Tracheostomy Dependance Patterns In Children With 22q11 Deletion Syndrome, 2023 Children's Mercy Kansas City
Tracheostomy Dependance Patterns In Children With 22q11 Deletion Syndrome, Elie Khalifee, Meghan Tracy, Jill M. Arganbright
Research Days
Background: 22q11.2 deletion syndrome (22q11DS) is the most common chromosomal microdeletion syndrome and presentation often includes congenital heart disease (CHD), palate anomalies, and developmental delay. Due to the medical complexity of this syndrome, some patients require tracheostomy. To date, there is little in the literature regarding tracheostomy for these patients.
Objectives/Goal: our aim is to better delineate patients with 22q11DS who require tracheostomy, assess outcomes including decannulation and complications.
Methods/Design: This is a retrospective chart review of patients in our 22q Center’s repository. Inclusion criteria were a diagnosis of 22q11DS with a current or previous history of tracheostomy. Data collected …
Case Report: Vocal Cord Paralysis In The Ed, 2023 Rowan University
Case Report: Vocal Cord Paralysis In The Ed, Richard Baluyot, Russell Mordecai, James Espinosa, Alan Lucerna
Rowan-Virtua Research Day
The incident rate of vocal cord paralysis varies greatly depending on the cause of paralysis as well as if it's unilateral or bilateral, for this poster we will be focusing on unilateral paralysis. From 1985 to 1995 cancer was the primary cause for vocal cord paralysis, however this shifted to primarily iatrogenic surgical injury from 1996 to 2005. In another study it was found that idiopathic paralysis and tumors to both be the primary cause (31.11% respectively), with surgery consisting of 28.89%, and trauma, brain problems, systemic disease and other causes being 2.2%.
Hearing, Cognitive Decline, And The Value Of Hearing Interventions, 2023 Rowan University
Hearing, Cognitive Decline, And The Value Of Hearing Interventions, Lisa M. Price, Jennifer Ren, Victoria Wong Murray, Dylan Trawinski, Ethan Zerpa-Blanco, Sheam Jahan
Rowan-Virtua Research Day
The term “dementia” includes a wide array of diseases. Millions of Americans are affected by these diseases, especially with aging. Its prevalence makes dementia a candidate for exploratory research in understanding its various etiologies and cause-effect relationships in hopes of developing treatment. Numerous studies have been conducted in an attempt to discern whether a causal relationship exists between hearing loss and dementia, as hearing loss frequently precedes dementia. Some publications have reported a correlation between hearing loss treatment and a decreased dementia incidence rate. This review seeks to investigate the associations between hearing loss and dementia, the efficacy of hearing …
Muscle Tension Dysphonia In Singers And Professional Speakers With Ankyloglossia: Impact Of Treatment With Lingual Frenuloplasty And Orofacial Myofunctional Therapy, 2023 The Breathe Institute
Muscle Tension Dysphonia In Singers And Professional Speakers With Ankyloglossia: Impact Of Treatment With Lingual Frenuloplasty And Orofacial Myofunctional Therapy, Isabella Summersgill, Gloria Nguyen, Cullen Grey, Leyli Norouz-Knutsen, Robyn Merkel-Walsh, Christine Katzenmeir, Benjamin Rafii, Soroush Zaghi
International Journal of Orofacial Myology and Myofunctional Therapy
Introduction: Muscle tension dysphonia (MTD) describes a condition affecting the feeling or quality of the voice due to increased muscle tension in and/or around the neck and larynx. Ankyloglossia is a condition of restricted tongue mobility that has been shown to be associated with increased muscle tension. This case series explores outcomes for voice users with MTD who have been treated for ankyloglossia.
Methods: Twelve professional or recreational voice users diagnosed with ankyloglossia were surveyed on their symptoms of MTD before and after treatment with lingual frenuloplasty and pre- and post-operative orofacial myofunctional therapy (OMT), a multidisciplinary approach known as …
Surgical Management Of Velopharyngeal Dysfunction: Major Techniques And Trends For The 21st Century, 2023 Wayne State University School of Medicine
Surgical Management Of Velopharyngeal Dysfunction: Major Techniques And Trends For The 21st Century, Dominic Alessio-Bilowus, Sadaf Hashemian, Kylie Nikolli, Ahmed Hashem Md
Medical Student Research Symposium
INTRODUCTION: Surgical management of velopharyngeal dysfunction (VPD) has become increasingly complex over recent decades with advances in diagnosis, evaluation and technique, and research focus in this area is expected to shift accordingly. This study aims to educate readers on updates in management of VPD and explore changes in surgical methods through the 21st century.
