Integrative Medicine Commons^™

Losartan Rescues Inflammation-Related Mucociliary Dysfunction In Relevant Models Of Cystic Fibrosis, Michael D Kim, Nathalie Baumlin, Makoto Yoshida, Deepika Polineni, Sebastian F Salathe, Joseph K David, Charles A Peloquin, Adam Wanner, John S Dennis, Juliette Sailland, Philip Whitney, Frank T Horrigan, Juan R Sabater, William M Abraham, Matthias Salathe

Faculty, Staff and Students Publications

Rationale: Despite therapeutic progress in treating cystic fibrosis (CF) airway disease, airway inflammation with associated mucociliary dysfunction remains largely unaddressed. Inflammation reduces the activity of apically expressed large-conductance Ca²⁺-activated and voltage-dependent K⁺ (BK) channels, critical for mucociliary function in the absence of CFTR (CF transmembrane conductance regulator).

Objectives: To test losartan as an antiinflammatory therapy in CF using CF human bronchial epithelial cells and an ovine model of CF-like airway disease.

Methods: Losartan’s antiinflammatory effectiveness to rescue BK activity and thus mucociliary function was tested in vitro using primary, fully redifferentiated human airway epithelial cells homozygous for …

A Feasibility Study Of Lavender Aromatherapy In An Awake Craniotomy Environment, Kailah Cathey, Nichole Gunyon, Nancy Chung, Nancy Conway, Diane Ames, Maharaj Singh, Amin B. Kassam, Richard A. Rovin

Journal of Patient-Centered Research and Reviews

Purpose: Integrative medicine interventions are needed for awake craniotomies, as many patients experience anxiety. Lavender aromatherapy significantly reduces anxiety or pain in a variety of surgical procedures. This feasibility study used lavender aromatherapy during awake craniotomies to determine the number of patients who would consent and complete the study, the technicality of lavender aromatherapy use, and acceptance by operating room (OR) staff.

Methods: We approached 40 consecutive patients (≥18 years old). Exclusion criteria were pulmonary issues or sensitivity to lavender. Outcome measures in consented patients were enrollment and completion rates, anxiety and pain as measured by the Visual Analog Scale …

Lavender Aromatherapy: Ready For Prime-Time Office Use?, Dennis J. Baumgardner

Journal of Patient-Centered Research and Reviews

The editor-in-chief of Journal of Patient-Centered Research and Reviews comments on the perioperative use of lavender aromatherapy and its potential to relieve pain and anxiety during minor primary care office procedures.

Hx Of, Bonni Boles

Akesis

My purpose in creating this comic strip was to tell a story that depicts some of the struggles I have had with the health care system and how a patient's history can go overlooked. I suffered from chronic insomnia for over 10 years before a licensed professional counselor, someone tasked with actually listening to me, helped me to get on medication to help with sleep. My mental health, and general health, problems became much less severe and more manageable after finally sleeping regularly.

Sleep hygiene has been found to not have much success with chronic insomnia. I didn't need someone …

Skull And Cervical Spine Study, Paul J. Mangiafico

Akesis

Anatomical drawings are a really fun way to understand and appreciate the structure and the complexity of the human body. The material used to create this drawing was a #2 mechanical pencil.

Twin, Amy L. Courtney

Akesis

Reflective essay about being an identical twin who no longer looks identical.

Remedy, Michael Cyr

Akesis

In keeping with this issues’ theme this piece is meant to highlight the subtle places terminal illness hides biologically, socially and spiritually and how and where it is expressed, sometimes despite the best efforts of the patient or caregivers. This piece also makes effort to convey the importance of humanity in medicine and highlight loving connection as an important part of the arsenal we use against sickness.

Hexis Habitus, Jessica Rehrig

Akesis

This photograph is one that was taken years ago after gymnastics practice. It was mindlessly taken: poor quality, out of frame, buried amongst memories saved in a rarely viewed album. At the time, it captured nothing more than a habitus, a commonplace that seemed unnecessary to freeze in time.

Years have passed since training, and our hands no longer serve as an outward reflection of diligence and dedication. Today those calluses exist in the internal habitus of our character, and in one mindlessly taken, poor quality, out of frame photograph.

Clay And Stone, Jess W. Rempel

Akesis

Clay handprints on a canyon wall in southern Utah, found after the people who made them had gone. The Navajo sandstone of the canyon wall dates to the Jurassic period, with a record of eons revealed by the water that carved the canyon away. People love to leave their mark on places that make marks on them: some of the earliest recorded graffiti in Pompeii simply read "Gaius was here." I enjoyed stumbling upon the hand prints which allowed me into the hikers' experience, and their joy could add to the lasting impression that place made upon me. Our experiences …

Corporeal Quintessence, Jordan Lamb, Michael Cyr

Akesis

In keeping with the theme of “Historia Habitus” this collection is meant to illustrate how the physical form is a living history, with every movement written into the striations of the human musculature. The old adage “you are what you eat” is easily extended to “you are what you do”. Contemplate the hours and repetitions that have gone into sculpting the highlighted regions of our model/athletes. We hope this collection stimulates reflection on what the body can tell you about your past and what your, or perhaps your patient’s, lifestyle can predict about the future.

The Journey Of Life, Rolene Yousefyan

Akesis

The materials used to create this piece were oil pastels. The inspiration behind this piece was the importance of mental health awareness along with our ability to grow and become who we are today based on our past experiences and history.

