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Experience With An Ultrasound Donation Program In A Low-Income Country, Michelle Hershman, Melody Hershman, Yamile Blain, Marie Evelyne Moise, Natasha Monchil, Amy A. Walters, Berndt P. Schmit 2021 Hospital of the University of Pennsylvania

Experience With An Ultrasound Donation Program In A Low-Income Country, Michelle Hershman, Melody Hershman, Yamile Blain, Marie Evelyne Moise, Natasha Monchil, Amy A. Walters, Berndt P. Schmit

Journal of Global Radiology

Increasing radiology capacity in low-income countries (LIC) can improve clinicians’ access to diagnostic imaging tools and improve patient care. Ultrasound (US) is important in LIC due to its lower cost compared to that of CT or MRI scans and its excellent diagnostic ability. The relative portability of the equipment makes it ideal for donation by charitable organizations. We describe our experience as a radiology-capacity-focused charity working with the Haitian healthcare system and propose strategies to increase ultrasound capacity in other poor countries.


Radiopharmaceutical Validation For Clinical Use, Charles A. Kunos, Rodney Howells, Aman Chauhan, Zin W. Myint, Mark E. Bernard, Riham H. El Khouli, Jacek Capala 2021 National Cancer Institute

Radiopharmaceutical Validation For Clinical Use, Charles A. Kunos, Rodney Howells, Aman Chauhan, Zin W. Myint, Mark E. Bernard, Riham H. El Khouli, Jacek Capala

Internal Medicine Faculty Publications

Radiopharmaceuticals are reemerging as attractive anticancer agents, but there are no universally adopted guidelines or standardized procedures for evaluating agent validity before early-phase trial implementation. To validate a radiopharmaceutical, it is desirous for the radiopharmaceutical to be specific, selective, and deliverable against tumors of a given, molecularly defined cancer for which it is intended to treat. In this article, we discuss four levels of evidence—target antigen immunohistochemistry, in vitro and in vivo preclinical experiments, animal biodistribution and dosimetry studies, and first-in-human microdose biodistribution studies—that might be used to justify oncology therapeutic radiopharmaceuticals in a drug-development sequence involving early-phase ...


Morel-Lavallée Lesion In A 35-Year Female, Amir Humza Sohail, Muhammad Talha Liaquat, Mohammed Sachal Sohail, Muhammad Salman Khan, Hazim Hakmi 2021 NYU Langone Hospital Long Island, New York, USA.

Morel-Lavallée Lesion In A 35-Year Female, Amir Humza Sohail, Muhammad Talha Liaquat, Mohammed Sachal Sohail, Muhammad Salman Khan, Hazim Hakmi

Department of Radiology

Morel-Lavallée lesion is a post-traumatic degloving cyst, usually filled with blood, lymph or necrotic tissue, which mostly develops in the area around greater trochanter. Early diagnosis and prompt treatment is essential to prevent further complications, such as compression of surrounding structures. X-rays have limited use and magnetic resonance imaging (MRI) is the modality of choice in diagnosing the lesion. We report a case of a 35-year female presenting with left thigh pain after a fall from motorcycle almost 21/2 years ago. Ultrasound and MRI confirmed the presence of Morel-Lavallée lesion involving the left pelvis and upper thigh. Given the ...


Angioembolisation For The Treatment Of Pseudo-Aneurysm Of Internal Maxillary Artery, Muhammad Azeemuddin, Anosha Khan, Atif Hafeez Siddiqui, Asad Shakil, Basit Salam, Raza Sayani 2021 Aga Khan University

Angioembolisation For The Treatment Of Pseudo-Aneurysm Of Internal Maxillary Artery, Muhammad Azeemuddin, Anosha Khan, Atif Hafeez Siddiqui, Asad Shakil, Basit Salam, Raza Sayani

Department of Radiology

Pseudo-aneurysm of internal maxillary artery, following a road traffic accident, is a rare clinical scenario. The consequence of pseudo-aneurysm may be spontaneous rupture of the arterial wall, which may eventually lead to life-threatening hemorrhage. We report a case of a 20-year male who presented with recurrent epistaxis. CT scan was performed, which revealed a pseudo-aneurysm of the internal maxillary artery; this was successfully treated by angioembolisation. Similar cases of traumatic pseudo-aneurysms have been reported, however, none presented with recurrent epistaxis after management of pan-facial fractures. Key Words: Epistaxis, Pseudo-aneurysm, Angioembolisation, Pan-facial fracture.


