Open Access. Powered by Scholars. Published by Universities.®

Psychiatry Commons

Open Access. Powered by Scholars. Published by Universities.®

1,825 Full-Text Articles 5,476 Authors 1,542,428 Downloads 79 Institutions

All Articles in Psychiatry

Faceted Search

1,825 full-text articles. Page 3 of 76.

Insulin Resistance And Oxidative Stress: In Relation To Cognitive Function And Psychopathology In Drug-Naive, First-Episode Drug-Free Schizophrenia, Qi Tao, Yu Miao, Huihui Li, Xiuxia Yuan, Xufeng Huang, Yunpeng Wang, Ole A. Andreassen, Xiaoduo Fan, Yongfeng Yang, Xueqin Song 2020 Zhengzhou University

Insulin Resistance And Oxidative Stress: In Relation To Cognitive Function And Psychopathology In Drug-Naive, First-Episode Drug-Free Schizophrenia, Qi Tao, Yu Miao, Huihui Li, Xiuxia Yuan, Xufeng Huang, Yunpeng Wang, Ole A. Andreassen, Xiaoduo Fan, Yongfeng Yang, Xueqin Song

Open Access Publications by UMMS Authors

Objective: The present study aimed to examine whether insulin resistance and oxidative stress are associated with cognitive impairment in first-episode drug-free schizophrenia (SZ) patients.

Methods: Ninety first-episode SZ patients and 70 healthy controls were enrolled. Fasting insulin (FINS) and markers of oxidative stress [oxidized glutathione (GSSG), superoxide dismutase (SOD), nitric oxide (NO) and uric acid (UA) levels] were measured in serum before pharmacological treatment was initiated. Psychiatric symptoms and cognitive function were assessed with the Positive and Negative Syndrome Scale (PANSS) and MATRICS Consensus Cognitive Battery (MCCB), respectively. In addition, the homeostatic model assessment of insulin resistance (HOMA-IR) was also ...


Reflecting On The First Year Of A N Ew Psychiatric Econsult Service, Katherine B. Martin MD, Edward R. Norris MD, FAPA, FAPM, Rory L. Marraccini MD, Shanthi P. Lewis MD, Cecilia E. Zemanek BS 2020 Lehigh Valley Health Network

Reflecting On The First Year Of A N Ew Psychiatric Econsult Service, Katherine B. Martin Md, Edward R. Norris Md, Fapa, Fapm, Rory L. Marraccini Md, Shanthi P. Lewis Md, Cecilia E. Zemanek Bs

Department of Psychiatry

No abstract provided.


Mindfulness And Behavior Change, Zev Schuman-Olivier, Marcelo Trombka, David A. Lovas, Judson A. Brewer, David R. Vago, Richa Gawande, Julie P. Dunne, Sara W. Lazar, Eric B. Loucks, Carl E. Fulwiler 2020 Harvard Medical School

Mindfulness And Behavior Change, Zev Schuman-Olivier, Marcelo Trombka, David A. Lovas, Judson A. Brewer, David R. Vago, Richa Gawande, Julie P. Dunne, Sara W. Lazar, Eric B. Loucks, Carl E. Fulwiler

Psychiatry Publications

Initiating and maintaining behavior change is key to the prevention and treatment of most preventable chronic medical and psychiatric illnesses. The cultivation of mindfulness, involving acceptance and nonjudgment of present-moment experience, often results in transformative health behavior change. Neural systems involved in motivation and learning have an important role to play. A theoretical model of mindfulness that integrates these mechanisms with the cognitive, emotional, and self-related processes commonly described, while applying an integrated model to health behavior change, is needed. This integrative review (1) defines mindfulness and describes the mindfulness-based intervention movement, (2) synthesizes the neuroscience of mindfulness and integrates ...


