Influence Of Extracellular Volume Fraction On Peak Exercise Oxygen Pulse Following Thoracic Radiotherapy, 2022 Virginia Commonwealth University
Influence Of Extracellular Volume Fraction On Peak Exercise Oxygen Pulse Following Thoracic Radiotherapy, Justin M. Canada, Elisabeth Weiss, John D. Grizzard, Cory R. Trankle, Leila Rezai Gharai, Franklin Dana, Leo F. Buckley, Salvatore Carbone, Dinesh Kadariya, Anthony Ricco, Jennifer H. Jordan, Ronald K. Evans, Ryan S. Garten, Benjamin W. Van Tassell, W. Gregory Hundley, Antonio Abbate
Internal Medicine Publications
Background
Radiation-induced myocardial fibrosis increases heart failure (HF) risk and is associated with a restrictive cardiomyopathy phenotype. The myocardial extracellular volume fraction (ECVF) using contrast-enhanced cardiac magnetic resonance (CMR) quantifies the extent of fibrosis which, in severe cases, results in a noncompliant left ventricle (LV) with an inability to augment exercise stroke volume (SV). The peak exercise oxygen pulse (O2Pulse), a noninvasive surrogate for exercise SV, may provide mechanistic insight into cardiac reserve. The relationship between LV ECVF and O2Pulse following thoracic radiotherapy has not been explored.
Methods
Patients who underwent thoracic radiotherapy for chest malignancies with significant incidental heart …
Calpain-Mediated Protein Targets In Cardiac Mitochondria Following Ischemia–Reperfusion, 2022 Cleveland Clinic
Calpain-Mediated Protein Targets In Cardiac Mitochondria Following Ischemia–Reperfusion, Ling Li, Jeremy Thompson, Ying Hu, Edward J. Lesnefsky, Belinda Willard, Qun Chen
Internal Medicine Publications
Calpain 1 and 2 (CPN1/2) are calcium-dependent cysteine proteases that exist in cytosol and mitochondria. Pharmacologic inhibition of CPN1/2 decreases cardiac injury during ischemia (ISC)–reperfusion (REP) by improving mitochondrial function. However, the protein targets of CPN1/2 activation during ISC–REP are unclear. CPN1/2 include a large subunit and a small regulatory subunit 1 (CPNS1). Genetic deletion of CPNS1 eliminates the activities of both CPN1 and CPN2. Conditional cardiomyocyte specific CPNS1 deletion mice were used in the present study to clarify the role of CPN1/2 activation in mitochondrial damage during ISC–REP with an emphasis on identifying the potential protein targets of CPN1/2. …
Pocus Use In Skin And Soft Tissue Infections: A Case Series, 2022 Providence
Pocus Use In Skin And Soft Tissue Infections: A Case Series, Kyle Davies, Sam Josephsen, Vanessa Hoytfox
View All Washington/Montana GME
Presented at the 2022 Virtual Northwest Medical Research Symposium
Clinical Factors Implicated In Antibiotic Resistance In Helicobacter Pylori Patients, 2022 Cooper Medical School of Rowan University
Clinical Factors Implicated In Antibiotic Resistance In Helicobacter Pylori Patients, Brian White, Maria Winte, Joshua Desipio, Sangita Phadtare
Division of Internal Medicine Faculty Papers & Presentations
Helicobacter pylori is a common gastric pathogen associated with multiple clinical syndromes, including cancer. Eradication rates of H. pylori remain suboptimal despite the progress made in the past few decades in improving treatment strategies. The low eradication rates are mainly driven by antibiotic resistance of H. pylori. Non-invasive molecular testing to identify patients with antibiotic-resistant H. py-lori represents a promising therapeutic avenue, however this technology currently remains limited by availability, costs, and lack of robust validation. Moreover, there is insufficient evidence to demonstrate that resistance-testing-based treatment approaches are superior to appropriately designed empiric strat-egies. Consensus guidelines recommend use of proven …
Dermatologic Manifestations Of Rheumatic Disease: Cutaneous Manifestations Of Sarcoidosis, 2022 Virginia Commonwealth University
Dermatologic Manifestations Of Rheumatic Disease: Cutaneous Manifestations Of Sarcoidosis, Sarah Shapiro, Sindhuja Koppu, Mavra Masood, Beth Rubinstein, Huzaefah Syed
Open and Affordable Course Content at VCU
Cutaneous Manifestations of Sarcoidosis is a Powerpoint based learning module that depicts fictional patient scenarios detailing sarcoidosis and erythema nodosum. It explores other cutaneous and non-cutaneous manifestations, diagnostic criteria, and medical evaluation of sarcoidosis and the possible etiologies, workup, treatment, and prognosis of erythema nodosum. Health and racial disparities experienced by patients with sarcoidosis are also highlighted and discussed. It takes approximately 25 minutes to complete. This module was created for use in the VCU School of Medicine M1 Movement block, Rheumatology and Dermatology sections.
