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Endoscopic Proximal Adductor Lengthening For Chronic Adductor-Related Groin Pain, S. Bharam, P. V. Bhagat, M. C. Spira, D. A. Klein 2018 Zucker School of Medicine at Hofstra/Northwell

Endoscopic Proximal Adductor Lengthening For Chronic Adductor-Related Groin Pain, S. Bharam, P. V. Bhagat, M. C. Spira, D. A. Klein

Journal Articles

© 2018 Arthroscopy Association of North America Proximal adductor injuries are relatively common groin injuries in athletes. Various tenotomy techniques have been described including open, partial, and percutaneous approaches. Current techniques help most athletes return to sport; however, many develop adductor weakness. Moreover, the procedures lack full visualization of the tendon and do not allow for return to athletes’ preinjury level of play. We describe an endoscopic z-lengthening of the proximal adductor tendon with the potential to minimize complications associated with open procedures such as incisional pain and neurovascular injury while affording a more complete tenotomy than current percutaneous techniques. …


Neuroimaging Of Meckel’S Cave In Normal And Disease Conditions, A. Malhotra, L. Tu, V. B. Kalra, X. Wu, A. Mian, R. Mangla, E. Michaelides, P. Sanelli, D. Gandhi 2018 Zucker School of Medicine at Hofstra/Northwell

Neuroimaging Of Meckel’S Cave In Normal And Disease Conditions, A. Malhotra, L. Tu, V. B. Kalra, X. Wu, A. Mian, R. Mangla, E. Michaelides, P. Sanelli, D. Gandhi

Journal Articles

© 2018, The Author(s). Abstract: Meckel’s cave is a dural recess in the posteromedial portion of the middle cranial fossa that acts as a conduit for the trigeminal nerve between the prepontine cistern and the cavernous sinus, and houses the Gasserian ganglion and proximal rootlets of the trigeminal nerve. It serves as a major pathway in perineural spread of pathologies such as head and neck neoplasms, automatically upstaging tumours, and is a key structure to assess in cases of trigeminal neuralgia. The purpose of this pictorial review is threefold: (1) to review the normal anatomy of Meckel’s cave; (2) to …


Remote Cerebellar Haemorrhage: A Potential Iatrogenic Complication Of Spinal Surgery, Muhammad Atif Naveed, Rajiv Mangla, Hajra Idrees, Rashi I. Mehta 2018 Shaukat Khanum Memorial Cancer Hospital

Remote Cerebellar Haemorrhage: A Potential Iatrogenic Complication Of Spinal Surgery, Muhammad Atif Naveed, Rajiv Mangla, Hajra Idrees, Rashi I. Mehta

Faculty & Staff Scholarship

We report the case of a 51-year-old man with no significant past medical history, who underwent elective revision spinal surgery and subsequently developed intracranial hypotension, remote cerebellar haemorrhage (RCH), and mild hydrocephalus on the fourth postoperative day. Remote cerebellar haemorrhage is a known complication of supratentorial surgery. This iatrogenic phenomenon may also occur following spinal surgery, due to dural tearing and rapid cerebral spinal fluid (CSF) leakage, resulting in intracranial hypotension and cerebellar haemorrhage. This complication may result in severe permanent neurologic sequelae; hence, it is of pertinence to diagnose and manage it rapidly in order to optimise patient outcome.


Compartment Syndrome Of The Hand: A Case Report And Review Of Literature, V. Mehta, V. Chowdhary, C. Lin, M. Jbara, S. Hanna 2018 Northwell Health

Compartment Syndrome Of The Hand: A Case Report And Review Of Literature, V. Mehta, V. Chowdhary, C. Lin, M. Jbara, S. Hanna

Journal Articles

© 2017 The Authors Elevation of pressure within tightly bound myofascial compartments has detrimental consequences if not treated promptly, leading to a loss of circulation, ischemia, myonecrosis, nerve damage, and limb loss. They are commonly seen in the distal upper and lower extremities; however, compartment syndrome of the hand is rarely encountered and prompt recognition can prevent permanent damage and tissue loss. This case study presents a complicated case of compartment syndrome of the hand and discusses the interrelationship between compartment syndrome and rhabdomyolysis. An emphasis is placed on pathophysiology of this relationship to allow a better understanding of the …