Reliability And Validity Of The Rs14 In Orphaned And Separated Adolescents And Youths In Western Kenya, Sarah C. Sutherland, Harry S. Shannon, David Ayuku, David L. Streiner, Olli Saarela, Lukoye Atwoli, Paula Braitstein 2020 University of Toronto, Canada

Reliability And Validity Of The Rs14 In Orphaned And Separated Adolescents And Youths In Western Kenya, Sarah C. Sutherland, Harry S. Shannon, David Ayuku, David L. Streiner, Olli Saarela, Lukoye Atwoli, Paula Braitstein

Internal Medicine, East Africa

Purpose: The 14-item Resilience Scale (RS14) is a tool designed to measure psychological resilience. It has been used effectively in diverse populations. However, its applicability is largely unknown for Sub-Saharan adolescent populations and completely unknown for orphaned and separated adolescents and youths (OSAY), a highly vulnerable population for whom resilience may be critical. This study assesses the RS14's psychometric properties for OSAY in Uasin Gishu County, Kenya.

Methods: Survey responses from a representative sample of 1016 OSAY (51.3% female) aged 10-25 (mean = 16; SD = 3.5) living in institutional and home-based environments in Uasin Gishu County were analyzed ...


Perampanel-Induced Cataplexy In A Young Male With Generalized Epilepsy, Kelsey Kenaan, Mohsin Zafar, Ronnie Bond, Barbara L. Gracious 2020 Edward Via College of Osteopathic Medicine

Perampanel-Induced Cataplexy In A Young Male With Generalized Epilepsy, Kelsey Kenaan, Mohsin Zafar, Ronnie Bond, Barbara L. Gracious

HCA Healthcare Journal of Medicine

Perampanel (Fycompa) is a newer anti-epileptic drug believed to exert its effects in the central nervous system by inhibiting post-synaptic glutamate receptors. However, the precise therapeutic mechanism is unknown. The most common neuropsychiatric side effect is affective dysregulation; there are also reports of psychosis. We describe a 32 year old African American male with recurring generalized tonic-clonic (GTC) seizures, who presented to our hospital with onset of mood lability for several months, after Perampanel was added to his antiepileptic medications. Perampanel administration was temporarily withheld, and subsequently on restarting, noted to be coincident with neuropsychiatric symptomatology, including motor weakness in ...


Supporting Family Members Of Youth In Mental Health Crisis, Joshua Feriante, Maite Cintron, Ariella Shayani, Brian Denietolis, Emily Lauer, David M. Cochran, Yael Dvir, Emily Rubin 2020 University of Massachusetts Medical School

Supporting Family Members Of Youth In Mental Health Crisis, Joshua Feriante, Maite Cintron, Ariella Shayani, Brian Denietolis, Emily Lauer, David M. Cochran, Yael Dvir, Emily Rubin

University of Massachusetts Medical School Publications

The Sibling Support Program: A Family-Centered Mental Health Initiative, developed at the E.K. Shriver Center of UMass Medical School, addresses the impact of a youth’s mental health challenges on typically-developing siblings and caregivers. The project is an IRB-approved research study at Cambridge Health Alliance, and the principles of the project have been implemented at three sites in Worcester that provide gradated levels of care, ranging from residential to community-based. Findings show that regardless of the severity of a child’s mental health challenges, as evidenced by the level of care the child receives, family members display a similar ...


Association Of Depression And Resilience With Fertility Quality Of Life Among Patients Presenting To The Infertility Centre For Treatment In Karachi, Pakistan, Shireen Shehzad Bhamani, Nida Zahid, Wajeeha Zahid, Salima Farooq, Saima Sachwani, Marilyn Chapman, Nargis Asad 2020 Aga Khan University

Association Of Depression And Resilience With Fertility Quality Of Life Among Patients Presenting To The Infertility Centre For Treatment In Karachi, Pakistan, Shireen Shehzad Bhamani, Nida Zahid, Wajeeha Zahid, Salima Farooq, Saima Sachwani, Marilyn Chapman, Nargis Asad

School of Nursing & Midwifery

Background: In Pakistan there is a dire need to explore the quality of life in infertile males and females and its undesirable psychological outcomes. This, study aimed to compare the quality of life (QoL) of males and females visiting an infertility centre for treatment and to assess its association with resilience, depression, and other socio-demographic factors.
Methods: An Analytical Cross-Sectional study was conducted amongst infertile males and females at the Australian Concept Infertility Medical Centre (ACIMC), Karachi, Pakistan. The non-probability (purposive) sampling strategy was used to recruit the participants. The sample size was 668. Data was analysed using STATA version ...