Image Guided Central Venous Catheter Placement, Nurullah Dogan, Mustafa Gok, Demet Gunduz 2021 Doruk Medical Center, Bursa, Turkey

Image Guided Central Venous Catheter Placement, Nurullah Dogan, Mustafa Gok, Demet Gunduz

Health Sciences

Nowadays, central venous catheters (CVCs) are widely used medical tools for patients with chronic diseases or patients following in intensive care units (ICU), both for treatment and follow-up (drugs, fluids, blood and blood products, hemodynamic monitoring, etc.). With new drugs and treatment methods, demand for CVCs is increasing accordingly. While it was applied with landmark technique by only surgical departments for many years, it has been used by interventional radiologists under the guidance of imaging methods since 1990s. Due to the low rates of perioperative and early complications and the short duration of the procedure, imaging-guided CVC implantation has been ...


Ultrasound Of Superficial Lumps And Bumps, Robert D. Harris 2021 RAD-AID

Ultrasound Of Superficial Lumps And Bumps, Robert D. Harris

PEER Liberia Project

This presentation is part of the PEER Liberia Radiology Lecture Series. It provides an overview for clinicians about the diagnosis and ultrasound of lumps, bumps and other soft tissue lesions in the skin.


Duration Of Rheumatoid Arthritis And The Risk Of Developing Interstitial Lung Disease, Michael P. Mohning, Isabelle Amigues, M. Kristen Demoruelle, Evans R. Fernández Pérez, Tristan J. Huie, Rebecca K. Keith, Amy L. Olson, Zulma X. Yunt, Jonathan H. Chung, Stephen B. Hobbs, Jeffrey J. Swigris, Joshua J. Solomon 2021 National Jewish Health

Duration Of Rheumatoid Arthritis And The Risk Of Developing Interstitial Lung Disease, Michael P. Mohning, Isabelle Amigues, M. Kristen Demoruelle, Evans R. Fernández Pérez, Tristan J. Huie, Rebecca K. Keith, Amy L. Olson, Zulma X. Yunt, Jonathan H. Chung, Stephen B. Hobbs, Jeffrey J. Swigris, Joshua J. Solomon

Radiology Faculty Publications

Age of ILD onset is similar in patients with RA-UIP and RA-NSIP but duration of RA before ILD onset differs.


A Concise Review Of The Multimodality Imaging Features Of Renal Cell Carcinoma, Ali Morshid, Elif S. Duran, Woongsoon J. Choi, Cihan Duran 2021 The University of Texas Rio Grande Valley

A Concise Review Of The Multimodality Imaging Features Of Renal Cell Carcinoma, Ali Morshid, Elif S. Duran, Woongsoon J. Choi, Cihan Duran

School of Medicine Publications and Presentations

The evaluation of renal cell carcinoma (RCC) is routinely performed using the multimodality imaging approach, including ultrasonography, computed tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography (PET). Ultrasonography is the most frequently used imaging modality for the initial diagnosis of renal masses. The modality of choice for the characterization of the renal mass is multiphasic CT. Recent advances in CT technology have led to its widespread use as a powerful tool for preoperative planning, reducing the need for catheter angiography for the evaluation of vascular invasion. CT is also the standard imaging modality for staging and follow-up. MRI ...


Evaluation Of Radiology Request Forms In A Tertiary Care Hospital: An Audit With A Focus On The Impact Of Technological Intervention, Muhammad Danish Barakzai, Zara Za Sheer, Muhammad Azeemuddin, Amna Alvi, Nouman Khan, Waseem M. Nizamani, Madiha Beg, Saad Siddiqui 2021 Children's Hospital of Eastern Ontario, Ontario, CAN.

Evaluation Of Radiology Request Forms In A Tertiary Care Hospital: An Audit With A Focus On The Impact Of Technological Intervention, Muhammad Danish Barakzai, Zara Za Sheer, Muhammad Azeemuddin, Amna Alvi, Nouman Khan, Waseem M. Nizamani, Madiha Beg, Saad Siddiqui

Community Health Sciences

Radiology request forms are the basis of communication between referring physicians and radiologists. These are the sole documents on the basis of which a justification to carry out a radiological procedure is carried out. However, across the globe, there is a problem of inadequately filled radiology request forms. Several interventions like standardization and the use of technology have been proposed worldwide to overcome the shortcomings of inadequately filled radiology request forms. We carried out a two-phase audit assessing the impact of a technological intervention on the quality of radiology requests with the results showing marked improvement in key parameters. A ...


