A Case-Control Comparison Of Alopecia Areata And Inflammatory Bowel Disease,
2025
HCA Healthcare
A Case-Control Comparison Of Alopecia Areata And Inflammatory Bowel Disease, Mohammad Fardos, Amritpal Kooner, Rawle A. Sekhon, Beniamin Zeka, Aditya Dutt, Richard Miller
West Florida Division GME Research Day 2025
No abstract provided.
Adult-Onset Iga Vasculitis And Nephropathy In Alcoholic Cirrhosis: A Case Report And Brief Review,
2025
HCA Healthcare
Adult-Onset Iga Vasculitis And Nephropathy In Alcoholic Cirrhosis: A Case Report And Brief Review, Brett Thomas, Summer Wong, Walaa Abualhuda, Siddhi Patodia, Elaine Bruno, David Esguerra, Richard Miller
West Florida Division GME Research Day 2025
No abstract provided.
Inked And Infected: A Case That Highlights The Emerging Concern Of Tattoo-Associated Mycobacterium Abscessus,
2025
HCA Healthcare
Inked And Infected: A Case That Highlights The Emerging Concern Of Tattoo-Associated Mycobacterium Abscessus, Tory Starzyk, Neena Edupuganti
West Florida Division GME Research Day 2025
No abstract provided.
Man With An Itchy Back,
2025
Macon & Joan Brock Virginia Health Sciences at Old Dominion University
Man With An Itchy Back, Katherine Schaffer, Nevin Adamski, Brittany Ambrose, Kathleen Anderson
Department of Emergency Medicine Faculty Publications
[First paragraph] A 61-year old man with no significant past medical history presented with painful bug bites on his lower back 1 day after a 1.5-week-long visit to Africa. He noticed bug bites on his lower back 3 days ago; since then, they have increased in size and become more painful. He was prescribed doxycycline at urgent care earlier that morning and had taken 1 dose. He is taking prophylactic medications for malaria and has had no fever at home. Vital signs, exquisitely tender papular lesions with a central punctum and surrounding erythema in the bilateral paralumbar regions.
Assessment Of Primary Malignancy Risk Following Initiation Of Biologic Therapy In Psoriasis Patients,
2025
Macon & Joan Brock Virginia Health Sciences at Old Dominion University
Assessment Of Primary Malignancy Risk Following Initiation Of Biologic Therapy In Psoriasis Patients, Chunghwan Ro, Ana Ormaza Vera, Waleed Adawi, Alexander Yap, Clinton W. Enos
Department Dermatology Faculty Publications
Limited evidence exists regarding the long-term oncologic safety of biologic therapies, particularly interleukin (IL)-17 inhibitors (IL-17i) and IL-23i, in the management of psoriasis. This propensity-score-matched retrospective-cohort study assessed the risk of developing a primary malignancy within 10-years following exposure to an FDA-approved biologic among psoriasis patients compared to biologic-naïve controls. After propensity-score-matching, 32,230 biologic-exposed patients were further grouped into cohorts of tumor necrosis factor inhibitors (TNFi, n=16,011), IL-23i (n=5,604), IL-12/23i (n=3,856), and IL-17i (n=5,467). During a 10-year period, TNFi-treated patients had a reduced risk of developing any primary malignancy compared to biologic-naïve psoriasis patients [HR 0.80(0.73-0.87)]. Similarly, a lower incidence …
Decoding Tattoo And Permanent Makeup Pigments: Linking Physicochemical Properties To Absorption, Distribution, Metabolism, And Elimination Profiles Using Quantitative Structure-Activity Relationship (Qsar)-Based New Approach Methodologies (Nams),
2025
Bharati Vidyapeeth (deemed to be) University
Decoding Tattoo And Permanent Makeup Pigments: Linking Physicochemical Properties To Absorption, Distribution, Metabolism, And Elimination Profiles Using Quantitative Structure-Activity Relationship (Qsar)-Based New Approach Methodologies (Nams), Girija Bansod, Ajay Vikram Singh, Preeti Bhardwaj, Tulika Rai, Sweta Vijay Nakhale, Amruta Shelar, Rajendra Patil, Peter Laux, Andreas Luch, Christopher J. Osgood, Michael W. Stacey
Biological Sciences Faculty Publications
