How Environmental Change Will Impact Mosquito-Borne Diseases, 2022 The University of San Francisco
How Environmental Change Will Impact Mosquito-Borne Diseases, Arsal Khan
Master's Projects and Capstones
Mosquitos, the most lethal species throughout human history, are the most prevalent source of vector-borne diseases and therefore a major global health burden. Mosquito-borne disease incidence is expected to shift with environmental change. These changes can be predicted using species distribution models. With the wide variety of methods used for models, consensus for improving accuracy and comparability is needed. A comparative analysis of three recent modeling approaches revealed that integrating modeling techniques compensates for trade-offs associated with a singular approach. An area that represents a critical gap in our ability to predict mosquito behavior in response to changing climate factors ...
Alternate Site Pacing And The Impact On Intracellular Calcium Handling During The Post-Extrasystolic Cardiac Cycle, Kent Ozcan, Lawrence Mulligan
Stratford Campus Research Day
Objective: Previous work has shown that alternate site (RV apex) results in myocardial dysfunction. With the development of tools to place endocardial pacing leads in locations that create physiological pacing activation, we sought to evaluate how ventricular trans-septal or left ventricular apical placement pacing differs from right atrial pacing. We will evaluate how these chronic pacing modes impact the PR and RF at baseline, 0, and 16 weeks in the canine heart.
Methods: Quantitative analysis will be performed on previously generated data. The data set includes pacing of 15 dogs total (8 with trans-septal leads & 7 with left ventricular apical ...
A Case Report On Causes Of Covid-19 Induced Psychosis And Treatments, 2022 Rowan University
A Case Report On Causes Of Covid-19 Induced Psychosis And Treatments, Jennifer Pires, Steven Sarner
Stratford Campus Research Day
COVID-19 is a viral infection that is caused by an RNA virus in a subfamily of Coronaviridae named severe acute respiratory syndrome (SARS CoV 2). The family also includes severe acute respiratory syndrome coronavirus (SARS CoV) and middle east respiratory syndrome coronavirus (MERS CoV) which have previously been shown to cause respiratory symptoms and psychosis with immunoreactivity to IgG.
A Neurophysiological Investigation Of Listening Effort In Normal Hearing Adults Using Fnirs And Pupillometry, 2022 University of Tennessee Health Science Center
A Neurophysiological Investigation Of Listening Effort In Normal Hearing Adults Using Fnirs And Pupillometry, Jessica Defenderfer
Theses and Dissertations (ETD)
Real-world conversations are often accompanied by some sort of interference that challenges the clarity of the speaker’s message, causing listeners to exert more effort to understand speech. Previous research has demonstrated that when listening to speech becomes difficult, various regions of the brain are recruited beyond those which engage during optimal listening conditions. However, the neural correlates that underly listening effort are not fully understood. Importantly, the pupillary response can be used to index listening effort, such that pupil size increases with increasing cognitive demand. I proposed that pupillometry can be used to characterize the cortical response, such that ...
Parkinson's Disease And Exercise: Steps Into A Hopeful Future, 2022 Longwood University
Parkinson's Disease And Exercise: Steps Into A Hopeful Future, Jacob Barker
Spring Showcase for Research and Creative Inquiry
In the world of medicine and disease interventions, exercise is too often underlooked as a viable form of treatment or complementary treatment to medication. This is especially true with Parkinson’s Disease, a disease that attacks the basal ganglia of the brain and impairs neuromuscular function. In my analysis, I read a perspective from a PD patient, Gerry Hill, who has struggled with the disease himself and how he used physical activity to aid in his battle with the disease for both physical and psychological aid. Additionally, I performed research to understand how exercise benefits function within the brain. Aerobic ...
