Liver Disease, Drew Kotler, Md, Mital Shah, Md, Sheela S. Reddy, Md, Jonathan M. Fenkel, Md, John Liantonio, Md, Dina Halegoua-De Marzio, Md

Department of Medicine Posters

● Palliative Care services are often underutilized in patients with End-Stage Liver Disease (ESLD) and often only initiated at the end of life

● The Palliative Performance Score (PPS) is an important tool used in Palliative Care to assess functional status

● PPS has five functional dimensions: ambulation, activity level and evidence of disease, self-care, oral intake, and level of consciousness

● The aim of this study is to determine if there is a correlation between Model for End-Stage Liver Disease (MELD) score and PPS in ESLD patients

● MELD is used to predict mortality and to prioritize liver transplant allocation in ESLD patients


Amoebic Brain Abscess Associated With Renal Cell Carcinoma, Umme Hani Abdullah,, Mirza Zain Baig,, Muhammad Azeemuddin,, Mohammad Wasay,, javed Yakoob, Mohammad Asim Beg 2017 Aga Khan University

Amoebic Brain Abscess Associated With Renal Cell Carcinoma, Umme Hani Abdullah,, Mirza Zain Baig,, Muhammad Azeemuddin,, Mohammad Wasay,, Javed Yakoob, Mohammad Asim Beg

Section of Gastroenterology

Entamoeba histolytica is a protozoan parasite that is associated with diarrhea, but can extend to involve several organs. We report a case of amoebic brain abscess in a man who presented with fever, vomiting and headache with confusion and right hemiparesis. Brain magnetic resonance imaging showed a mass in the left frontal lobe, while abdominal computerized tomography showed a left renal malignancy. Brain biopsy showed Entamoeba histolytica infection. He was treated with intra- venous metronidazole and nephrectomy that was followed by complete recovery. The present case report emphasizes that cerebral amoebiasis is associated with renal cell carcinoma.


Black Esophagus With Superimposed Candida In A Patient With B Cell Lymphoma: A Case Study., Christopher Lenivy DO, Patrick Hickey DO, Adam Peyton DO 2017 Lehigh Valley Health Network

Black Esophagus With Superimposed Candida In A Patient With B Cell Lymphoma: A Case Study., Christopher Lenivy Do, Patrick Hickey Do, Adam Peyton Do

Department of Medicine

No abstract provided.


Quality Assessment Of The Efficacy And Cost-Effectiveness Of Fecal Microbiota Transplant For Recurrent Clostridium Dfficile Infection., Eric Nellis MD, Shashin Shah MD 2017 Lehigh Valley Health Network

Quality Assessment Of The Efficacy And Cost-Effectiveness Of Fecal Microbiota Transplant For Recurrent Clostridium Dfficile Infection., Eric Nellis Md, Shashin Shah Md

Department of Medicine

No abstract provided.


Digital Commons powered by bepress