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Gender Differences In Urothelial Bladder Cancer: Effects Of Natural Killer Lymphocyte Immunity, Charles T. Lutz, Lydia Livas, Steven R. Presnell, Morgan Sexton, Peng Wang 2021 University of Kentucky

Gender Differences In Urothelial Bladder Cancer: Effects Of Natural Killer Lymphocyte Immunity, Charles T. Lutz, Lydia Livas, Steven R. Presnell, Morgan Sexton, Peng Wang

Pathology and Laboratory Medicine Faculty Publications

Men are more likely to develop cancer than women. In fact, male predominance is one of the most consistent cancer epidemiology findings. Additionally, men have a poorer prognosis and an increased risk of secondary malignancies compared to women. These differences have been investigated in order to better understand cancer and to better treat both men and women. In this review, we discuss factors that may cause this gender difference, focusing on urothelial bladder cancer (UBC) pathogenesis. We consider physiological factors that may cause higher male cancer rates, including differences in X chromosome gene expression. We discuss how androgens may promote …


A Telephone-Adapted Mindfulness-Based Stress Reduction Program: Preliminary Effects Among Healthcare Employees, Lauren A Zimmaro, Aleeze Sattar Moss, Diane K. Reibel, Elizabeth A Handorf, Jennifer B Reese, Carolyn Y Fang 2021 Fox Chase Cancer Center

A Telephone-Adapted Mindfulness-Based Stress Reduction Program: Preliminary Effects Among Healthcare Employees, Lauren A Zimmaro, Aleeze Sattar Moss, Diane K. Reibel, Elizabeth A Handorf, Jennifer B Reese, Carolyn Y Fang

Marcus Institute of Integrative Health Faculty Papers

Healthcare employees often experience high stress and may benefit from accessible psychosocial interventions. In this pilot study, we explored preliminary feasibility, acceptability, and psychological effects of a telephone-based adaption of mindfulness-based stress reduction (MBSR) for healthcare employees. Eleven participants (M age = 49.9; 27.3% ethnic/racial minority) were enrolled in an eight-session group-based MBSR program adapted for telephone delivery. Feasibility was assessed using rates of program attrition and session completion; acceptability was explored qualitatively via participants' responses to an open-ended item about their program experience. Participants also completed pre-and post-program assessments on psychosocial outcomes (distress (overall distress, depression, anxiety, somatization), mindfulness, …


Neuroendocrine Carcinoma Of The Breast: A Case Report, Iulia Gîvan, George Ciulei, Angela Cozma, Mădălina Gabriela Indre, Vlad Țâru, Anca Pop, Adela Sitar Tăut, Simina Țărmure, Vasile Negrean, Olga Hilda Orășan 2021 NICULAIE STĂNCIOIU HEART INSTITUTE CLUJ NAPOCA, CLUJ NAPOCA, ROMANIA

Neuroendocrine Carcinoma Of The Breast: A Case Report, Iulia Gîvan, George Ciulei, Angela Cozma, Mădălina Gabriela Indre, Vlad Țâru, Anca Pop, Adela Sitar Tăut, Simina Țărmure, Vasile Negrean, Olga Hilda Orășan

Journal of Mind and Medical Sciences

Neuroendocrine breast carcinomas represent a rare subtype of breast cancer. Their definition, prevalence and prognosis remain controversial in the literature. Regarding the presentation, there are no differences from other breast carcinomas and clinical syndromes related to hormone production are extremely rare. Refinement of the classification of neuroendocrine neoplasms of the breast is needed in order to improve the reproducibility of their diagnostic criteria and to define their clinical significance.

This article presents the case of a 44-year-old female patient diagnosed with invasive breast carcinoma with neuroendocrine features, according to the 2012 World Health Organization (WHO) definition, with focus on presentation, …


Desire For Control Moderates The Relationship Between Perceived Control And Depressive Symptomology, Liam Alexander MacKenzie Myles, Emanuele Maria Merlo, Antonia Obele 2021 UNIVERSITY OF CAMBRIDGE, DEPARTMENT OF PSYCHOLOGY, CAMBRIDGE, UNITED KINGDOM

Desire For Control Moderates The Relationship Between Perceived Control And Depressive Symptomology, Liam Alexander Mackenzie Myles, Emanuele Maria Merlo, Antonia Obele

Journal of Mind and Medical Sciences

Background. The prevalence of psychological difficulties is rising at an alarming rate, with an increasing number of individuals reporting symptoms of depression. A decline in both perceived control and desire for control has previously been associated with the onset of depression. However, previous research has failed to examine whether perceived control and desire for control interact in their relationship with depressive symptomology. Methods. A sample of 350 participants completed the Spheres of Control Scale, the Desirability of Control Scale and Beck’s Depression Inventory. Process Macro was used to examine whether desire for control moderated the relationship between perceived …