The safety and quality of tattoo and permanent makeup (PMU) pigments are subject to increased scrutiny due to their potential to cause adverse effects like anaphylaxis, photoallergic responses, and long-term toxicity. These undesirable reactions governed by their chemical structure possess varied physicochemical properties and absorption, distribution, metabolism, and elimination (ADME) characteristics. These properties control the pigment behavior during application, stability, and interaction with human tissue. The correlation between these physicochemical characteristics and ADME parameters of tattoo/PMU pigments remain under-explored despite the current advances in toxicology. Our study aims to address and bridge the gap by leveraging open-access QSAR computational toxicology …
The Quality-Of-Life Benefits And Risk Of Isotretinoin (Accutane) In Acne Treatment: A Systematic Review,
2025
University of Central Florida
The Quality-Of-Life Benefits And Risk Of Isotretinoin (Accutane) In Acne Treatment: A Systematic Review, Noelia Valencia Zuniga
Honors Undergraduate Theses
Acne vulgaris is a prevalent dermatological condition, particularly affecting adolescents and young adults. While often treated as a cosmetic issue, acne can significantly impair a patient's mental health and overall quality of life (QoL). Isotretinoin, commonly known as Accutane, is widely regarded as the most effective treatment for severe and persistent acne. However, its use is controversial due to a range of potential side effects, including psychiatric symptoms, teratogenicity, and other systemic complications. To better understand the risk-benefit profile of isotretinoin in acne treatment, we conducted a systematic review, focusing on the QoL benefits and risks associated with its use. …
Cutaneous Cytomegalovirus In Mixed Serostatus Kidney Transplant Patient,
2025
Thomas Jefferson University
Cutaneous Cytomegalovirus In Mixed Serostatus Kidney Transplant Patient, Dominic Finan, Vaibhav Garg, Lucjan Lang, Tricia Royer, Katherine Belden, Sherry Yang
Department of Dermatology and Cutaneous Biology Faculty Papers
Cutaneous cytomegalovirus infection is a rare but serious complication in solid organ transplant recipients. We present a 47-year-old male kidney transplant recipient with a chronic, nonhealing right lower extremity ulcer. Initial biopsies revealed septic vasculopathy, leading to treatment with sodium thiosulfate and antibiotics for suspected calciphylaxis. Despite regular wound care, the ulcer continued to worsen. After completing 6 months of cytomegalovirus prophylaxis, surveillance viral levels remained undetectable, but the ulcer progressed considerably. Worsening severity prompted hospitalization, during which cytomegalovirus viremia was detected, and an ulcer biopsy confirmed cytomegalovirus inclusion bodies. Antiviral therapy was reinitiated, resulting in rapid and sustained wound …
Inpatient Dermatology Vignettes: Seborrheic Dermatitis,
2025
HCA Healthcare
Inpatient Dermatology Vignettes: Seborrheic Dermatitis, Garrett Furth, Henry Lim, Marshall Hall, Christian Scheufele, Michael Carletti, Stephen Weis
North Texas Research Forum 2025
Seborrheic dermatitis is a common inflammatory disorder characterized by greasy scale, itching, and erythema. It commonly affects areas of the skin that have high sebum production or are sebaceous gland-rich, including the scalp, face, sternum, axilla, groin, and other skin folds. Seborrheic dermatitis can present in infants, adolescents, and adults, and is more common in men. The etiology is not fully understood, but contributing factors include presence of the yeast genus Malassezia, androgen levels, immunosuppression, family history, and stress or lack of sleep. Interestingly, those with neurological and psychiatric conditions, including Parkinsons Disease, spinal cord injury, epilepsy, and tardive dyskinesia, …
Perceived Risk Of Skin Cancer: Influence Of Family History, Age, Ethnicity, And Fitzpatrick Type,
2025
HCA Healthcare
