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1,659 full-text articles. Page 6 of 65.

Lipophilic Dye-Compatible Brain Clearing Technique Allowing Correlative Magnetic Resonance/High-Resolution Fluorescence Imaging In Rat Models Of Glioblastoma, Marco Peviani, Giorgia Spano, Antonella Pagani, Gianluca Brugnara, Cesare Covino, Rossella Galli, Alessandra Biffi, Letterio S. Politi 2020 Harvard Medical School

Lipophilic Dye-Compatible Brain Clearing Technique Allowing Correlative Magnetic Resonance/High-Resolution Fluorescence Imaging In Rat Models Of Glioblastoma, Marco Peviani, Giorgia Spano, Antonella Pagani, Gianluca Brugnara, Cesare Covino, Rossella Galli, Alessandra Biffi, Letterio S. Politi

Open Access Publications by UMMS Authors

In this work we optimized a novel approach for combining in vivo MRI and ex vivo high-resolution fluorescence microscopy that involves: (i) a method for slicing rat brain tissue into sections with the same thickness and spatial orientation as in in vivo MRI, to better correlate in vivo MRI analyses with ex-vivo imaging via scanning confocal microscope and (ii) an improved clearing protocol compatible with lipophilic dyes that highlight the neurovascular network, to obtain high tissue transparency while preserving tissue staining and morphology with no significant tissue shrinkage or expansion. We applied this methodology in two rat models of glioblastoma ...


Navigating The Paradox Of Scarcity: The Case For Radiologist-Driven Care., Daniel A Ortiz, Kevin M Cregan, Join Y Luh, Taj M Kattapuram 2020 Providence St. Joseph Health, Eureka, California

Navigating The Paradox Of Scarcity: The Case For Radiologist-Driven Care., Daniel A Ortiz, Kevin M Cregan, Join Y Luh, Taj M Kattapuram

Articles, Abstracts, and Reports

No abstract provided.


Efficacy Of Beveled Tip Aspiration Catheter In Mechanical Thrombectomy For Acute Ischemic Stroke, Jan Vargas, Jonathan Blalock, Anand Venkatraman, Vania Anagnostakou, Robert M. King, Joseph A. Ewing, Matthew J. Gounis, Raymond D. Turner, Imran Chaudry, Aquilla Turk 2020 Prisma Health Upstate

Efficacy Of Beveled Tip Aspiration Catheter In Mechanical Thrombectomy For Acute Ischemic Stroke, Jan Vargas, Jonathan Blalock, Anand Venkatraman, Vania Anagnostakou, Robert M. King, Joseph A. Ewing, Matthew J. Gounis, Raymond D. Turner, Imran Chaudry, Aquilla Turk

Radiology Publications

BACKGROUND: Direct aspiration thrombectomy techniques use large bore aspiration catheters for mechanical thrombectomy. Several aspiration catheters are now available. We report a bench top exploration of a novel beveled tip catheter and our experience in treating large vessel occlusions (LVOs) using next-generation aspiration catheters.

METHODS: A retrospective analysis from a prospectively maintained database comparing the bevel shaped tip aspiration catheter versus non-beveled tip catheters was performed. Patient demographics, periprocedural metrics, and discharge and 90-day modified Rankin Scale (mRS) scores were collected. Patients were divided into two groups based on which aspiration catheter was used.

RESULTS: Our data showed no significant ...


The Many Faces Of Covid-19: Organizing Pneumonia (Op) Pattern Hrct Features, Gaetano Rea 2020 University of Salerno

The Many Faces Of Covid-19: Organizing Pneumonia (Op) Pattern Hrct Features, Gaetano Rea

Translational Medicine @ UniSa

Covid-19 (coronavirus disease 2019) is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). On 30 January 2020 the World Health Organization (WHO) declared that the outbreak of Covid-19 realizes a public health emergency of international concern. Because of the primary involvement of the respiratory system, chest CT is strongly recommended in suspected Covid-19 cases, for both initial and follow-up. We present the case of a Covid-19 patient, a 57-year-old man, with a typical HRCT course of OP reaction.


