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Association Of Presenting Symptoms With Abnormal Laboratory Values For Vector-Borne Illness — Experience In An Urban Gastroenterology Practice, Michael D. Erdman, Niloofar Kossari, Jessica Ye, Kristen H. Reynolds, Emily Blodget, B. Robert Mozayeni, Farshid Sam Rahbar 2021 Los Angeles Integrative Gastroenterology & Nutrition

Association Of Presenting Symptoms With Abnormal Laboratory Values For Vector-Borne Illness — Experience In An Urban Gastroenterology Practice, Michael D. Erdman, Niloofar Kossari, Jessica Ye, Kristen H. Reynolds, Emily Blodget, B. Robert Mozayeni, Farshid Sam Rahbar

Journal of Patient-Centered Research and Reviews

Background: In the clinical setting, it is not common practice to consider a vector bite, such as from a tick or flea, to be a contributing factor to chronic digestive symptoms. This article investigates associations we have observed among symptomatic patients and positive blood tests for vector-borne illness (VBI).

Methods: Patients who visited an urban gastroenterology clinic over a 3-year period were retrospectively reviewed. A total of 270 patients presenting with a constellation of digestive symptoms — and who had no apparent digestive pathology and reported no prior diagnosis or treatments for VBI — were analyzed. Before the initial visit, all patients ...


Covid-19 And Acute Esophageal Obstruction Management In The Emergency Department: An U.S. Multicenter Research Network Propensity-Matched Analysis, Hemant Goyal MD FACP, Abhilash Perisetti MD FACP, Mahesh Gajendran MD MPH FACP, Aman Ali MD, Neil Sharma MD 2021 Parkview Health

Covid-19 And Acute Esophageal Obstruction Management In The Emergency Department: An U.S. Multicenter Research Network Propensity-Matched Analysis, Hemant Goyal Md Facp, Abhilash Perisetti Md Facp, Mahesh Gajendran Md Mph Facp, Aman Ali Md, Neil Sharma Md

Other Specialties

Introduction- The Coronavirus Disease-2019 (COVID-19) caused by the novel SARS-CoV-2 led to significant strain on the Emergency Department (ED) visits worldwide. Multiple stay-at-home orders were issued during the pandemic unless medical treatment was urgently needed1 . Acute esophageal obstruction (AEO) due to food/ foreign body impaction usually present to the ED, given its severe symptoms. Most esophageal foreign bodies pass through the gastrointestinal (GI) tract uneventfully, and related mortality is very low. Still, most of these patients receive endoscopic interventions (up to 76%)2 . The number of non-urgent endoscopies plummeted sharply during the pandemic to reduce exposure and preserve personal protective ...


Outcomes In Children And Adolescents Undergoing Cholecystectomies With A High Ejection Fraction, Salony Dighamber, Karen Herzing, Arturo Aranda, Jeffrey C. Pence, Sean Barnett 2021 Wright State University - Main Campus

Outcomes In Children And Adolescents Undergoing Cholecystectomies With A High Ejection Fraction, Salony Dighamber, Karen Herzing, Arturo Aranda, Jeffrey C. Pence, Sean Barnett

Scholarship in Medicine - All Papers

Background

Cholecystectomy is commonly performed electively for symptomatic cholelithiasis and biliary hypokinesia with an ejection fraction (EF) less than 35%. Recent literature has shown that cholecystectomy in adults for biliary hyperkinesia (EF>65%) can provide resolution of symptoms (primarily pain) for the majority of patients. We seek to determine whether cholecystectomy is efficacious in the treatment of symptomatic biliary hyperkinesia in the pediatric population.

Method

The charts of over 100 patients aged 7 to 21 in the last 10 years (2008 to 2018) who had cholecystectomies were reviewed to determine ejection fraction, BMI, race, pain with CCK-HIDA, complications, and resolution ...


Challenges During Colonoscopy In Women With A Prior Hysterectomy, Lubna Kamani, Nazish Butt, Hanisha Khemani 2021 Aga Khan University

Challenges During Colonoscopy In Women With A Prior Hysterectomy, Lubna Kamani, Nazish Butt, Hanisha Khemani

Section of Gastroenterology

No abstract provided.


