Surgery Commons^™

3d Printing Of Bone Spurs Before Surgical Removal, Matthew Chadwick, John Paul Prodoehl, Katelyn Koons, Chris Li, Lauren Schlegel, Jeffrey Henstenburg, Md

Phase 1

Project Background: In the US alone, total knee arthroplasty is the most common performed orthopedic surgery, with over 700,000 cases per year.1 Overall, 21-25% underwent revision due to instability.2 The stability of a TKA depends largely on soft tissue balance for proper alignment in flexion and extension. Soft tissue balancing in TKA depends on posterior femoral condylar osteophytes, which prevent full extension of the knee and increase tension posteriorly. Pre-operative soft tissue visualization is difficult and this leaves an increased chance for implant failure and revision surgery. Having a 3D model of the bone spur before and during the surgery …

Rescue Stenting For Failed Mechanical Thrombectomy Procedures, Joseph Schaefer, Ahmad Sweid, Md, M. Reid Gooch, Md, Pascal Jabbour, Md

Phase 1

Background: Mechanical thrombectomy (MT) has dramatically changed the natural history of acute ischemic stroke. The disease that was associated with high morbidity, mortality, and significant cost on the health care system became a treatable disease. One of the most important variables to improve outcomes is time to revascularize the ischemic tissue. Rescue stenting (RS) is an option for patients who fail MT.

Methods: A retrospective chart review for patients who underwent a MT procedure and either failed (defined as TICI 0-2a) or required a RS from 2015 – 2019 composed the study population. IRB approval was obtained and the consent …

Renewing Hearts: Catholic Perspectives In Valve Replacement Surgery For Those Who Use Intravenous Drugs, Kimberly Feeney, Robert Perkel, Md

Phase 1

Introduction: The incidence of infectious endocarditis has been increasing, particularly among those with a history of intravenous drug use (IVDU). Although current bioethics literature supports valve surgery as treatment for this patient population, clinical guidelines and literature continues to provide unclear recommendations for physicians. Catholic bioethics may provide a different perspective to re-contextualize the recommendations of secular ethics.

Methods: A PubMed search was used to gain background information regarding the incidence of infectious endocarditis and current treatment guidelines, as well as historical and current ethical considerations. Search terms included: “infectious endocarditis,” “IE,” “intravenous drug use,” “IVDU,” “ethics.” Related citations were …

Investigation Of Molecular Mechanisms Of Liver Preservation Injury: A Complication Preceding Organ Transplantation, Ria C. Fyffe-Freil

Theses and Dissertations

Of the over 108,000 American awaiting a life-saving organ transplant today, over 12,000 (11%) of those need a new liver (OPTN, 2020). Last year, only 35% of patients on the waiting list for an organ were transplanted. Improving the quality of marginal organs by preventing or reversing preservation injury could vastly increase the number of transplants performed. Washout of circulating blood during liver procurement with cold University of Wisconsin solution flushes out any endogenous pro-survival signaling molecules. We investigated lysophospholipid (LPL) surface receptors (G-protein coupled receptors for lysophosphatidic acid (LPA) and sphingosine- 1-phosphate (S1P)) and their role in protecting hepatocytes …

Prospective Molecular Profiling Of Circulating Tumor Cells From Patients With Melanoma Receiving Combinatorial Immunotherapy., Selena Y Lin, Shu-Ching Chang, Stella Lam, Romela Irene Ramos, Kevin Tran, Shuichi Ohe, Matthew P Salomon, Ali Asgar S Bhagat, Chwee Teck Lim, Trevan D Fischer, Leland J Foshag, Christine L Boley, Steven J O'Day, Dave Hoon

Articles, Abstracts, and Reports

BACKGROUND: Blood molecular profiling of circulating tumor cells (CTCs) can enable monitoring of patients with metastatic melanoma during checkpoint inhibitor immunotherapy (CII) and in combination with targeted therapies. We developed a microfluidics-based CTC platform to explore CTC profiling utility in CII-treated patients with melanoma using a melanoma messenger RNA (mRNA)/DNA biomarker panel.

METHODS: Blood samples (n = 213) were collected prospectively from 75 American Joint Committee on Cancer-staged III/IV melanoma patients during CII treatment and those enriched for CTCs. CTC profiling was performed using 5 known melanoma mRNA biomarkers and BRAF V600E DNA mutation. CTC biomarker status associations with clinical …

Conservative Treatment Of Grade Iii Acromioclavicular Joint Dislocation, Islam Hashim, Emad Zayed

Al-Azhar International Medical Journal

Abstract Background: The acromio-clavicular (AC) joint stability depends on the acromio-clavicular ligaments, the coraco-clavicular (CC) ligaments,and the joint capsule. Treatment of acute type III injuries still controversial We evaluated the results of conservative treatment of type III AC joint dislocation according to clinical and radiological outcome. Patients and Methods: This prospective study included fifteen patients with acute acromio-clavicular joint dislocations type III. There were one woman and fourteen men, with an average age of 29.7 ±10.2 years. All patients underwent clinical assessment according to Constant score and a radiographic study (antero-posterior showing both shoulders, axillary views).All patients were treated conservatively …

