Neurology Commons^™

What Is Better Antiplatelet Agent To Prevent Recurrent Stroke?, Muhammad Faisal Wadiwala, Ayeesha Kamran Kamal

Department of Medicine

No abstract provided.

Morphological And Genetic Activation Of Microglia After Diffuse Traumatic Brain Injury In The Rat, Tuoxin Caou, Amanda M. Lisembee, Kelley D. Hall, James R. Pauly, Jonathan Lifshitz

Kaleidoscope

Traumatic brain injury (TBI) survivors experience long, term post-traumatic morbidities. In diffuse brain injured rats, a chronic sensory sensitivity to whisker stimulation models agitation in brain injury survivors and provides anatomical landmarks across the whisker-barrel circuit to evaluate traumatic neuropathology. As a consequence of TBI, acute and chronic microglial activation can contribute to degenerative and reparative events underlying post-traumatic morbidity. Here, we hypothesize that delayed microglial activation is concomitant with neuroplastic change after diffuse brain injury in the rat, by examining differential microglial activation states and neuroplasticity through gene and protein expression. Adult male, Sprague-Dawley rats were subjected to a …

Neurosurgical Applications Of Magnetic Resonance Diffusion Tensor Imaging, Daniel D. Hirsch, Bs, Benjamin M. Zussman, Bs, Adam E. Flanders, Md, Ashwini D. Sharan, Md

JHN Journal

Magnetic Resonance (MR) Diffusion Tensor Imaging (DTI) is a rapidly evolving technology that enables the visualization of neural fiber bundles, or white matter (WM) tracts. There are numerous neurosurgical applications for MR DTI including: (1) Tumor grading and staging; (2) Pre-surgical planning (determination of resectability, determination of surgical approach, identification of WM tracts at risk); (3) Intraoperative navigation (tumor resection that spares WM damage, epilepsy resection that spares WM damage, accurate location of deep brain stimulation structures); (4) Post-operative assessment and monitoring (identification of WM damage, identification of tumor recurrence). Limitations of MR DTI include difficulty tracking small and crossing …

Extending The Window For Thrombolysis In Acute Stroke., Muhammad Faisal Wadiwala,, Ayeesha Kamran Kamal

Department of Medicine

No abstract provided.

Undergraduate Neurosurgical Learning Opportunities At Jefferson, Leadership Committee Neurosurgery Student Interest Group

JHN Journal

On the evening of November 29, 2011, Jefferson’s Neurosurgery Interest Group (NSIG) hosted fourteen Jefferson Medical College students for a technical course entitled “Foundations in Neurosurgery” taught by Dr. Ashwini Sharan, Associate Professor of Neurosurgery and Director of the Division of Functional Neurosurgery, and Dr. Joshua Heller, Assistant Professor of Neurosurgery at Thomas Jefferson University Hospital. Additional instructors included Jefferson neurosurgery residents Rohan Chitale (PGY5), Chengyuan Wu (PGY4), and Karl Balsara (PGY2). Stryker MedED provided equipment, models, and instructors Ryan Dugan and Devin Opdendyk (Figure 1).

Complications Of Decompressive Craniectomy, Sandra Ho, Bs, Yinn C. Ooi, Md, Muhamad A. Sheikh, Mbbs, Mitchell Maltenfort, Phd, Jack Jallo, Md, Phd

JHN Journal

Introduction:

Persistent elevation of intracranial pressure (ICP), if untreated, may lead to brain ischemia or lack of brain oxygen and even brain death.1-6,10 When standard treatments for elevated ICP are exhausted without any signs of improvement, decompressive craniectomy can be an effective alternative solution.7,19 Decompressive craniectomies (DC) have been used as a method of controlling intracranial pressure in patients with cerebral edema secondary to cerebral ischemia, subarachnoid hemorrhage (SAH), and traumatic brain injury (TBI), among others. 8-10 Several studies over the years have demonstrated the efficacy of this procedure.7-9,11,35,36 However, consensus is still lacking in the utility of DC as …