Clinical Approach To A Request For Phentermine-Topiramate In A Young Woman With A History Of High-Risk Eating Behavior, Erin Spencer 2020 Wayne State University School of Medicine

Clinical Approach To A Request For Phentermine-Topiramate In A Young Woman With A History Of High-Risk Eating Behavior, Erin Spencer

Clinical Research in Practice: The Journal of Team Hippocrates

A clinical decision report appraising Safer DL, Adler S, Dalai SS, et al. A randomized, placebo-controlled crossover trial of phentermine-topiramate ER in patients with binge-eating disorder and bulimia nervosa. Int J Eat Disord. 2019;(September):1-12. https://doi.org/10.1002/eat.23192 to inform the clinical decision of whether or not to prescribe phentermine-topiramate to an overweight 27-year-old woman who endorses risky eating behaviors.


The Reliability, Validity And Factorial Structure Of The Swahili Version Of The 7-Item Generalized Anxiety Disorder Scale (Gad-7) Among Adults Living With Hiv From Kilifi, Kenya, Moses K. Nyongesa, Paul Mwangi, Hans M. Koot, Pim Cuijpers, Charles R. J. C. Newton, Amina Abubakar 2020 KEMRI, Kilifi, Kenya

The Reliability, Validity And Factorial Structure Of The Swahili Version Of The 7-Item Generalized Anxiety Disorder Scale (Gad-7) Among Adults Living With Hiv From Kilifi, Kenya, Moses K. Nyongesa, Paul Mwangi, Hans M. Koot, Pim Cuijpers, Charles R. J. C. Newton, Amina Abubakar

Institute for Human Development

Background: Generalized Anxiety Disorder (GAD) is under-investigated in people living with HIV/AIDS from sub-Saharan Africa. In part, this is due to paucity of culturally appropriate measures for GAD which are psychometrically robust. This study aimed to evaluate the reliability, factorial structure, and validity of Swahili version of the 7-item GAD questionnaire (GAD-7) among adults living with HIV.

Study design: Descriptive cross-sectional study.

Methods: 450 adults receiving comprehensive care from an HIV specialized clinic in Kilifi County, coastal Kenya, were consecutively recruited. Swahili versions of GAD-7, Patient Health Questionnaire (PHQ-9) and a 12-item HIV stigma scale were administered alongside measures ...


Carbamazepine-Induced Dress Syndrome: A Case Report, Andrada Luciana Lazar, Olga Hilda Orășan, Corina Baican, Nicolae Voicu Rednic, Adela Sitar-Tăut, Bogdan Man, Vasile Negrean, Nicolae Rednic, Angela Cozma 2020 DEPARTMENT OF DERMATOLOGY, ‘IULIU HAŢIEGANU’ UNIVERSITY OF MEDICINE AND PHARMACY CLUJ-NAPOCA

Carbamazepine-Induced Dress Syndrome: A Case Report, Andrada Luciana Lazar, Olga Hilda Orășan, Corina Baican, Nicolae Voicu Rednic, Adela Sitar-Tăut, Bogdan Man, Vasile Negrean, Nicolae Rednic, Angela Cozma

Journal of Mind and Medical Sciences

Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a potentially life-threatening, idiosyncratic, acute adverse drug reaction. Fever, morbilliform cutaneous eruption, and eosinophilia are essential features for the diagnosis of this syndrome, along with significant multisystem involvement, hepatitis being the most common, followed by nephritis. The pathogenesis of DRESS syndrome is not yet fully understood. Several hypotheses have been proposed which support the involvement of an intricate interplay of multiple factors. We report a clinical case of DRESS syndrome with renal injury, induced by carbamazepine, in a patient with alcohol abstinence syndrome. In order to define the case, the ...


When Myocardial Infarction Is Choosing Young Victims, Cristina Nedelcu, Mihaela Ionescu, Paris Ionescu, Vitalie Morosanu, Gabriel Smarandache, Dumitru Cristinel Badiu, Florentina Gherghiceanu, Vlad Denis Constantin, Emanuele Maria Merlo, Daniel Niţă 2020 ARMY CENTER FOR CARDIOVASCULAR DISEASES, CONSTANTA, ROMANIA

When Myocardial Infarction Is Choosing Young Victims, Cristina Nedelcu, Mihaela Ionescu, Paris Ionescu, Vitalie Morosanu, Gabriel Smarandache, Dumitru Cristinel Badiu, Florentina Gherghiceanu, Vlad Denis Constantin, Emanuele Maria Merlo, Daniel Niţă

