Genetic Processes Commons™
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Recent Articles in Genetic Processes
Tumour Heterogeneity And Treatment: One Step Forward Or Two Steps Back?, Branavan Manoranjan, Mohsin Ali 
McMaster University
Tumour Heterogeneity And Treatment: One Step Forward Or Two Steps Back?, Branavan Manoranjan, Mohsin Ali
The Meducator
No abstract provided.
Β-Catenin Overexpression Within The Metanephric Mesenchyme Causes Renal Dysplasia Via Upregulation Of The Gdnf Signalling Axis, Sanjay Sarin McMaster University
Β-Catenin Overexpression Within The Metanephric Mesenchyme Causes Renal Dysplasia Via Upregulation Of The Gdnf Signalling Axis, Sanjay Sarin
Open Access Dissertations and Theses
Renal dysplasia, a developmental disorder characterized by defective nephrogenesis and branching morphogenesis, ranks as one of the major causes of renal failure among the pediatric population. The molecular mechanisms underlying the pathogenesis of renal dysplasia are not well understood; however, changes in gene expression are a major contributing factor. In this study, we demonstrate that the levels of activated β-catenin, a transcriptional co-regulator, are elevated in the nuclei of ureteric, stromal, and mesenchymal cells within dysplastic human kidney tissue. To determine the mechanisms by which mesenchymal β-catenin over-expression leads to renal dysplasia, we generated a conditional mouse model in which ...
Popular Institutions
Popular Authors
Robert Brent
Thomas Jefferson University
Kim Cardenas
Texas Medical Center Library
Solsire Zevallos
University of Pennsylvania
Angela van Daal
Bond University
Bruce Budowle
Bond University
Mustafa Raoof
Texas Medical Center Library
Elizabeth Rose
Claremont Colleges
Fergus Ryan
Dublin Institute of Technology
Neil Dattani
McMaster University
Vithooshan Vijayakumaran
McMaster University
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Popular Articles
Teratology Primer-2nd Edition (7/9/2010), Robert Brent
Enforced Expression Of Tbx1 In Fetal Thymic Epithelial Cells Antagonizes Thymus Organogenesis, Kim Cardenas
The Role Of Sonic Hedgehog In The Hypothalamus, Solsire Zevallos
Identification And Characterization Of Novel Sir3/Mecp2-Chromatin Interactions
Forensically Relevant Snp Classes, Angela van Daal, Bruce Budowle
Chemosensitization Of Hepatocellular Carcinoma To Gemcitabine By Non-Invasive Radiofrequency Field-Induced Hyperthermia, Mustafa Raoof
Epigenetics: Blurring The Line Between Nature And Nurture, Elizabeth Rose
Heart Disease, Longevity, And Cholesteryl Ester Transfer Protein, Neil Dattani, Vithooshan Vijayakumaran
Detection Of Five Common Cftr Mutations By Rapid-Cycle Real-Time Amplification Refractory Mutation System Pcr, Fergus Ryan
Activity Of Analogs Of Anticancer Drugs On The Serine Protease Enzymes Subtilisin And Chymotrypsin, Dhatri Ravipati
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