Optimization Of Prosthetic Hands: Utilizing Modularity To Improve Grip Force, Grasp, And Versatility, Jordan William Harris

UNLV Theses, Dissertations, Professional Papers, and Capstones

It has been demonstrated that although many varieties of upper limb prosthetics exist, commercially available prosthetics are outdated and unsatisfactory. Ineffectiveness and limitations have led to some prosthesis wearers having to own multiple devices, whereas others have given up on them entirely. Even though ample research has been conducted to design and test new hand designs, the industry appears to rest in an overall stagnated state.

It was proposed here, that one problem with prosthetic research is an excess of variables involved in testing, and therefore the improper application of the scientific method. It seems that each time a research …

The Effect Of Bone And Ligament Morphology Of Ankle Joint Loading In The Neutral Position, Jinhyuk Kim

Mechanical & Aerospace Engineering Theses & Dissertations

Computational modeling of joints is used to investigate the effect of injuries, to plan surgeries, and to answer questions about joints that cannot be answered experimentally. Existing models of the ankle joint are moving toward being able to model specific patients, however, they do not include all of the anatomy (e.g., bones and/or ligaments) and have restrictive boundary conditions. These simplification in anatomy are made to minimize pre-processing and computation time. Because biomechanical modeling is increasingly focused on the implementation of patient specific cases, the effects of including more anatomical structures and determining how they affect the model results is …

Self-Powered Ankle Prosthetic, Corina M. Espelien, Kelsey Pietzsch, Anna Sullivan

Mechanical Engineering

Originating from QL+'s customer requirements, the main technical specifications were to have 80% physiological range of motion, elastic energy return, impact absorption, and no external power sources. Based on the background research conducted and the discussions with experts in the field, the project team decided to focus on designing a prosthetic that focused on plantarflexion and dorsiflexion for a more comfortable gait. The main components of the final design are a hydraulic shock absorber, cam, torsion springs, heel, stopper, and separated keel. The heel, front and back keels, and stopper were manufactured out of carbon fiber. The link, lever, attachment …

A Computational Fluid Dynamics Study On Bidirectional Glenn Shunt Flow With An Additional Pulsatile Flow Through A Modified Blalock-Taussig Shunt, Seda Aslan

LSU New Orleans Theses and Dissertations

The blood flow through the Bidirectional Glenn shunt (BGS) and modified Blalock-Taussig shunt (mBTS) to the pulmonary arteries (PAs) was analyzed using Computational Fluid Dynamics. This study consisted of the steady and pulsatile cases. In case one, the results of blood flow through the BGS for the Newtonian and non-Newtonian viscosity models were compared. Case two focused on having an additional pulsatile blood flow through the mBTS using the non-Newtonian Carreau viscosity model. The geometries were created based on the angiograms. In case one, boundary conditions to be specified at the inlets were obtained from the flow rate measurements via …

Development And Evaluation Of A Biocompatible Electroactive Sensor For Continuous Blood Pressure Measurement., Scott D. Cambron

Electronic Theses and Dissertations

Piezo-active composites have been implemented for sensing and transduction for decades. The 0-3 ceramic/polymer composite is one of the most common composite types used for sensing applications, owing to their tailorable properties of the two-phase composition, consisting of a three-dimensionally connected polymer/rubber matrix (inactive phase) with a dispersion of isolated piezo-ceramic particles (active phase). This thesis describes a method to develop novel biocompatible perivascular band comprised of a two-phase piezo-active composite to be fabricated using simple manufacturing processes. Biomaterials such as tissue scaffolds comprised of silk fibroin (SF) and chitosan (CS), and biocompatible soft rubbers will be implemented as the …

Design And Validation Of An In Vivo Long-Term Attachment Capsule Robot, Wanchuan Xie

Department of Mechanical and Materials Engineering: Dissertations, Theses, and Student Research