Journal of Mind and Medical Sciences

We present the case of a 31-year-old patient, without cardiovascular risk factors, without significant pathological or family history of cardiovascular disease, who was diagnosed with severe coronary artery disease, left main bifurcation localization, which required surgical coronary revascularization. The angiographic and intraoperative aspect excluded the most common causes of non-atherosclerotic causes of coronary lesions. Vasculitis was another possible etiology but was also excluded based on the normal clinical examination, negative inflammation markers, lack of diffuse vascular impairment, TPHA and negative VDRL. Prolonged mental stress can lead to accelerated progression of atherosclerosis by inducing endothelial dysfunction, our patient describing a “burnout ...


Covid-19 Outbreak Impact On Plastic Surgery Residents From Romania, Cristina N. Marina, Daniela E. Gheoca-Mutu, Laura Răducu, Adelaida Avino, Lăcrămioara A. Brîndușe, Corina M. Stefan, Razvan V. Scaunasu, Cristian R. Jecan 2020 CAROL DAVILA UNIVERSITY OF MEDICINE AND PHARMACY, FACULTY OF GENERAL MEDICINE, DEPARTMENT OF PLASTIC AND RECONSTRUCTIVE SURGERY, BUCHAREST, ROMANIA

Covid-19 Outbreak Impact On Plastic Surgery Residents From Romania, Cristina N. Marina, Daniela E. Gheoca-Mutu, Laura Răducu, Adelaida Avino, Lăcrămioara A. Brîndușe, Corina M. Stefan, Razvan V. Scaunasu, Cristian R. Jecan

Journal of Mind and Medical Sciences

The COVID-19 outbreak triggered a global crisis with long-term effects on people’s daily lives. It has altered surgical practice and education and imposed major changes in healthcare systems and resources. In order to analyze the impact the COVID-19 pandemic has had on Romanian Plastic Surgery residents, we carried out an anonymous questionnaire through Google forms. Survey items addressed aspects such as how the pandemic has affected their surgical practice, their exposure to the virus, and the protective measures that have been implemented to minimize risk. Among other results, our study found that nearly 1 in 5 respondents had contact ...


The Quality Of Sexual Life After Vaginal Surgical Interventions, Maria Pană, Romina-Marina Sima, Oana-Denisa Bălălău, Anca-Daniela Stănescu, Liana Pleş, Mircea-Octavian Poenaru 2020 CAROL DAVILA UNIVERSITY OF MEDICINE AND PHARMACY, BUCHAREST, ROMANIA

The Quality Of Sexual Life After Vaginal Surgical Interventions, Maria Pană, Romina-Marina Sima, Oana-Denisa Bălălău, Anca-Daniela Stănescu, Liana Pleş, Mircea-Octavian Poenaru

Journal of Mind and Medical Sciences

Introduction. The malfunction of the supporting pelvic system generates signs and symptoms that require various procedures. The aim of our study was to evaluate whether vaginal surgical interventions for genital prolapse or urinary incontinence have an impact on patients’ sexual quality of life. Materials and methods. We studied 40 eligible women who underwent vaginal surgical procedures in Saint John Hospital, Bucharest. Patients completed a questionnaire 6 months after the intervention. Results. Patients who underwent vaginal surgery for prolapse were 50-64 years of age. The most frequent vaginal surgical intervention was vaginal hysterectomy (32.5%), followed by anterior and posterior colporaphy ...


Work Place Impact On Mental Wellbeing Of Frontline Doctors, Vishnupriya Veeraraghavan, Krishnan Srinivasan 2020 AARUPADAI VEEDU MEDICAL COLLEGE AND HOSPITAL, DEPARTMENT OF PSYCHIATRY, PUDUCHERRY, INDIA

Work Place Impact On Mental Wellbeing Of Frontline Doctors, Vishnupriya Veeraraghavan, Krishnan Srinivasan

Journal of Mind and Medical Sciences

Background. Coronavirus Disease 2019 (COVID-19, also known as 2019-nCoV), a cluster of acute respiratory illness with unknown causes, has occurred in India since January 2020. Over the past several months, the entire world is struggling to cope with and contain the virus spread. Several studies showed that mental health problems could occur in both healthcare workers and SARS survivors during the SARS epidemic. Considering the geographical variation, dense population, multi-strata health care structure, and rising COVID cases in South India, we have a reason to speculate that the burden on the frontline doctors is high and their psychological condition may ...