Case Of Enterococcus Cecorum Human Bacteremia, United States, Alexander D. Lake, Ryan Fields, Francia Guerrero, Yousef Almuzaini, Koravangala Sundaresh, Joseph Staffetti 2020 Regional Medical Center Bayonet Point

Case Of Enterococcus Cecorum Human Bacteremia, United States, Alexander D. Lake, Ryan Fields, Francia Guerrero, Yousef Almuzaini, Koravangala Sundaresh, Joseph Staffetti

HCA Healthcare Journal of Medicine

Enterococcus cecorum rarely serves as a human pathogen, and only 6 cases of this microbe inoculating humans have been documented. We present an elderly female with a marked vascular history presenting with epigastric pain and diarrhea, followed by shaking chills. Laboratory findings revealed leukocytosis, with imaging showing diffuse colonic thickening. She had a bout of bloody diarrhea, raising the likelihood of ischemic colitis with her vascular history. To our surprise, both sets of blood cultures drawn on admission grew Enterococcus cecorum. This case is unique as it is the first documented case of E. cecorum human infection in the United ...


Goblet Cell Carcinoma Of The Appendix: A Case Report On Goblet Cell Carcinoid, Sheliza Kabani, Aubtin Saedi, Austin Lehr, Lina O'Brien 2020 Menorah Medical Center

Goblet Cell Carcinoma Of The Appendix: A Case Report On Goblet Cell Carcinoid, Sheliza Kabani, Aubtin Saedi, Austin Lehr, Lina O'Brien

HCA Healthcare Journal of Medicine

Goblet cell carcinoid of the appendix is a rare neoplasm with histological features of both neuroendocrine and adenocarcinomas. The combination of its aggressive behavior, infrequent occurrence, and variable clinical presentation convolutes the management of this tumor. We report the case of a 75-year-old female presenting with acute appendicitis. A laparoscopic appendectomy was performed. The pathology report showed goblet cell carcinoid at the base of the appendix with involvement of the proximal surgical margins. At her postoperative visit, the patient’s pathology report and options for management were reviewed, and the patient agreed to proceed with a right hemicolectomy 8-10 weeks ...


Improved Tolerability And Efficaciousness Of Miralax-Gatorade When Compared To Golytely In The Outpatient Setting, Bassem Farah 2020 Wayne State University School of Medicine

Improved Tolerability And Efficaciousness Of Miralax-Gatorade When Compared To Golytely In The Outpatient Setting, Bassem Farah

Clinical Research in Practice: The Journal of Team Hippocrates

A clinical decision report using Gu P, Lew D, Jung OS, et al. Comparing the Real-World Effectiveness of Competing Colonoscopy Preparations: Results of a Prospective Trial. Am J Gastroenterol. 2019;114(2):305-314. https://doi.org/10.14309/ajg.0000000000000057 for a patient reluctant to undergo colonoscopy screening due to concerns about GoLYTLEY's tolerability.


Liver Cancer-Specific Serine Protease Inhibitor Kazal Is A Potentially Novel Biomarker For The Early Detection Of Hepatocellular Carcinoma, Felix Lu, Pir Ahmad Shah, Abhishek Rao, Cynthia Gifford-Hollingsworth, Anne Chen, Gary Trey, Mina Soryal, Arslan Talat, Aysha Aslam, Bilal Nasir, Saad Choudhry, Rizwan Ishtiaq, Hanna Sanoff, Lanla F Conteh, Anne Noonan, Ke-Qin Hu, Carl Schmidt, Janssen Research & Development, Jesse M. Civan, Gary Xiao, Daryl T-Y Lau, Xuanyong Lu 2020 ImCare Biotech LLC

Liver Cancer-Specific Serine Protease Inhibitor Kazal Is A Potentially Novel Biomarker For The Early Detection Of Hepatocellular Carcinoma, Felix Lu, Pir Ahmad Shah, Abhishek Rao, Cynthia Gifford-Hollingsworth, Anne Chen, Gary Trey, Mina Soryal, Arslan Talat, Aysha Aslam, Bilal Nasir, Saad Choudhry, Rizwan Ishtiaq, Hanna Sanoff, Lanla F Conteh, Anne Noonan, Ke-Qin Hu, Carl Schmidt, Janssen Research & Development, Jesse M. Civan, Gary Xiao, Daryl T-Y Lau, Xuanyong Lu

Division of Gastroenterology and Hepatology Faculty Papers

Introduction: Liver cancer-secreted serine protease inhibitor Kazal (LC-SPIK) is a protein that is specifically elevated in cases of hepatocellular carcinoma (HCC). We assessed the performance of LC-SPIK in detecting HCC, including its early stages, in patients with cirrhosis, hepatitis B virus (HBV), and hepatitis C virus (HCV).