METHODS: A systematic review was conducted of all literature published on surgical treatment of VPD since the year 2000, following PRISMA reporting guidelines. Adult-acquired VPD, any non-surgical management, implants and prosthetic devices, animal or cadaver models, and case series involving less than 10 subjects were excluded. …
Inhibitors Of Histone Deacetylase And Mcl-1 Synergistically Reduce Proliferation In Malignant Melanoma, 2023 Wayne State University School of Medicine
Inhibitors Of Histone Deacetylase And Mcl-1 Synergistically Reduce Proliferation In Malignant Melanoma, Mehrnoosh Ghafouri, Chester Gauss, Yue Xi Phd, William Azkoul Ii Md, Abby Knudsen, Jordan Zuckerman, Sharon K. Michelhaugh Phd, Sandeep Mittal Md, Andrew M. Fribley Phd
Medical Student Research Symposium
Melanoma is a skin cancer that arises in melanocytes; it is the fifth most common cancer in the United States with approximately 100,000 new cases per year. Current treatments for malignant melanoma are surgical excision, radiation therapy and systemic therapy; however, the five-year survival rate for patients with stage IV is 29.8%. There is an urgent unmet clinical need to investigate novel treatments for these patients. Panobinostat is an orally available histone deacetylase inhibitor used in several hematologic malignancies, but it was ineffective as a single agent against melanoma in Phase 1. To address the insufficiency of options for melanoma …
Outcomes Of Dupilumab Treatment In Patients Presenting With Severe Asthma Or Chronic Rhinosinusitis With Nasal Polyps, Over The Age Of 65, 2023 Wayne State University
Outcomes Of Dupilumab Treatment In Patients Presenting With Severe Asthma Or Chronic Rhinosinusitis With Nasal Polyps, Over The Age Of 65, Keisha Arielle Best, Samiat Awosanya, Chandala Chitguppi, Marc Rosen, Mindy Rabinowitz, Elina Toskala, Gurston Nyquist, Jessica Most
Medical Student Research Symposium
Introduction:
Dupilumab is an IL-4/13 inhibitor that has been successfully implemented in the treatment of severe asthma and chronic rhinosinusitis with nasal polyps (CRSwNP). The safety and efficacy of Dupilumab has not been reported for these indications in patients over the age of 65. This study aims to determine the long-term benefits of dupilumab while detailing adverse effects.
Methods:
This study is a single institution retrospective review of patients receiving dupilumab for severe asthma and/or CRSwNP from 2018 to present. Charts were reviewed for patient demographics, Sino-nasal Outcome Test (SNOT-22) scores, asthma control test (ACT) scores, polyp scores, and adverse …
Otologic Manifestations In The Setting Of Seronegative Small Vessel Vasculitis: A Case Report, 2023 Thomas Jefferson University
Otologic Manifestations In The Setting Of Seronegative Small Vessel Vasculitis: A Case Report, Kathleen Gillmore, Samiat Awosanya, Ayan Kumar, Catherine Teskin, Rebecca Chiffer
Student Papers, Posters & Projects
Some patients with autoimmune disease will experience otologic symptoms, such as pain and hearing loss. We present a patient with ANCA-associated vasculitis who required surgery for a suspicious mastoid lesion associated with her disease.
International Consensus Statement On Allergy And Rhinology: Allergic Rhinitis – 2023, 2023 The University of Texas Rio Grande Valley
International Consensus Statement On Allergy And Rhinology: Allergic Rhinitis – 2023, Sarah K. Wise, Cecelia C. Damask, Lauren T. Roland, Charles Ebert, Joshua M. Levy, Sandra Lin, Amber Luong, Kenneth Rodriguez, Ahmad R. Sedaghat, Helene J. Krouse
School of Medicine Publications and Presentations
Background
In the 5 years that have passed since the publication of the 2018 International Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (ICAR-Allergic Rhinitis 2018), the literature has expanded substantially. The ICAR-Allergic Rhinitis 2023 update presents 144 individual topics on allergic rhinitis (AR), expanded by over 40 topics from the 2018 document. Originally presented topics from 2018 have also been reviewed and updated. The executive summary highlights key evidence-based findings and recommendation from the full document.