Indicators Of Psychological Distress And Body Image Disorders In Female Patients With Breast Cancer, Helena van Oers, Lourens Schlebusch 2020 DURBAN ONCOLOGY CENTRE, DURBAN, SOUTH AFRICA

Indicators Of Psychological Distress And Body Image Disorders In Female Patients With Breast Cancer, Helena Van Oers, Lourens Schlebusch

Journal of Mind and Medical Sciences

Breast cancer patients are vulnerable to elevated stress related to receiving the diagnosis, unfamiliar and invasive treatment, and coping with the side-effects of treatment, which may find various forms of expression. Another common feature of this patient population is body image dysphoria. Both the disease and treatment lead to impairments in physical appearance and general bodily functioning. This study aimed to explore the differential manifestations of stress and the nature of body image dysphoria within a sample of female breast cancer patients (n=80), compared to female patients with other sites of disease (n=80) in order to examine differences ...


Assessing Test Anxiety And Resilience Among Greek Adolescents During Covid-19 Pandemic, Sofia Sakka, Vasiliki Aliki Nikopoulou, Eleni Bonti, Paraskevi Tatsiopoulou, Panayiota Karamouzi, Aikaterini Giazkoulidou, Virginia Tsipropoulou, Eleni Parlapani, Vasiliki Holeva, Ioannis Diakogiannis 2020 DEPARTMENT OF PSYCHIATRY, SCHOOL OF MEDICINE, ARISTOTLE UNIVERSITY OF THESSALONIKI, THESSALONIKI, GREECE

Assessing Test Anxiety And Resilience Among Greek Adolescents During Covid-19 Pandemic, Sofia Sakka, Vasiliki Aliki Nikopoulou, Eleni Bonti, Paraskevi Tatsiopoulou, Panayiota Karamouzi, Aikaterini Giazkoulidou, Virginia Tsipropoulou, Eleni Parlapani, Vasiliki Holeva, Ioannis Diakogiannis

Journal of Mind and Medical Sciences

The aim of the present study was to explore the impact of school year’s extension due to the coronavirus pandemic (COVID-19) by addressing test anxiety and by studying the coping strategies adolescents used to overcome it. For the majority of the adolescents the final exams can be a powerful source of stress, since the entrance examinations are required for admission into higher education and further reflect the transition to adulthood. The sample consisted of 67 High School students and the data collection was conducted online due to the imposed measures by the Greek government. Results showed normal or average ...


Implementing Nudges For Suicide Prevention In Real-World Environments: Project Inspire Study Protocol, Molly Davis, Courtney Benjamin Wolk, Shari Jager-Hyman, Rinad S Beidas, Jami F Young, Jennifer A Mautone, Alison M Buttenheim, David S Mandell, Kevin G Volpp, Katherine Wislocki, Anne Futterer, Darby Marx, E L Dieckmeyer, Emily M Becker-Haimes 2020 University of Pennsylvania

Implementing Nudges For Suicide Prevention In Real-World Environments: Project Inspire Study Protocol, Molly Davis, Courtney Benjamin Wolk, Shari Jager-Hyman, Rinad S Beidas, Jami F Young, Jennifer A Mautone, Alison M Buttenheim, David S Mandell, Kevin G Volpp, Katherine Wislocki, Anne Futterer, Darby Marx, E L Dieckmeyer, Emily M Becker-Haimes

College of Life Sciences Faculty Papers

Background: Suicide is a global health issue. There are a number of evidence-based practices for suicide screening, assessment, and intervention that are not routinely deployed in usual care settings. The goal of this study is to develop and test implementation strategies to facilitate evidence-based suicide screening, assessment, and intervention in two settings where individuals at risk for suicide are especially likely to present: primary care and specialty mental health care. We will leverage methods from behavioral economics, which involves understanding the many factors that influence human decision making, to inform strategy development.

Methods: We will identify key mechanisms that limit ...