Interpreting 123i-Ioflupane Dopamine Transporter Scans Using Hybrid Scores., K. J. Nichols, B. Chen, M. B. Tomas, C. J. Palestro 2018 Zucker School of Medicine at Hofstra/Northwell

Interpreting 123i-Ioflupane Dopamine Transporter Scans Using Hybrid Scores., K. J. Nichols, B. Chen, M. B. Tomas, C. J. Palestro

Journal Articles

Dopamine transporter (DaT) 123I-FP-CIT scans most commonly are interpreted visually. Alternatively, absolute quantitation of radiopharmaceutical uptake may improve scan accuracy. However, neither approach accomodates dependence of striatal uptake on age and gender. We investigated whether demographic indexing of visual and numerical variables improve discrimination of patients with essential tremor (ET), Parkinson's disease (PD), and dementia with Lewy bodies (DLB).Data of 132 consecutive patients undergoing DaT SPECT scans were reviewed retrospectively. The clinical impression in the latest neurology note was utilized as the final clinical diagnosis. Caudate and putamen specific binding ratio (PSBR) were computed. 123I calibration phantoms were constructed to …


Acute Pulmonary Embolism: Endovascular Therapy, S. P. Reis, K. Zhao, N. Ahmad, R. S. Widemon, C. W. Root, S. M. Toomay, J. M. Horowitz, A. K. Sista 2018 Zucker School of Medicine at Hofstra/Northwell

Acute Pulmonary Embolism: Endovascular Therapy, S. P. Reis, K. Zhao, N. Ahmad, R. S. Widemon, C. W. Root, S. M. Toomay, J. M. Horowitz, A. K. Sista

Journal Articles

© Cardiovascular Diagnosis and Therapy. All rights reserved. Pulmonary embolism (PE) is a leading cause of morbidity and mortality worldwide. PE is a complex disease with a highly variable presentation and the available treatment options for PE are expanding rapidly. Anticoagulation (AC), systemic lysis, surgery, and catheter-directed thrombolysis (CDT) play important roles in treating patients with PE. Thus, a multidisciplinary approach to diagnosis, risk stratification, and therapy is required to determine which treatment option is best for a given patient with this complex disease.


Congenital Rhabdomyosarcoma Presenting As A Neck Mass At Birth., L. E. Waldman, A. K. Williamson, J. B. Amodio, L. Collins 2018 Northwell Health

Congenital Rhabdomyosarcoma Presenting As A Neck Mass At Birth., L. E. Waldman, A. K. Williamson, J. B. Amodio, L. Collins

Journal Articles

Rhabdomyosarcoma is a malignant tumor of the soft tissues which preferentially affects the pediatric population. Neonatal rhabdomyosarcoma is rare, and much of the published literature concerning this entity consists of isolated case reports and small case series. Recent work involving the classification of rhabdomyosarcoma has helped to delineate prognostic information based on gene rearrangements. Here, we present a case of congenital rhabdomyosarcoma seen in utero which manifested as a neck mass at birth and was found to harbor a favorable gene fusion.


Transrenal Ureteral Embolization Utilizing Amplatzer Vascular Plugs And N-Butyl Cyanoacrylate Glue., M. X. Jin, A. D. Mohabir, D. M. Caplin, I. Lobko, D. N. Siegel 2018 Zucker School of Medicine at Hofstra/Northwell

Transrenal Ureteral Embolization Utilizing Amplatzer Vascular Plugs And N-Butyl Cyanoacrylate Glue., M. X. Jin, A. D. Mohabir, D. M. Caplin, I. Lobko, D. N. Siegel

Journal Articles

This retrospective study presents three consecutive patients who underwent bilateral ureteral occlusion using the Amplatzer vascular plugs and N-butyl cyanoacrylate glue sandwich method. The patients were 63- and 65-year-old males and a 79-year-old female. Indications for the procedure included severe cystitis and complex vesicular fistulas unresponsive to urinary diversion. All three patients had immediate resolution of urinary leakage, resulting in symptom relief throughout the follow-up period. There were no procedure-related complications or side effects.