It is part of the Dermatologic Manifestations of Rheumatic Disease project, which provides overviews of …
Eliminating Repetitive Cbc Orders On The Resident Inpatient Service At Orlando Vahcs, 2022 HCA Healthcare
Eliminating Repetitive Cbc Orders On The Resident Inpatient Service At Orlando Vahcs, Zara Bashir, Jorge Rodriguez, Ashlee Sidhu, Feras Al-Moussally, Brian Murr, Jorge Restrepo
North Florida Division Research Day 2022
No abstract available.
Not Just An Accident: A Case Of Insulinoma, 2022 HCA Healthcare
Not Just An Accident: A Case Of Insulinoma, Asanka Ekanayake, Harrison Stubbs, Dominique Broutin, Olga Karasik, Mustafa Kinaan
North Florida Division Research Day 2022
No abstract available.
Triple Sars-Cov2, Influenza A & Influenza B Co-Infection, 2022 HCA Healthcare
Triple Sars-Cov2, Influenza A & Influenza B Co-Infection, Feras Al-Moussally, Mohammed Rahhal, Rey Marrero, Roger Crouse
North Florida Division Research Day 2022
No abstract available.
Case Report: Disseminated Mucormycosis In An Ostensibly Immunocompetent Patient, 2022 HCA Healthcare
Case Report: Disseminated Mucormycosis In An Ostensibly Immunocompetent Patient, Chad Froes, Matt Gellatly, Brian Watson
South Atlantic Division Research Day 2022
No abstract provided.
The Ctsa University Of Texas Health Science Center (Uthsc) Northeast-Tyler And Rio Grande Valley Success Story: How Rural, Underserved Academic Communities Rapidly Built A Robust Engine For Collaborative Covid-19 Clinical Research, 2022 The Texas Medical Center Library
The Ctsa University Of Texas Health Science Center (Uthsc) Northeast-Tyler And Rio Grande Valley Success Story: How Rural, Underserved Academic Communities Rapidly Built A Robust Engine For Collaborative Covid-19 Clinical Research, Steven Idell, David D Mcpherson, Jessica Martin, Andrew Dentino, Luis Ostrosky-Zeichner, Julia V Philley, Paul Mcgaha, Megan Devine, Jacqueline Bronicki, Daniel D Karp
Journal Articles
In 2018, The University of Texas Health Science Center-Tyler and University of Texas Rio Grande Valley were invited to develop clinical research units for an existing Clinical and Translational Science Award (CTSA) consortium with the objective to equip medically underserved, economically disadvantaged communities and subsequently to deploy COVID-19 clinical trials in response to a public health emergency.
Optimizing Secure Patient Messaging Workflow In A Vermont Primary Care Clinic, 2022 University of Vermont
Optimizing Secure Patient Messaging Workflow In A Vermont Primary Care Clinic, Kimberly S. Oleary
College of Nursing and Health Sciences Doctor of Nursing Practice (DNP) Project Publications
Optimizing Secure Patient Messaging Workflow in a Vermont Primary Care Clinic
Kim O’Leary, DNPc, RN
DNP Advisor: Margaret Aitken, DNP, AGNP, ANP-BC
Site Mentor: James Williamson, MHA, Site Supervisor, Adult Primary Care
Background: Secure patient messaging is a popular tool designed for non-urgent questions, yet patients sometimes use it to relay urgent concerns. As office workflows tend to prioritize responses to other methods of communication, this presents a potentially unsafe situation in which clinical staff may not respond to these urgent messages in a timely manner.
Purpose: To develop a methodology to improve the timeliness, effectiveness, and safety of secure …
Unusual Case Of Isolated Pancreatitis Secondary To Blunt Abdominal Trauma, 2022 HCA Healthcare
Unusual Case Of Isolated Pancreatitis Secondary To Blunt Abdominal Trauma, Haroutiun Hamzoian, Reuben Plasencia, Ndifreke Ekpa, Elias Georg
Gulf Coast Division Research Day 2022
No abstract provided.
A Rare Case Of Splenic Artery Thrombosis Provoked By Medroxyprogesterone Acetate (Dmpa) Requiring Splenectomy, 2022 HCA Healthcare
A Rare Case Of Splenic Artery Thrombosis Provoked By Medroxyprogesterone Acetate (Dmpa) Requiring Splenectomy, Raghav Bassi, Asad Haider, Pranav Prakash, Abdullahi Hussein, Hamza Alzghoul, Muhammad Bilal, Anuoluwa Oyetoran, Uma Iyer
North Florida Division Research Day 2022
No abstract available.