Biostimulation With Low-Level Laser Therapy And Its Effects On Soft And Hard Tissue Regeneration. Literature Review, 2022 Iuliu Hatieganu University of Medicine and Pharmacy
Biostimulation With Low-Level Laser Therapy And Its Effects On Soft And Hard Tissue Regeneration. Literature Review, Anida Maria Babtan, Aranka Ilea, Claudia Nicoleta Feurdean, Sabino Ceci, Berate Pula, Sebastian Candrea, Daniela Azzollini, Fabio Piras, Luigi Curatoli, Alberto Corriero, Assunta Patano, Francesco Valente, Maria Elena Maggiore, Antonio Mancini, Delia Giovanniello, Ludovica Nucci, Rossella Elia, Adina Sirbu, Nausica Bianca Petrescu, Codruta Mirica, Andrea Galderisi, Filippo Cardarelli
Journal of Mind and Medical Sciences
Objective. Low-Level Laser Therapy encourages the healing process, reduces inflammation and pain. The aim of this study is to identify the impact of Low-Level Laser Therapy on tissue regeneration with special attention to hard tissues and to compare the effect of several wave lengths in the proliferation and differentiation of cells. Methods. The keywords used were “bone regeneration”, “laser therapy”, “photobiomodulation” OR “bio-stimulation”, “Low-Level Laser therapy” OR “LLLT”, “osteoblast proliferation” AND “differentiation”. Results. The bio-stimulation with Low-Level Laser Therapy also seems to interfere with the osseous integration of implants, by increasing its adherence on the bone-implant surfaces. Evidence has shown ...
The Vespa Project: Virtual Reality Interventions For Neurocognitive And Developmental Disorders, 2022 University of Messina, Department of Adult and Childhood Human Pathology “Gaetano Barresi”, Messina, Italy
The Vespa Project: Virtual Reality Interventions For Neurocognitive And Developmental Disorders, Emanuele Maria Merlo, Liam Alexander Mackenzie Myles, Salvatore Marco Pappalardo
Journal of Mind and Medical Sciences
VESPA is a financed project supported by the Sicilian Regional Research and Development funds, and it is structured by the development, research and validation of Virtual Reality (VR) based application for the diagnosis and treatment of neurocognitive conditions. In particular, this article presents its characteristics, referred to as the first (2013-2015) and second (2021-ongoing) generations of VESPA, with particular reference to literature regarding the VR technology application and development, the VR treatment of neurocognitive conditions and prior versions of this intervention. Through a comprehensive review of the research conducted over the last 5 years, evidence has emerged supporting VESPA’s ...
Influence Of Core Temperature On Psychomotor Performance During Cold Weather Military Training, 2022 Naval Health Research Center
Influence Of Core Temperature On Psychomotor Performance During Cold Weather Military Training, Douglas Jones, Rebecca Weller, Stephen Eggan, Nicholas Roberts, Weimin Zheng, Jay Heaney, Timothy Dunn
Journal of Human Performance in Extreme Environments
Purpose: Cold environments may deteriorate psychomotor performance due to slowing of neuronal signals, distractions caused by pain and discomfort, and a loss of manual dexterity. The extent to which core temperature (Tc) influences psychomotor performance in the cold has not been established. Therefore, psychomotor performance and Tc were assessed during a cold weather military training exercise to evaluate this relationship.
Methods: Thirty-six military personnel (age: 26 ± 4 yr, ht: 175 ± 8 cm, wt: 79.1 ± 11.1 kg) participating in cold weather training volunteered for this study. Participants completed a 10-min immersion in cold (1°C) water, followed ...
The Impact Of High Intensity Interval Training On Neurogenesis And Angiogenesis In The Dentate Gyrus, 2021 Seton Hall University
The Impact Of High Intensity Interval Training On Neurogenesis And Angiogenesis In The Dentate Gyrus, Darrin Lenhart
Seton Hall University Dissertations and Theses (ETDs)
BACKGROUND: Exercise is associated with improved neuronal health and longevity, synaptic plasticity, cerebral blood volume, overall brain volume, and neurogenesis which collectively may have the power to forestall neurodegenerative disease.
PURPOSE: This study aims to explore the impact of high intensity interval training on individuals with mild cognitive impairment using a range of cognitive, physiological, and biomechanical measures. Specifically, this study seeks to assess the impact of high intensity interval training on neurogenesis and angiogenesis in the dentate gyrus of individuals with mild cognitive impairment versus healthy age-matched controls, as assessed by urinalysis of BDNF levels, performance on the Rey ...
Effects Of Hormone Replacement Therapy (Hrt) On Gene Expression In The Amyloid Processing Pathway Of Ovariectomized Rhesus Macaque Females Under An Obesogenic Diet, Megan Ball
University Honors Theses
Estrogens rapidly decline at the onset of menopause, putting women at higher risk of osteoporosis, obesity, and neurodegenerative diseases, including Alzheimer’s disease (AD). Estradiol hormone therapies (HT) have been suggested to limit these negative effects on women, with controversial findings as to their effectiveness. A study at OHSU recently found differentially expressed genes (DEGs) using RNAseq between ovariectomized/hysterectomized (OvH) old (range = 19.4–23.2 years) female rhesus macaques on HT and those on a placebo on chronic western style diet (WSD). The DEGs identified in the amyloid processing pathway of the amygdala were selected for validation using ...