Methods: We enrolled 488 patients, including 164 HCC patients (81 early HCC) and 324 controls in a blinded, prospective, case-control study. Serum LC-SPIK levels were determined by an enzyme-linked immunosorbent assay-based assay. The performance of serum LC-SPIK and α-fetoprotein (AFP), including area under the curve (AUC), sensitivity, and specificity, are compared. The performance ...


Trainee Participation During Screening Colonoscopy Does Not Affect Adr At Subsequent Surveillance, But May Result In Early Follow-Up, Alexander J. Eckardt, Joan Kheder, Anjali Basil, Taryn Silverstein, Krunal Patel, Mohammed Mahmoud, Yasir Al-Azzawi, Daniel Ellis, William Gillespie, Yoel Carrasquillo Vega, Sharina D. Person, John M. Levey 2020 DKD Helios Klinik Wiesbaden

Trainee Participation During Screening Colonoscopy Does Not Affect Adr At Subsequent Surveillance, But May Result In Early Follow-Up, Alexander J. Eckardt, Joan Kheder, Anjali Basil, Taryn Silverstein, Krunal Patel, Mohammed Mahmoud, Yasir Al-Azzawi, Daniel Ellis, William Gillespie, Yoel Carrasquillo Vega, Sharina D. Person, John M. Levey

Population and Quantitative Health Sciences Publications

Background and study aims: Training future endoscopists is essential to meet rising demands for screening and surveillance colonoscopies. Studies have shown conflicting results regarding the influence of trainees on adenoma detection rates (ADR). It is unclear whether trainee participation during screening adversely affects ADR at subsequent surveillance and whether it alters surveillance recommendations.

Patients and methods: A retrospective analysis of average-risk screening colonoscopies and surveillance exams over a subsequent 10-year period was performed. The initial inclusion criteria were met by 5208 screening and 2285 surveillance exams. Patients with poor preparation were excluded. The final analysis included 7106 procedures, including 4922 ...


Gastrointestinal Endoscopy In The Era Of Covid-19, Abhilash Perisetti, Hemant Goyal, Neil Sharma MD 2020 Parkview Health

Gastrointestinal Endoscopy In The Era Of Covid-19, Abhilash Perisetti, Hemant Goyal, Neil Sharma Md

PCI Publications and Projects

Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), which led to a worldwide pandemic that started in early 2020. Healthcare systems across the world encountered an unprecedented surge of COVID-19 patients resulting in more than half a million deaths globally. COVID-19 has affected multiple sub-specialties and procedure-related fields, including gastroenterology. Gastrointestinal (GI) endoscopy centers are specialized units where thousands of endoscopies are performed annually. A significant proportion of these procedures are affected due to the national and regional lockdowns across the globe. To adapt to this rapidly evolving situation, endoscopy centers have undergone significant changes ...


Exploring Peer Mentoring In Pediatric Transition: Perspectives Of Different Stakeholders About Accompanying Patients In Gastroenterology, Guillaume Dumais-Lévesque, Marie-Pascale Pomey 2020 Laval University, Quebec city

Exploring Peer Mentoring In Pediatric Transition: Perspectives Of Different Stakeholders About Accompanying Patients In Gastroenterology, Guillaume Dumais-Lévesque, Marie-Pascale Pomey

Patient Experience Journal

The literature identifies several issues in the pediatric transition, such as the lack of coordination between pediatric and adult settings and young patients who are not exercising independence in the self-management of their disease. The objective of this study is to explore the potential for a pediatric transition program in gastroenterology, introducing an accompanying patient program to support the transition. A qualitative case study was conducted, including semi-structured focus groups and individual interviews with each group involved in the pediatric transition between two centres in Quebec. A thematic analysis of the collected data was performed using QDA Miner v5.1 ...


Associations Between Household-Level Exposures And All-Cause Diarrhea And Pathogen-Specific Enteric Infections In Children Enrolled In Five Sentinel Surveillance Studies, Josh M. Colston, Abu S G. Faruque, M Jahangir Hossain, Debasish Saha, Suman Kanungo, Inácio Mandomando, Muhammad Imran Nisar, Anita K. M. Zaidi, Richard Omore, Zulfiqar Ahmed Bhutta 2020 University of Virginia School of Medicine, Charlottesville, USA.

