James Madison University
Yale University
Cluj Napoca University of Medicine and Pharmacy, Cluj Napoca, Romania
Saint Louis University School of Law
The George Washington University Milken Institute School of Public Health
Livre de Lyon
Northwell Health
1Legacy Medical Group, Portland, OR, USA
Covid-19 Newsletter (Vol. 71),
2021
Touro College and University System
Covid-19 Newsletter (Vol. 71), Center For Disaster Medicine, New York Medical College
COVID-19 Newsletter
No abstract provided.
Covid-19 Newsletter (Vol. 70),
2021
Touro College and University System
Covid-19 Newsletter (Vol. 70), Center For Disaster Medicine, New York Medical College
COVID-19 Newsletter
No abstract provided.
Thyreos Completes Seed Funding From Invest Nebraska, Strategic Angel Investors,
2021
University of Nebraska - Lincoln
Thyreos Completes Seed Funding From Invest Nebraska, Strategic Angel Investors, Nebraska Combine
The Combine
First paragraph:
Thyreos (https://www.thyreosvaccines.com/), a vaccine company that is developing a novel vaccine platform that protects against a range of herpesviruses, has announced a $750,000 investment round led by Invest Nebraska with participation from other local angel investors in the animal health and veterinary space.
The Clinical Review Committee: Impact Of The Development Of In Vitro Diagnostic Tests For Sars-Cov-2 Within Radx Tech,
2021
Johns Hopkins University
The Clinical Review Committee: Impact Of The Development Of In Vitro Diagnostic Tests For Sars-Cov-2 Within Radx Tech, Matthew L. Robinson, Laura L. Gibson, David D. Mcmanus
Open Access Publications by UMMS Authors
The NIH Rapid Acceleration of Diagnostics (RADx SM ) Tech Program was created to speed the development, validation, and commercialization of innovative point-of-care (POC) and home-based tests, and to improve clinical laboratory tests, that can directly detect SARS-CoV-2. Leveraging the experience of the Point-of-Care Technologies Research Network, a Clinical Review Committee (CRC) composed of clinicians, bioengineers, regulatory experts, and laboratorians was created to provide structured feedback to SARS-CoV-2 diagnostic innovators. The CRC convened 53 meetings with 49 companies offering SARS-CoV-2 tests in POC and reference laboratory formats as well as collection materials. The CRC identified common barriers to device design finalization ...
The Radx Tech Clinical Studies Core: A Model For Academic Based Clinical Studies,
2021
University of Massachusetts Medical School
The Radx Tech Clinical Studies Core: A Model For Academic Based Clinical Studies, Laura L. Gibson, Nisha M. Fahey, Nathaniel Hafer, John P. Broach, Bruce A. Barton, Stephenie C. Lemon, Allison Blodgett, David D. Mcmanus
Open Access Publications by UMMS Authors
The National Institutes of Health (NIH) launched the Rapid Acceleration of Diagnostics (RADx SM ) Tech initiative to support the development and commercialization of novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) point-of-care test devices. The primary objective of the Clinical Studies Core (CSC) was to perform SARS-CoV-2 device studies involving diverse populations and settings. Within a few months, the infrastructure for clinical studies was developed, including a master protocol, digital study platform, data management system, single IRB, and multi-site partnerships. Data from some studies are being used to support Emergency Use Authorization of novel SARS-CoV-2 test devices. The CSC reduced ...
The Radx Tech Test Verification Core And The Acme Poct In The Evaluation Of Covid-19 Testing Devices: A Model For Progress And Change,
2021
Emory University
The Radx Tech Test Verification Core And The Acme Poct In The Evaluation Of Covid-19 Testing Devices: A Model For Progress And Change, Eric J. Nehl, Karl J. Simin, Nathaniel Hafer, David D. Mcmanus
Open Access Publications by UMMS Authors
Faced with the COVID-19 pandemic, the US system for developing and testing technologies was challenged in unparalleled ways. This article describes the multi-institutional, transdisciplinary team of the “RADx SM Tech Test Verification Core” and its role in expediting evaluations of COVID-19 testing devices. Expertise related to aspects of diagnostic testing was coordinated to evaluate testing devices with the goal of significantly expanding the ability to mass screen Americans to preserve lives and facilitate the safe return to work and school. Focal points included: laboratory and clinical device evaluation of the limit of viral detection, sensitivity, and specificity of devices in ...