The invention of capsule endoscopy (CE) made the non-invasive monitoring of the entire small bowel possible and became the primary means for diagnosing small bowel pathology. In the last decade, capsule robots have been transformed from diagnostic devices into a widely studied biomedical platform with the potential for active locomotion, drug delivery and therapeutic capabilities. To perform accurate on-site drug release and therapy, it is necessary for a capsule robot to be able to attach to the intestinal tissue and maintain its position long-term. Design challenges derive from the task of long-term mucosal adhesion which requires firm, quick-response attachment without …

Kinematics Of The Lower Extremities During Fundamental Martial Arts Tricking Techniques, Kevin P. Grassie

Honors Scholar Theses

Martial Arts Tricking (MAT) is a relatively new sport that combines martial arts, gymnastics, acrobatics, and breakdancing for the purposes of creating aesthetic and impressive combinations of kicks, flips and twists. It has been growing exponentially through social media and the overall athletic and entertainment communities. The sport is very unique in that the movements, with their blended influences, provide novel ways for athletes to generate and utilize their momentum in a creative way. The results often include off-axis flips and twists, single-leg landings, and complicated yet fluid techniques that easily chain together.

Due to the sport only being a …

Skin Strain Measurement To Predict Knee Joint Angles Through Nanocomposite Stain Gauges, Adin Martineau, James Tracy, Gavin Collins, Parker Rosquist, Dustin A. Bruening, Matt K. Seeley, David T. Fullwood, Anton E. Bowden

Biomedical Engineering Western Regional Conference

Explores the possibility of using high deflection nanocomposite strain gauges as knee joint angle sensor.

Characterization Of Essential Tremor In The Major Degrees Of Freedom Of The Upper Limb, Adam Pigg, David Standring, Steven Charles

Biomedical Engineering Western Regional Conference

No abstract provided.

Computational Characterization Of Blood Vessel Strain In Wire Myography, Sameer S. Nandikar, M Converse, K L. Monson

Biomedical Engineering Western Regional Conference

Blood vessels, and the mechanical forces that act on them, play a key role in both health and disease. As a consequence, the mechanical properties of vessels have been under study for over a century. A variety of approaches have been used to define vessel properties, including stretching of vessel rings to study circumferential behavior, a configuration commonly used in wire myography. The objective of the present study was to develop a finite element model to quantify strains throughout a vessel ring during such loading.

Using Optimization To Determine Tremor Propagation, Paul Curtis, Steven K. Charles

Biomedical Engineering Western Regional Conference

: Essential Tremor (ET) is one of the most common movement disorders, with millions affected in the US. Currently there are two main treatment options: medication and deep brain stimulation (DBS). Available medications are only 50% effective, and in only 50% of patients, and many patients consider DBS too invasive. The purpose of our research is to determine the origin and propagation of tremor throughout the upper limb.

Biophysical Tools To Study Cellular Mechanotransduction, Ismeel Muhamed, Farhan Chowdhury, Venkat Maruthamuthu

Mechanical & Aerospace Engineering Faculty Publications

The cell membrane is the interface that volumetrically isolates cellular components from the cell's environment. Proteins embedded within and on the membrane have varied biological functions: reception of external biochemical signals, as membrane channels, amplification and regulation of chemical signals through secondary messenger molecules, controlled exocytosis, endocytosis, phagocytosis, organized recruitment and sequestration of cytosolic complex proteins, cell division processes, organization of the cytoskeleton and more. The membrane's bioelectrical role is enabled by the physiologically controlled release and accumulation of electrochemical potential modulating molecules across the membrane through specialized ion channels (e.g., Na^⁺, Ca²⁺, K^⁺ channels). …

Piv Analysis Of Wake Structure Of Real Elephant Seal Whiskers, Joseph Antun Bunjevac