The Clinical Utilities Of Multi-Pinhole Single Photon Emission Computed Tomography, Ilker Ozsahin, Ling Chen, Arda Konik, Michael A. King, Freek J. Beekman, Greta S. P. Mok 2020 University of Macau

The Clinical Utilities Of Multi-Pinhole Single Photon Emission Computed Tomography, Ilker Ozsahin, Ling Chen, Arda Konik, Michael A. King, Freek J. Beekman, Greta S. P. Mok

Open Access Publications by UMMS Authors

Single photon emission computed tomography (SPECT) is an important imaging modality for various applications in nuclear medicine. The use of multi-pinhole (MPH) collimators can provide superior resolution-sensitivity trade-off when imaging small field-of-view compared to conventional parallel-hole and fan-beam collimators. Besides the very successful application in small animal imaging, there has been a resurgence of the use of MPH collimators for clinical cardiac and brain studies, as well as other small field-of-view applications. This article reviews the basic principles of MPH collimators and introduces currently available and proposed clinical MPH SPECT systems.


Virtual Connectivity During Quarantine: The Role Of Social Media For Radiation Oncology During Covid-19, Miriam A Knoll, Mudit Chowdhary, Adam Dicker, Thomas Eichler 2020 Montefiore Nyack Hospital

Virtual Connectivity During Quarantine: The Role Of Social Media For Radiation Oncology During Covid-19, Miriam A Knoll, Mudit Chowdhary, Adam Dicker, Thomas Eichler

Kimmel Cancer Center Faculty Papers

No abstract provided.


Integrated Multiparametric Radiomics And Informatics System For Characterizing Breast Tumor Characteristics With The Oncotypedx Gene Assay, Michael A. Jacobs, Christopher B. Umbricht, Vishwa S. Parekh, Riham H. El Khouli, Leslie Cope, Katarzyna J. Macura, Susan Harvey, Antonio C. Wolff 2020 Johns Hopkins University

Integrated Multiparametric Radiomics And Informatics System For Characterizing Breast Tumor Characteristics With The Oncotypedx Gene Assay, Michael A. Jacobs, Christopher B. Umbricht, Vishwa S. Parekh, Riham H. El Khouli, Leslie Cope, Katarzyna J. Macura, Susan Harvey, Antonio C. Wolff

Radiology Faculty Publications

Optimal use of multiparametric magnetic resonance imaging (mpMRI) can identify key MRI parameters and provide unique tissue signatures defining phenotypes of breast cancer. We have developed and implemented a new machine-learning informatic system, termed Informatics Radiomics Integration System (IRIS) that integrates clinical variables, derived from imaging and electronic medical health records (EHR) with multiparametric radiomics (mpRad) for identifying potential risk of local or systemic recurrence in breast cancer patients. We tested the model in patients (n = 80) who had Estrogen Receptor positive disease and underwent OncotypeDX gene testing, radiomic analysis, and breast mpMRI. The IRIS method was trained using the ...


Organic Field-Effect Transistors As Flexible, Tissue-Equivalent Radiation Dosimeters In Medical Applications, Andrew M. Zeidell, Tong Ren, David S. Filston, Hamna F. Iqbal, Emma Holland, J. Daniel Bourland, John E. Anthony, Oana D. Jurchescu 2020 Wake Forest University

Organic Field-Effect Transistors As Flexible, Tissue-Equivalent Radiation Dosimeters In Medical Applications, Andrew M. Zeidell, Tong Ren, David S. Filston, Hamna F. Iqbal, Emma Holland, J. Daniel Bourland, John E. Anthony, Oana D. Jurchescu

Chemistry Faculty Publications

Radiation therapy is one of the most prevalent procedures for cancer treatment, but the risks of malignancies induced by peripheral beam in healthy tissues surrounding the target is high. Therefore, being able to accurately measure the exposure dose is a critical aspect of patient care. Here a radiation detector based on an organic field‐effect transistor (RAD‐OFET) is introduced, an in vivo dosimeter that can be placed directly on a patient's skin to validate in real time the dose being delivered and ensure that for nearby regions an acceptable level of low dose is being received. This device ...


The Basics Of Neuroimaging: Techniques, Basic Anatomy And Pathology, William Pleming 2020 RAD-AID

The Basics Of Neuroimaging: Techniques, Basic Anatomy And Pathology, William Pleming

PEER Liberia Project

This presentation was part of the PEER Liberia Radiology Lecture Series. The presentation provides an overview of neuroimaging techniques including x-rays, computerised tomography, magnetic imaging, angiography, and pathology.