Hypertension As A Sequela In Patients Of Sars-Cov-2 Infection.,
2021
Department of Cardiology & Cardiovascular Research Institute, Renmin Hospital of Wuhan University, Wuhan, China
Hypertension As A Sequela In Patients Of Sars-Cov-2 Infection., Ganxiao Chen, Xun Li, Zuojiong Gong, Hao Xia, Yao Wang, Xuefen Wang, Yan Huang, Hector Barajas-Martinez, Dan Hu
Department of Medicine Faculty Papers
BACKGROUND: COVID-19 is a respiratory infectious disease caused by SARS-CoV-2, and cardiovascular damage is commonly observed in affected patients. We sought to investigate the effect of SARS-CoV-2 infection on cardiac injury and hypertension during the current coronavirus pandemic.
STUDY DESIGN AND METHODS: The clinical data of 366 hospitalized COVID-19-confirmed patients were analyzed. The clinical signs and laboratory findings were extracted from electronic medical records. Two independent, experienced clinicians reviewed and analyzed the data.
RESULTS: Cardiac injury was found in 11.19% (30/268) of enrolled patients. 93.33% (28/30) of cardiac injury cases were in the severe group. The ...
Covid-19 Newsletter (Vol. 69),
2021
Touro College and University System
Covid-19 Newsletter (Vol. 69), Center For Disaster Medicine, New York Medical College
COVID-19 Newsletter
No abstract provided.
Streptococcus Anginosus Lung Infection And Empyema: A Case Report And Review Of The Literature,
2021
University of Louisville
Streptococcus Anginosus Lung Infection And Empyema: A Case Report And Review Of The Literature, Nishita Tripathi, Kuldeep Ghosh, Anupama Raghuram
The University of Louisville Journal of Respiratory Infections
Streptococcus milleri group (SMG) also referred to as the Streptococcus anginosus group. These are Gram-positive, variable hemolysis, catalase negative, microaerophilic, non-motile facultative anaerobes which have been known to cause abscesses in humans. We report a case of empyema caused by Streptococcus anginosus in a patient with an unresolved pneumonia for over a month. In early October 2018, the patient presented to an emergency room with the complaints of shortness of air, productive cough, chills, subjective fever and weight loss for 4 weeks. A chest X-ray revealed a left lower lobe pneumonia. He was treated with 250 mg of azithromycin for ...
Neurosurgical Praxis Guidelines During The Covid-19 Outbreak. Consensus-Based On Currently Available Literature.,
2021
The American British Cowdray Medical Center IAP
Neurosurgical Praxis Guidelines During The Covid-19 Outbreak. Consensus-Based On Currently Available Literature., José Antonio Soriano Sánchez, Bárbara Nettel Rueda, José Alberto Israel Romero Rangel, Armando Alpizar Aguirre, Miguel Ángel Andrade-Ramos, Ulises García Dr., Diego Mendez Rosito, Jorge A. Santos, Sara Patricia Pérez Reyes, Julian Eduardo Soto Abraham, Jose E. Valerio Pascua, Marco Antonio Barajas Romero, Eduardo Díaz Juárez, Alma Griselda Ramírez Reyes, Maria Elena Gonzalez, Claudia Katiutska González Valdez, Félix Domínguez Cortinas, Noé Santiago Ramírez, Tenoch Herrada Pineda, Manuel Eduardo Soto García, Edgar Nathal Vera, Gustavo Melo Guzmán
Archives of Neurosurgery
INTRODUCTION: The World Health Organization recommended several strategies to contain the COVID-19 pandemic, including optimization of care for all patients, especially the seriously ill. Given the strain, the pandemic has posed on healthcare systems around the world, many neurosurgical associations have provided triage recommendations for patients to save resources for the pandemic. We aimed to provide practical recommendations based on specific illnesses requiring surgical procedures commonly performed by neurosurgeons on a life-threatening basis of patient illness. We consider this guideline will help neurosurgeons for the appropriate triage of patients on a daily-situation basis during this pandemic.