ETD Archive

Seals are able to accurately detect minute disturbances in the ambient flow
environment using their whiskers, which is attributed to the exceptional capability of
their whiskers to suppress vortex-induced vibrations in the wake. To explore potential applications for designing smart flow devices, such as high-sensitivity underwater
flow sensors and drag reduction components, researchers have studied how the role
of some key parameters of whisker-like morphology affect the wake structure. Due to
the naturally presented variation in size and curvature along the length of whiskers,
it is not well understood how a real whisker changes the surrounding flow and the
vortex …

Design And Control Of A Powered Rowing Machine With Programmable Impedance, Jose Humberto De La Casas Zolezzi

ETD Archive

Due to the rise of obesity, diabetes and cardiovascular disease, research in human performance and physical activity has received increased attention. Rowing machines are used for performance improvements through concentric exercises, however a combination of concentric and eccentric actions is known to improve the effectiveness of training. In this work, a conventional rowing machine was modified to include an electric motor and a robust impedance control system, enabling programmable impedance with concentric and eccentric capabilities. Eccentric exercises are known to contribute significantly to the efficacy of training and to diminish the detrimental effects of humans operating in microgravity for long …

Electroencephalographic Signal Processing And Classification Techniques For Noninvasive Motor Imagery Based Brain Computer Interface, Md Erfanul Alam

College of Graduate Studies: Theses & Dissertations

In motor imagery (MI) based brain-computer interface (BCI), success depends on reliable processing of the noisy, non-linear, and non-stationary brain activity signals for extraction of features and effective classification of MI activity as well as translation to the corresponding intended actions. In this study, signal processing and classification techniques are presented for electroencephalogram (EEG) signals for motor imagery based brain-computer interface. EEG signals have been acquired placing the electrodes following the international 10-20 system. The acquired signals have been pre-processed removing artifacts using empirical mode decomposition (EMD) and two extended versions of EMD, ensemble empirical mode decomposition (EEMD), and multivariate …

Bio Inspired Lightweight Composite Material Design For 3d Printing, Kaushik Thiyagarajan

Electronic Theses and Dissertations

Lightweight material design is an indispensable subject in product design. The lightweight material design has high strength to weight ratio which becomes a huge attraction and an area of exploration for the researchers as its application is wide and increasing even in every day-to-day product. Lightweight composite material design is achieved by selection of the cellular structure and its optimization. Cellular structure is used as it has wide multifunctional properties in addition to the lightweight characteristics. Applications of light weight cellular structures are wide and is witnessed in all industries from aerospace to automotive, construction to product design. In this …

Age-Related Differences In The Lumbopelvic Kinematics During The Trunk Motions In The Anatomical Planes, Milad Vazirian

Theses and Dissertations--Biomedical Engineering

Management and control of the low back pain as an important health problem in the industrial societies necessitates to investigate how the risk of this disease is affected by aging. Since the abnormalities of the lumbopelvic kinematics are related to the existence or risk of low back injuries, the objective of this dissertation was set to find the age-related differences in lumbopelvic kinematics when performing basic trunk motions reaching to range of motion in different anatomical planes.

A cross-sectional study was designed where sixty asymptomatic individuals between 20–70 years old with no confounding health condition, no current or previous highly …

Computational Investigation Of Transmural Differences In Left Ventricular Contractility And Hydrogel Injection Treatment For Myocardial Infarction, Hua Wang

Theses and Dissertations--Mechanical and Aerospace Engineering

Heart failure (HF) is one of the leading causes of death and impacts millions of people throughout the world. Recently, injectable hydrogels have been developed as a potential new therapy to treat myocardium infarction (MI). This dissertation is focused on two main topics: 1) to gain a better understanding the transmural contractility in the healthy left ventricle (LV) wall and 2) investigate the efficacy of the hydrogel injection treatment on LV wall stress and function. The results indicate that a non-uniform distribution of myocardial contractility in the LV wall provide a better representation of normal LV function. The other important …

Skintronics: Wireless, Skin-Wearable Electronics For Monitoring Of Electrocardiogram, Matthew B. Piper, Woon-Hong Yeo, Yongkuk Lee