Associations Between Household-Level Exposures And All-Cause Diarrhea And Pathogen-Specific Enteric Infections In Children Enrolled In Five Sentinel Surveillance Studies, Josh M. Colston, Abu S G. Faruque, M Jahangir Hossain, Debasish Saha, Suman Kanungo, Inácio Mandomando, Muhammad Imran Nisar, Anita K. M. Zaidi, Richard Omore, Zulfiqar Ahmed Bhutta

Department of Paediatrics and Child Health

Diarrheal disease remains a major cause of childhood mortality and morbidity causing poor health and economic outcomes. In low-resource settings, young children are exposed to numerous risk factors for enteric pathogen transmission within their dwellings, though the relative importance of different transmission pathways varies by pathogen species. The objective of this analysis was to model associations between five household-level risk factors-water, sanitation, flooring, caregiver education, and crowding-and infection status for endemic enteric pathogens in children in five surveillance studies. Data were combined from 22 sites in which a total of 58,000 stool samples were tested for 16 specific enteropathogens ...


An Atypical Case Of Necrotizing Fasciitis Secondary To Perforated Cecal Cancer., Laura S Heidelberg, Erica Pettke, Teresa E Wagner, Lauren Angotti 2020 Swedish Colon and Rectal Clinic, Swedish Medical Center, Seattle, WA 98104, USA.

An Atypical Case Of Necrotizing Fasciitis Secondary To Perforated Cecal Cancer., Laura S Heidelberg, Erica Pettke, Teresa E Wagner, Lauren Angotti

Articles, Abstracts, and Reports

Necrotizing fasciitis is an aggressive, life threatening soft tissue infection that requires high index of suspicion for diagnosis. Diagnosis is clinical with management including broad spectrum antibiotics and emergent operative debridement. The majority of cases are secondary to underlying medical processes, local tissue damage, abscess, or inciting procedure, with a paucity of data correlating causation with colon cancer. We describe the case of an 84-year-old man presenting with sepsis of unknown origin who was diagnosed with an atypical presentation of necrotizing fasciitis secondary to a perforated cecal malignancy. His case is unique in that a less virulent polymicrobial infection was ...


Adenoma Detection Rate As A Quality Indicator For Colonoscopy: A Descriptive Cross-Sectional Study From A Tertiary Care Hospital In Pakistan, Mian Shah Yousaf, Shameel Shafqat, Roger Christopher Gill, Asfia Arham Khursheed, Om Parkash 2020 Aga Khan University

Adenoma Detection Rate As A Quality Indicator For Colonoscopy: A Descriptive Cross-Sectional Study From A Tertiary Care Hospital In Pakistan, Mian Shah Yousaf, Shameel Shafqat, Roger Christopher Gill, Asfia Arham Khursheed, Om Parkash

Section of Gastroenterology

Background and study aims: Adenoma detection rate (ADR) is validated for measuring quality of colonoscopy, however there is lack of colorectal cancer (CRC) screening program in South Asia. The purpose of this study is to analyze and review the polyp detection rate (PDR) and ADR and provide insight into the factors that influence them in Pakistan.
Patients and methods: This retrospective, cross-sectional study was performed at the Aga Khan University Hospital, Karachi, Pakistan, on patients ≥ 18 years, who underwent colonoscopy between January 1, 2017 and June 30, 2018.
Results: Of 1985 patients, 59 % were male and 41 % female, with mean ...


Semiautomated Glasgow-Blatchford Bleeding Score Helps Direct Bed Placement For Patients With Upper Gastrointestinal Bleeding., Drew B Schembre, Robson E Ely, Janice M Connolly, Kunjali T Padhya, Rohit Sharda, John J Brandabur 2020 Clinical Transformation, Swedish Medical Center, Seattle, Washington, USA.

Semiautomated Glasgow-Blatchford Bleeding Score Helps Direct Bed Placement For Patients With Upper Gastrointestinal Bleeding., Drew B Schembre, Robson E Ely, Janice M Connolly, Kunjali T Padhya, Rohit Sharda, John J Brandabur

Articles, Abstracts, and Reports

OBJECTIVE: The Glasgow-Blatchford Bleeding Score (GBS) was designed to identify patients with upper gastrointestinal bleeding (UGIB) who do not require hospitalisation. It may also help stratify patients unlikely to benefit from intensive care.