METHODS: The Mexican Society ...
Hiv-1 Drug Resistance To Integrase Strand Transfer Inhibitors In Hiv-1 Non-B Subtypes,
2021
The University of Western Ontario
Hiv-1 Drug Resistance To Integrase Strand Transfer Inhibitors In Hiv-1 Non-B Subtypes, Emmanuel Ndashimye
Electronic Thesis and Dissertation Repository
Human immunodeficiency syndrome (HIV-1) has infected over 75 million people and over 35 million have succumbed to virus related illnesses. Despite access to a variety of antiretroviral therapy (ART) options, ART programs have been disproportionally spread in the world with low-and middle-income countries (LMICs) facing challenges to access the most potent ART options. With less potent ART remaining in use in LMICs, HIV-1 drug resistance (HIVDR) presents a growing challenge in LMICs. Since approval of the first-generation integrase strand transfer inhibitor (INSTIs), Raltegravir (RAL) in 2007, INSTIs remain the best choice as a backbone of ART. Access to second generation ...
Covid-19 Newsletter (Vol. 68),
2021
Touro College and University System
Covid-19 Newsletter (Vol. 68), Center For Disaster Medicine, New York Medical College
COVID-19 Newsletter
No abstract provided.
Preprocedure Covid-19 Testing In Early Phase Of Pandemic,
2021
Aurora Cardiovascular and Thoracic Services, Aurora Sinai/Aurora St. Luke’s Medical Centers
Preprocedure Covid-19 Testing In Early Phase Of Pandemic, Renuka Jain, Bradley Kruger, Robert Citronberg, Stacie Kroboth, Ana Cristina Perez Moreno, Bijoy K. Khandheria
Journal of Patient-Centered Research and Reviews
The COVID-19 pandemic led to a nationwide shutdown of elective medical procedures. Upon resumption of services, preprocedure nasopharyngeal swab testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was introduced for all patients requiring surgical or other aerosol-generating procedures. We investigated preprocedure COVID-19 testing in one of the largest U.S. health systems. Patients included in this retrospective, observational study were asymptomatic and scheduled for a procedure or surgery. All patients underwent a nasopharyngeal swab test for SARS-CoV-2 performed 24–72 hours prior to a planned procedure. Clinical demographics, type of procedure, test results, and subsequent procedure status were evaluated ...
Seroprevalence Of Sars-Cov-2 Antibody In Echocardiography And Stress Laboratory,
2021
Advocate Aurora Health
Seroprevalence Of Sars-Cov-2 Antibody In Echocardiography And Stress Laboratory, Renuka Jain, Stacie Kroboth, Denise Ignatowski, Bijoy K. Khandheria
Journal of Patient-Centered Research and Reviews
Purpose: Transesophageal echocardiography is an aerosol-generating procedure, and exercise stress testing is a potentially aerosol-generating activity. Concern has been raised about heightened risk of transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among health care personnel participating in these procedures. We aimed to investigate the prevalence of past coronavirus disease 2019 (COVID-19) infection in echocardiography and stress laboratory staff.
Methods: All staff who worked in the echocardiography and stress laboratories of one high-traffic urban hospital from March 15, 2020, to June 15, 2020, were asked to voluntarily participate. Those willing to participate were consented, and past COVID-19 infection was ...
Covid-19 Newsletter (Vol. 67),
2021
Touro College and University System
Covid-19 Newsletter (Vol. 67), Center For Disaster Medicine, New York Medical College
COVID-19 Newsletter
No abstract provided.
