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Skeletal Manifestations Of Scurvy: A Case Report From Dubai, Shahryar Noordin, Naveed Baloch, Muhammad Sohail Salat, Abdul Rashid Memon, Tashfeen Ahmad 2012 Aga Khan University

Skeletal Manifestations Of Scurvy: A Case Report From Dubai, Shahryar Noordin, Naveed Baloch, Muhammad Sohail Salat, Abdul Rashid Memon, Tashfeen Ahmad

Section of Orthopaedic Surgery

Introduction: Nutritional deficiencies are rarely reported in developed countries. We report a child of Pakistani origin brought up in Dubai who developed skeletal manifestations of scurvy due to peculiar dietary habits.
Case Presentation: A 4.5 year old boy presented with pain and swelling of multiple joints for three months and inability to walk for two months. Dietary history was significant for exclusive meat intake for the preceding two years. On examination the child's height and weight were below the 5th percentile for his age. He was pale and tachycardic. There was significant swelling and tenderness over the wrist, knee and …


Duhamel's Procedure For Adult Hirschsprung's Disease, Mehreen Adhi, Salma Khan, Hasnain Zafar, Muhammad Arshad 2012 Aga Khan University

Duhamel's Procedure For Adult Hirschsprung's Disease, Mehreen Adhi, Salma Khan, Hasnain Zafar, Muhammad Arshad

Section of General Surgery

An adult presented with chronic constipation and abdominal mass. Clinical features, abdominal radiographs and barium enema revealed features consistent with Hirschsprung's disease. Full-thickness rectal biopsy was planned, but patient was lost to follow-up and presented 3 years later with intestinal obstruction. Exploratory laparotomy with resection of affected sigmoid colon and end colostomy were performed. Sequential rectal biopsies were obtained during the procedure to confirm the diagnosis. Later, Duhamel's procedure with a diverting loop ileostomy was successfully performed. Ileostomy reversal was done thereafter. There was complete resolution of symptoms and dramatic improvement in bowel function.


Corneal Swapping In A Bomb Blast Victim, Tanveer Anjum Chaudhry, Tahreem Aman, Farheen Shaikh, Khabir Ahmad 2012 Aga Khan University

Corneal Swapping In A Bomb Blast Victim, Tanveer Anjum Chaudhry, Tahreem Aman, Farheen Shaikh, Khabir Ahmad

Section of Ophthalmology

The case of a 40-year-old-man who presented to our clinic with bilateral blindness as a consequence of bomb blast injuries is reported. He had a completely opaque cornea, partially damaged posterior segment and perception of light in the right eye, while a clear cornea, totally damaged posterior segment and no light perception in the fellow eye. His corneas were successfully swapped which gave him navigational vision.


James Marion Sims, M.D., Ll.D., Jonathan Tavares, B.S., Charles J. Yeo, MD, Pinckney J. Maxwell, IV, MD 2012 Thomas Jefferson University

James Marion Sims, M.D., Ll.D., Jonathan Tavares, B.S., Charles J. Yeo, Md, Pinckney J. Maxwell, Iv, Md

Department of Surgery Gibbon Society Historical Profiles

Few physicians have been as celebrated and loathed as James Marion Sims, M.D., LL.D. Dr. Sims’ modest early life and education never could have predicted that he would one day be called the ‘‘Father of American Gynecology.’’1, 2 Lauded by contemporaries and early historians as ‘‘one of the most original and gifted of American surgeons,’’ he performed the first successful operation to correct vesicovaginal fistulas (a condition that prior to 1852 was known as the ‘‘stumbling-block of gynecology’’).1 Today, the same work that earned Dr. Sims fame, fortune, and innumerable honors has been called into question, because of the unethical …


Childhood Unintentional Injuries: Need For A Community-Based Home Injury Risk Assessments In Pakistan., Adnan A. Hyder, Aruna Chandran, Uzma R. Khan, Nukhba Zia, Cheng-Ming Huang, Sarah Stewart de Ramirez, Junaid Razzak 2012 Johns Hopkins University Bloomberg School of Public Health

Childhood Unintentional Injuries: Need For A Community-Based Home Injury Risk Assessments In Pakistan., Adnan A. Hyder, Aruna Chandran, Uzma R. Khan, Nukhba Zia, Cheng-Ming Huang, Sarah Stewart De Ramirez, Junaid Razzak

Department of Emergency Medicine

Background. A substantial proportion of the annual 875,000 childhood unintentional injury deaths occur in the home. Very few printed tools are available in South Asia for disseminating home injury prevention information. Methods. Three tools were planned: an injury hazard assessment tool appropriate for a developing country setting, an educational pamphlet highlighting strategies for reducing home injury hazards, and an in-home safety tutorial program to be delivered by a trained community health worker. Results. The three tools were successfully developed. Two intervention neighborhoods in Karachi, Pakistan, were mapped. The tools were pretested in this local setting and are now ready for …


Lvhn: The Level Ii Accreditation Journey, Cathyann Feher RN,MSN, Karen L. Kutner MBA, Michael M. Badellino MD,FACS 2012 Lehigh Valley Health Network

Lvhn: The Level Ii Accreditation Journey, Cathyann Feher Rn,Msn, Karen L. Kutner Mba, Michael M. Badellino Md,Facs

Department of Surgery

No abstract provided.