Effect Of Presence And Absence Of Parents On The Emotional Maturity And Perceived Loneliness In Adolescents, Sana Fatima, Momal Bashir, Kainat Khan, Sheeza Farooq, Sidra Shoaib, Sheeba Farhan 2021 BAHRIA UNIVERSITY, KARACHI CAMPUS, NATIONAL STADIUM RD, KARACHI, PAKISTAN

Effect Of Presence And Absence Of Parents On The Emotional Maturity And Perceived Loneliness In Adolescents, Sana Fatima, Momal Bashir, Kainat Khan, Sheeza Farooq, Sidra Shoaib, Sheeba Farhan

Journal of Mind and Medical Sciences

The present study was conducted to examine the Emotional Maturity and Perceived Loneliness of adolescents with respect to the presence and absence of parents. It was hypothesized that the absence or presence of parents of adolescents would affect the level of emotional maturity and perceived loneliness among adolescents. The adolescent participants N=250 (males n=125 and females n=125; age range= 13-18; M=16.63; SD=0.87) were approached through purposive convenient sampling technique. Measures included the Emotional Maturity Scale and the UCLA loneliness scale V-III. Results indicated that adolescent who lived with their guardians had greater perceived loneliness than those who lived with their …


Role Of Emotional Intelligence In Job Performance Of Healthcare Providers Working In Public Sector Hospitals Of Pakistan, Nimra Zaman, Khalida Naz Memon, Faryal Zaman, Komal Zaman Khan, Shazia Rahman Shaikh 2021 LIAQUAT UNIVERSITY OF MEDICAL AND HEALTH SCIENCES, DEPARTMENT OF COMMUNITY MEDICINE AND PUBLIC HEALTH SCIENCES, JAMSHORO, PAKISTAN

Role Of Emotional Intelligence In Job Performance Of Healthcare Providers Working In Public Sector Hospitals Of Pakistan, Nimra Zaman, Khalida Naz Memon, Faryal Zaman, Komal Zaman Khan, Shazia Rahman Shaikh

Journal of Mind and Medical Sciences

Objective. To determine the association between emotional intelligence (EI) and job performance (JP) of health care providers (HCPs). Methods. Healthcare professionals from various hospitals were chosen for a cross-sectional study. The survey was conducted using a three-part questionnaire including the demographic profile, Wong and Law Emotional Intelligence (EI) Scale, and an individual work performance (JP) questionnaire. The relationship of predictor variables on JP was sought by applying Chi-square test and multiple regression analysis. Results. About 43.3% of the 50.8% of participants who scored well on the EI scale also scored high on the JP scales. The remaining …


Therapeutic Efficacy Of Mesenchymal Stem Cells For Cardiovascular Diseases, Dragana Radoje Miloradovic, Dragica Radoje Pavlovic, Miodrag Bozidar Stojkovic, Sanja Bratislav Bojic, Vladislav Bogdan Volarevic, Marina Milosav Gazdic Jankovic, Biljana Tomislav Ljujic 2021 UNIVERSITY OF KRAGUJEVAC, FACULTY OF MEDICAL SCIENCES, DEPARTMENT OF GENETICS, SERBIA

Therapeutic Efficacy Of Mesenchymal Stem Cells For Cardiovascular Diseases, Dragana Radoje Miloradovic, Dragica Radoje Pavlovic, Miodrag Bozidar Stojkovic, Sanja Bratislav Bojic, Vladislav Bogdan Volarevic, Marina Milosav Gazdic Jankovic, Biljana Tomislav Ljujic

Journal of Mind and Medical Sciences

Despite the improvements in pharmacological and surgical treatments, cardiovascular diseases (CVDs) are the number one cause of death worldwide. During the last two decades, the search for new therapies has been revolutionized with the growing knowledge of stem cell biology. Due to their huge differentiation capacity and paracrine effects, mesenchymal stem cells (MSCs) are a promising tool for the treatment of CVDs. The encouraging outcomes of preclinical studies using MSCs as a treatment for diseased myocardium have set the scene for worldwide clinical trials. In this review, we overview either complete or ongoing clinical trials using MSCs for the therapy …


Food Addiction And Obesity, Lisa Ling 2021 Abilene Christian University

Food Addiction And Obesity, Lisa Ling

Electronic Theses and Dissertations

The obesity rate in the U.S. adult population has increased to epidemic levels despite attempts to decrease obesity through evidence-based knowledge, clinical practice guidelines, medical interventions, and individual efforts. For certain individuals, food addiction behaviors such as food cravings, loss of control, and binge eating contribute to obesity and require a different approach to care. Little work has been done on adding the possibility of food addiction to obesity screening and treatment. This study utilized a quasi-experimental quantitative pre- and postsurvey research design based on Lewin’s change theory. Nurse practitioners were surveyed regarding the provider’s perceptions, attitudes, and beliefs about …