Modulation Of Glucose Homeostasis By Nucleotide P2y2 Receptor And Biological Sex, 2021 Missouri State University
Modulation Of Glucose Homeostasis By Nucleotide P2y2 Receptor And Biological Sex, Hailee Anne Marino
MSU Graduate Theses
Recent insights into the pathological role of Nucleotide P2Y2 receptor suggest P2Y2R involvement in high fat diet-induced obesity and potentiates insulin resistance. However, these recent insights do not demonstrate how P2Y2R modulates glucose homeostasis under physiological conditions. Further, it remains unknown how sex biological factors influence P2Y2R receptor signaling in the regulation of glucose homeostasis. The research objective for the present study is to elucidate the novel roles of P2Y2 in fasting blood glucose and glucose tolerance (basal insulin sensitivity) under resting conditions in males and females. We expected that under physiological ...
Malignant Hyperthermia, 2021 Otterbein University
Malignant Hyperthermia, Joel Jackson
Nursing Student Class Projects (Formerly MSN)
Malignant hyperthermia (MH) is a hypermetabolic response to succinylcholine or inhaled volatile gases administered during anesthesia and is caused by an autosomal dominant mutation of RYR1 or CACNA1S genes which affect how calcium channels function. The uncontrolled, unopposed calcium release and excitation-contraction coupling results in sustained skeletal muscle contraction resulting in muscle rigidity, hyperthermia, hypercapnia, hypertension, and tachycardia among other less common clinical features. The sequelae of an MH crisis include renal failure, rhabdomyolysis, hyperkalemia, metabolic disturbance and left untreated will result in mortality. All clinicians involved in peri-operative care both in-hospital and out of hospital must be cognizant of ...
Analysis Of Occupational Therapy’S Role To Promote Healthy Sleep Participation To Support Caregivers Of Children With Autism Spectrum Disorder, 2021 University of St. Augustine for Health Sciences
Analysis Of Occupational Therapy’S Role To Promote Healthy Sleep Participation To Support Caregivers Of Children With Autism Spectrum Disorder, Sophia N. Roman
Student Capstone Projects
Children with autism spectrum disorder (ASD) face sleep disturbances. Healthy sleep habits are essential for children with ASD and their caregivers to properly engage in their everyday lives. Occupational therapists are trained to evaluate clients in areas that contribute to sleep dysfunction and to focus on promoting optimal sleep performance. There is limited research on caregivers’ perceptions of their child’s sleep disturbances, these disturbances’ influence on occupational engagement, and whether occupational therapists have collaborated with caregivers of children with ASD to treat this area of occupation. Collecting data from caregivers by using a questionnaire can provide occupational therapy (OT ...
Utility Of Cognitive Behavioral Therapy To Reduce Pain In Children With Sickle Cell Disease, 2021 Wayne State University
Utility Of Cognitive Behavioral Therapy To Reduce Pain In Children With Sickle Cell Disease, Abigail Radomsky
Clinical Research in Practice: The Journal of Team Hippocrates
A clinical decision report appraising:
Schatz J, Schlenz AM, McClellan CB, et al. Changes in coping, pain, and activity after cognitive-behavioral training. The Clinical Journal of Pain 2015;31(6):536-47 https://doi.org/10.1097/ajp.0000000000000183
for a child with sickle cell disease.
Reiki For Recovery: Incorporating Japanese Health Practices To Increase Contemporary Resiliency In American Health, 2021 The University of San Francisco
Reiki For Recovery: Incorporating Japanese Health Practices To Increase Contemporary Resiliency In American Health, Leif Peterson
Master's Projects and Capstones
The Japanese health practice of Reiki attempts to maximize the latent ability of the human system to heal itself. The Reiki system, established over a century ago, combines multiple Asian health traditions, experimenting with practices that maximize the natural processes of the body to perform its own repairs. Reiki encourages healthy behaviors that balance the mind and body, return the human system to a lowered stress level, and allow for an optimal recovery state for the patient. This paper illustrates how this Japanese health-affirming method can be integrated and utilized within existing health and medical practices. An area that is ...