Methods
ICAR-Allergic Rhinitis 2023 employed established evidence-based review with recommendation (EBRR) methodology to individually evaluate each topic. Stepwise iterative peer review and consensus …
International Consensus Statement On Allergy And Rhinology: Allergic Rhinitis – 2023, 2023 The University of Texas Rio Grande Valley
International Consensus Statement On Allergy And Rhinology: Allergic Rhinitis – 2023, Sarah K. Wise, Cecelia C. Damask, Lauren T. Roland, Charles Ebert, Joshua M. Levy, Sandra Lin, Amber Luong, Kenneth Rodriguez, Ahmad R. Sedaghat, Helene J. Krouse
School of Medicine Publications and Presentations
Background
In the 5 years that have passed since the publication of the 2018 International Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (ICAR-Allergic Rhinitis 2018), the literature has expanded substantially. The ICAR-Allergic Rhinitis 2023 update presents 144 individual topics on allergic rhinitis (AR), expanded by over 40 topics from the 2018 document. Originally presented topics from 2018 have also been reviewed and updated. The executive summary highlights key evidence-based findings and recommendation from the full document.
Methods
ICAR-Allergic Rhinitis 2023 employed established evidence-based review with recommendation (EBRR) methodology to individually evaluate each topic. Stepwise iterative peer review and consensus …
Molecular Diagnostics In The Evaluation Of Thyroid Nodules: Current Use And Prospective Opportunities, 2023 Thomas Jefferson University
Molecular Diagnostics In The Evaluation Of Thyroid Nodules: Current Use And Prospective Opportunities, Jena Patel, Joshua Klopper, Elizabeth E. Cottrill
Department of Otolaryngology - Head and Neck Surgery Faculty Papers
Thyroid cancer is the most common endocrine malignancy with an estimated 43,800 new cases to be diagnosed in 2022 and representing the 7th most common cancer in women. While thyroid nodules are very common, being identified in over 60% of randomly selected adults, only 5-15% of thyroid nodules harbor thyroid malignancy. Therefore, it is incumbent upon physicians to detect and treat thyroid malignancies as is clinically appropriate and avoid unnecessary invasive procedures in patients with benign asymptomatic lesions. Over the last 15-20 years, rapid advances have been made in cytomolecular testing to aid in thyroid nodule management. Initially, indeterminate thyroid …
Rare Case Of Nasal Vault Oncocytic Cystadenoma, 2023 Thomas Jefferson University
Rare Case Of Nasal Vault Oncocytic Cystadenoma, Aarti Agarwal, Kathleen Mcclain, Karen Banker, Kudakwashe Chikwava, Udayan K. Shah
Department of Otolaryngology - Head and Neck Surgery Faculty Papers
Background: Oncocytic Cystadenomas are a rare benign pathology often found to arise from the salivary glands, reported more commonly in minor salivary glands, but even more rarely in major salivary glands and the larynx. This is the first known report of a nasal vault oncocytic cystadenoma in a pediatric patient.
Methods: Case Report and Literature Review.