A Sonographer’S Step-By-Step Approach For Preventing Transmission Of Covid-19, Corinne Wessner, JoAnn Nelson, Sarah Mott, Maria Francesco, Laurence Needleman 2020 Thomas Jefferson University

A Sonographer’S Step-By-Step Approach For Preventing Transmission Of Covid-19, Corinne Wessner, Joann Nelson, Sarah Mott, Maria Francesco, Laurence Needleman

Department of Radiology Faculty Papers

The 2019 novel coronavirus, known as COVID-19, has greatly affected the way sonographers care for their patients. Sonography can be a useful imaging tool for surveillance and diagnosis of various conditions associated with COVID-19 patients or patients under investigation (PUIs). Currently, there are limited resources and protocols for preventing the transmission of COVID-19 from ultrasound equipment. Our institution has created a detailed protocol for scanning COVID-19 patients or PUIs to address this important issue.


Outcomes After Stereotactic Body Radiation Therapy As A Bridging Modality To Liver Transplantation For Hepatocellular Carcinoma, Rashi Garg, Kim Foley, Babak Movahedi, Mark Masciocchi, Jacob R. Bledsoe, Linda Ding, Paul Rava, Thomas J. Fitzgerald, Shirin Sioshansi 2020 Tufts University

Outcomes After Stereotactic Body Radiation Therapy As A Bridging Modality To Liver Transplantation For Hepatocellular Carcinoma, Rashi Garg, Kim Foley, Babak Movahedi, Mark Masciocchi, Jacob R. Bledsoe, Linda Ding, Paul Rava, Thomas J. Fitzgerald, Shirin Sioshansi

Radiology Publications

Purpose: For patients with hepatocellular carcinoma awaiting liver transplantation (LT), stereotactic body radiation therapy (SBRT) has emerged as a bridging treatment to ensure patients maintain priority status and eligibility per Milan criteria. In this study, we aimed to determine the efficacy and safety of SBRT in such situations.

Methods and Materials: A retrospective analysis was conducted of the outcomes of 27 patients treated with SBRT who were listed for LT at 1 institution. Among these, 20 patients with 26 tumors went on to LT and were the focus of this study. Operative reports and postoperative charts were evaluated for potential ...


Impact Of The Covid-19 Pandemic On Emergency Department Ct For Suspected Diverticulitis: A Natural Experiment To Explain Patients’ And Clinicians’ Assessment Of Risk And Willingness To Undergo Ct Scanning? [Preprint], Averi L. Gibson, Byron Y. Chen, Max P. Rosen, S. Nicolas Paez, Hao S. Lo 2020 University of Massachusetts Medical School

Impact Of The Covid-19 Pandemic On Emergency Department Ct For Suspected Diverticulitis: A Natural Experiment To Explain Patients’ And Clinicians’ Assessment Of Risk And Willingness To Undergo Ct Scanning? [Preprint], Averi L. Gibson, Byron Y. Chen, Max P. Rosen, S. Nicolas Paez, Hao S. Lo

COVID-19 Publications by UMMS Authors

Purpose: This study examined the impact of the COVID-19 pandemic on emergency department CT use for acute non-traumatic abdominal pain, to better understand why imaging volume so drastically decreased during the COVID-19 pandemic.

Methods: This was a retrospective review of emergency imaging volumes from January 5 to May 30, 2020. Weekly volume data were collected for total imaging studies, abdominopelvic CT, and abdominopelvic CTs positive for common causes of acute non-traumatic abdominal pain. Two emergency radiology attendings scored all diverticulitis cases independently and weekly volume data for uncomplicated and complicated diverticulitis cases was also collected. Volume data prior to and ...


Assessing Invasiveness Of Subsolid Lung Adenocarcinomas With Combined Attenuation And Geometric Feature Models, Constance de Margerie-Mellon, Ritu R. Gill, Pascal Salazar, Anastasia Oikonomou, Elsie T. Nguyen, Benedikt H. Heidinger, Mayra A. Medina, Paul A. VanderLaan, Alexander A. Bankier 2020 Harvard Medical School

Assessing Invasiveness Of Subsolid Lung Adenocarcinomas With Combined Attenuation And Geometric Feature Models, Constance De Margerie-Mellon, Ritu R. Gill, Pascal Salazar, Anastasia Oikonomou, Elsie T. Nguyen, Benedikt H. Heidinger, Mayra A. Medina, Paul A. Vanderlaan, Alexander A. Bankier

Open Access Publications by UMMS Authors

The aim of this study was to develop and test multiclass predictive models for assessing the invasiveness of individual lung adenocarcinomas presenting as subsolid nodules on computed tomography (CT). 227 lung adenocarcinomas were included: 31 atypical adenomatous hyperplasia and adenocarcinomas in situ (class H1), 64 minimally invasive adenocarcinomas (class H2) and 132 invasive adenocarcinomas (class H3). Nodules were segmented, and geometric and CT attenuation features including functional principal component analysis features (FPC1 and FPC2) were extracted. After a feature selection step, two predictive models were built with ordinal regression: Model 1 based on volume (log) (logarithm of the nodule volume ...