Spontaneous Coronary Artery Dissection: A Rare But Deadly Cause Of Acs In Younger Patients, Daniel J. Makowski DO, David A. Cox MD 2012 Lehigh Valley Health Network

Spontaneous Coronary Artery Dissection: A Rare But Deadly Cause Of Acs In Younger Patients, Daniel J. Makowski Do, David A. Cox Md

Department of Medicine

No abstract provided.


Evaluating The Impact Of Prior Hospital Mortality Versus Surgical Volume On Length Of Stay Following Pediatric Congenital Cardiac Surgery In New York State, Ming Liu 2012 University at Albany, State University of New York

Evaluating The Impact Of Prior Hospital Mortality Versus Surgical Volume On Length Of Stay Following Pediatric Congenital Cardiac Surgery In New York State, Ming Liu

Legacy Theses & Dissertations (2009 - 2024)

Objective: To examine the relationship of prior hospital surgical volume and risk-adjusted mortality rate with future length of stay for children undergoing congenital cardiac surgery in New York State.


Preoperative Fdg-Pet/Ct Is An Important Tool In The Management Of Patients With Thick (T4) Melanoma., Rodrigo Arrangoiz, Pavlos Papavasiliou, Carrie A Stransky, Jian Q Yu, Li Tianyu, Elin R Sigurdson, Adam C Berger, Jeffrey M Farma 2012 Department of Surgical Oncology, Fox Chase Cancer Center

Preoperative Fdg-Pet/Ct Is An Important Tool In The Management Of Patients With Thick (T4) Melanoma., Rodrigo Arrangoiz, Pavlos Papavasiliou, Carrie A Stransky, Jian Q Yu, Li Tianyu, Elin R Sigurdson, Adam C Berger, Jeffrey M Farma

Department of Surgery Faculty Papers

The yield of preoperative PET/CT (PET/CT) for regional and distant metastases for thin/intermediate thickness melanoma is low. Objective of this study is to determine if PET/CT performed for T4 melanomas helps guide management and alter treatment plans. Methods. Retrospective cohort of 216 patients with T4 melanomas treated at two tertiary institutions. Fifty-six patients met our inclusion criteria (T4 lesion, PET/CT and no clinical evidence of metastatic disease). Results. Fifty-six patients (M: 32, F: 24) with median tumor thickness of 6 mm were identified. PET/CT recognized twelve with regional and four patients with metastatic disease. Melanoma-related treatment plan was altered in …


Bickerstaff’S Brainstem Encephalitis, Miller Fisher Syndrome And Guillain-Barré Syndrome Overlap In An Asthma Patient With Negative Anti-Ganglioside Antibodies, Chongyu Han, Yuan Wang, Jianping Jia, Xunming Ji, Vance Fredrickson, Yuchuan Ding, Wei Sun, Jia Xu, Yong-Xin Sun 2012 You Anmen Hospital

Bickerstaff’S Brainstem Encephalitis, Miller Fisher Syndrome And Guillain-Barré Syndrome Overlap In An Asthma Patient With Negative Anti-Ganglioside Antibodies, Chongyu Han, Yuan Wang, Jianping Jia, Xunming Ji, Vance Fredrickson, Yuchuan Ding, Wei Sun, Jia Xu, Yong-Xin Sun

Wayne State University Associated BioMed Central Scholarship

Abstract

Background

Bickerstaff’s brainstem encephalitis (BBE), together with Miller Fisher syndrome (MFS) and Guillain-Barré syndrome (GBS) were considered to form a continuous clinical spectrum. An anti-GQ1b antibody syndrome has been proposed to underlie the common pathophysiology for the three disorders; however, other studies have found a positive anti-GM1 instead of anti-GQ1b antibody.

Case presentation

Here we report a 20-year-old male patient with overlapping BBE, MFS and GBS. The patient had a positive family history of bronchial asthma and had suffered from the condition for over 15 years. He developed BBE symptoms nine days after an asthma exacerbation. During the course …


Evaluation Of Stress On Laparoscopic Skills Of Surgical Residents In Simulation-Based Education, William C. Boyer DHSc, MS, Hubert K. Huang MS,MEd, Charles Scagliotti MD,FFACS, Robert Ruhf 2012 Lehigh Valley Health Network

Evaluation Of Stress On Laparoscopic Skills Of Surgical Residents In Simulation-Based Education, William C. Boyer Dhsc, Ms, Hubert K. Huang Ms,Med, Charles Scagliotti Md,Ffacs, Robert Ruhf

Department of Education

No abstract provided.