Contrast-Enhanced Endoscopic Ultrasound For Identification Of Sentinel Lymph Nodes In Esophageal Cancer, Bethanne Venkatesan, Ji-Bin Liu, MD, John R. Eisenbrey, PhD, Sriharsha Gummadi, MD, Thomas Kowalski, MD, Robert Coben, MD, Flemming Forsberg, PhD, Corinne Wessner, Priscilla Machado, MD, David Loren, MD 2021 Thomas Jefferson University

Contrast-Enhanced Endoscopic Ultrasound For Identification Of Sentinel Lymph Nodes In Esophageal Cancer, Bethanne Venkatesan, Ji-Bin Liu, Md, John R. Eisenbrey, Phd, Sriharsha Gummadi, Md, Thomas Kowalski, Md, Robert Coben, Md, Flemming Forsberg, Phd, Corinne Wessner, Priscilla Machado, Md, David Loren, Md

Phase 1

Introduction:

In esophageal carcinoma, lymph node involvement is a crucial aspect of nodal staging and determining treatment strategies. Although grayscale endoscopic ultrasound (EUS) is the standard of care for staging, it is unable to identify lymph node drainage from primary tumors or sentinel lymph nodes (SLN). The goal of this study was to determine if Contrast Enhanced Endoscopic Ultrasound (CE- EUS) is superior to EUS in the identification of SLNs and nodal staging in esophageal carcinoma.

Methods:

In the unblinded pilot study, patients with newly diagnosed esophageal carcinoma were recruited to undergo CE-EUS and standard EUS. EUS was performed and ...


Radiation‐Induced Oral Mucositis Hamster Model Using A Linear Accelerator Enhances Clinical Relevance Of Preclinical Studies For Treatment Strategy Investigation, Carolyn T. Jordan, Emily M. Bradford, Dennis C. Cheek, Mahesh R. Kudrimoti, Craig S. Miller, Molly H. Smith, J. Zach Hilt, Thomas D. Dziubla 2021 University of Kentucky

Radiation‐Induced Oral Mucositis Hamster Model Using A Linear Accelerator Enhances Clinical Relevance Of Preclinical Studies For Treatment Strategy Investigation, Carolyn T. Jordan, Emily M. Bradford, Dennis C. Cheek, Mahesh R. Kudrimoti, Craig S. Miller, Molly H. Smith, J. Zach Hilt, Thomas D. Dziubla

Radiation Medicine Faculty Publications

Translational animal models for oral mucositis (OM) are necessary to simulate and assess the bioclinical effects and response in humans. These models should simulate high levels of radiation exposure that leads to oxidative stress and inflammatory‐initiated tissue changes. Hamster models have been extensively studied to observe pathological effects of radiation exposure and help in the development of effective treatments. To successfully evaluate the potential for treatment regimens with consistency and relevance, a radiation‐induced OM hamster model was developed using a clinical linear accelerator utilized by cancer patients daily. The dose exposure to the isolated, everted cheek pouch of ...


The State Of Interventional Radiology In Myanmar: A National Report, Benjamin Jyhhan Kuo, Myo Oo Aung, Ngwe Phyu Hnin, Taryi Wint, Tin Htun Aung, Kyaw Zay Ya, Bien Soo Tan 2021 Singapore General Hospital

The State Of Interventional Radiology In Myanmar: A National Report, Benjamin Jyhhan Kuo, Myo Oo Aung, Ngwe Phyu Hnin, Taryi Wint, Tin Htun Aung, Kyaw Zay Ya, Bien Soo Tan

Journal of Global Radiology

Purpose: Radiology global outreach programs have increased in recent years but progressed more slowly than other specialties. Establishing radiology services is increasingly recognized as a priority in resource-limited settings. Myanmar has a tremendous disease burden that is treatable with interventional radiology (IR) techniques, and aims to grow and effectively integrate this service into its public healthcare sector. Through collaborations between Asia Pacific Society of Cardiovascular and Interventional Radiology (APSCVIR) and Myanmar Radiological Society (MRS), the field of IR has grown exponentially over recent years. This study aims to provide a Myanmar national IR report on the current trends and future ...