Fractionated Stereotactic Radiosurgery Alone For The Treatment Of A Papillary Craniopharygioma, Tyler J. Kenning, Md, James J. Evans, Md

JHN Journal

The use of radiation treatment (RT) is usually reserved for residual or recurrent craniopharyngiomas, and the role of RT alone and not as an adjunctive therapy to surgery has not been clearly defined. The authors describe a case of a 50-year-old man presenting with a large suprasellar craniopharyngioma with extension into the third ventricle, producing acute hydrocephalus. A ventriculoperitoneal shunt was performed concurrently with an endoscopic biopsy. Treatment with fractionated stereotactic radiosurgery (FSR) resulted in near resolution of the lesion with no evidence of recurrence over six years. A review of RT for the treatment of craniopharyngiomas without surgical resection …

Diagnostic Potential Of The Nmda Receptor Peptide Assay For Acute Ischemic Stroke, Svetlana A. Dambinova, Kerstin Bettermann, Theodore Glynn, Matthew Tews, David Olsen, Joseph D. Weissman, Richard K. Sowell

Faculty Articles

Background

The acute assessment of patients with suspected ischemic stroke remains challenging. The use of brain biomarker assays may improve the early diagnosis of ischemic stroke. The main goal of the study was to evaluate whether the NR2 peptide, a product of the proteolytic degradation of N-methyl-D-aspartate (NMDA) receptors, can differentiate acute ischemic stroke (IS) from stroke mimics and persons with vascular risk factors/healthy controls. A possible correlation between biomarker values and lesion sizes was investigated as the secondary objective.

Methods and Findings

A total of 192 patients with suspected stroke who presented within 72 h of symptom onset …

Neurosurgical Electives: Operating Room Survival Guide, M Shahzad Shamim, Zain A. Sobani

Section of Neurosurgery

No abstract provided.

Large Vessel Atherosclerotic Infarction And Headache, Farhad Iranmanesh, Faranak Gadari

Pakistan Journal of Neurological Sciences (PJNS)

No abstract provided.

Migrainous Vertigo And Pseudovertigo In Migraine Without Aura, At A Headache Clinic, Lnam-E -Khuda, Mohammad Abdullah, Ismail A. Khatri

Pakistan Journal of Neurological Sciences (PJNS)

No abstract provided.

Diffusion Tractography In Spinal Cord Injury: Preliminary Experience, Vikas Bhattia, R.G Sood, Sanjiv Sharma, Prashant Panda

Pakistan Journal of Neurological Sciences (PJNS)

No abstract provided.

Long-Term Effect Of Carotid Surgery In Asymptomatic Stenosis., Muhammad Faisal Wadiwala, Ayeesha Kamran Kamal

Department of Medicine

No abstract provided.

Vitamin D Deficiency In Parkinsons Disease Patients At A Tertiary Care Center In Karachi, Pakistan, Adnan Yousuf, Sarwar Jamil Siddiqui, Iqbal Azam, Mohammad Wasay

Pakistan Journal of Neurological Sciences (PJNS)

No abstract provided.

Psychiatry, Haider A. Naqvi Dr.

Pakistan Journal of Neurological Sciences (PJNS)

No abstract provided.

Limitations Of F-18 Fog Pet/Ct In Excluding Bilateral Palatine Tonsillar Metastases, Allen Missoi, Amolak Singh

Pakistan Journal of Neurological Sciences (PJNS)

No abstract provided.

Neurosurgery, Muhammad Mehboob Alam Dr.

Pakistan Journal of Neurological Sciences (PJNS)

No abstract provided.

Neurology Curriculum For Medical Students In Pakistan – Scope And Priorities, Ismail A. Khatri, Maimoona Siddiqui

Pakistan Journal of Neurological Sciences (PJNS)

No abstract provided.

Neuroradiology, Zafar Sajjad

Pakistan Journal of Neurological Sciences (PJNS)

No abstract provided.

Diffusion Weighted Mr Imaging Of The Brain: Review Of Clinical Applications, Muhammad Azeemuddin, Rohana Naqi, Mohammad Wasay

Pakistan Journal of Neurological Sciences (PJNS)

No abstract provided.