Sports Hernia/Athletic Pubalgia Among Women, M. P. Zoland, J. C. Iraci, S. Bharam, L. E. Waldman, J. P. Koulotouros, D. Klein 2018 Northwell Health

Sports Hernia/Athletic Pubalgia Among Women, M. P. Zoland, J. C. Iraci, S. Bharam, L. E. Waldman, J. P. Koulotouros, D. Klein

Journal Articles

© The Author(s) 2018. Background: “Athletic pubalgia,” a term that has gained acceptance over “sports hernia,” is more common in men than women; however, it represents a significant source of morbidity for patients of both sexes. Inconsistent terminology surrounding this entity poses a diagnostic challenge and makes studying the populations at risk difficult. Purpose: To review a case series of women with athletic pubalgia by analyzing their presentations, concomitant pathologies, and surgical outcomes. Study Design: Case series; Level of evidence, 4. Methods: Between 2013 and 2016, 197 patients were seen and evaluated for the diagnosis of athletic pubalgia. Eighteen patients …


A Case Of Primary Squamous Cell Carcinoma Of The Gallbladder With Local Invasion Of The Liver And Peritoneum, And Metastasis To The Omentum., A. C.J. Levy, F. Casalduc-Coca, S. Asiry, A. Goodman 2018 Northwell Health

A Case Of Primary Squamous Cell Carcinoma Of The Gallbladder With Local Invasion Of The Liver And Peritoneum, And Metastasis To The Omentum., A. C.J. Levy, F. Casalduc-Coca, S. Asiry, A. Goodman

Journal Articles

Primary squamous cell carcinoma of the gallbladder is a rare entity that comprises approximately 1%-3% of all primary gallbladder cancers. We report the case of a 37-year-old woman who was diagnosed with a locally invasive squamous cell carcinoma of the gallbladder. Surgical pathology revealed a predominantly squamous cell carcinoma composition of the tumor with a few microscopic foci of adenocarcinoma (


Cost-Effectiveness Of Magnetic Resonance Imaging In Cervical Clearance Of Obtunded Blunt Trauma After A Normal Computed Tomographic Finding, X. Wu, A. Malhotra, B. Geng, V. B. Kalra, K. Abbed, H. P. Forman, P. Sanelli 2018 Zucker School of Medicine at Hofstra/Northwell

Cost-Effectiveness Of Magnetic Resonance Imaging In Cervical Clearance Of Obtunded Blunt Trauma After A Normal Computed Tomographic Finding, X. Wu, A. Malhotra, B. Geng, V. B. Kalra, K. Abbed, H. P. Forman, P. Sanelli

Journal Articles

© 2018 American Medical Association. All rights reserved. IMPORTANCE Magnetic resonance imaging (MRI) continues to be performed for cervical clearance of obtunded blunt trauma, despite poor evidence regarding its utility after a normal computed tomographic (CT) finding. OBJECTIVE To evaluate the utility and cost-effectiveness of MRI vs no follow-up after a normal cervical CT finding in patients with obtunded blunt trauma. DESIGN, SETTING AND PARTICIPANTS This cost-effectiveness analysis evaluated an average patient aged 40 years with blunt trauma from an institutional practice. The analysis used a Markov decision model over a lifetime horizon from a societal perspective with variables from …


Hybrid 3d/2d Convolutional Neural Network For Hemorrhage Evaluation On Head Ct, P. D. Chang, E. Kuoy, J. Grinband, B. D. Weinberg, M. Thompson, R. Homo, J. Chen, H. Abcede, C. G. Filippi, D. Chow, +5 additional authors 2018 Zucker School of Medicine at Hofstra/Northwell

Hybrid 3d/2d Convolutional Neural Network For Hemorrhage Evaluation On Head Ct, P. D. Chang, E. Kuoy, J. Grinband, B. D. Weinberg, M. Thompson, R. Homo, J. Chen, H. Abcede, C. G. Filippi, D. Chow, +5 Additional Authors

Journal Articles

No abstract provided.