A Case Of Neuroparacoccidioidomycosis In Houston, Texas, 2022 The Texas Medical Center Library
A Case Of Neuroparacoccidioidomycosis In Houston, Texas, Maitreyi Narayan, Swetha Jayavelu, Harsh Goel, Joshua R Rosenthal, Gabriel M Aisenberg
Journal Articles
Paracoccidioidomycosis is a systemic fungal disease caused by the dimorphic
Exploring The Feasibility Of Virtually Delivered Auricular Point Acupressure In Self-Managing Chronic Pain: Qualitative Study, 2022 The Texas Medical Center Library
Exploring The Feasibility Of Virtually Delivered Auricular Point Acupressure In Self-Managing Chronic Pain: Qualitative Study, Jennifer Kawi, Chao Hsing Yeh, Nada Lukkahatai, Robin L Hardwicke, Thomas Murphy, Paul J Christo
Journal Articles
BACKGROUND: Chronic pain remains highly prevalent. Current pharmacological and non-pharmacological strategies have not adequately managed chronic pain which has contributed to disability and high healthcare costs. With existing challenges in providing adequate pain care and access, we tested vAPA, a virtually delivered, self-management intervention using Auricular Point Acupressure (APA) by mobile app and virtual consultations (telehealth). Our key purpose was to evaluate the feasibility of the vAPA in self-managing chronic pain in preparation for a future randomized controlled trial.
METHODS: We conducted a descriptive, qualitative study evaluating our 4-week vAPA intervention among 18 participants. We used directed qualitative content analysis.
Evaluation Of Medical Services From The Perspective Of Covid-19 Vaccine Demand Satisfaction In Hangzhou, China., 2022 The Texas Medical Center Library
Evaluation Of Medical Services From The Perspective Of Covid-19 Vaccine Demand Satisfaction In Hangzhou, China., Mingjun Cheng, Yunchen Zhu, Peili Cen, Shan Huang
Journal Articles
The outbreak of COVID-19 has had a huge global impact, and it continues to test the resilience of medical services to emergencies worldwide. In the current post-epidemic era, vaccination has become a highly effective strategy to prevent the spread of COVID-19. However, using conventional mathematical models to evaluate the spatial distribution of medical resources, including vaccination, ignore people's behaviors and choices and make simplifications to the real world. In this study, we use an enhanced model based on the Theory of People Behavior (TPB) to perform a macro analysis of the satisfaction ability of medical resources for vaccination in Hangzhou, …
A Message From The Trench: A Day In The Hospital During The Covid-19 Pandemic, 2022 The Texas Medical Center Library
A Message From The Trench: A Day In The Hospital During The Covid-19 Pandemic, Gabriel M Aisenberg
Journal Articles
No abstract provided.
Trigger Related Outcomes Of Takotsubo Syndrome In A Cancer Population., 2022 The Texas Medical Center Library
Trigger Related Outcomes Of Takotsubo Syndrome In A Cancer Population., Ayesha Safdar, Talha Ahmed, Victor Y Liu, Antoine Addoumieh, Ali M Agha, Dana E Giza, Dinu V Balanescu, Teodora Donisan, Tariq Dayah, Juan C Lopez-Mattei, Peter Y Kim, Saamir Hassan, Kaveh Karimzad, Nicolas Palaskas, January Y Tsai, Gloria D Iliescu, Eric H Yang, Joerg Herrmann, Konstantinos Marmagkiolis, Paolo Angelini, Cezar A Iliescu
Journal Articles
BACKGROUND: Takotsubo syndrome (TTS) occurs more frequently in cancer patients than in the general population, but the effect of specific TTS triggers on outcomes in cancer patients is not well studied.
OBJECTIVES: The study sought to determine whether triggering event (chemotherapy, immune-modulators vs. procedural or emotional stress) modifies outcomes in a cancer patient population with TTS.
METHODS: All cancer patients presenting with acute coronary syndrome (ACS) between December 2008 and December 2020 at our institution were enrolled in the catheterization laboratory registry. Demographic and clinical data of the identified patients with TTS were retrospective collected and further classified according to …
Implementing A Robust Process Improvement Program In The Neonatal Intensive Care Unit To Reduce Harm, 2022 The Texas Medical Center Library
Implementing A Robust Process Improvement Program In The Neonatal Intensive Care Unit To Reduce Harm, Klaus G Nether, Eric J Thomas, Amir Khan, Madelene J Ottosen, Lauren Yager
Journal Articles
INTRODUCTION: Preventable harm continues to occur with critically ill neonates despite efforts by hospital neonatal intensive care units (NICUs) to improve processes and reduce harm. Attaining significant and sustainable improvements will require training including leadership support, mentoring, and patient family engagement to improve care processes. This paper describes the implementation of a robust process improvement (RPI) program in the NICU to reduce harm.
METHODS: Leaders, staff, and parents were trained in RPI concepts and tools. Multidisciplinary teams including parent members applied the training and received regular mentorship for their improvement initiatives.
RESULTS: Participants (N = 67) completed pretraining and post-training …
Kikuchi-Fujimoto Disease Complicated By Rheumatoid Arthritis, Type 1 Diabetes Mellitus, And Hypothyroidism, 2022 HCA Healthcare
Kikuchi-Fujimoto Disease Complicated By Rheumatoid Arthritis, Type 1 Diabetes Mellitus, And Hypothyroidism, Soroush Shahrokh, Ammar Hasan, Salman Raza Alim, Michelle Hebert, Khulood Rizvi
Gulf Coast Division Research Day 2022
No abstract provided.