Improved Image Reconstruction Of, Julian Kirchner, Joseph A O'Donoghue, Anton S Becker, Gary A Ulaner 2021 Molecular Imaging and Therapy, Hoag Family Cancer Institute, Newport Beach, CA, USA.

Improved Image Reconstruction Of, Julian Kirchner, Joseph A O'Donoghue, Anton S Becker, Gary A Ulaner

Articles, Abstracts, and Reports

Purpose: The aim of this study was to evaluate the use of a Bayesian penalized likelihood reconstruction algorithm (Q.Clear) for 89Zr-immunoPET image reconstruction and its potential to improve image quality and reduce the administered activity of 89Zr-immunoPET tracers.

Methods: Eight 89Zr-immunoPET whole-body PET/CT scans from three 89Zr-immunoPET clinical trials were selected for analysis. On average, patients were imaged 6.3 days (range 5.0-8.0 days) after administration of 69 MBq (range 65-76 MBq) of [89Zr]Zr-DFO-daratumumab, [89Zr]Zr-DFO-pertuzumab, or [89Zr]Zr-DFO-trastuzumab. List-mode PET data was retrospectively reconstructed using Q.Clear with incremental β-values from 150 to 7200 ...


A Multidisciplinary Approach To Triage Patients With Breast Disease During The Covid-19 Pandemic: Experience From A Tertiary Care Center In The Developing World, Abida K. Sattar, Hania Shahzad, Adnan Abdul Jabbar, Azmina Tajdin Valimohammad, Sadaf Khan, Yasmin Vellani, Romana Idrees, Nasir Ali, Imrana Masroor, Humera Saeed, Gulzar S. Lakhani, Nadia Ayoub, Atif Waqar, Muhammad Zia-Ul Islam, Salman Kirmani, Asad Latif, Syed Ather Enam 2021 Aga Khan University

A Multidisciplinary Approach To Triage Patients With Breast Disease During The Covid-19 Pandemic: Experience From A Tertiary Care Center In The Developing World, Abida K. Sattar, Hania Shahzad, Adnan Abdul Jabbar, Azmina Tajdin Valimohammad, Sadaf Khan, Yasmin Vellani, Romana Idrees, Nasir Ali, Imrana Masroor, Humera Saeed, Gulzar S. Lakhani, Nadia Ayoub, Atif Waqar, Muhammad Zia-Ul Islam, Salman Kirmani, Asad Latif, Syed Ather Enam

Section of General Surgery

Background: The COVID-19 pandemic has created a need to prioritize care because of limitation of resources. Owing to the heterogeneity and high prevalence of breast cancers, the need to prioritize care in this vulnerable population is essential. While various medical societies have published recommendations to manage breast disease during the COVID-19 pandemic, most are focused on the Western world and do not necessarily address the challenges of a resource-limited setting.
Aim: In this article, we describe our institutional approach for prioritizing care for patients presenting with breast disease.
Methods and results: The breast disease management guidelines were developed and approved ...


Basics Of Renal Ultrasound, Robert D. Harris 2021 RAD-AID

Basics Of Renal Ultrasound, Robert D. Harris

PEER Liberia Project

This presentation is part of the PEER Liberia Radiology Lecture Series. This presentation provides an overview of the basics of renal ultrasound.


The Association Of Chest Radiographic Findings And Severity Scoring With Clinical Outcomes In Patients With Covid-19 Presenting To The Emergency Department Of A Tertiary Care Hospital In Pakistan, Raima Kaleemi, Kiran Hilal, Ainan Arshad, Russell Seth Martins, Avinash Nankani, Tanveer Ul Haq, Sundas Basharat, Zeeshan Ansar 2021 Aga Khan University

The Association Of Chest Radiographic Findings And Severity Scoring With Clinical Outcomes In Patients With Covid-19 Presenting To The Emergency Department Of A Tertiary Care Hospital In Pakistan, Raima Kaleemi, Kiran Hilal, Ainan Arshad, Russell Seth Martins, Avinash Nankani, Tanveer Ul Haq, Sundas Basharat, Zeeshan Ansar

Department of Radiology

Introduction: While chest x-rays (CXRs) represent a cost-effective imaging modality for developing countries like Pakistan, their utility for the prognostication of COVID-19 has been minimally explored. Thus, we describe the frequency and distribution of CXR findings, and their association with clinical outcomes of patients with COVID-19.
Methods: All adult (≥ 18 years) patients presenting between 28th February-31st May to the emergency department of a tertiary care hospital in Pakistan, who were COVID-19 positive on RT-PCR with CXR done on presentation, were included. A CXR Severity Score (CXR-SS) of 0-8 was used to quantify the extent of pulmonary infection on CXR, with ...