Effect Of High Volume Hemodiafiltration On Secondary Hyperparathyroidism Among Hemodialysis Patients, Ahmed Alsawy

Al-Azhar International Medical Journal

Abstract Background: Despite increasing knowledge of the uraemic syndrome,both morbidity and mortality remain unacceptably high in patients with chronic kidney disease. Study investigates the differences between conventional hemodialysis and hemodiafiltration in the context of chronic kidney disease metabolic bone disease findings, serum calcium (sCa), phosphate (sPO4) and intact parathyroid hormone (PTHint) concentrations. Patients and methods: This prospective cross over study was approved by Almaadi hospital committee and included 95patients with CKD5 on regular hemodialysis for at least 6months.Patients were divided into two groups:Group A:60patients scheduled 6months conventional high flux(hf-HD)(Period1) followed by 6months of post-dilutional –HDF (Period2). Group B:(controls)included 35patients were …

Combined Anterior Cruciate Ligament Reconstruction And High Tibial Osteotomy In Anterior Cruciate Ligament-Deficient Varus Knees, Hamed Mohammed

Al-Azhar International Medical Journal

Background: The presence of varus deformity in anterior cruciate ligament (ACL)-deficient knees can be a source of persistent knee pain owing to medial compartment overload. This deformity may threaten the outcome of ACL reconstruction because of increased tension on the graft. Methods: In the period between May 2018 to september 2019, short term pilot study including 10 patients with ACL deficiency and genu varus were treated by anatomical single bundle ACL reconstruction and open medial wedge high tibial osteotomy in same sitting. The selected patients had manifestations of ACL deficiency in association with medial joint line pain with or without …

Changes Of Corneal Topographic Measurements And Refractive Errors After Horizontal Muscle Surgery. A Case Series, Nour Elwakeel

Al-Azhar International Medical Journal

Abstract Background: Refractive and corneal topographic changes after routine strabismus surgery have been reported and can occur even after a successful surgery. Study aims to evaluate the effect of horizontal muscle surgery on refractive errors and corneal measurements. Patients and methods: This study includes 25 eyes of 22 patients who have manifest strabismus. The patients were divided into two groups. Group A (10 eyes of 7 patients) subjected to unilateral lateral rectus recession. Group B (15 eyes of 15 patients) all of them subjected to lateral rectus recession and medial rectus resection in the same eye. Cycloplegic automated refraction (including …

Age Related Changes In The Expression Of Tenascin-C In Liver Of Albino Rat, Mohammed Mohammed, Mohammed Mokhtar El Assaly, Hamdino Attia

Al-Azhar International Medical Journal

Abstract Background: Aging is a gradual deterioration in the function of tissues and organ systems with loss of the ability to maintain homeostasis, due to structural alteration or dysfunction. Aging impact directly on all the different types of liver cells: hepatocytes, liver sinusoidal endothelial cells (LSECs), Küpffer cells (KCs) and hepatic stellate cells (HSCs). Activation of HSCs leads to deposition of collagen in the space of Disse, decrease of fenestrations of LSECs and formation of basement membrane. These changes called pseudocapillarization. Tenascin-C (TN-C) is an extracellular matrix glycoprotein markedly up-regulated during liver fibrosis. Tenascin-C is highly expressed during embryonic development, …

Endometrial Flushing Versus Endometrial Brush Cytology In High Risk Women For Endometrial Carcinoma, Abdullah Mokbel

Al-Azhar International Medical Journal

Background: Postmenopausal bleeding (PMB), defined as blood loss occurring at least 12 months after menopause, is a common complaint in general gynecological practice. The prevalence of PMB is approximately 10% immediately after menopause. Aim of work: This study aims to compare between two diagnostic methods Flush and Brush cytology. Patients and Methods: The study population comprises eighty (80) women with postmenopausal bleeding, was conducted over 12 months from April 2018, to April 2019 on postmenopausal women who were approached, managed and followed up in the Gynecology Clinic of Minia General Hospital to compare between two diagnostic methods Flush and Brush …

A Comparative Study Between Snodgrass And Urethral Advancement Methods In The Repair Of Distal Penile Hypospadias, Yassin Alngaar, Osama Alshahat, Tarek Zayid

Al-Azhar International Medical Journal

Background: Numerous original methods have been introduced to repair hypospadias with variable results. Aim of The Work: The aim of this work is to evaluate the two techniques, Snodgrass and anterior urethral advancement for the repair of distal hypospadias. Materials and Methods: A total of, 16 patients with distal hypospadias underwent primary repair in a prospective controlled randomized trial. Eight patients were allocated for a Snodgrass procedure and another 8 patients were allocated for a urethral advancement procedure. A comparative study was conducted, and the outcome was evaluated in terms of satisfactory functional and cosmetic outcomes. The study was done …

Oophorectomy, Ashli A. Lawson, Rebecca M. Rentea

Manuscripts, Articles, Book Chapters and Other Papers

Oophorectomy is the surgical removal of the ovary and can be unilateral or bilateral. Hysterectomy is the most common major gynecologic surgery, but salpingo-oophorectomy remains a frequent concomitant surgery. Surgery for ovarian pathology alone is still often encountered in females of all ages. While surgical removal of one ovary does not grossly affect the hormonal milieu of a patient, bilateral oophorectomy will render a patient infertile and menopausal with ensuing physiologic changes and risks. Forward-thinking discussions should be held with the patient before undertaking an oophorectomy.