Medical Schools Ignore The Nature Of Consciousness At Great Cost, Anoop Kumar 2021 independent scholar

Medical Schools Ignore The Nature Of Consciousness At Great Cost, Anoop Kumar

Journal of Wellness

The essential question of the relationship between consciousness and matter is ignored in medical school curricula, leading to a machine-like view of the human being that contributes to physician burnout and intellectual dissatisfaction. The evidence suggesting that the brain may not be the seat of consciousness is generally ignored to preserve the worldview of the primacy of matter. By investigating new frameworks detailing the nature of consciousness at different levels of hierarchy, we can bring intellectual rigor to a once opaque subject that supports a fundamental reality about our experience: We are human beings, not only human bodies.


Music As A Gateway To Healing Speech Disorders And Mental Health Holistically In The Patient With Aphasia: A Literature Review, susan warren 2021 Lesley University

Music As A Gateway To Healing Speech Disorders And Mental Health Holistically In The Patient With Aphasia: A Literature Review, Susan Warren

Expressive Therapies Capstone Theses

People with some types of post-stroke aphasia often experience depression as well as loss of speech. Music therapy has unique properties that allow it to be used therapeutically to treat both speech impairment and depression yet it is rarely used to treat both disorders. This literature review seeks to examine the underlying causes for this discrepancy, review methods used by practitioners to treat both disorders and suggest future directions for additional research and implications for the treatment of patients with aphasia who have both language impairment and depression.


A Holistic Approach To Physical And Mental Health: Associations Between Chronic Disease And Psychiatric Conditions, Pooja Patel, Alison Mancuso 2021 Rowan University

A Holistic Approach To Physical And Mental Health: Associations Between Chronic Disease And Psychiatric Conditions, Pooja Patel, Alison Mancuso

Rowan-Virtua Research Day

OBJECTIVE:

• To investigate the link between chronic medical conditions and psychiatric disorders

BACKGROUND

• Limited research has been done studying the relationship between chronic medical conditions and psychiatric disorders in patients comorbid with both types of conditions.

• Prior research studies have demonstrated that patients with chronic medical conditions are more likely to develop psychiatric disorders compared to healthy individuals without any medical conditions.

• As individuals develop chronic medical conditions, they may encounter additional obstacles in their lives,


Pathological Mechanisms Of Vacuolar Aggregate Myopathy Arising From A Casq1 Mutation, Amy D Hanna, Chang Seok Lee, Lyle Babcock, Hui Wang, Joseph Recio, Susan L Hamilton 2021 The Texas Medical Center Library

Pathological Mechanisms Of Vacuolar Aggregate Myopathy Arising From A Casq1 Mutation, Amy D Hanna, Chang Seok Lee, Lyle Babcock, Hui Wang, Joseph Recio, Susan L Hamilton

Faculty, Staff and Students Publications

Mice with a mutation (D244G, DG) in calsequestrin 1 (CASQ1), analogous to a human mutation in CASQ1 associated with a delayed onset human myopathy (vacuolar aggregate myopathy), display a progressive myopathy characterized by decreased activity, decreased ability of fast twitch muscles to generate force and low body weight after one year of age. The DG mutation causes CASQ1 to partially dissociate from the junctional sarcoplasmic reticulum (SR) and accumulate in the endoplasmic reticulum (ER). Decreased junctional CASQ1 reduces SR Ca


Restructuring The Gut Microbiota By Intermittent Fasting Lowers Blood Pressure, Huanan Shi, Bojun Zhang, Taylor Abo-Hamzy, James W Nelson, Chandra Shekar R Ambati, Joseph F Petrosino, Robert M Bryan, David J Durgan 2021 The Texas Medical Center Library

Restructuring The Gut Microbiota By Intermittent Fasting Lowers Blood Pressure, Huanan Shi, Bojun Zhang, Taylor Abo-Hamzy, James W Nelson, Chandra Shekar R Ambati, Joseph F Petrosino, Robert M Bryan, David J Durgan

Faculty, Staff and Students Publications

Rationale:

In recent years, it has been demonstrated that a pathological change in the gut microbiota, termed gut dysbiosis, can be an underlying factor for the development of hypertension. Prevention of this dysbiosis can attenuate or abolish hypertension. Translational mechanisms to prevent gut dysbiosis as well as understanding of the mechanisms linking gut dysbiosis to hypertension are lacking.