Penile Enhancement Procedures With Simultaneous Penile Prosthesis Placement, Tariq S. Hakky, Jessica Suber, Gerard Henry, David Smith, Paul Bradley, Daniel Martinez, Rafael E. Carrion 2012 University of South Florida

Penile Enhancement Procedures With Simultaneous Penile Prosthesis Placement, Tariq S. Hakky, Jessica Suber, Gerard Henry, David Smith, Paul Bradley, Daniel Martinez, Rafael E. Carrion

Surgery Faculty Publications

Here we present an overview of various techniques performed concomitantly during penile prosthesis surgery to enhance penile length and girth. We report on the technique of ventral phalloplasty and its outcomes along with augmentation corporoplasty, suprapubic lipectomy, suspensory ligament release, and girth enhancement procedures. For the serious implanter, outcomes can be improved by combining the use of techniques for each scar incision. These adjuvant procedures are a key addition in the armamentarium for the serious implant surgeon


The Florida Melanoma Trial I: A Prospective Multicenter Phase I/Ii Trial Of Postoperative Hypofractionated Adjuvant Radiotherapy With Concurrent Interferon-Alfa-2b In The Treatment Of Advanced Stage Iii Melanoma With Long-Term Toxicity Follow-Up, Steven E. Finkelstein, Andy Trotti, Nikhil Rao, Douglas Reintgen, Wayne Cruse, Lynn Feun, Vernon Sondak, Daohai Yu, Weiwei Zhu, Clement Gwede, Ronald DeConti 2012 Moffitt Cancer Center

The Florida Melanoma Trial I: A Prospective Multicenter Phase I/Ii Trial Of Postoperative Hypofractionated Adjuvant Radiotherapy With Concurrent Interferon-Alfa-2b In The Treatment Of Advanced Stage Iii Melanoma With Long-Term Toxicity Follow-Up, Steven E. Finkelstein, Andy Trotti, Nikhil Rao, Douglas Reintgen, Wayne Cruse, Lynn Feun, Vernon Sondak, Daohai Yu, Weiwei Zhu, Clement Gwede, Ronald Deconti

Surgery Faculty Publications

Radiotherapy (RT) and interferon-alfa-2b (IFN α-2b) have individually been used for adjuvant therapy stage III melanoma with high-risk pathologic features. We hypothesized that concurrent adjuvant RT and IFN α-2b may decrease the risk of regional recurrence following surgery with acceptable toxicity. A prospective multicenter phase I/II study was conducted to evaluate hypofractionated RT with concurrent IFN. Induction IFN α-2b, 20 MU/m2/d, was administered IV ×5 consecutive days every week for 4 weeks. Next, RT 30 Gy in 5 fractions was given with concurrent IFN α-2b, 10 MU/m2 SQ 3 times per week on days alternating with …


“I Think, Therefore I Count”: Changing The Count Process While Encouraging Critical Thinking, Marlene H. Leidy, Hope L. Johnson MSN, RN, CNOR 2012 Lehigh Valley Health Network

“I Think, Therefore I Count”: Changing The Count Process While Encouraging Critical Thinking, Marlene H. Leidy, Hope L. Johnson Msn, Rn, Cnor

Patient Care Services / Nursing

No abstract provided.


Use Of Colour Duplex Ultrasound As A First Line Surveillance Tool Following Evar Is Associated With A Reduction In Cost Without Compromising Accuracy, C. Gray, Patrick J. Goodman, C. C. Herron, L. P. Lawler, M. K. O'Malley, M. K. O'Donohoe, C. O. Mc. Donnell 2012 Technological University Dublin

Use Of Colour Duplex Ultrasound As A First Line Surveillance Tool Following Evar Is Associated With A Reduction In Cost Without Compromising Accuracy, C. Gray, Patrick J. Goodman, C. C. Herron, L. P. Lawler, M. K. O'Malley, M. K. O'Donohoe, C. O. Mc. Donnell

Articles

CT scanning remains the postoperative surveillance imaging modality of choice following EVAR. Concerns regarding cost, exposure to ionising radiation and intravenous contrast have led to a search for a less expensive, equally efficacious and safer method of monitoring EVAR patients after endograft deployment. This study evaluated the cost saving obtained if CDUS was employed as a first line surveillance tool following EVAR, as well as comparing the two entities in terms of efficacy. Patients & methods: Postoperative surveillance CTs and CDUS scans in the 145 patients who have undergone EVAR from 1st June 2003 to 1st July 2010 were compared …