Perceived Risk Of Skin Cancer: Influence Of Family History, Age, Ethnicity, And Fitzpatrick Type, Henry Lim, Reem Ayoub, Rafael Do Valle, Kristina Kafle, Dana Olsen, Ysabelle Martinez, Christina Guo, Marshall Hall, Christian Scheufele, Michael Carletti, Stephen Weis
North Texas Research Forum 2025
Background: Skin cancer in the United States accounts for approximately 50% of new early cancer diagnoses. Despite this, many individuals underestimate their personal risk, leading to lower engagement in preventative behaviors. Several factors may influence an individual’s perceived risk, including family history, age, race, ethnicity, skin type, and gender. While some individuals recognize their increased susceptibility based on personal, familial, and cultural experiences, others may have a lower perceived risk due to misconceptions or limited awareness. This study examines how these demographic factors influence individuals' perceived risk of skin cancer. Methods: This study analyzed data from 333 individuals aged 19 …
Follicular Occlusion Syndrome: Diagnosis, Management, And Emerging Insights,
2025
HCA Healthcare
Follicular Occlusion Syndrome: Diagnosis, Management, And Emerging Insights, Henry Lim, Reem Ayoub, Rafael Do Valle, Marshall Hall, Michael Carletti, Stephen Weis
North Texas Research Forum 2025
Follicular Occlusion Syndromes (FOS) are rare chronic relapsing skin disorders characterized by abnormal follicular hyperkeratinization, plugging, and inflammation. FOS are more commonly discussed as a ‘triad’ or ‘tetrad’ based on the patient’s clinical presentation. The triad includes hidradenitis suppurativa, acne conglobata, and dissecting cellulitis of the scalp. The tetrad in addition to the triad includes a history of pilonidal cysts. These disorders have a considerably negative effect on quality of life due to chronic pain, psychological distress, and body image concerns. Delayed or misdiagnosis can exacerbate patient outcomes, heightening the importance of timely identification and multidisciplinary treatment. We present two …
Body Dysmorphic Disorder Presenting As Alopecia Anxiety: A Case Report,
2025
HCA Healthcare
Body Dysmorphic Disorder Presenting As Alopecia Anxiety: A Case Report, Henry Lim, Paige Loux, Arianne Felicitas, Marshall Hall, Christian Scheufele, Garrett Furth, Michael Carletti, Stephen Weis
North Texas Research Forum 2025
Background: Body dysmorphic disorder (BDD) involves a preoccupation with a nonexistent or insignificant physical defect that causes clinically significant distress and impacts a patient's daily functioning. We present a case of a patient with body dysmorphia that manifested as anxiety about hair loss. Case Information: A 48-year-old otherwise healthy female presented to the dermatology clinic with the chief complaint of 8 months of hair loss. She had been seen previously by 2 other dermatologists. She brought 28 pages of paperwork to her first appointment detailing previous work-up, including four separate skin punch biopsies consistent with androgenetic, non-cicatricial (non-scarring) alopecia. Other …
Skin Color Cannot Be Confined To Six Categories: Comparing The Fitzpatrick Scale And Colorimetric Measures,
2025
HCA Healthcare
Skin Color Cannot Be Confined To Six Categories: Comparing The Fitzpatrick Scale And Colorimetric Measures, Henry Lim, Kristina Kafle, Reem Ayoub, Dana Olsen, Ysabelle Martinez, Rafael Do Valle, Christina Guo, Marshall Hall, Christian Scheufele, Michael Carletti, Stephen E. Weis
North Texas Research Forum 2025
Purpose The Fitzpatrick Scale (FS), originally developed to dose photochemotherapy in Caucasian skin, has become widely adopted for skin color categorization. It originally included types I-IV, with types V-VI added later for darker skin. The FS was designed for UV radiation reactivity assessment. However, it is increasingly used as a proxy for objective skin color classification, despite being based on a subjective questionnaire. Individual Typology Angle (ITA), a validated colorimetric measurement, presents a potential alternative. Previous studies examining these classification systems have been limited by small sample sizes and uneven distribution across skin tones with subjects predominantly having lighter skin …