Case presentation: A 10-year-old female presented with a mass involving the left nasal vestibule that caused nasal obstruction and a visible external abnormality. MRI imaging revealed a cystic lesion in the anterior nasal cavity that was rim enhancing with a bright T2 signal that …
Direct Transnasal Dural Suturing After Endoscopic Hypophysectomy: Promising Outcomes, 2023 Departments of Neurosurgery
Direct Transnasal Dural Suturing After Endoscopic Hypophysectomy: Promising Outcomes, Ahmed Abdelwahab, Abdelwahab Rakha, Mohammed Abdelwab, Yasser Khfagy, Hossam Elsisi
Pan Arab Journal of Rhinology
Background Endoscopic endonasal transsphenoidal surgery is the gold standard method for surgical management of pituitary adenomas; yet the troublesome issue is the potential of cerebrospinal fluid (CSF) leak with possible persistent leak and meningitis. Sellar reconstruction is a prerequisite to prevent postoperative CSF leak. Watertight dural stitching is a reliable method of closure of intraoperative defects, but this was always challenging due to the narrow and deep operative field and the need of special designs of surgical instruments. We present a simple, easy to use direct dural suture with no need to additional surgical instrument for closure of dural tear …
Modified Posterior Nasal Nerve Neurectomy With Inferior Turbinoplasty, As A Treatment For Intractable Rhinitis Syndrome: A Long-Term Effect Prospective Cohort Study, 2023 Department of OtoRhinoLaryngology, Banha University, Banha
Modified Posterior Nasal Nerve Neurectomy With Inferior Turbinoplasty, As A Treatment For Intractable Rhinitis Syndrome: A Long-Term Effect Prospective Cohort Study, Ahmed S. El Sayed Eid Saleh, Hossam M. Kamal Aly Rabie, Tarek A.H. Hamdy
Pan Arab Journal of Rhinology
Background Allergic and vasomotor rhinitis are a well-known medical entities affecting a huge population. In most cases, medical therapy helps these people. However, sometimes these treatments are often ineffective. The surgical treatment of intractable rhinitis had been introduced a long time ago, starting from vidian nerve neurectomy to a recently introduced more simple and safe procedure [endoscopic posterior nasal nerve (PNN) neurectomy]. This study combined two valid and widely used surgical procedures for intractable rhinitis surgical management, that is, modified PNN neurectomy and inferior turbinoplasty (IT), aiming to ensure long-term results. Patients and methods A total of 30 adult patients …
Dilemma Of Prolonged Post- Covid 19 Anosmia Treatment, 2023 Department(s) and institution(s) otorhinolaryngology depertment, faculty of medicine, Assiut university
Dilemma Of Prolonged Post- Covid 19 Anosmia Treatment, Abdelhakeem Mahmoud Ali Ragaee
Pan Arab Journal of Rhinology
Context: Anosmia is one of the pathognomonic neurological symptoms of COVID-19 since its begging at the end of 2019. Many patients suffered persistently for prolonged time after infected with this virus. Aims: The aim of this study was to recognise the predisposing factors, to identify possible treatment regimens and to assess the prognosis of prolonged post- COVID-19 anosmia. Settings and Design: retrospective observational study
Methods and Material: study conducted among patients with post COVID-19 anosmia. Thirty-four patients sought medical advice for having prolonged post-COVID-19 anosmia between the period of August 2020 and October 2021 and assessed for predisposing factors. They …
Benefits Of Vitamin D Supplementation After Functional Endoscopic Sinus Surgery For Recurrent Nasal Polyposis, 2023 Department of Otorhinolaryngology, El-Hussein University Hospital, Al-Azhar University, Cairo, Egypt
Benefits Of Vitamin D Supplementation After Functional Endoscopic Sinus Surgery For Recurrent Nasal Polyposis, Mohammad A. Al-Morsy, Marawan A. Ibrahim
Pan Arab Journal of Rhinology
Background Nasal polyps as a type of nasal masses usually present with nasal obstruction and smell disorders. There is high recurrence following sinus surgery, which motivated us to study the role of cholecalciferol in preventing recurrence of sinonasal polyposis after endoscopic excision of these polyps. Objective The aim of the work was to study the clinical and radiological outcomes of oral cholecalciferol supplementation after functional endoscopic sinus surgery for recurrent nasal polyposis. Patients and methods A total of 62 patients with recurrent sinonasal polyposis were included in our study during the period from January 2019 to May 2022. The patients …
Effect Of Tonsillectomy On Humoral Immunity In Children With Obstructive Sleep Apnea Below The Age Of 3 Years, 2023 Department of Otorhinolaryngology, Faculty of Medicine, Benha University, Benha, Egypt
Effect Of Tonsillectomy On Humoral Immunity In Children With Obstructive Sleep Apnea Below The Age Of 3 Years, Ayman A. Mohamdy, Mohammed F. , Shendy, Nahed F. Khater, Mostafa Gomaa Sobhy
Pan Arab Journal of Rhinology
Background
Tonsils are one of the most significant secondary lymphoid organs in immune system. They contain B and T lymphocytes. B cells produce all five classes of immunoglobulins. The tonsillectomy’s effect on the immune system is still up for debate.