Solute Carrier Family 1 (Slc1a1) Contributes To Susceptibility And Psychopathology Symptoms Of Schizophrenia In The Han Chinese Population, Wenqiang Li, Xi Su, Tengfei Chen, Zhen Li, Yongfeng Yang, Luwen Zhang, Qing Liu, Minglong Shao, Yan Zhang, Minli Ding, Yanli Lu, Hongyan Yu, Xiaoduo Fan, Meng Song, Luxian Lv 2020 Xinxiang Medical University

Solute Carrier Family 1 (Slc1a1) Contributes To Susceptibility And Psychopathology Symptoms Of Schizophrenia In The Han Chinese Population, Wenqiang Li, Xi Su, Tengfei Chen, Zhen Li, Yongfeng Yang, Luwen Zhang, Qing Liu, Minglong Shao, Yan Zhang, Minli Ding, Yanli Lu, Hongyan Yu, Xiaoduo Fan, Meng Song, Luxian Lv

Psychiatry Publications

Objective: Schizophrenia (SZ) is a common and complex psychiatric disorder that has a significant genetic component. The glutamate hypothesis describes one possible pathogenesis of SZ. The solute carrier family 1 gene (SLC1A1) is one of several genes thought to play a critical role in regulating the glutamatergic system and is strongly implicated in the pathophysiology of SZ. In this study, we identify polymorphisms of the SLC1A1 gene that may confer susceptibility to SZ in the Han Chinese population.

Methods: We genotyped 36 single-nucleotide polymorphisms (SNPs) using Illumina GoldenGate assays on a BeadStation 500G Genotyping System in 528 paranoid SZ patients ...


Effects Of Preexisting Psychotropic Medication Use On A Cohort Of Patients With Ischemic Stroke Outcome, Adalia H. Jun-O'Connell, Dilip K. Jayaraman, Nils Henninger, Brian Silver, Majaz Moonis, Anthony J. Rothschild 2020 University of Massachusetts Medical School

Effects Of Preexisting Psychotropic Medication Use On A Cohort Of Patients With Ischemic Stroke Outcome, Adalia H. Jun-O'Connell, Dilip K. Jayaraman, Nils Henninger, Brian Silver, Majaz Moonis, Anthony J. Rothschild

University of Massachusetts Medical School Faculty Publications

Background: Several studies investigated the use of selective serotonin reuptake inhibitors (SSRI) after ischemic stroke to improve motor recovery. However, little is known about the effects of preexisting psychotropic medication use (PPMU), such as antidepressants, on a long-term ischemic stroke functional disability.

Objective: We sought to determine the prevalence of PPMU and whether PPMU relates to the long-term clinical outcome in a cohort of patients presenting with acute ischemic strokes.

Methods: We retrospectively analyzed 323 consecutive patients who presented with an acute ischemic stroke in a single institution between January 2015 and December 2017. Baseline characteristics, functional disability as measured ...


Psychiatric Symptomatology, Mood Regulation, And Resting State Functional Connectivity Of The Amygdala: Preliminary Findings In Youth With Mood Disorders And Childhood Trauma, Yael Dvir, David N. Kennedy, Steven M. Hodge, Destiny Pegram, Brian Denietolis, Jean A. Frazier 2020 University of Massachusetts Medical School

Psychiatric Symptomatology, Mood Regulation, And Resting State Functional Connectivity Of The Amygdala: Preliminary Findings In Youth With Mood Disorders And Childhood Trauma, Yael Dvir, David N. Kennedy, Steven M. Hodge, Destiny Pegram, Brian Denietolis, Jean A. Frazier

Psychiatry Publications

Background: As mood dysregulation and hyperarousal are overlapping and prominent features of posttraumatic stress disorder (PTSD), and mood disorders (MD) including bipolar disorder (BD), we aimed to clarify the role of trauma and MD on the resting state functional connectivity (RSFC) of amygdala in MD youth with or without trauma exposure, and healthy controls (HC).

Methods: Of 23 subjects, 21 completed the magnetic resonance imaging (MRI) protocol, 5 were excluded for subject motion, leaving final sample size of 16: nine subjects with MD (5/9 with trauma), and 7 HC. Youth were assessed with Schedule for Affective Disorders and Schizophrenia ...


Digital Commons powered by bepress