Assessment Of The Albumin-Bilirubin (Albi) Grade As A Prognostic Indicator For Hepatocellular Carcinoma Patients Treated With Radioembolization., B. Gui, A. A. Weiner, J. Nosher, S. E. Lu, G. M. Foltz, O. Hasan, S. K. Kim, V. Gendel, N. B. Mani, S. K. Jabbour, +6 additional authors 2018 Zucker School of Medicine at Hofstra/Northwell

Assessment Of The Albumin-Bilirubin (Albi) Grade As A Prognostic Indicator For Hepatocellular Carcinoma Patients Treated With Radioembolization., B. Gui, A. A. Weiner, J. Nosher, S. E. Lu, G. M. Foltz, O. Hasan, S. K. Kim, V. Gendel, N. B. Mani, S. K. Jabbour, +6 Additional Authors

Journal Articles

OBJECTIVE: As the utility of Child-Pugh (C-P) class is limited by the subjectivity of ascites and encephalopathy, we evaluated a previously established objective method, the albumin-bilirubin (ALBI) grade, as a prognosticator for yttrium-90 radioembolization (RE) treatment for patients with hepatocellular carcinoma (HCC).

MATERIALS AND METHODS: A total of 117 patients who received RE for HCC from 2 academic centers were reviewed and stratified by ALBI grade, C-P class, and Barcelona Clinic Liver Cancer stage. The overall survival (OS) according to these 3 criteria was evaluated by Kaplan-Meier survival analysis. The utilities of C-P class and ALBI grade as prognostic indicators …


Structural Parameters Of Mnd Measured By X-Ray Diffraction, Daniel J. Kuiper, Paul Harper 2018 Calvin University

Structural Parameters Of Mnd Measured By X-Ray Diffraction, Daniel J. Kuiper, Paul Harper

Summer Research

In our lungs, there are lipids and lung proteins that work together to allow us to breathe. The proteins are known to encourage non-lamellar phases in lipids, but the function of this property for letting us to breathe is not well understood. The aim of my research was to qualify the behavior of the lipid MNd without any lung protein to allow for a comparison between the effects when formed naturally and when formed with lung protein to give a better understanding of what the protein is doing. Below is a diagram of an MNd molecule. In the presence of …


Osteoid Osteoma: Contemporary Management, Shahryar Noordin, Salim Allana, Kiran Hilal, Riaz Hussain Lukhadwala, Anum Sadruddin Pidani, Nasir Ud Din 2018 Aga Khan University

Osteoid Osteoma: Contemporary Management, Shahryar Noordin, Salim Allana, Kiran Hilal, Riaz Hussain Lukhadwala, Anum Sadruddin Pidani, Nasir Ud Din

Section of Orthopaedic Surgery

Osteoid osteoma is a benign bone-forming tumor with hallmark of tumor cells directly forming mature bone. Osteoid osteoma accounts for around 5% of all bone tumors and 11% of benign bone tumors with a male predilection. It occurs predominantly in long bones of the appendicular skeleton. According to Musculoskeletal Tumor Society staging system for benign tumors, osteoid osteoma is a stage-2 lesion. It is classified based on location as cortical, cancellous, or subperiosteal. Nocturnal pain is the most common symptom that usually responds to salicyclates and non-steroidal anti-inflammatory medications. CT is the modality of choice not only for diagnosis but …


Intra-Arterial Nitroglycerin As Directed Acute Treatment In Experimental Ischemic Stroke, Michael E. Maniskas, Jill M. Roberts, Rebecca Trueman, Annastazia E. Learoyd, Amanda A. Gorman, Justin F. Fraser, Gregory J. Bix 2018 University of Kentucky

Intra-Arterial Nitroglycerin As Directed Acute Treatment In Experimental Ischemic Stroke, Michael E. Maniskas, Jill M. Roberts, Rebecca Trueman, Annastazia E. Learoyd, Amanda A. Gorman, Justin F. Fraser, Gregory J. Bix

Neuroscience Faculty Publications

BACKGROUND: Nitroglycerin (also known as glyceryl trinitrate (GTN)), a vasodilator best known for treatment of ischemic heart disease, has also been investigated for its potential therapeutic benefit in ischemic stroke. The completed Efficacy of Nitric Oxide in Stroke trial suggested that GTN has therapeutic benefit with acute (within 6 hours) transdermal systemic sustained release therapy.