Localizing An Occult Insulinoma By Selective Calcium Arterial Stimulation Test: First Ever Experience And A New Dimension To Diagnosis In Pakistan, Muhammad Owais Rashid, Sumerah Jabeen, Zareen Kiran,, Khurram Minhas, Muhammad Azeemuddin, Najmul Islam 2020 The Indus Hospital, Karachi, Pakistan

Localizing An Occult Insulinoma By Selective Calcium Arterial Stimulation Test: First Ever Experience And A New Dimension To Diagnosis In Pakistan, Muhammad Owais Rashid, Sumerah Jabeen, Zareen Kiran,, Khurram Minhas, Muhammad Azeemuddin, Najmul Islam

Section of Diabetes, Endocrinology and Metabolism

Insulinomas are rare, usually benign, solitary tumours accounting for 60% of islet cell tumours. These tumours can be difficult to localize preoperatively due to their small size. We present a challenging case of a 40 year old male with frequent hypoglycaemic spells and endogenous hypoglycaemia who presented as a diagnostic dilemma. Patient had an occult insulinoma with inconclusive CT Abdomen, MRI Abdomen and Octreotide scan. The final localization of the tumour was made by selective arterial calcium stimulation testing (SCAT), done for the first time in Pakistan at Aga Khan University Hospital. This was followed by successful distal pancreatectomy as ...


Ultrasonographic Risk Stratification Of Indeterminate Thyroid Nodules; A Comparison Of An Artificial Intelligence Algorithm With Radiologist Performance, Aylin Tahmasebi, Shuo Wang, Kelly Daniels, Elizabeth Cottrill, Ji-Bin Liu, Jiajun Xu, Andrej Lyshchik, John R. Eisenbrey 2020 Thomas Jefferson University

Ultrasonographic Risk Stratification Of Indeterminate Thyroid Nodules; A Comparison Of An Artificial Intelligence Algorithm With Radiologist Performance, Aylin Tahmasebi, Shuo Wang, Kelly Daniels, Elizabeth Cottrill, Ji-Bin Liu, Jiajun Xu, Andrej Lyshchik, John R. Eisenbrey

Department of Radiology Faculty Papers

Background, Motivation and Objective: Thyroid nodules with indeterminate or suspicious cytology are commonly encountered in clinical practice and their clinical management is controversial. Recently, genetical analysis of thyroid fine needle aspiration (FNAs) was implemented at some institutions to differentiate thyroid nodules as high and low risk based on the presence of certain oncogenes commonly associated with aggressive tumor behavior and poor patient outcomes. Our group recently detailed the performance of a machine-learning model based on ultrasonography images of thyroid nodules for the prediction of high and low risk mutations. This study evaluated the performance of a second-generation machine-learning algorithm incorporating ...


Quantitative Magnetic Resonance Imaging Of Knee Articular Cartilage And Effusion-Synovitis: The Structural Response To Changes In Joint Loading, Hayden F. Atkinson 2020 The University of Western Ontario

Quantitative Magnetic Resonance Imaging Of Knee Articular Cartilage And Effusion-Synovitis: The Structural Response To Changes In Joint Loading, Hayden F. Atkinson

Electronic Thesis and Dissertation Repository

Knee osteoarthritis (OA) is a progressive degenerative condition that can affect all tissues within the joint. Methods to measure early changes in joint structures and the effect of interventions are required. The purpose of this thesis was to investigate aspects of quantitative magnetic resonance imaging (MRI) as outcome measures in knee OA studies. Specifically, changes in articular cartilage composition and/or effusion-synovitis were examined in people with or at risk for knee OA and healthy controls, and after altering joint loads.

Chapter 2 is a systematic review that studied articular cartilage composition using MRI T2 and T1ρ relaxation in patients ...