Our Histories, Our Horizons: A Letter To Our Readers

Akesis

Volume 5, Issue 1 marks a new chapter in the history of our narrative medicine journal as we realize an important goal of Akesis—establishing a foothold on the Portland campus of UNE. Our hope is that Akesis becomes a familiar name among students, faculty, and staff, and that our call for submissions and issue publications are events everyone anticipates and enjoys. This issue also welcomes six new editors to Akesis, students representing a diverse sampling of UNE’s graduate and professional programs from both campuses. The success of this issue’s call for submissions is due to the efforts of …

Insights Into The Pathogenesis Of Nicotine Addiction. Could A Salivary Biosensor Be Useful In Nicotine Replacement Therapy (Nrt)?, Anida-Maria Băbțan, Nausica B. Petrescu, Anca Ionel, Bianca A. Boșca, Willi A. Uriciuc, Claudia N. Feurdean, Codruța I. Mirică, Roxana Bordea, Viorel Miclăuș, Flavia Ruxanda, Adina D. Todea, Teodora G. Alexescu, Radu S. Câmpian, Aranka Ilea

Journal of Mind and Medical Sciences

Nicotine has gained the attention of the medical community due to its insidious addictive mechanisms which lead to chronic consumption. The multitude of compounds derived from tobacco smoke have local and systemic negative impacts, resulting in a large number of smoking-related pathologies. The present review offers insights into nicotine addiction physiopathology, as well as social and medical implications, with emphasis on its correlation with Advanced Glycation End Products (AGEs). Therapeutic strategies and new approaches to nicotine assessment and cessation treatment are discussed, noting that such strategies could take into account the possibility of slow and gradual nicotine release from a …

Introduction Of Auricular Acupuncture, Monica Lyons

Doctoral Projects

The overall purpose of this quality improvement project was to assess if there was an interest to add auricular acupuncture to a substance abuse program. The two guiding questions of the Doctor of Nursing Project were (a) how can auricular acupuncture be helpful when treating patients with substance abuse in a selected organization? (b) what information is needed for both staff and patients to make an informed decision regarding auricular acupuncture? The Promoting Action on Research Implementation in Health Services (PARiHS) framework was used as the theory framework for implementation of evidence-based research into an organization. The facilitator in the …

Chronic Renal Failure, But Why? A Case Report., Palak Patel, Michael Rothberg

Rowan-Virtua Research Day

Renal failure, both acute and chronic, can present from many different etiologies and if diagnosed with diabetes mellitus, it is commonly assumed to be due to diabetic nephropathy. Monoclonal gammopathy of renal significance (MGRS) is a disorder that combines monoclonal gammopathy of undetermined significance with end stage renal disease. Monoclonal immunoglobulins are secreted by B or plasma cells leading to deposition in the kidney causing end organ damage. Several different subtypes fall under this category of renal diseases including, but not limited to, amyloidosis, C3 glomeruopathy, and light chain proximal tubulopathy, or better known as Fanconi syndrome1. Fanconi syndrome, which …

An Integrative Approach To Mindfulness-Based Symptom Management For Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, Lisa Barer

Mindfulness Studies Theses

Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a chronic health condition; its etiology is poorly understood, and treatment options are limited to management of symptoms. Current recommended treatment options are controversial, and evidence of effectiveness is limited. This paper proposes a novel model for symptom management of ME/CFS using mindfulness-based interventions, cognitive behavioural therapy (CBT), and relaxation techniques. A comprehensive review of available evidence is used to support this approach. The idea is that, working synergistically, these three approaches, grounded by mindfulness-based principles, can address many of the symptoms of the illness and help patients better cope and manage their day-to-day …

Utilization Of Acupuncture Services In The Emergency Department Setting: A Quality Improvement Study, John R. Burns, Jessica J. F. Kram, Vashir Xiong, Jeanne M. Stark Casadont, Tiffany A. Mullen, Nancy Conway, Dennis J. Baumgardner

Journal of Patient-Centered Research and Reviews

Purpose: Patients often present to the emergency department (ED) for pain. As opioid fatalities rise, alternative treatments are warranted for pain management. Acupuncture, a nonpharmacological treatment involving the insertion of needles into skin or tissue at specific points within the body, may help to decrease acute pain. Our study aimed to assess the utilization and impact of acupuncture in the ED for acute pain management.

Methods: We conducted a retrospective analysis of purposefully collected quality improvement data. Patients who were ≥18 years old and who presented to the ED at an urban medical center in Wisconsin during 2017 were offered …

Oncogenesis- Kaleidoscopic And Multi-Level Reality, Firmilian Calota, Cristian Mesina, Stelian Stefanita Mogoanta, Dragos Calota

Journal of Mind and Medical Sciences

Oncogenesis is an extremely complex phenomenon. The mechanisms by which cancer is induced is only partially known. Consequently, therapeutic targets may be uncertain and results are often unsatisfactory. The purpose of this paper is to develop a trans-level and multiple transdisciplinary perspective describing the kaleidoscopic reality of oncogenesis. This manner of understanding oncogenesis as a complex process characterized by a non-linear dynamic, far from equilibrium and with unpredictable evolution, transcends the classical perspective and requires a paradigm shift. This approach is also facilitated by recent studies that focus on group phenomena, with emerging behaviors in a continuous phase transition. Biological …

Overcoming The Overwhelming, Abigail Mae Riitano

Akesis

This piece was inspired by a CPC prompt that required reflection on where we feel we are currently as medical students and how it compares to our expectations before starting medical school. I believe this relates to the theme "always forward" as I reflected on my expectations and realized that I need to give my positive perspectives room to grow.

Not Now, Psoas., Kelly Mcguirl

Akesis

My psoas is always tight.

Sometimes I’m too intense.

My psoas reminds me with a collegial cramp.

Usually on my dominant side.

I notice, but push through, telling my psoas to shut the hell up, I’m busy.

When it’s quiet,

I notice and allow the guidance.

I soften and submit to a gentleness of mind and muscle.

The ease that comes is an honest breeze that carries me through.