Retroperitoneal Hematoma, Christopher Mondie, Rebecca M. Rentea

Manuscripts, Articles, Book Chapters and Other Papers

Retroperitoneal hematoma is defined as bleeding into the retroperitoneal space. This clinical entity is often occult and under-recognized by clinicians and is a cause of significant morbidity and mortality. Often patients do not manifest clinically apparent signs and symptoms until a substantial amount of blood loss has occurred. It is not uncommon for patients to present in frank hemorrhagic shock due to an underlying retroperitoneal hematoma. The retroperitoneal space lies directly posterior to the peritoneal cavity. An organizational schema dividing the retroperitoneal space into three different “zones” is widely prevalent in the surgical literature. The central-medial zone (Zone I) falls …

Risk Of Recurrent Laryngeal Nerve Injury In Complete Resection Of Recurrent Multi-Nodular Goiter, Khalid Elkhateeb, Amr Elgohary, Mohamed Sharaf

Al-Azhar International Medical Journal

Background: Anatomic and functional preservation of the recurrent laryngeal nerve (RLN) is the gold standard in thyroid and various neck surgery. Aim of the work: To assess incidence and risk factors for (RLN) injury which may be just palsy or permanent injury postoperative after thyroid surgery in patient with recurrent multiple nodular goiter (MNG) and observe the timing of recovery. Methods: This prospective cross-sectional study was done on fifty patients with recurrent MNG. The study was done from December 2018 to October 2019. Patients with voice changes, RLN injury from previous operation and other type of cancer thyroid were excluded …

Echocardigraphic Assessment Of Right Ventricular Outflow Tract Function In Patients With Chronic Heart Failure, Ehab Alhefny, Yasser Abdelgaleel, Mostafa Saleh

Al-Azhar International Medical Journal

ABSTRACT Background: Heart failure (HF) is a progressive , clinical disease where a subset of HF patients has symptoms unrelated to the hemodynamic status and left ventricular ejection fraction . The Right ventricular (RV) function is considered to be a reliable prognostic element in HF, although assessing it is a challenge because of the complexity of the RV. Objective: This study aimed to investigate the clinical application of RV outflow tract (RVOT) function measured by transthoracic echocardiography in HF patients. Method: The investigation of 80 chronic HF patients with dilated dimensions and left ventricular systolic dysfunction (EF less than 40%) …

Evaluation Of Surgical Management Of Spondylolithesis In Osteoporotic Patients

Al-Azhar International Medical Journal

Background: Osteoporosis has become a major medical problem as the aged population of the world rapidly grows. Aim of the Work: We aimed to assess different methods of surgical treatment of Spondylolithesis in osteoprotic patients. Patient and methods: This prospective study was conducted on 30 cases with spondylolithesis and osteoporosis at Al-Azhar university hospitals. All patients were operated upon by posterior approach with neural decompression and internal metallic fixation. Results: The percentage of improvement (6.7%), fair (33.3%), good (46.7%), excellent (13.3%) of low back pain, also Fair (6.7%), good (33.3%),Excellent (60.0%) of Sciatica; good (50.0%), excellent (50.0%) of claudication; while …

Original Article Template For Al-Azhar International Medical Journal: Academic Witting To A Scientific Journal, Yasser Helmy

Al-Azhar International Medical Journal

This Article is an Editor-in-Chief Lecture. It will help you to understand a lot of Knowledge about Academic writing and preparation of a scientific article to Al-Azhar International Medical Journal (AIMJ) or any other Journal worldwide. It describes the requirements of Academic writing in details. It provides so many of tips for perfect structuring of the Article, that would make a scientific work ready for primary acceptance by most of editors, if really followed up.

Evaluation Of The Role Of Fecal Microbiota Transplantation In The Management Of Ulcerative Colitis In Egyptian Patients, Ahmed Ahmed, Gamal Soliman, Mohei Eldin Amer

Al-Azhar International Medical Journal

Background and Aims: Fecal Microbiota Transplantation (FMT) is a novel form of therapeutic microbial manipulation aims to restore the intestinal microbiota in diseased individuals by transferring intestinal microbiota of healthy donors. We aimed to establish the efficacy of, multi donor, fecal microbiota transplantation in active ulcerative colitis(UC) in Egyptian patients. Subjects and Methods: known UC patients (n-50) were divided in two groups, Group one included 25 patients who treated with medical treatment alone and then follow up was done for 24 weeks. Group two included 25 patients who treated with medical treatment and underwent FMT via complete colonoscopy every three …

Commentary On: Cosmeceuticals: The Principles And Practice Of Skin Rejuvenation Of Nonprescription Topical Therapy, Clifford P. Clark, Ashley Goldston

Surgery Faculty Publications

No abstract provided.