Objective:

We first examined the efficacy of intermittent fasting (IF) in altering the gut microbiota and lowering blood pressure (BP). Next, we utilized a multi-omics approach to examine microbial influenced metabolites that may serve as the link between the gut microbiota and …


Aching For Sacred Spaces, Arjun Mann 2021 University of New England, College of Osteopathic Medicine

Aching For Sacred Spaces, Arjun Mann

Akesis

This image was made in early 2021, inside a local cafe that was operating takeout-only. It is a space that is very dear to me, one in which I spent countless hours (pre-pandemic) studying and reading, rejuvenating and relaxing with friends.

Recently, as I browsed books while waiting for a latte to-go, this scene caught my eye. The warm light pouring in through a large window fell over my favorite table, marked as "unavailable" by the chairs perched upon it. It would remain, understandably, unavailable for months to come. I was reminded, as I so often am these days, of …


Aurora Stronger, Sarah J. Stengle 2021 University of New England

Aurora Stronger, Sarah J. Stengle

Akesis

For my Integrate Clinical Experience class, we were asked to complete journal entries based on our experiences, podcasts, and/or APTA modules. This was one of my entries about a podcast on allyship in the field of physical therapy that can also be applied to any medical field. The podcast can be found at http://podcast.healthywealthysmart.com/pod-cast/ episode 499. This entry is about my personal experience during the peaceful protests and riot that ensued after the unjust murder of George Floyd. Dr. Adrienne McAuley suggested I submit this work to Akesis to share my experience and my personal beliefs change after I decided …


Resignation, Kaline E. Mulvihill 2021 University of New England

Resignation, Kaline E. Mulvihill

Akesis

I have struggled with anxiety and depression for most of my life. At first, I didn't understand it. Then, I was embarrassed by it. I chose to hide my struggle. It became my own silent battle. A battle I was slowly losing. In March of 2020, the world shut down. A dark, suffocating cloud began to settle over all of us. Life as we knew it, completely changed. At first, I thought I was handling the drastic life changes. I thought I was simply adapting. Then it happened, I lost control. My body physically prevented me from sleeping. It was …


The After Math, Amy L. Courtney 2021 University of New England

The After Math, Amy L. Courtney

Akesis

Poetry reflecting on the COVID-19 pandemic


How Covid-19 Showed Me The Importance Of Patient Education, Katie Lamar 2021 Nova Southeastern University

How Covid-19 Showed Me The Importance Of Patient Education, Katie Lamar

Akesis

This is a personnal reflection upon how COVID-19 impacted me and highlighted to me the importance of patient education.


Heart-Healthy Integrative Nutritional Counseling Group Education Sessions Among Chinese Americans With Cardiovascular Risk Factors Or Disease: A Primary Care Quality Improvement Pilot, Jasmin Woo, Evelyn Y. Ho, Jane Jih 2021 University of California, San Francisco

Heart-Healthy Integrative Nutritional Counseling Group Education Sessions Among Chinese Americans With Cardiovascular Risk Factors Or Disease: A Primary Care Quality Improvement Pilot, Jasmin Woo, Evelyn Y. Ho, Jane Jih

Journal of Patient-Centered Research and Reviews

Purpose: Current biomedical cardiovascular disease nutrition counseling does not incorporate Chinese medicine principles.

Methods: A heart-healthy integrative nutritional counseling (H2INC) curriculum consistent with Chinese medicine principles and biomedical nutrition guidelines was taught to Chinese Americans in group education sessions. Chinese-speaking patients with cardiovascular disease or risk factors from an urban general medicine practice were recruited to attend a 90-minute group session. Participants completed pre-post surveys to assess the impact of H2INC on their perceived heart-healthy nutrition knowledge and empowerment, as well as the cultural relevance of H2INC.

Results: A total of 47 participants (mean age: 74 years; 63.8% female) attended …


D-Dimer Levels And Acute Pulmonary Embolism Development In Covid-19 Patients, Vural Ahmet, Kahraman Ahmet Nedim 2021 DEPARTMENT OF RADIOLOGY, UNIVERSITY OF HEALTH SCIENCE FATIH SULTAN MEHMET TRAINING AND RESEARCH HOSPITAL, ISTANBUL, TURKEY

D-Dimer Levels And Acute Pulmonary Embolism Development In Covid-19 Patients, Vural Ahmet, Kahraman Ahmet Nedim

Journal of Mind and Medical Sciences

Objective. To identify those who develop pulmonary embolism with Ddimer levels by evaluating pulmonary CT angiographies of patients who are followed up with suspicion of coronavirus disease 2019 (COVID-19). Methods. Patients who were followed up in a community hospital with suspicion of COVID-19 and underwent Pulmonary CT angiography examination were evaluated. Clinical and demographic parameters and DDimer values for patients with and without pulmonary embolism were evaluated in the pulmonary CT angiogram. Results. During the COVID-19 pandemic, Thorax CT examination was performed in our center for suspicion or follow-up of COVID-19 infection in 3396 patients. Pulmonary CT angiography was applied …


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