Connected: Using A Novel In-House Communication System To Efficiently Deliver Imaging Results, Daniel Greentree, Brendan R. Calhoun, Steven Farraher 2021 Maine Medical Center

Connected: Using A Novel In-House Communication System To Efficiently Deliver Imaging Results, Daniel Greentree, Brendan R. Calhoun, Steven Farraher

Journal of Maine Medical Center

Introduction: The primary objective was to investigate the effectiveness of a fully staffed electronic communication system (1Connect) in delivering timely critical imaging results and incidental findings. The secondary objective was to evaluate the financial impact of this system on a radiology practice.

Methods: From January 2014 through June 2016, the 1Connect database was retrospectively reviewed and sorted by category of submission type: Critical (1-hour communication time), STAT (2 hours), or Unexpected finding (3 business days). The percent of successful communications completed within the appropriate time frame was calculated for each priority category and used as a measure of the system ...


Cerrahi Tıp Bilimleri Tanı Ve Tedavi, Tolga Önder, Serhat Doğan, Yusuf Aydın, Ferhat Çay, Aytül Hande Yardımcı, Nazan Çevik 2021 Istanbul Taksim Training and Research Hospital

Cerrahi Tıp Bilimleri Tanı Ve Tedavi, Tolga Önder, Serhat Doğan, Yusuf Aydın, Ferhat Çay, Aytül Hande Yardımcı, Nazan Çevik

Health Sciences

Cerrahinin tarihinin insanlık kadar eski olduğu bilinse de en net belge Antik Yunan Dönemi’nde yaşamış olan Hipokrat’ın yazdığı ‘On The Surgery’ yani ‘Cerrahide’ (MÖ 400) kitabıdır. Bu kitapta cerrahlar karşımıza uzman olarak çıkmakta ve cerrahların yapması gerekenler, asistanları, cerrahi el aletleri ve travmalara yaklaşımlara kadar pek çok konudan bahsedilmektedir


To Determine The Efficacy Of Bilateral Inferior Petrosal Sinus Sampling In Differentiating Cushing Disease From Ectopic Cushing Syndrome, Muhammad Azeemuddin, Tanveer Ul Haq, Shahmeer Khan, Raza Sayani, Ayesha Shoukat Hussain, Rumaisa Khan 2021 Aga Khan University

To Determine The Efficacy Of Bilateral Inferior Petrosal Sinus Sampling In Differentiating Cushing Disease From Ectopic Cushing Syndrome, Muhammad Azeemuddin, Tanveer Ul Haq, Shahmeer Khan, Raza Sayani, Ayesha Shoukat Hussain, Rumaisa Khan

Department of Radiology

Management of endogenous Cushing syndrome is based on its aetiology. Increased Adrenocorticotropic Hormone (ACTH) levels are the most common cause of this disorder and, therefore, it is critical to determine the source of ACTH before further management. Dynamic post contrast MRI is currently the most common investigation implied to diagnose pituitary adenoma; however, it comes with the drawback of low specificity and high false positive results. Inferior petrosal sinus sampling (IPSS) is an established invasive procedure performed to differentiate central versus peripheral source of ACTH which, in turn, results in hypercortesolaemia. This is a series of 14 patients who underwent ...


Role Of Preoperative Embolization In Management Of Central Nervous System Tumours, Ummey Hani, Ahmer Nasir Baig, Muhammad Shahzad Shamim, Basit Salam 2021 Aga Khan University

Role Of Preoperative Embolization In Management Of Central Nervous System Tumours, Ummey Hani, Ahmer Nasir Baig, Muhammad Shahzad Shamim, Basit Salam

Section of Neurosurgery

Preoperative embolization plays a significant role as an adjunct to surgical intervention in the cases of certain vascular tumours of the brain. While the procedure has resulted in facilitated resection of the tumour, and has reduced morbidity and mortality, its application remains debatable within the neurosurgical community, owing to rare, but major post-procedural complications. Herein, we have reviewed the literature to assess the safety and efficacy of preoperative angiographic embolization for brain tumours.


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