An Unusual Case Of Indolent Systemic Mastocytosis: Diagnostic Insights In The Absence Of Classic Systemic Symptoms,
2025
HCA Healthcare
An Unusual Case Of Indolent Systemic Mastocytosis: Diagnostic Insights In The Absence Of Classic Systemic Symptoms, Henry Lim, Jonah Gutierrez, Rafael Do Valle, Reem Ayoub, Marshall Hall, Christian Scheufele, Garrett Furth, Michael Carletti, Stephen Weis
North Texas Research Forum 2025
Introduction: Mastocytosis is a disorder characterized by an abnormal clonal accumulation and subsequent activation of mast cells within one or more organs. It is generally classified as either cutaneous, with or without systemic involvement, or systemic without cutaneous disease based on major and minor criterion. Indolent systemic mastocytosis (ISM) is a subclass of systemic mastocytosis with generally good prognosis. While the etiology of ISM is not completely understood, those who are affected typically have the KIT D816V mast cell receptor mutation. Given that ISM is mast cell mediated, patients predominantly present with a wide range of symptoms related to mast …
Current Trends In School Nursing For Diabetes & Dermatology,
2025
HCA Healthcare
Current Trends In School Nursing For Diabetes & Dermatology, Ali Al-Nahi, Jeffrey Dickerson, Enith Espinosa Palmett, Shterna Frand, Garrett Furth, Matthew Gutzmer, Marshall Hall, Sana Khan, Shana-Kay Lambert-Johnson, Henry Lim, Kelly Mofor, Lakshmi Morla, Ali Nazim, Rui Zhang, Christian Scheufele, Zara Soomro, Michele Mccarroll, Taylor Pickering, Jasmine Silva, Brina Gonzalez, Devika Adusumilli, Sherri Morgan, Nischal Pokhrel
North Texas Research Forum 2025
Background: School nurses are on the front lines of assessing, identifying and treating school-age children with a number of health complications. Implementing nursing services in schools has previously demonstrated improved medical care costs for students, less productivity loss for parents, and less productivity loss for teachers. As a result, nursing services in schools provide a cost-beneficial investment of public money, and warrant both financial support from policy makers as well as educational support from local healthcare services. Aim Statement: This quality improvement project addressed the targeted continuing education gap topics of Dermatology and Diabetes management in school age children. Methods: …
A Case Of Neutrophilic Dermatosis Of The Dorsal Hands With Post-Traumatic Onset,
2025
HCA Healthcare
A Case Of Neutrophilic Dermatosis Of The Dorsal Hands With Post-Traumatic Onset, Marshall Hall, Kristina Kafle, Henry Lim, Christian Scheufele, Garrett Furth, Michael Carletti, Stephen Weis
North Texas Research Forum 2025
Background Sweet Syndrome is an acute, febrile neutrophilic dermatosis that is characterized by painful red lesions, fever, and neutrophilia with histological findings of dermal neutrophilic infiltrate. Neutrophilic Dermatosis of the Dorsal Hands is a localized variant of Sweet Syndrome. Neutrophilic Dermatosis of the Dorsal Hands presents with focused lesions on the dorsal hands, most commonly between the index finger and thumb, typically with fewer systemic manifestations. This condition presents significant diagnostic challenges as it can mimic infectious processes, potentially leading to delayed appropriate treatment. Case Information A 64-year-old male presented to the emergency department with wounds on the bilateral hands. …
Investigating The Relationship Between Skin Color, Ethnicity, And The Fitzpatrick Skin Scale,
2025
HCA Healthcare
Investigating The Relationship Between Skin Color, Ethnicity, And The Fitzpatrick Skin Scale, Henry Lim, Dana Olsen, Reem Ayoub, Maria Francesca Ysabelle Martinez, Rafael Do Valle, Kristina Kafle, Christina Guo, Marshall Hall, Christian Scheufele, Michael Carletti, Stephen Weis