D-Dimer Levels And Acute Pulmonary Embolism Development In Covid-19 Patients,
2021
DEPARTMENT OF RADIOLOGY, UNIVERSITY OF HEALTH SCIENCE FATIH SULTAN MEHMET TRAINING AND RESEARCH HOSPITAL, ISTANBUL, TURKEY
D-Dimer Levels And Acute Pulmonary Embolism Development In Covid-19 Patients, Vural Ahmet, Kahraman Ahmet Nedim
Journal of Mind and Medical Sciences
Objective. To identify those who develop pulmonary embolism with Ddimer levels by evaluating pulmonary CT angiographies of patients who are followed up with suspicion of coronavirus disease 2019 (COVID-19). Methods. Patients who were followed up in a community hospital with suspicion of COVID-19 and underwent Pulmonary CT angiography examination were evaluated. Clinical and demographic parameters and DDimer values for patients with and without pulmonary embolism were evaluated in the pulmonary CT angiogram. Results. During the COVID-19 pandemic, Thorax CT examination was performed in our center for suspicion or follow-up of COVID-19 infection in 3396 patients. Pulmonary CT angiography was applied ...
Covid-19 Newsletter (Vol. 66),
2021
Touro College and University System
Covid-19 Newsletter (Vol. 66), Center For Disaster Medicine, New York Medical College
COVID-19 Newsletter
No abstract provided.
Global Impact Of The Covid-19 On Stroke Care,
2021
Emory University
Global Impact Of The Covid-19 On Stroke Care, Svin Covid-19 Global Registry, Raul Nogueira, Ajit S. Puri, Anna L. Kuhn, Thanh Nguyen
COVID-19 Publications by UMMS Authors
BACKGROUND: The COVID-19 pandemic led to profound changes in the organization of health care systems worldwide.
AIMS: We sought to measure the global impact of the COVID-19 pandemic on the volumes for mechanical thrombectomy (MT), stroke, and intracranial hemorrhage (ICH) hospitalizations over a 3-month period at the height of the pandemic (March 1 to May 31, 2020) compared with two control 3-month periods (immediately preceding and one year prior).
METHODS: Retrospective, observational, international study, across 6 continents, 40 countries, and 187 comprehensive stroke centers. The diagnoses were identified by their ICD-10 codes and/or classifications in stroke databases at participating ...
Decline In Subarachnoid Haemorrhage Volumes Associated With The First Wave Of The Covid-19 Pandemic,
2021
Boston Medical Center
Decline In Subarachnoid Haemorrhage Volumes Associated With The First Wave Of The Covid-19 Pandemic, Thanh N. Nguyen, Ajit S. Puri, Anna L. Kuhn, Raul G. Nogueira
COVID-19 Publications by UMMS Authors
BACKGROUND: During the COVID-19 pandemic, decreased volumes of stroke admissions and mechanical thrombectomy were reported. The study's objective was to examine whether subarachnoid haemorrhage (SAH) hospitalisations and ruptured aneurysm coiling interventions demonstrated similar declines.
METHODS: We conducted a cross-sectional, retrospective, observational study across 6 continents, 37 countries and 140 comprehensive stroke centres. Patients with the diagnosis of SAH, aneurysmal SAH, ruptured aneurysm coiling interventions and COVID-19 were identified by prospective aneurysm databases or by International Classification of Diseases, 10th Revision, codes. The 3-month cumulative volume, monthly volumes for SAH hospitalisations and ruptured aneurysm coiling procedures were compared for the ...
Challenges In Defining Long Covid: Striking Differences Across Literature, Electronic Health Records, And Patient-Reported Information,
2021
University of Colorado
Challenges In Defining Long Covid: Striking Differences Across Literature, Electronic Health Records, And Patient-Reported Information, Halie M. Rando, Feifan Liu, Melissa A. Haendel
UMass Center for Clinical and Translational Science Supported Publications
Since late 2019, the novel coronavirus SARS-CoV-2 has introduced a wide array of health challenges globally. In addition to a complex acute presentation that can affect multiple organ systems, increasing evidence points to long-term sequelae being common and impactful. The worldwide scientific community is forging ahead to characterize a wide range of outcomes associated with SARS-CoV-2 infection; however the underlying assumptions in these studies have varied so widely that the resulting data are difficult to compare. Formal definitions are needed in order to design robust and consistent studies of Long COVID that consistently capture variation in long-term outcomes. Even the ...