Undergraduate Research Posters

The ECGs I micro-fabricate are designed to be flexible, stretchable and wireless circuits that can be applied to the skin directly. The device is encased in a conformal, silicon-like substrate, that allows the ECG to be attached with the electrodes. Each electrode has been previously measured and verified that it will be correctly placed for an accurate reading. Prototyping this ECG/electrode device allows the user to mount the prototype directly to the patient without having to attach and wire ten other electrodes. This prototype solves the issue that comes about when a doctor, nurse or emergency medical technician must attach …

Control Of A Powered Ankle-Foot Prosthesis: From Perception To Impedance Modulation, Guilherme Aramizo Ribeiro

Dissertations, Master's Theses and Master's Reports

Active ankle prostheses controllers are demonstrating gaining smart features to improve the safety and comfort offor users. The perception of user intention to modulate the ankle dynamics is a well-known example of such feature. But not much work focused on the perception of the environment, nor how the environment should be included in the mechanical design and control of the prosthesisprostheses. The proposed work aims to improve the feasibility of integrate the environment perception integration intoto the prostheses controllersler, and to define the desired ankle dynamics, as mechanical impedance, duringof the human walk on different environmental settings. As a preliminary …

Lighted Ear Curette, Kaitlin Klotzle, Kelsey Ashmore, Crysta Yamamoto, Katrina Elfrink, Cynthia Stoller

Williams Honors College, Honors Research Projects

The ear canal is a sensitive and small part of the human body that is prone to accumulate cerumen or lodge foreign bodies. In order to clean the ear canal or remove foreign bodies, three hands are required: one to brace the patient's head, one to maneuver the curette that is used to clean the ear, and one to hold a light source in order to make the small, dark area visible. Therefore, a design is needed that can allow a doctor to safely clean an ear with an instrument that only requires two hands. Furthermore, the design must have …

A 3d Fem Comparative Study On The Impact Response Between Human Head And Nocsae Head Due To Free Fall, Amey S. Badhe

Dissertations, Master's Theses and Master's Reports

We all enjoy sports be it watching or playing. Concussion is well known topic when it comes sports related injuries. However, concussion and brain injury is not exclusive to sports and outdoor activities. Sometimes, even the impact due to slip and fall at small heights can cause serious damage to the head and brain. This report studies the response generated in the human head model and the commercially use dummy NOCSAE headform due to drop from height of 2, 3, 4 and 5 feet. Earlier studies have related brain kinetics and head kinematics to concussion and traumatic brain injury (TBI). …

Using Lower Extremity Muscle Activations To Estimate Human Ankle Impedance In The External-Internal Direction, Lauren N. Knop

Dissertations, Master's Theses and Master's Reports

For millions of people, mobility has been afflicted by lower limb amputation. Lower extremity prostheses have been used to improve the mobility of an amputee; however, they often require additional compensation from other joints and do not allow for natural maneuverability. To improve upon the functionality of ankle-foot prostheses, it is necessary to understand the role of different muscle activations in the modulation of mechanical impedance of a healthy human ankle. This report presents the results of using artificial neural networks (ANN) to determine the functional relationship between lower extremity electromyography (EMG) signals and ankle impedance in the transverse plane. …

Simulation Of Human Ankle Trajectory During Stance Phase Of Gait, Leslie Castelino

Dissertations, Master's Theses and Master's Reports

A simulation was developed which mimics the human gait characteristics based on the input of an individual’s gait trajectory. This simulation also estimates the impedance of the human ankle based on the ground reaction forces measured by the force plate. This simulation will accept alterations of the following parameters: total body weight, weight of the shank, weight of the foot, trajectories of the shank and foot of the individual and orientation of the force plate, which would generate a new gait trajectory for the ankle during the stance phase of gait. The goal of this simulation was to validate the …

A Computational Study Of The Kinematics Of Femoroacetabular Morphology During A Sit-To-Stand Transfer, Brandon K. Marine

