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Biomechanical Engineering Commons

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Full-Text Articles in Biomechanical Engineering

Three-Dimensional Printing Of Calcium Phosphate-Mesoporous Bioactive Glass Scaffolds For Bone Tissue Engineering, Ana Beatriz Gomes De Carvalho, Lais Medeiros Cardoso, Igor Paulino Mendes Soares, Joyce Rodrigues De Souza, Arpita Roy, Prabaha Sikder, Et. Al. Dec 2025

Three-Dimensional Printing Of Calcium Phosphate-Mesoporous Bioactive Glass Scaffolds For Bone Tissue Engineering, Ana Beatriz Gomes De Carvalho, Lais Medeiros Cardoso, Igor Paulino Mendes Soares, Joyce Rodrigues De Souza, Arpita Roy, Prabaha Sikder, Et. Al.

Mechanical Engineering Faculty Publications

Calcium phosphate cements (CPCs) and biomaterials, such as mesoporous bioactive glass (MBG), are critical for bone tissue engineering. This study aimed to 3D-print CPC scaffolds modified with MBG to enhance their osteogenic potential and regenerative ability. MBG powder was synthesized and characterized using transmission electron microscopy (TEM), X-ray diffraction (XRD), and nitrogen adsorption-desorption techniques. A commercial CPC ink (hydroxyapatite/alpha-tricalcium phosphate) was mixed with 5% MBG (w/w; CPC/MBG), and, after rheological assessment, the mixture was used to obtain scaffolds via 3D printing. These scaffolds were then tested for chemical, morphological, and mechanical properties, as well as ion release analysis. Unmodified CPC …


Generalizable Fugitive Carrier Method For 3d Printing Of Hydrogels, Hakan Arslan Jan 2024

Generalizable Fugitive Carrier Method For 3d Printing Of Hydrogels, Hakan Arslan

Mechanical and Aerospace Engineering Dissertations - Archive

Hydrogels, with physical characteristics resembling biological soft tissues, hold great potential for bioinspired and biomedical applications. However, using them in additive manufacturing systems has challenges because of their poor mechanical and rheological properties. In response to these challenges, we introduce a fugitive carrier method, a novel and generalizable approach for materials incompatible with pneumatic-based extrusion three-dimensional (3D) printers. Our developed fugitive carrier method allows the 3D printing of a broad spectrum of hydrogel precursors with low viscosity while retaining their inherent properties. This technique has been successfully demonstrated by creating biomimetic structures with anisotropic and programmable systems utilizing temperature-sensitive hydrogel …


Engineered Material Systems For Mimicking Tissue And Disease, Margrethe Ruding May 2023

Engineered Material Systems For Mimicking Tissue And Disease, Margrethe Ruding

McKelvey School of Engineering Graduate Student Theses & Dissertations

This thesis comprises two studies involving design and application of soft material systems. The goal of the first study was to design, fabricate, and characterize hydrogel lattice structures with consistent, controllable, anisotropic mechanical properties. Lattices, based on four types of unit cells (cubic, diamond, vintile, and Weaire-Phelan), were printed using stereolithography (SLA) of polyethylene glycol diacrylate (PEGDA). In order to create structural anisotropy in the lattices, unit cell design files were scaled in one direction by a factor of two in each layer and then printed. The mechanical properties of the scaled lattices were measured in shear and compression and …


Design Improvement Of Transcatheter Aortic Valves For Aortic Stenosis Patients, Samantha K. Shoun, Ali N. Azadani May 2022

Design Improvement Of Transcatheter Aortic Valves For Aortic Stenosis Patients, Samantha K. Shoun, Ali N. Azadani

DU Undergraduate Research Journal Archive

Aortic valve disease is a common condition in patients above 60 years of age and is associated with significant morbidity and mortality. Aortic valve stenosis is characterized by the narrowing of the aortic valve, which can be quite debilitating. This disease is treated with transcatheter aortic valve replacement (TAVR), which is a rapidly expanding alternative to open-heart surgical aortic valve replacement (SAVR). Although TAVR is a less invasive than SAVR, long-term durability of the transcatheter aortic valves could be the Achilles heel of the procedure. Thus, the main objective of this research was to improve the design of transcatheter aortic …


In The Pursuit Of Assistance: A Team's Desire To Not Let A Congenital Amputation Get In A Young Boy's Way, Carl Russell Iii, Gavin Loucks, Kirsten Wozniak Oct 2020

In The Pursuit Of Assistance: A Team's Desire To Not Let A Congenital Amputation Get In A Young Boy's Way, Carl Russell Iii, Gavin Loucks, Kirsten Wozniak

Purdue Journal of Service-Learning and International Engagement

EPICS is a service-learning design program run through Purdue University. It strives to teach students design skills through providing for individuals, communities, and organizations in the surrounding area while mirroring engineering industry standards. BME (Biomedical Engineering) is a team within EPICS that strives to serve community partners through biomedical applications. William Sevick is an elementary school student with a congenital arm amputation. William and his family have been working with the BME team for the past three years designing assistive devices with the purpose of improving his actions in daily life such as eating, playing games, and riding his bike.


Binder Saturation, Layer Thickness, Drying Time And Their Effects On Dimensional Tolerance And Density Of Cobalt Chrome - Tricalcium Phosphate Biocomposite, John Ruprecht Jan 2020

Binder Saturation, Layer Thickness, Drying Time And Their Effects On Dimensional Tolerance And Density Of Cobalt Chrome - Tricalcium Phosphate Biocomposite, John Ruprecht

All Graduate Theses, Dissertations, and Other Capstone Projects

Traditional metals such as stainless steel, titanium and cobalt chrome are used in biomedical applications (implants, scaffolds, etc.) but suffer from issues such as osseointegration and compatibility with existing bone. One way to improve traditional biomaterials is to incorporate ceramics with these metals so that their mechanical properties can be similar to cortical bones. Tricalcium phosphate is such a ceramic with properties such that it can be used in the human body. This research explores the use of the Binder Jetting based additive manufacturing process to create a novel biocomposite made of cobalt chrome and tricalcium phosphate. Experiments were conducted …


Developing A Testing Instrument To Evaluate The Performance Of 3d-Printed Body-Powered Prosthetic Hands, Araz Al-Dawoodi Jan 2019

Developing A Testing Instrument To Evaluate The Performance Of 3d-Printed Body-Powered Prosthetic Hands, Araz Al-Dawoodi

All Graduate Theses, Dissertations, and Other Capstone Projects

A 3D printed prosthetic hand is an open source technology that became a good substitution for many products in the market. For many reasons, Low-cost, easy made / easy build. As an open source product, 3D printed prosthetic designs are available to anyone around the world, a good option for young children because they need to have a new prosthetic more frequent until they reach the adulthood age. Most families cannot pay a thousand dollars technology. From the research, it found that that there are not enough studies cover the open source wrist body-powered prosthetic. Other studies covered products used …


Bio Inspired Lightweight Composite Material Design For 3d Printing, Kaushik Thiyagarajan Jan 2017

Bio Inspired Lightweight Composite Material Design For 3d Printing, Kaushik Thiyagarajan

Electronic Theses and Dissertations

Lightweight material design is an indispensable subject in product design. The lightweight material design has high strength to weight ratio which becomes a huge attraction and an area of exploration for the researchers as its application is wide and increasing even in every day-to-day product. Lightweight composite material design is achieved by selection of the cellular structure and its optimization. Cellular structure is used as it has wide multifunctional properties in addition to the lightweight characteristics. Applications of light weight cellular structures are wide and is witnessed in all industries from aerospace to automotive, construction to product design. In this …