OBJECTIVE: To examine an alternative use of GTN as an acute therapy for ischemic stroke following successful recanalization.

METHODS: We administered GTN IA following transient middle cerebral artery occlusion in mice. Because no standard dose of GTN is available following emergent large vessel occlusion, we …


A Rare Case Of Presacral Epidermoid Cyst In An Adult Male: Emphasis On Diffusion Weighted Magnetic Resonance Sequences In Preoperative Imaging., Muhammad I. Alvi, Fatima Mubarak, Kumail Khandwala, Muhammad Nanish Barakzai, Aisha Memon 2018 Aga Khan University

A Rare Case Of Presacral Epidermoid Cyst In An Adult Male: Emphasis On Diffusion Weighted Magnetic Resonance Sequences In Preoperative Imaging., Muhammad I. Alvi, Fatima Mubarak, Kumail Khandwala, Muhammad Nanish Barakzai, Aisha Memon

Department of Radiology

Epidermoid cyst of the presacral space is a rare congenital lesion of ectodermal origin. Presacral epidermoid cysts have been previously reported in women, however are extremely rare in males. We report a case of presacral epidermoid cyst in a 55-year-old male who presented to our emergency department with acute urinary retention and history of chronic constipation. A non-contrast computed tomography scan was performed with suspicion of urolithiasis, which revealed a well circumscribed low attenuation presacral mass. Magnetic resonance imaging (MRI) of the pelvis was subsequently performed to further characterize the lesion. The mass was returning hypointense T1 and hyperintense T2 …


Motion-Induced Artifact Mitigation And Image Enhancement Strategies For Four-Dimensional Fan-Beam And Cone-Beam Computed Tomography, Matthew J. Riblett 2018 Virginia Commonwealth University

Motion-Induced Artifact Mitigation And Image Enhancement Strategies For Four-Dimensional Fan-Beam And Cone-Beam Computed Tomography, Matthew J. Riblett

Theses and Dissertations

Four dimensional imaging has become part of the standard of care for diagnosing and treating non-small cell lung cancer. In radiotherapy applications 4D fan-beam computed tomography (4D-CT) and 4D cone-beam computed tomography (4D-CBCT) are two advanced imaging modalities that afford clinical practitioners knowledge of the underlying kinematics and structural dynamics of diseased tissues and provide insight into the effects of regular organ motion and the nature of tissue deformation over time. While these imaging techniques can facilitate the use of more targeted radiotherapies, issues surrounding image quality and accuracy currently limit the utility of these images clinically.

The purpose of …


Estimating The Respiratory Lung Motion Model Using Tensor Decomposition On Displacement Vector Field, Kingston Kang 2018 VCU

Estimating The Respiratory Lung Motion Model Using Tensor Decomposition On Displacement Vector Field, Kingston Kang

Theses and Dissertations

Modern big data often emerge as tensors. Standard statistical methods are inadequate to deal with datasets of large volume, high dimensionality, and complex structure. Therefore, it is important to develop algorithms such as low-rank tensor decomposition for data compression, dimensionality reduction, and approximation.

With the advancement in technology, high-dimensional images are becoming ubiquitous in the medical field. In lung radiation therapy, the respiratory motion of the lung introduces variabilities during treatment as the tumor inside the lung is moving, which brings challenges to the precise delivery of radiation to the tumor. Several approaches to quantifying this uncertainty propose using a …


Advances In Dual-Energy Computed Tomography Imaging Of Radiological Properties, Dong Han 2018 Virginia Commonwealth University

Advances In Dual-Energy Computed Tomography Imaging Of Radiological Properties, Dong Han

Theses and Dissertations

Dual-energy computed tomography (DECT) has shown great potential in the reduction of uncertainties of proton ranges and low energy photon cross section estimation used in radiation therapy planning. The work presented herein investigated three contributions for advancing DECT applications. 1) A linear and separable two-parameter DECT, the basis vector model (BVM) was used to estimate proton stopping power. Compared to other nonlinear two-parameter models in the literature, the BVM model shows a comparable accuracy achieved for typical human tissues. This model outperforms other nonlinear models in estimations of linear attenuation coefficients. This is the first study to clearly illustrate the …


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