North Texas Research Forum 2025
Introduction: The Fitzpatrick skin scale has long been used as a proxy for skin tone categorization. However, its initial creation was to classify reactivity of white skin to ultraviolet A radiation. A reported one-third of dermatologists conflate the Fitzpatrick skin scale for race and ethnicity. Approximately half of the dermatologists also reported utilizing the Fitzpatrick scale to describe skin color. The goal of this study was to compare the Fitzpatrick scale to skin color and ethnicity in a larger, cohort including the full spectrum of skin tones. Methods: Subjects completed a standardized questionnaire. The questionnaire encompassed subjective classification methods: self-reported …
A Case Of Biopsy-Proven Atopic Dermatitis Perpetuated By Psychosomatic Factors,
2025
HCA Healthcare
A Case Of Biopsy-Proven Atopic Dermatitis Perpetuated By Psychosomatic Factors, Henry Lim, Jamie Y. Choe, Marshall Hall, Arianne Felicitas, Christian Scheufele, Garrett Furth, Michael Carletti, Stephen Weis
North Texas Research Forum 2025
Introduction: Psychodermatology is an interdisciplinary branch of psychosomatic medicine that addresses interactions between the psyche and skin. Stress is often a key exacerbating factor and highlights the bidirectional relationship between psychological factors and skin disorders. Atopic dermatitis (AD) is a chronic skin condition affecting pediatric and adult populations with an estimated global prevalence of approximately 2.6%, or approximately 204 million people. AD classically presents with a red, scaly, pruritic rash. Here, we present a case of biopsy-proven AD induced by stress-associated behaviors related to patient-identified obsessive-compulsive habits. Case Presentation: A 61-year-old female presented for persistent itching and white discoloration in …
Molluscum Dermatitis In A Pediatric Patient,
2025
HCA Healthcare
Molluscum Dermatitis In A Pediatric Patient, Garrett Furth, Olivia Mayer, Marshall Hall, Henry Lim, Christian Scheufele, Michael Carletti, Stephen Weis
North Texas Research Forum 2025
Atopic dermatitis (AD) is a chronic relapsing condition characterized by irritation, redness, inflammation, and itching of the skin. The cause of AD is theorized to be multifactorial, including genetic components, such as mutations in filaggrin, environmental exposures, and immune predisposition. AD often presents in childhood and adolescence, but can appear at any age. AD eruptions arise through various triggers, which commonly include soaps, detergents, fabrics, and cold or hot weather. Importantly, viral infections can also serve as a trigger, causing systemic inflammation via host defense mechanisms. Molluscum contagiosum (MC) is a double-stranded DNA virus that classically manifests as small, dome-shaped, …
Clinical Evaluation And Management Of Terra Firma-Forme Dermatosis: Insights From Two Diverse Cases,
2025
HCA Healthcare
Clinical Evaluation And Management Of Terra Firma-Forme Dermatosis: Insights From Two Diverse Cases, Henry Lim, Rafael Do Valle, Reem Ayoub, Marshall Hall, Michael Carletti, Stephen Weis
North Texas Research Forum 2025
Terra Firma-Forme Dermatosis (TFFD), also known as Duncan’s dirty dermatosis is a benign, asymptomatic dermatologic condition characterized by well-demarcated brown patches to hyperkeratotic papules or plaques. It most commonly affects the neck, trunk, and face but can appear on other body regions. A key diagnostic feature is that these lesions persist despite routine washing with soap and water but can be removed by forcibly wiping the affected area with 70% isopropyl alcohol, revealing normal underlying skin. The exact etiology of TFFD remains unknown, though it is thought to involve abnormal keratinization or delayed desquamation. This condition is often underdiagnosed or …