Contegra Valved Conduit In The Paediatric Population: An Exciting Prospect For Right Ventricle To Pulmonary Artery Reconstruction; Experience And Outcomes At Aga Khan University, Maria Tariq Siddiqui, Asif Hasan, Shazia Mohsin, Mohammad Hamid, Muneer Amanullah 2012 Liaquat National Hospital

Contegra Valved Conduit In The Paediatric Population: An Exciting Prospect For Right Ventricle To Pulmonary Artery Reconstruction; Experience And Outcomes At Aga Khan University, Maria Tariq Siddiqui, Asif Hasan, Shazia Mohsin, Mohammad Hamid, Muneer Amanullah

Department of Anaesthesia

Objective: The focus of this study is to share the experience and outcomes of Contegra graft implantation in the paediatric and adult population in Pakistan. Methods: Between May 2007 and July 2011, 16 patients, underwent implantation of a Contegra valved conduit. All operations were performed through a median sternotomy with cardiopulmonary bypass. Indications included: Pulmonary atresia with ventricular septal defect (n=11), Tetralogy of Fallot with absent Pulmonary Valve (PV) syndrome (n=2), double outlet right ventricle, transposition of great arteries and pulmonary stenosis (n=1), isolated aortic valve disease (n=1) and a pseudo-aneurysm with infective endocarditis (n=1).Conduit sizes varied between 16-22 mm. …


Infectious Intracranial Aneurysms: Collaboration For Treatment Success, Erin M. Conahan RN, BSN, CNRN 2012 Lehigh Valley Health Network

Infectious Intracranial Aneurysms: Collaboration For Treatment Success, Erin M. Conahan Rn, Bsn, Cnrn

Patient Care Services / Nursing

No abstract provided.


A Networkwide, Multidisciplinary Approach To Improving Perioperative Medication Safety, Diane Kimsey RN, MS, CNOR, Jeanne P. Luke MSN, RN, CNOR 2012 Lehigh Valley Health Network

A Networkwide, Multidisciplinary Approach To Improving Perioperative Medication Safety, Diane Kimsey Rn, Ms, Cnor, Jeanne P. Luke Msn, Rn, Cnor

Patient Care Services / Nursing

No abstract provided.


Dextrocardia With Situs Inversus Totalis: Coronary Artery Bypass Grafting, Salila Hashmi, Mariam Anis, Umer Darr 2012 Aga Khan University

Dextrocardia With Situs Inversus Totalis: Coronary Artery Bypass Grafting, Salila Hashmi, Mariam Anis, Umer Darr

Section of Cardiothoracic Surgery

Dextrocardia with situs inversus is a rare congenital abnormality involving a left-handed mal rotation of the visceral organs. The incidence of coronary artery disease is the same as that in the general population. Performing coronary artery bypass surgery on patients with dextrocardia poses a more challenging task. It is recommended that the right internal mammary artery be the first choice of graft for the anterior descending artery for a "situs inversus" situation. We report 2 cases of patients with Dextrocardia who developed coronary artery disease and underwent coronary artery bypass grafting. Also mentioned is the slight difference in our technique.


A Novel Survival-Based Tissue Microarray Of Pancreatic Cancer Validates Muc1 And Mesothelin As Biomarkers., Jordan M Winter, Laura H Tang, David S Klimstra, Murray F Brennan, Jonathan R Brody, Flavio G Rocha, Xiaoyu Jia, Li-Xuan Qin, Michael I D'Angelica, Ronald P Dematteo, Yuman Fong, William R Jarnagin, Eileen M O'Reilly, Peter J Allen 2012 Thomas Jefferson University

A Novel Survival-Based Tissue Microarray Of Pancreatic Cancer Validates Muc1 And Mesothelin As Biomarkers., Jordan M Winter, Laura H Tang, David S Klimstra, Murray F Brennan, Jonathan R Brody, Flavio G Rocha, Xiaoyu Jia, Li-Xuan Qin, Michael I D'Angelica, Ronald P Dematteo, Yuman Fong, William R Jarnagin, Eileen M O'Reilly, Peter J Allen

Department of Surgery Faculty Papers

BACKGROUND: One-fifth of patients with seemingly 'curable' pancreatic ductal adenocarcinoma (PDA) experience an early recurrence and death, receiving no definable benefit from a major operation. Some patients with advanced stage tumors are deemed 'unresectable' by conventional staging criteria (e.g. liver metastasis), yet progress slowly. Effective biomarkers that stratify PDA based on biologic behavior are needed. To help researchers sort through the maze of biomarker data, a compendium of ∼2500 published candidate biomarkers in PDA was compiled (PLoS Med, 2009. 6(4) p. e1000046).

METHODS AND FINDINGS: Building on this compendium, we constructed a survival tissue microarray (termed s-TMA) comprised of short-term …


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