DESIGN: We reviewed patients assigned a GBS in the emergency room (ER) via a semiautomated calculator. Patients with a score ≤7 (low risk) were directed to an unmonitored bed (UMB), while those with a score of ≥8 (high risk) were considered for MB placement. Conformity with guidelines and subsequent transfers to MB were reviewed, along with transfusion requirement, rebleeding, length of stay, need for intervention and death ...


Prevalence, Mechanisms, And Implications Of Gastrointestinal Symptoms In Covid-19, Abhilash Perisetti, Hemant Goyal, Mahesh Gajendran, Umesha Boregowda, Rupinder Mann, Neil Sharma MD 2020 Parkview Health

Prevalence, Mechanisms, And Implications Of Gastrointestinal Symptoms In Covid-19, Abhilash Perisetti, Hemant Goyal, Mahesh Gajendran, Umesha Boregowda, Rupinder Mann, Neil Sharma Md

PCI Publications and Projects

Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. The infection started as an outbreak of pneumonia-like symptoms in Wuhan, China. Within a few weeks, it spread across the entire globe resulting in millions of cases and thousands of deaths. While respiratory symptoms and complications are well-defined and can be severe, non-respiratory symptoms of COVID-19 are increasingly being recognized. Gastrointestinal manifestations such as nausea, vomiting, diarrhea, and abdominal pain have been added to the list of common COVID-19 symptoms. Their prevalence has been increasing, probably due to increased recognition and experience with the pandemic. Furthermore ...


Video Capsule Endoscopy As First Procedure For Acute Gastrointestinal Bleeding: An Approach To Minimizing Exposure To Sars-Cov-2 And Conserving Resources, Shahrad Hakimian, Mark Hanscom, Matthew Petersile, Prashanth Rau, Anne Foley, David R. Cave 2020 University of Massachusetts Medical School

Video Capsule Endoscopy As First Procedure For Acute Gastrointestinal Bleeding: An Approach To Minimizing Exposure To Sars-Cov-2 And Conserving Resources, Shahrad Hakimian, Mark Hanscom, Matthew Petersile, Prashanth Rau, Anne Foley, David R. Cave

COVID-19 Publications by UMMS Authors

Introduction: Video capsule endoscopy (VCE) has been proposed as an alternative triaging tool for diagnosis of hematemesis and non-hematemesis (GIB). Randomized controlled trials have shown higher detection rates of bleeding with VCE when used as the first procedure compared with standard of care (SOC). This approach has been shown to be safe, and well tolerated. VCE is particularly suitable for the diagnosis of GIB in suspected/established SARS-CoV-2 (COVID) patients as it requires minimal patient contact (one staff person) to set up, and it avoids aerosolization and sedation. We used VCE as the first diagnostic modality in hemodynamically stable patients ...


A Young Male With Cholestatic Jaundice Induced By Dymethazine Present In Nutritional Supplement “Xtreme Dmz”, Michal Kloska MD, Reema M. Vaze MD, Travis Magdaleno MD, She-Yan Wong MD 2020 Lehigh Valley Health Network

A Young Male With Cholestatic Jaundice Induced By Dymethazine Present In Nutritional Supplement “Xtreme Dmz”, Michal Kloska Md, Reema M. Vaze Md, Travis Magdaleno Md, She-Yan Wong Md

Department of Medicine

No abstract provided.


Transoral Incisionless Fundoplication In A Treatment Of Refractory Gerd: A Retrospective Experience At A Large Quaternary Care Center, Michal Kloska MD, Abdul Aleem MD, Valery Hrad MD, Hiral N. Shah MD, Scott Beman MD, Shashin Shah MD 2020 Lehigh Valley Health Network

Transoral Incisionless Fundoplication In A Treatment Of Refractory Gerd: A Retrospective Experience At A Large Quaternary Care Center, Michal Kloska Md, Abdul Aleem Md, Valery Hrad Md, Hiral N. Shah Md, Scott Beman Md, Shashin Shah Md

Department of Medicine

No abstract provided.


Successful Treatment Of Splenic Vein Thrombosis Induced Gastric Varices During Pregnancy, Travis Magdaleno MD, Anam Malik MD, She-Yan Wong MD 2020 Lehigh Valley Health Network

Successful Treatment Of Splenic Vein Thrombosis Induced Gastric Varices During Pregnancy, Travis Magdaleno Md, Anam Malik Md, She-Yan Wong Md

Department of Medicine

No abstract provided.


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