Detection Of Left Ventricular Thrombi On Cardiac Magnetic Resonance Viability Studies, Donya Ahmed Alhassan, Khawaja Bilal Waheed, Muhammad Nasim Sharif, Muhammad Zia UlHassan, Fazal Ghaffar, Khaled Saleh Saleem, Emad Fouad Mahmoud Said, Bayan Mohammed Altalaq, Zechariah Jebakumar Arulanantham, Ahmad Omar Qarmash 2020 King Fahad Military Medical Complex

Detection Of Left Ventricular Thrombi On Cardiac Magnetic Resonance Viability Studies, Donya Ahmed Alhassan, Khawaja Bilal Waheed, Muhammad Nasim Sharif, Muhammad Zia Ulhassan, Fazal Ghaffar, Khaled Saleh Saleem, Emad Fouad Mahmoud Said, Bayan Mohammed Altalaq, Zechariah Jebakumar Arulanantham, Ahmad Omar Qarmash

Journal of the Saudi Heart Association

Objective: To highlight detection of left ventricular thrombi on cardiac magnetic resonance (CMR) viability studies.

Method: This retrospective observational study was conducted in the Radiology Department at our Hospital in Dhahran, from April 2015-2019. All recently re-perfused (post-percutaneous coronary intervention/ PCI) patients with ST-segment elevation myocardial infarctions (STEMI), having low ejection fractions (

Results: Of the 125 patients, most were men (71.2%) with a mean age of 56.78 years. Eleven patients had left ventricular thrombi (8.8%), and most of these were anterior wall infarctions with low ejection fractions (

Conclusion: Left ventricular thrombi can be detected on cardiac viability ...


Digital Breast Tomosynthesis Versus Additional Diagnostic Mammographic Views For The Evaluation Of Asymmetric Mammographic Densities, Hira Waheed, Imrana Masroor, Shaista Afzal Saeed, Muhammad Ismail Alvi, Syed Jahanzeb 2020 Aga Khan University

Digital Breast Tomosynthesis Versus Additional Diagnostic Mammographic Views For The Evaluation Of Asymmetric Mammographic Densities, Hira Waheed, Imrana Masroor, Shaista Afzal Saeed, Muhammad Ismail Alvi, Syed Jahanzeb

Department of Radiology

Introduction: Many young females present with an advanced stage of breast cancer, which has a negative effect on the prognosis. Digital breast tomosynthesis is a new emerging imaging technique that aids in improving the specificity of mammography with subsequent early detection of breast cancer, especially in women with radiographically dense breasts. Tomosynthesis is subjectively preferred to conventional mammography and may offer superior diagnostic accuracy for the evaluation of breast lesions.
Method: Two breast radiologists retrospectively reviewed asymmetric densities using protocols that were institutional review board-approved in 185 patients aged 18 - 70 years (mean: 48 years) who underwent diagnostic mammography and ...


Contemporary Interventional Radiology Employment: Analysis Of The American College Of Radiology And The Society Of Interventional Radiology Occupational Portals, Anthony N Hage, Vibhor Wadhwa, Eric J Monroe, David S Shin, Jeffrey Forris Beecham Chick 2020 Thomas Jefferson University

Contemporary Interventional Radiology Employment: Analysis Of The American College Of Radiology And The Society Of Interventional Radiology Occupational Portals, Anthony N Hage, Vibhor Wadhwa, Eric J Monroe, David S Shin, Jeffrey Forris Beecham Chick

Department of Radiology Faculty Papers

No abstract provided.


Investigation Of Axial And Angular Sampling In Multi-Detector Pinhole-Spect Brain Imaging, Navid Zeraatkar, Kesava S. Kalluri, Benjamin Auer, Arda Konik, Timothy J. Fromme, Lars R. Furenlid, Phillip H. Kuo, Michael A. King 2020 University of Massachusetts Medical School

Investigation Of Axial And Angular Sampling In Multi-Detector Pinhole-Spect Brain Imaging, Navid Zeraatkar, Kesava S. Kalluri, Benjamin Auer, Arda Konik, Timothy J. Fromme, Lars R. Furenlid, Phillip H. Kuo, Michael A. King

Radiology Publications

We designed a dedicated multi-detector multi-pinhole brain SPECT scanner to generate images of higher quality compared to general-purpose systems. The system, AdaptiSPECT-C, is intended to adapt its sensitivity-resolution trade-off by varying its aperture configurations allowing both high-sensitivity dynamic and high-spatial-resolution static imaging. The current system design consists of 23 detector heads arranged in a truncated spherical geometry. In this work, we investigated the axial and angular sampling capability of the current stationary system design. Two data acquisition schemes using limited rotation of the gantry and two others using axial translation of the imaging bed were also evaluated concerning their impact ...


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