Objective
The study was done to observe the effect of tonsillectomy on humoral immunity parameters (IgA, IgM, and IgG) in children with obstructive sleep apnea before and after tonsillectomy.
Patients and methods
A total of 60 patients who were scheduled for tonsillectomy because of obstructive sleep apnea, with ages below 3 years, and diagnosed by clinical findings of adenotonsillar hypertrophy …
Acute-Phase Reactants Association With Smell Disorders In Coronavirus Disease 2019-Infected Patients, 2023 Department of Otolaryngology, Faculty of Medicine, Cairo University, Cairo, Egypt
Acute-Phase Reactants Association With Smell Disorders In Coronavirus Disease 2019-Infected Patients, Ahmed A. Nassar, Ahmad M. Eltelety
Pan Arab Journal of Rhinology
Objective Olfaction is a complex sensory process that has not been fully investigated. In this study, we aimed at investigating whether there is an association between acute-phase reactants [C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), neutrophil-to-lymphocyte ratio (NLR), and serum ferritin] and the presence of smell disorders in coronavirus disease 2019-infected patients. Patients and methods A prospective study was conducted on 61 patients presented to the Otolaryngology Department with a confirmed diagnosis of coronavirus disease 2019 based on the real-time reverse transcription PCR between July 2020 and February 2021. Participants in this study were divided into two groups: group A …
Aberrant Expression Of Soluble Programmed Death-Ligand 1 And Inducible Costimulator Ligand In Patients With Nasal Polyps, 2023 Departments of Otorhinolaryngology & Head and Neck Surgery
Aberrant Expression Of Soluble Programmed Death-Ligand 1 And Inducible Costimulator Ligand In Patients With Nasal Polyps, Mohamed M. Osmana, Omnia H.B. El-Badaway, Asmaa M. Zahran, Mohamed A.M. Salem, Ahmed G. Abdelraheemd
Pan Arab Journal of Rhinology
Aim We aimed to measure the levels of soluble programmed death-ligand 1 (sPD-L1) and soluble inducible costimulator ligand (sICOS-L) in patients with nasal polyps and to compare their levels between a group with allergic rhinitis (AR) with nasal polyps and another with allergic fungal rhinosinusitis (AFRS). The study also aimed to assess the relationship between their levels and disease severity. Patients and methods The study included 35 patients admitted for endoscopic sinus surgery for nasal polyps, who were divided into 17 with AR and 18 with AFRS and 20 controls. Radiologic computed tomography (CT) score of Lund-Mackay was used to …
Outcomes Of Middle Turbinate-Septal Adhesion Technique And Trans-Septal Middle Turbinate Suture Technique To Prevent Middle Turbinate Lateralization: A Comparative Study, 2023 Unit of Otorhinolaryngology–Head & Neck Surgery, Department of Surgery, University of Sulaimani, College of Medicine, Sulaymaniyah Teaching Hospital, Sulaymaniyah, Kurdistan Region, Iraq
Outcomes Of Middle Turbinate-Septal Adhesion Technique And Trans-Septal Middle Turbinate Suture Technique To Prevent Middle Turbinate Lateralization: A Comparative Study, Muaid I. Aziz Baban, Hiwa A. Rawandizi, Hozan F. Ali, Sahar J. Hadi, Shkar N. Mohammed
Pan Arab Journal of Rhinology
Background Middle turbinate lateralization (MTL) is the most common undesirable sequela after functional endoscopic sinus surgery (FESS), which can result in recurrent sinusitis. Objectives To examine the efficacy and outcomes of different techniques to prevent failure of the primary surgery. Patients and methods Eighty patients who presented with chronic rhinosinusitis listed for FESS were enrolled in this study. Patients were divided randomly into two groups, with 40 patients each. In group A, middle turbinate (MT) was stabilized by adhesion technique, and in group B, MT was stabilized via suture technique. A comparison of the effectiveness and the outcomes of both …