Theses and Dissertations

Computational modeling in the field of biomechanics is becoming increasingly popular and successful in practice for its ability to predict function and provide information that would otherwise be unobtainable. Through the application of these new and constantly improving methods, kinematics and joint contact characteristics in pathological conditions of femoroacetabular impingement (FAI) and total hip arthroplasty (THA) were studied using a lower extremity computational model. Patients presenting with FAI exhibit abnormal contact between the femoral neck and acetabular rim leading to surrounding tissue damage in daily use. THA is the replacement of both the proximal femur and acetabular region of the …

Nanocomposite Bioelectronics For Biopotential Enabled Prosthesis, Dong Sup Lee

Theses and Dissertations

Soft material-enabled electronics can demonstrate extreme mechanical flexibility and stretchability. Such compliant, comfortable electronics allow continuous, long-term measurement of biopotentials on the skin. Manufacturing of the stretchable electronic devices is enabled by the recent development combining materials transfer printing and microfabrication. However, the existing method using inorganic materials and multi-layered polymers requires long material preparation time and expensive processing cost due to the requirement of microfabrication tools and complicated transfer printing steps. Here, this study develops a new fabrication method of soft electronics via a micro-replica-molding technique, which allows fast production, multiple use, and low cost by avoiding microfabrication and …

Finite Element Modeling Of The Plantar Fascia: A Viscohyperelastic Approach, Alexander Knapp

UNF Graduate Theses and Dissertations

The present work details the creation and analysis of a finite element model of the foot, wherein the plantar fascia was modeled as a viscohyperelastic solid. The objective of this work was to develop a fully functional CAD and Finite Element Model of the foot and plantar fascia for analysis by examining the transient stresses on the plantar fascia through the use of a viscohyperelastic material model. The model’s geometry was developed through the use of image processing techniques with anatomical images provided by the National Institutes of Health. The finite element method was used to analyze the transient response …

Design And Evaluation Of Pediatric Gait Rehabilitation Robots, Cale J. Stolle

Department of Mechanical and Materials Engineering: Dissertations, Theses, and Student Research

Gait therapy methodologies were studied and analyzed for their potential for pediatric patients. Using data from heel, metatarsal, and toe trajectories, a nominal gait trajectory was determined using Fourier transforms for each foot point. These average trajectories were used as a basis of evaluating each gait therapy mechanism. An existing gait therapy device (called ICARE) previously designed by researchers, including engineers at the University of Nebraska-Lincoln, was redesigned to accommodate pediatric patients. Unlike many existing designs, the pediatric ICARE did not over- or under-constrain the patient’s leg, allowing for repeated, comfortable, easily-adjusted gait motions. This design was assessed under clinical …

An Emg-Based Patient Monitoring System Using Zynq Soc Device, Farhad Fallahlalehzari

UNLV Theses, Dissertations, Professional Papers, and Capstones

This thesis describes the design, development, and testing of an EMG-based patient monitoring system using the Zynq device. Zynq is a system on chip device designed by Xilinx which consists of an ARM dual cortex-A9 processor as well as an FPGA integrated into one chip. This work also analyzes the performance of image-processing algorithms on this system and compares that performance to more traditional PC-based systems. Image processing algorithms, such as Sobel edge detection, dilation and erosion, could be used in conjunction with a camera for the patient monitoring purposes. These algorithms often perform sub-optimally on processors because of their …

Radiation Therapy And Dosing Material Transport Methodology, Robert O'Brien

UNLV Theses, Dissertations, Professional Papers, and Capstones

A technique is examined here that utilizes high energy beta decays from a short lived radioisotope to treat medical conditions such as shallow cancerous lesions. A major benefit of beta particle interaction in tissue is a fixed penetration depth for the charged particle, with dose limited to the ultimate range of the beta particle. This method improves on some current techniques of radioactive brachytherapy, where "seeds" are placed inside patients through temporary or permanent implantation in order to kill cancerous cells or inhibit growth of tissue. The use of low energy gamma-rays is the most common method of treatment currently …