The Relationship Of Divine Forgiveness, Victim Forgiveness, And Physical Health Mediated By Stress, 2021 Liberty University
The Relationship Of Divine Forgiveness, Victim Forgiveness, And Physical Health Mediated By Stress, Lemuel Josiah C. Ragasajo
Senior Honors Theses
Though there is increasing evidence to support a relationship between forgiveness and physical health, certain subcategories of forgiveness, namely victim and divine forgiveness, are relatively understudied. This study seeks to add to the body of forgiveness literature by examining how divine and victim forgiveness relate to one’s physical health, and whether that relationship is mediated by stress. Furthermore, a literature review is included to detail how stress, a potential mediating variable between forgiveness and physical health, affects physical health. The results of the study reveal that victim forgiveness positively predicts physical health, but is not mediated by stress. In ...
Affiliative Social Interactions Activate Vasopressin-Responsive Neurons In The Mouse Dorsal Raphe, Tirth Patel, Hanna O. Caiola, Olivia Mallari, Benjamin D. Rood
Stratford Campus Research Day
Social behavior is inextricably linked to human health, shaping both our susceptibility and resilience to disease and stress. Positive interactions as simple as maternal contact or friendships among children and adults can protect against emotional distress and improve treatment outcomes, whereas negative interactions such as abuse, social isolation, or bullying can increase aggression and precipitate mood disorders. Discovering the structure and function of neural circuits underlying social behavior is critical to understanding the link between social interaction and health. The neuropeptide vasopressin has been implicated in the regulation of multiple social interactions including social memory, aggression, mating, pair-bonding, and parental ...
Identification Of The E3 Ligase That Directs The Degradation Of Proteins That Control Cell Fate Decisions In Yeast, Prasanna Tati, Stephen D Willis, Katrina F. Cooper
Stratford Campus Research Day
The ubiquitin–proteasome system (UPS) and autophagy pathways are distinct, highly conserved proteolytic systems that play important roles in maintaining cellular homeostasis in response to environmental cues . The goal of this project is to identify the E3 ligase that mediates the degradation of cyclin C following nitrogen starvation in yeast using quantitative Western blot analysis of cyclin C-myc following nitrogen starvation in mutants of known Ubc4/5 interacting E3 ligases. No potential E3 ligases were identified as stable after 4 hours of nitrogen starvation, suggesting redundancy in function.
Is There A Characteristic Autonomic Response During Outbursts Of Combative Behavior In Dementia Patients, 2021 University of Massachusetts Medical School
Is There A Characteristic Autonomic Response During Outbursts Of Combative Behavior In Dementia Patients, Curtis K. Deutsch, Pooja P. Patnaik, Frank A. Greco
Open Access Publications by UMass Chan Authors
We sought to determine whether skin conductance level could warn of outbursts of combative behavior in dementia patients by using a wristband device. Two outbursts were captured and are reported here. Although no physiologic parameter measured by the wristband gave advance warning, there is a common pattern of parasympathetic withdrawal (increased heart rate) followed approximately 30 seconds later by sympathetic activation (increased skin conductance). In the literature, a similar pattern occurs in psychogenic non-epileptic seizures. We hypothesize that similar autonomic responses reflect similarities in pathophysiology and that physical activity may partially account for the time course of skin conductance.
Differential Effects Of Kim-1 In Subcutaneous And Orthotopic Renca Models Of Kidney Cancer, 2021 The University of Western Ontario
Differential Effects Of Kim-1 In Subcutaneous And Orthotopic Renca Models Of Kidney Cancer, Demitra M. Yotis Dy
Electronic Thesis and Dissertation Repository
Renal Cell Carcinoma (RCC) is the most common and fatal type of kidney cancer. Over 30% of patients that are diagnosed with RCC exhibit metastases. Almost 88% of patients with distant metastases succumb to the disease within 5 years of diagnosis. Kidney Injury Molecule-1 (KIM-1) is a cell surface glycoprotein that is not expressed in a healthy kidney but becomes highly expressed on proximal tubular epithelial cells (PTECs) following injury. Data from the Cancer Genome Atlas (TCGA) reveals that >90% of RCC tumours express KIM-1 mRNA and that higher expression levels correlate with increased overall survival rates of patients. The ...